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---
license: cc-by-nc-nd-4.0
extra_gated_fields:
Name: text
Company: text
Country: country
Specific date: date_picker
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options:
- Research
- Education
- label: Other
value: other
I agree to share generated sequences and associated data with authors before publishing: checkbox
I agree not to file patents on any sequences generated by this model: checkbox
I agree to use this model for non-commercial use ONLY: checkbox
---
# MeMDLM: De Novo Membrane Protein Design with Masked Diffusion Language Models
Masked Diffusion Language Models (MDLMs), introduced by Sahoo et al (arxiv.org/pdf/2406.07524), provide strong generative capabilities to BERT-style models. In this work, we pre-train and fine-tune ESM-2-150M on the MDLM objective to unconditionally generate realistic, high-quality membrane protein sequences. |