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1792
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1800
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1803
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1817
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1818
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1819
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1820
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1821
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1822
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1823
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1824
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1825
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1826
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1827
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1828
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1829
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1830
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1831
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1832
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1833
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1834
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1835
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1836
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1837
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1838
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1839
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1840
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1841
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1842
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1843
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1844
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1845
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1846
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1847
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1848
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1849
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1850
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1851
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1852
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1853
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1854
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1855
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1856
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1857
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1858
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1859
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1860
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1861
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1862
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1863
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1864
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1865
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1866
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1867
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1868
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1869
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1870
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1871
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1872
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1873
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1874
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1875
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1876
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1877
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1878
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1879
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1880
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1881
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1882
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1883
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1884
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1885
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1886
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1887
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1888
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1889
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1890
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1891
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1892
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1893
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1894
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1895
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1896
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1897
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1898
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1899
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1900
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1901
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1902
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1903
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1904
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1905
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1906
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1907
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1908
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1909
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1910
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1911
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1912
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1913
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1914
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1915
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1916
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1917
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1918
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1919
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1920
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1921
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1922
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1923
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1924
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1925
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1926
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1927
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1928
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1929
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1930
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1931
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1932
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1933
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1934
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1935
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1936
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1937
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1938
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1939
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1940
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1941
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1942
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1943
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1944
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1945
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1946
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1947
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1948
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1949
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1950
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1951
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1952
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1953
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1954
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1955
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1956
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1957
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1958
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1959
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1960
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1961
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1962
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1963
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1964
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1965
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1966
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1967
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1968
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1969
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1970
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1971
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1972
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1973
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1974
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1975
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1976
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1977
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1978
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1979
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1980
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1981
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1982
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1983
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1984
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1985
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1986
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1987
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1988
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1989
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1990
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1991
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1992
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1993
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1994
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1995
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1996
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1997
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1998
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1999
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2000
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2001
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2002
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2003
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2004
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2005
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2006
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2007
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2008
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2009
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2010
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2011
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2012
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2013
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2014
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2015
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2016
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2017
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2018
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2019
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2020
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2021
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2022
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2023
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2025
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2027
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2028
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2029
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2030
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2031
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2032
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2033
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2035
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2036
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2037
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2038
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2039
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2040
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2041
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2042
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2043
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2044
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2045
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2046
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2047
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2048
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2049
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2050
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2051
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2052
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2053
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2054
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2055
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2056
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2057
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2058
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2059
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2060
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2061
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2062
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2063
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2064
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2065
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2066
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2067
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2068
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2069
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2070
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2071
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2072
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2073
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2074
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2075
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2076
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2077
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2078
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2079
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2080
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2081
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2082
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2083
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2084
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2085
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2086
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2087
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2088
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2089
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2090
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2091
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2092
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2093
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2094
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2095
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2096
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2097
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2098
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2099
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2100
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2101
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2102
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2103
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2104
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2105
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2106
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2107
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2108
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2109
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2110
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2111
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2112
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2113
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2114
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2115
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2116
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2117
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2118
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2119
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2120
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2121
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2122
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2123
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2124
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2125
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2127
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2128
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2129
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2130
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2131
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2132
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2133
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2134
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2135
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2136
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2137
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2138
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2139
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2140
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2141
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2142
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2143
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2144
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2145
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2146
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2147
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2148
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2149
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2150
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2151
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2152
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2153
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2154
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2155
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2156
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2157
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2158
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2159
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2160
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2161
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2162
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2163
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2164
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2166
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2167
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2168
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2169
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2170
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2171
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2172
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2174
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2175
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2176
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2177
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2178
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2179
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2180
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2181
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2182
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2183
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2184
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2186
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2187
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2188
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2189
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2190
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2191
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2192
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2193
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2194
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2195
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2196
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2197
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2198
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2200
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2201
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2202
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2203
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2204
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2205
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2206
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2208
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2209
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2210
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2211
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2213
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2214
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2215
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2216
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2217
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2218
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2220
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2222
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2240
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2248
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2249
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2250
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2251
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2253
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processed/inductive/train_df.csv ADDED
The diff for this file is too large to render. See raw diff
 
processed/inductive/val_df.csv ADDED
The diff for this file is too large to render. See raw diff
 
processed/transductive/test_df.csv ADDED
The diff for this file is too large to render. See raw diff
 
processed/transductive/train_df.csv ADDED
The diff for this file is too large to render. See raw diff
 
processed/transductive/val_df.csv ADDED
The diff for this file is too large to render. See raw diff
 
raw/DATA-DESCRIPTION.txt ADDED
@@ -0,0 +1,44 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Each timestamped simplex dataset consists of three files:
2
+ 1. dataset-nverts.txt
3
+ 2. dataset-simplices.txt
4
+ 3. dataset-times.txt
5
+
6
+ All three files represent a vector of integers. There is one integer per line.
7
+
8
+ The first file contains the number of vertices within each simplex. The second
9
+ file is a contiguous list of the nodes comprising the simplices, where the
10
+ ordering of the simplices is the same as in the first file. The third file
11
+ contains the timestamps for each simplex. The length of the vectors in the first
12
+ and third files is the same, and the length of the vector in the second file is
13
+ the sum of the integers in the first file.
14
+
15
+ Consider an example dataset consisting of three simplices:
16
+ 1. {1, 2, 3} at time 10
17
+ 2. {2, 4} at time 15.
18
+ 3. {1, 3, 4, 5} at time 21.
19
+ Then files would look as follows:
20
+
21
+ example-nverts.txt
22
+ 3
23
+ 2
24
+ 4
25
+
26
+ example-simplices.xt
27
+ 1
28
+ 2
29
+ 3
30
+ 2
31
+ 4
32
+ 1
33
+ 3
34
+ 4
35
+ 5
36
+
37
+ example-times.txt
38
+ 10
39
+ 15
40
+ 21
41
+
42
+
43
+
44
+ For problems, please contact Austin Benson at [email protected].
raw/NDC-classes-full-node-labels.txt ADDED
@@ -0,0 +1,1161 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ 1 radioactive diagnostic agent [epc]
2
+ 2 positron emitting activity [moa]
3
+ 3 antiarrhythmic [epc]
4
+ 4 cytochrome p450 2d6 inhibitor [epc]
5
+ 5 cytochrome p450 2d6 inhibitors [moa]
6
+ 6 glp-1 receptor agonist [epc]
7
+ 7 glucagon-like peptide 1 [chemical/ingredient]
8
+ 8 glucagon-like peptide-1 (glp-1) agonists [moa]
9
+ 9 interleukin-17a antagonist [epc]
10
+ 10 interleukin-17a antagonists [moa]
11
+ 11 androgen [epc]
12
+ 12 androgen receptor agonists [moa]
13
+ 13 androstanes [chemical/ingredient]
14
+ 14 serotonin reuptake inhibitor [epc]
15
+ 15 serotonin uptake inhibitors [moa]
16
+ 16 norepinephrine reuptake inhibitor [epc]
17
+ 17 norepinephrine uptake inhibitors [moa]
18
+ 18 atypical antipsychotic [epc]
19
+ 19 serotonin and norepinephrine reuptake inhibitor [epc]
20
+ 20 estrogen agonist/antagonist [epc]
21
+ 21 selective estrogen receptor modulators [moa]
22
+ 22 phosphodiesterase 5 inhibitor [epc]
23
+ 23 phosphodiesterase 5 inhibitors [moa]
24
+ 24 decreased platelet aggregation [pe]
25
+ 25 p2y12 platelet inhibitor [epc]
26
+ 26 p2y12 receptor antagonists [moa]
27
+ 27 nucleic acid synthesis inhibitors [moa]
28
+ 28 nucleoside metabolic inhibitor [epc]
29
+ 29 insulin [chemical/ingredient]
30
+ 30 insulin analog [epc]
31
+ 31 folate analog metabolic inhibitor [epc]
32
+ 32 folic acid metabolism inhibitors [moa]
33
+ 33 vascular endothelial growth factor receptor 2 antagonist [epc]
34
+ 34 vegfr2 inhibitors [moa]
35
+ 35 epidermal growth factor receptor antagonist [epc]
36
+ 36 her1 antagonists [moa]
37
+ 37 parathyroid hormone [chemical/ingredient]
38
+ 38 parathyroid hormone analog [epc]
39
+ 39 insulin [epc]
40
+ 40 hepatitis c virus ns5a inhibitor [epc]
41
+ 41 p-glycoprotein inhibitors [moa]
42
+ 42 organic anion transporting polypeptide 1b1 inhibitors [moa]
43
+ 43 organic anion transporting polypeptide 1b3 inhibitors [moa]
44
+ 44 breast cancer resistance protein inhibitors [moa]
45
+ 45 corticosteroid [epc]
46
+ 46 corticosteroid hormone receptor agonists [moa]
47
+ 47 t lymphocyte costimulation activity blockade [pe]
48
+ 48 selective t cell costimulation blocker [epc]
49
+ 49 cd80-directed antibody interactions [moa]
50
+ 50 cd86-directed antibody interactions [moa]
51
+ 51 kinase inhibitor [epc]
52
+ 52 protein kinase inhibitors [moa]
53
+ 53 cytochrome p450 3a4 inhibitors [moa]
54
+ 54 antimetabolite [epc]
55
+ 55 urea [chemical/ingredient]
56
+ 56 factor xa inhibitor [epc]
57
+ 57 factor xa inhibitors [moa]
58
+ 58 hepatitis b virus nucleoside analog reverse transcriptase inhibitor [epc]
59
+ 59 nucleoside analog [chemical/ingredient]
60
+ 60 nucleoside reverse transcriptase inhibitors [moa]
61
+ 61 human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor [epc]
62
+ 62 decreased cytokine activity [pe]
63
+ 63 selective t cell costimulation modulator [epc]
64
+ 64 recombinant fusion proteins [chemical/ingredient]
65
+ 65 monobactam antibacterial [epc]
66
+ 66 monobactams [chemical/ingredient]
67
+ 67 slamf7-directed immunostimulatory antibody [epc]
68
+ 68 slamf7-directed antibody interactions [moa]
69
+ 69 antibodies
70
+ 70 monoclonal [chemical/ingredient]
71
+ 71 ctla-4-directed blocking antibody [epc]
72
+ 72 ctla-4-directed antibody interactions [moa]
73
+ 73 increased t lymphocyte activation [pe]
74
+ 74 hiv protease inhibitors [moa]
75
+ 75 protease inhibitor [epc]
76
+ 76 ugt1a1 inhibitors [moa]
77
+ 77 udp glucuronosyltransferases inhibitors [moa]
78
+ 78 cytochrome p450 3a inhibitors [moa]
79
+ 79 cytochrome p450 2c8 inhibitors [moa]
80
+ 80 cytochrome p450 3a inhibitor [epc]
81
+ 81 programmed death receptor-1 blocking antibody [epc]
82
+ 82 programmed death receptor-1-directed antibody interactions [moa]
83
+ 83 hmg-coa reductase inhibitor [epc]
84
+ 84 hydroxymethylglutaryl-coa reductase inhibitors [moa]
85
+ 85 cytomegalovirus nucleoside analog dna polymerase inhibitor [epc]
86
+ 86 dna polymerase inhibitors [moa]
87
+ 87 nucleoside analog antiviral [epc]
88
+ 88 benzodiazepine [epc]
89
+ 89 benzodiazepines [chemical/ingredient]
90
+ 90 bisphosphonate [epc]
91
+ 91 diphosphonates [chemical/ingredient]
92
+ 92 intestinal lipase inhibitor [epc]
93
+ 93 lipase inhibitors [moa]
94
+ 94 antimetabolite immunosuppressant [epc]
95
+ 95 interferon alpha [epc]
96
+ 96 peginterferon alfa-2a [chemical/ingredient]
97
+ 97 erythropoiesis-stimulating agent [epc]
98
+ 98 erythropoietin [chemical/ingredient]
99
+ 99 increased erythroid cell production [pe]
100
+ 100 cyclooxygenase inhibitors [moa]
101
+ 101 nonsteroidal anti-inflammatory compounds [chemical/ingredient]
102
+ 102 nonsteroidal anti-inflammatory drug [epc]
103
+ 103 inactivated pneumococcal vaccine [epc]
104
+ 104 actively acquired immunity [pe]
105
+ 105 vaccines
106
+ 106 inactivated [chemical/ingredient]
107
+ 107 pneumococcal vaccines [chemical/ingredient]
108
+ 108 conjugate [chemical/ingredient]
109
+ 109 orexin receptor antagonist [epc]
110
+ 110 orexin receptor antagonists [moa]
111
+ 111 angiotensin converting enzyme inhibitor [epc]
112
+ 112 angiotensin-converting enzyme inhibitors [moa]
113
+ 113 antiparasitic [epc]
114
+ 114 pediculicide [epc]
115
+ 115 5-alpha reductase inhibitor [epc]
116
+ 116 5-alpha reductase inhibitors [moa]
117
+ 117 dipeptidyl peptidase 4 inhibitor [epc]
118
+ 118 dipeptidyl peptidase 4 inhibitors [moa]
119
+ 119 biguanide [epc]
120
+ 120 biguanides [chemical/ingredient]
121
+ 121 hiv integrase inhibitors [moa]
122
+ 122 human immunodeficiency virus integrase strand transfer inhibitor [epc]
123
+ 123 serotonin 1b receptor agonists [moa]
124
+ 124 serotonin 1d receptor agonists [moa]
125
+ 125 serotonin-1b and serotonin-1d receptor agonist [epc]
126
+ 126 vitamin d [chemical/ingredient]
127
+ 127 vitamin d [epc]
128
+ 128 protease-activated receptor-1 antagonist [epc]
129
+ 129 protease-activated receptor-1 antagonists [moa]
130
+ 130 neurokinin 1 antagonists [moa]
131
+ 131 substance p/neurokinin-1 receptor antagonist [epc]
132
+ 132 cytochrome p450 2c9 inducers [moa]
133
+ 133 cytochrome p450 3a4 inducers [moa]
134
+ 134 histone deacetylase inhibitor [epc]
135
+ 135 histone deacetylase inhibitors [moa]
136
+ 136 angiotensin 2 receptor antagonists [moa]
137
+ 137 angiotensin 2 receptor blocker [epc]
138
+ 138 increased diuresis [pe]
139
+ 139 thiazide diuretic [epc]
140
+ 140 thiazides [chemical/ingredient]
141
+ 141 leukotriene receptor antagonist [epc]
142
+ 142 leukotriene receptor antagonists [moa]
143
+ 143 hcv ns3/4a protease inhibitors [moa]
144
+ 144 hepatitis c virus ns3/4a protease inhibitor [epc]
145
+ 145 dipeptidase inhibitors [moa]
146
+ 146 renal dehydropeptidase inhibitor [epc]
147
+ 147 carbapenems [chemical/ingredient]
148
+ 148 penem antibacterial [epc]
149
+ 149 carbonic anhydrase inhibitor [epc]
150
+ 150 carbonic anhydrase inhibitors [moa]
151
+ 151 echinocandin antifungal [epc]
152
+ 152 lipopeptides [chemical/ingredient]
153
+ 153 aromatic amino acid [epc]
154
+ 154 amino acids
155
+ 155 aromatic [chemical/ingredient]
156
+ 156 inactivated human papillomavirus vaccine [epc]
157
+ 157 papillomavirus vaccines [chemical/ingredient]
158
+ 158 live rotavirus vaccine [epc]
159
+ 159 rotavirus vaccines [chemical/ingredient]
160
+ 160 live
161
+ 161 unattenuated [chemical/ingredient]
162
+ 162 inactivated hepatitis b virus vaccine [epc]
163
+ 163 hepatitis b vaccines [chemical/ingredient]
164
+ 164 inactivated hepatitis a virus vaccine [epc]
165
+ 165 hepatitis a vaccines [chemical/ingredient]
166
+ 166 live attenuated measles virus vaccine [epc]
167
+ 167 attenuated [chemical/ingredient]
168
+ 168 measles vaccine [chemical/ingredient]
169
+ 169 live attenuated mumps virus vaccine [epc]
170
+ 170 mumps vaccine [chemical/ingredient]
171
+ 171 live attenuated rubella virus vaccine [epc]
172
+ 172 rubella vaccine [chemical/ingredient]
173
+ 173 live attenuated varicella zoster virus vaccine [epc]
174
+ 174 chickenpox vaccine [chemical/ingredient]
175
+ 175 live attenuated herpes zoster virus vaccine [epc]
176
+ 176 herpes zoster vaccine [chemical/ingredient]
177
+ 177 standardized pollen allergenic extract [epc]
178
+ 178 increased histamine release [pe]
179
+ 179 cell-mediated immunity [pe]
180
+ 180 increased igg production [pe]
181
+ 181 pollen [chemical/ingredient]
182
+ 182 allergens [chemical/ingredient]
183
+ 183 tumor necrosis factor blocker [epc]
184
+ 184 tumor necrosis factor receptor blocking activity [moa]
185
+ 185 inactivated haemophilus influenzae b vaccine [epc]
186
+ 186 haemophilus vaccines [chemical/ingredient]
187
+ 187 gamma-cyclodextrins [chemical/ingredient]
188
+ 188 adrenergic alpha-antagonists [moa]
189
+ 189 adrenergic beta1-antagonists [moa]
190
+ 190 adrenergic beta2-antagonists [moa]
191
+ 191 alpha-adrenergic blocker [epc]
192
+ 192 beta-adrenergic blocker [epc]
193
+ 193 decreased renal k+ excretion [pe]
194
+ 194 potassium-sparing diuretic [epc]
195
+ 195 topoisomerase inhibitor [epc]
196
+ 196 topoisomerase inhibitors [moa]
197
+ 197 anti-coagulant [epc]
198
+ 198 direct thrombin inhibitor [epc]
199
+ 199 thrombin inhibitors [moa]
200
+ 200 increased megakaryocyte maturation [pe]
201
+ 201 increased platelet production [pe]
202
+ 202 thrombopoietin receptor agonist [epc]
203
+ 203 thrombopoietin receptor agonists [moa]
204
+ 204 ugt1a3 inhibitors [moa]
205
+ 205 ugt1a4 inhibitors [moa]
206
+ 206 ugt1a6 inhibitors [moa]
207
+ 207 ugt1a9 inhibitors [moa]
208
+ 208 ugt2b7 inhibitors [moa]
209
+ 209 ugt2b15 inhibitors [moa]
210
+ 210 dopamine agonists [moa]
211
+ 211 nonergot dopamine agonist [epc]
212
+ 212 vinca alkaloid [epc]
213
+ 213 vinca alkaloids [chemical/ingredient]
214
+ 214 proton pump inhibitor [epc]
215
+ 215 proton pump inhibitors [moa]
216
+ 216 decreased immunologic activity [pe]
217
+ 217 mtor inhibitor immunosuppressant [epc]
218
+ 218 mtor inhibitors [moa]
219
+ 219 estrogen [epc]
220
+ 220 estrogen receptor agonists [moa]
221
+ 221 estrogens
222
+ 222 conjugated (usp) [chemical/ingredient]
223
+ 223 antimycobacterial [epc]
224
+ 224 cd33-directed cytotoxin [epc]
225
+ 225 tetracycline-class antibacterial [epc]
226
+ 226 tetracyclines [chemical/ingredient]
227
+ 227 progesterone congeners [chemical/ingredient]
228
+ 228 progestin [epc]
229
+ 229 decreased sebaceous gland activity [pe]
230
+ 230 lincosamide antibacterial [epc]
231
+ 231 lincosamides [chemical/ingredient]
232
+ 232 decreased cell wall synthesis & repair [pe]
233
+ 233 bile acid sequestrant [epc]
234
+ 234 bile-acid binding activity [moa]
235
+ 235 estradiol congeners [chemical/ingredient]
236
+ 236 sulfonylurea [epc]
237
+ 237 sulfonylurea compounds [chemical/ingredient]
238
+ 238 prostaglandin analog [epc]
239
+ 239 prostaglandins [chemical/ingredient]
240
+ 240 genitourinary arterial vasodilation [pe]
241
+ 241 prostaglandin e1 agonist [epc]
242
+ 242 prostaglandin receptor agonists [moa]
243
+ 243 venous vasodilation [pe]
244
+ 244 cholinergic muscarinic antagonist [epc]
245
+ 245 cholinergic muscarinic antagonists [moa]
246
+ 246 oxazolidinone antibacterial [epc]
247
+ 247 oxazolidinones [chemical/ingredient]
248
+ 248 alpha glucosidase inhibitors [moa]
249
+ 249 alpha-glucosidase inhibitor [epc]
250
+ 250 anthracycline topoisomerase inhibitor [epc]
251
+ 251 anthracyclines [chemical/ingredient]
252
+ 252 cholinergic nicotinic agonist [epc]
253
+ 253 nicotine [chemical/ingredient]
254
+ 254 immunoglobulin g [epc]
255
+ 255 lymphocyte function alteration [pe]
256
+ 256 increased t lymphocyte destruction [pe]
257
+ 257 antibody-surface protein interactions [moa]
258
+ 258 immunoglobulins [chemical/ingredient]
259
+ 259 aromatase inhibitor [epc]
260
+ 260 aromatase inhibitors [moa]
261
+ 261 aminosalicylate [epc]
262
+ 262 aminosalicylic acids [chemical/ingredient]
263
+ 263 alkylating activity [moa]
264
+ 264 alkylating drug [epc]
265
+ 265 estradiol [chemical/ingredient]
266
+ 266 nitrogen mustard compounds [chemical/ingredient]
267
+ 267 antifibrinolytic agent [epc]
268
+ 268 decreased fibrinolysis [pe]
269
+ 269 rifamycin antimycobacterial [epc]
270
+ 270 rifamycins [chemical/ingredient]
271
+ 271 cytoprotective agent [epc]
272
+ 272 radiographic contrast agent [epc]
273
+ 273 x-ray contrast activity [moa]
274
+ 274 gadolinium-based contrast agent [epc]
275
+ 275 magnetic resonance contrast activity [moa]
276
+ 276 osmotic laxative [epc]
277
+ 277 increased large intestinal motility [pe]
278
+ 278 inhibition large intestine fluid/electrolyte absorption [pe]
279
+ 279 osmotic activity [moa]
280
+ 280 retinoid [epc]
281
+ 281 retinoids [chemical/ingredient]
282
+ 282 aminoglycoside antibacterial [epc]
283
+ 283 aminoglycosides [chemical/ingredient]
284
+ 284 sulfonamide antibacterial [epc]
285
+ 285 sulfonamides [chemical/ingredient]
286
+ 286 acetylcholine release inhibitor [epc]
287
+ 287 acetylcholine release inhibitors [moa]
288
+ 288 cyclooxygenase inhibitor [epc]
289
+ 289 quinolone antimicrobial [epc]
290
+ 290 quinolones [chemical/ingredient]
291
+ 291 sulfone [epc]
292
+ 292 sulfones [chemical/ingredient]
293
+ 293 histamine h1 receptor antagonists [moa]
294
+ 294 histamine-1 receptor antagonist [epc]
295
+ 295 adrenergic beta-antagonists [moa]
296
+ 296 antiprotozoal [epc]
297
+ 297 decarboxylase inhibitor [epc]
298
+ 298 decarboxylase inhibitors [moa]
299
+ 299 vasoconstrictor [epc]
300
+ 300 vasoconstriction [pe]
301
+ 301 increased sympathetic activity [pe]
302
+ 302 imidazolines [chemical/ingredient]
303
+ 303 calcineurin inhibitor immunosuppressant [epc]
304
+ 304 calcineurin inhibitors [moa]
305
+ 305 inhibit ovum fertilization [pe]
306
+ 306 progestin-containing intrauterine device [epc]
307
+ 307 nitroimidazole antimicrobial [epc]
308
+ 308 nitroimidazoles [chemical/ingredient]
309
+ 309 opioid agonist [epc]
310
+ 310 opioid agonists [moa]
311
+ 311 barbiturate [epc]
312
+ 312 barbiturates [chemical/ingredient]
313
+ 313 decreased prostaglandin production [pe]
314
+ 314 platelet aggregation inhibitor [epc]
315
+ 315 central nervous system stimulant [epc]
316
+ 316 central nervous system stimulation [pe]
317
+ 317 methylxanthine [epc]
318
+ 318 xanthines [chemical/ingredient]
319
+ 319 full opioid agonists [moa]
320
+ 320 polymyxin-class antibacterial [epc]
321
+ 321 polymyxins [chemical/ingredient]
322
+ 322 dihydrofolate reductase inhibitor antibacterial [epc]
323
+ 323 dihydrofolate reductase inhibitors [moa]
324
+ 324 organic cation transporter 2 inhibitors [moa]
325
+ 325 decreased protein synthesis [pe]
326
+ 326 decreased histamine release [pe]
327
+ 327 mast cell stabilizer [epc]
328
+ 328 adrenergic alpha-agonists [moa]
329
+ 329 alpha-adrenergic agonist [epc]
330
+ 330 adrenergic agonists [moa]
331
+ 331 adrenergic receptor agonist [epc]
332
+ 332 histamine-1 receptor inhibitor [epc]
333
+ 333 ergocalciferols [chemical/ingredient]
334
+ 334 provitamin d2 compound [epc]
335
+ 335 platinum-based drug [epc]
336
+ 336 platinum-containing compounds [chemical/ingredient]
337
+ 337 antiseptic [epc]
338
+ 338 antirheumatic agent [epc]
339
+ 339 antimalarial [epc]
340
+ 340 iron [chemical/ingredient]
341
+ 341 parenteral iron replacement [epc]
342
+ 342 phosphate binder [epc]
343
+ 343 phosphate chelating activity [moa]
344
+ 344 gamma-aminobutyric acid-ergic agonist [epc]
345
+ 345 gaba a agonists [moa]
346
+ 346 pyridines [chemical/ingredient]
347
+ 347 central nervous system depression [pe]
348
+ 348 aminoketone [epc]
349
+ 349 dopamine uptake inhibitors [moa]
350
+ 350 increased dopamine activity [pe]
351
+ 351 increased norepinephrine activity [pe]
352
+ 352 granulocyte colony-stimulating factor [chemical/ingredient]
353
+ 353 granulocyte-macrophage colony-stimulating factor [chemical/ingredient]
354
+ 354 increased myeloid cell production [pe]
355
+ 355 leukocyte growth factor [epc]
356
+ 356 hematopoietic stem cell mobilizer [epc]
357
+ 357 increased hematopoietic stem cell mobilization [pe]
358
+ 358 pcsk9 inhibitor [epc]
359
+ 359 pcsk9 inhibitors [moa]
360
+ 360 interleukin 6 receptor antagonists [moa]
361
+ 361 interleukin-6 receptor antagonist [epc]
362
+ 362 antidiarrheal [epc]
363
+ 363 anticholinergic [epc]
364
+ 364 cholinergic antagonists [moa]
365
+ 365 gonadotropin releasing hormone receptor agonist [epc]
366
+ 366 gonadotropin releasing hormone receptor agonists [moa]
367
+ 367 aldosterone antagonist [epc]
368
+ 368 aldosterone antagonists [moa]
369
+ 369 prostaglandin e1 analog [epc]
370
+ 370 prostaglandins e
371
+ 371 synthetic [chemical/ingredient]
372
+ 372 calcium channel antagonists [moa]
373
+ 373 calcium channel blocker [epc]
374
+ 374 rna synthetase inhibitor antibacterial [epc]
375
+ 375 rna synthetase inhibitors [moa]
376
+ 376 progesterone [chemical/ingredient]
377
+ 377 progesterone [epc]
378
+ 378 vitamin b6 analog [epc]
379
+ 379 vitamin b 6 [chemical/ingredient]
380
+ 380 analogs/derivatives [chemical/ingredient]
381
+ 381 vitamin b 12 [chemical/ingredient]
382
+ 382 vitamin b12 [epc]
383
+ 383 blood coagulation factor [epc]
384
+ 384 increased coagulation factor activity [pe]
385
+ 385 calcium [chemical/ingredient]
386
+ 386 cations
387
+ 387 divalent [chemical/ingredient]
388
+ 388 anti-epileptic agent [epc]
389
+ 389 decreased central nervous system disorganized electrical activity [pe]
390
+ 390 cannabinoid [epc]
391
+ 391 cannabinoids [chemical/ingredient]
392
+ 392 centrally-mediated muscle relaxation [pe]
393
+ 393 muscle relaxant [epc]
394
+ 394 increased diuresis at loop of henle [pe]
395
+ 395 loop diuretic [epc]
396
+ 396 calcium [epc]
397
+ 397 oxidation-reduction agent [epc]
398
+ 398 oxidation-reduction activity [moa]
399
+ 399 stimulation large intestine fluid/electrolyte secretion [pe]
400
+ 400 potassium compounds [chemical/ingredient]
401
+ 401 potassium salt [epc]
402
+ 402 penicillin-class antibacterial [epc]
403
+ 403 penicillins [chemical/ingredient]
404
+ 404 beta lactamase inhibitors [moa]
405
+ 405 beta lactamase inhibitor [epc]
406
+ 406 antiemetic [epc]
407
+ 407 emesis suppression [pe]
408
+ 408 azole antifungal [epc]
409
+ 409 azoles [chemical/ingredient]
410
+ 410 cytochrome p450 2c19 inhibitors [moa]
411
+ 411 cytochrome p450 2c9 inhibitors [moa]
412
+ 412 decreased gnrh secretion [pe]
413
+ 413 gonadotropin releasing hormone antagonist [epc]
414
+ 414 gonadotropin releasing hormone receptor antagonists [moa]
415
+ 415 gonadotropin [epc]
416
+ 416 gonadotropins [chemical/ingredient]
417
+ 417 neuromuscular nondepolarizing blockade [pe]
418
+ 418 nondepolarizing neuromuscular blocker [epc]
419
+ 419 live attenuated bacillus calmette-guerin vaccine [epc]
420
+ 420 bcg vaccine [chemical/ingredient]
421
+ 421 live attenuated bacillus calmette-guerin immunotherapy [epc]
422
+ 422 increased macrophage proliferation [pe]
423
+ 423 increased immunologically active molecule activity [pe]
424
+ 424 factor viii activator [epc]
425
+ 425 increased coagulation factor viii activity [pe]
426
+ 426 increased coagulation factor viii concentration [pe]
427
+ 427 vasopressin analog [epc]
428
+ 428 vasopressins [chemical/ingredient]
429
+ 429 human serum albumin [epc]
430
+ 430 increased intravascular volume [pe]
431
+ 431 increased oncotic pressure [pe]
432
+ 432 serum albumin [chemical/ingredient]
433
+ 433 cholecalciferol [chemical/ingredient]
434
+ 434 vitamin d3 analog [epc]
435
+ 435 mood stabilizer [epc]
436
+ 436 phosphodiesterase 3 inhibitor [epc]
437
+ 437 phosphodiesterase 3 inhibitors [moa]
438
+ 438 macrolide antimicrobial [epc]
439
+ 439 macrolides [chemical/ingredient]
440
+ 440 cardiac glycoside [epc]
441
+ 441 cardiac glycosides [chemical/ingredient]
442
+ 442 serotonin 3 receptor antagonists [moa]
443
+ 443 serotonin-3 receptor antagonist [epc]
444
+ 444 gamma-aminobutyric acid a receptor agonist [epc]
445
+ 445 cholinesterase inhibitor [epc]
446
+ 446 cholinesterase inhibitors [moa]
447
+ 447 dihydropyridine calcium channel blocker [epc]
448
+ 448 dihydropyridines [chemical/ingredient]
449
+ 449 herpes simplex virus nucleoside analog dna polymerase inhibitor [epc]
450
+ 450 herpes zoster virus nucleoside analog dna polymerase inhibitor [epc]
451
+ 451 herpesvirus nucleoside analog dna polymerase inhibitor [epc]
452
+ 452 partial opioid agonist [epc]
453
+ 453 partial opioid agonists [moa]
454
+ 454 opioid antagonist [epc]
455
+ 455 opioid antagonists [moa]
456
+ 456 tricyclic antidepressant [epc]
457
+ 457 cholinergic muscarinic agonists [moa]
458
+ 458 cholinergic receptor agonist [epc]
459
+ 459 vitamin d2 analog [epc]
460
+ 460 acetyl aldehyde dehydrogenase inhibitors [moa]
461
+ 461 aldehyde dehydrogenase inhibitor [epc]
462
+ 462 amphetamine anorectic [epc]
463
+ 463 amphetamines [chemical/ingredient]
464
+ 464 appetite suppression [pe]
465
+ 465 human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitor [epc]
466
+ 466 non-nucleoside analog [chemical/ingredient]
467
+ 467 non-nucleoside reverse transcriptase inhibitors [moa]
468
+ 468 cytochrome p450 3a inducers [moa]
469
+ 469 cytochrome p450 2b6 inducers [moa]
470
+ 470 amide local anesthetic [epc]
471
+ 471 amides [chemical/ingredient]
472
+ 472 local anesthesia [pe]
473
+ 473 competitive opioid antagonists [moa]
474
+ 474 opioid agonist/antagonist [epc]
475
+ 475 acidifying activity [moa]
476
+ 476 folate analog [epc]
477
+ 477 folic acid [chemical/ingredient]
478
+ 478 vitamin k antagonist [epc]
479
+ 479 vitamin k inhibitors [moa]
480
+ 480 cholinergic agonists [moa]
481
+ 481 diagnostic dye [epc]
482
+ 482 dyes [moa]
483
+ 483 alpha-1 adrenergic agonist [epc]
484
+ 484 adrenergic alpha1-agonists [moa]
485
+ 485 polyene antimicrobial [epc]
486
+ 486 polyenes [chemical/ingredient]
487
+ 487 ester local anesthetic [epc]
488
+ 488 esters [chemical/ingredient]
489
+ 489 calculi dissolution agent [epc]
490
+ 490 magnesium ion exchange activity [moa]
491
+ 491 inhibition small intestine fluid/electrolyte absorption [pe]
492
+ 492 rifamycin antibacterial [epc]
493
+ 493 general anesthesia [pe]
494
+ 494 general anesthetic [epc]
495
+ 495 heparin [chemical/ingredient]
496
+ 496 unfractionated heparin [epc]
497
+ 497 microtubule inhibition [pe]
498
+ 498 microtubule inhibitor [epc]
499
+ 499 purine antimetabolite [epc]
500
+ 500 benzodiazepine antagonist [epc]
501
+ 501 hydrolytic lysosomal glucocerebroside-specific enzyme [epc]
502
+ 502 glucosylceramidase [chemical/ingredient]
503
+ 503 typical antipsychotic [epc]
504
+ 504 histamine h2 receptor antagonists [moa]
505
+ 505 histamine-2 receptor antagonist [epc]
506
+ 506 decreased tracheobronchial stretch receptor activity [pe]
507
+ 507 non-narcotic antitussive [epc]
508
+ 508 receptor tyrosine kinase inhibitors [moa]
509
+ 509 kinase inhibitors [moa]
510
+ 510 heparin
511
+ 511 low-molecular-weight [chemical/ingredient]
512
+ 512 low molecular weight heparin [epc]
513
+ 513 partial cholinergic nicotinic agonist [epc]
514
+ 514 partial cholinergic nicotinic agonists [moa]
515
+ 515 janus kinase inhibitor [epc]
516
+ 516 janus kinase inhibitors [moa]
517
+ 517 ccr5 co-receptor antagonist [epc]
518
+ 518 chemokine co-receptor 5 antagonists [moa]
519
+ 519 glycopeptide antibacterial [epc]
520
+ 520 glycopeptides [chemical/ingredient]
521
+ 521 antihistamine [epc]
522
+ 522 histamine receptor antagonists [moa]
523
+ 523 cytochrome p450 1a2 inducers [moa]
524
+ 524 cytochrome p450 2c8 inducers [moa]
525
+ 525 cytochrome p450 2c19 inducers [moa]
526
+ 526 cytochrome p450 2d6 inducers [moa]
527
+ 527 cytochrome p450 2b6 inhibitors [moa]
528
+ 528 organic cation transporter 1 inhibitors [moa]
529
+ 529 monoamine oxidase inhibitor [epc]
530
+ 530 monoamine oxidase inhibitors [moa]
531
+ 531 nitrate vasodilator [epc]
532
+ 532 nitrates [chemical/ingredient]
533
+ 533 vasodilation [pe]
534
+ 534 peroxisome proliferator receptor alpha agonist [epc]
535
+ 535 peroxisome proliferator-activated receptor alpha agonists [moa]
536
+ 536 ppar alpha [chemical/ingredient]
537
+ 537 interleukin 2 receptor antagonists [moa]
538
+ 538 interleukin 2 receptor-directed antibody interactions [moa]
539
+ 539 interleukin-2 receptor blocking antibody [epc]
540
+ 540 udp glucuronosyltransferases inducers [moa]
541
+ 541 bcl-2 inhibitor [epc]
542
+ 542 increased cellular death [pe]
543
+ 543 alveolar surface tension reduction [pe]
544
+ 544 surfactant [epc]
545
+ 545 surfactant activity [moa]
546
+ 546 nicotinic acid [epc]
547
+ 547 nicotinic acids [chemical/ingredient]
548
+ 548 l-thyroxine [epc]
549
+ 549 thyroxine [chemical/ingredient]
550
+ 550 benzothiazole [epc]
551
+ 551 benzothiazoles [chemical/ingredient]
552
+ 552 ammonium ion binding activity [moa]
553
+ 553 nitrogen binding agent [epc]
554
+ 554 allylamine [chemical/ingredient]
555
+ 555 allylamine antifungal [epc]
556
+ 556 somatostatin analog [epc]
557
+ 557 somatostatin receptor agonists [moa]
558
+ 558 catechol o-methyltransferase inhibitors [moa]
559
+ 559 catechol-o-methyltransferase inhibitor [epc]
560
+ 560 glinide [epc]
561
+ 561 potassium channel antagonists [moa]
562
+ 562 decreased blood pressure [pe]
563
+ 563 iron chelating activity [moa]
564
+ 564 iron chelator [epc]
565
+ 565 cytochrome p450 1a2 inhibitors [moa]
566
+ 566 renin inhibitor [epc]
567
+ 567 renin inhibitors [moa]
568
+ 568 sphingosine 1-phosphate receptor modulators [moa]
569
+ 569 sphingosine 1-phosphate receptor modulator [epc]
570
+ 570 adrenergic beta2-agonists [moa]
571
+ 571 beta2-adrenergic agonist [epc]
572
+ 572 tyrosine kinase inhibitors [moa]
573
+ 573 hedgehog pathway inhibitor [epc]
574
+ 574 smoothened receptor antagonists [moa]
575
+ 575 neprilysin inhibitor [epc]
576
+ 576 neprilysin inhibitors [moa]
577
+ 577 cd20-directed cytolytic antibody [epc]
578
+ 578 cd20-directed antibody interactions [moa]
579
+ 579 organic anion transporter 1 inhibitors [moa]
580
+ 580 organic anion transporter 3 inhibitors [moa]
581
+ 581 cytochrome p450 3a5 inhibitors [moa]
582
+ 582 acetylcholine releasing agent [epc]
583
+ 583 increased acetylcholine activity [pe]
584
+ 584 interferon alfa-2b [chemical/ingredient]
585
+ 585 interferon-alpha [chemical/ingredient]
586
+ 586 androgen receptor antagonists [moa]
587
+ 587 androgen receptor inhibitor [epc]
588
+ 588 polyene antifungal [epc]
589
+ 589 cardiac rhythm alteration [pe]
590
+ 590 cephalosporin antibacterial [epc]
591
+ 591 cephalosporins [chemical/ingredient]
592
+ 592 peroxisome proliferator receptor gamma agonist [epc]
593
+ 593 peroxisome proliferator-activated receptor activity [moa]
594
+ 594 ppar gamma [chemical/ingredient]
595
+ 595 thiazolidinedione [epc]
596
+ 596 thiazolidinediones [chemical/ingredient]
597
+ 597 sympathomimetic amine anorectic [epc]
598
+ 598 nitrofuran antibacterial [epc]
599
+ 599 nitrofurans [chemical/ingredient]
600
+ 600 dopamine d2 antagonists [moa]
601
+ 601 dopamine-2 receptor antagonist [epc]
602
+ 602 aluminum complex [epc]
603
+ 603 organometallic compounds [chemical/ingredient]
604
+ 604 adrenergic alpha2-agonists [moa]
605
+ 605 central alpha-2 adrenergic agonist [epc]
606
+ 606 tetracycline-class drug [epc]
607
+ 607 blood viscosity reducer [epc]
608
+ 608 hematologic activity alteration [pe]
609
+ 609 fatty acids
610
+ 610 omega-3 [chemical/ingredient]
611
+ 611 omega-3 fatty acid [epc]
612
+ 612 ergolines [chemical/ingredient]
613
+ 613 ergot derivative [epc]
614
+ 614 inhibition gastric acid secretion [pe]
615
+ 615 phenothiazine [epc]
616
+ 616 phenothiazines [chemical/ingredient]
617
+ 617 decreased cholesterol absorption [pe]
618
+ 618 dietary cholesterol absorption inhibitor [epc]
619
+ 619 vitamin d analog [epc]
620
+ 620 bile acid [epc]
621
+ 621 bile acids and salts [chemical/ingredient]
622
+ 622 adrenergic beta-agonists [moa]
623
+ 623 beta-adrenergic agonist [epc]
624
+ 624 catecholamine [epc]
625
+ 625 catecholamines [chemical/ingredient]
626
+ 626 influenza a m2 protein inhibitor [epc]
627
+ 627 m2 protein inhibitors [moa]
628
+ 628 decreased striated muscle contraction [pe]
629
+ 629 decreased striated muscle tone [pe]
630
+ 630 skeletal muscle relaxant [epc]
631
+ 631 decreased cell wall integrity [pe]
632
+ 632 decreased coagulation factor activity [pe]
633
+ 633 calcium chelating activity [moa]
634
+ 634 sulfonamide antimicrobial [epc]
635
+ 635 thyroid hormone synthesis inhibitor [epc]
636
+ 636 thyroid hormone synthesis inhibitors [moa]
637
+ 637 ergotamine derivative [epc]
638
+ 638 ergotamines [chemical/ingredient]
639
+ 639 p-glycoprotein interactions [moa]
640
+ 640 xanthine oxidase inhibitor [epc]
641
+ 641 xanthine oxidase inhibitors [moa]
642
+ 642 purines [chemical/ingredient]
643
+ 643 increased uterine smooth muscle contraction or tone [pe]
644
+ 644 oxytocic [epc]
645
+ 645 oxytocin [chemical/ingredient]
646
+ 646 sympathomimetic-like agent [epc]
647
+ 647 macrolide [epc]
648
+ 648 decreased dna replication [pe]
649
+ 649 decreased rna replication [pe]
650
+ 650 protein synthesis inhibitors [moa]
651
+ 651 increased cytokine activity [pe]
652
+ 652 increased cytokine production [pe]
653
+ 653 interferon inducers [moa]
654
+ 654 recombinant human growth hormone [epc]
655
+ 655 recombinant human growth hormones [chemical/ingredient]
656
+ 656 gaba b agonists [moa]
657
+ 657 decreased platelet production [pe]
658
+ 658 platelet-reducing agent [epc]
659
+ 659 prostacycline vasodilator [epc]
660
+ 660 prostaglandins i [chemical/ingredient]
661
+ 661 neuraminidase inhibitor [epc]
662
+ 662 neuraminidase inhibitors [moa]
663
+ 663 potassium channel openers [moa]
664
+ 664 potassium channel opener [epc]
665
+ 665 interleukin-5 antagonist [epc]
666
+ 666 interleukin-5 antagonists [moa]
667
+ 667 urease inhibitor [epc]
668
+ 668 urease inhibitors [moa]
669
+ 669 cystine disulfide reduction [moa]
670
+ 670 n-substituted glycines [chemical/ingredient]
671
+ 671 reducing and complexing thiol [epc]
672
+ 672 thiazide-like diuretic [epc]
673
+ 673 l-triiodothyronine [epc]
674
+ 674 triiodothyronine [chemical/ingredient]
675
+ 675 dihydrofolate reductase inhibitor antimalarial [epc]
676
+ 676 increased prothrombin activity [pe]
677
+ 677 reversed anticoagulation activity [pe]
678
+ 678 vitamin k [chemical/ingredient]
679
+ 679 vitamin k [epc]
680
+ 680 warfarin reversal agent [epc]
681
+ 681 phenylalanine hydroxylase activators [moa]
682
+ 682 interleukin-17 receptor a antagonist [epc]
683
+ 683 interleukin 17 receptor a antagonists [moa]
684
+ 684 monoamine oxidase type b inhibitor [epc]
685
+ 685 monoamine oxidase-b inhibitors [moa]
686
+ 686 photoabsorption [moa]
687
+ 687 photoactivated radical generator [epc]
688
+ 688 photosensitizing activity [pe]
689
+ 689 psoralen [epc]
690
+ 690 psoralens [chemical/ingredient]
691
+ 691 metal chelating activity [moa]
692
+ 692 metal chelator [epc]
693
+ 693 nucleoside analog antifungal [epc]
694
+ 694 decreased parasympathetic acetylcholine activity [pe]
695
+ 695 gi motility alteration [pe]
696
+ 696 digestive/gi system activity alteration [pe]
697
+ 697 vasodilator [epc]
698
+ 698 photoenhancer [epc]
699
+ 699 calcitonin [chemical/ingredient]
700
+ 700 calcitonin [epc]
701
+ 701 non-standardized plant allergenic extract [epc]
702
+ 702 non-standardized food allergenic extract [epc]
703
+ 703 dietary proteins [chemical/ingredient]
704
+ 704 plant proteins [chemical/ingredient]
705
+ 705 food additives [chemical/ingredient]
706
+ 706 non-standardized chemical allergen [epc]
707
+ 707 glycerol [chemical/ingredient]
708
+ 708 amino acid [epc]
709
+ 709 amino acids [chemical/ingredient]
710
+ 710 plasma volume expander [epc]
711
+ 711 starch [chemical/ingredient]
712
+ 712 osmotic diuretic [epc]
713
+ 713 lipid emulsion [epc]
714
+ 714 lipids [chemical/ingredient]
715
+ 715 non-standardized pollen allergenic extract [epc]
716
+ 716 standardized animal skin allergenic extract [epc]
717
+ 717 fur [chemical/ingredient]
718
+ 718 standardized insect allergenic extract [epc]
719
+ 719 antigens
720
+ 720 dermatophagoides [chemical/ingredient]
721
+ 721 insect proteins [chemical/ingredient]
722
+ 722 non-standardized animal skin allergenic extract [epc]
723
+ 723 cells
724
+ 724 epidermal [chemical/ingredient]
725
+ 725 non-standardized plant fiber allergenic extract [epc]
726
+ 726 seed storage proteins [chemical/ingredient]
727
+ 727 meat proteins [chemical/ingredient]
728
+ 728 non-standardized insect allergenic extract [epc]
729
+ 729 non-standardized insect venom allergenic extract [epc]
730
+ 730 ant venoms [chemical/ingredient]
731
+ 731 non-standardized feather allergenic extract [epc]
732
+ 732 feathers [chemical/ingredient]
733
+ 733 non-standardized fungal allergenic extract [epc]
734
+ 734 fungal proteins [chemical/ingredient]
735
+ 735 standardized animal hair allergenic extract [epc]
736
+ 736 dander [chemical/ingredient]
737
+ 737 salivary proteins and peptides [chemical/ingredient]
738
+ 738 non-standardized house dust allergenic extract [epc]
739
+ 739 house dust [chemical/ingredient]
740
+ 740 nut proteins [chemical/ingredient]
741
+ 741 fruit proteins [chemical/ingredient]
742
+ 742 vegetable proteins [chemical/ingredient]
743
+ 743 grain proteins [chemical/ingredient]
744
+ 744 caseins [chemical/ingredient]
745
+ 745 poultry proteins [chemical/ingredient]
746
+ 746 shellfish proteins [chemical/ingredient]
747
+ 747 fish proteins
748
+ 748 dietary [chemical/ingredient]
749
+ 749 egg proteins
750
+ 750 milk proteins [chemical/ingredient]
751
+ 751 radiopharmaceutical activity [moa]
752
+ 752 cholecystokinin [chemical/ingredient]
753
+ 753 cholecystokinin analog [epc]
754
+ 754 paramagnetic contrast agent [epc]
755
+ 755 digoxin binding activity [moa]
756
+ 756 depigmenting activity [pe]
757
+ 757 melanin synthesis inhibitor [epc]
758
+ 758 melanin synthesis inhibitors [moa]
759
+ 759 phosphodiesterase 4 inhibitor [epc]
760
+ 760 phosphodiesterase 4 inhibitors [moa]
761
+ 761 poly(adp-ribose) polymerase inhibitor [epc]
762
+ 762 poly(adp-ribose) polymerase inhibitors [moa]
763
+ 763 estrogen receptor antagonist [epc]
764
+ 764 estrogen receptor antagonists [moa]
765
+ 765 urate transporter 1 inhibitor [epc]
766
+ 766 urate transporter 1 inhibitors [moa]
767
+ 767 sodium-glucose cotransporter 2 inhibitor [epc]
768
+ 768 sodium-glucose transporter 2 inhibitors [moa]
769
+ 769 amylin agonists [moa]
770
+ 770 amylin analog [epc]
771
+ 771 standardized chemical allergen [epc]
772
+ 772 irrigation [moa]
773
+ 773 human blood coagulation factor [epc]
774
+ 774 increased coagulation activity [pe]
775
+ 775 blood coagulation factors [chemical/ingredient]
776
+ 776 nmda receptor antagonists [moa]
777
+ 777 n-methyl-d-aspartate receptor antagonist [epc]
778
+ 778 p-glycoprotein inducers [moa]
779
+ 779 benzylamine antifungal [epc]
780
+ 780 benzylamines [chemical/ingredient]
781
+ 781 cystine depleting agent [epc]
782
+ 782 local anesthetic [epc]
783
+ 783 contrast agent for ultrasound imaging [epc]
784
+ 784 ultrasound contrast activity [moa]
785
+ 785 lipopeptide antibacterial [epc]
786
+ 786 adenosine receptor agonist [epc]
787
+ 787 adenosine receptor agonists [moa]
788
+ 788 partial opioid agonist/antagonist [epc]
789
+ 789 dopaminergic agonist [epc]
790
+ 790 antidote [epc]
791
+ 791 antidote for acetaminophen overdose [epc]
792
+ 792 decreased respiratory secretion viscosity [pe]
793
+ 793 increased glutathione concentration [pe]
794
+ 794 mucolytic [epc]
795
+ 795 reduction activity [moa]
796
+ 796 copper absorption inhibitor [epc]
797
+ 797 decreased copper ion absorption [pe]
798
+ 798 depolarizing neuromuscular blocker [epc]
799
+ 799 neuromuscular depolarizing blockade [pe]
800
+ 800 tetracycline-class antimicrobial [epc]
801
+ 801 guanylate cyclase-c agonist [epc]
802
+ 802 guanylate cyclase activators [moa]
803
+ 803 beta3-adrenergic agonist [epc]
804
+ 804 adrenergic beta3-agonists [moa]
805
+ 805 lipid-based polyene antifungal [epc]
806
+ 806 decreased mitosis [pe]
807
+ 807 tubulin inhibiting agent [epc]
808
+ 808 pyrethrins [chemical/ingredient]
809
+ 809 pyrethroid [epc]
810
+ 810 arteriolar vasodilation [pe]
811
+ 811 arteriolar vasodilator [epc]
812
+ 812 carnitine [chemical/ingredient]
813
+ 813 carnitine analog [epc]
814
+ 814 cholinergic muscarinic agonist [epc]
815
+ 815 adrenocorticotropic hormone [chemical/ingredient]
816
+ 816 adrenocorticotropic hormone [epc]
817
+ 817 endoglycosidase [epc]
818
+ 818 glycoside hydrolases [chemical/ingredient]
819
+ 819 human immunoglobulin g [epc]
820
+ 820 passively acquired immunity [pe]
821
+ 821 endogenous antigen neutralization [moa]
822
+ 822 uncompetitive n-methyl-d-aspartate receptor antagonist [epc]
823
+ 823 sigma-1 agonist [epc]
824
+ 824 uncompetitive nmda receptor antagonists [moa]
825
+ 825 sigma-1 receptor agonists [moa]
826
+ 826 antihypoglycemic agent [epc]
827
+ 827 gastrointestinal motility inhibitor [epc]
828
+ 828 increased gluconeogenesis [pe]
829
+ 829 increased glycogenolysis [pe]
830
+ 830 decreased gi smooth muscle tone [pe]
831
+ 831 decreased gi motility [pe]
832
+ 832 decreased glycolysis [pe]
833
+ 833 humanized monoclonal antibody fragment [epc]
834
+ 834 monoclonal
835
+ 835 humanized [chemical/ingredient]
836
+ 836 vitamin a [chemical/ingredient]
837
+ 837 vitamin a [epc]
838
+ 838 increased medullary respiratory drive [pe]
839
+ 839 respiratory stimulant [epc]
840
+ 840 copper [chemical/ingredient]
841
+ 841 copper-containing intrauterine device [epc]
842
+ 842 decreased embryonic implantation [pe]
843
+ 843 decreased sperm motility [pe]
844
+ 844 autonomic ganglionic blocker [epc]
845
+ 845 decreased autonomic ganglionic activity [pe]
846
+ 846 antigen neutralization [moa]
847
+ 847 human alpha-1 proteinase inhibitor [epc]
848
+ 848 trypsin inhibitors [moa]
849
+ 849 asparaginase [chemical/ingredient]
850
+ 850 asparagine-specific enzyme [epc]
851
+ 851 5-lipoxygenase inhibitor [epc]
852
+ 852 5-lipoxygenase inhibitors [moa]
853
+ 853 decreased leukotriene production [pe]
854
+ 854 potassium channel blocker [epc]
855
+ 855 glucosylceramide synthase inhibitor [epc]
856
+ 856 glucosylceramide synthase inhibitors [moa]
857
+ 857 oxaborole antifungal [epc]
858
+ 858 boron compounds [chemical/ingredient]
859
+ 859 cholinesterase reactivator [epc]
860
+ 860 cholinesterase reactivators [moa]
861
+ 861 inhalation diagnostic agent [epc]
862
+ 862 inactivated clostridium tetani vaccine [epc]
863
+ 863 tetanus toxoid [chemical/ingredient]
864
+ 864 inactivated corynebacterium diphtheriae vaccine [epc]
865
+ 865 diphtheria toxoid [chemical/ingredient]
866
+ 866 human immunoglobulin [epc]
867
+ 867 virus neutralization [moa]
868
+ 868 virus-specific hyperimmune globulins [chemical/ingredient]
869
+ 869 norepinephrine releasing agent [epc]
870
+ 870 pleuromutilin [chemical/ingredient]
871
+ 871 pleuromutilin antibacterial [epc]
872
+ 872 chloride channel activator [epc]
873
+ 873 chloride channel activators [moa]
874
+ 874 bee venoms [chemical/ingredient]
875
+ 875 standardized insect venom allergenic extract [epc]
876
+ 876 radioactive therapeutic agent [epc]
877
+ 877 increased prostaglandin activity [pe]
878
+ 878 n-calcium channel receptor antagonists [moa]
879
+ 879 n-type calcium channel antagonist [epc]
880
+ 880 melatonin receptor agonist [epc]
881
+ 881 melatonin receptor agonists [moa]
882
+ 882 demulcent [epc]
883
+ 883 demulcent activity [moa]
884
+ 884 proteolytic enzyme [epc]
885
+ 885 peptide hydrolases [chemical/ingredient]
886
+ 886 catecholamine synthesis inhibitor [epc]
887
+ 887 catecholamine synthesis inhibitors [moa]
888
+ 888 complement inhibitor [epc]
889
+ 889 complement inhibitors [moa]
890
+ 890 hydrolytic lysosomal cholesteryl ester-specific enzyme [epc]
891
+ 891 hydrolytic lysosomal triacylglycerol-specific enzyme [epc]
892
+ 892 lysosomal acid cholesterol esterase [chemical/ingredient]
893
+ 893 tissue-nonspecific alkaline phosphatase [epc]
894
+ 894 alkaline phosphatase [chemical/ingredient]
895
+ 895 autologous cellular immunotherapy [epc]
896
+ 896 cultured
897
+ 897 autologous [chemical/ingredient]
898
+ 898 peripheral blood mononuclear cells [chemical/ingredient]
899
+ 899 vesicular monoamine transporter 2 inhibitor [epc]
900
+ 900 vesicular monoamine transporter 2 inhibitors [moa]
901
+ 901 inactivated influenza a virus vaccine [epc]
902
+ 902 influenza vaccines [chemical/ingredient]
903
+ 903 silk [chemical/ingredient]
904
+ 904 skin test antigen [epc]
905
+ 905 tuberculosis skin test [epc]
906
+ 906 bacterial [chemical/ingredient]
907
+ 907 human c1 esterase inhibitor [epc]
908
+ 908 decreased vascular permeability [pe]
909
+ 909 kallikrein inhibitors [moa]
910
+ 910 interferon gamma [epc]
911
+ 911 interferon-gamma [chemical/ingredient]
912
+ 912 inactivated japanese encephalitis virus vaccine [epc]
913
+ 913 japanese encephalitis vaccines [chemical/ingredient]
914
+ 914 allogeneic cultured cell scaffold [epc]
915
+ 915 collagen [chemical/ingredient]
916
+ 916 tissue scaffolds [chemical/ingredient]
917
+ 917 allogeneic [chemical/ingredient]
918
+ 918 fibroblasts [chemical/ingredient]
919
+ 919 keratinocytes [chemical/ingredient]
920
+ 920 recombinant antithrombin [epc]
921
+ 921 anti-anginal [epc]
922
+ 922 live attenuated influenza a virus vaccine [epc]
923
+ 923 interferon-beta [chemical/ingredient]
924
+ 924 recombinant human interferon beta [epc]
925
+ 925 recombinant proteins [chemical/ingredient]
926
+ 926 parathyroid hormone [epc]
927
+ 927 sclerosing agent [epc]
928
+ 928 sclerosing activity [moa]
929
+ 929 vascular sclerosing activity [pe]
930
+ 930 plasma kallikrein inhibitor [epc]
931
+ 931 inactivated bordetella pertussis vaccine [epc]
932
+ 932 pertussis vaccine [chemical/ingredient]
933
+ 933 inactivated poliovirus vaccine [epc]
934
+ 934 poliovirus vaccine [chemical/ingredient]
935
+ 935 inactivated meningococcal vaccine [epc]
936
+ 936 meningococcal vaccines [chemical/ingredient]
937
+ 937 inactivated salmonella typhi vaccine [epc]
938
+ 938 typhoid [chemical/ingredient]
939
+ 939 vi polysaccharide vaccine
940
+ 940 live attenuated yellow fever virus vaccine [epc]
941
+ 941 yellow fever vaccine [chemical/ingredient]
942
+ 942 non-standardized bacterial allergenic extract [epc]
943
+ 943 bacterial proteins [chemical/ingredient]
944
+ 944 non-standardized animal hair allergenic extract [epc]
945
+ 945 decreased b lymphocyte activation [pe]
946
+ 946 b lymphocyte stimulator-specific inhibitor [epc]
947
+ 947 b lymphocyte stimulator-directed antibody interactions [moa]
948
+ 948 anthrax protective antigen-directed antibody [epc]
949
+ 949 anthrax protective antigen-directed antibody interactions [moa]
950
+ 950 multidrug and toxin extrusion transporter 1 inhibitors [moa]
951
+ 951 methylated sulfonamide antibacterial [epc]
952
+ 952 methylated sulfonamides [chemical/ingredient]
953
+ 953 selective progesterone receptor modulators [moa]
954
+ 954 progesterone agonist/antagonist [epc]
955
+ 955 live vaccinia virus vaccine [epc]
956
+ 956 smallpox vaccine [chemical/ingredient]
957
+ 957 cell death inducer [epc]
958
+ 958 anti-ige [epc]
959
+ 959 decreased ige activity [pe]
960
+ 960 ige-directed antibody interactions [moa]
961
+ 961 vascular endothelial growth factor receptor inhibitors [moa]
962
+ 962 vascular endothelial growth factor-directed antibody [epc]
963
+ 963 vascular endothelial growth factor-directed antibody interactions [moa]
964
+ 964 deoxyribonuclease i [chemical/ingredient]
965
+ 965 recombinant human deoxyribonuclease 1 [epc]
966
+ 966 pyridone [epc]
967
+ 967 pyridones [chemical/ingredient]
968
+ 968 her2 receptor antagonist [epc]
969
+ 969 her2/neu/cerbb2 antagonists [moa]
970
+ 970 antibodies [chemical/ingredient]
971
+ 971 radioactive alpha-particle emitting therapeutic agent [epc]
972
+ 972 alpha-particle emitting activity [moa]
973
+ 973 guanylate cyclase stimulators [moa]
974
+ 974 soluble guanylate cyclase stimulator [epc]
975
+ 975 antihelminthic [epc]
976
+ 976 glycosaminoglycan [epc]
977
+ 977 glycosaminoglycans [chemical/ingredient]
978
+ 978 epoxide hydrolase inhibitors [moa]
979
+ 979 collagenases [chemical/ingredient]
980
+ 980 collagen-specific enzyme [epc]
981
+ 981 human platelet-derived growth factor [epc]
982
+ 982 platelet-derived growth factor [chemical/ingredient]
983
+ 983 antivenin [epc]
984
+ 984 venom neutralization [moa]
985
+ 985 antivenins [chemical/ingredient]
986
+ 986 carboxypeptidase [epc]
987
+ 987 carboxypeptidases [chemical/ingredient]
988
+ 988 cd30-directed antibody interactions [moa]
989
+ 989 cd30-directed immunoconjugate [epc]
990
+ 990 immunoconjugates [chemical/ingredient]
991
+ 991 cystic fibrosis transmembrane conductance regulator potentiator [epc]
992
+ 992 chloride channel activation potentiators [moa]
993
+ 993 lead chelating activity [moa]
994
+ 994 lead chelator [epc]
995
+ 995 macrolide antibacterial [epc]
996
+ 996 cytochrome p450 1a inducers [moa]
997
+ 997 lipoglycopeptide antibacterial [epc]
998
+ 998 lipoglycopeptides [chemical/ingredient]
999
+ 999 carbamoyl phosphate synthetase 1 activator [epc]
1000
+ 1000 carbamoyl phosphate synthetase 1 activators [moa]
1001
+ 1001 methylating activity [moa]
1002
+ 1002 methylating agent [epc]
1003
+ 1003 wasp venoms [chemical/ingredient]
1004
+ 1004 potassium binder [epc]
1005
+ 1005 potassium ion binding activity [moa]
1006
+ 1006 calcium-sensing receptor agonist [epc]
1007
+ 1007 increased calcium-sensing receptor sensitivity [moa]
1008
+ 1008 lymphocyte function-associated antigen-1 antagonist [epc]
1009
+ 1009 lymphocyte function-associated antigen-1 antagonists [moa]
1010
+ 1010 alpha-glucosidases [chemical/ingredient]
1011
+ 1011 hydrolytic lysosomal glycosaminoglycan-specific enzyme [epc]
1012
+ 1012 bradykinin b2 receptor antagonist [epc]
1013
+ 1013 bradykinin b2 receptor antagonists [moa]
1014
+ 1014 urate oxidase [chemical/ingredient]
1015
+ 1015 uric acid-specific enzyme [epc]
1016
+ 1016 aromatic amino acid decarboxylation inhibitor [epc]
1017
+ 1017 dopa decarboxylase inhibitors [moa]
1018
+ 1018 ketolide antibacterial [epc]
1019
+ 1019 ketolides [chemical/ingredient]
1020
+ 1020 heparin binding activity [moa]
1021
+ 1021 heparin reversal agent [epc]
1022
+ 1022 actinomycin [epc]
1023
+ 1023 free radical scavenging activity [moa]
1024
+ 1024 rank ligand inhibitor [epc]
1025
+ 1025 rank ligand blocking activity [moa]
1026
+ 1026 hyperpolarization-activated cyclic nucleotide-gated channel blocker [epc]
1027
+ 1027 hyperpolarization-activated cyclic nucleotide-gated channel antagonists [moa]
1028
+ 1028 adenosine deaminase [chemical/ingredient]
1029
+ 1029 bovine intestinal adenosine deaminase [epc]
1030
+ 1030 interleukin-12 antagonist [epc]
1031
+ 1031 interleukin-12 antagonists [moa]
1032
+ 1032 interleukin-23 antagonist [epc]
1033
+ 1033 interleukin-23 antagonists [moa]
1034
+ 1034 cytochrome p450 17a1 inhibitors [moa]
1035
+ 1035 cytochrome p450 17a1 inhibitor [epc]
1036
+ 1036 interleukin-6 antagonist [epc]
1037
+ 1037 interleukin-6 antagonists [moa]
1038
+ 1038 cd38-directed cytolytic antibody [epc]
1039
+ 1039 cd38-directed antibody interactions [moa]
1040
+ 1040 decorporation agent [epc]
1041
+ 1041 ion exchange activity [moa]
1042
+ 1042 chelating activity [moa]
1043
+ 1043 thyroid stimulating hormone [epc]
1044
+ 1044 thyrotropin [chemical/ingredient]
1045
+ 1045 hydrolytic lysosomal neutral glycosphingolipid-specific enzyme [epc]
1046
+ 1046 hydrolytic lysosomal glycogen-specific enzyme [epc]
1047
+ 1047 apolipoprotein b-100 synthesis inhibitor [epc]
1048
+ 1048 antisense oligonucleotide [epc]
1049
+ 1049 oligonucleotides
1050
+ 1050 antisense [chemical/ingredient]
1051
+ 1051 cd52-directed antibody interactions [moa]
1052
+ 1052 cd52-directed cytolytic antibody [epc]
1053
+ 1053 pyrimidine synthesis inhibitor [epc]
1054
+ 1054 dihydroorotate dehydrogenase inhibitors [moa]
1055
+ 1055 autologous cultured cell [epc]
1056
+ 1056 chondrocytes [chemical/ingredient]
1057
+ 1057 bismuth [chemical/ingredient]
1058
+ 1058 bismuth [epc]
1059
+ 1059 vasopressin v2 receptor antagonist [epc]
1060
+ 1060 vasopressin v2 receptor antagonists [moa]
1061
+ 1061 decreased immunologically active molecule activity [pe]
1062
+ 1062 thalidomide analog [epc]
1063
+ 1063 fungal [chemical/ingredient]
1064
+ 1064 cd3 blocker immunosuppressant [epc]
1065
+ 1065 cd3 receptor antagonists [moa]
1066
+ 1066 cd3-directed antibody interactions [moa]
1067
+ 1067 diarylquinoline antimycobacterial [epc]
1068
+ 1068 diarylquinolines [chemical/ingredient]
1069
+ 1069 fusion protein inhibitors [moa]
1070
+ 1070 respiratory syncytial virus anti-f protein monoclonal antibody [epc]
1071
+ 1071 angiotensin 2 type 1 receptor antagonists [moa]
1072
+ 1072 cytolytic agent [epc]
1073
+ 1073 decreased cell membrane integrity [pe]
1074
+ 1074 streptogramin antibacterial [epc]
1075
+ 1075 streptogramins [chemical/ingredient]
1076
+ 1076 antileishmanial [epc]
1077
+ 1077 mu-opioid receptor agonist [epc]
1078
+ 1078 opioid mu-receptor agonists [moa]
1079
+ 1079 endothelin receptor antagonist [epc]
1080
+ 1080 endothelin receptor antagonists [moa]
1081
+ 1081 hepatitis c virus nucleotide analog ns5b polymerase inhibitor [epc]
1082
+ 1082 rna replicase inhibitors [moa]
1083
+ 1083 organic anion transporting polypeptide 2b1 inhibitors [moa]
1084
+ 1084 noncompetitive ampa glutamate receptor antagonist [epc]
1085
+ 1085 ampa receptor antagonists [moa]
1086
+ 1086 serotonin-2c receptor agonist [epc]
1087
+ 1087 serotonin 2c receptor agonists [moa]
1088
+ 1088 proteasome inhibitor [epc]
1089
+ 1089 proteasome inhibitors [moa]
1090
+ 1090 amphenicol-class antibacterial [epc]
1091
+ 1091 amphenicols [chemical/ingredient]
1092
+ 1092 deoxyuridine [chemical/ingredient]
1093
+ 1093 integrin receptor antagonist [epc]
1094
+ 1094 integrin receptor antagonists [moa]
1095
+ 1095 survival motor neuron-2-directed rna interaction [epc]
1096
+ 1096 increased protein synthesis [pe]
1097
+ 1097 live attenuated bacillus anthracis vaccine [epc]
1098
+ 1098 anthrax vaccines [chemical/ingredient]
1099
+ 1099 thymidine phosphorylase inhibitor [epc]
1100
+ 1100 thymidine phosphorylase inhibitors [moa]
1101
+ 1101 non-standardized animal dander allergenic extract [epc]
1102
+ 1102 increased lymphocyte activation [pe]
1103
+ 1103 increased lymphocyte cell production [pe]
1104
+ 1104 interleukin-2 [chemical/ingredient]
1105
+ 1105 lymphocyte growth factor [epc]
1106
+ 1106 quaternary ammonium compounds [chemical/ingredient]
1107
+ 1107 natriuretic peptide [epc]
1108
+ 1108 natriuretic peptides [chemical/ingredient]
1109
+ 1109 prostacycline [epc]
1110
+ 1110 prostacyclin receptor agonist [epc]
1111
+ 1111 prostacyclin receptor agonists [moa]
1112
+ 1112 vasopressin receptor antagonists [moa]
1113
+ 1113 vasopressin receptor antagonist [epc]
1114
+ 1114 glycolipid disialoganglioside-directed antibody [epc]
1115
+ 1115 glycolipid disialoganglioside-directed antibody interactions [moa]
1116
+ 1116 hydroxyphenyl-pyruvate dioxygenase inhibitor [epc]
1117
+ 1117 hydroxyphenylpyruvate dioxygenase inhibitors [moa]
1118
+ 1118 fibroblast growth factor 7 [chemical/ingredient]
1119
+ 1119 increased epithelial proliferation [pe]
1120
+ 1120 mucocutaneous epithelial cell growth factor [epc]
1121
+ 1121 interleukin 1 receptor antagonists [moa]
1122
+ 1122 interleukin-1 receptor antagonist [epc]
1123
+ 1123 increased blood pressure [pe]
1124
+ 1124 human antihemophilic factor [epc]
1125
+ 1125 factor viii [chemical/ingredient]
1126
+ 1126 increased platelet aggregation [pe]
1127
+ 1127 von willebrand factor [chemical/ingredient]
1128
+ 1128 sucrose-specific enzyme [epc]
1129
+ 1129 phenylalanine hydroxylase activator [epc]
1130
+ 1130 bacterial neurotoxin neutralization [moa]
1131
+ 1131 antitoxins [chemical/ingredient]
1132
+ 1132 central nervous system depressant [epc]
1133
+ 1133 decreased central nervous system organized electrical activity [pe]
1134
+ 1134 oligonucleotides [chemical/ingredient]
1135
+ 1135 aptamers
1136
+ 1136 nucleotide [chemical/ingredient]
1137
+ 1137 glp-2 analog [epc]
1138
+ 1138 glucagon-like peptide-2 (glp-2) agonists [moa]
1139
+ 1139 glucagon-like peptide 2 [chemical/ingredient]
1140
+ 1140 live attenuated salmonella typhi vaccine [epc]
1141
+ 1141 pyrimidine analog [epc]
1142
+ 1142 pyrimidines [chemical/ingredient]
1143
+ 1143 farnesoid x receptor agonist [epc]
1144
+ 1144 farnesoid x receptor agonists [moa]
1145
+ 1145 inactivated influenza b virus vaccine [epc]
1146
+ 1146 porphyrin precursor [epc]
1147
+ 1147 porphyrinogens [chemical/ingredient]
1148
+ 1148 fluoroquinolone antibacterial [epc]
1149
+ 1149 fluoroquinolones [chemical/ingredient]
1150
+ 1150 pyrophosphate analog [chemical/ingredient]
1151
+ 1151 pyrophosphate analog dna polymerase inhibitor [epc]
1152
+ 1152 adrenal steroid synthesis inhibitor [epc]
1153
+ 1153 adrenal steroid synthesis inhibitors [moa]
1154
+ 1154 progestational hormone receptor antagonists [moa]
1155
+ 1155 progestin antagonist [epc]
1156
+ 1156 microsomal triglyceride transfer protein inhibitor [epc]
1157
+ 1157 microsomal triglyceride transfer protein inhibitors [moa]
1158
+ 1158 leptin analog [epc]
1159
+ 1159 leptin [chemical/ingredient]
1160
+ 1160 allogeneic cord blood hematopoietic progenitor cell therapy [epc]
1161
+ 1161 hematopoietic stem cells [chemical/ingredient]
raw/NDC-classes-full-nverts.txt ADDED
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raw/NDC-classes-full-simplex-labels.txt ADDED
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raw/NDC-classes-full-simplices.txt ADDED
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raw/NDC-classes-full-times.txt ADDED
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raw/README.txt ADDED
@@ -0,0 +1,14 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ This dataset consists of the pharmaceutical classes used to classify drugs in
2
+ the National Drug Code Directory maintained by the Food and Drug
3
+ Administration. The original data was downloaded from
4
+ https://www.fda.gov/Drugs/InformationOnDrugs/ucm142438.htm. Each simplex
5
+ corresponds to an NDC code for a drug, where the nodes are the classes applied
6
+ to the drug. Timestamps are in days and represent when the drug was first
7
+ marketed. Note that the same drug substance can have more than one NDC code. For
8
+ example, different dosages of the same drug may result in multiple NDC codes.
9
+
10
+
11
+ The file NDC-classes-node-labels.txt maps the node IDs to the classes.
12
+
13
+ The nth line in NDC-classes-simplex-labels.txt is the name of the drug
14
+ corresponding to the nth simplex.