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---
dataset_info:
features:
- name: A
dtype: string
- name: B
dtype: string
- name: SeqA
dtype: string
- name: SeqB
dtype: string
splits:
- name: combined
num_bytes: 4506410
num_examples: 6254
- name: combined_stringent
num_bytes: 4131280
num_examples: 5858
- name: manual
num_bytes: 2411342
num_examples: 2150
- name: manual_stringent
num_bytes: 2197429
num_examples: 1970
- name: pdb
num_bytes: 2116596
num_examples: 4140
- name: pdb_stringent
num_bytes: 1943225
num_examples: 3904
download_size: 8538939
dataset_size: 17306282
configs:
- config_name: default
data_files:
- split: combined
path: data/combined-*
- split: combined_stringent
path: data/combined_stringent-*
- split: manual
path: data/manual-*
- split: manual_stringent
path: data/manual_stringent-*
- split: pdb
path: data/pdb-*
- split: pdb_stringent
path: data/pdb_stringent-*
---
# Non-interacting protein pairs from NEGATOME2.0
[Website](https://mips.helmholtz-muenchen.de/proj/ppi/negatome/)
[Paper](https://pmc.ncbi.nlm.nih.gov/articles/PMC3965096/)
We map Uniprot ids with the [ID mapping tool](https://www.uniprot.org/id-mapping) and record entires in which both sequences are found. PFAM entires are ommitted.
Each split corresponds to a section of the dataset, labeled the same as the image below:

Please cite their paper if you use this dataset in your work
```
@article{Blohm2013,
title = {Negatome 2.0: a database of non-interacting proteins derived by literature mining, manual annotation and protein structure analysis},
volume = {42},
ISSN = {1362-4962},
url = {http://dx.doi.org/10.1093/nar/gkt1079},
DOI = {10.1093/nar/gkt1079},
number = {D1},
journal = {Nucleic Acids Research},
publisher = {Oxford University Press (OUP)},
author = {Blohm, Philipp and Frishman, Goar and Smialowski, Pawel and Goebels, Florian and Wachinger, Benedikt and Ruepp, Andreas and Frishman, Dmitrij},
year = {2013},
month = nov,
pages = {D396–D400}
}
```
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