File size: 1,406 Bytes
bd35344 dcf7281 bd35344 dcf7281 da22be5 |
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 |
---
dataset_info:
features:
- name: vh
dtype: string
- name: vl
dtype: string
- name: label
dtype:
class_label:
names:
'0': non-binder
'1': binder
splits:
- name: train
num_bytes: 4428189
num_examples: 18223
- name: eval
num_bytes: 553554
num_examples: 2278
- name: test
num_bytes: 553554
num_examples: 2278
download_size: 415916
dataset_size: 5535297
---
# HER2 binding dataset
HER2 binding antibodies have been obtained from the [Github repo](https://github.com/dahjan/DMS_opt) for [Mason et al. (2021)](https://www.nature.com/articles/s41551-021-00699-9).
Labels for antibody sequences were generated using scripts in the above Github repo. The number of negatives and positives were balanced through random undersampling using [imbalanced-learn](https://github.com/scikit-learn-contrib/imbalanced-learn), and sequences were deduplicated.
The dataset has:
* 39108 antibodies in total
* 22779 antibodies after undersampling and deduplication
* 18223 in the training set, 2278 in the evaluation set, and 2278 in the test set.
Example
| vh_full | vl_full | label |
| ------- | ------- | ----- |
| EVQ... | DIQ... | 1 |
| EVQ... | DIQ... | 0 |
| EVQ... | DIQ... | 0 |
| EVQ... | DIQ... | 1 |
References
* [Mason et al. (2021) paper](https://www.nature.com/articles/s41551-021-00699-9)
|