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taskId
int64 | title
float64 | text
string | url
string | sourceLink
string | subSourceLink
string | views
int64 | likes
int64 | createTime
int64 | crawlTime
int64 | clusterId
int64 | vector
string | ners
string | sentiment
string | language
string | spam
string | length
int64 | swearWordsCount
int64 | capslockWordsCount
int64 | ru
float64 | eng
float64 | other
float64 | adj
int64 | verb
int64 | pron
int64 | num
int64 | noun
int64 | adv
int64 | punc
int64 | markedUp
bool |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
118 | null | Модуль электромагнитной левитации
Эта простая инженерная система управления использует регулируемый электромагнит (медная катушка) и датчик магнитного поля Холла (встроенный в центр катушки) для левитации неодимового магнита и предотвращения его падения.
#интереснаяфизика | https://t.me/chemistrytg2021/9571?embed=1&mode=tme | https://t.me/ | https://t.me/s/chemistrytg2021 | 1,100 | 0 | 1,736,436,004 | 1,736,456,913 | 1,337 | 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| [{"ner":"Холла","lemma":"холл","label":"PER","start_pos":156,"end_pos":161}] | NEUTRAL | rus | NOT SPAM | 31 | 0 | 0 | 1 | 0 | 0 | 6 | 3 | 0 | 0 | 15 | 0 | 6 | true |
118 | null | Фотография анодированного титана.
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Анодирование (анодное окисление) — процесс создания оксидной плёнки на поверхности некоторых металлов путём их поляризации в проводящей среде. | https://t.me/chemistrytg2021/9572?embed=1&mode=tme | https://t.me/ | https://t.me/s/chemistrytg2021 | 721 | 0 | 1,736,446,800 | 1,736,456,913 | 1,340 | 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| null | NEUTRAL | rus | NOT SPAM | 22 | 0 | 0 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 12 | 0 | 6 | true |
118 | null | На сайте Научной электронной библиотеки
Elibrary.ru
опубликован очередной номер Журнала аналитической химии (том 79, № 5, 2024 г.)
Содержание номера со ссылками на статьи:
Обзоры
Использование двумерной корреляционной спектроскопии в химическом анализе.
Муратова М.Е., Михеев И.В., Волков Д.С., Проскурнин М.А.
Индексы экологичности в аналитической химии.
Шишов А.Ю., Моходоева О.Б.
Оценка содержания микропластика в природных водах и донных отложениях: пробоотбор и пробоподготовка.
Ермолин М.С.
Оригинальные статьи
Новые супрамолекулярные структуры на основе наночастиц серебра и мицеллоподобных агрегатов из цетилтриметиламмония бромида.
Романовская Г.И., Королева М.В.
Определение изониазида фотометрическим методом за счет ковалентного связывания с карбоцианиновым красителем.
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Кузнецов В.В., Прокопенко Ю.Р.
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Рузметов У.У., Жумаева Э.Ш., Сманова З.А.
Выбор внутренних стандартов для определения редкоземельных элементов методом атомно-эмиссионной спектрометрии с микроволновой плазмой.
Ким П.В., Полякова Е.В., Николаев Р.Е.
Мембранная хроматографическая тест-система для определения бисфенола а в питьевой воде, основанная на использовании аптамера.
Комова Н.С., Серебренникова К.В., Берлина А.Н., Жердев А.В., Дзантиев Б.Б.
Критика и библиография
Введение в хемометрику. Интернет-издание, 2023. 372 С. С. В. Кучерявский, В. В. Панчук, Ю. Б. Монахова, Д. О. Кирсанов.
Колотов В.П.
Хроника
Юбилей Никиты Борисовича Зорова.
Юбилей Сергея Александровича Еремина.
Юбилей Ефима Соломоновича Бродского.
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118 | null | 🎯
Что такое рицин и зачем его бояться?
🔬
Рицин — это токсичный белок, который содержится в семенах клещевины. Одно семечко этого растения способно вызвать серьёзное отравление, а в больших дозах — даже смертельный исход.
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Как он работает?
Попав в организм, рицин блокирует выработку белков на клеточном уровне, буквально выключая жизненно важные процессы. А вот вам химический факт: всего 1–2 миллиграмма рицина способны убить взрослого человека, если вещество ввести инъекционно или вдохнуть.
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Где растёт клещевина?
В России её можно встретить в южных регионах, таких как Краснодарский край, Ростовская область, Крым и Кавказ. Её культивируют как декоративное растение — выглядит эффектно, а заодно добавляет адреналина садоводам!
⚠️
Серьёзная угроза:
Рицин фигурировал в ряде громких криминальных и шпионских дел. С его помощью отправляли политиков и журналистов на тот свет. Но для случайного отравления потребуется неплохая доза в виде семян, так что, если не планируете жевать клещевину, вы в безопасности.
💡
Теперь вы знаете, что за этим красивым растением скрывается опасный секрет.
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| [{"ner":"рицина способны","lemma":"рицин способный","label":"PER","start_pos":407,"end_pos":422},{"ner":"России","lemma":"россия","label":"LOC","start_pos":522,"end_pos":528},{"ner":"Краснодарский край","lemma":"краснодарский край","label":"LOC","start_pos":576,"end_pos":594},{"ner":"Ростовская область","lemma":"ростовский область","label":"LOC","start_pos":596,"end_pos":614},{"ner":"Крым","lemma":"крым","label":"LOC","start_pos":616,"end_pos":620},{"ner":"Кавказ","lemma":"кавказ","label":"LOC","start_pos":623,"end_pos":629},{"ner":"Рицин","lemma":"рицин","label":"PER","start_pos":756,"end_pos":761},{"ner":"1","lemma":"1","label":"NUM","start_pos":391,"end_pos":392},{"ner":"2","lemma":"2","label":"NUM","start_pos":393,"end_pos":394}] | NEUTRAL | rus | NOT SPAM | 162 | 0 | 3 | 1 | 0 | 0 | 22 | 23 | 7 | 2 | 43 | 11 | 35 | true |
118 | null | ГЛИКОГЕН. Печень и мышцы, есть ли разница?
Продолжая тему гликогена, давайте ответим на вопрос, есть ли разница в дальнейшей судьбе гликогена в печени и в скелетной мускулатуре?
🤔
В комментариях под предыдущим постом многие ответили совершенно верно, разница есть и она значительная!
❗️
Гликоген печени -
источник свободной глюкозы
в плазме крови!
Печень целиком и полностью накапливает гликоген, чтобы далее отдать его органам и тканям в период голода. Особенно нервной ткани!
❗️
Гликоген мышц -
источник энергии только для самих себя
. Мышцы не отдают свободную глюкозу в кровь!
Мускулатура, как ткань с высокими энергетическими потребностями, запасает гликоген только для самой себя.
Как вы считаете, обоснован ли такой механизм?
😉 | https://t.me/simplebestbiochemistry/565?embed=1&mode=tme | https://t.me/ | https://t.me/s/simplebestbiochemistry | 594 | 0 | 1,736,315,372 | 1,736,456,913 | 1,274 | 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| [{"ner":"ГЛИКОГЕН","lemma":"гликоген","label":"ORG","start_pos":0,"end_pos":8}] | NEUTRAL | rus | NOT SPAM | 110 | 0 | 2 | 1 | 0 | 0 | 11 | 13 | 5 | 0 | 41 | 6 | 22 | true |
118 | null | Какую соль выбрать?
🧂
Соль
— самая распространённая пищевая добавка, без которой не обходится ни одно блюдо в ресторане или на кухне
🥗
При этом, химический состав её предельно прост и знаком каждому.
Откуда тогда на полках в магазине берётся такое разнообразие хлорида натрия? И почему стоимость одной упаковки может быть в десять раз больше, чем другой?
Начнём с того,
как добывают пищевую соль
.
ГОСТ выделяет четыре способа производства
, которые указывают на упаковке:
Каменная соль
добывается в шахтах или карьерах из соляных залежей, не подвергаясь тепловой и водной обработке
⛏
Выварочную соль
выпаривают из соляных растворов. Бывает так, что строить целую шахту для добычи соли невыгодно. Тогда бурят небольшие скважины, заливают их водой, которая растворяет соль, затем рассол выкачивают, фильтруют и вываривают
💨
Встречаются также естественные подземные рассолы, с которыми поступают аналогичным образом.
Садочную соль
осаждают из соленой воды в специальных бассейнах. В теплый сезон в местностях с подходящим климатом вода испаряется из искусственных плоских водоёмов, оставляя следы соли
🏝
И, наконец,
самосадочная соль
— это та, которая оседает естественным образом на дне водоема. Чаще всего это озерная соль. На самом известном в России соляном озере —
Баскунчак
— получают до 80 % от общей добычи соли в стране
🗻
Согласно одному из основных законов химии —
закону постоянства состава
— определенное химически чистое соединение,
независимо от способа получения
, состоит из одних и тех же химических элементов. Вне зависимости от того,
как был получен хлорид натрия
, он будет иметь однозначную формулу NaCl и обладать одинаковыми химическими свойствами
👁
Другая сторона вопроса —
сорт соли
, который определяет внешний вид, цвет, вкус, запах и состав продукта.
ГОСТ выделяет четыре сорта
, для каждого из которых указано минимальное содержание содержание чистого хлорида натрия: экстра —
99,7%
, высший —
98,4%
, первый —
97,7%
, второй —
97%
.
Остальные проценты — это следование содержания
других минералов
, характерных для места добычи соли (кальций, магний, калий, железо и т.д.). Эти элементы необходимы для нормальной работы нашего организма, правда получаем мы их в основном из другой пищи
🍎
Как можно заметить,
соль ЭКСТРА
— это практически химически чистый реактив, подходящий для экспериментов в лаборатории
🧪
А соль
первого и второго сорта
может иметь тёмные вкрапления соединений железа и других минералов, которые никак не сказываются на её вкусовых качествах.
И другая характеристика соли — это
помол
. Занятно, что при использовании крупной соли блюдо
сложнее пересолить
, потому что в щепотке крупного помола хлорида натрия на самом деле меньше, чем в щепотке мелкого из-за наличия
пустот между кристалликами
💎
Вывод
. Как бы ни старался
современный маркетинг
, вкус дорогой морской соли ничем
не будет отличаться
от дешёвой каменной. Чем ниже сорт, тем больше содержание других
полезных элементов
, а чем крупнее помол, тем лучше соль ведёт себя
при готовке
. И не стоит
бояться
тёмных частиц — это лишь вкрапления
других минералов
.
Но обращайте внимание
на состав
😉
Иногда в соль добавляют компоненты
против слёживания и комкования
. Если вы желаете купить
натуральный продукт
, выбирайте упаковку с
наиболее кратким и лаконичным составом
👩🏻🔬 | https://t.me/ychemistry/1061?embed=1&mode=tme | https://t.me/ | https://t.me/s/ychemistry | 521 | 0 | 1,736,416,475 | 1,736,456,913 | 1,339 | 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118 | null | На видео пересыщенный раствор ацетата натрия
Добавили кристаллик ацетата натрия, чтобы спровоцировать кристаллизацию. | https://t.me/chemistrytg2021/9566?embed=1&mode=tme | https://t.me/ | https://t.me/s/chemistrytg2021 | 2,000 | 0 | 1,736,349,602 | 1,736,456,914 | 1,284 | 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| null | NEUTRAL | rus | NOT SPAM | 13 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 8 | 0 | 2 | true |
118 | null | Реакция йодида калия с серной кислотой | https://t.me/chemistrytg2021/9567?embed=1&mode=tme | https://t.me/ | https://t.me/s/chemistrytg2021 | 1,900 | 0 | 1,736,360,401 | 1,736,456,914 | 1,289 | 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| null | NEUTRAL | rus | NOT SPAM | 6 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | true |
118 | null | Жидкий метан
Это криогенная жидкость, которая легко воспламеняется, причем разница температур между пламенем и жидким метаном прямо под ним составляет более 1600C градусов! | https://t.me/chemistrytg2021/9568?embed=1&mode=tme | https://t.me/ | https://t.me/s/chemistrytg2021 | 1,700 | 0 | 1,736,403,602 | 1,736,456,914 | 1,287 | 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| [{"ner":"1600","lemma":"1600","label":"NUM","start_pos":157,"end_pos":161}] | NEUTRAL | rus | NOT SPAM | 23 | 0 | 1 | 0.962963 | 0.037037 | 0 | 3 | 2 | 3 | 1 | 7 | 3 | 3 | true |
118 | null | Подборка интересных физико-химических экспериментов, которые можно повторить в домашних условиях. | https://t.me/chemistrytg2021/9569?embed=1&mode=tme | https://t.me/ | https://t.me/s/chemistrytg2021 | 1,600 | 0 | 1,736,414,402 | 1,736,456,914 | 1,285 | 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| null | NEUTRAL | rus | NOT SPAM | 10 | 0 | 0 | 1 | 0 | 0 | 5 | 1 | 1 | 0 | 3 | 1 | 2 | true |
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118 | null | Новые мультитаргетные конъюгаты для терапии болезни Альцгеймера
Международный коллектив ученых из Института физиологически активных соединений Федерального исследовательского центра проблем химической физики и медицинской химии РАН, Института органического синтеза им. И.Я. Постовского УрО РАН, Института биохимической физики имени Н.М. Эмануэля РАН, Института Вейцмана (Израиль, Реховот), Московского государственного университета им. М.В. Ломоносова, Мичиганского университета (США, Анн-Арбор) разработал новые конъюгаты на основе ингибитора холинэстераз амиридина и салициловых производных (салициламида, салицилимина и салициламина) с алкиленовыми спейсерами различной длины. Соединения продемонстрировали высокую ингибирующую активность в отношении ацетилхолинэстеразы (АХЭ) и бутирилхолинэстеразы (БХЭ), до 3–16 раз превосходя исходный амиридин. Салициламиды со спейсерами (CH2)₆ и (CH2)₈ имели максимальные коэффициенты селективности к БХЭ. Выявлено, что конъюгаты являются обратимыми ингибиторами смешанного типа обеих холинэстераз и вытесяют пропидий из периферического анионного сайта АХЭ на уровне донепезила. Соединения проявили способность ингибировать самоагрегацию Aβ42, которая возрастала с удлинением спейсера. Полученные сведения хорошо согласуются с молекулярным докингом лигандов в АХЭ, БХЭ и Aβ42. Также было показано, что соединения демонстрируют высокую радикал-связывающую активность в ABTS-тесте (сопоставимую со стандартным антиоксидантом тролоксом) и обладают способностью связывать ионы некоторых биогенных металлов - Cu (II), Fe (II) и Zn (II). Кроме того, конъюгаты имеют благоприятную прогнозируемую кишечную абсорбцию и проницаемость гематоэнцефалического барьера.
Результаты работы опубликованы в журнале «Archiv der Pharmazie» и могут быть использованы для разработки новых многофункциональных препаратов против болезни Альцгеймера.
G.F. Makhaeva, M.V. Grishchenko, N.V. Kovaleva, N.P. Boltneva, E.V. Rudakova, T.Y. Astakhova, E.N. Timokhina, P.G. Pronkin, S.V. Lushchekina, O.G. Khudina, E.F. Zhilina, E.V. Shchegolkov, M.A. Lapshina, E.S. Dubrovskaya, E.V. Radchenko, V.A. Palyulin, Y.V. Burgart, V.I. Saloutin, V.N. Charushin, R.J. Richardson. Conjugates of amiridine and salicylic derivatives aspromising multifunctional CNS agents for potentialtreatment of Alzheimer's disease. Arch. Pharm. 2025;358: e2400819.
https://doi.org/10.1002/ardp.202400819
Источник:
ИОС УрО РАН
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118 | null | Международный научно-технический симпозиум «Повышение энергоресурсоэффективности, экологической и технологической безопасности процессов, аппаратов и производств химической и смежных отраслей промышленности», посвященный 110-летию со дня рождения Л.А. Костандова
С 26 по 27 ноября 2025 г. в Российском государственном университете им. А.Н. Косыгина пройдет Международный научно-технический симпозиум «Повышение энергоресурсоэффективности, экологической и технологической безопасности процессов, аппаратов и производств химической и смежных отраслей промышленности», посвященный 110-летию со дня рождения Л.А. Костандова, Мероприятие состоится в рамках V Международного Косыгинского форума «Современные задачи инженерных наук».
Симпозиум включает пленарные сессии, работу секций с устным и стендовым представлением докладов.
Основные направления работы симпозиума:
1) Теория и математическое моделирование, цифровые технологии в энергоресурсоэффективных процессах и технологических системах.
2) Технология и аппаратурное оформление энергоресурсоэффективных экологически и технологически безопасных процессов, аппаратов и производств химической, нефтегазоперерабатывающей, текстильной, лёгкой, пищевой, деревообрабатывающей, микробиологической, фармацевтической, целлюлозно-бумажной и других отраслей промышленности и АПК.
3) Процессы и системы защиты техносферы (производственная, экологическая и технологическая безопасность, управление рисками).
4) Современные экологически чистые инновационные технологии получения новых функциональных полимерных волокнистых и наноматериалов.
Ключевые даты:
15.03.2025 - последний срок регистрации и подачи материалов;
до 01.06.2025 – извещение о результатах рассмотрения материалов.
Рабочие языки Симпозиума – английский и русский.
К началу Симпозиума будут изданы индексируемые в РИНЦ научные труды со статьями на языке оригинала. Каждой из статей сборника научных трудов будет присвоен идентификатор DOI. Отобранные по результатам Симпозиума статьи будут опубликованы в специальных выпусках журналов, входящих в перечень ВАК (Химические волокна, Промышленные процессы и технологии и др.).
Во время Симпозиума будет организован Международный конкурс научных работ молодых участников (до 36 лет) «Цифровые решения в инженерных задачах». Конкурс нацелен на мотивацию студентов к профессиональному развитию и освоению современных цифровых технологий проектирования на базе отечественного программного обеспечения, а также формирования навыков необходимых для повышения конкурентоспособности предприятий химической и смежных отраслей промышленности.
Подробная информация о мероприятии опубликована на
сайте Симпозиума
#конференция | https://t.me/chemrussia/5202?embed=1&mode=tme | https://t.me/ | https://t.me/s/chemrussia | 1,600 | 0 | 1,736,402,623 | 1,736,456,914 | 1,272 | 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118 | null | ГЛИКОГЕН. Запас на голодные времена
Итак, продолжаем разговор про углеводы! Наш организм чрезвычайно умная биохимическая машина. Прекрасно понимая, что часть нашей жизни мы проводим в поисках пищи и состоянии голода, эволюционно организм научился накапливать запас энергии. Как я люблю говорить, «на голодные времена, когда прийдется охотиться на очередного мамонта»
🦣
.
Существуют разные биохимические механизмы депонирования энергии, но первый из них - это запас энергии в виде
гликогена
.
❗️
Гликоген - это длинная углеводная молекула, гомополисахарид, состоящая из большого числа молекул глюкозы, соединенных между собой. Выполняет функцию депонирования глюкозы.
Мы выделяем два органа накапливающие гликоген в наибольшем количестве:
1️⃣
Печень (в цитоплазме гепатоцитов);
2️⃣
Скелетная мускулатура;
Накапливается гликоген после приема пищи (адсорбтивный период), особенно высокоуглеводистой, под действием гормона инсулина.
А вот распадается гликоген обратно до чистой глюкозы в период голода (постадсорбтивный период) под действием гормона глюкагона и адреналина.
На фото
⤴️
приведена структура молекулы гликогена. В центре белок - «гликогенин» на который накручиваются сами гликогеновые нити, состоящие из тысяч остатков глюкозы, соединенных между собой.
❓
А теперь важный вопрос, есть ли разница в судьбе гликогена в печени и скелетной мускулатуре? Оба ли они пойдут в кровь в виде чистой глюкозы или есть какие-то различия?
Жду ваши варианты в комментариях
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| [{"ner":"ГЛИКОГЕН","lemma":"гликоген","label":"ORG","start_pos":0,"end_pos":8},{"ner":"1","lemma":"1","label":"NUM","start_pos":738,"end_pos":739},{"ner":"2","lemma":"2","label":"NUM","start_pos":777,"end_pos":778}] | NEUTRAL | rus | NOT SPAM | 201 | 0 | 4 | 1 | 0 | 0 | 24 | 25 | 9 | 2 | 78 | 7 | 44 | true |
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