ENTITY
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DEFINITION
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ALIASES
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C0085087
Cell lines whose original growing procedure consisted being transferred (T) every 3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines have been developed using several different strains of mice. Tissues are usually fibroblasts derived from mouse embryos but other types and sources have been developed as well. The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.
3T3 Cell|Cell, 3T3|3T3 cell|Cells, 3T3
3T3 Cells
C0050181
null
9-(3-hydroxy-2-phosphonomethoxypropyl)adenine|HPMPA
9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine
C0596110
agent that suppresses urine formation.
antidiuretics|antidiuretic
antidiuretic
C0208757
A subclass of cannabinoid receptor found primarily on immune cells where it may play a role modulating release of CYTOKINES.
CB2, Cannabinoid Receptor|Receptor CB2, Cannabinoid|Cannabinoid Receptor CB2|CB2 Receptor|Receptor, CB2|Receptor, Cannabinoid, CB2
Receptor, Cannabinoid, CB2
C0913252
null
DAG-lactone
(1-(hydroxymethyl)-4-(4-methyl-3-(methylethyl)pentylidene)-3-oxo-2-oxolanyl)methyl 4-methyl-3-(methylethyl)pentanoate
C0379526
null
alpha Secretase|alpha secretase
alpha-Secretase
C0209738
A reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
Lamivudine|3tc|Lamivudine (substance)|Lamivudinum|4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone|lamivudine|Product containing lamivudine (medicinal product)|2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-|3'-Thia-2',3'-dideoxycytidine|Lamivudin|(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine|LAMIVUDINE|beta-L-2',3'-Dideoxy-3'-thiacytidine|Lamivudine-containing product|lamiVUDine|Lamivudina|2'3' dideoxy 3' thiacytidine|3TC|(-)-2'-Deoxy-3'-thiacytidine|2',3' Dideoxy 3' thiacytidine|2',3'-Dideoxy-3'-thiacytidine|beta-L-3'-Thia-2',3'-dideoxycytidine|LAM
lamivudine
C0060636
null
Dioxolane (substance)|dioxolane|Dioxolane|1,3-dioxolane (substance)|1,3-dioxolane
formal glycol
C0013254
An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Diethylenetriaminepentaacetic acid|Diethylenetriamine pentaacetic acid|Pentaind|Pentetic Acid|DETAPAC|(Diethylenetriamine)pentaacetic acid|pentetic acid|DTP-A|DTPA - Diethylenetriaminepentaacetic acid|DIETHYLENETRIAMINE PENTAACETIC ACID|Diethylene triamine pentaacetic acid|DTPA|Penthanil|Detapac|Pentetic acid-containing product|Pentetic acid (substance)|Diethylenetriamine-N,N,N',N'',N''-pentaacetic Acid|Pentaacetic Acid, Diethylenetriamine|PENTETIC ACID|Diethylenetriamine Pentaacetic Acid|Pentetic acid|dtpa|Glycine, N,N-bis(2-(bis(carboxymethyl)amino)ethyl)-|Product containing pentetic acid (medicinal product)
pentetic acid
C0071598
Large enzyme complexes composed of a number of component enzymes that are found in STREPTOMYCES which biosynthesize MACROLIDES and other polyketides.
Polyketide Synthases|PKS enzyme|Synthases, Polyketide|polyketide synthase
polyketide synthase
C0026255
A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species.
Mitoses|mitosis|Mitosis|mitoses|Mitotic Process|Mitosis, function (observable entity)|karyokinesis|mitotic cycle|Mitosis, function
Mitosis
C1180334
Dyneins that are responsible for intracellular transport, MITOSIS, cell polarization, and movement within the cell.
Dyneins, Cytoplasmic|Cytoplasmic dynein
Cytoplasmic Dyneins
C1519624
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. [GOC:dph, GOC:jid]
membrane transport|transmembrane transport|Membrane Transport
Transmembrane Transport
C1566558
Any whole or part of a plant (including plant exudates), animal or microorganism that is unprocessed (raw material), or that has been processed, pulverized or extracted. Many of the natural products have some biological and/or pharmacological activity or are used for a specific purpose, not necessarily medicinal (food, aroma therapy, research and etc.). This class does not include any individual substance derived from plants/animals or other organisms with specific pharmacologic activity (See Drug, Natural Product).
natural products|product natural|Natural Product|Natural Products|naturals products|natural product
Natural Products
C1511625
The part of a transmembrane protein which projects into the cytoplasm.
Cytosolic Domain|Cytoplasmic Tail
Cytoplasmic Domain
C0072611
null
1-Oxa-2-azaspiro(4.5)deca-2,6,8-triene-3-carboxamide, N-(3-(4-(3-((2-(2-amino-1H-imidazol-4-yl)ethyl)amino)-2-(hydroxyimino)-3-oxopropyl)-2,6-dibromophenoxy)propyl)-7,9-dibromo-10-hydroxy-8-methoxy-, (5R-trans)-
purealin
C0910999
null
R-848|R 848|R848 compound
R 848
C0079488
A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).
Helicobacter pylori (organism)|Helicobacter pylori|Campylobacter pylori|helicobacter pylori bacteria|HELICOBACTER PYLORI|H. pylori|h. pylori|h pylori|helicobacter pylori organism|Helicobacter Pylori (diagnosis)|Campylobacter pylori subsp. pylori|Campylobacter pylori subsp pylori|Campylobacter pyloridis|helicobacter pylori|Helicobacter nemestrinae|campylobacter pylori|Hp - Helicobacter pylori
Helicobacter pylori
C0007028
A family of zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide. They play an important role in the transport of CARBON DIOXIDE from the tissues to the LUNG. EC 4.2.1.1.
Carbonate dehydratase|Carbonic Anhydrases|Anhydrases, Carbonic|Carbonic anhydrase|Carbonate hydro-lyase|Carbonate dehydratase (substance)|carbonic anhydrase|carbonate dehydratase|Carbonate Dehydratase|Dehydratase, Carbonate|Carbonic Anhydrase
CARBONATE DEHYDRATASE
C0854441
null
null
Gastric mucosa lesion
C0165590
An inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Distributed throughout many cells and tissues, various carbonic anhydrases play important roles in mineral and metabolic homeostasis. (NCI04)
4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda6-thieno[2,3-b]thiopyran-2-sulfonic acid amide|Dorzolamida|(4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide|Dorzolamid|Product containing dorzolamide (medicinal product)|Dorzolamide (substance)|(4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide|Dorzolamide|Dorzolamidum|dorzolamide|4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide|5,6-dihydro-4-ethylamino-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide|Dorzolamide-containing product|4S,6S-dorzolamide|4-ethylamino-5,6-dihydro-6-methyl-7,7-dioxide-4H-thieno(2,3-b)thiopyran-2-sulfonamide|DORZOLAMIDE
dorzolamide
C0043395
An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus. The severe form is characterized by fever, HEMOLYTIC JAUNDICE, and renal damage.
Yellow fever, unspecified|Yellow fever (disorder)|Yellow Fever|YELLOW FEVER|yellow fever|Fevers, Yellow|YF - Yellow fever|Yellow Fevers|Yellow fever, NOS|Yellow Fever Virus Infection|Fever, Yellow|Yellow fever
Yellow Fever
C0022262
Atomic species differing in mass number but having the same atomic number. (Grant & Hackh's Chemical Dictionary, 5th ed)
isotope|isotopes|Isotope, NOS|ISOTOPE|Isotope|Isotope (substance)|Isotopes
Isotopes
C0242377
Electromagnetic radiation in the portion of the spectrum from about 380 nm (violet) to 800 nm (red).
Visible Radiation|Visible Radiations|Visible light|Visible Light|Visible light radiation|Radiations, Visible|Radiation, Visible Light|visible light|Visible light, electromagnetic radiation|Radiation, Visible|Visible light, electromagnetic radiation (physical force)
Light, Visible
C0037638
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)
solvent|Solvent, NOS|Solvent|Solvents|Solvent (substance)|solvents
Solvents
C0260249
null
Infrared spectroscopy|infrared spectroscopy|Infrared spectroscopy technique (qualifier value)|Infrared spectroscopy technique
Infrared spectroscopy
C0013832
Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
Electrolyte (substance)|ELECTROLYTES|electrolytes|Electrolyte, NOS|Electrolytes|Electrolyte|electrolyte
Electrolytes
C0041095
Three individuals derived from three FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.
Triplet|triplet|Triplets|triplets
Triplet Multiple Birth
C0684021
null
conductors|conductor
conductor
C0542479
The capacity of a physical system to do work.
energies|energy in physics|energy|Energy
Energy, Physics
C0063090
null
Hydriodic acid|Hydrogen iodide|HYDRIODIC ACID|hydrogen iodide|HYDROGEN IODIDE|hydroiodic acid|Hydriodic acid (substance)|hydriodic acid
hydroiodic acid
C0931514
null
Helix of auricle of left ear|Left helix|Helical part of left pinna|Helix of left pinna
Left helix
C0206788
A benzoylhydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis.
Benzoylhydrazone Daunorubicin|(2S-cis)-Benzoic Acid[1-[4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3-naphthacenyl]ethylidene]hydrazide|zorubicin|Daunomycin Benzoylhydrazone|(2S-cis)-Benzoic Acid[1-[4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide|benzoic acid hydrazide 3-hydrazone with daunorubicin|benzoyl hydrazone daunorubicin|Zorubicin|Benzoyl Hydrazone Daunorubicin|(2S-cis)-benzoic acid[1-[4-[3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3-naphthacenyl]ethylidene]hydrazide|Zorubicine|Benzoic acid, (1-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1-,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide, (2S-cis)|daunomycin benzoylhydrazone|ZORUBICIN|Benzoic Acid Hydrazide 3-Hydrazone with Daunorubicin|RBZ|zorubicine
zorubicin
C0312864
null
Sensitised cell|Sensitized cell (finding)|Sensitized cell, NOS
Sensitized cell
C0260247
null
X ray spectroscopy|x-ray spectroscopy|X-ray spectroscopy
X-ray spectroscopy
C0055117
null
Cerium nitrate-containing product|Cerium nitrate|Product containing cerium nitrate (medicinal product)|Cerium nitrate (substance)
cerium nitrate
C0079837
A type of scanning probe microscopy in which a very sharp conducting needle is swept just a few angstroms above the surface of a sample. The tiny tunneling current that flows between the sample and the needle tip is measured, and from this are produced three-dimensional topographs. Due to the poor electron conductivity of most biological samples, thin metal coatings are deposited on the sample.
Microscopies, Scanning Tunneling|STM|Scanning Tunneling Microscopy|Scanning Tunneling Microscopies|Tunnelling Microscopies, Scanning|scanning tunneling microscopy|Microscopy, Scanning Tunnelling|Scanning tunneling microscopy|scanning tunneling microscopy (STM)|Microscopies, Scanning Tunnelling|Scanning Tunnelling Microscopy|Tunneling Microscopy, Scanning|Microscopy, Electron Scanning Tunnel|Tunneling Microscopies, Scanning|Microscopy, Scanning Tunneling|Scanning Tunnelling Microscopies|Tunnelling Microscopy, Scanning
Microscopy, Scanning Tunneling
C0145993
null
null
Titania
C0103202
null
anatase titanium dioxide
anatase
C0633261
null
null
AGGA
C0459800
A continuing periodic change in displacement with respect to a fixed reference. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Vibration - physical agent|Vibrations|Vibration|resonance|vibration|vibration [physical phenomenon]|Vibration (physical force)
Vibration - physical agent
C0048588
null
p-nitrophenyl acetate|para-nitrophenyl acetate
4-nitrophenyl acetate
C0040302
A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.
Titanium (substance)|Ti|titanium|Ti element|Titanium, NOS|Titanium Metallicum|TITANIUM|Titanium|Ti - Titanium
titanium
C0024947
One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.
Maxillary|Bone, Maxillary|Maxillas|Bones, Maxillary|upper jaw bone|maxillary|Maxillae|Maxillary Bones|Upper jaw bone|Upper Jaw|maxilla|MAXILLA|BONE, MAXILLA|Bone structure of maxilla (body structure)|Maxillary Bone|Maxilla|Maxilla bone structure|Maxilla, NOS|upper jaw|Bone structure of maxilla
Maxilla
C0004691
null
BALANOPOSTHITIS|Inflammation of penis and sheath|balanoposthitis|Balanoposthitis (disorder)|Balanoposthitis|Penis and prepuce inflamed|Inflammation of penis and prepuce|Penis and sheath inflamed
Balanoposthitis
C0399526
Malocclusion in which the mandible is anterior to the maxilla as reflected by the first relationship of the first permanent molar (mesioclusion).
angle class iii|Anterior occlusion|Enlarged mandible|Protrusive chin|'HAPSBURG JAW'|mandibular prognathism|Mandibular prognathia|Anteroclusion|Class III incisal relationship|Mandibular macrognathia|Lower jaw excess|Mandible prognathism|Prognathism, Mandibular|undershot jaw|Prognathia|Hyperplasia of lower jaw|Mandibular prognathism|Mandibular mesioclusion|Prominent lower jaw|Large lower jaw|Increased projection of lower jaw|Increased projection of mandible|Big lower jaw|anterior occlusion|Macromandible|Malocclusion, Angle's class III|Underbite|'HABSBURG JAW'|Prognathism|Malocclusion, Angle class III|Large mandible|Protrusive occlusion|Hapsburg Jaw|Malocclusion, class III|Prominent jaw|Big mandible|class iii malocclusion|Bulldog jaw|Mandibular prognathism (disorder)|Lower jaw hyperplasia|Malocclusion, Angle class III (disorder)|Malocclusion, Angle Class III|Class III malocclusion|Habsburg Jaw|Increased size of lower jaw|Enlargement of mandible|Relative mandibular prognathism|Prominent mandible|Undershot jaw|PROGNATHISM, MANDIBULAR|Prominent chin|Angle Class III
Class III malocclusion
C0913246
A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation.
Valdecoxib (substance)|Product containing valdecoxib (medicinal product)|Valdecoxib-containing product|4-(5-methyl-3-phenyl-isoxazol-4-yl)benzenesulfonamide|4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide|valdecoxib|VALDECOXIB|Valdecoxib
valdecoxib
C0913246
A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation.
Valdecoxib (substance)|Product containing valdecoxib (medicinal product)|Valdecoxib-containing product|4-(5-methyl-3-phenyl-isoxazol-4-yl)benzenesulfonamide|4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide|valdecoxib|VALDECOXIB|Valdecoxib
valdecoxib
C1514388
Treatment with analgesics on a schedule or in advance of the return of pain in an attempt to minimize peaks in the pain cycle.
null
Preemptive Analgesia
C0042285
A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
(2S)-2-Amino-3-methylbutanoic acid|Valine|L-(+)-alpha-Aminoisovaleric acid|(S)-2-Amino-3-methylbutanoic acid|valine (VAL)|Product containing valine (medicinal product)|valine|l-valine|2-Amino-3-methylbutyric acid|(S)-Valine|L Valine|L-alpha-Amino-beta-methylbutyric acid|Val|L-valin|L-Valine|Valine (substance)|VALINE|L-valine|Valine-containing product
valine
C0042285
A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
(2S)-2-Amino-3-methylbutanoic acid|Valine|L-(+)-alpha-Aminoisovaleric acid|(S)-2-Amino-3-methylbutanoic acid|valine (VAL)|Product containing valine (medicinal product)|valine|l-valine|2-Amino-3-methylbutyric acid|(S)-Valine|L Valine|L-alpha-Amino-beta-methylbutyric acid|Val|L-valin|L-Valine|Valine (substance)|VALINE|L-valine|Valine-containing product
valine
C0179407
null
bracketed|bracket
brackets
C0700351
An ear, nose, and throat bur is a device consisting of an interchangeable drill bit that is intended for use in an ear, nose, and throat electric or pneumatic surgical drill (Sec. 874.4250) for incising or removing bone in the ear, nose, or throat area. The bur consists of a carbide cutting tip on a metal shank or a coating of diamond on a metal shank. The device is used in mastoid surgery, frontal sinus surgery, and surgery of the facial nerves.
burs|Bur (physical object)|medical bur|Bur|bur|BUR|BURR
Burs - medical device
C0179038
Any device designed to perform an analysis.
Analysers|analyzer|Analyzer, device|analyzers|Analyzer, NOS|analyser|Analyser|Analyzer Device|Analyzer, device (physical object)|Analyzer
Analyzer, device
C0036088
A solution used for irrigating the mouth in xerostomia and as a substitute for saliva.
Saliva, Artificial|saliva substitutes|artificial salivas|SALIVA, ARTIFICIAL|artificial saliva|Artificial saliva|Medicinal product acting as artificial saliva (product)|saliva substitute|ARTIFICIAL SALIVA|Artificial saliva agent|Artificial Saliva|Artificial saliva (physical object)|SALIVA,ARTIFICIAL
Artificial saliva
C0086651
A rare autosomal recessive lysosomal storage disease caused by deficiency of the enzyme galactosamine-6-sulfatase. It is characterized by skeletal and central nervous system deficits.
Deficiency of chondroitinsulphatase|MPS IV A|Deficiency of N-acetylgalactosamine-6-sulfatase|Galactosamine 6 Sulfatase Deficiency|Galactose-6-sulfatase deficiency|Morquio A Disease|Disease, Morquio A|Mucopolysaccharidosis Type IVA|Deficiency of N-acetylgalactosamine-6-sulphatase|GALACTOSAMINE-6-SULFATASE DEFICIENCY|N-acetylgalactosamine-6-sulfatase deficiency|MUCOPOLYSACCHARIDOSIS, TYPE IVA|GALNS DEFICIENCY|Mucopolysaccharidosis, MPS-IV-A|MORQUIO A DISEASE|Morquio A syndrome|Deficiency, Galactosamine-6-Sulfatase|Morquio syndrome A|Deficiency of chondroitinase|MPS4A|Morquio Syndrome A|Mucopolysaccharidosis IV-A|Deficiency of N-acetylgalactosamine-6-sulfatase (finding)|Galactosamine-6-sulfatase deficiency|mps iv|MORQUIO SYNDROME A|Galactosamine-6-sulphatase deficiency|Morquio's syndrome, classic form|Mucopolysaccharidosis IV-A (disorder)|MPS IV-A-Mucopolysaccharidosis IV-A|Deficiencies, Galactosamine-6-Sulfatase|N-acetylgalactosamine-6-sulphatase deficiency|Deficiency of chondroitinsulfatase|MPS IVA|Deficiency of galactose-6-sulphate sulphatase|Syndrome A, Morquio|Galactose-6-sulphatase deficiency|Galactosamine-6-Sulfatase Deficiencies|Deficiency of galactose-6-sulfate sulfatase|Mucopolysaccharidosis Type IV A|Galactosamine-6-Sulfatase Deficiency
Mucopolysaccharidosis, MPS-IV-A
C0026707
Genetic disorder of mucopolysaccharide metabolism characterized by skeletal abnormalities, joint instability, development of cervical myelopathy, and excessive urinary keratan sulfate. There are two biochemically distinct forms, each due to a deficiency of a different enzyme.
Eccentroosteochondrodysplasia|Type IV, Mucopolysaccharidosis|morquio's syndrome|Morquio Syndromes|Brailsford-Morquio syndrome|MORQUIO-ULLRICH SYNDROME|MORQUIO SYNDROME|Morquio Disease|Morquio Syndrome|Syndrome, Morquio's|Hereditary enchondral dysostosis|spondylo-epiphyseal dysplasia|Morquio syndrome (disorder)|Eccentro-Osteochondrodysplasia|Morquio-Suarez syndrome|Mucopolysaccharidosis, type IV (MPS IV)|eccentroosteochondrodysplasia|Morquio syndrome, NOS|Syndrome, Morquio|chondroosteodystrophy|KERATANSULFATURIA|MUCOPOLYSACCHARIDOSIS IV|Morquio disease|Eccentro-Osteochondrodysplasias|Morquio-Ullrich disease|Mucopolysaccharidosis Type IV|mucopolysaccharidosis type IV|MORQUIO-BRAILSFORD SYNDROME|Morquio's Disease|Keratan sulphaturia|Disease, Morquio's|Morquio-Brailsford disease|Mucopolysaccharidosis, MPS-IV|Eccentroosteochondrodysplasias|Keratan sulfaturia|OSTEOCHONDRODYSTROPHY DEFORMANS, HEREDITARY|Morquio's Syndrome|Morquios Syndrome|Mucopolysaccharidosis IV|Eccentro Osteochondrodysplasia|Mucopolysaccharidosis type IV|Mucopolysaccharidosis Type IVs|osteochondrodysplasia|morquios syndrome|Familial osseous dystrophy|morquio disease|Mucopolysaccharidosis 4|Morquio disease, NOS|Morquio syndrome|Familial osteochondrodystrophy|IV, Mucopolysaccharidosis Type|syndrome morquio's|Morquios Disease|osteochondrodystrophy|Chondrodystrophia tarda|IVs, Mucopolysaccharidosis Type|Osteochondrodystrophia deformans|Type IVs, Mucopolysaccharidosis|Morquio's syndrome|Syndromes, Morquio|Chondro-osteodystrophy|morquio syndrome|morquio's disease|Osteochondrodystrophy|Atypical chondrodystrophy|Disease, Morquio
Mucopolysaccharidosis IV
C0026707
Genetic disorder of mucopolysaccharide metabolism characterized by skeletal abnormalities, joint instability, development of cervical myelopathy, and excessive urinary keratan sulfate. There are two biochemically distinct forms, each due to a deficiency of a different enzyme.
Eccentroosteochondrodysplasia|Type IV, Mucopolysaccharidosis|morquio's syndrome|Morquio Syndromes|Brailsford-Morquio syndrome|MORQUIO-ULLRICH SYNDROME|MORQUIO SYNDROME|Morquio Disease|Morquio Syndrome|Syndrome, Morquio's|Hereditary enchondral dysostosis|spondylo-epiphyseal dysplasia|Morquio syndrome (disorder)|Eccentro-Osteochondrodysplasia|Morquio-Suarez syndrome|Mucopolysaccharidosis, type IV (MPS IV)|eccentroosteochondrodysplasia|Morquio syndrome, NOS|Syndrome, Morquio|chondroosteodystrophy|KERATANSULFATURIA|MUCOPOLYSACCHARIDOSIS IV|Morquio disease|Eccentro-Osteochondrodysplasias|Morquio-Ullrich disease|Mucopolysaccharidosis Type IV|mucopolysaccharidosis type IV|MORQUIO-BRAILSFORD SYNDROME|Morquio's Disease|Keratan sulphaturia|Disease, Morquio's|Morquio-Brailsford disease|Mucopolysaccharidosis, MPS-IV|Eccentroosteochondrodysplasias|Keratan sulfaturia|OSTEOCHONDRODYSTROPHY DEFORMANS, HEREDITARY|Morquio's Syndrome|Morquios Syndrome|Mucopolysaccharidosis IV|Eccentro Osteochondrodysplasia|Mucopolysaccharidosis type IV|Mucopolysaccharidosis Type IVs|osteochondrodysplasia|morquios syndrome|Familial osseous dystrophy|morquio disease|Mucopolysaccharidosis 4|Morquio disease, NOS|Morquio syndrome|Familial osteochondrodystrophy|IV, Mucopolysaccharidosis Type|syndrome morquio's|Morquios Disease|osteochondrodystrophy|Chondrodystrophia tarda|IVs, Mucopolysaccharidosis Type|Osteochondrodystrophia deformans|Type IVs, Mucopolysaccharidosis|Morquio's syndrome|Syndromes, Morquio|Chondro-osteodystrophy|morquio syndrome|morquio's disease|Osteochondrodystrophy|Atypical chondrodystrophy|Disease, Morquio
Mucopolysaccharidosis IV
C0204193
A dental treatment to correct malocclusions of the teeth and their surrounding structures.
Orthodontic procedure (procedure)|ORTHODONTIC PROCEDURES|Orthodon Procedure|orthodontics treatment|Orthodontic Treatment|Orthodontic procedure, NOS|orthodontic treatment|Orthodontic procedure|Orthodontics
Orthodontic procedure
C1268545
null
J wire, device|J wire, device (physical object)
J wire
C0018544
A family of nonmetallic, generally electronegative, elements that form group 17 (formerly group VIIa) of the periodic table.
Halogens|Halogen|halogens|Group 17 Elements|halogen elements|Elements, Group 17|halogen|Halogen, NOS|Halogen (substance)
Halogens
C0263680
null
Chronic arthritis|Chronic arthritis (disorder)|chronic arthritis|arthritis chronic
Chronic arthritis
C0524975
Bone lengthening by gradual mechanical distraction. An external fixation device produces the distraction across the bone plate. The technique was originally applied to long bones but in recent years the method has been adapted for use with mandibular implants in maxillofacial surgery.
Osteogeneses, Distraction|Distraction Osteogeneses|osteogenesis distraction|distraction osteogenesis|Distraction Osteogenesis
Osteogenesis, Distraction
C0683474
It is a client-centered, directive method for eliciting intrinsic motivation to change using open-ended questions, reflective listening, and decisional balancing. This nonjudgmental, nonconfrontational interviewing style is designed to minimize a patient's resistance to change by creating an interaction that supports open discussion of risky or problem behavior.
motivational interviewing|Motivational Interviewing Intervention|Motivational interviewing (qualifier value)|Motivational Interviewing|MI|Interviewing, Motivational|Motivational interviewing|motivational interview|motivational enhancement therapy|motivational counseling
Motivational Interviewing
C0814459
null
brief intervention|brief interventions
brief intervention
C0003461
The lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded.
ANUS|Anal structure (body structure)|Anal structure|anus|Anus|Ano-|Anal orifice|anal|Anus, NOS|LARGE INTESTINE, ANUS|Anal
Anus
C0556025
null
Injecting drug user (finding)|IDU - Injecting drug user|injection drug user|drug injecting users|drug injection users|Drug injector
Injecting drug user
C0849912
Excessively affected by emotion.
emotional|Emotional|Emotional (qualifier value)
Emotional
C0237154
Without a stable or permanent residence.
homelessness|Homelessness|Housing lack (finding)|Homeless|homeless|Living on the street|Homeless (finding)|Housing lack
Homelessness
C0021708
Hospital units providing continuous surveillance and care to acutely ill patients.
INTENSIVE CARE UNIT|Intensive Care Units|Intensive Care Unit|ICU|Intensive care unit|ITU|intensive care unit (ICU)|ICU - Intensive care unit|care intensive units|intensive care unit|i c u|Care Units, Intensive|critical care unit|Intensive care unit (environment)|care critical unit|care critical units|Critical Care Unit|Unit, Intensive Care|i.c.u.|intensive care units|Intensive care units|care intensive unit|Care Unit, Intensive|Units, Intensive Care|CRITICAL CARE UNIT
intensive care unit
C0009421
A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Coma|Comas|COMA (NOS)|coma|exanimation|Coma (disorder)|comatose|Comatose|COMA|Coma, NOS|Exanimation
Comatose
C0008651
A specific pair of human chromosomes in group A (CHROMOSOMES, HUMAN, 1-3) of the human chromosome classification.
chromosome 1|Chromosome pair 1 (cell structure)|1 chromosome|1 chromosomes|Chromosome 1|chromosome pair 1|Chromosome pair 1
Chromosomes, Human, Pair 1
C0752063
Microbodies which occur in animal and plant cells and in certain fungi and protozoa. They contain peroxidase, catalase, and allied enzymes. (From Singleton and Sainsbury, Dictionary of Microbiology and Molecular Biology, 2nd ed)
Peroxisome|peroxisomes|peroxisome|Peroxysoma|Peroxisomes|Microbody|Peroxysome
peroxisome
C1021171
null
Dendrocalamopsis oldhamii|Dendrocalamopsis oldhami
Bambusa oldhamii
C0038817
Irradiation directly from the sun.
Sunshine|Light emitted by the sun|Sun|Solar energy|sunlight|Light emitted by the sun (physical force)|Sunlight
Sunlight
C1045267
null
null
Russula brevipes
C0917892
The fluctuation of the ALLELE FREQUENCY from one generation to the next.
Drift, Genetic|Genetic Divergence|genetic drift|Genetic Differentiation|Genetic Drift|drifts genetic
Genetic Drift
C0008670
A specific pair of GROUP C CHROMOSOMES of the human chromosome classification.
Chromosome 7|chromosome 7|7 chromosome|Chromosome pair 7 (cell structure)|Chromosome pair 7
Chromosomes, Human, Pair 7
C0376297
The cessation of life due to heart abnormalities or disease.
cardiac death|Death, Cardiac|cardiac deaths|Cardiac Death
Cardiac Death
C0242231
Narrowing or constriction of a coronary artery.
artery coronary stenosis|Coronary Stenoses|Narrowing of coronary artery|Coronary arteries--Stenosis|Artery Stenoses, Coronary|Coronary artery stenosis|Coronary Artery Stenosis|Stenoses, Coronary|Coronary Artery Stenoses|Stenosis, Coronary Artery|Stenosis, Coronary|Artery Stenosis, Coronary|stenosis coronary|Narrow coronary arteries|Stenoses, Coronary Artery|coronary artery stenosis|coronary stenosis|Coronary artery stenosis (disorder)
Coronary Stenosis
C1562036
Compounds that inhibit or block the PHOSPHATASE activity of CALCINEURIN.
Substance with calcineurin inhibitor mechanism of action|Calcineurin Blockers|Product containing calcineurin inhibitor (product)|Protein Phosphatase 3 Inhibitors|Substance with calcineurin inhibitor mechanism of action (substance)|Protein Phosphatase-2B Inhibitors|Calcineurin Inhibitors|CNI Inhibitor|Calcineurin inhibitor-containing product|Calcineurin Antagonists|Calcineurin inhibitor|Calcineurin inhibitors|Protein Phosphatase 2B Inhibitors
Calcineurin inhibitor
C0260039
A doctor who specializes in diagnosing and treating kidney disease.
nephrologists|Nephrologist (occupation)|Nephrologists|Nephrologist|nephrologist
Nephrologists
C0227616
The fibrous connective tissue that surrounds each kidney.
Capsula fibrosa renis|Structure of fibrous capsule of kidney|Capsule of kidney|Gerota's capsule|renal capsule|Structure of capsule of kidney (body structure)|gerota's fascia|Renal capsule|Fascia renalis|Structure of fibrous capsule of kidney (body structure)|kidney capsule|Capsule of kidney, NOS|Fascia of Zuckerkandl|fascia renal|Gerota's fascia|Renal fascia|capsule kidney|Fibrous capsule of kidney|Structure of capsule of kidney|Renal Capsule
Fibrous capsule of kidney
C0070410
A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.
Lymphocyte Pore-Forming Protein|perforin|Perforin|Pore-Forming Protein, Lymphocyte|Cytolysin|Lymphocyte Pore Forming Protein|Perforin (substance)|Perforin 1
perforin
C0085149
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
Tacrolimus-containing product|15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, (3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*))-|tacrolimus|Product containing tacrolimus (medicinal product)|Tacrolimus|TACROLIMUS|Tacrolimus (substance)|hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone|Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
tacrolimus
C0962934
null
null
PG490-88
C0085149
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
Tacrolimus-containing product|15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, (3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*))-|tacrolimus|Product containing tacrolimus (medicinal product)|Tacrolimus|TACROLIMUS|Tacrolimus (substance)|hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone|Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
tacrolimus
C0021756
A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes.
Interleukin-2-containing product|Product containing interleukin-2 (medicinal product)|Interleukin 2|IL2 Protein|Interleukin 2 Precursor|ETAF|T Cell Stimulating Factor|il-2|Lymphocyte Mitogenic Factor|T-stimulating factor|interleukin ii|Interleukin II|INTERLEUKIN-2|T cell growth factor|Mitogenic Factor, Lymphocyte|T-Cell Stimulating Factor|Lymphocyte blastogenic factor|TSF (thymocyte stimulating factor)|co-stimulator|il2|IL2|il 2|tsf|costimulator|interleukin 2|Mitogenic Factor|TSF|T-Cell Growth Factor|Interleukin-2 (substance)|TCGF (T cell growth factor)|T Cell Growth Factor|Interleukine 2|TCGF|Thymocyte Stimulating Factor|Epidermal Thymocyte Activating Factor|IL-2|Interleukin-2|interleukin-2|Lymphocyte mitogenic factor
Interleukin-2
C0384648
A proinflammatory cytokine produced primarily by T-LYMPHOCYTES or their precursors. Several subtypes of interleukin-17 have been identified, each of which is a product of a unique gene.
Interleukin-17|Interleukin 17|CTLA-8|IL-17
Interleukin-17
C0221277
A lymphocyte that may be irregular or not conforming to type.
atypical lymphocytes|lymphocyte atypical|LYMPHOCYTES ATYPICAL|Atypical lymphocyte (morphologic abnormality)|Atypical Lymphocyte|atypical lymphocyte|Abnormality of cells of the lymphoid lineage|Abnormal lymphocytes|Atypical lymphocyte|Abnormal lymphocyte morphology|Atypical lymphocytes
Atypical lymphocyte
C0403592
Gradual loss of donor kidney function occurring months to years after transplantation. It is characterized by renal tubular atrophy, interstitial fibrosis, and arterial wall thickening.
CAN|Chronic Allograft Nephropathy|Chronic rejection of renal transplant (disorder)|Chronic transplant nephropathy|Chronic rejection of renal transplant|Chronic Kidney Allograft Nephropathy
Chronic rejection of renal transplant
C0877042
null
loss graft
graft loss
C0677960
Treatment to destroy T cells, which play an important role in the immune response. Elimination of T cells from a bone marrow graft or peripheral blood stem cell graft from a donor may reduce the chance of an immune reaction against the recipient's tissues.
T-Cell Depletion|T lymphocyte depletion therapy|T-cell depletion|T-Cell Depletion Therapy|T-Lymphocyte Depletion Therapy
T-Cell Depletion Therapy
C0730920
null
Thymoglobuline|Thymoglobulin|thymoglobulin|thymoglobuline
Thymoglobulin
C0730920
null
Thymoglobuline|Thymoglobulin|thymoglobulin|thymoglobuline
Thymoglobulin
C0022671
The transference of a kidney from one human or animal to another.
Transplant of kidney, NOS|Kidney transplant|Renal graft|renal transplantation|Tx - Renal transplantation|Transplantation of kidney|kidney transplanted|renal transplant|kidneys transplant|Kidney Grafting|KIDNEY: TRANSPLANTATIONS AND TRANSPOSITIONS|Renal Transplantation|Transplantation, Renal|Renal transplant, NOS|kidney transplant|Transplant of kidney|kidney transplantation|Kidney Transplantation|kidneys transplants|Renal Transplantations|renal transplants|kidney transplantation procedure|Transplant of kidney (procedure)|renal graft|Transplantations, Kidney|Kidneys--Transplantation|kidney transplants|Kidney Transplant|Kidney transplantation, NOS|kidney transplant procedure|Transplantations, Renal|KIDNEY TRANSPLANT|Kidney transplantation|Renal transplant|Tx - Kidney transplantation|Grafting, Kidney|Renal transplantation|Transplantation, Kidney|Kidney Transplantations
Kidney Transplantation
C0078988
A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam. (OMB)
Asian|Asian race|ASIAN|ORIENTAL|oriental|RaceAsian|Asian race (racial group)|Oriental (ethnic group)|Oriental|asians|orientals|Asians
Asians
C1142985
An azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe appears to interact physically with cholesterol transporters at the brush border of the small intestine and inhibits the intestinal absorption of cholesterol and related phytosterols. As a result, ezetimibe causes a decrease in the level of blood cholesterol or an increase in the clearance of cholesterol from the bloodstream. Overall, the following effects observed are a reduction of hepatic cholesterol stores and a reduction of total cholesterol, LDL cholesterol, and other triglycerides in the blood.
Ezetimibe-containing product|Ezetimib|ezetimibe|EZETIMIBE|ezetimib|ézétimibe|(1-(4-fluorophenyl)-(3R)-(3-(4-fluorophenyl)-(3S)-hydroxypropyl)-(4S)-(4-hydroxyphenyl)-2-azetidinone)|1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone|Ezetimibum|Product containing ezetimibe (medicinal product)|Ezetimibe|Ezetimibe (substance)|Ezetimiba
ezetimibe
C0054450
A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes.
Protein Phosphatase 3|Protein Phosphatase 2B|Phosphatase 3, Protein|Protein Phosphatase-2B|calcineurin|Calcineurin|Protein phosphatase 3|Protein phosphatase 3 (substance)
Calcineurin
C0360714
Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
Statin|Inhibitors, Hydroxymethylglutaryl Coenzyme A|hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-COA REDUCTASE INHIBITORS|Hydroxymethylglutaryl-CoA Inhibitors|Inhibitors, Hydroxymethylglutaryl-CoA|Inhibitors, Hydroxymethylglutaryl-CoA Reductase|HMG CoA Reductase Inhibitors|Statin-containing product|Statins|Inhibitors, HMG-CoA Reductase|HMG-CoA reductase inhibitor|Statins, HMG CoA|HMG-CoA Reductase Inhibitor|Hydroxymethylglutaryl-Coenzyme A Inhibitors|Reductase Inhibitors, HMG-CoA|HMG-CoA reductase inhibitors|HMG-CoA Reductase Inhibitors|Substance with 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor mechanism of action (substance)|statin|HMG-CoA reductase inhibitor, NOS|Inhibitors, Hydroxymethylglutaryl-Coenzyme A|Reductase Inhibitors, Hydroxymethylglutaryl-CoA|Statins, HMG-CoA|Hydroxymethylglutaryl CoA Reductase Inhibitors|Inhibitors, HMG CoA Reductase|HMG-CoA reductase inhibitor-containing product|Hydroxymethylglutaryl-CoA Reductase Inhibitors|HMG-CoA Statins|Product containing 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (product)|Inhibitors, Hydroxymethylglutaryl CoA|Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors
Hydroxymethylglutaryl-CoA Reductase Inhibitors