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autophagosome assembly autophagosome maturation autophagy cell cycle cell division cellular response to glucose starvation cellular response to starvation early endosome to late endosome transport endocytosis endosome organization macroautophagy phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol phosphate biosynthetic process phosphatidylinositol-3-phosphate biosynthetic process phosphatidylinositol-mediated signaling phosphorylation protein localization to phagophore assembly site protein processing regulation of autophagy regulation of cytokinesis regulation of macroautophagy response to leucine |
apoptotic process apoptotic signaling pathway cellular response to type II interferon chromatin organization intracellular signal transduction negative regulation of translation neuron differentiation positive regulation of apoptotic process positive regulation of canonical Wnt signaling pathway positive regulation of cell migration positive regulation of extrinsic apoptotic signaling pathway in absence of ligand protein autophosphorylation regulation of actin cytoskeleton organization regulation of cell shape regulation of focal adhesion assembly regulation of mitotic cell cycle regulation of myosin II filament organization |
cellular response to lipopolysaccharide collagen catabolic process endodermal cell differentiation extracellular matrix organization ossification positive regulation of microglial cell activation positive regulation of neuroinflammatory response positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor-mediated signaling pathway protein catabolic process proteolysis |
axon guidance cell adhesion dendrite self-avoidance homophilic cell adhesion via plasma membrane adhesion molecules plasma membrane lactate transport |
keratinocyte proliferation memory neuron projection morphogenesis proteolysis regulation of synapse organization response to wounding synapse organization |
cytokine-mediated signaling pathway immunoglobulin mediated immune response negative regulation of immunoglobulin production negative regulation of mast cell degranulation |
actomyosin structure organization cell adhesion cell-cell adhesion cellular response to mechanical stimulus epithelial cell differentiation establishment of endothelial intestinal barrier intestinal absorption leukocyte cell-cell adhesion memory T cell extravasation negative regulation of stress fiber assembly positive regulation of blood pressure positive regulation of establishment of endothelial barrier positive regulation of platelet aggregation positive regulation of Rho protein signal transduction protein localization to bicellular tight junction protein localization to plasma membrane regulation of actin cytoskeleton organization regulation of bicellular tight junction assembly regulation of cell shape regulation of cytokine production regulation of cytoskeleton organization regulation of membrane permeability |
behavioral response to cocaine calcium-mediated signaling using intracellular calcium source G protein-coupled glutamate receptor signaling pathway negative regulation of calcineurin-NFAT signaling cascade negative regulation of interleukin-2 production regulation of G protein-coupled receptor signaling pathway regulation of store-operated calcium entry sensory perception of sound |
chromatin organization chromatin remodeling innate immune response nucleosome assembly post-translational protein modification stem cell population maintenance |
axon extension axoneme assembly brain development central nervous system projection neuron axonogenesis dendrite morphogenesis hippocampus development intracellular signal transduction layer formation in cerebral cortex neuron migration positive regulation of collateral sprouting positive regulation of endocytosis pyramidal neuron development retina development in camera-type eye |
protein transport signal transduction |
cellular response to insulin stimulus fatty acid metabolic process long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process positive regulation of long-chain fatty acid import across plasma membrane positive regulation of triglyceride biosynthetic process response to cholesterol response to glucose response to nutrient response to sucrose |
cellular response to cAMP circadian rhythm melatonin biosynthetic process N-terminal protein amino acid acetylation photoperiodism response to calcium ion response to copper ion response to corticosterone response to cytokine response to insulin response to light stimulus response to organic cyclic compound response to prostaglandin E response to zinc ion |
fucosylation glycosphingolipid biosynthetic process Lewis x epitope biosynthetic process N-glycan fucosylation nervous system development neuron differentiation neuronal stem cell division oligosaccharide biosynthetic process polysaccharide biosynthetic process positive regulation of neuron projection development protein glycosylation protein N-linked glycosylation protein O-linked glycosylation regulation of leukocyte cell-cell adhesion regulation of leukocyte tethering or rolling |
apoptotic mitochondrial changes mitotic cell cycle mitotic cytokinesis positive regulation of protein kinase activity regulation of cell population proliferation |
lipid metabolic process protein glycosylation |
CAMKK-AMPK signaling cascade positive regulation of protein phosphorylation protein autophosphorylation protein phosphorylation |
arachidonic acid metabolic process fatty acid metabolic process icosanoid biosynthetic process kidney development lauric acid metabolic process linoleic acid metabolic process |
intracellular signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination ubiquitin-dependent protein catabolic process |
angiogenesis cardiac epithelial to mesenchymal transition cell adhesion cellular response to phorbol 13-acetate 12-myristate collagen catabolic process immune response to tumor cell innate immune response integrin-mediated signaling pathway male gonad development negative regulation of cell growth negative regulation of cell migration negative regulation of cell-matrix adhesion proteolysis response to hypobaric hypoxia tissue regeneration |
2-oxoglutarate metabolic process female gonad development glutathione metabolic process glyoxylate cycle isocitrate metabolic process NADP metabolic process regulation of phospholipid biosynthetic process regulation of phospholipid catabolic process response to organic cyclic compound response to oxidative stress response to steroid hormone tricarboxylic acid cycle |
protein localization |
cellular response to arsenic-containing substance cellular response to cytokine stimulus cellular response to gamma radiation cellular response to hydroxyurea cellular response to testosterone stimulus male gonad development negative regulation of protein localization to chromatin positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process protein autoubiquitination protein K11-linked ubiquitination protein K48-linked ubiquitination protein K6-linked ubiquitination protein K63-linked ubiquitination protein ubiquitination regulation of kinetochore assembly regulation of spindle assembly response to arsenic-containing substance response to estradiol response to human chorionic gonadotropin spermatogenesis |
brain development cilium assembly fat cell differentiation intracellular protein transport protein localization to cilium protein localization to non-motile cilium protein polymerization protein targeting to membrane protein transport from ciliary membrane to plasma membrane Ras protein signal transduction regulation of smoothened signaling pathway retina layer formation vesicle-mediated transport Wnt signaling pathway |
fusion of sperm to egg plasma membrane involved in single fertilization peptidyl-tyrosine sulfation prevention of polyspermy |
de novo' NAD biosynthetic process from tryptophan anthranilate metabolic process cellular response to interleukin-1 cellular response to lipopolysaccharide kynurenic acid biosynthetic process kynurenine metabolic process L-kynurenine metabolic process NAD metabolic process positive regulation of glutamate secretion positive regulation of glutamate secretion, neurotransmission quinolinate biosynthetic process response to lipopolysaccharide response to salt stress tryptophan catabolic process |
endosomal transport intracellular transport protein targeting signal transduction |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway gamma-aminobutyric acid signaling pathway neuron-glial cell signaling synaptic transmission, GABAergic |
positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II |
cell cycle cell division DNA damage response in utero embryonic development negative regulation by host of viral genome replication negative regulation of stem cell differentiation positive regulation of DNA-templated transcription, elongation positive regulation of transcription elongation by RNA polymerase II regulation of signal transduction regulation of transcription by RNA polymerase II transcription by RNA polymerase II |
adaptive immune response defense response to Gram-negative bacterium innate immune response mucosal immune response negative regulation of adaptive immune memory response negative regulation of angiogenesis negative regulation of CD4-positive, alpha-beta T cell costimulation negative regulation of T cell receptor signaling pathway phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of endothelial cell apoptotic process positive regulation of natural killer cell cytokine production positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated immune response to tumor cell positive regulation of type II interferon production T cell costimulation |
bone morphogenesis cardiac septum morphogenesis negative regulation of retinoic acid receptor signaling pathway outflow tract morphogenesis regulation of ossification regulation of retinoic acid receptor signaling pathway retinoid metabolic process roof of mouth development |
face development fibroblast migration in utero embryonic development platelet-derived growth factor receptor signaling pathway respiratory system process skeletal system morphogenesis smooth muscle tissue development vasculature development |
antiviral innate immune response apoptotic process cellular response to cAMP cellular response to peptide hormone stimulus negative regulation of cardiac muscle hypertrophy negative regulation of protein dephosphorylation negative regulation of protein import into nucleus regulation of protein kinase A signaling |
cellular response to insulin stimulus insulin receptor signaling pathway intracellular signal transduction negative regulation of insulin receptor signaling pathway negative regulation of meiotic cell cycle process involved in oocyte maturation |
fat cell differentiation G1/S transition of mitotic cell cycle negative regulation of apoptotic process negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein localization to cell periphery positive regulation of protein sumoylation positive regulation of smooth muscle cell differentiation protein sumoylation protein-DNA complex assembly receptor signaling pathway via JAK-STAT regulation of cell population proliferation regulation of transcription by RNA polymerase II spermatogenesis visual learning |
cholesterol efflux cholesterol homeostasis cholesterol metabolic process cholesterol storage very-low-density lipoprotein particle assembly |
glutathione transport monoatomic ion transport prostaglandin transport quaternary ammonium group transport response to toxic substance |
neuron development neurotransmitter secretion regulation of short-term neuronal synaptic plasticity regulation of synaptic vesicle cycle regulation of synaptic vesicle exocytosis synapse organization synaptic vesicle clustering synaptic vesicle cycle |
B cell differentiation cartilage development chromatin organization chromatin remodeling DNA-templated transcription double-strand break repair via classical nonhomologous end joining erythrocyte maturation fat cell differentiation negative regulation of androgen receptor signaling pathway negative regulation of DNA-templated transcription negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of NF-kappaB transcription factor activity protein localization to nucleus regulation of alternative mRNA splicing, via spliceosome regulation of apoptotic process regulation of DNA-binding transcription factor activity regulation of DNA-templated transcription regulation of glycolytic process regulation of osteoclast differentiation regulation of transcription by RNA polymerase II regulation of transcription regulatory region DNA binding |
branchiomeric skeletal muscle development cellular response to leukemia inhibitory factor diaphragm development negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II roof of mouth development skeletal muscle tissue development |
action potential initiation apoptosome assembly cellular response to ammonium ion cellular response to calcium ion cellular response to xenobiotic stimulus endocytosis establishment of localization in cell excitatory chemical synaptic transmission exocytosis ganglion development gene expression inhibitory chemical synaptic transmission membrane hyperpolarization mitochondrial depolarization monoatomic ion transmembrane transport nerve development neuron apoptotic process neuron differentiation neuron remodeling neuronal action potential oligodendrocyte development potassium ion transmembrane transport protein import into nucleus protein targeting protein transport protein-containing complex assembly psychomotor behavior regulation of action potential firing threshold regulation of synaptic plasticity response to auditory stimulus response to mechanical stimulus response to organic cyclic compound sensory perception of sound substantia propria of cornea development |
blood coagulation positive regulation of TOR signaling proteolysis |
exocytosis maintenance of epithelial cell apical/basal polarity neurotransmitter secretion protein localization to basolateral plasma membrane protein transport |
exocytosis maintenance of epithelial cell apical/basal polarity morphogenesis of an epithelial sheet neurotransmitter secretion protein localization to basolateral plasma membrane protein transport |
ceramide metabolic process phospholipid dephosphorylation phospholipid metabolic process signal transduction sphingosine metabolic process |
acrosome reaction fructose 6-phosphate metabolic process fructose biosynthetic process generation of precursor metabolites and energy glucosamine catabolic process glucosamine metabolic process N-acetylglucosamine catabolic process N-acetylneuraminate catabolic process UDP-N-acetylglucosamine biosynthetic process |
bile acid biosynthetic process positive regulation of intestinal cholesterol absorption |
cell population proliferation mitochondrial protein catabolic process mitochondrial protein processing mitochondrion organization negative regulation of apoptotic process protein hexamerization protein quality control for misfolded or incompletely synthesized proteins |
cellular response to type II interferon early endosome to late endosome transport endosome to lysosome transport intracellular protein transport regulation of protein localization to plasma membrane vesicle docking vesicle fusion vesicle-mediated transport |
mRNA export from nucleus poly(A)+ mRNA export from nucleus protein transport RNA export from nucleus |
blastocyst hatching protein localization transmembrane receptor protein serine/threonine kinase signaling pathway |
malate metabolic process NAD metabolic process NADH metabolic process NADP metabolic process oxaloacetate metabolic process tricarboxylic acid cycle |
actin cytoskeleton organization bone morphogenesis focal adhesion assembly muscle cell development muscle contraction negative regulation of calcineurin-NFAT signaling cascade negative regulation of cold-induced thermogenesis negative regulation of glycolytic process negative regulation of oxidative phosphorylation negative regulation of relaxation of muscle positive regulation of bone mineralization involved in bone maturation positive regulation of fast-twitch skeletal muscle fiber contraction positive regulation of glucose catabolic process to lactate via pyruvate positive regulation of skeletal muscle fiber development positive regulation of skeletal muscle tissue growth regulation of aerobic respiration regulation of muscle system process regulation of the force of skeletal muscle contraction response to denervation involved in regulation of muscle adaptation skeletal muscle atrophy transition between fast and slow fiber |
maintenance of synapse structure motor learning neuron remodeling regulation of synapse pruning |
cellular response to leukemia inhibitory factor cobalamin metabolic process cobalamin transport fatty acid beta-oxidation long-chain fatty acid import into peroxisome peroxisome organization very long-chain fatty acid catabolic process |
antigen processing and presentation of exogenous peptide antigen via MHC class II associative learning cellular response to amyloid-beta cellular response to calcium ion cellular response to hepatocyte growth factor stimulus dendritic spine organization memory negative regulation of ERBB signaling pathway negative regulation of gene expression negative regulation of multicellular organism growth negative regulation of neuron apoptotic process positive regulation of cell population proliferation positive regulation of endothelial cell chemotaxis positive regulation of long-term synaptic potentiation positive regulation of mitotic cell cycle positive regulation of monocyte chemotaxis protein maturation proteolysis proteolysis involved in protein catabolic process receptor catabolic process renal system process response to acidic pH self proteolysis vacuolar protein processing |
protein stabilization protein transport within extracellular region vitamin transport |
bone resorption central nervous system development epithelial cell differentiation lysosomal protein catabolic process lysosome organization nervous system development neuromuscular process controlling balance peptide catabolic process protein catabolic process protein localization to chromosome, telomeric region proteolysis |
cell division DNA replication initiation mitotic DNA replication checkpoint signaling positive regulation of chromosome segregation positive regulation of cytokinesis positive regulation of fibroblast proliferation regulation of mitotic metaphase/anaphase transition |
glyceraldehyde-3-phosphate biosynthetic process lipid transport malate transmembrane transport malate transport oxaloacetate transport phosphate ion transmembrane transport phosphate ion transport succinate transmembrane transport succinate transport sulfate transport thiosulfate transport |
adult heart development apoptotic process cell differentiation chondrocyte differentiation endochondral ossification nervous system development osteoblast differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of vascular associated smooth muscle cell proliferation regulation of DNA-templated transcription skeletal muscle cell differentiation |
angiogenesis calcium-mediated signaling cell adhesion cell chemotaxis chemokine-mediated signaling pathway immune response negative regulation of cell population proliferation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage oculomotor nerve development positive regulation of cytosolic calcium ion concentration positive regulation of ERK1 and ERK2 cascade positive regulation of mesenchymal stem cell migration receptor internalization vasculogenesis |
actin cytoskeleton organization actin filament branching actin filament bundle assembly actin filament organization cell migration cellular response to platelet-derived growth factor stimulus endothelial cell chemotaxis negative regulation of Arp2/3 complex-mediated actin nucleation negative regulation of lamellipodium morphogenesis negative regulation of smooth muscle cell chemotaxis positive regulation of lamellipodium morphogenesis protein kinase C signaling protein localization to cell leading edge regulation of Arp2/3 complex-mediated actin nucleation ruffle organization wound healing |
benzene-containing compound metabolic process cell population proliferation cell redox homeostasis cellular response to copper ion cellular response to hyperoxia gastrulation halogen metabolic process hydrogen peroxide catabolic process mesoderm formation NADPH oxidation positive regulation of apoptotic process response to axon injury response to hyperoxia response to oxidative stress response to selenium ion response to xenobiotic stimulus selenocysteine metabolic process |
actin cytoskeleton organization cell-matrix adhesion regulation of cell shape regulation of receptor internalization |
negative regulation of amyloid precursor protein biosynthetic process |
cAMP catabolic process cellular response to xenobiotic stimulus modulation of chemical synaptic transmission regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of protein kinase A signaling sensory perception of smell signal transduction |
miRNA processing positive regulation of mRNA splicing, via spliceosome positive regulation of translation regulation of translation response to cold translation |
bone mineralization cellular response to starvation circadian rhythm negative regulation of DNA-templated transcription positive regulation of osteoclast differentiation positive regulation of transcription by RNA polymerase II regulation of circadian rhythm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II somatic stem cell population maintenance |
antimicrobial humoral immune response mediated by antimicrobial peptide calcium-mediated signaling using intracellular calcium source cell chemotaxis cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis G protein-coupled receptor signaling pathway inflammatory response killing of cells of another organism lymphocyte chemotaxis monocyte chemotaxis neutrophil chemotaxis positive regulation of ERK1 and ERK2 cascade positive regulation of interleukin-1 alpha production positive regulation of nitric-oxide synthase biosynthetic process positive regulation of T cell migration T cell migration thymocyte migration |
cell differentiation proteolysis |
immune response negative regulation of microglial cell activation negative regulation of peptidase activity positive regulation of myelination |
regulation of MAPK cascade signal transduction |
angiogenesis animal organ morphogenesis cell differentiation cell population proliferation chondrocyte development chondrocyte differentiation endochondral ossification ERK1 and ERK2 cascade fibroblast growth factor receptor signaling pathway intramembranous ossification lung development nervous system development ossification positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of cell population proliferation positive regulation of chondrocyte differentiation positive regulation of endothelial cell chemotaxis to fibroblast growth factor positive regulation of ERK1 and ERK2 cascade positive regulation of gene expression positive regulation of hepatocyte proliferation positive regulation of protein phosphorylation positive regulation of vascular endothelial growth factor receptor signaling pathway regulation of cell migration signal transduction vascular endothelial growth factor receptor signaling pathway |
cell-cell adhesion |
diadenosine triphosphate catabolic process DNA replication intrinsic apoptotic signaling pathway by p53 class mediator negative regulation of proteasomal ubiquitin-dependent protein catabolic process purine nucleotide metabolic process |
apoptotic DNA fragmentation DNA catabolic process neutrophil activation involved in immune response programmed cell death involved in cell development regulation of acute inflammatory response regulation of neutrophil mediated cytotoxicity |
carbohydrate metabolic process cellular detoxification peptide modification |
autophagy endocytic recycling endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to vacuole transport intra-Golgi vesicle-mediated transport intracellular protein transport macroautophagy retrograde transport, endosome to Golgi synaptic vesicle to endosome fusion vesicle fusion with Golgi apparatus voluntary musculoskeletal movement |
viral budding via host ESCRT complex |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy |
viral budding via host ESCRT complex |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy |
viral budding via host ESCRT complex |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy |
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response |
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response |
proteolysis viral procapsid maturation |
viral budding via host ESCRT complex |
cell migration embryo development ending in birth or egg hatching gastrulation kidney field specification mRNA stabilization negative regulation of nuclear-transcribed mRNA poly(A) tail shortening neurogenesis positive regulation of translation pronephros development response to cold response to UV stress granule assembly |
apoptotic process GTP metabolic process inner mitochondrial membrane organization membrane tubulation mitochondrial fusion negative regulation of apoptotic process visual perception |
cellular response to gamma radiation DNA recombination double-strand break repair via nonhomologous end joining negative regulation of DNA-templated transcription telomere maintenance |
canonical Wnt signaling pathway positive regulation of DNA-binding transcription factor activity |
nucleosome assembly regulation of NAD metabolic process |
heart looping heart morphogenesis positive regulation of gene expression protein homotetramerization response to retinoic acid retinoic acid biosynthetic process retinoic acid metabolic process retinol metabolic process spinal cord motor neuron differentiation |
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