ENTITY
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DEFINITION
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ALIASES
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C0002073
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
Alkylators|Product containing alkylating agent (product)|Alkylator|alkylating drugs|Agents, Alkylating|Alkylating agent, NOS|Alkylating agent|Alkylating Agent|Alkylating agent-containing product|alkylating agent|Alkylating agent (substance)|Alkylating Agents|agents alkylating|ALKYLATING AGENTS|alkylating agents|alkylating drug|Alkylating agents
Alkylating Agents
C0006480
Derivatives of butanone, also known as methyl ethyl ketone (with structural formula CH3COC2H5).
null
Butanones
C0216823
null
NNKOAc
4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone
C1017361
null
Hyphomicrobium denitrificans|Hyphomicrobium denitrificans (organism)
Hyphomicrobium denitrificans
C0074529
The styles (the filamentous structure of a flower that supports the pollen-containing anthers) on an ear of corn.
SILK|silk|Silk|Silk (substance)|Stylus Sericeus
Silk
C0252334
null
spider silk protein 1|dragline silk fibroin 1
spidroin 1
C1260603
null
Vegetable fiber|Fibre|fiber vegetable|Plant fibre|Plant fiber, NOS|Plant fiber|Vegetable fibre|fiber vegetables|fiber|fibres|Plant fiber (substance)|vegetable fiber|fibre|fibered|Fiber|fibre vegetables|Vegetable fiber, NOS
Plant fiber
C0887946
Any of the codons of an organism's GENETIC CODE that specify an amino acid.
Codon, Sense|Sense Codons|Codons, Sense
Sense Codon
C0024706
A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Manganese-containing product|manganese|Mn - Manganese|Manganese (substance)|Manganese|Mn|Manganese, NOS|Mn element|MANGANESE|Product containing manganese (medicinal product)
manganese
C0006632
An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
Cadmium, NOS|Cd|Cadmium (substance)|Cadmium Metal|cadmium|Cadmium|CADMIUM|cadmium (Cd)|Cd element|Cd - Cadmium
cadmium
C0006779
The measurement of the quantity of heat involved in various processes, such as chemical reactions, changes of state, and formations of solutions, or in the determination of the heat capacities of substances. The fundamental unit of measurement is the joule or the calorie (4.184 joules). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
calorimetry|Calorimetry|Calorimetry (procedure)
Calorimetry
C0011486
An enzyme that catalyzes reversibly the phosphorylation of deoxycytidine with the formation of a nucleoside diphosphate and deoxycytidine monophosphate. Cytosine arabinoside can also act as an acceptor. All natural nucleoside triphosphates, except deoxycytidine triphosphate, can act as donors. The enzyme is induced by some viruses, particularly the herpes simplex virus (HERPESVIRUS HOMINIS). EC 2.7.1.74.
DCK|NTP:deoxycytidine 5'-phosphotransferase|Deoxycytidine Kinase|ARA-C Kinase|Deoxycytidine kinase|EC 2.7.1.74|2'-Deoxycytidine Kinase|dCK|Deoxycytidine kinase (substance)|Kinase, Deoxycytidine
Deoxycytidine Kinase
C0065573
null
maleimide
Maleimide
C0011486
An enzyme that catalyzes reversibly the phosphorylation of deoxycytidine with the formation of a nucleoside diphosphate and deoxycytidine monophosphate. Cytosine arabinoside can also act as an acceptor. All natural nucleoside triphosphates, except deoxycytidine triphosphate, can act as donors. The enzyme is induced by some viruses, particularly the herpes simplex virus (HERPESVIRUS HOMINIS). EC 2.7.1.74.
DCK|NTP:deoxycytidine 5'-phosphotransferase|Deoxycytidine Kinase|ARA-C Kinase|Deoxycytidine kinase|EC 2.7.1.74|2'-Deoxycytidine Kinase|dCK|Deoxycytidine kinase (substance)|Kinase, Deoxycytidine
Deoxycytidine Kinase
C0729920
null
Multisystem disorder E-F (navigational concept)
Multisystem disorder E-F
C0023837
An enzyme of the oxidoreductase class primarily found in PLANTS. It catalyzes reactions between linoleate and other fatty acids and oxygen to form hydroperoxy-fatty acid derivatives.
carotene oxidase|Oxidoreductase, Linoleate-Oxygen|Carotene oxidase|Lipoxidase|Linoleate Oxygen Oxidoreductase|Linoleate-Oxygen Oxidoreductase|lipoxygenase|Lipoxygenase (substance)|Linoleate:oxygen 13-oxidoreductase|Lipoxygenase|lipoxidase
Lipoxygenase
C1259205
null
null
12-15-lipoxygenase
C1259205
null
null
12-15-lipoxygenase
C0015857
An enzyme that catalyzes the oxidation and reduction of FERREDOXIN or ADRENODOXIN in the presence of NADP. EC 1.18.1.2 was formerly listed as EC 1.6.7.1 and EC 1.6.99.4.
Reductase, Ferredoxin-NADP|Reductase, Iron-Sulfur Protein|Ferredoxin-NADP^+^ reductase|Ferredoxin-NADP reductase|Reductase, Adrenodoxin|Ferredoxin-NADP<sup>+</sup> reductase|Ferredoxin:NADP+ oxidoreductase|Iron Sulfur Protein Reductase|Ferredoxin-nicotinamide adenine dinucleotide phosphate + reductase (substance)|NADPH-Ferredoxin Reductase|Ferredoxin-nicotinamide adenine dinucleotide phosphate ^+^ reductase|Adrenodoxin Reductase|Ferredoxin-NADP+ reductase|Iron-Sulfur Protein Reductase|Ferredoxin-nicotinamide adenine dinucleotide phosphate + reductase|Reductase, NADPH-Ferredoxin|Ferredoxin-nicotinamide adenine dinucleotide phosphate <sup>+</sup> reductase|Ferredoxin NADP Reductase|Protein Reductase, Iron-Sulfur|NADPH Ferredoxin Reductase|Ferredoxin-NADP Reductase|Adrenodoxin reductase|Ferredoxin-nicotinamide adenine dinucleotide phosphate ^+^ reductase (substance)|Ferredoxin-nicotinamide adenine dinucleotide phosphate <sup>+</sup> reductase (substance)
Ferredoxin-NADP Reductase
C0597305
A taxonomic kingdom that includes algae, protozoa, slime molds, and water molds. Members of kingdom protista are aerobic and may be unicellular, multicellular, or colony forming. Additionally, protista require a water-based environment to survive. All protista are true eukaryotes with a nuclear membrane and mitochondria. Some protista also contain chloroplasts and can perform photosynthesis. Protists reproduce by mitosis or meiosis.
protist|protista|Protista|protists|Protist
Protista
C0120447
The hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity. Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptors. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes. (NCI05)
Guanidinium Chloride|Guanidine hydrochloride|Chloride, Guanidinium|Guanidium Chloride|Chloride, Guanidium|Guanidine Hydrochloride|GUANIDINE HYDROCHLORIDE|Guanidine Monohydrochloride|Monohydrochloride, Guanidine|Guanidine hydrochloride (substance)|Hydrochloride, Guanidine|Aminoformamidine Hydrochloride
guanidine hydrochloride
C1522172
null
Onconase
Onconase
C0162621
<p>Titration</p>
titration|Titration method|Titration method (procedure)|titrations|Titration
Titration Method
C0035899
Genes, found in both prokaryotes and eukaryotes, which are transcribed to produce the RNA which is incorporated into RIBOSOMES. Prokaryotic rRNA genes are usually found in OPERONS dispersed throughout the GENOME, whereas eukaryotic rRNA genes are clustered, multicistronic transcriptional units.
Ribosomal RNA Gene|Gene, Ribosomal RNA|Gene, rRNA|rRNA Gene|Genes, Ribosomal RNA|Ribosomal RNA Genes|Ribosomal DNA|rDNA|rRNA Genes|RNA Gene, Ribosomal|Genes, rRNA|RNA Genes, Ribosomal
Ribosomal RNA Genes
C0007343
Oil obtained from seeds of Ricinus communis that is used as a cathartic and as a plasticizer.
Ricinus persicus oil|Ricinus speciosus oil|castor|Ricinus communis oil|Ricinus metallicus oil|Ricinus gibsonii oil|ricini oleum|Ricinus viridis oil|Oleum ricini|Ricinus communis seed oil|Ricinus zanzibarinus|Toto ni vavalagi oil|Castor oil (substance)|Oil, Castor|Ricinus undulatus oil|Ricinus obermannii oil|castor oil|Croton spinosus oil|Cataputia minor oil|Ricinus armatus oil|Agaliya oil|Ricinus inermis oil|Ricinus peltatus oil|Product containing castor oil (medicinal product)|Ricinus europaeus oil|Ricinus laevis oil|Ricinus zanzibarensis oil|Ricinus badius oil|Ricinus rutilans oil|Ricinus medicus oil|Ricinus tunisensis oil|Ricinus compactus oil|Bimayou|castor eyes oil|Ricinus spectabilis oil|Ricinus lividus oil|Ricinus digitatus oil|Ricinus nanus oil|Ricinus communis castor seed oil|Ricinus japonicus oil|Maskerekur oil|oleum ricini|Ricinus scaber oil|castor oil laxative|Cataputia major oil|Ricinus africanus oil|Ricinus macrophyllus oil|Ricinus rugosus oil|Ricinus communis (castor) seed oil|Ricinus atropurpureus oil|Ricinus cambodgensis oil|Ricinus communis fibre oil|Ricinus ruber oil|Ricinus macrocarpus oil|Ricinus oil|Castor oil-containing product|Ricinus glaucus oil|Uluchula skoki oil|Ricinus messeniacus oil|Ricinus microcarpus oil|Ricinus krappa oil|Castor Oil|Ricinus hybridus oil|Castor oil|Ricinus minor oil|Ricinus vulgaris oil|Lama palagi oil|Ricinus sanguineus oil|Castorbean oil|CASTOR OIL|Ricinus borboniensis oil|Ricinus perennis oil|Ricinus medius oil|Ricinus purpurascens oil|Ricinus angulatus oil|Ricinus urens oil|Ricinus giganteus oil
castor oil
C0024553
A country in southern Asia, occupying a group of atolls in the Indian Ocean, south-southwest of India and north of the British Indian Ocean Territory.
MV|Maldives|MALDIVES|MDV|Maldives (geographic location)
Maldives
C0024553
A country in southern Asia, occupying a group of atolls in the Indian Ocean, south-southwest of India and north of the British Indian Ocean Territory.
MV|Maldives|MALDIVES|MDV|Maldives (geographic location)
Maldives
C0014553
A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
EPILEPSY IDIOPATHIC PETIT MAL|EPILEPSY, PETIT MAL|PETIT MAL EPILEPSY|PRIMARY GENERALIZED EPILEPSY, MINOR|Simple absence|Absence Epilepsy|Petit-mal seizure|mals petit|seizures absence|Absences, typical|Absence, typical|Typical absence seizure|Epilepsy, Absence|petit mal epilepsy|PETIT MAL CONVULSION|absence epilepsy|Minor epilepsy|Petit mal epilepsy|Petit mal, typical|Typical absence seizures|absences epilepsy|absence seizures|Absence seizure|childhood absence epilepsy|EPILEPSY PETIT MAL|mal petit|Absence seizures|absence seizure|Typical absence seizure (disorder)|typical absence|mal petit seizure|Absence seizure (disorder)|petit mal seizure|EPILEPSY, MINOR|petit mal seizures|epilepsy absence|seizure petit mal|Petit Mal Epilepsy|Epilepsy, Petit Mal|absence seizure disorder|ABSENCE EPILEPSY|ABSENCE SEIZURE|CONVULSION PETIT MAL|petit mal|minor epilepsy|mal petit seizures|PETIT MAL|Petit mal
Absence Epilepsy
C0014553
A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
EPILEPSY IDIOPATHIC PETIT MAL|EPILEPSY, PETIT MAL|PETIT MAL EPILEPSY|PRIMARY GENERALIZED EPILEPSY, MINOR|Simple absence|Absence Epilepsy|Petit-mal seizure|mals petit|seizures absence|Absences, typical|Absence, typical|Typical absence seizure|Epilepsy, Absence|petit mal epilepsy|PETIT MAL CONVULSION|absence epilepsy|Minor epilepsy|Petit mal epilepsy|Petit mal, typical|Typical absence seizures|absences epilepsy|absence seizures|Absence seizure|childhood absence epilepsy|EPILEPSY PETIT MAL|mal petit|Absence seizures|absence seizure|Typical absence seizure (disorder)|typical absence|mal petit seizure|Absence seizure (disorder)|petit mal seizure|EPILEPSY, MINOR|petit mal seizures|epilepsy absence|seizure petit mal|Petit Mal Epilepsy|Epilepsy, Petit Mal|absence seizure disorder|ABSENCE EPILEPSY|ABSENCE SEIZURE|CONVULSION PETIT MAL|petit mal|minor epilepsy|mal petit seizures|PETIT MAL|Petit mal
Absence Epilepsy
C0041044
A drug combination with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.
trimethoprim-sulfamethoxazole|sulfamethoxazole-trimethoprim|smz-tmp|centrin|Bactrimel|Sulfamethoxazole / Trimethoprim|trimethoprim-sulphamethoxazole|Sulfamethoxazole/ Trimethoprim|co-trimazole|co trimoxazole|Trimethoprim-Sulfamethoxazole Combination|Trimethoprim, Sulfamethoxazole Drug Combination|Co Trimoxazole|Trimethoprim-Sulfamethoxazole|Trimethoprim-sulfamethoxazole|Co-trimoxazole|Co-trimazole|tmp smx|Sulfamethoxazole and trimethoprim|smx tmp|Trimedin|trimezole|Sulfamethoxazole-trimethoprim|Centran|trimedin|insozalin|co-trimoxazole|sulfamethoxazole trimethoprim|SMZ-TMP|Trimethoprim Sulfamethoxazole|SMX-TMP|Sulfamethoxazole-Trimethoprim Combination|tmp-smx|Sulfamethoxazole and trimethoprim (substance)|TMP-SMX|Product containing sulfamethoxazole and trimethoprim (medicinal product)|smx-tmp|trimethoprim sulfamethoxazole|SULFAMETHOXAZOLE/TRIMETHOPRIM|Insozalin|Sulfamethoxazole- and trimethoprim-containing product|Trimethoprim Sulfamethoxazole Combination|Cotrimoxazole|cotrimoxazole|TMP SMX|Eslectin|smz tmp|Centrin|sulfamethoxazole and trimethoprim|Trimezole|Sulfamethoxazole Trimethoprim Combination|Benzenesulfonamide, 4-a)mino-N-(5-methyl-3-isoxazolyl)-, mixt. with 5-((3,4,5-trimethoxyphenyl)methyl-2,4-pyrimidinediamine|Co-Trimoxazole
Trimethoprim-Sulfamethoxazole Combination
C0872241
null
null
PDZ protein
C0679729
null
cooperative|cooperatives
cooperative
C0872367
null
null
single molecule
C0077194
null
TMAO|trimethylamine oxide|N,N-dimethylmethanamine N-oxide|trimethylamine N-oxide|trimethylammonium oxide
trimethyloxamine
C0077194
null
TMAO|trimethylamine oxide|N,N-dimethylmethanamine N-oxide|trimethylamine N-oxide|trimethylammonium oxide
trimethyloxamine
C0004627
Proteins found in any species of bacterium.
bacterial protein|Protein, Bacterial|Gene Product, Bacterial|Gene Products, Bacterial|Bacterial Gene Protein|Bacterial proteins|Bacterial Gene Product|Bacterial Protein|Bacterial protein|Proteins, Bacterial|Bacterial Gene Products|Gene Protein, Bacterial|Gene Proteins, Bacterial|bacterial proteins|Bacterial protein (substance)|Bacterial Gene Proteins
Bacterial Proteins
C0035553
Multicomponent ribonucleoprotein structures found in the CYTOPLASM of all cells, and in MITOCHONDRIA, and PLASTIDS. They function in PROTEIN BIOSYNTHESIS via GENETIC TRANSLATION.
Ribosoma|Ribosomes|Ribosome (cell structure)|Ribosome|ribosome|Ribosomal|Ribosome, NOS|ribosomes
Ribosomes
C0046319
A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS.
2 Methoxyestradiol|2-Hydroxyestradol 2-methyl ether|2-methoxy-17β-estradiol|2-METHOXYESTRADIOL|2-ME2|2-Methoxyestradiol-17beta|2-Methoxyoestradiol|2 methoxyestradiol|2-ME|Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-|2 Methoxyoestradiol|2-Hydroxyestradiol 2-methyl ether|2-Methoxyestradiol|2-methoxyestradiol|2-MeE2|2-MeOE2|(17 beta)-2-methoxyestra-1,3,5(10)-triene-3,17-diol|(17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol|2-Methoxy Estradiol|2ME2
2-methoxyestradiol
C1335424
null
Plantar Verrucous Carcinoma of Skin|Plantar Verrucous Carcinoma of the Skin
Plantar Verrucous Skin Carcinoma
C1335424
null
Plantar Verrucous Carcinoma of Skin|Plantar Verrucous Carcinoma of the Skin
Plantar Verrucous Skin Carcinoma
C1335424
null
Plantar Verrucous Carcinoma of Skin|Plantar Verrucous Carcinoma of the Skin
Plantar Verrucous Skin Carcinoma
C0243725
null
Cycloartenol synthase|2,3-epoxysqualene cycloartenol-cyclase|Cycloartenol synthase (substance)|2,3-Epoxysqualene cycloartenol-cyclase|2,3-epoxysqualene cycloartenol synthase|2,3-oxidosqualene cycloartenol cyclase|2,3-oxidosqualene cycloartenol-cyclase|cycloartenol synthase
Cycloartenol synthase
C0243725
null
Cycloartenol synthase|2,3-epoxysqualene cycloartenol-cyclase|Cycloartenol synthase (substance)|2,3-Epoxysqualene cycloartenol-cyclase|2,3-epoxysqualene cycloartenol synthase|2,3-oxidosqualene cycloartenol cyclase|2,3-oxidosqualene cycloartenol-cyclase|cycloartenol synthase
Cycloartenol synthase
C0007465
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
causes of death|death causes|death diagnosis|Cause of Death|Cause of death (observable entity)|major cause of death|Death diagnosis (contextual qualifier) (qualifier value)|Death Causes|Death diagnosis (contextual qualifier)|COD|Causes of Death|Major cause of death|Condition fatal-cause of death|Death Diagnosis|Cause of death|DEATHD|Death diagnosis|Death Cause|Death--Causes|DD|death cause|cause of death
Cause of Death
C0752284
null
mu Conotoxins|mu Conotoxin|mu-Conotoxin
mu-Conotoxins
C0025914
The common mouse species, Mus musculus.
Mice|House Mice|House Mouse|mice|House mouse|mus musculus|mouse, mice|Mus musculus|Common house mouse|Mouse, House|Mouse (organism)|Mus musculus (organism)|house mouse|Mice, House|Mouse|house mice|Old World mouse|mouse|Mouse, NOS|mouse <Mus musculus>|MUS MUSCULUS|Old World mouse (organism)
House mice
C0009498
The complement system is a complex system of serum proteins that interact in a cascade. Many of the early components are serine proteases that activate each other sequentially. This complement system consists of three separate activation triggers: (1) Ab binding to a cell surface, (2) formation of immune complexes, and (3) a carbohydrate component of a microbe's cell membrane. Along with this triggers, there are also two sets of mechanisms. Both of these mechanisms, classical pathway and alternative or properdin pathway, make MAC (Membrane Attack Complex), which can lyse and destroy the cell.
Complement Proteins|complements|Proteins, Complement|Proteins, Complement System|Protein, Complement|complement (serum protein)|Complement, thermolabile serum protein complex with cytotoxic effect (substance)|complement|Complement, thermolabile serum protein complex with cytotoxic effect|complement proteins|Complement|complement protein|Complement System Proteins|Complement, NOS|Complement Component Protein|Complement Protein
Complement System Proteins
C0012888
A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair. EC 2.7.7.7.
Polymerase I, DNA|Alpha DNA polymerase|Polymerase alpha, DNA|DNA Pol I|DNA-Dependent DNA Polymerase I|DNA Polymerase Alpha|DNA Dependent DNA Polymerase I|DNA Polymerase alpha|DNA Polymerase I|Klenow Fragment
DNA Polymerase I
C1148824
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. [GOC:mah, ISBN:0198547684]
exonuclease activity
exonuclease activity
C0001407
A purine base and a fundamental unit of ADENINE NUCLEOTIDES.
6-Aminopurine|4, Vitamin B|Adenine|Vitamin B>4<|Adenin|B 4, Vitamin|Vitamin B 4|adenine|Vitamin B4|1H-Purin-6-amine|Adenine (substance)|vitamin b4|ADENINE|Vitamin B<sub>4</sub>|6-aminopurine
adenine
C0018321
A chemical compound that is used to make one of the building blocks of DNA and RNA. It is a type of purine.
guanine|2-Amino-1,7-dihydro-6H-purin-6-one|2-Amino-6-Hydroxypurine|Guanine|GUANINE|6H-Purin-6-one, 2-amino-1,7-dihydro-|Guanine (substance)
guanine
C0081342
null
4H-pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-1,7-dihydro-|N7-deazaguanine
7-deazaguanine
C0054362
null
C1027 chromoprotein|C-1027|C1027 chromophore
C 1027
C0025255
Thin layers of tissue which cover parts of the body, separate adjacent cavities, or connect adjacent structures.
membrane|Membranous|Membrane Tissue|Tissues, Membrane|Membranes|Tissue, Membrane|membranes|Membrane|Membrane Tissues
Tissue membrane
C0376436
A collection of cloned peptides, or chemically synthesized peptides, frequently consisting of all possible combinations of amino acids making up an n-amino acid peptide.
Peptide Libraries|Libraries, Peptide|peptide library|Library, Peptide
Peptide Library
C0005446
1,3,6,7-Tetramethyl-4,5-dicarboxyethyl-2,8-divinylbilenone. Biosynthesized from hemoglobin as a precursor of bilirubin. Occurs in the bile of AMPHIBIANS and of birds, but not in normal human bile or serum.
biliverdin|Biliverdin|Dehydrobilirubin|Ooecyan|Biliverdin (substance)|Uteroverdine|21H-Biline-8,12-dipropanoic acid, 3,18-diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-
Biliverdine
C0005433
null
Bilin
Bilin
C0070982
null
biline-8,12-dipropionic acid, 18-ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-|21H-biline-8,12-dipropanoic acid, 18-ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-, (2R,3E)-|3(E)-phycocyanobilin
phycocyanobilin
C0040048
Constituent composed of protein and phospholipid that is widely distributed in many tissues. It serves as a cofactor with factor VIIa to activate factor X in the extrinsic pathway of blood coagulation.
thromboplastin|Tissue factor|Thromboplastin (substance)|Tissue Factor|Factor III, Coagulation|Thromboplastin preparation|Procoagulant Activity, Glomerular|Urothromboplastin|Prothrombinase|Antigens, CD142|tissue thromboplastin|Thromboplastin|Procoagulant, Tissue Factor|Tissue Factor Procoagulant|coagulation factor III|Coagulation factor III|Blood-coagulation factor III|factors tissue|Thromboplastin, NOS|Blood Coagulation Factor III|Factor III|prothrombinase|factor iii|Tissue thromboplastin|tissue factor|Glomerular Procoagulant Activity|CD142 Antigens|Activity, Glomerular Procoagulant|Coagulation Factor III|Coagulin|Tissue Thromboplastin|Thromboplastin, Tissue
Thromboplastin
C0015505
Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagulation.
Factor VII, Activated|Coagulation Factor VIIa|Coagulation factor VIIa|factor viia|Factor 7A|Factor VIIa|Blood Coagulation Factor VII, Activated|Activated Factor VII|Product containing coagulation factor VIIa (medicinal product)|Coagulation factor VIIa (substance)|Activated factor VII|Coagulation factor VIIa-containing product|coagulation factor viia|Factor Seven A|Factor VIIa, Coagulation
factor VIIa
C0404325
null
Labor operations|Labour operations|Labor procedure|Labour procedure|Induction and delivery procedures (procedure)
Induction and delivery procedures
C0949660
Myosin type II isoforms found in skeletal muscle.
Myosins, Skeletal Muscle
Skeletal Muscle Myosins
C0525082
null
3-Morpholinosydnoneimine|N-morpholino sydnonimine|LINSIDOMINE|3-morpholinosydonimine|SIN-1 morpholine|3-morpholino-sydnonimine|linsidomine|Linsidomine
linsidomine
C0525082
null
3-Morpholinosydnoneimine|N-morpholino sydnonimine|LINSIDOMINE|3-morpholinosydonimine|SIN-1 morpholine|3-morpholino-sydnonimine|linsidomine|Linsidomine
linsidomine
C0053646
null
biotin synthetase|Biotin synthetase|biotin synthase|Biotin synthase|Biotin synthase (substance)
biotin synthase
C0053646
null
biotin synthetase|Biotin synthetase|biotin synthase|Biotin synthase|Biotin synthase (substance)
biotin synthase
C0871215
null
reading disabilities|Reading disability|disabilities reading|disability reading
Reading Disabilities
C0234725
null
hearing normal|Hearing normal (finding)|normal hearing|Normal hearing, NOS|Normal hearing
Hearing normal
C0026192
A subgroup having special characteristics within a larger group, often bound together by special ties which distinguish it from the larger group.
Minorities|Minority Group|Minority|Ethnic and Racial Minorities|minority|minorities|Group, Minority|Groups, Minority|minority group|minority groups
Minority Groups
C0599894
The process of directing an agent to a specific anatomic location.
Targeted|targeting|Targeting
cellular targeting
C0004340
The smallest continent and an independent country, comprising six states and two territories. Its capital is Canberra.
AU|Australia (geographic location)|AUS|Australia|AUSTRALIA
Australia
C0016674
A country in western Europe bordered by the Atlantic Ocean, the English Channel, the Mediterranean Sea, and the countries of Belgium, Germany, Italy, Spain, Switzerland, the principalities of Andorra and Monaco, and by the duchy of Luxembourg. Its capital is Paris.
FR|FRA|FRANCE|France|france|France (geographic location)
France
C0041700
Country in northwestern Europe including Great Britain and the northern one-sixth of the island of Ireland, located between the North Sea and north Atlantic Ocean. The capital is London.
UNITED KINGDOM|United Kingdom of Great Britain and Northern Ireland (geographic location)|United Kingdom of Great Britain and Northern Ireland|kingdom united|GBR|united kingdom|United Kingdom|UK - United Kingdom of Great Britain and Northern Ireland|GB
United Kingdom
C0018735
Decisions, usually developed by government policymakers, for determining present and future objectives pertaining to the health care system.
health care policy|health policies|health policy|Health Policies|Health Policy|Policy, Health|Policies, Health
Health Policy
C0038435
The response of the body to physical, mental, or emotional pressure. This may make a person feel frustrated, angry, or anxious, and may cause unhealthy chemical changes in the body. Untreated, long-term stress may lead to many types of mental and physical health problems.
Stress (qualifier value)|Stress (finding)|State of stress|Stress, NOS|stressed|Stress - value|Stress|stress
Stress
C0681592
null
driving performance
driver performance
C0042693
Individual or group aggressive behavior which is socially non-acceptable, turbulent, and often destructive. It is precipitated by frustrations, hostility, prejudices, etc.
violence|Violence
Violence
C0025071
Federal program, created by Public Law 89-97, Title XIX, a 1965 amendment to the Social Security Act, administered by the states, that provides health care benefits to indigent and medically indigent persons.
Medicaid Program|Medicaid coverage|MEDICAID|Medicaid coverage (finding)|Medicaid|medicaid
Medicaid
C0725066
null
Advance|Advance [medical device]
Advance -- medical device
C0009586
Providing for the full range of personal health services for diagnosis, treatment, follow-up and rehabilitation of patients.
Healthcare, Comprehensive|Health Care, Comprehensive|Comprehensive Care|care comprehensive health|Comprehensive Healthcare|comprehensive care
Comprehensive Health Care
C0150134
null
anticipatory guidance|Anticipatory guidance (procedure)
Anticipatory guidance
C0004448
The act of "taking account" of an object or state of affairs. It does not imply assessment of, nor attention to the qualities or nature of the object.
Situation Awareness|Awarenesses, Situational|Situation Awarenesses|Situational Awareness|Cognitive function: awareness|Awarenesses|Awareness, Situational|Aware|Awareness, Situation|awareness|Cognitive function: awareness (observable entity)|Awarenesses, Situation|Awareness|Situational Awarenesses
Awareness
C0078569
An antidepressant drug that is being evaluated for the treatment of hot flashes in women who have breast cancer.
Venlafaxine (substance)|Venlafaxina|Venlafaxinum|1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)cyclohexanol|VNF|venlafaxine|Product containing venlafaxine (medicinal product)|VENLAFAXINE|Venlafaxine|Venlafaxine-containing product
venlafaxine
C0001675
A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.
adults|Adults|Adult (person)|21 old year|Human, Adult|21 year old|adult human (21+)|ADULT|Adult|adult|21+ years old|Adult Human (21+)
Adult
C0681797
null
paradigms|paradigm
paradigm
C0149931
A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.
HEADACHE, MIGRAINE|Migraine Disorders|MIGRAINE HEADACHE|Migraine headache|Disorders, Migraine|Migraine, NOS|migraines|migraine headache|Migraine Headaches|Migraines|Disorder, Migraine|Headaches, Migraine|headache migraines|disorder migraine|disorders migraine|Migraine (disorder)|Headache, Migraine|migraine|Migraine Headache|migraine syndromes|Migraine headaches|migraine syndrome|MIGRAINE SYNDROME|migraine nos|Migraine|MIGRAINE|MIGRAINES|Migraine, unspecified|migraine headaches|Migraine Disorder
Migraine Disorders
C0262405
null
dysfunction brain|CEREBRAL DYSFUNCTION|Cerebral dysfunction syndrome|brain dysfunctions|cerebral dysfunction|Diminished intellectual function syndrome|brain dysfunction
Cerebral dysfunction
C0006055
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
Toxin, Botulinum|Botulism toxin|Toxins, Botulinum|botulinum toxin|Botulinum Toxins|Toxin, botulinum|Clostridium botulinum toxin|botulinum toxins|Clostridium botulinum toxin (substance)|Botulinum Toxin|botulin|Clostridium botulinum Toxins|clostridium botulinum toxin|Botulin toxin|Product containing Clostridium botulinum toxin (medicinal product)|Botulinum toxin|Clostridium botulinum toxin-containing product|botulinum toxin (BTX)|Toxins, Clostridium botulinum|Botulin
Botulinum Toxins
C0393738
null
Chronic tension type headache|Chronic tension-type headache (disorder)
Chronic tension-type headache
C0151293
null
chronic headache|Headaches, Chronic|Chronic Headaches|chronic headaches|Headache, Chronic|Headache, chronic|Chronic headaches|headaches chronic
Chronic Headache
C0006055
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
Toxin, Botulinum|Botulism toxin|Toxins, Botulinum|botulinum toxin|Botulinum Toxins|Toxin, botulinum|Clostridium botulinum toxin|botulinum toxins|Clostridium botulinum toxin (substance)|Botulinum Toxin|botulin|Clostridium botulinum Toxins|clostridium botulinum toxin|Botulin toxin|Product containing Clostridium botulinum toxin (medicinal product)|Botulinum toxin|Clostridium botulinum toxin-containing product|botulinum toxin (BTX)|Toxins, Clostridium botulinum|Botulin
Botulinum Toxins
C0006055
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
Toxin, Botulinum|Botulism toxin|Toxins, Botulinum|botulinum toxin|Botulinum Toxins|Toxin, botulinum|Clostridium botulinum toxin|botulinum toxins|Clostridium botulinum toxin (substance)|Botulinum Toxin|botulin|Clostridium botulinum Toxins|clostridium botulinum toxin|Botulin toxin|Product containing Clostridium botulinum toxin (medicinal product)|Botulinum toxin|Clostridium botulinum toxin-containing product|botulinum toxin (BTX)|Toxins, Clostridium botulinum|Botulin
Botulinum Toxins
C0011304
Breakdown, or abnormal development, of a nerve fiber myelin sheath.
DEMYELINATION|Demyelination|Myelinoclasis|Demyelination, NOS|demyelination|Axon demyelination|myelinolysis|Demyelination (morphologic abnormality)|Demyelinations|Neuronal demyelination|Dysmyelination|Myelinolysis
Demyelination
C0026259
An anthracenedione-derived antineoplastic agent.
DHAD|1,3-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione|1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthroquinone|1,3-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthracenedione|1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9, 10-anthroquinone|Mitoxantrone-containing product|DHAQ|Mitoxantronum|mitoXANtrone|Mitoxantrone (substance)|Dihydroxyanthracenedione|1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinone|9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-|dihydroxyanthracenedione|mitozantrone|MITOXANTRONE|Mitoxantrona|Mitozantrone|Product containing mitoxantrone (medicinal product)|Mitoxantrone|mitoxantrone
mitoxantrone
C0259961
null
Parenteral therapy
parenteral therapy
C1172734
A humanized recombinant IgG4 monoclonal antibody directed against the alpha4 subunit of the integrins alpha4beta1and alpha4beta7 with immunomodulating, anti-inflammatory, and potential antineoplastic activities. Natalizumab binds to the alpha4-subunit of alpha4beta1 and alpha4beta7 integrins expressed on the surface of all leukocytes except neutrophils, inhibiting the alpha4-mediated adhesion of leukocytes to counter-receptor(s) such as vascular cell adhesion molecule-1 (VCAM-1); natalizumab-mediated disruption of VCAM-1 binding by these integrins may prevent the transmigration of leukocytes across the endothelium into inflamed parenchymal tissue. Integrins are cellular adhesion molecules (CAMs) that are upregulated in various types of cancer and some autoimmune diseases; alpha4beta1 integrin (VLA4) has been implicated in the survival of myeloma cells, possibly by mediating their adhesion to stromal cells.
Natalizumab|Anti-VLA4|NATALIZUMAB|Product containing natalizumab (medicinal product)|Natalizumab-containing product|Anti-alpha4 integrin|natalizumab|Natalizumab (substance)
natalizumab
C0015259
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
Physical exercise, NOS|Exercises, Physical|Exercise (observable entity)|Activity, Physical|Exercises|Physical Activities|Physical Exercise|Activities, Physical|PHYSICAL EXERCISES|Exercise, Physical|Physical Exercises|exercises|exercise|Physical exercises|Physical exercise (observable entity)|Exercise|physical exercises|Physical Activity|physical exercise|Physical exercise|Physical exercises (regime/therapy)|Exercise Type|physical conditioning
Exercise
C0524851
Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
degenerative disorders neurologic|Degenerative Neurologic Disorder|neurodegenerative diseases|neurodegenerative disease|Degenerative Neurologic Disease|Degenerative Neurologic Diseases|Neurologic Degenerative Condition|Nervous System Degenerative Diseases|Neurodegenerative disease|Neurologic Disorders, Degenerative|degenerative neurologic diseases|Neurologic Degenerative Conditions|Degenerative disease or syndrome of nervous system|Neurologic Disease, Degenerative|Neurologic Degenerative Disease|Neurologic Degenerative Diseases|Neurodegenerative Diseases|Neurodegenerative diseases|Degenerative Diseases and Syndromes of Nervous System|Degenerative Diseases, Nervous System|Neurologic Disorder, Degenerative|Degenerative Conditions, Neurologic|Neurodegenerative Disorders|diseases neurodegenerative|Degenerative Neurologic Disorders|disease neurodegenerative|Degenerative Condition, Neurologic|neurodegenerative disorders|Neurologic Diseases, Degenerative|neurodegenerative disorder|Degenerative Diseases, Neurologic|Neurodegenerative Disorder|Neurodegenerative Disease|degenerative neurologic disorder
Neurodegenerative Disorders
C0220931
to form by instruction, discipline, or drill; to teach so as to make fit, qualified, proficient or prepared.
Functional training|training|Functional training (procedure)|Training
Training
C0001617
Hormones synthesized in the cortex of the adrenal gland and consist of two subclasses, glucocorticoids (carbohydrate regulation) and mineralocorticoids (electrolyte regulation).
adrenal cortical hormone|Adrenal cortex hormone-containing product|Product containing adrenal cortex hormone (product)|Corticosteroids|adrenocorticosteroids|Adrenal cortical hormone-containing product|Adrenal cortical hormone, NOS|Adrenocorticosteroids|Product containing corticosteroid and corticosteroid derivative (product)|adrenal cortex hormones|Therapeutic Corticosteroid|Corticoids|Adrenal Cortex Hormones|corticoids|Corticosteroid|corticosteroids|adrenal corticosteroid|Corticosteroid and corticosteroid derivative-containing product|corticosteroid|Corticoid preparation, NOS|corticoid|Corticoid|adrenal corticosteroids|Adrenal cortical hormone|ADRENAL CORTICOSTERIODS|Adrenal cortex hormone|adrenal cortex hormone|Adrenal cortex hormone (substance)|Hormones, Adrenal Cortex
Adrenal Cortex Hormones