passages.id: 15008
passages.type: title
passages.text: Late, late doxorubicin cardiotoxicity.
passages.id: 15009
passages.type: abstract
passages.text: Cardiac toxicity is a major complication which limits the use of adriamycin as a chemotherapeutic agent. Cardiomyopathy is frequent when the total dose exceeds 600 mg/m2 and occurs within one to six months after cessation of therapy. A patient is reported who developed progressive cardiomyopathy two and one-half years after receiving 580 mg/m2 which apparently represents late, late cardiotoxicity.