passages.id: 14780
passages.type: title
passages.text: Reversibility of captopril-induced renal insufficiency after prolonged use in an unusual case of renovascular hypertension.
passages.id: 14781
passages.type: abstract
passages.text: We report a case of severe hypertension with an occluded renal artery to a solitary kidney, who developed sudden deterioration of renal function following treatment with captopril. His renal function remained impaired but stable during 2 years' treatment with captopril but returned to pre-treatment levels soon after cessation of the drug. This indicates reversibility in captopril-induced renal failure even after its prolonged use and suggests that no organic damage occurs to glomerular arterioles following chronic ACE inhibition.