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  # MeMDLM: De Novo Membrane Protein Design with Masked Diffusion Language Models
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- ![image/png](https://cdn-uploads.huggingface.co/production/uploads/65bbea9a26c639b000501321/uWW6xnJZwQFWDS1QZNQTm.png)
 
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  [Masked Diffusion Language Models (MDLMs)](arxiv.org/pdf/2406.07524), introduced by Sahoo et al, provide strong generative capabilities to BERT-style models. In this work, we pre-train and fine-tune ESM-2-150M protein language model (pLM) on the MDLM objective to scaffold functional motifs and unconditionally generate realistic, high-quality membrane protein sequences.
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  # MeMDLM: De Novo Membrane Protein Design with Masked Diffusion Language Models
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+ ![image/png](https://cdn-uploads.huggingface.co/production/uploads/65bbea9a26c639b000501321/QQoEGgvJddR2JfE7tzMSR.png)
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  [Masked Diffusion Language Models (MDLMs)](arxiv.org/pdf/2406.07524), introduced by Sahoo et al, provide strong generative capabilities to BERT-style models. In this work, we pre-train and fine-tune ESM-2-150M protein language model (pLM) on the MDLM objective to scaffold functional motifs and unconditionally generate realistic, high-quality membrane protein sequences.
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