text: Lucinactant has been shown to improve pulmonary gas exchange and mechanics in RDS; in particular, its effects have been compared to an animal-derived surfactant preparation in premature lambs.(28) In MAS, only one experimental study has prospectively compared the administration of lucinactant by bolus or by lavage,(11) showing better results in the dilute surfactant lavage group, but it was performed in adult rabbits, not in juvenile animals.