passages.id: 7667
passages.type: title
passages.text: Fatal myeloencephalopathy due to intrathecal vincristine administration.
passages.id: 7668
passages.type: abstract
passages.text: Vincristine was accidentally given intrathecally to a child with leukaemia, producing sensory and motor dysfunction followed by encephalopathy and death. Separate times for administering vincristine and intrathecal therapy is recommended.