string: The rapid disappearance of cyclin mRNA after RNAi treatment is consistent with the currently-held notion that dsRNA targets the gene-specific destruction of mRNA in a wide variety of eukaryotic cells (Fire et al., 1998; Tabara et al., 1998; Tabara et al., 1999; Sanchez-Alvorado and Newmark, 1999; Grishok et al., 2000; Boscher and Labouesse, 2000; Klink and Wolniak, 2000).