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# **ZymCTRL**
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ZymCTRL ([Paper presented @ Machine Learning for Structural Biology workshop - December 2022](https://www.mlsb.io/papers_2022/ZymCTRL_a_conditional_language_model_for_the_controllable_generation_of_artificial_enzymes.pdf))
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is a conditional language model for the generation of artificial functional enzymes. It was trained on the entire BRENDA database of enzymes, comprising over 37 M sequences.
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Given a user-defined Enzymatic Commission (EC) number, the model generates protein sequences that fulfill that catalytic reaction.
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The generated sequences are ordered, globular, and distant to natural ones, while their intended catalytic properties match those defined by users.
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# **ZymCTRL**
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ZymCTRL (Enzyme Control) ([Paper presented @ Machine Learning for Structural Biology workshop - December 2022](https://www.mlsb.io/papers_2022/ZymCTRL_a_conditional_language_model_for_the_controllable_generation_of_artificial_enzymes.pdf))
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is a conditional language model for the generation of artificial functional enzymes. It was trained on the entire BRENDA database of enzymes, comprising over 37 M sequences.
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Given a user-defined Enzymatic Commission (EC) number, the model generates protein sequences that fulfill that catalytic reaction.
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The generated sequences are ordered, globular, and distant to natural ones, while their intended catalytic properties match those defined by users.
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