passages.id: 1983
passages.type: title
passages.text: Increase of Parkinson disability after fluoxetine medication.
passages.id: 1984
passages.type: abstract
passages.text: Depression is a major clinical feature of Parkinson's disease. We report the increased amount of motor disability in four patients with idiopathic Parkinson's disease after exposure to the antidepressant fluoxetine. The possibility of a clinically relevant dopamine-antagonistic capacity of fluoxetine in Parkinson's disease patients must be considered.