string: …subunits (Megee et al. 1999; Tanaka et al. 1999) and Cac1 (Sharp et al. 2002) are distributed across ~10 kb of centromeric chromatin; in contrast, the centromere-specific histone Cse4 and the CENP-C homolog Mif2 are tightly localized over only the 125 bp core centromeric DNA (Meluh et al. 1998).