[{"audio_id": "caQeszpDOc0", "text": {"caQeszpDOc0-00000-00000010-00000457": "WITH AJ FELDMAN.", "caQeszpDOc0-00001-00000457-00000463": "WITH AJ FELDMAN.", "caQeszpDOc0-00002-00000463-00000640": "WITH AJ FELDMAN. >> AJ: THE RED LAKE GIRLS", "caQeszpDOc0-00003-00000640-00000647": "WITH AJ FELDMAN. >> AJ: THE RED LAKE GIRLS", "caQeszpDOc0-00004-00000647-00000714": "WITH AJ FELDMAN. >> AJ: THE RED LAKE GIRLS BASKETBALL TEAM MADE IT TO THE", "caQeszpDOc0-00005-00000714-00000720": ">> AJ: THE RED LAKE GIRLS BASKETBALL TEAM MADE IT TO THE", "caQeszpDOc0-00006-00000720-00000787": ">> AJ: THE RED LAKE GIRLS BASKETBALL TEAM MADE IT TO THE STATE TOURNAMENT FOR THE FIRST", "caQeszpDOc0-00007-00000787-00000794": "BASKETBALL TEAM MADE IT TO THE STATE TOURNAMENT FOR THE FIRST", "caQeszpDOc0-00008-00000794-00000967": "BASKETBALL TEAM MADE IT TO THE STATE TOURNAMENT FOR THE FIRST TIME IN SCHOOL HISTORY TWO YEARS", "caQeszpDOc0-00009-00000967-00000974": "STATE TOURNAMENT FOR THE FIRST TIME IN SCHOOL HISTORY TWO YEARS", "caQeszpDOc0-00010-00000974-00001020": "STATE TOURNAMENT FOR THE FIRST TIME IN SCHOOL HISTORY TWO YEARS AGO.", "caQeszpDOc0-00011-00001020-00001027": "TIME IN SCHOOL HISTORY TWO YEARS AGO.", "caQeszpDOc0-00012-00001027-00001161": "TIME IN SCHOOL HISTORY TWO YEARS AGO. AFTER A HIATUS LAST YEAR, THE", "caQeszpDOc0-00013-00001161-00001167": "AGO. AFTER A HIATUS LAST YEAR, THE", "caQeszpDOc0-00014-00001167-00001297": "AGO. AFTER A HIATUS LAST YEAR, THE WARRIORS ARE BACK IN THE BIG", "caQeszpDOc0-00015-00001297-00001304": "AFTER A HIATUS LAST YEAR, THE WARRIORS ARE BACK IN THE BIG", "caQeszpDOc0-00016-00001304-00001488": "AFTER A HIATUS LAST YEAR, THE WARRIORS ARE BACK IN THE BIG DANCE AND READY TO MAKE RED LAKE", "caQeszpDOc0-00017-00001488-00001494": "WARRIORS ARE BACK IN THE BIG DANCE AND READY TO MAKE RED LAKE", "caQeszpDOc0-00018-00001494-00001551": "WARRIORS ARE BACK IN THE BIG DANCE AND READY TO MAKE RED LAKE PROUD.", "caQeszpDOc0-00019-00001551-00001558": "DANCE AND READY TO MAKE RED LAKE PROUD.", "caQeszpDOc0-00020-00001558-00001634": "DANCE AND READY TO MAKE RED LAKE PROUD. >> HAVING ALREADY LOST TO THEM", "caQeszpDOc0-00021-00001634-00001641": "PROUD. >> HAVING ALREADY LOST TO THEM", "caQeszpDOc0-00022-00001641-00001875": "PROUD. >> HAVING ALREADY LOST TO THEM THIS SEASON, RED LAKE WAS", "caQeszpDOc0-00023-00001875-00001881": ">> HAVING ALREADY LOST TO THEM THIS SEASON, RED LAKE WAS", "caQeszpDOc0-00024-00001881-00002011": ">> HAVING ALREADY LOST TO THEM THIS SEASON, RED LAKE WAS DEFINITELY THE UNDERDOG IN THE", "caQeszpDOc0-00025-00002011-00002018": "THIS SEASON, RED LAKE WAS DEFINITELY THE UNDERDOG IN THE", "caQeszpDOc0-00026-00002018-00002225": "THIS SEASON, RED LAKE WAS DEFINITELY THE UNDERDOG IN THE SECTION CHAMPIONSHIP GAME", "caQeszpDOc0-00027-00002225-00002232": "DEFINITELY THE UNDERDOG IN THE SECTION CHAMPIONSHIP GAME", "caQeszpDOc0-00028-00002232-00002362": "DEFINITELY THE UNDERDOG IN THE SECTION CHAMPIONSHIP GAME AGAINST 12th RANKED STEVEN", "caQeszpDOc0-00029-00002362-00002369": "SECTION CHAMPIONSHIP GAME AGAINST 12th RANKED STEVEN", "caQeszpDOc0-00030-00002369-00002502": "SECTION CHAMPIONSHIP GAME AGAINST 12th RANKED STEVEN ARGYLE, BUT THE WARRIORS CAME", "caQeszpDOc0-00031-00002502-00002509": "AGAINST 12th RANKED STEVEN ARGYLE, BUT THE WARRIORS CAME", "caQeszpDOc0-00032-00002509-00002605": "AGAINST 12th RANKED STEVEN ARGYLE, BUT THE WARRIORS CAME TOGETHER AND PLAYED ARGUABLY", "caQeszpDOc0-00033-00002605-00002612": "ARGYLE, BUT THE WARRIORS CAME TOGETHER AND PLAYED ARGUABLY", "caQeszpDOc0-00034-00002612-00002819": "ARGYLE, BUT THE WARRIORS CAME TOGETHER AND PLAYED ARGUABLY THEIR BEST GAME OF THE SEASON.", "caQeszpDOc0-00035-00002819-00002826": "TOGETHER AND PLAYED ARGUABLY THEIR BEST GAME OF THE SEASON.", "caQeszpDOc0-00036-00002826-00002959": "TOGETHER AND PLAYED ARGUABLY THEIR BEST GAME OF THE SEASON. >> I KNEW THAT WE COULD BEAT", "caQeszpDOc0-00037-00002959-00002966": "THEIR BEST GAME OF THE SEASON. >> I KNEW THAT WE COULD BEAT", "caQeszpDOc0-00038-00002966-00003069": "THEIR BEST GAME OF THE SEASON. >> I KNEW THAT WE COULD BEAT THEM SINCE THE BEGINNING OF THE", "caQeszpDOc0-00039-00003069-00003076": ">> I KNEW THAT WE COULD BEAT THEM SINCE THE BEGINNING OF THE", "caQeszpDOc0-00040-00003076-00003239": ">> I KNEW THAT WE COULD BEAT THEM SINCE THE BEGINNING OF THE SEASON, BECAUSE ALL OF THESE", "caQeszpDOc0-00041-00003239-00003246": "THEM SINCE THE BEGINNING OF THE SEASON, BECAUSE ALL OF THESE", "caQeszpDOc0-00042-00003246-00003336": "THEM SINCE THE BEGINNING OF THE SEASON, BECAUSE ALL OF THESE GIRLS HAVE THE TALENT TO BEAT", "caQeszpDOc0-00043-00003336-00003343": "SEASON, BECAUSE ALL OF THESE GIRLS HAVE THE TALENT TO BEAT", "caQeszpDOc0-00044-00003343-00003496": "SEASON, BECAUSE ALL OF THESE GIRLS HAVE THE TALENT TO BEAT THEM AND NO TEAM IS UNBEATABLE.", "caQeszpDOc0-00045-00003496-00003503": "GIRLS HAVE THE TALENT TO BEAT THEM AND NO TEAM IS UNBEATABLE.", "caQeszpDOc0-00046-00003503-00003743": "GIRLS HAVE THE TALENT TO BEAT THEM AND NO TEAM IS UNBEATABLE. >> IT'S REALLY NICE KNOWING THAT", "caQeszpDOc0-00047-00003743-00003750": "THEM AND NO TEAM IS UNBEATABLE. >> IT'S REALLY NICE KNOWING THAT", "caQeszpDOc0-00048-00003750-00003933": "THEM AND NO TEAM IS UNBEATABLE. >> IT'S REALLY NICE KNOWING THAT I'VE PLAYED WITH THESE GIRLS", "caQeszpDOc0-00049-00003933-00003940": ">> IT'S REALLY NICE KNOWING THAT I'VE PLAYED WITH THESE GIRLS", "caQeszpDOc0-00050-00003940-00004150": ">> IT'S REALLY NICE KNOWING THAT I'VE PLAYED WITH THESE GIRLS SINCE ELEMENTARY AND WE FINALLY", "caQeszpDOc0-00051-00004150-00004157": "I'VE PLAYED WITH THESE GIRLS SINCE ELEMENTARY AND WE FINALLY", "caQeszpDOc0-00052-00004157-00004561": "I'VE PLAYED WITH THESE GIRLS SINCE ELEMENTARY AND WE FINALLY MADE IT THIS FAR.", "caQeszpDOc0-00053-00004561-00004567": "SINCE ELEMENTARY AND WE FINALLY MADE IT THIS FAR.", "caQeszpDOc0-00054-00004567-00004714": "SINCE ELEMENTARY AND WE FINALLY MADE IT THIS FAR. >> THEY AVENGED LAST YEAR'S LOSS", "caQeszpDOc0-00055-00004714-00004721": "MADE IT THIS FAR. >> THEY AVENGED LAST YEAR'S LOSS", "caQeszpDOc0-00056-00004721-00004851": "MADE IT THIS FAR. >> THEY AVENGED LAST YEAR'S LOSS IN THE CHAMPIONSHIP GAME.", "caQeszpDOc0-00057-00004851-00004858": ">> THEY AVENGED LAST YEAR'S LOSS IN THE CHAMPIONSHIP GAME.", "caQeszpDOc0-00058-00004858-00005111": ">> THEY AVENGED LAST YEAR'S LOSS IN THE CHAMPIONSHIP GAME. >> PRESSURE ON THE BALL, GETTING", "caQeszpDOc0-00059-00005111-00005118": "IN THE CHAMPIONSHIP GAME. >> PRESSURE ON THE BALL, GETTING", "caQeszpDOc0-00060-00005118-00005265": "IN THE CHAMPIONSHIP GAME. >> PRESSURE ON THE BALL, GETTING OPEN, SCARE THEM A LITTLE BIT.", "caQeszpDOc0-00061-00005265-00005271": ">> PRESSURE ON THE BALL, GETTING OPEN, SCARE THEM A LITTLE BIT.", "caQeszpDOc0-00062-00005271-00005518": ">> PRESSURE ON THE BALL, GETTING OPEN, SCARE THEM A LITTLE BIT. >> THEY CAME TOGETHER AS A CREW,", "caQeszpDOc0-00063-00005518-00005525": "OPEN, SCARE THEM A LITTLE BIT. >> THEY CAME TOGETHER AS A CREW,", "caQeszpDOc0-00064-00005525-00005695": "OPEN, SCARE THEM A LITTLE BIT. >> THEY CAME TOGETHER AS A CREW, AND THEY WANTED IT MORE THAN", "caQeszpDOc0-00065-00005695-00005702": ">> THEY CAME TOGETHER AS A CREW, AND THEY WANTED IT MORE THAN", "caQeszpDOc0-00066-00005702-00006042": ">> THEY CAME TOGETHER AS A CREW, AND THEY WANTED IT MORE THAN STEVEN ARGYLE WANTED IT.", "caQeszpDOc0-00067-00006042-00006049": "AND THEY WANTED IT MORE THAN STEVEN ARGYLE WANTED IT.", "caQeszpDOc0-00068-00006049-00006159": "AND THEY WANTED IT MORE THAN STEVEN ARGYLE WANTED IT. >> AJ: THEY'LL NEED ANOTHER", "caQeszpDOc0-00069-00006159-00006166": "STEVEN ARGYLE WANTED IT. >> AJ: THEY'LL NEED ANOTHER", "caQeszpDOc0-00070-00006166-00006276": "STEVEN ARGYLE WANTED IT. >> AJ: THEY'LL NEED ANOTHER GREAT PERFORMANCE THURSDAY AS", "caQeszpDOc0-00071-00006276-00006282": ">> AJ: THEY'LL NEED ANOTHER GREAT PERFORMANCE THURSDAY AS", "caQeszpDOc0-00072-00006282-00006469": ">> AJ: THEY'LL NEED ANOTHER GREAT PERFORMANCE THURSDAY AS THE TEAM HAS DRAWN THE TOP SEED", "caQeszpDOc0-00073-00006469-00006476": "GREAT PERFORMANCE THURSDAY AS THE TEAM HAS DRAWN THE TOP SEED", "caQeszpDOc0-00074-00006476-00006599": "GREAT PERFORMANCE THURSDAY AS THE TEAM HAS DRAWN THE TOP SEED IN THE FIRST ROUND, BUT THEIR", "caQeszpDOc0-00075-00006599-00006606": "THE TEAM HAS DRAWN THE TOP SEED IN THE FIRST ROUND, BUT THEIR", "caQeszpDOc0-00076-00006606-00006820": "THE TEAM HAS DRAWN THE TOP SEED IN THE FIRST ROUND, BUT THEIR COACH IS CONFIDENT THEY CAN RISE", "caQeszpDOc0-00077-00006820-00006826": "IN THE FIRST ROUND, BUT THEIR COACH IS CONFIDENT THEY CAN RISE", "caQeszpDOc0-00078-00006826-00006963": "IN THE FIRST ROUND, BUT THEIR COACH IS CONFIDENT THEY CAN RISE TO THE OCCASION.", "caQeszpDOc0-00079-00006963-00006970": "COACH IS CONFIDENT THEY CAN RISE TO THE OCCASION.", "caQeszpDOc0-00080-00006970-00007147": "COACH IS CONFIDENT THEY CAN RISE TO THE OCCASION. >> PUT TWO GOOD HALVES OF", "caQeszpDOc0-00081-00007147-00007153": "TO THE OCCASION. >> PUT TWO GOOD HALVES OF", "caQeszpDOc0-00082-00007153-00007287": "TO THE OCCASION. >> PUT TWO GOOD HALVES OF BASKETBALL TEAM AND PLAY BOTH", "caQeszpDOc0-00083-00007287-00007293": ">> PUT TWO GOOD HALVES OF BASKETBALL TEAM AND PLAY BOTH", "caQeszpDOc0-00084-00007293-00007537": ">> PUT TWO GOOD HALVES OF BASKETBALL TEAM AND PLAY BOTH ENDS OF THE FLOOR, THEY CAN", "caQeszpDOc0-00085-00007537-00007544": "BASKETBALL TEAM AND PLAY BOTH ENDS OF THE FLOOR, THEY CAN", "caQeszpDOc0-00086-00007544-00007644": "BASKETBALL TEAM AND PLAY BOTH ENDS OF THE FLOOR, THEY CAN ACCOMPLISH ANYTHING.", "caQeszpDOc0-00087-00007644-00007650": "ENDS OF THE FLOOR, THEY CAN ACCOMPLISH ANYTHING.", "caQeszpDOc0-00088-00007650-00007747": "ENDS OF THE FLOOR, THEY CAN ACCOMPLISH ANYTHING. >> IN ADDITION TO PLAYING FOR", "caQeszpDOc0-00089-00007747-00007754": "ACCOMPLISH ANYTHING. >> IN ADDITION TO PLAYING FOR", "caQeszpDOc0-00090-00007754-00007891": "ACCOMPLISH ANYTHING. >> IN ADDITION TO PLAYING FOR THEMSELVES, THE WARRIORS WILL BE", "caQeszpDOc0-00091-00007891-00007897": ">> IN ADDITION TO PLAYING FOR THEMSELVES, THE WARRIORS WILL BE", "caQeszpDOc0-00092-00007897-00008158": ">> IN ADDITION TO PLAYING FOR THEMSELVES, THE WARRIORS WILL BE PLAYING THE COMMUNITY OF RELAKED", "caQeszpDOc0-00093-00008158-00008164": "THEMSELVES, THE WARRIORS WILL BE PLAYING THE COMMUNITY OF RELAKED", "caQeszpDOc0-00094-00008164-00008314": "THEMSELVES, THE WARRIORS WILL BE PLAYING THE COMMUNITY OF RELAKED LAKE WHO HAVE SUPPORTED THEM", "caQeszpDOc0-00095-00008314-00008321": "PLAYING THE COMMUNITY OF RELAKED LAKE WHO HAVE SUPPORTED THEM", "caQeszpDOc0-00096-00008321-00008438": "PLAYING THE COMMUNITY OF RELAKED LAKE WHO HAVE SUPPORTED THEM EVERY STEP OF THE WAY.", "caQeszpDOc0-00097-00008438-00008445": "LAKE WHO HAVE SUPPORTED THEM EVERY STEP OF THE WAY.", "caQeszpDOc0-00098-00008445-00008655": "LAKE WHO HAVE SUPPORTED THEM EVERY STEP OF THE WAY. >> WE TAKE SPORTS VERY SERIOUSLY", "caQeszpDOc0-00099-00008655-00008661": "EVERY STEP OF THE WAY. >> WE TAKE SPORTS VERY SERIOUSLY", "caQeszpDOc0-00100-00008661-00008792": "EVERY STEP OF THE WAY. >> WE TAKE SPORTS VERY SERIOUSLY AROUND HERE.", "caQeszpDOc0-00101-00008792-00008798": ">> WE TAKE SPORTS VERY SERIOUSLY AROUND HERE.", "caQeszpDOc0-00102-00008798-00009239": ">> WE TAKE SPORTS VERY SERIOUSLY AROUND HERE. SOMETIMES THAT'S THE ONLY THING", "caQeszpDOc0-00103-00009239-00009245": "AROUND HERE. SOMETIMES THAT'S THE ONLY THING", "caQeszpDOc0-00104-00009245-00009482": "AROUND HERE. SOMETIMES THAT'S THE ONLY THING THEY HAVE TO LOOK FORWARD TO.", "caQeszpDOc0-00105-00009482-00009489": "SOMETIMES THAT'S THE ONLY THING THEY HAVE TO LOOK FORWARD TO.", "caQeszpDOc0-00106-00009489-00009652": "SOMETIMES THAT'S THE ONLY THING THEY HAVE TO LOOK FORWARD TO. >> FRIENDS PUSH US MORE.", "caQeszpDOc0-00107-00009652-00009659": "THEY HAVE TO LOOK FORWARD TO. >> FRIENDS PUSH US MORE.", "caQeszpDOc0-00108-00009659-00009919": "THEY HAVE TO LOOK FORWARD TO. >> FRIENDS PUSH US MORE. EVERYTHING WE DO FOR THEM.", "caQeszpDOc0-00109-00009919-00009926": ">> FRIENDS PUSH US MORE. EVERYTHING WE DO FOR THEM.", "caQeszpDOc0-00110-00009926-00010120": ">> FRIENDS PUSH US MORE. EVERYTHING WE DO FOR THEM. EVERYBODY IS GOING TO FOLLOW.", "caQeszpDOc0-00111-00010120-00010126": "EVERYTHING WE DO FOR THEM. EVERYBODY IS GOING TO FOLLOW.", "caQeszpDOc0-00112-00010126-00010230": "EVERYTHING WE DO FOR THEM. EVERYBODY IS GOING TO FOLLOW. >> AJ: YOU CAN EXPECT A BIG", "caQeszpDOc0-00113-00010230-00010236": "EVERYBODY IS GOING TO FOLLOW. >> AJ: YOU CAN EXPECT A BIG", "caQeszpDOc0-00114-00010236-00010580": "EVERYBODY IS GOING TO FOLLOW. >> AJ: YOU CAN EXPECT A BIG CROWD THURSDAY AT U OF M FOR", "caQeszpDOc0-00115-00010580-00010587": ">> AJ: YOU CAN EXPECT A BIG CROWD THURSDAY AT U OF M FOR", "caQeszpDOc0-00116-00010587-00010633": ">> AJ: YOU CAN EXPECT A BIG CROWD THURSDAY AT U OF M FOR THEIR FIRST ROUND MATCH-UP."}}, {"audio_id": "caVwb4xFR8u", "text": {"caVwb4xFR8u-00000-00000272-00000903": "Getting this complete set first was really important to me because I felt like we had", "caVwb4xFR8u-00001-00000903-00001552": "this set of portraits and it didn't include our two women presidents. And I felt like we", "caVwb4xFR8u-00002-00001552-00001936": "needed to show that we were interested in preserving the history of the university.", "caVwb4xFR8u-00003-00002056-00002576": "That's why I thought it was especially important to work with the President's Office and the Center", "caVwb4xFR8u-00004-00002576-00003215": "for Advancement to commission the new portraits to complete the set and commit to getting portraits", "caVwb4xFR8u-00005-00003215-00003904": "of all future presidents down the road. So the Presidential Portrait Gallery really falls under", "caVwb4xFR8u-00006-00003904-00004560": "my purview because I'm responsible as a university conservator for all the care of the collections", "caVwb4xFR8u-00007-00004560-00005144": "and this includes paintings so as a book conservator I have to spread my wings a little bit", "caVwb4xFR8u-00008-00005144-00005784": "and look at other kinds of materials and of course the paintings fall into that category", "caVwb4xFR8u-00009-00005904-00006232": "the painting conservator that we selected was Sara Boesen.", "caVwb4xFR8u-00010-00006288-00007016": "Sara is a native Iowan and she did really amazing training outside of Iowa. She studied in Europe", "caVwb4xFR8u-00011-00007016-00007584": "but also in Chicago, and this kind of experience is really imperative to find a really skilled", "caVwb4xFR8u-00012-00007584-00008120": "paintings conservator. We wanted the best that we could find for our collection of paintings.", "caVwb4xFR8u-00013-00008216-00008872": "The University of Iowa reached out to me regarding several portraits of former presidents", "caVwb4xFR8u-00014-00008872-00009592": "of the university that are in need of some conservation work. I went and examined them and", "caVwb4xFR8u-00015-00009768-00010352": "there's a wide variety of need throughout them the Spencer portrait is definitely in the most need", "caVwb4xFR8u-00016-00010472-00011200": "I wanted to show you kind of the under layers of the painting so I've removed a synthetic varnish", "caVwb4xFR8u-00017-00011200-00011856": "that's on part of the painting and then I've also removed some of the natural resin original", "caVwb4xFR8u-00018-00011856-00012464": "varnish as well so you can see the differences between the two. You can see some of the damage", "caVwb4xFR8u-00019-00012464-00013128": "of the painting and you can also see what it the part that I have not cleaned you can see", "caVwb4xFR8u-00020-00013216-00013872": "where it's kind of coming from and why it needs to be addressed. So I'll try to continue some", "caVwb4xFR8u-00021-00013872-00014696": "of that shaping like around the ear with this darker bit of hair and I'll bring in", "caVwb4xFR8u-00022-00014800-00015608": "this dark red for the side of the face. Portraits really draw the viewer in", "caVwb4xFR8u-00023-00015712-00016344": "a way that we relate to the sitter relate to the person in the portrait and I feel that", "caVwb4xFR8u-00024-00016344-00016872": "people can start to relate a little bit with the university history as they see each president,", "caVwb4xFR8u-00025-00016872-00017624": "as they see the unique character characteristics of each president as they look at the portraits.", "caVwb4xFR8u-00026-00017624-00018448": "I think that's really important for us to to preserve. Without art conservation artworks", "caVwb4xFR8u-00027-00018512-00019144": "will die eventually. You won't be able to see them anymore. Damages can't be fixed and", "caVwb4xFR8u-00028-00019208-00019728": "you lose history. The Presidential Portrait Gallery isn't just portraits on the wall. It's", "caVwb4xFR8u-00029-00019728-00020328": "not just works of art in oil or drawings what have you. It really is living history and it's", "caVwb4xFR8u-00030-00020328-00020784": "a way for us to track that history and make it available to students faculty and the community.", "caVwb4xFR8u-00031-00020840-00021336": "And I think this is part of the Libraries responsibility to the university to help", "caVwb4xFR8u-00032-00021336-00022008": "preserve these portraits and to create a space where folks can come to learn more and to have", "caVwb4xFR8u-00033-00022008-00022584": "conversations about the role of leadership in the university in the world and beyond."}}, {"audio_id": "cac0HpeaLUy", "text": {"cac0HpeaLUy-00000-00005888-00006096": "And as always,", "cac0HpeaLUy-00001-00006096-00006318": "Subscribe to PewDiePie"}}, {"audio_id": "cb0dctYFIFg", "text": {"cb0dctYFIFg-00000-00000010-00000387": "WEBSITE AT LPTV.ORG/NEWS.", "cb0dctYFIFg-00001-00000387-00000393": "WEBSITE AT LPTV.ORG/NEWS.", "cb0dctYFIFg-00002-00000393-00000597": "WEBSITE AT LPTV.ORG/NEWS. >>> WE HAVE ALL HEARD THE SAYING", "cb0dctYFIFg-00003-00000597-00000603": "WEBSITE AT LPTV.ORG/NEWS. >>> WE HAVE ALL HEARD THE SAYING", "cb0dctYFIFg-00004-00000603-00000810": "WEBSITE AT LPTV.ORG/NEWS. >>> WE HAVE ALL HEARD THE SAYING NEW YEAR NEW BODY BUT IT COULD", "cb0dctYFIFg-00005-00000810-00000817": ">>> WE HAVE ALL HEARD THE SAYING NEW YEAR NEW BODY BUT IT COULD", "cb0dctYFIFg-00006-00000817-00001014": ">>> WE HAVE ALL HEARD THE SAYING NEW YEAR NEW BODY BUT IT COULD BE CHALLENGING TO STICK WITH", "cb0dctYFIFg-00007-00001014-00001021": "NEW YEAR NEW BODY BUT IT COULD BE CHALLENGING TO STICK WITH", "cb0dctYFIFg-00008-00001021-00001221": "NEW YEAR NEW BODY BUT IT COULD BE CHALLENGING TO STICK WITH THAT RESOLUTION.", "cb0dctYFIFg-00009-00001221-00001227": "BE CHALLENGING TO STICK WITH THAT RESOLUTION.", "cb0dctYFIFg-00010-00001227-00001461": "BE CHALLENGING TO STICK WITH THAT RESOLUTION. HAYDEE CLOTTER HAS A STORY HOW", "cb0dctYFIFg-00011-00001461-00001468": "THAT RESOLUTION. HAYDEE CLOTTER HAS A STORY HOW", "cb0dctYFIFg-00012-00001468-00001811": "THAT RESOLUTION. HAYDEE CLOTTER HAS A STORY HOW TO TURN IT INTO A NEW LIFE.", "cb0dctYFIFg-00013-00001811-00001818": "HAYDEE CLOTTER HAS A STORY HOW TO TURN IT INTO A NEW LIFE.", "cb0dctYFIFg-00014-00001818-00002031": "HAYDEE CLOTTER HAS A STORY HOW TO TURN IT INTO A NEW LIFE. >> THE START OF THE NEW YEAR", "cb0dctYFIFg-00015-00002031-00002038": "TO TURN IT INTO A NEW LIFE. >> THE START OF THE NEW YEAR", "cb0dctYFIFg-00016-00002038-00002245": "TO TURN IT INTO A NEW LIFE. >> THE START OF THE NEW YEAR BRINGS WEIGHT LOSS GOALS FOR", "cb0dctYFIFg-00017-00002245-00002252": ">> THE START OF THE NEW YEAR BRINGS WEIGHT LOSS GOALS FOR", "cb0dctYFIFg-00018-00002252-00002495": ">> THE START OF THE NEW YEAR BRINGS WEIGHT LOSS GOALS FOR MANY, AND MEAP WERE ACTIVE AND", "cb0dctYFIFg-00019-00002495-00002502": "BRINGS WEIGHT LOSS GOALS FOR MANY, AND MEAP WERE ACTIVE AND", "cb0dctYFIFg-00020-00002502-00002589": "BRINGS WEIGHT LOSS GOALS FOR MANY, AND MEAP WERE ACTIVE AND SWEATING IT OUT.", "cb0dctYFIFg-00021-00002589-00002595": "MANY, AND MEAP WERE ACTIVE AND SWEATING IT OUT.", "cb0dctYFIFg-00022-00002595-00002719": "MANY, AND MEAP WERE ACTIVE AND SWEATING IT OUT. >> A LOT OF PEOPLE GET", "cb0dctYFIFg-00023-00002719-00002726": "SWEATING IT OUT. >> A LOT OF PEOPLE GET", "cb0dctYFIFg-00024-00002726-00002889": "SWEATING IT OUT. >> A LOT OF PEOPLE GET FRUSTRATED WHEN THEY COME IN AND", "cb0dctYFIFg-00025-00002889-00002896": ">> A LOT OF PEOPLE GET FRUSTRATED WHEN THEY COME IN AND", "cb0dctYFIFg-00026-00002896-00002992": ">> A LOT OF PEOPLE GET FRUSTRATED WHEN THEY COME IN AND DON'T SEE RESULTS.", "cb0dctYFIFg-00027-00002992-00002999": "FRUSTRATED WHEN THEY COME IN AND DON'T SEE RESULTS.", "cb0dctYFIFg-00028-00002999-00003183": "FRUSTRATED WHEN THEY COME IN AND DON'T SEE RESULTS. IT'S NOT ALWAYS ABOUT THE NUMBER", "cb0dctYFIFg-00029-00003183-00003189": "DON'T SEE RESULTS. IT'S NOT ALWAYS ABOUT THE NUMBER", "cb0dctYFIFg-00030-00003189-00003349": "DON'T SEE RESULTS. IT'S NOT ALWAYS ABOUT THE NUMBER ON THE SCALE OR HOW YOU ARE", "cb0dctYFIFg-00031-00003349-00003356": "IT'S NOT ALWAYS ABOUT THE NUMBER ON THE SCALE OR HOW YOU ARE", "cb0dctYFIFg-00032-00003356-00003530": "IT'S NOT ALWAYS ABOUT THE NUMBER ON THE SCALE OR HOW YOU ARE LOOKING, BUT MORE IMPORTANTLY", "cb0dctYFIFg-00033-00003530-00003536": "ON THE SCALE OR HOW YOU ARE LOOKING, BUT MORE IMPORTANTLY", "cb0dctYFIFg-00034-00003536-00003650": "ON THE SCALE OR HOW YOU ARE LOOKING, BUT MORE IMPORTANTLY HOW YOU ARE FEELING.", "cb0dctYFIFg-00035-00003650-00003656": "LOOKING, BUT MORE IMPORTANTLY HOW YOU ARE FEELING.", "cb0dctYFIFg-00036-00003656-00003913": "LOOKING, BUT MORE IMPORTANTLY HOW YOU ARE FEELING. >> THERE'S ALSO A TREND.", "cb0dctYFIFg-00037-00003913-00003920": "HOW YOU ARE FEELING. >> THERE'S ALSO A TREND.", "cb0dctYFIFg-00038-00003920-00004084": "HOW YOU ARE FEELING. >> THERE'S ALSO A TREND. AFTER THE FIRST FEW DAYS INTO", "cb0dctYFIFg-00039-00004084-00004090": ">> THERE'S ALSO A TREND. AFTER THE FIRST FEW DAYS INTO", "cb0dctYFIFg-00040-00004090-00004384": ">> THERE'S ALSO A TREND. AFTER THE FIRST FEW DAYS INTO THE YEAR, THE GYM TRAFFIC FADES", "cb0dctYFIFg-00041-00004384-00004391": "AFTER THE FIRST FEW DAYS INTO THE YEAR, THE GYM TRAFFIC FADES", "cb0dctYFIFg-00042-00004391-00004411": "AFTER THE FIRST FEW DAYS INTO THE YEAR, THE GYM TRAFFIC FADES OUT.", "cb0dctYFIFg-00043-00004411-00004417": "THE YEAR, THE GYM TRAFFIC FADES OUT.", "cb0dctYFIFg-00044-00004417-00004644": "THE YEAR, THE GYM TRAFFIC FADES OUT. >> FOR THE FIRST COUPLE WEEKS, A", "cb0dctYFIFg-00045-00004644-00004651": "OUT. >> FOR THE FIRST COUPLE WEEKS, A", "cb0dctYFIFg-00046-00004651-00004908": "OUT. >> FOR THE FIRST COUPLE WEEKS, A LOT OF PEOPLE SIGN UP, AND WHEN", "cb0dctYFIFg-00047-00004908-00004914": ">> FOR THE FIRST COUPLE WEEKS, A LOT OF PEOPLE SIGN UP, AND WHEN", "cb0dctYFIFg-00048-00004914-00005291": ">> FOR THE FIRST COUPLE WEEKS, A LOT OF PEOPLE SIGN UP, AND WHEN IT GETS NICER IS WHEN WE SEE FEW", "cb0dctYFIFg-00049-00005291-00005298": "LOT OF PEOPLE SIGN UP, AND WHEN IT GETS NICER IS WHEN WE SEE FEW", "cb0dctYFIFg-00050-00005298-00005548": "LOT OF PEOPLE SIGN UP, AND WHEN IT GETS NICER IS WHEN WE SEE FEW STICKING WITH IT.", "cb0dctYFIFg-00051-00005548-00005555": "IT GETS NICER IS WHEN WE SEE FEW STICKING WITH IT.", "cb0dctYFIFg-00052-00005555-00005675": "IT GETS NICER IS WHEN WE SEE FEW STICKING WITH IT. >> WORKING OUT ON THE TREADMILL", "cb0dctYFIFg-00053-00005675-00005682": "STICKING WITH IT. >> WORKING OUT ON THE TREADMILL", "cb0dctYFIFg-00054-00005682-00006039": "STICKING WITH IT. >> WORKING OUT ON THE TREADMILL IS A QUICK AND EFFECTIVE WAY TO", "cb0dctYFIFg-00055-00006039-00006046": ">> WORKING OUT ON THE TREADMILL IS A QUICK AND EFFECTIVE WAY TO", "cb0dctYFIFg-00056-00006046-00006076": ">> WORKING OUT ON THE TREADMILL IS A QUICK AND EFFECTIVE WAY TO EXERCISE.", "cb0dctYFIFg-00057-00006076-00006082": "IS A QUICK AND EFFECTIVE WAY TO EXERCISE.", "cb0dctYFIFg-00058-00006082-00006366": "IS A QUICK AND EFFECTIVE WAY TO EXERCISE. YOU CAN BURN HUNDREDS OF", "cb0dctYFIFg-00059-00006366-00006373": "EXERCISE. YOU CAN BURN HUNDREDS OF", "cb0dctYFIFg-00060-00006373-00006633": "EXERCISE. YOU CAN BURN HUNDREDS OF CALORIES.", "cb0dctYFIFg-00061-00006633-00006639": "YOU CAN BURN HUNDREDS OF CALORIES.", "cb0dctYFIFg-00062-00006639-00006766": "YOU CAN BURN HUNDREDS OF CALORIES. >> EACH PERSON IS DIFFERENT, SO", "cb0dctYFIFg-00063-00006766-00006773": "CALORIES. >> EACH PERSON IS DIFFERENT, SO", "cb0dctYFIFg-00064-00006773-00007056": "CALORIES. >> EACH PERSON IS DIFFERENT, SO NOT EVERYONE WILL HAVE THE SAME", "cb0dctYFIFg-00065-00007056-00007063": ">> EACH PERSON IS DIFFERENT, SO NOT EVERYONE WILL HAVE THE SAME", "cb0dctYFIFg-00066-00007063-00007113": ">> EACH PERSON IS DIFFERENT, SO NOT EVERYONE WILL HAVE THE SAME GOALS.", "cb0dctYFIFg-00067-00007113-00007120": "NOT EVERYONE WILL HAVE THE SAME GOALS.", "cb0dctYFIFg-00068-00007120-00007237": "NOT EVERYONE WILL HAVE THE SAME GOALS. >> SOME MIGHT BE WEIGHT LOSS,", "cb0dctYFIFg-00069-00007237-00007243": "GOALS. >> SOME MIGHT BE WEIGHT LOSS,", "cb0dctYFIFg-00070-00007243-00007330": "GOALS. >> SOME MIGHT BE WEIGHT LOSS, BUILDING MUSCLE.", "cb0dctYFIFg-00071-00007330-00007337": ">> SOME MIGHT BE WEIGHT LOSS, BUILDING MUSCLE.", "cb0dctYFIFg-00072-00007337-00007540": ">> SOME MIGHT BE WEIGHT LOSS, BUILDING MUSCLE. IT'S NOT JUST A GENERIC WORK", "cb0dctYFIFg-00073-00007540-00007547": "BUILDING MUSCLE. IT'S NOT JUST A GENERIC WORK", "cb0dctYFIFg-00074-00007547-00007567": "BUILDING MUSCLE. IT'S NOT JUST A GENERIC WORK OUT.", "cb0dctYFIFg-00075-00007567-00007574": "IT'S NOT JUST A GENERIC WORK OUT.", "cb0dctYFIFg-00076-00007574-00007877": "IT'S NOT JUST A GENERIC WORK OUT. I MEAN, THERE IS, BUT WE TAYLOR", "cb0dctYFIFg-00077-00007877-00007884": "OUT. I MEAN, THERE IS, BUT WE TAYLOR", "cb0dctYFIFg-00078-00007884-00008024": "OUT. I MEAN, THERE IS, BUT WE TAYLOR WORK OUTS SPECIFIC TO PEOPLE'S", "cb0dctYFIFg-00079-00008024-00008031": "I MEAN, THERE IS, BUT WE TAYLOR WORK OUTS SPECIFIC TO PEOPLE'S", "cb0dctYFIFg-00080-00008031-00008174": "I MEAN, THERE IS, BUT WE TAYLOR WORK OUTS SPECIFIC TO PEOPLE'S GOALS AND NEEDS AND STUFF LIKE", "cb0dctYFIFg-00081-00008174-00008181": "WORK OUTS SPECIFIC TO PEOPLE'S GOALS AND NEEDS AND STUFF LIKE", "cb0dctYFIFg-00082-00008181-00008214": "WORK OUTS SPECIFIC TO PEOPLE'S GOALS AND NEEDS AND STUFF LIKE THAT.", "cb0dctYFIFg-00083-00008214-00008221": "GOALS AND NEEDS AND STUFF LIKE THAT.", "cb0dctYFIFg-00084-00008221-00008348": "GOALS AND NEEDS AND STUFF LIKE THAT. >> AS A PERSONAL TRAINER THE", "cb0dctYFIFg-00085-00008348-00008355": "THAT. >> AS A PERSONAL TRAINER THE", "cb0dctYFIFg-00086-00008355-00008565": "THAT. >> AS A PERSONAL TRAINER THE MAIN JOB IS TO MOTIVATE A CLIENT", "cb0dctYFIFg-00087-00008565-00008571": ">> AS A PERSONAL TRAINER THE MAIN JOB IS TO MOTIVATE A CLIENT", "cb0dctYFIFg-00088-00008571-00008815": ">> AS A PERSONAL TRAINER THE MAIN JOB IS TO MOTIVATE A CLIENT AND HELP THEM REACH THEIR GOALS,", "cb0dctYFIFg-00089-00008815-00008822": "MAIN JOB IS TO MOTIVATE A CLIENT AND HELP THEM REACH THEIR GOALS,", "cb0dctYFIFg-00090-00008822-00009242": "MAIN JOB IS TO MOTIVATE A CLIENT AND HELP THEM REACH THEIR GOALS, WHATEVER THEY MAY BE.", "cb0dctYFIFg-00091-00009242-00009249": "AND HELP THEM REACH THEIR GOALS, WHATEVER THEY MAY BE.", "cb0dctYFIFg-00092-00009249-00009436": "AND HELP THEM REACH THEIR GOALS, WHATEVER THEY MAY BE. >> EVERY YEAR AFTER JANUARY, ALL", "cb0dctYFIFg-00093-00009436-00009442": "WHATEVER THEY MAY BE. >> EVERY YEAR AFTER JANUARY, ALL", "cb0dctYFIFg-00094-00009442-00009579": "WHATEVER THEY MAY BE. >> EVERY YEAR AFTER JANUARY, ALL THE NEW YEAR'S RESOLUTIONS,", "cb0dctYFIFg-00095-00009579-00009586": ">> EVERY YEAR AFTER JANUARY, ALL THE NEW YEAR'S RESOLUTIONS,", "cb0dctYFIFg-00096-00009586-00010113": ">> EVERY YEAR AFTER JANUARY, ALL THE NEW YEAR'S RESOLUTIONS, PEOPLE FALL FROM THAT AND HAVING", "cb0dctYFIFg-00097-00010113-00010120": "THE NEW YEAR'S RESOLUTIONS, PEOPLE FALL FROM THAT AND HAVING", "cb0dctYFIFg-00098-00010120-00010306": "THE NEW YEAR'S RESOLUTIONS, PEOPLE FALL FROM THAT AND HAVING THAT ACCOUNTABILITY AS A", "cb0dctYFIFg-00099-00010306-00010313": "PEOPLE FALL FROM THAT AND HAVING THAT ACCOUNTABILITY AS A", "cb0dctYFIFg-00100-00010313-00010560": "PEOPLE FALL FROM THAT AND HAVING THAT ACCOUNTABILITY AS A TRAWNER, VOTE VAIT THEM.", "cb0dctYFIFg-00101-00010560-00010567": "THAT ACCOUNTABILITY AS A TRAWNER, VOTE VAIT THEM.", "cb0dctYFIFg-00102-00010567-00010787": "THAT ACCOUNTABILITY AS A TRAWNER, VOTE VAIT THEM. >> AND HE'S USING THE NEW YEAR", "cb0dctYFIFg-00103-00010787-00010794": "TRAWNER, VOTE VAIT THEM. >> AND HE'S USING THE NEW YEAR", "cb0dctYFIFg-00104-00010794-00010924": "TRAWNER, VOTE VAIT THEM. >> AND HE'S USING THE NEW YEAR THAT BEGAN LAST YEAR, AND IT", "cb0dctYFIFg-00105-00010924-00010930": ">> AND HE'S USING THE NEW YEAR THAT BEGAN LAST YEAR, AND IT", "cb0dctYFIFg-00106-00010930-00011124": ">> AND HE'S USING THE NEW YEAR THAT BEGAN LAST YEAR, AND IT TOOK A WAKE-UP CALL FOR HIM TO", "cb0dctYFIFg-00107-00011124-00011131": "THAT BEGAN LAST YEAR, AND IT TOOK A WAKE-UP CALL FOR HIM TO", "cb0dctYFIFg-00108-00011131-00011207": "THAT BEGAN LAST YEAR, AND IT TOOK A WAKE-UP CALL FOR HIM TO CHANGE HIS LIFE.", "cb0dctYFIFg-00109-00011207-00011214": "TOOK A WAKE-UP CALL FOR HIM TO CHANGE HIS LIFE.", "cb0dctYFIFg-00110-00011214-00011574": "TOOK A WAKE-UP CALL FOR HIM TO CHANGE HIS LIFE. >> I GOT MY SECOND DWI A YEAR", "cb0dctYFIFg-00111-00011574-00011581": "CHANGE HIS LIFE. >> I GOT MY SECOND DWI A YEAR", "cb0dctYFIFg-00112-00011581-00011785": "CHANGE HIS LIFE. >> I GOT MY SECOND DWI A YEAR AND A HALF AGO.", "cb0dctYFIFg-00113-00011785-00011791": ">> I GOT MY SECOND DWI A YEAR AND A HALF AGO.", "cb0dctYFIFg-00114-00011791-00012025": ">> I GOT MY SECOND DWI A YEAR AND A HALF AGO. HAVEN'T DRANK SENSE 540 DAYS.", "cb0dctYFIFg-00115-00012025-00012032": "AND A HALF AGO. HAVEN'T DRANK SENSE 540 DAYS.", "cb0dctYFIFg-00116-00012032-00012358": "AND A HALF AGO. HAVEN'T DRANK SENSE 540 DAYS. I DECIDED TO MAKE A CHANGE IN MY", "cb0dctYFIFg-00117-00012358-00012365": "HAVEN'T DRANK SENSE 540 DAYS. I DECIDED TO MAKE A CHANGE IN MY", "cb0dctYFIFg-00118-00012365-00012395": "HAVEN'T DRANK SENSE 540 DAYS. I DECIDED TO MAKE A CHANGE IN MY LIFESTYLE.", "cb0dctYFIFg-00119-00012395-00012402": "I DECIDED TO MAKE A CHANGE IN MY LIFESTYLE.", "cb0dctYFIFg-00120-00012402-00012555": "I DECIDED TO MAKE A CHANGE IN MY LIFESTYLE. >> AND LOST NEARLY 40 POUNDS IN", "cb0dctYFIFg-00121-00012555-00012562": "LIFESTYLE. >> AND LOST NEARLY 40 POUNDS IN", "cb0dctYFIFg-00122-00012562-00012819": "LIFESTYLE. >> AND LOST NEARLY 40 POUNDS IN THE PROCESS, AND SURPASSED THE", "cb0dctYFIFg-00123-00012819-00012826": ">> AND LOST NEARLY 40 POUNDS IN THE PROCESS, AND SURPASSED THE", "cb0dctYFIFg-00124-00012826-00012936": ">> AND LOST NEARLY 40 POUNDS IN THE PROCESS, AND SURPASSED THE WEIGHT LOSS TARGET AND CONTINUES", "cb0dctYFIFg-00125-00012936-00012942": "THE PROCESS, AND SURPASSED THE WEIGHT LOSS TARGET AND CONTINUES", "cb0dctYFIFg-00126-00012942-00013089": "THE PROCESS, AND SURPASSED THE WEIGHT LOSS TARGET AND CONTINUES TO LOSE MORE WEIGHT.", "cb0dctYFIFg-00127-00013089-00013096": "WEIGHT LOSS TARGET AND CONTINUES TO LOSE MORE WEIGHT.", "cb0dctYFIFg-00128-00013096-00013339": "WEIGHT LOSS TARGET AND CONTINUES TO LOSE MORE WEIGHT. >> STARTED OFF AT 319 AND I'M", "cb0dctYFIFg-00129-00013339-00013346": "TO LOSE MORE WEIGHT. >> STARTED OFF AT 319 AND I'M", "cb0dctYFIFg-00130-00013346-00013606": "TO LOSE MORE WEIGHT. >> STARTED OFF AT 319 AND I'M 280 WITH MUSCLE AND STARTING A", "cb0dctYFIFg-00131-00013606-00013613": ">> STARTED OFF AT 319 AND I'M 280 WITH MUSCLE AND STARTING A", "cb0dctYFIFg-00132-00013613-00013757": ">> STARTED OFF AT 319 AND I'M 280 WITH MUSCLE AND STARTING A NEW PROGRAM CALLED SHRED, AND", "cb0dctYFIFg-00133-00013757-00013763": "280 WITH MUSCLE AND STARTING A NEW PROGRAM CALLED SHRED, AND", "cb0dctYFIFg-00134-00013763-00014043": "280 WITH MUSCLE AND STARTING A NEW PROGRAM CALLED SHRED, AND IT'S A SIX WEEK PROGRAM.", "cb0dctYFIFg-00135-00014043-00014050": "NEW PROGRAM CALLED SHRED, AND IT'S A SIX WEEK PROGRAM.", "cb0dctYFIFg-00136-00014050-00014284": "NEW PROGRAM CALLED SHRED, AND IT'S A SIX WEEK PROGRAM. >> ON YOUR MARK, GET SET, GO", "cb0dctYFIFg-00137-00014284-00014290": "IT'S A SIX WEEK PROGRAM. >> ON YOUR MARK, GET SET, GO", "cb0dctYFIFg-00138-00014290-00014614": "IT'S A SIX WEEK PROGRAM. >> ON YOUR MARK, GET SET, GO TRAIN, IN BEMIDJI, HAYDEE", "cb0dctYFIFg-00139-00014614-00014621": ">> ON YOUR MARK, GET SET, GO TRAIN, IN BEMIDJI, HAYDEE", "cb0dctYFIFg-00140-00014621-00014744": ">> ON YOUR MARK, GET SET, GO TRAIN, IN BEMIDJI, HAYDEE CLOTTER, LAKELAND NEWS.", "cb0dctYFIFg-00141-00014744-00014751": "TRAIN, IN BEMIDJI, HAYDEE CLOTTER, LAKELAND NEWS.", "cb0dctYFIFg-00142-00014751-00014828": "TRAIN, IN BEMIDJI, HAYDEE CLOTTER, LAKELAND NEWS. >> REMEMBER, ANY GOAL YOU SET IS"}}, {"audio_id": "cb7QXT_VUHE", "text": {"cb7QXT_VUHE-00000-00000152-00000632": "hi this is renae olivia and in this video i'm going to be doing a mini Vici haul but", "cb7QXT_VUHE-00001-00000632-00001040": "i've got some really great pieces that i'm going to style several different ways for", "cb7QXT_VUHE-00002-00001040-00001552": "you so i'm super excited i know you're going to love these pieces so stick around but first", "cb7QXT_VUHE-00003-00001552-00002039": "if you're not already a subscriber please hit that bell and the subscribe button that way you never", "cb7QXT_VUHE-00004-00002039-00002608": "miss any of my videos every week it would mean the world to me and just in case you're not aware", "cb7QXT_VUHE-00005-00002608-00003264": "of what my channel is about it's really about women over 30 over 40 even over 50 and beyond", "cb7QXT_VUHE-00006-00003264-00003960": "feeling their best looking their best and really coming to terms with aging in a graceful", "cb7QXT_VUHE-00007-00003960-00004576": "and respectful way i have been on social media for three years now and i get a lot of", "cb7QXT_VUHE-00008-00004648-00005392": "what's this grandma doing on TikTok or instagram and all this really derogatory", "cb7QXT_VUHE-00009-00005480-00006368": "um statements and insults around aging and it's shaming someone for their age and that's really", "cb7QXT_VUHE-00010-00006368-00007048": "upsetting to me because we i'm 50 when we're when we get to middle age we don't want to be invisible", "cb7QXT_VUHE-00011-00007112-00007816": "i just i'm trying to age in a graceful way and i'm just giving you tips and tip uh tricks on", "cb7QXT_VUHE-00012-00007816-00008672": "how i go about it you don't it's not like um this is the end all be all it really is about feeling", "cb7QXT_VUHE-00013-00008672-00009168": "your best and that's what i'm trying to convey and i hope that you get that feeling from my", "cb7QXT_VUHE-00014-00009168-00009784": "channel but anyway i know i went on a tangent but i've been getting a lot of insults lately and um", "cb7QXT_VUHE-00015-00009840-00010424": "i don't know why there's so much anger about growing old because these 20 year olds that are", "cb7QXT_VUHE-00016-00010424-00010904": "saying this to me what do they think they think they're not going to be 50 year old", "cb7QXT_VUHE-00017-00010904-00011488": "50 year old someday like if you're not going to be 50 that means the alternative is not so great", "cb7QXT_VUHE-00018-00011488-00012160": "so i don't understand the shaming let's stop the hate and just be kind to people so that's all i", "cb7QXT_VUHE-00019-00012160-00012704": "wanted to say let's get to the video i'm sorry on that i put on that tangent let's get to the video", "cb7QXT_VUHE-00020-00012704-00013384": "okay so this is the first um item that i want to show you from Vici that i really really love", "cb7QXT_VUHE-00021-00013384-00014208": "this is a chunky gray oversized sweater i just um this is it out and it's really cute it's got", "cb7QXT_VUHE-00022-00014208-00014904": "like the um different uh length hem which is great covers your booty if you want to cover your booty", "cb7QXT_VUHE-00023-00014960-00015608": "um and i like the little v right here um i'm so sorry like i feel like i'm getting a cold", "cb7QXT_VUHE-00024-00015608-00016472": "so i apologize for my voice right now um but i love this cozy knit it really does", "cb7QXT_VUHE-00025-00016472-00017264": "just make me happy so i'm i like to do the front tuck i just paired it with um some distressed", "cb7QXT_VUHE-00026-00017264-00018000": "denim and some booties which i think are really cute um so my point is you can dress this up", "cb7QXT_VUHE-00027-00018056-00018752": "or what you can do is i'm going to switch it up dress it down a little and then i also want", "cb7QXT_VUHE-00028-00018752-00019408": "to adjust it up for work as well so let me do the more casual so again this is like oh let's", "cb7QXT_VUHE-00029-00019408-00019944": "go out for drinks happy hour kind of winter outfit and i'm going to show you now like the", "cb7QXT_VUHE-00030-00020088-00020768": "going out to the soccer game or picking up your kids from school so this is like the more casual", "cb7QXT_VUHE-00031-00020768-00021440": "look i just paired it with like a cross body bag and some converse sneakers you can do like the", "cb7QXT_VUHE-00032-00021440-00022072": "chunky sneakers um again the jeans work well with this and again this is just like a great", "cb7QXT_VUHE-00033-00022128-00022776": "running to the grocery store getting your kids kind of easy casual outfit but you still look", "cb7QXT_VUHE-00034-00022776-00023400": "really put together and again i just i just love it just makes me happy this little cozy knit so", "cb7QXT_VUHE-00035-00023400-00024264": "let me also style this for work as well i love it okay hopefully you can see the whole look i really", "cb7QXT_VUHE-00036-00024264-00025112": "love it with these uh cream um trousers that i got from Reiss they're just super chic um super", "cb7QXT_VUHE-00037-00025112-00025760": "professional like i love this whole look and then i just added like a tote like a structured tote", "cb7QXT_VUHE-00038-00025760-00026552": "to really um complete the professional uh chic look of the um the outfit again this is such a", "cb7QXT_VUHE-00039-00026552-00027424": "versatile sweater it can go from casual to drinks to work on super easily and it's comfortable and", "cb7QXT_VUHE-00040-00027424-00028032": "it's affordable so you really can't go wrong i really really am impressed with this it comes", "cb7QXT_VUHE-00041-00028032-00028536": "in three different colors i'm wearing the small i believe the smallest the smallest they have", "cb7QXT_VUHE-00042-00028616-00029336": "but i'll double check and um they're always Vici's always having sales so i did get like a sale on it", "cb7QXT_VUHE-00043-00029336-00029968": "if there's a sale i'll put the code in i think i got mine was thank you 25 and i got 25 off so", "cb7QXT_VUHE-00044-00029968-00030656": "they always have great sales so i love it let's go to the next item okay so this is the next um", "cb7QXT_VUHE-00045-00030656-00031272": "item i got from Vici which i really love it's different i've actually been seeing these um", "cb7QXT_VUHE-00046-00031272-00032024": "the style of wrap sweater cardigan um lately everywhere and this one i don't know it just", "cb7QXT_VUHE-00047-00032024-00032383": "spoke to me i just feel like the black and white is super chic super elegant", "cb7QXT_VUHE-00048-00032448-00033160": "um and super fashionable i love the wrap like it's just it's super cozy and for this", "cb7QXT_VUHE-00049-00033160-00033728": "outfit i just paired it with some faux leather leggings and some slouchy suede boots again a", "cb7QXT_VUHE-00050-00033728-00034368": "great fall winter look um you can be going out to drinks going to date night going to the movies", "cb7QXT_VUHE-00051-00034368-00034976": "are people going to the movies now i don't know um sorry i haven't been in the movies in like", "cb7QXT_VUHE-00052-00034976-00035616": "two years so i'm not quite sure um so yeah so i love it i'm gonna style it a couple different ways", "cb7QXT_VUHE-00053-00035616-00036096": "for you so you can get like different um ways you can wear it but i'm really loving this and", "cb7QXT_VUHE-00054-00036096-00036888": "for this i would probably pair it with uh like a sportier uh bag like this um mz wallace and", "cb7QXT_VUHE-00055-00036944-00037784": "there you go okay so for the next look i wanted to um to style it like i'm going out for drinks", "cb7QXT_VUHE-00056-00037784-00038464": "um this is like a cute little booty and then you can open it up show off some layered", "cb7QXT_VUHE-00057-00038520-00039152": "necklaces and then if you really want to add a little bit of extra for the fall", "cb7QXT_VUHE-00058-00039152-00039840": "winter just add in a felt hat and there you go you are ready to go out and then for the bag", "cb7QXT_VUHE-00059-00039920-00040648": "i mean i even feel like this is great it dresses it up even more the little clutch um and there", "cb7QXT_VUHE-00060-00040648-00041376": "you go cute little outfit for going out it's just so versatile and the other way you can do this um", "cb7QXT_VUHE-00061-00041376-00041984": "you could just put like sneakers on as well or flats and make it a little bit more casual so", "cb7QXT_VUHE-00062-00042048-00042568": "that's why i really like it it's just different and you can style it so many different ways so", "cb7QXT_VUHE-00063-00042568-00043264": "i'm super happy with it and it's super comfortable love it okay so the last item i got from Vici that", "cb7QXT_VUHE-00064-00043264-00043968": "i want to style a few different ways for you is this really pretty satin skirt and i'm so into", "cb7QXT_VUHE-00065-00043968-00044544": "the satin skirts right now because i feel like you really can dress them up or dress them down", "cb7QXT_VUHE-00066-00044544-00045344": "and i'll show you i i promise you can so this i put with heels and a really cute bag and a chunky", "cb7QXT_VUHE-00067-00045344-00045888": "sweater just because it's fall and winter um but i also want to show you like a spring summer look as", "cb7QXT_VUHE-00068-00045888-00046512": "well because these are great skirts for that so these are great because you can also put tights", "cb7QXT_VUHE-00069-00046512-00047192": "on underneath so in the winter you're not freezing um but i really like this look i feel like you're", "cb7QXT_VUHE-00070-00047192-00047856": "so put together but also you are very comfortable like i love this outfit because i like comfort", "cb7QXT_VUHE-00071-00047912-00048560": "and um so yeah so i'm loving the this you could wear this to brunch with your friends you can", "cb7QXT_VUHE-00072-00048560-00049336": "wear this um to a dinner date with your husband happy hour it's i love it it's just perfect and", "cb7QXT_VUHE-00073-00049336-00050032": "i love the neutral tone great for like the winter white feel um so i'm really i'm really happy with", "cb7QXT_VUHE-00074-00050032-00050656": "it so let's try a few different ways that we can um also style it okay so this is another way you", "cb7QXT_VUHE-00075-00050656-00051416": "can wear this so like if it's spring or summer um just put like a camisole or a body suit on and you", "cb7QXT_VUHE-00076-00051416-00052008": "have like it actually looks like a slip dress and then i just paired it with like a cute um", "cb7QXT_VUHE-00077-00052128-00052784": "sandal and yeah and then you just have like a your cute little bit actually this bag will still work", "cb7QXT_VUHE-00078-00052936-00053784": "um again you're sticking with your neutrals but you can even do like a black um a black camisole", "cb7QXT_VUHE-00079-00053784-00054432": "black um like that's what's great about this color you can really mix and match do like a brown tone", "cb7QXT_VUHE-00080-00054432-00055200": "um any any color will match this it's neutral i'm sure you guys know that so um that's just whatever", "cb7QXT_VUHE-00081-00055320-00055984": "so i love it i think it's just super versatile and um again super affordable so i'm just gonna", "cb7QXT_VUHE-00082-00055984-00056584": "try one other look um to really show how you can dress down these types of um skirts", "cb7QXT_VUHE-00083-00056672-00057312": "so this is the last way i'm going to show you and i really love it like i just found a t-shirt in", "cb7QXT_VUHE-00084-00057312-00058016": "my closet it's a nice neutral tone that actually matches this bag and i put some flats on so you're", "cb7QXT_VUHE-00085-00058016-00058672": "really comfortable really casual but you're also really put together and um again it's", "cb7QXT_VUHE-00086-00058672-00059240": "just so easy like i could literally walk out the door run my errands go pick up the kids and i'm", "cb7QXT_VUHE-00087-00059240-00059864": "not gonna i just feel like really put together but i'm also super cash so i am super interested", "cb7QXT_VUHE-00088-00059952-00060416": "super cash super interested in finding out what you guys think about the three", "cb7QXT_VUHE-00089-00060416-00061024": "items that i styled for you let me know what you think about Vici i don't know if you've really", "cb7QXT_VUHE-00090-00061024-00061376": "shopped there but i really have been enjoying what they have lately", "cb7QXT_VUHE-00091-00061440-00062008": "okay so that was my video on my mini vici haul i hope you liked it again please comment down", "cb7QXT_VUHE-00092-00062008-00062672": "below with any questions or any um future videos you'd like me to do i'm happy to read all your", "cb7QXT_VUHE-00093-00062672-00063167": "comments and if you're not a subscriber go ahead and hit that subscribe button and the bell that", "cb7QXT_VUHE-00094-00063167-00063720": "way you never miss any of my videos every week and i hope i see you all next time bye"}}, {"audio_id": "cbVpoH2zhko", "text": {"cbVpoH2zhko-00000-00001501-00003099": "SUBSCRIBE THE CHANNEL FOR NEXT VIDEO"}}, {"audio_id": "cbbhYAzt3JI", "text": {"cbbhYAzt3JI-00000-00000003-00000597": "Hi my name is Dr. Brian MacFalda, and I'm a neurologist at MidMichigan Health. As", "cbbhYAzt3JI-00001-00000597-00000984": "the system stroke director for all of MidMichigan's Medical Centers, I work", "cbbhYAzt3JI-00002-00000984-00001428": "collaboratively with the stroke team and accrediting stroke agencies as well as", "cbbhYAzt3JI-00003-00001428-00002046": "Michigan Medicine to ensure excellent care and better outcomes. My goal is to", "cbbhYAzt3JI-00004-00002046-00002433": "improve the overall quality of healthcare the patient receives by", "cbbhYAzt3JI-00005-00002433-00003035": "implementing a consistent standard of stroke care across the health system. By", "cbbhYAzt3JI-00006-00003035-00003479": "doing this, my hope is to reduce the length of stay and get patients on the", "cbbhYAzt3JI-00007-00003479-00004079": "road to recovery more quickly and reduce the overall cost in the process. In", "cbbhYAzt3JI-00008-00004079-00004491": "addition to being the system stroke director, I also see patients in the", "cbbhYAzt3JI-00009-00004491-00004964": "clinic. My philosophy of patient care is one in which I like to partner with the", "cbbhYAzt3JI-00010-00004964-00005448": "patients. I don't like to tell them what to do, but I do like to educate them on", "cbbhYAzt3JI-00011-00005448-00005907": "the disease process to help them better decide what the best plan of care is for", "cbbhYAzt3JI-00012-00005907-00006411": "them. I may help steer them or direct them if I feel a decision is not in", "cbbhYAzt3JI-00013-00006411-00006759": "their best interest, but I always want them to understand that they do have", "cbbhYAzt3JI-00014-00006759-00007338": "options. In addition to special interests in sports neurology, concussions and", "cbbhYAzt3JI-00015-00007338-00007695": "stroke, I have specialized training in the treatment of", "cbbhYAzt3JI-00016-00007695-00007973": "epilepsy. I find treating epilepsy to be", "cbbhYAzt3JI-00017-00007973-00008445": "fascinating. If we get someone with epilepsy on the right treatment plan, we", "cbbhYAzt3JI-00018-00008445-00008913": "can give them back their independence. I see patients with epilepsy at their", "cbbhYAzt3JI-00019-00008913-00009425": "most vulnerable. These treatments allow them to be better controlled and more", "cbbhYAzt3JI-00020-00009425-00009932": "independent with things like driving or holding down a job -- things that most of", "cbbhYAzt3JI-00021-00009932-00010407": "us take for granted. There are surgical interventions for the treatment of", "cbbhYAzt3JI-00022-00010407-00011031": "epilepsy as well and for those who are good candidates, we typically see an 80 percent", "cbbhYAzt3JI-00023-00011031-00011613": "curative rate. This is one of the few neurologic disease processes that can be", "cbbhYAzt3JI-00024-00011613-00012047": "curative. I really enjoy what I do, because the brain is the body's most", "cbbhYAzt3JI-00025-00012047-00012407": "important organ. It's the last and final frontier of", "cbbhYAzt3JI-00026-00012407-00012831": "medicine, and we are quickly finding out things we could only once dream about.", "cbbhYAzt3JI-00027-00012831-00013322": "And hopefully we will soon have better treatments or cures for neurologic", "cbbhYAzt3JI-00028-00013322-00013679": "diseases that we once thought impossible."}}, {"audio_id": "ccdoyYaAT2c", "text": {"ccdoyYaAT2c-00000-00001313-00001513": "I remember all of it", "ccdoyYaAT2c-00001-00001513-00001975": "and I know I survived", "ccdoyYaAT2c-00002-00001975-00002543": "I just need a moment to clarify everything", "ccdoyYaAT2c-00003-00002543-00002924": "but all of this feels so unreal", "ccdoyYaAT2c-00004-00002924-00003234": "no, it's too good to be true", "ccdoyYaAT2c-00005-00003234-00003752": "after all the anguish that I've been through", "ccdoyYaAT2c-00006-00003752-00003981": "it doesn't feel right", "ccdoyYaAT2c-00007-00003981-00004260": "it's been oddly calm today", "ccdoyYaAT2c-00008-00004260-00004681": "nothing stands in my way", "ccdoyYaAT2c-00009-00004681-00005175": "and the part of me I'm too ashamed to display", "ccdoyYaAT2c-00010-00005175-00005408": "is now wild and free", "ccdoyYaAT2c-00011-00005408-00006028": "first time in forever got the pieces together", "ccdoyYaAT2c-00012-00006028-00006689": "and my knees didn't drop to the ground", "ccdoyYaAT2c-00013-00006689-00007072": "I know what I'm doing", "ccdoyYaAT2c-00014-00007072-00007399": "Down the path that I'm walking", "ccdoyYaAT2c-00015-00007399-00008137": "And I'll try to enjoy all of it", "ccdoyYaAT2c-00016-00008137-00008428": "I remember all of it", "ccdoyYaAT2c-00017-00008428-00008903": "and I know I survived", "ccdoyYaAT2c-00018-00008903-00009527": "being free feels like spreading wings to fly once again", "ccdoyYaAT2c-00019-00009527-00010208": "it feels like a miracle but it's no fairytale", "ccdoyYaAT2c-00020-00010208-00010667": "no white horse or prince, 'cos i saved myself", "ccdoyYaAT2c-00021-00010667-00010912": "and I'd do it again", "ccdoyYaAT2c-00022-00010912-00011244": "I'm not yet in wonderland", "ccdoyYaAT2c-00023-00011244-00011561": "but I'm sure on my journey", "ccdoyYaAT2c-00024-00011561-00011942": "I know some day, I will tell my story", "ccdoyYaAT2c-00025-00011942-00012287": "'bout the stars and the stones", "ccdoyYaAT2c-00026-00012287-00012579": "like the scars on my body", "ccdoyYaAT2c-00027-00012579-00012803": "and my heart do today", "ccdoyYaAT2c-00028-00012803-00013246": "first time in forever", "ccdoyYaAT2c-00029-00013246-00013566": "got the pieces together", "ccdoyYaAT2c-00030-00013566-00014271": "and my knees didn't drop to the ground", "ccdoyYaAT2c-00031-00014271-00014640": "slowly and steady", "ccdoyYaAT2c-00032-00014640-00014972": "stepping forward on my journey", "ccdoyYaAT2c-00033-00014972-00015538": "and I'll try to enjoy all of it", "ccdoyYaAT2c-00034-00015538-00016767": "(instrumental)", "ccdoyYaAT2c-00035-00016767-00017391": "I remember all of it, and I know I survived", "ccdoyYaAT2c-00036-00017391-00018034": "I learned how to be satisfied with who I am", "ccdoyYaAT2c-00037-00018034-00018400": "all my cracks are now mended", "ccdoyYaAT2c-00038-00018400-00018799": "gleaming bright, golden glazed", "ccdoyYaAT2c-00039-00018799-00019217": "it's a piece of myself that I now embrace", "ccdoyYaAT2c-00040-00019217-00019470": "it's who I am"}}, {"audio_id": "cc1wcLyQqKE", "text": {"cc1wcLyQqKE-00000-00001240-00001692": "(children playing)", "cc1wcLyQqKE-00001-00002440-00002984": "How did you get out here?", "cc1wcLyQqKE-00002-00003456-00003800": "No sir, but tonight, I'm gonna make those kids happy", "cc1wcLyQqKE-00003-00003800-00004192": "to have Octavio's Underwater Birthday Song and Ice Cream Birthday Cake!", "cc1wcLyQqKE-00004-00005160-00005784": "Don't worry little fella, I got this", "cc1wcLyQqKE-00005-00006344-00006736": "Okay kids! Are you ready for set sail for the birthday ship?", "cc1wcLyQqKE-00006-00006736-00007184": "I'll give you the one and only Octavio Octopus and is underwater friends!", "cc1wcLyQqKE-00007-00007240-00007800": "Sarah the Seahorse and Melanie the Mermaid! so sit back and relax and enjoy the show!", "cc1wcLyQqKE-00008-00008456-00009192": "Hello kids I'm Octavio the Octopus I have something for especially for the underwater", "cc1wcLyQqKE-00009-00009192-00010184": "birthday today and I just remember to try to change my diapers for anything Um.. Wow!", "cc1wcLyQqKE-00010-00010416-00011384": "Okay little guppies just sing with me! Happy..", "cc1wcLyQqKE-00011-00012276-00012376": "Incoming!", "cc1wcLyQqKE-00012-00012376-00012784": "Oh No!", "cc1wcLyQqKE-00013-00013160-00013719": "rachel not good"}}, {"audio_id": "cd1eKKQjHGE", "text": {"cd1eKKQjHGE-00000-00001268-00001572": "my name is Joe Lazzarini and I'm a grassroots coordinator with the", "cd1eKKQjHGE-00001-00001572-00001773": "Coalition for social justice", "cd1eKKQjHGE-00002-00001773-00002083": "Coalition for social justice is a I", "cd1eKKQjHGE-00003-00002083-00002508": "grassroots aggressive nonprofit organization and I'm and that we work on", "cd1eKKQjHGE-00004-00002508-00002927": "issues that primarily affects folks and hot low-income communities", "cd1eKKQjHGE-00005-00002927-00003379": "so we have offices in Fall River New Bedford Brockton and Falmouth", "cd1eKKQjHGE-00006-00003379-00003711": "right now we're out right now we're working on our a statewide campaign", "cd1eKKQjHGE-00007-00003711-00003865": "called raise up Massachusetts", "cd1eKKQjHGE-00008-00003865-00004267": "and raise up Massachusetts is a coalition of organizations around Massachusetts", "cd1eKKQjHGE-00009-00004267-00004419": "that is working to", "cd1eKKQjHGE-00010-00004419-00004807": "raise the state's minimum wage to at least $10.50 an hour and then tie it to", "cd1eKKQjHGE-00011-00004807-00005113": "the rising cost of living so that people are able to care for themselves and", "cd1eKKQjHGE-00012-00005113-00005198": "their family as", "cd1eKKQjHGE-00013-00005198-00005519": "I mean other when people are more money in their pockets are spending that money", "cd1eKKQjHGE-00014-00005519-00005678": "and fueling the state's economy", "cd1eKKQjHGE-00015-00005678-00005996": "and the other issue that we're working on is earn paid sick time", "cd1eKKQjHGE-00016-00005996-00006277": "when people get sick they need to be able to stay home and take care", "cd1eKKQjHGE-00017-00006277-00006458": "themselves and their family members", "cd1eKKQjHGE-00018-00006458-00006819": "because we don't want people going to work sick and people shouldnt A. lose a", "cd1eKKQjHGE-00019-00006819-00006894": "day's pay", "cd1eKKQjHGE-00020-00006894-00007227": "just because they got sick the shouldn't  be the most certainly shouldn't be fired from", "cd1eKKQjHGE-00021-00007227-00007391": "there job forgetting sick", "cd1eKKQjHGE-00022-00007391-00007709": "you know in order for this campaign to work it's a boots on the ground", "cd1eKKQjHGE-00023-00007709-00008094": "and this is a statewide effort and the colour from a social justice is based in", "cd1eKKQjHGE-00024-00008094-00008241": "southeastern Massachusetts", "cd1eKKQjHGE-00025-00008241-00008631": "we have show 230 thousand signatures that we need to connect from around the", "cd1eKKQjHGE-00026-00008631-00008688": "state", "cd1eKKQjHGE-00027-00008688-00009020": "this fall between September 16 November 20th", "cd1eKKQjHGE-00028-00009020-00009392": "and that's gonna take thousands of grassroots volunteers willing to go out and", "cd1eKKQjHGE-00029-00009392-00009517": "collecting signatures", "cd1eKKQjHGE-00030-00009517-00009869": "to place these items on next november state ballot", "cd1eKKQjHGE-00031-00009869-00010170": "somebody who went to Bristol Community College in Attlboro I I firmly believe", "cd1eKKQjHGE-00032-00010170-00010234": "that", "cd1eKKQjHGE-00033-00010234-00010619": "service starts at school in our organization the Coalition for social", "cd1eKKQjHGE-00034-00010619-00010676": "justice", "cd1eKKQjHGE-00035-00010676-00011007": "was actually founded by two professors here first a community", "cd1eKKQjHGE-00036-00011007-00011061": "college", "cd1eKKQjHGE-00037-00011061-00011399": "got Daniel Bar in Molly Impalik who both teach in New Bedford", "cd1eKKQjHGE-00038-00011399-00011682": "so Bristol Community College", "cd1eKKQjHGE-00039-00011682-00012014": "is absolutely committed to the hard work that", "cd1eKKQjHGE-00040-00012014-00012279": "that we're doing to to raise up Massachusetts"}}, {"audio_id": "cdfHIteair8", "text": {}}, {"audio_id": "cdvsvB5wWRA", "text": {"cdvsvB5wWRA-00000-00007093-00007853": "Good morning, mr, master, maestro or simply", "cdvsvB5wWRA-00001-00007853-00008353": "or", "cdvsvB5wWRA-00002-00008353-00008986": "simply David, yes David, why not David, David Lynch?", "cdvsvB5wWRA-00003-00008986-00009693": "It's November 5th, 2022 and  it's a Saturday.", "cdvsvB5wWRA-00004-00009793-00010697": "Here in Naples... \"Remember for ever the 5th of November\", this legendary quote from", "cdvsvB5wWRA-00005-00010697-00011014": "the movie V for Vendetta (2005).", "cdvsvB5wWRA-00006-00011014-00012623": "Here in Naples a clear.. no sorry haha, a totally gray, dark, cloudy sky, 60.8 fahrenheit 16 celsius", "cdvsvB5wWRA-00007-00012623-00013091": "and this means that it's that day really, really, really, really soft like in these", "cdvsvB5wWRA-00008-00013091-00013191": "days and in this", "cdvsvB5wWRA-00009-00013191-00013811": "period even if not at all because we have few degrees less in comparison of the standard.", "cdvsvB5wWRA-00010-00013811-00014603": "And so this means that it seems a bit a Winter atmosphere than Autumn atmosphere.", "cdvsvB5wWRA-00011-00014603-00016015": "However in general it's a good, good atmosphere, good I mean only as regard the degrees.", "cdvsvB5wWRA-00012-00016015-00017000": "This afternoon I think that the temperature will be the same, it might as well rise by", "cdvsvB5wWRA-00013-00017000-00017462": "some degree, obviously we are not magicians or wizards on this point as you know,", "cdvsvB5wWRA-00014-00017462-00018118": "but the really important thing with this atmosphere is that in this moment we don't have", "cdvsvB5wWRA-00015-00018118-00018587": "absolutely but I think also in general for all the day those beautiful blue skies and", "cdvsvB5wWRA-00016-00018587-00018687": "golden", "cdvsvB5wWRA-00017-00018687-00018787": "sunshine.", "cdvsvB5wWRA-00018-00018787-00019335": "As I said there's a totally dark atmosphere", "cdvsvB5wWRA-00019-00019335-00020379": "and yes it's also raining, we hope for a better climate directly tomorrow but I don't know.", "cdvsvB5wWRA-00020-00020379-00021090": "I think accordin to what I read also tomorrow and in the next days will be in this way.", "cdvsvB5wWRA-00021-00021090-00021237": "So, we'll see.", "cdvsvB5wWRA-00022-00021237-00021431": "Well, so said this:", "cdvsvB5wWRA-00023-00021431-00022209": "so from the mythical window with the new courtain, gray as you know with these beautiful", "cdvsvB5wWRA-00024-00022209-00022358": "painted wavy branches", "cdvsvB5wWRA-00025-00022358-00023337": "and its green roller shooter, not visible in this period and in fact here in the shot", "cdvsvB5wWRA-00026-00023337-00024063": "and finally from my mythical keyboard Yamaha DGX640, YPG, YPG-625", "cdvsvB5wWRA-00027-00024363-00024639": "Have a great day to him, all the people who follow the channel and the Weathers, yes,", "cdvsvB5wWRA-00028-00024639-00025329": "really a greeting to everyone, also to my brother and finally I hope you all have a 0:04:13.290,1193:02:47.295 great", "cdvsvB5wWRA-00029-00025429-00025529": "breakfast.", "cdvsvB5wWRA-00030-00025529-00025657": "I'll do it as soon, I'm really hungry.", "cdvsvB5wWRA-00031-00025657-00026035": "Breakfast is always one of the most beautiful", "cdvsvB5wWRA-00032-00026035-00026400": "things in the life and in the world.", "cdvsvB5wWRA-00033-00026400-00026633": "I'll see you tomorrow."}}, {"audio_id": "cdG4oUzYuio", "text": {"cdG4oUzYuio-00000-00000024-00000384": "(groovy instrumental music)", "cdG4oUzYuio-00001-00000384-00000583": "- All right, so what I'll show you guys is inside work", "cdG4oUzYuio-00002-00000583-00000800": "of how I put this commercial together.", "cdG4oUzYuio-00003-00000800-00001141": "So this video is something we shot for a lawyer.", "cdG4oUzYuio-00004-00001141-00001326": "It's a simple fall commercial and to put", "cdG4oUzYuio-00005-00001326-00001607": "this whole thing together, I had to find a supermarket", "cdG4oUzYuio-00006-00001607-00001870": "that allowed us to actually shoot at their location,", "cdG4oUzYuio-00007-00001870-00002032": "and those big chains wouldn't work,", "cdG4oUzYuio-00008-00002032-00002193": "so what I actually did was I looking", "cdG4oUzYuio-00009-00002193-00002547": "for local produce places that we could", "cdG4oUzYuio-00010-00002547-00002926": "actually potentially barter with them to do the video", "cdG4oUzYuio-00011-00002926-00003256": "and then we ended up finding this one place (mumbles).", "cdG4oUzYuio-00012-00003256-00003500": "I actually had to give him money on top", "cdG4oUzYuio-00013-00003500-00003777": "of actually doing photos for them in exchange", "cdG4oUzYuio-00014-00003777-00004033": "for them to let us use the location for four hours.", "cdG4oUzYuio-00015-00004121-00004360": "We're waiting for the store to close in about 30 minutes", "cdG4oUzYuio-00016-00004360-00004517": "and we're gonna get it rolling.", "cdG4oUzYuio-00017-00004517-00004672": "All right, so for today's lighting,", "cdG4oUzYuio-00018-00004672-00005172": "we're using Aputure 120B mark one and Aputure 120B mark two.", "cdG4oUzYuio-00019-00005196-00005376": "We're about 10 minutes before we can", "cdG4oUzYuio-00020-00005376-00005649": "actually start shooting when the place closes.", "cdG4oUzYuio-00021-00005649-00005762": "Something else you wanna do when you're working", "cdG4oUzYuio-00022-00005762-00005926": "with a very limited amount of time", "cdG4oUzYuio-00023-00005926-00006101": "is you wanna maximize your time.", "cdG4oUzYuio-00024-00006101-00006555": "So for this, what I did is that we had about 45 minutes", "cdG4oUzYuio-00025-00006555-00006866": "since the time we got there to start setting up everything,", "cdG4oUzYuio-00026-00006866-00007231": "but we couldn't start shooting until everyone actually left,", "cdG4oUzYuio-00027-00007231-00007509": "so for this itself, we actually shot on a Sunday", "cdG4oUzYuio-00028-00007509-00007862": "where the grocery store closed at five o'clock", "cdG4oUzYuio-00029-00007862-00008142": "and we got in at 4:30 to start setting up,", "cdG4oUzYuio-00030-00008142-00008458": "but as always, people showed in a little bit late.", "cdG4oUzYuio-00031-00008458-00008658": "We weren't able to start shooting when we were supposed", "cdG4oUzYuio-00032-00008658-00008927": "to start shooting, so I took advantage of the time", "cdG4oUzYuio-00033-00008927-00009161": "to start getting my mic to pick up sounds.", "cdG4oUzYuio-00034-00009161-00009421": "Now we're gonna do a little bit of sound design", "cdG4oUzYuio-00035-00009421-00009584": "and we're actually gonna record audio", "cdG4oUzYuio-00036-00009584-00009773": "of them actually ringing up stuff,", "cdG4oUzYuio-00037-00009773-00010109": "just so we have that for the video.", "cdG4oUzYuio-00038-00010109-00010322": "When the music's gone, something else that I'm gonna get", "cdG4oUzYuio-00039-00010322-00010550": "is gonna be room tone, just to be able to add that", "cdG4oUzYuio-00040-00010550-00010842": "for the video, you don't wanna have as much no noise", "cdG4oUzYuio-00041-00010842-00011201": "in the background, but getting the noise of the AC", "cdG4oUzYuio-00042-00011201-00011495": "and just kinda the environment here really helps you", "cdG4oUzYuio-00043-00011495-00011778": "set the level of production for the commercial.", "cdG4oUzYuio-00044-00011778-00011913": "Can I ask you a favor? - Yeah.", "cdG4oUzYuio-00045-00011913-00012146": "- Can I have you ring up some stuff?", "cdG4oUzYuio-00046-00012146-00012348": "(electronic pinging)", "cdG4oUzYuio-00047-00012348-00012570": "And then bag, put something in your bag in there.", "cdG4oUzYuio-00048-00012570-00012723": "- Oh, okay. - Perfect.", "cdG4oUzYuio-00049-00012723-00013032": "(electronic pinging)", "cdG4oUzYuio-00050-00013138-00013285": "- Dawn, pick up at Produce.", "cdG4oUzYuio-00051-00013496-00013735": "- How's that sound? - Good, you're a pro.", "cdG4oUzYuio-00052-00013735-00014033": "- So we ended up using this little bit for the intro.", "cdG4oUzYuio-00053-00014033-00014310": "When you see the video at the end where you see the lady", "cdG4oUzYuio-00054-00014310-00014654": "start shopping, you hear her giving this little talk,", "cdG4oUzYuio-00055-00014654-00014980": "saying, \"Hey, Dawn, we have a produce spill.\"", "cdG4oUzYuio-00056-00014980-00015386": "All right, yeah, so I wanna have you come here, Trace.", "cdG4oUzYuio-00057-00015386-00015663": "Remember, when I'll call you, your action,", "cdG4oUzYuio-00058-00015663-00015947": "this is just like a dry run.", "cdG4oUzYuio-00059-00015947-00016244": "So this part here, I pretty much wanted to go over", "cdG4oUzYuio-00060-00016244-00016510": "with the talent what I was actually looking for them to do", "cdG4oUzYuio-00061-00016510-00016738": "versus just telling them what I wanted them to do,", "cdG4oUzYuio-00062-00016738-00017052": "I actually went and actually showed them.", "cdG4oUzYuio-00063-00017052-00017300": "This really helps to make sure that everyone's", "cdG4oUzYuio-00064-00017300-00017643": "on the same page, but you being a director,", "cdG4oUzYuio-00065-00017643-00017950": "you really wanna show them what you're looking for.", "cdG4oUzYuio-00066-00017950-00018300": "(groovy electronic music)", "cdG4oUzYuio-00067-00019072-00019155": "Action.", "cdG4oUzYuio-00068-00019257-00019342": "Oh, that's great.", "cdG4oUzYuio-00069-00019631-00019746": "- [Man] (muffled speaking) helpful?", "cdG4oUzYuio-00070-00019746-00020035": "- So other thing I wanna say about shooting that location", "cdG4oUzYuio-00071-00020035-00020306": "is that leave the place better than how you found it.", "cdG4oUzYuio-00072-00020461-00020679": "Be very friendly to all the staff who're working there.", "cdG4oUzYuio-00073-00020679-00020889": "You wanna build relationships with people.", "cdG4oUzYuio-00074-00021277-00021453": "It's essential for you to be able to show", "cdG4oUzYuio-00075-00021453-00021732": "different perspectives by using different lenses.", "cdG4oUzYuio-00076-00021732-00022232": "Most of everything we shot was on a 35 Sigma Art Lens", "cdG4oUzYuio-00077-00022250-00022601": "and for a lot of closeups that when you see her grabbing", "cdG4oUzYuio-00078-00022601-00023086": "for fruit, that's either done on an 85 1.8 or on a 51.8", "cdG4oUzYuio-00079-00023086-00023480": "and that's just really to give the different perspectives.", "cdG4oUzYuio-00080-00023480-00023694": "Yeah, so another big thing with this,", "cdG4oUzYuio-00081-00023694-00023930": "since I knew we were gonna do a green screen", "cdG4oUzYuio-00082-00023930-00024261": "for the end of the video, I took the time to actually shoot", "cdG4oUzYuio-00083-00024261-00024761": "a frame that was just a still shot that I could actually use", "cdG4oUzYuio-00084-00024762-00025018": "to put the lawyer as a dropback.", "cdG4oUzYuio-00085-00025018-00025268": "Other than that, so the project's super successful.", "cdG4oUzYuio-00086-00025268-00025435": "We ended up working with a series of three", "cdG4oUzYuio-00087-00025435-00025683": "of these different Oooo Moments for the client,", "cdG4oUzYuio-00088-00025683-00026094": "which are all airing now or will be airing now in 2020.", "cdG4oUzYuio-00089-00026094-00026298": "- That's it. - Yep, it's a wrap.", "cdG4oUzYuio-00090-00026410-00026614": "Thanks a lot, buddy. - All right.", "cdG4oUzYuio-00091-00026614-00026762": "- All right, just so I wrap everything up.", "cdG4oUzYuio-00092-00026762-00026904": "All right, guys, thanks for watching.", "cdG4oUzYuio-00093-00026904-00027093": "Make sure to hit Like, comment and subscribe,", "cdG4oUzYuio-00094-00027093-00027270": "and if you want any more helpful tips,", "cdG4oUzYuio-00095-00027270-00027451": "make sure to leave a comment so we know what to do", "cdG4oUzYuio-00096-00027451-00027651": "for the next video, thanks for watching.", "cdG4oUzYuio-00097-00027747-00027908": "(upbeat instrumental music)", "cdG4oUzYuio-00098-00027908-00028178": "- [Cashier] Dawn, cleanup at produce aisle.", "cdG4oUzYuio-00099-00028178-00028598": "♪ Somewhere on the scene ♪", "cdG4oUzYuio-00100-00028598-00028816": "♪ It get a little longer, so it seems ♪", "cdG4oUzYuio-00101-00028816-00028949": "(air whooshes)", "cdG4oUzYuio-00102-00028949-00029096": "(record scratches) - Ooh.", "cdG4oUzYuio-00103-00029096-00029377": "(woman groans softly) (dramatic music)", "cdG4oUzYuio-00104-00029377-00029564": "- Hi, I'm attorney Lance Rudzinski", "cdG4oUzYuio-00105-00029564-00029860": "from RTR Law, a full-service law firm.", "cdG4oUzYuio-00106-00029860-00030102": "We handle all of your personal injury cases.", "cdG4oUzYuio-00107-00030102-00030368": "For those Oooo Moments, give us a call.", "cdG4oUzYuio-00108-00030368-00030716": "Retain The Flame. (dramatic music)"}}, {"audio_id": "cdVmn3WggR8", "text": {"cdVmn3WggR8-00000-00000006-00000279": "Hello, internet. And welcome back to the channel. My name is mark.", "cdVmn3WggR8-00001-00000279-00000621": "If you don't know me already, and today we're back with another typing video,", "cdVmn3WggR8-00002-00000621-00000953": "but it's a little different today. So I was reached out by a,", "cdVmn3WggR8-00003-00000955-00001173": "the company behind waver, a typing adventure,", "cdVmn3WggR8-00004-00001173-00001569": "a new typing game that just came out on steam and they sent me a free steam key", "cdVmn3WggR8-00005-00001569-00001662": "and wanted me to check it out.", "cdVmn3WggR8-00006-00001673-00002103": "So today is going to be sort of a little mix of a gaming video,", "cdVmn3WggR8-00007-00002103-00002562": "but also because I've been interested in looking into typing games,", "cdVmn3WggR8-00008-00002562-00002847": "because I want to make one of my own. If you don't already know,", "cdVmn3WggR8-00009-00002847-00003321": "I had a dev log running for several months and while I'm doing art and learning", "cdVmn3WggR8-00010-00003321-00003611": "the ins and outs of things, I thought making a small type game would be cool.", "cdVmn3WggR8-00011-00003636-00003849": "So in the commentary here,", "cdVmn3WggR8-00012-00003849-00004257": "we'll also be exploring what this game does differently from other games I've", "cdVmn3WggR8-00013-00004257-00004539": "used or websites I've used explicitly to practice.", "cdVmn3WggR8-00014-00004548-00004848": "I recently made a video about the gamification on language learning apps.", "cdVmn3WggR8-00015-00004890-00005262": "And so I want to see in this game itself, you know,", "cdVmn3WggR8-00016-00005262-00005676": "it's not really meant as a tool from what I understand from the advertising,", "cdVmn3WggR8-00017-00005679-00005901": "but more so as a game. So just really quick,", "cdVmn3WggR8-00018-00005901-00006204": "they're not paying me or I'm not affiliated with this company.", "cdVmn3WggR8-00019-00006213-00006483": "This video is more or less first impressions and whatnot.", "cdVmn3WggR8-00020-00006486-00006804": "They timed this very well. I'll say that. And if throughout the video,", "cdVmn3WggR8-00021-00006804-00007206": "you're curious at all to check the game out yourself, it's currently on sale.", "cdVmn3WggR8-00022-00007230-00007290": "Um,", "cdVmn3WggR8-00023-00007290-00007527": "so I'll leave a link to the steam page in the description down below when it's", "cdVmn3WggR8-00024-00007527-00007884": "on sale till the end of the week. All right. I will say, oh,", "cdVmn3WggR8-00025-00008006-00008277": "they got a little customization going on here. I'm a Cordy guy though.", "cdVmn3WggR8-00026-00008277-00008676": "What can I say? Can squad brilliant. We'll sit. Ooh,", "cdVmn3WggR8-00027-00008697-00008982": "I do like to look at this. I will admit now, if you don't know me already,", "cdVmn3WggR8-00028-00008982-00009192": "you're coming across this channel for the first time. I,", "cdVmn3WggR8-00029-00009234-00009564": "the biggest videos on my channel are typing videos and I can type it on an", "cdVmn3WggR8-00030-00009567-00010062": "average of 170 words per minute. Eric keys to select, enter, to confirm, uh,", "cdVmn3WggR8-00031-00010071-00010452": "easygoing for beginners, more challenging for seasoned players.", "cdVmn3WggR8-00032-00010509-00010770": "I'm not a seasoned the player, but we're going to do it. Anyway.", "cdVmn3WggR8-00033-00010827-00011049": "The stadium homes with anticipation is the home team.", "cdVmn3WggR8-00034-00011049-00011517": "Kin squad seems poised to win the world championship series pre", "cdVmn3WggR8-00035-00011517-00011586": "cup.", "cdVmn3WggR8-00036-00011586-00011907": "The fans prepare to spur their heroes through the last few minutes with their", "cdVmn3WggR8-00037-00011907-00012135": "seats wave.", "cdVmn3WggR8-00038-00012225-00012483": "It's really cool to look into various typing games.", "cdVmn3WggR8-00039-00012489-00012672": "I have an idea of a premise I want to make,", "cdVmn3WggR8-00040-00012672-00013035": "but it kind of just copies ones that I used in middle school, uh,", "cdVmn3WggR8-00041-00013038-00013397": "to learn how to type and whatnot. And so seeing a full on game,", "cdVmn3WggR8-00042-00013397-00013740": "that's like brand new and has this influence aesthetic.", "cdVmn3WggR8-00043-00014025-00014319": "Okay. Oh,", "cdVmn3WggR8-00044-00014654-00015091": "I decided not to do like, oh, oh, you have to good job, mark.", "cdVmn3WggR8-00045-00015347-00015644": "Um, okay.", "cdVmn3WggR8-00046-00015701-00015962": "I decided to not Frank, wait, what is this one?", "cdVmn3WggR8-00047-00016572-00016863": "Did I miss something? Wait, wait, wait, wait, what did I miss?", "cdVmn3WggR8-00048-00016999-00017497": "I did not connect the dots that the people are in the exact", "cdVmn3WggR8-00049-00017497-00017904": "layout as the keyboard is, which is a little strange to me", "cdVmn3WggR8-00050-00018343-00018526": "because it doesn't give you like a letter to hit.", "cdVmn3WggR8-00051-00019554-00019875": "So I guess this is getting familiarity with the way the game or", "cdVmn3WggR8-00052-00020427-00020754": "I'm sorry. Wait, what? There's no shot.", "cdVmn3WggR8-00053-00022231-00022468": "I'm a little bit welded. Um, I could see this.", "cdVmn3WggR8-00054-00022498-00022956": "I feel like I have to be intentional to lose. It's cool. Seeing like a,", "cdVmn3WggR8-00055-00022957-00023077": "a deep story into it.", "cdVmn3WggR8-00056-00023077-00023542": "It's not just like you have to run fast and then type it all up and hoping it", "cdVmn3WggR8-00057-00023542-00023625": "picks up a bit though.", "cdVmn3WggR8-00058-00024103-00024186": "Oh, is this New York?", "cdVmn3WggR8-00059-00024895-00025393": "They couldn't do the wave at all. I'm curious if that's,", "cdVmn3WggR8-00060-00025562-00025604": "you know,", "cdVmn3WggR8-00061-00025604-00026083": "something I've seen in games before and I'm personally a fan of it is 40 years", "cdVmn3WggR8-00062-00026089-00026173": "later.", "cdVmn3WggR8-00063-00026239-00026720": "I'm seeing them like give you something that you would only be able to do", "cdVmn3WggR8-00064-00026720-00026995": "when you get to later in the game.", "cdVmn3WggR8-00065-00027247-00027436": "So I'm curious if you were supposed to be able to do that,", "cdVmn3WggR8-00066-00027436-00027607": "but there was a lot happening right there. Right.", "cdVmn3WggR8-00067-00027613-00028057": "So I imagine is this like a more than world cup loss reform team?", "cdVmn3WggR8-00068-00028060-00028558": "Wait for decades. All right.", "cdVmn3WggR8-00069-00028558-00028810": "I'm ready. Type the sentence.", "cdVmn3WggR8-00070-00028999-00029082": "Literally that sentence", "cdVmn3WggR8-00071-00029626-00029709": "indeed.", "cdVmn3WggR8-00072-00030541-00030907": "Okay. It doesn't really average word time. 48 seconds.", "cdVmn3WggR8-00073-00030976-00031360": "1 24. I can do better than that. I think I was startled by the fact that it had,", "cdVmn3WggR8-00074-00031360-00031833": "um, like a multiple phases. They do have limits for that.", "cdVmn3WggR8-00075-00031833-00032206": "I think membrane keyboards are worse at that ghosting or whatever.", "cdVmn3WggR8-00076-00032383-00032713": "I'm ready. I'm ready. Fallen from grace.", "cdVmn3WggR8-00077-00032833-00033103": "So is this where words are going to come up now or not", "cdVmn3WggR8-00078-00033316-00033613": "full control? What can I say? Oh, I, oh,", "cdVmn3WggR8-00079-00033613-00033817": "I think I'm supposed to actually do it in the right order though.", "cdVmn3WggR8-00080-00033988-00034435": "Time is not mine to command quite yet. Oh,", "cdVmn3WggR8-00081-00034435-00034858": "the people with the scarves are the home row keys. I didn't notice that", "cdVmn3WggR8-00082-00035084-00035204": "this is very fascinating", "cdVmn3WggR8-00083-00035726-00036158": "because the F and J that's very helpful actually, because you know,", "cdVmn3WggR8-00084-00036158-00036302": "through this whole, uh, whoops.", "cdVmn3WggR8-00085-00036709-00037063": "Oh, nice. Good job, mark. All right.", "cdVmn3WggR8-00086-00037147-00037237": "I think we won.", "cdVmn3WggR8-00087-00037552-00038020": "Can squad represent. I'm kind of curious what the, um,", "cdVmn3WggR8-00088-00038289-00038412": "what the beginner version is.", "cdVmn3WggR8-00089-00038746-00039169": "Get ready to type. Okay. This is kind of cool.", "cdVmn3WggR8-00090-00040476-00040845": "1 35, slightly better. It's weird. Cause the, when it switches,", "cdVmn3WggR8-00091-00040845-00041181": "it takes me an extra second or two to like think it through.", "cdVmn3WggR8-00092-00041220-00041544": "Let me try type as mode. Cause that might be what I'm thinking. This is.", "cdVmn3WggR8-00093-00041839-00042220": "Okay. So that was story mode. What does typer, okay. I'm ready to type,", "cdVmn3WggR8-00094-00042733-00043179": "whoops. Wow. Look at all the achievements on the bottom. Right. Um,", "cdVmn3WggR8-00095-00043191-00043662": "okay. Okay. So there's a straightforward typer requires 10 stars.", "cdVmn3WggR8-00096-00043734-00044172": "Um, let me change. The type of smoke was that Barkin banker's club,", "cdVmn3WggR8-00097-00044211-00044445": "serious milestones we edit is better because I think maybe,", "cdVmn3WggR8-00098-00044445-00044745": "maybe classic mode is a different version of this game.", "cdVmn3WggR8-00099-00044799-00045165": "That's kind of like just keyboard layout. It is kind of nice. Cause you get to,", "cdVmn3WggR8-00100-00045171-00045537": "it's trying to teach you the keys relative to each other, but nevermind.", "cdVmn3WggR8-00101-00045651-00046134": "This is the same exact thing. All right. We'll,", "cdVmn3WggR8-00102-00046134-00046228": "we'll play through this,", "cdVmn3WggR8-00103-00046252-00046606": "but I do find that quite fascinating that it's kind of like giving you the", "cdVmn3WggR8-00104-00046606-00046888": "letters because even though I consider myself a fast typist,", "cdVmn3WggR8-00105-00046948-00047209": "I imagine most of these games are trying to get you better at typing.", "cdVmn3WggR8-00106-00047260-00047608": "And this is, I think the first time I've seen something,", "cdVmn3WggR8-00107-00047608-00047938": "approach it in a relative sense. Uh,", "cdVmn3WggR8-00108-00047944-00048394": "in other words like this mode clearly is saying, here are the keys to hit,", "cdVmn3WggR8-00109-00048484-00048754": "but I suppose I was like expecting more of a, uh,", "cdVmn3WggR8-00110-00049053-00049236": "when you do the wave, do you have to type a word out?", "cdVmn3WggR8-00111-00049236-00049715": "Because I could see that working in a sense I'm very fascinated.", "cdVmn3WggR8-00112-00049717-00050040": "This whole relative positioning idea. I don't know if that's like intentional.", "cdVmn3WggR8-00113-00050067-00050358": "So I guess I walked in with the expectation that it was gonna be like type the", "cdVmn3WggR8-00114-00050358-00050754": "word. Hello, but it is cool. Cause it's like a guitar here, but with a keyboard,", "cdVmn3WggR8-00115-00050754-00051246": "I guess, mechanically speaking, because your,", "cdVmn3WggR8-00116-00051246-00051741": "your ability to type fast doesn't really come in at all. Again,", "cdVmn3WggR8-00117-00051741-00051999": "I like the little touch of the scarf thing that makes it very easy to get", "cdVmn3WggR8-00118-00051999-00052047": "around.", "cdVmn3WggR8-00119-00052047-00052359": "Maybe the thing that I felt at the start is something you're supposed to get", "cdVmn3WggR8-00120-00052359-00052677": "done. Oh,", "cdVmn3WggR8-00121-00052677-00052923": "next to G that's cool.", "cdVmn3WggR8-00122-00052991-00053204": "I will say it's just a different approach and I like it.", "cdVmn3WggR8-00123-00053226-00053630": "I let her next to G like you don't, you don't really about that all that much.", "cdVmn3WggR8-00124-00053640-00053907": "Oh, I hit the bracket by accident, but does it get harder?", "cdVmn3WggR8-00125-00053907-00054291": "Do they add in the brackets? Do you think he says to himself in his room, wow.", "cdVmn3WggR8-00126-00054291-00054666": "I have to keep looking at the keyboard because I don't know what the relative", "cdVmn3WggR8-00127-00054666-00054822": "positioning is. This is, this is,", "cdVmn3WggR8-00128-00054822-00055217": "so this is so strange next to X there's like there are games where, you know,", "cdVmn3WggR8-00129-00055217-00055524": "words pop up and as a fast typer, those games, don't,", "cdVmn3WggR8-00130-00055533-00055817": "they're really good for learning, right? But there's a,", "cdVmn3WggR8-00131-00055817-00056076": "there's a cap one game that I love a,", "cdVmn3WggR8-00132-00056077-00056291": "a game that comes in waves and the faster you can type words,", "cdVmn3WggR8-00133-00056291-00056417": "the more waves you can get through,", "cdVmn3WggR8-00134-00056457-00056724": "but there's also a threshold there cause it gets redundant. So, you know,", "cdVmn3WggR8-00135-00056724-00057153": "how can we take this combination of increasing difficulty over time with", "cdVmn3WggR8-00136-00057153-00057438": "something that's still fun to play? Um,", "cdVmn3WggR8-00137-00057446-00057708": "maybe I will discuss my idea at the end of the video, but we'll keep going.", "cdVmn3WggR8-00138-00057708-00057840": "Cause I do want to get to the typer mode.", "cdVmn3WggR8-00139-00058622-00058778": "I don't know where to look for this and this to start", "cdVmn3WggR8-00140-00059624-00059985": "1 26, a Bismal. I think they do count the,", "cdVmn3WggR8-00141-00059985-00060254": "the half second or so of when it switches. I don't know.", "cdVmn3WggR8-00142-00060254-00060695": "I think it's a good thing to learn. You know, if I'm at GNH,", "cdVmn3WggR8-00143-00060776-00061073": "you know, which finger should I use to hit those? Cause for example, ghost,", "cdVmn3WggR8-00144-00061121-00061553": "I guess I would do G with the left pointer, a took the right pointer and oh,", "cdVmn3WggR8-00145-00061553-00062005": "with the right ring finger. So gho, but what if the word involves an E", "cdVmn3WggR8-00146-00062186-00062491": "and I should do G with the right pointer finger or something.", "cdVmn3WggR8-00147-00062588-00063086": "So it totally tackles muscle memory from a different point", "cdVmn3WggR8-00148-00063086-00063466": "of view, I guess you could say. Cause it kinda like what's whoops.", "cdVmn3WggR8-00149-00063505-00063829": "What's three from the right, you know, what's five from the left", "cdVmn3WggR8-00150-00064141-00064376": "three from the Frick out of order.", "cdVmn3WggR8-00151-00064532-00064766": "What up gamers? Oh, full control. Let's go.", "cdVmn3WggR8-00152-00065259-00065727": "Perfect. I thought I didn't realize this was going to be so, uh, focus,", "cdVmn3WggR8-00153-00065727-00066156": "grabbing Frank next to FSG in the depth I love, I love the scarf.", "cdVmn3WggR8-00154-00066156-00066480": "That's such a small detail, but incredibly useful.", "cdVmn3WggR8-00155-00066531-00066882": "It's funny that I did so well on the one where you can see the letters.", "cdVmn3WggR8-00156-00066882-00067167": "Cause it, it accidentally,", "cdVmn3WggR8-00157-00067167-00067603": "it shows me how much of a difference it makes of like, you know, if it,", "cdVmn3WggR8-00158-00067603-00067947": "if it's an F I just hit F but if it's all relative", "cdVmn3WggR8-00159-00068220-00068343": "that I didn't expect that", "cdVmn3WggR8-00160-00068625-00068922": "because you also what's nice is that you really can't look at the keyboard for", "cdVmn3WggR8-00161-00068922-00069005": "this.", "cdVmn3WggR8-00162-00069210-00069621": "Cause you need to see the wave timing really by headlamps,", "cdVmn3WggR8-00163-00069621-00069849": "by batteries for presence, claustrophobia. Okay.", "cdVmn3WggR8-00164-00069951-00070299": "Remember if you control before events get ready to type, okay.", "cdVmn3WggR8-00165-00070299-00070425": "We're going to break one 50 right here.", "cdVmn3WggR8-00166-00071311-00071614": "In fall. The ball, there are goals.", "cdVmn3WggR8-00167-00071726-00072067": "This is literally me with sports. You do know. Is that a.", "cdVmn3WggR8-00168-00072436-00072915": "Bismal? A Bismal. We're doing that again. Knocking me out here.", "cdVmn3WggR8-00169-00072969-00073107": "Come on chief. Go, go back.", "cdVmn3WggR8-00170-00073597-00073801": "That, that one second hesitation does throw me off,", "cdVmn3WggR8-00171-00073804-00074251": "but I'm not realizing how helpful the cursor is on like other websites.", "cdVmn3WggR8-00172-00074275-00074713": "All right. Last one. We'll wrap it up with some thoughts, you know, is,", "cdVmn3WggR8-00173-00074731-00074929": "will this be good if you want to get better at typing?", "cdVmn3WggR8-00174-00075073-00075367": "The key on the timing is to definitely not look at the keyboard,", "cdVmn3WggR8-00175-00075523-00075841": "but that not gonna lie. It's kinda, it's kinda tough.", "cdVmn3WggR8-00176-00075925-00076108": "I got to rely on the scarf boys.", "cdVmn3WggR8-00177-00076360-00076693": "Didn't see that one. All right.", "cdVmn3WggR8-00178-00076693-00077143": "We got lime salmon and we got a scarf boy. Okay.", "cdVmn3WggR8-00179-00077278-00077613": "1, 1, 2, 3, 4, arms salmon scarf. Boy,", "cdVmn3WggR8-00180-00077775-00077994": "let's go. All right. We're going to just scrape.", "cdVmn3WggR8-00181-00078365-00078662": "It's the worst timing I've ever had in my entire life on just about anything", "cdVmn3WggR8-00182-00078662-00079106": "I've ever done. Oopsies.", "cdVmn3WggR8-00183-00079453-00079876": "Star break. Anyway, that is waiver.", "cdVmn3WggR8-00184-00079876-00080247": "So I just want to talk briefly about it, general game thoughts, uh,", "cdVmn3WggR8-00185-00080247-00080530": "and then let you know, is it helpful if you want to improve your typing?", "cdVmn3WggR8-00186-00080557-00080737": "So as a general game, I think it's very cool.", "cdVmn3WggR8-00187-00080737-00081088": "I think arcade style is definitely the right way to explain it, I suppose.", "cdVmn3WggR8-00188-00081097-00081583": "And then, you know, there's a bigger story at hand here, but the idea,", "cdVmn3WggR8-00189-00081592-00082006": "I think I really like now totally overthinking what this game is trying to do.", "cdVmn3WggR8-00190-00082042-00082201": "The main idea I believe right,", "cdVmn3WggR8-00191-00082204-00082558": "is it's taking your keyboard and turning it into a unique controller. You know,", "cdVmn3WggR8-00192-00082558-00082783": "dance, dance revolution is up down left, right?", "cdVmn3WggR8-00193-00082783-00083152": "This is 26 different keys that you can use. So there's,", "cdVmn3WggR8-00194-00083157-00083371": "there's a whole lot going on in terms of, you know,", "cdVmn3WggR8-00195-00083416-00083629": "which key am I hitting in the first place?", "cdVmn3WggR8-00196-00083644-00083950": "And I guess that's why the first one's called typist when you don't, you know,", "cdVmn3WggR8-00197-00083950-00084394": "when you see the letters there that is for, you know, people like me typists,", "cdVmn3WggR8-00198-00084397-00084739": "but when you remove the letters, it adds an extra sense of challenge,", "cdVmn3WggR8-00199-00084742-00085054": "which segwaying into what I really want to talk about at the end here,", "cdVmn3WggR8-00200-00085066-00085315": "in terms of this video being on this channel, is,", "cdVmn3WggR8-00201-00085315-00085723": "does this improve your ability to type now I made a whole video about how typing", "cdVmn3WggR8-00202-00085723-00085912": "fast is kind of a useless skill. Uh,", "cdVmn3WggR8-00203-00085912-00086056": "you can check that out in the top right corner.", "cdVmn3WggR8-00204-00086098-00086449": "I actually think this would be kind of cool to experiment with first off,", "cdVmn3WggR8-00205-00086452-00086860": "those people with the scarves represent F and J these two keys on your keyboard,", "cdVmn3WggR8-00206-00086860-00087091": "have these little bumps on them, just the home row stuff.", "cdVmn3WggR8-00207-00087094-00087433": "But it's what I really like is that it challenges your finger positioning", "cdVmn3WggR8-00208-00087433-00087775": "because you have to a get her on the keyboard fast, you know,", "cdVmn3WggR8-00209-00087775-00088111": "on the typist mode, you can be okay, I have to hit Q even,", "cdVmn3WggR8-00210-00088112-00088447": "and then P or whatever, but this way it's, it's, you know,", "cdVmn3WggR8-00211-00088447-00088822": "I have to hit the key. That's three from the left on the top row, or, you know,", "cdVmn3WggR8-00212-00088822-00089103": "I have to get from the top left to the bottom, middle to the top, right again,", "cdVmn3WggR8-00213-00089126-00089579": "and do it in time. So as a, as an arcade style game, I really like it.", "cdVmn3WggR8-00214-00089585-00089825": "But also it's just a cool type of game. You know,", "cdVmn3WggR8-00215-00089825-00090131": "if you want to put on typist mode and learn how to touch type,", "cdVmn3WggR8-00216-00090137-00090401": "it seems like a cool resource and a more fun way to do things.", "cdVmn3WggR8-00217-00090401-00090641": "So as far as games like these go,", "cdVmn3WggR8-00218-00090686-00091100": "I really liked the visuals and the sound was great and fat goes a long way", "cdVmn3WggR8-00219-00091103-00091478": "because a lot of these types of games you can kind of find on the internet don't", "cdVmn3WggR8-00220-00091478-00091892": "have that. Um, so yeah, the game is on sale at 40% for the rest of the week.", "cdVmn3WggR8-00221-00091916-00092092": "I feel like I can do at least that for them, you know,", "cdVmn3WggR8-00222-00092093-00092348": "a hundred people maybe that watch this video. Anyway,", "cdVmn3WggR8-00223-00092351-00092435": "thanks so much for watching.", "cdVmn3WggR8-00224-00092435-00092720": "If you enjoy definitely the comment with your thoughts down below hit like", "cdVmn3WggR8-00225-00092720-00092990": "subscribe, all that fun stuff. Not at all. What I expected.", "cdVmn3WggR8-00226-00092993-00093377": "I expected to be typing words, but typing the characters and challenging my,", "cdVmn3WggR8-00227-00093380-00093617": "I guess, reflexes and spatial awareness. Anyway,", "cdVmn3WggR8-00228-00093620-00093863": "I'll definitely play more of this. If you want to watch me play more,", "cdVmn3WggR8-00229-00093863-00094091": "check the cat. Nork, I'll leave a link in the description.", "cdVmn3WggR8-00230-00094115-00094262": "I never really thought to plug that channel.", "cdVmn3WggR8-00231-00094265-00094490": "Never really intended to probably won't in the future,", "cdVmn3WggR8-00232-00094493-00094814": "but I definitely see myself playing more of this game because someone brought up", "cdVmn3WggR8-00233-00094814-00095183": "recently that spatial awareness is potentially irrelevant or a correlated skill", "cdVmn3WggR8-00234-00095183-00095231": "and typing.", "cdVmn3WggR8-00235-00095231-00095549": "And this really does challenge that because the keys don't have letters anymore.", "cdVmn3WggR8-00236-00095552-00095918": "It's more so about their relative spacing to each other.", "cdVmn3WggR8-00237-00095930-00096206": "Thank you for watching this video. If you are curious about more typing content,", "cdVmn3WggR8-00238-00096215-00096326": "that's on screen. Now,", "cdVmn3WggR8-00239-00096350-00096707": "some of my dev logs are also on screen now for anyone who followed those,", "cdVmn3WggR8-00240-00096710-00097040": "there'll be returning this semester. I'm making seashell a very big project. Oh,", "cdVmn3WggR8-00241-00097042-00097217": "thanks again to waver for sending me a steam key,", "cdVmn3WggR8-00242-00097217-00097565": "but more so thanks to you for watching. So have a good one and as always,", "cdVmn3WggR8-00243-00097565-00097883": "don't forget to stay awesome. See you next week."}}, {"audio_id": "cdb0yW6DsLE", "text": {"cdb0yW6DsLE-00000-00000440-00000960": "So hi I'm Margaret Gam. I'm director of Special Collections and Archives at the University of", "cdb0yW6DsLE-00001-00000960-00001496": "Iowa Libraries and I'd like to thank you for joining us today. I would also like to acknowledge", "cdb0yW6DsLE-00002-00001496-00002072": "that the University of Iowa is located on the historical homelands of over 15 tribal nations.", "cdb0yW6DsLE-00003-00002072-00002600": "The Omaha tribe of Nebraska and Iowa, the Ponca tribe of Nebraska, the Meskwaki and Ho-Chunk", "cdb0yW6DsLE-00004-00002600-00003056": "nations continue to thrive in the state of Iowa, and we continue to acknowledge them.", "cdb0yW6DsLE-00005-00003120-00003544": "To help you start your own exploration of these histories of Iowa and its people, we encourage", "cdb0yW6DsLE-00006-00003544-00004032": "you to take a look at the links provided in the Zoom chat or in the YouTube video description.", "cdb0yW6DsLE-00007-00004232-00004848": "So today we will hear from Emily Martin, adjunct assistant professor in book binding and book arts", "cdb0yW6DsLE-00008-00004848-00005360": "at the University of Iowa Center for the Book. Here in Special Collections and Archives we are", "cdb0yW6DsLE-00009-00005360-00005816": "thrilled to have well over a hundred works created by Emily, as well as her papers going back to", "cdb0yW6DsLE-00010-00005816-00006464": "the start of her career. Emily last spoke at a bibliophiles event in 2016 about her creations", "cdb0yW6DsLE-00011-00006464-00007000": "interpreting themes in Shakespeare. This continues to be a theme in her work with a particular focus", "cdb0yW6DsLE-00012-00007000-00007616": "on women in Shakespeare. This time Emily, who is an active member of the Movable Book Society,", "cdb0yW6DsLE-00013-00007616-00008608": "joins us to talk about movable books. Emily, over to you. All right thank you. I want to start off", "cdb0yW6DsLE-00014-00008608-00009464": "by thanking Elizabeth Reardon for inviting me to do this presentation, and I'd also like to thank", "cdb0yW6DsLE-00015-00009464-00010120": "Eric Ensley, Curator of Rare Books and Maps in Special Collections, and Damian Eric, who's the", "cdb0yW6DsLE-00016-00010120-00010640": "curator at the John Martin Rare Book Room over in the Hardin Library for the Health Sciences. They", "cdb0yW6DsLE-00017-00010640-00011320": "were both really invaluable for my presentation today. Most of the books that I'm going to show", "cdb0yW6DsLE-00018-00011320-00012240": "you are in those libraries, so if you are local you can go and see them in person there. And so", "cdb0yW6DsLE-00019-00012392-00013104": "because we are not live, I'm gonna do it as a Powerpoint, so I'm gonna share my screen.", "cdb0yW6DsLE-00020-00013232-00014208": "Okay, so here we are. And as the title says, pop-ups and movables especially are much", "cdb0yW6DsLE-00021-00014208-00014904": "older than people think, and see, most people are familiar with the sort of modern,", "cdb0yW6DsLE-00022-00014904-00015391": "spectacular pop-ups books that are aimed primarily at children, although many of them", "cdb0yW6DsLE-00023-00015391-00015936": "appeal to all ages. And those types of books are relatively new in the history of pop-ups", "cdb0yW6DsLE-00024-00015936-00016728": "and movable books. So I'm going to start off by defining my terms here. When I refer to movables,", "cdb0yW6DsLE-00025-00016728-00017312": "I'm talking about the parts of books that are moved by the viewer, and pop-ups are the parts", "cdb0yW6DsLE-00026-00017312-00017912": "of books that are moved by the book itself. By that I mean opening a book or turning a page.", "cdb0yW6DsLE-00027-00017992-00018584": "And indeed in all sense, all books are movable, but I'm going to talk about books where there", "cdb0yW6DsLE-00028-00018584-00019280": "is movement other than the standard paging through that happens in common book forms.", "cdb0yW6DsLE-00029-00019584-00020360": "I am a member of the Movable Book Society which is an international organization of collectors,", "cdb0yW6DsLE-00030-00020360-00020824": "historians, book dealers, paper engineers, artists, and enthusiasts.", "cdb0yW6DsLE-00031-00020960-00021664": "This organization was founded by Anne Montanaro Staples in 1993, and the Moveable Book Society", "cdb0yW6DsLE-00032-00021664-00022248": "published a book commemorating the 10th anniversary of that founding in 2014.", "cdb0yW6DsLE-00033-00022344-00022952": "The book cover has a hidden device, which when open, reveals a facsimile honoring the", "cdb0yW6DsLE-00034-00022952-00023392": "inventor of the first known movables, which is Matthew Paris.", "cdb0yW6DsLE-00035-00023704-00024352": "Books with movable parts were made as early as the 13th century. This English monk, Matthew Paris,", "cdb0yW6DsLE-00036-00024352-00025136": "who was born in 1200 and died in 1259, lived in the Saint Albans Abbey in Hertfordshire England,", "cdb0yW6DsLE-00037-00025136-00025760": "and is credited with being the first maker of both the fold-out flap and the volvelle, or turning", "cdb0yW6DsLE-00038-00025760-00026432": "wheel. This commemorative device was designed by Robert Cebuda, a well-known contemporary paper", "cdb0yW6DsLE-00039-00026432-00027072": "engineer. Many of you might be familiar with his books. And here Robert presents a facsimile", "cdb0yW6DsLE-00040-00027127-00028183": "volvelle, and uses a lift flap to activate the pop-ups of the self-portrait of Matthew Paris.", "cdb0yW6DsLE-00041-00028895-00029408": "Paris was the abbey's historian, and he embarked on an illustrated story", "cdb0yW6DsLE-00042-00029408-00029960": "of humankind from creation to his present day, Chronica Majora: a three-volume work.", "cdb0yW6DsLE-00043-00030080-00030592": "Two volumes are held in the Corpus Christi College Libraries in Cambridge and the third is in the", "cdb0yW6DsLE-00044-00030592-00031383": "British Library. Paris is credited with inventing the first known movable the wheel, the volvelle,", "cdb0yW6DsLE-00045-00031383-00032200": "from the Latin verb \"volvair,\" meaning to turn or roll around. Prior to the invention, monks would", "cdb0yW6DsLE-00046-00032200-00032880": "have to rotate heavy books that contain circular charts made up of columns when calculating Easter", "cdb0yW6DsLE-00047-00032880-00033456": "and other holy days. The volvelle allowed the monks to rotate only the circular chart,", "cdb0yW6DsLE-00048-00033456-00034016": "not the entire cumbersome book. I'll return to volvelles at the end of my presentation.", "cdb0yW6DsLE-00049-00034240-00035056": "For those of you who want to get more into the history of, that I will mention...here, this is my", "cdb0yW6DsLE-00050-00035056-00035536": "favorite book on early movables. It's \"Interactive and Sculptural Printmaking in the Renaissance\"", "cdb0yW6DsLE-00051-00035536-00036272": "from Suzanne Karr Schmidt, and it's published by Brill Studies and Intellectual History in 2018.", "cdb0yW6DsLE-00052-00036272-00037192": "I believe it will soon be in the collections of the Special Collections. It's from Suzanne's book,", "cdb0yW6DsLE-00053-00037192-00037808": "that I borrowed this illustration of a map of the itinerary from London to Jerusalem for the", "cdb0yW6DsLE-00054-00037808-00038776": "Historia Anglorum, circa 1250-1259 held in the British Library. This shows Matthew Paris's second", "cdb0yW6DsLE-00055-00038776-00039416": "movable invention, the lift flap or the foldout map. I'm in a quote from Suzanne's book here,", "cdb0yW6DsLE-00056-00039488-00039960": "\"The monk imitated the map's movements as he worked its pages and flaps, and the", "cdb0yW6DsLE-00057-00039960-00040632": "multi-sensorial experience of that working and the places it described, constructed a performative", "cdb0yW6DsLE-00058-00040632-00041160": "setting in which the monk could realize an imagined pilgrimage to the holy Jerusalem.", "cdb0yW6DsLE-00059-00041248-00041784": "And this sensorial experience is a major component of the viewing of books containing", "cdb0yW6DsLE-00060-00041784-00042400": "pop-ups and movables. It's more than a simple reading experience. The viewer is interacting", "cdb0yW6DsLE-00061-00042400-00042888": "with the book, it's an involvement beyond reading.\" Lift flaps and volvelles are also", "cdb0yW6DsLE-00062-00042888-00043400": "extremely versatile devices as you'll see from the assortment of examples that I'll be showing this", "cdb0yW6DsLE-00063-00043400-00044368": "evening. And not all lift flaps are complicated. I'll now show you a couple of newish, ephemera", "cdb0yW6DsLE-00064-00044368-00045016": "pieces. This first one is from the Bodleian Bibliographical Press, where I spent a very happy", "cdb0yW6DsLE-00065-00045176-00045880": "month in the fall of 2018. And this is printed from old wood blocks to make this pair of figures.", "cdb0yW6DsLE-00066-00046216-00046384": "The second one I'm going to show you", "cdb0yW6DsLE-00067-00046792-00047616": "is a reprint of an advertisement from the Library Company in Philadelphia. This is a very simple,", "cdb0yW6DsLE-00068-00047680-00048464": "single flap, but it allows the entire scene to be altered. This is an advertisement for coconut.", "cdb0yW6DsLE-00069-00048904-00049576": "We're going to move forward to the 16th century. Here we see D Humanity Corporis Fabrica", "cdb0yW6DsLE-00070-00049576-00050512": "Laborum Epitome, from 1543. One of the most influential books on human anatomy by Andreas", "cdb0yW6DsLE-00071-00050512-00051320": "Vesalius. He was born in Brussels in 1541, which was then a part of the Hopsburgs, Netherlands. He", "cdb0yW6DsLE-00072-00051320-00052104": "died in 1564 in what is now a part of Greece. And Vesalius was the 16th century anatomist,", "cdb0yW6DsLE-00073-00052104-00052760": "physician, and author, He's often referred to as a founder of human, modern human anatomy.", "cdb0yW6DsLE-00074-00052848-00053391": "He revolutionized the study of biology and the practice of medicine by his careful description", "cdb0yW6DsLE-00075-00053391-00054040": "of the anatomy of the human body. He based his descriptions on dissections he made himself,", "cdb0yW6DsLE-00076-00054112-00054544": "and then wrote and illustrated this first comprehensive textbook of anatomy.", "cdb0yW6DsLE-00077-00054608-00055344": "This book has anatomical elements that can be cut out, such as the liver here,", "cdb0yW6DsLE-00078-00055344-00056184": "and layered to replicate human anatomy. This book was intended for teaching purposes.", "cdb0yW6DsLE-00079-00056344-00056920": "This next book is from the 17th century, and it's Catopter Microcosmicum.", "cdb0yW6DsLE-00080-00057024-00057824": "Printed in Augsburg in 1619 by Johann Remmelin, with illustrations by Lucas Lillen. Remmelin", "cdb0yW6DsLE-00081-00057888-00058976": "designed male and female paper figures using a series of overlapping flaps. This book,", "cdb0yW6DsLE-00082-00058976-00059608": "in the overlapping flaps were to illustrate the successive layers of the human body. This book", "cdb0yW6DsLE-00083-00059608-00060424": "was intended more for the curious lay person rather than a medical student or a physician.", "cdb0yW6DsLE-00084-00060488-00061072": "Remmelin's work was a popular science bestseller of its day, and it was reprinted numerous times.", "cdb0yW6DsLE-00085-00061616-00061967": "These are little modesty flaps that were included,", "cdb0yW6DsLE-00086-00061967-00062479": "and you'll see anatomical lift flaps in contemporary trade editions,", "cdb0yW6DsLE-00087-00062479-00062936": "and also in artists books, such as these next books that I'm going to show you.", "cdb0yW6DsLE-00088-00063088-00063736": "So contemporary artists have been making use of anatomical lift flaps in a variety of ways. \"Body", "cdb0yW6DsLE-00089-00063736-00064360": "of Inquiry,\" a triptych opening to a corporeal codex by Casey Gardner from Seton Motion Press", "cdb0yW6DsLE-00090-00064360-00065232": "was printed in 2011. As you can see this is a triptych. It's a letterpress printed, but holding", "cdb0yW6DsLE-00091-00065232-00065976": "a sewn codex within the subject's torso. And so as you open the three flaps of the triptych,", "cdb0yW6DsLE-00092-00065976-00066696": "you get to this interior codex. I'm going to take you through some of the the layers of this.", "cdb0yW6DsLE-00093-00066976-00067664": "This interior codex held in the torso of a printed female anatomical model, unfolds", "cdb0yW6DsLE-00094-00067664-00068200": "the story of the scientific journey that an actual, anatomical model inspired for this work.", "cdb0yW6DsLE-00095-00068312-00069016": "Casey Gardner was inspired from the enigma posed by the models enviable composure,", "cdb0yW6DsLE-00096-00069016-00069736": "despite her utter, available viscera, available and exposed viscera. For years Casey referred", "cdb0yW6DsLE-00097-00069736-00070528": "to her as \"Our lady of serene evisceration,\" and marveled at her inner workings. And you go through", "cdb0yW6DsLE-00098-00070528-00071584": "the various layers with the text involved, and so this is a little video of one of the elements.", "cdb0yW6DsLE-00099-00072400-00072856": "This is the back of the book. It kind of references the volvelle with the circular", "cdb0yW6DsLE-00100-00072856-00073400": "presentation of the various possibilities, such as \"hoping with the eye of an egress,\"", "cdb0yW6DsLE-00101-00073400-00073848": "or \"believing as a pop quiz,\" but this particular circle does not move.", "cdb0yW6DsLE-00102-00074072-00074896": "The next book I'm going to discuss is \"Anatomia Botanica,\" by Radha Pandey. This was printed in", "cdb0yW6DsLE-00103-00074896-00075576": "Iowa City, and this book invites the viewer to experience three species of flowering plants", "cdb0yW6DsLE-00104-00075576-00076152": "that shape the artist's understanding of her natural environment. I'm going to show you the", "cdb0yW6DsLE-00105-00076152-00077224": "southern magnolia first. And this, as you can see, has lift flaps to show the anatomy of the plant.", "cdb0yW6DsLE-00106-00077224-00077992": "The second one is the red hibiscus, and Radha drew her inspiration from the illustrative", "cdb0yW6DsLE-00107-00077992-00078904": "styles of these images from 16th to 18th century European and American botanicals and the mobile", "cdb0yW6DsLE-00108-00079216-00079744": "architectural motifs. And you can see how the movable aspect and mechanisms used", "cdb0yW6DsLE-00109-00079744-00080304": "for these illustrations also reference the 16th century anatomical flap books,", "cdb0yW6DsLE-00110-00080304-00081000": "and they function in a similar fashion. Radha is an alumni of the University of Iowa's Center for", "cdb0yW6DsLE-00111-00081000-00081520": "the Books MFA Program in Book Arts, and her studies for this book were done here at the", "cdb0yW6DsLE-00112-00081520-00082176": "University of Iowa Libraries. This book has been letterpress printed using reduction linoleum cuts,", "cdb0yW6DsLE-00113-00082176-00082784": "handset metal type with push bar and photopolymer plates on handmade paper.", "cdb0yW6DsLE-00114-00082960-00083488": "Very briefly we're going to return to the 16th century for this book,", "cdb0yW6DsLE-00115-00083600-00084376": "\"Ophthalmodouleia\" I believe, Dresden 1583 from Georg Bartisch. And this is the first", "cdb0yW6DsLE-00116-00084376-00084944": "systematic work on eye diseases, and is also notable for being printed in the vernacular", "cdb0yW6DsLE-00117-00085040-00085704": "rather than the Latin or Greek. This is also from the Martin Rare Book Room", "cdb0yW6DsLE-00118-00085704-00086160": "in the Hardin Library. And this is another view of the different layers.", "cdb0yW6DsLE-00119-00086520-00087008": "That brings us to this book, which is a collaborative book between Julie Chen and", "cdb0yW6DsLE-00120-00087008-00087904": "Clifton Meador, who are contemporary artists. It has a bit of a nod to the eye of the eye", "cdb0yW6DsLE-00121-00087904-00088624": "anatomy we just saw. This is called \"How Books Work,\" printed in 2010. And this contemporary", "cdb0yW6DsLE-00122-00088624-00089232": "book presents the layers of book definitions in a series of lift flaps in all four directions.", "cdb0yW6DsLE-00123-00089232-00089768": "The lift flaps engage the viewer in peeling back those layers of meaning, somewhat like", "cdb0yW6DsLE-00124-00089768-00090384": "you would go through the anatomy of the eye. You read this book while the book looks back to you,", "cdb0yW6DsLE-00125-00090456-00090872": "back at you meeting your gaze. So I'm going to take you through the flaps.", "cdb0yW6DsLE-00126-00090992-00091616": "\"What is the book?\" \"A book is an experience. Reading creates an intimate space.\"", "cdb0yW6DsLE-00127-00091800-00092328": "\"A book contains time.\" \"The book is a vehicle for meaning.\"", "cdb0yW6DsLE-00128-00092568-00092840": "\"The reader brings the book into existence.\"", "cdb0yW6DsLE-00129-00093112-00093520": "\"The power of a book is based on your willingness to surrender your prejudices", "cdb0yW6DsLE-00130-00093520-00094232": "and beliefs for the duration of your interaction with it.\" \"But the book doesn't really speak,", "cdb0yW6DsLE-00131-00094232-00094896": "your own mind is doing all the talking.\" \"A book starts with an idea, but it ends with the reader.\"", "cdb0yW6DsLE-00132-00095184-00095824": "I'm gonna move on to the next book, which is also by an alumni, alumna of the", "cdb0yW6DsLE-00133-00095880-00096352": "Center for the Book. This is Elizabeth Munger's book, \"The Story of the Table Setting.\"", "cdb0yW6DsLE-00134-00096432-00097168": "And this book uses very simple fold out pages. The foldouts allow her to expand her storytelling", "cdb0yW6DsLE-00135-00097168-00097816": "and keep the viewer engaged as she animates the silverware of a proper place setting with the", "cdb0yW6DsLE-00136-00097816-00098384": "story that she learned from her mother and grandmother. I offer this brief synopsis:", "cdb0yW6DsLE-00137-00098584-00098944": "\"In the kingdom of the placemat, where there is a castle, the plate.", "cdb0yW6DsLE-00138-00099080-00099840": "The evil knight fork, and his son, salad fork are from the far off country of left. The forks", "cdb0yW6DsLE-00139-00099840-00100512": "and their army invade the kingdom, setting up their tent, the napkin. They want to steal", "cdb0yW6DsLE-00140-00100512-00101192": "princess spoon as a bride for the salad fork. The king enlists the aid of the very tall knight,", "cdb0yW6DsLE-00141-00101256-00101928": "sir knife, to battle the evil forks. After a great battle, the salad and the salad fork's army", "cdb0yW6DsLE-00142-00101928-00102656": "is destroyed, and only they remain. Princess spoon and sir knight have also fallen in love. A crystal", "cdb0yW6DsLE-00143-00102656-00103400": "palace is built right by the castle for the happy couple. To this day, whenever you visit the table,", "cdb0yW6DsLE-00144-00103400-00104072": "you will find sir knife, the right, below the crystal tower protecting princess spoon. The", "cdb0yW6DsLE-00145-00104072-00104664": "thwarted fork and salad fork are left with their napkin tent on the other side of the castle.\"", "cdb0yW6DsLE-00146-00104880-00105280": "And with that, we return to the first volvelle of Matthew Paris.", "cdb0yW6DsLE-00147-00105448-00106080": "This next device is also from Suzanne Karr Schmitz. This is a decoding volvelle,", "cdb0yW6DsLE-00148-00106168-00106800": "which has a movable dial in the center which allows you to decipher an encrypted message.", "cdb0yW6DsLE-00149-00106992-00107672": "This is a an example of an uncut, woodcut volvelle in dials, which are not uncommon to be found", "cdb0yW6DsLE-00150-00107672-00108256": "where they were meant to be cut up and assembled, but for whatever reason, they remain on their", "cdb0yW6DsLE-00151-00108335-00109383": "base sheet. And so in Suzanne's book she includes it as a you can make your own facsimile.", "cdb0yW6DsLE-00152-00109448-00110232": "Eric Ensley at the University has recently introduced me to this uncut scientific device", "cdb0yW6DsLE-00153-00110288-00110920": "for studying astronomy, and it's found in this book, which is \"A brief and most easy introduction", "cdb0yW6DsLE-00154-00110920-00111624": "to the Astrological Judgment of the Stars,\" written in London in 1598. And it was written", "cdb0yW6DsLE-00155-00111624-00112224": "in the English vernacular of the time, and I'm really looking forward to spending more time with", "cdb0yW6DsLE-00156-00112224-00113072": "this book, and making copies and constructing my own facsimile for this astronomical device.", "cdb0yW6DsLE-00157-00113176-00113856": "And now we're going to move on to some contemporary uses of the volvelle device.", "cdb0yW6DsLE-00158-00113920-00114824": "This is \"Subject, Verb, Object,\" from Ellen Newton of Crooked Letter Press, 2012. And I'm", "cdb0yW6DsLE-00159-00114824-00115488": "going to paraphrase from Ellen's website, \"Ellen developed this particular volvelle as a word game", "cdb0yW6DsLE-00160-00115680-00116264": "that grew from a need to process feelings of anger. The game has no beginning, no end,", "cdb0yW6DsLE-00161-00116264-00116959": "and no way to win. The turning, fitting, and order of the words can lead to clarity or confusion.\"", "cdb0yW6DsLE-00162-00117424-00117959": "\"The reader plays with the language and considers some of the options about what we want, need,", "cdb0yW6DsLE-00163-00117959-00118544": "and have. The concept behind the book stems from her frustration and anger that she felt towards", "cdb0yW6DsLE-00164-00118544-00119200": "art criticism and other academic writing. Academic language seemed intended to control its audience,", "cdb0yW6DsLE-00165-00119200-00119640": "to exclude outsiders, and is not meant to clarify the subject for a reader.", "cdb0yW6DsLE-00166-00119711-00120096": "It takes the beauty and passion out of language, and in turn, out of people.", "cdb0yW6DsLE-00167-00120200-00120800": "Ellen's volvelle pokes at this idea by doing something similar. It uses simplistic language", "cdb0yW6DsLE-00168-00120928-00121400": "and structure to force the reader to attempt a visual organization of the things we cannot", "cdb0yW6DsLE-00169-00121400-00121983": "put in order, our desires.\" And this is also letterpress printed.", "cdb0yW6DsLE-00170-00122152-00122568": "Coincidentally, this second volvelle also pokes at the use of jargon.", "cdb0yW6DsLE-00171-00122568-00123400": "This is Dan Mayer's \"MayBow's Jargonator\" from election 2000 Wonk Wheel from 2001.", "cdb0yW6DsLE-00172-00123400-00123840": "It lets us all play spin doctor with the language from the 2000 election.", "cdb0yW6DsLE-00173-00123840-00124424": "And for those of you who have forgotten, that was the the time of the hanging chad.", "cdb0yW6DsLE-00174-00124704-00125344": "And so the three wheels allow you to construct any number of phrases,", "cdb0yW6DsLE-00175-00125424-00126183": "critical or humorous, or snarky, however you care to interpret that.", "cdb0yW6DsLE-00176-00126696-00127448": "I myself have made use of the volvelle forms somewhat recently. I used them for my", "cdb0yW6DsLE-00177-00127448-00128064": "Oscar Wilde book, which was printed in 2020. I made two sided volvelles,", "cdb0yW6DsLE-00178-00128135-00128696": "where the playwright Oscar Wilde trades lines with his characters from \"The Importance of", "cdb0yW6DsLE-00179-00128696-00129256": "Being Earnest.\" And Wilde often voiced his own opinions through the mouths of his characters,", "cdb0yW6DsLE-00180-00129256-00130383": "so it seemed appropriate to use the volvelle form. And so I'm gonna show you this video of the book.", "cdb0yW6DsLE-00181-00130616-00131168": "\"Oscar Wilde: In Earnest and Out,\" is an artist book by me, Emily Martin.", "cdb0yW6DsLE-00182-00131240-00131864": "And I became aware of Oscar Wilde's plays in college when I took a class where we studied them.", "cdb0yW6DsLE-00183-00131920-00132624": "He was celebrated during his time in the late 1800s as a writer of all sorts, and in particular", "cdb0yW6DsLE-00184-00132624-00133184": "as a playwright. He was at the height of a celebrity when he was accused of being a sodomite.", "cdb0yW6DsLE-00185-00133312-00133888": "Sued, and not only lost the suit, but was then convicted of committing acts of", "cdb0yW6DsLE-00186-00133888-00134616": "gross indecency with other male persons under section 11 of the 1885 criminal law amendment", "cdb0yW6DsLE-00187-00134616-00135136": "act. And this act was not fully repealed in England until 2003.", "cdb0yW6DsLE-00188-00135512-00136240": "\"The Importance of Being Earnest\" was one of his most famous plays. It's a social commentary and", "cdb0yW6DsLE-00189-00136240-00136984": "very witty, and it has a number of characters who trade lines with each other throughout the play.", "cdb0yW6DsLE-00190-00137200-00137488": "And this artist book is a series of volvelles", "cdb0yW6DsLE-00191-00137560-00138360": "in which Oscar and five of the characters from his play have a dialogue of sorts, using", "cdb0yW6DsLE-00192-00138360-00138856": "lines from the play, and then Oscar's lines are all from other of his writing.", "cdb0yW6DsLE-00193-00139432-00139488": "Algernon:", "cdb0yW6DsLE-00194-00139920-00140376": "\"The truth is rarely pure and never simple.\"", "cdb0yW6DsLE-00195-00140656-00141800": "Oscar: \"The public have an insatiable curiosity to know everything except what is worth knowing.\"", "cdb0yW6DsLE-00196-00142728-00143440": "Lady Bracknell: \"To lose one parent may be regarded", "cdb0yW6DsLE-00197-00143496-00144400": "as a misfortune. To lose both seems like carelessness.\"", "cdb0yW6DsLE-00198-00144400-00145184": "Then Oscar: \"Morality is simply the attitude we adopt towards people we personally dislike.\"", "cdb0yW6DsLE-00199-00145768-00147216": "Miss Prism: \"The good and happily and the bad, unhappily, that is what fiction means.\"", "cdb0yW6DsLE-00200-00147216-00147840": "Oscar: \"Experience is the name everyone gives to their mistakes.\"", "cdb0yW6DsLE-00201-00148472-00149560": "Jack: \"It is a terrible thing for a man to find out suddenly that all his life", "cdb0yW6DsLE-00202-00149632-00149984": "he has been speaking nothing but the truth.\"", "cdb0yW6DsLE-00203-00150256-00150920": "and Oscar: \"Most people are other people. Their thoughts", "cdb0yW6DsLE-00204-00150920-00151656": "are someone else's opinion. Their lives, a mimicry. Their passions, a quotation.\"", "cdb0yW6DsLE-00205-00152520-00153640": "Gwendolyn: \"In matters of grave importance, style, not sincerity, is the vital thing.\"", "cdb0yW6DsLE-00206-00153880-00154384": "And Oscar: \"To get into the best society nowadays,", "cdb0yW6DsLE-00207-00154448-00155584": "one has either to feed people, amuse people, or shock people. That is all.\"", "cdb0yW6DsLE-00208-00156344-00156792": "Okay and thank you."}}, {"audio_id": "ce1swVnTC3M", "text": {"ce1swVnTC3M-00000-00000321-00000967": "Hello everybody welcome to this video we are here in a sequence of questions which were there", "ce1swVnTC3M-00001-00000967-00001620": "in the previous year UGC NET exam so here is a simple problem which is based on linear", "ce1swVnTC3M-00002-00001620-00002002": "transformations look at the statement of the problem the statement says which of the following", "ce1swVnTC3M-00003-00002002-00002459": "is a linear transformation so you given some linear transformations and you have to find", "ce1swVnTC3M-00004-00002459-00003207": "out which one is area you are given some transformations and you have to find out which one is a linear", "ce1swVnTC3M-00005-00003207-00003668": "transformation to let us look at the first example you have a transformation which takes", "ce1swVnTC3M-00006-00003668-00004939": "xyz to 4 plus x y x 4 x + 5 so you can see that your transformation is from 32 to write", "ce1swVnTC3M-00007-00004939-00005689": "their calling it a f g and h it is either F for ki or se and you have to verify or your", "ce1swVnTC3M-00008-00005689-00006561": "to find out which one is a linear transformation let's look at the option A you have f x y", "ce1swVnTC3M-00009-00006561-00007381": "z is given as 4 x + Y and you know that for a transformation to be a linear transformation", "ce1swVnTC3M-00010-00007381-00008246": "you should have if we take X capital x is equal to X1 Y1 Z1 and capital by as X2 Y2", "ce1swVnTC3M-00011-00008246-00009256": "Z2 then you should have a far-off Alfa X Plus Bita by as Alpha f of X + guitar type of world", "ce1swVnTC3M-00012-00009256-00009997": "this is required for the transmission to be linear transformation this is your requirement", "ce1swVnTC3M-00013-00009997-00010806": "fine now let's look here to you have therefore of Alfa X + beta why is going to be a part", "ce1swVnTC3M-00014-00010806-00012629": "of Alpha X1 plus beta X2 Alpha Y1 plus Bita Y2 Alpha Z1 Plus beta Z2 Fine love u i will", "ce1swVnTC3M-00015-00012629-00013709": "get food coma you will get X + 5 that is alpha X1 plus Bita X2 + alpha by 1 + beta white", "ce1swVnTC3M-00016-00013709-00014502": "to this is your F of alpha + beta by life you look at Alpha f of X + beta f off while", "ce1swVnTC3M-00017-00014502-00015369": "but you are going to get you going to get alpha that will be 4x oneplus 5 plus Bita", "ce1swVnTC3M-00018-00015369-00016490": "4x X2 + Y2 now you add it will get for alpha plus 4 beta Alpha X1 plus Bita X2 + alpha", "ce1swVnTC3M-00019-00016490-00017723": "by 1 + beta Y2 now you look at the to this one here and this one here they are not equal", "ce1swVnTC3M-00020-00017723-00018443": "right they are not equal because of the first component is not equal therefore Alfa El jefe", "ce1swVnTC3M-00021-00018443-00019523": "Alfa X + beta why is not equal to Alpha f of X + beta f of why it implies f is not a", "ce1swVnTC3M-00022-00019523-00020842": "linear transformation f is not a linear transformation at option 20 option is option is not correct", "ce1swVnTC3M-00023-00020842-00021401": "fine now you see similarly option B you can just look at the option also you can find", "ce1swVnTC3M-00024-00021401-00021858": "out here you see the term is there xy and you know that for Linear there cannot be a", "ce1swVnTC3M-00025-00021858-00022347": "product of your time that's why so this is also not be in your but you can verify of", "ce1swVnTC3M-00026-00022347-00022995": "cost and here you can verify that it was clear that is true that the path path and sorry", "ce1swVnTC3M-00027-00022995-00024220": "Si part your age of XYZ is Z - x x + Y I am taking again here let me that only since there", "ce1swVnTC3M-00028-00024220-00025620": "is a term xy on the right inside there for Non linear path to see you have xyz assets", "ce1swVnTC3M-00029-00025620-00026452": "minus 6 X + Y if you take Alfa X + beta why where x and y are same as in the path to this", "ce1swVnTC3M-00030-00026452-00027708": "is a choice of pulse X 1 + beta X2 alpha by 1 + beta By Two Alpha Z1 Plus Bita Z2 so this", "ce1swVnTC3M-00031-00027708-00028478": "is that component that that is alpha Z1 Plus Bita Z 2 - X component myself at one minus", "ce1swVnTC3M-00032-00028478-00029288": "b tax to form a first component that is alpha H1 plus Bita X2 + the second component + Alpha", "ce1swVnTC3M-00033-00029288-00030081": "11 plus Bita by two for the right it as you can see it as Alpha you take this Alpha Alpha", "ce1swVnTC3M-00034-00030081-00030958": "Alpha Alpha terms that will be Alpha Z1 - 1 X 1 + 1 and now you take beta beta beta beta", "ce1swVnTC3M-00035-00030958-00031913": "terms you will have beta you will have set 2 - X2 X2 + Y2 so this is this is a chart", "ce1swVnTC3M-00036-00031913-00033013": "of X + beta this is a choice of why you get off alpha + beta as alpha-h of X + beta ho5", "ce1swVnTC3M-00037-00033013-00033690": "it implies that is a linear transformation process option d is also that is also so called", "ce1swVnTC3M-00038-00033690-00034258": "because A and B are not linear transformation function is called b is called she is correct", "ce1swVnTC3M-00039-00034258-00034840": "the is called to see is the correct option for this problem and discussion was there", "ce1swVnTC3M-00040-00034840-00035602": "in June 2015 and it was it was of 3 marks thank you for watching this video please subscribe", "ce1swVnTC3M-00041-00035602-00035761": "to this channel and share this video with your friends"}}, {"audio_id": "ceCQ9BC2jjU", "text": {"ceCQ9BC2jjU-00000-00000554-00000904": "(upbeat electronic music)", "ceCQ9BC2jjU-00001-00002066-00002160": ">> Hey, welcome back everybody.", "ceCQ9BC2jjU-00002-00002160-00002267": "Jeff Frick here with theCUBE.", "ceCQ9BC2jjU-00003-00002267-00002531": "We are live in downtown San Francisco, Moscone Center", "ceCQ9BC2jjU-00004-00002531-00002633": "at the RSA conference.", "ceCQ9BC2jjU-00005-00002633-00002771": "It's one of the biggest conferences,", "ceCQ9BC2jjU-00006-00002771-00002964": "I think after like Salesforce and Oracle", "ceCQ9BC2jjU-00007-00002964-00003164": "that they have in Moscone on the tech scene.", "ceCQ9BC2jjU-00008-00003164-00003496": "Over 40,000 professionals here talking about security,", "ceCQ9BC2jjU-00009-00003496-00003672": "I think it was 34,000 last year.", "ceCQ9BC2jjU-00010-00003672-00003906": "It's so busy they can't find a space for theCUBE,", "ceCQ9BC2jjU-00011-00003906-00004059": "so we just have to make our way in.", "ceCQ9BC2jjU-00012-00004059-00004243": "We're really excited by our next guest,", "ceCQ9BC2jjU-00013-00004243-00004527": "Ted Julian from IBM Resistance,", "ceCQ9BC2jjU-00014-00004527-00004650": "Resilience, excuse me.", "ceCQ9BC2jjU-00015-00004650-00004740": ">> Thank you, it's alright.", "ceCQ9BC2jjU-00016-00004740-00004859": ">> And you are the co-founder of VP Product Management.", "ceCQ9BC2jjU-00017-00004859-00004942": ">> That's right.", "ceCQ9BC2jjU-00018-00004942-00005025": ">> Welcome.", "ceCQ9BC2jjU-00019-00005025-00005122": ">> Thanks, good to be here Jeff, thanks.", "ceCQ9BC2jjU-00020-00005122-00005382": ">> And you said IBM actually purchased a company,", "ceCQ9BC2jjU-00021-00005382-00005466": ">> Ted: A year ago.", "ceCQ9BC2jjU-00022-00005466-00005549": ">> A year ago. So happy anniversary.", "ceCQ9BC2jjU-00023-00005549-00005655": ">> Ted: Yeah, thanks.", "ceCQ9BC2jjU-00024-00005655-00005739": ">> So how is that going?", "ceCQ9BC2jjU-00025-00005739-00005836": ">> It's great.", "ceCQ9BC2jjU-00026-00005836-00005994": "Business is really going well,", "ceCQ9BC2jjU-00027-00005994-00006195": "it's been thrilling to get our product in place", "ceCQ9BC2jjU-00028-00006195-00006301": "and a lot more customers", "ceCQ9BC2jjU-00029-00006301-00006502": "and really see it help make a difference for them.", "ceCQ9BC2jjU-00030-00006502-00006585": ">> Yeah we,", "ceCQ9BC2jjU-00031-00006585-00006784": "Jesse Proudman is a many time CUBE alumni,", "ceCQ9BC2jjU-00032-00006784-00006881": "his company is Blue Box,", "ceCQ9BC2jjU-00033-00006881-00006985": "also bought by IBM.", "ceCQ9BC2jjU-00034-00006985-00007068": ">> Ted: Yes.", "ceCQ9BC2jjU-00035-00007068-00007152": ">> A little while ago,", "ceCQ9BC2jjU-00036-00007152-00007314": "also had a really good experience of,", "ceCQ9BC2jjU-00037-00007314-00007453": "kind of bringing all that horse power.", "ceCQ9BC2jjU-00038-00007453-00007542": ">> They know what they are doing.", "ceCQ9BC2jjU-00039-00007542-00007752": ">> To what his situation was.", "ceCQ9BC2jjU-00040-00007752-00007896": "So let's jump into it.", "ceCQ9BC2jjU-00041-00007896-00007980": ">> Sure.", "ceCQ9BC2jjU-00042-00007980-00008290": ">> Security, it's kind of a dark and ominous", "ceCQ9BC2jjU-00043-00008290-00008457": "keynote this morning.", "ceCQ9BC2jjU-00044-00008457-00008929": "The attack's surface is growing with our homes and IOT.", "ceCQ9BC2jjU-00045-00008929-00009189": "The bad guys are getting smarter,", "ceCQ9BC2jjU-00046-00009189-00009330": "the governments are getting involved,", "ceCQ9BC2jjU-00047-00009330-00009587": "there's just not necessarily bad guys.", "ceCQ9BC2jjU-00048-00009587-00009723": "What's kind of your perspective", "ceCQ9BC2jjU-00049-00009723-00009966": "as you see it year after year acquisition?", "ceCQ9BC2jjU-00050-00009966-00010222": "40,000 professionals here focused on this problem.", "ceCQ9BC2jjU-00051-00010222-00010330": ">> We are not winning.", "ceCQ9BC2jjU-00052-00010330-00010459": ">> We are not winning?", "ceCQ9BC2jjU-00053-00010459-00010842": ">> Unfortunately, I mean, I guess as a species.", "ceCQ9BC2jjU-00054-00010950-00011034": "Again, what is it?", "ceCQ9BC2jjU-00055-00011034-00011280": "We saw a survey recently from the Ponemon Institute.", "ceCQ9BC2jjU-00056-00011280-00011451": "70% of organizations acknowledge", "ceCQ9BC2jjU-00057-00011451-00011690": "they didn't have an incident response plan.", "ceCQ9BC2jjU-00058-00011690-00011865": "So you talk about that stuff in the keynote", "ceCQ9BC2jjU-00059-00011865-00012015": "where sort of a breach was inevitable.", "ceCQ9BC2jjU-00060-00012015-00012117": "What are you going to do?", "ceCQ9BC2jjU-00061-00012117-00012202": "Well the thing you'd need to have", "ceCQ9BC2jjU-00062-00012202-00012325": "is a response plan to deal with it,", "ceCQ9BC2jjU-00063-00012325-00012454": "and 70% don't.", "ceCQ9BC2jjU-00064-00012454-00012574": "Cost of a breach also,", "ceCQ9BC2jjU-00065-00012574-00012698": "according to Ponemon Institute", "ceCQ9BC2jjU-00066-00012698-00012941": "is up to $4 million on average,", "ceCQ9BC2jjU-00067-00012941-00013169": "obviously they can be a lot larger than that.", "ceCQ9BC2jjU-00068-00013169-00013252": ">> Right.", "ceCQ9BC2jjU-00069-00013252-00013552": ">> So there's a lot of work to be done to do better.", "ceCQ9BC2jjU-00070-00013552-00013752": ">> And then you hook up a new device,", "ceCQ9BC2jjU-00071-00013752-00013897": "and they are on that new device as soon as", "ceCQ9BC2jjU-00072-00013897-00014004": "it plugs into the internet.", "ceCQ9BC2jjU-00073-00014004-00014115": "They say within an hour,", "ceCQ9BC2jjU-00074-00014115-00014358": "they ran a test today.", "ceCQ9BC2jjU-00075-00014358-00014483": "So is the,", "ceCQ9BC2jjU-00076-00014483-00014567": "I mean where are we winning,", "ceCQ9BC2jjU-00077-00014567-00014673": "Where are we getting better?", "ceCQ9BC2jjU-00078-00014673-00014946": "I mean, I've heard crazy stats that people", "ceCQ9BC2jjU-00079-00014946-00015070": "don't even know they've been breached", "ceCQ9BC2jjU-00080-00015070-00015187": "for like 245 days.", "ceCQ9BC2jjU-00081-00015187-00015271": ">> Ted: Yeah.", "ceCQ9BC2jjU-00082-00015271-00015385": ">> Is that coming down?", "ceCQ9BC2jjU-00083-00015385-00015500": "Are we getting better?", "ceCQ9BC2jjU-00084-00015500-00015892": ">> Certainly the best in the business are,", "ceCQ9BC2jjU-00085-00015892-00016103": "and really the challenge I think as an industry", "ceCQ9BC2jjU-00086-00016103-00016282": "is to percolate that down", "ceCQ9BC2jjU-00087-00016282-00016551": "through the rest of the marketplace.", "ceCQ9BC2jjU-00088-00016551-00016675": "Everybody is going to be breached,", "ceCQ9BC2jjU-00089-00016675-00016846": "so it's not whether or not you are breached,", "ceCQ9BC2jjU-00090-00016846-00017004": "it's how you deal with it come the day,", "ceCQ9BC2jjU-00091-00017004-00017126": "that's really going to differentiate", "ceCQ9BC2jjU-00092-00017126-00017345": "the good organizations from the bad ones.", "ceCQ9BC2jjU-00093-00017345-00017480": "And that's where we've been able to help", "ceCQ9BC2jjU-00094-00017480-00017600": "our customers quite a bit", "ceCQ9BC2jjU-00095-00017600-00017870": "by using our platform to help them get a consistence", "ceCQ9BC2jjU-00096-00017870-00018118": "and repeatable process for how they deal with that", "ceCQ9BC2jjU-00097-00018118-00018256": "inevitable breach when it happens.", "ceCQ9BC2jjU-00098-00018256-00018339": ">> That's interesting.", "ceCQ9BC2jjU-00099-00018339-00018528": "So how much if it is you know", "ceCQ9BC2jjU-00100-00018528-00018844": "kind of building a process for when these things happen", "ceCQ9BC2jjU-00101-00018844-00019068": "versus just the cool, sexy technology", "ceCQ9BC2jjU-00102-00019068-00019189": "that people like to talk about?", "ceCQ9BC2jjU-00103-00019189-00019283": ">> Oh, it's everything.", "ceCQ9BC2jjU-00104-00019283-00019432": "I mean one of the hottest trends that", "ceCQ9BC2jjU-00105-00019432-00019573": "you're going to be seeing all over the show", "ceCQ9BC2jjU-00106-00019573-00019731": "is automation and orchestration.", "ceCQ9BC2jjU-00107-00019731-00019884": "Which is critically important", "ceCQ9BC2jjU-00108-00019884-00020102": "as part of the sort of you get an alert", "ceCQ9BC2jjU-00109-00020102-00020311": "and how do you enrich that to understand that,", "ceCQ9BC2jjU-00110-00020311-00020431": "once you understand that", "ceCQ9BC2jjU-00111-00020431-00020618": "how can you quickly come to sort of a", "ceCQ9BC2jjU-00112-00020618-00020801": "course of action that you want to take.", "ceCQ9BC2jjU-00113-00020801-00020895": "How can you implement that", "ceCQ9BC2jjU-00114-00020895-00021117": "course of action very efficiently?", "ceCQ9BC2jjU-00115-00021117-00021249": "Those things are all important.", "ceCQ9BC2jjU-00116-00021249-00021415": "Computers can help a lot with that", "ceCQ9BC2jjU-00117-00021415-00021534": "but at the end of the day", "ceCQ9BC2jjU-00118-00021534-00021846": "it's smart people making good decisions", "ceCQ9BC2jjU-00119-00021846-00022036": "that are going to be the success factor", "ceCQ9BC2jjU-00120-00022036-00022211": "that determines how well you do.", "ceCQ9BC2jjU-00121-00022211-00022294": ">> Right, right.", "ceCQ9BC2jjU-00122-00022294-00022399": "Another kind of theme that we are hearing", "ceCQ9BC2jjU-00123-00022399-00022600": "over and over is really collaboration", "ceCQ9BC2jjU-00124-00022600-00022707": "amongst the companies", "ceCQ9BC2jjU-00125-00022707-00022819": "amongst the competitors,", "ceCQ9BC2jjU-00126-00022819-00023088": "sharing information about the threat profiles,", "ceCQ9BC2jjU-00127-00023088-00023324": "about the threats that are coming in", "ceCQ9BC2jjU-00128-00023324-00023456": "to kind of enable everybody", "ceCQ9BC2jjU-00129-00023456-00023619": "to actually kind of be on the same team.", "ceCQ9BC2jjU-00130-00023619-00023803": "That didn't always used to be the case, was it?", "ceCQ9BC2jjU-00131-00023803-00024020": ">> Well, people have been working on this for a while", "ceCQ9BC2jjU-00132-00024020-00024161": "but I think what's been a challenge", "ceCQ9BC2jjU-00133-00024161-00024531": "is getting people to feel comfortable", "ceCQ9BC2jjU-00134-00024531-00024745": "contributing their data into that data set.", "ceCQ9BC2jjU-00135-00024745-00024984": "Naturally they are very sensitive about that, right?", "ceCQ9BC2jjU-00136-00024984-00025112": ">> Right.", "ceCQ9BC2jjU-00137-00025112-00025287": ">> This is some of our most confidential information", "ceCQ9BC2jjU-00138-00025287-00025479": "that we've had a security issue", "ceCQ9BC2jjU-00139-00025479-00025679": "and we're really not you know,", "ceCQ9BC2jjU-00140-00025679-00025969": "dying to give that out to the general public.", "ceCQ9BC2jjU-00141-00025969-00026065": "And so I think it's been,", "ceCQ9BC2jjU-00142-00026065-00026202": "the industry's been trying to figure out", "ceCQ9BC2jjU-00143-00026202-00026373": "how can we show enough value back", "ceCQ9BC2jjU-00144-00026373-00026663": "when that information's contributed to some kind of a forum", "ceCQ9BC2jjU-00145-00026663-00026920": "to make people feel more comfortable about doing that?", "ceCQ9BC2jjU-00146-00026920-00027095": "So I think we've seen a little bit of progress", "ceCQ9BC2jjU-00147-00027095-00027180": "over this last year", "ceCQ9BC2jjU-00148-00027180-00027293": "and they'll be more going forward,", "ceCQ9BC2jjU-00149-00027293-00027425": "but this is a,", "ceCQ9BC2jjU-00150-00027425-00027699": "It's marathon not a sprint, I think to solve that problem.", "ceCQ9BC2jjU-00151-00027699-00028029": "But, it is crucial because if we can get to that point", "ceCQ9BC2jjU-00152-00028029-00028157": "that's what ultimately allows us", "ceCQ9BC2jjU-00153-00028157-00028328": "to turn the tables on the bad guys.", "ceCQ9BC2jjU-00154-00028328-00028493": "Because they cooperate,", "ceCQ9BC2jjU-00155-00028493-00028587": "big time,", "ceCQ9BC2jjU-00156-00028587-00028787": "they are sharing vulnerabilities,", "ceCQ9BC2jjU-00157-00028787-00028919": "they are sharing tactics,", "ceCQ9BC2jjU-00158-00028919-00029120": "they are sharing information about targets,", "ceCQ9BC2jjU-00159-00029120-00029342": "and it's only when the good guys similarly share", "ceCQ9BC2jjU-00160-00029342-00029482": "what they're experiencing that we'll have", "ceCQ9BC2jjU-00161-00029482-00029665": "that opportunity to turn the table on them.", "ceCQ9BC2jjU-00162-00029665-00029828": ">> It's funny we had a Verizon thing the other night", "ceCQ9BC2jjU-00163-00029828-00030123": "and the guy said if you are from the investigator", "ceCQ9BC2jjU-00164-00030123-00030358": "point of view, it's probably like a police investigator.", "ceCQ9BC2jjU-00165-00030358-00030486": "They see the same pattern", "ceCQ9BC2jjU-00166-00030486-00030674": "over and over and over and over and over", "ceCQ9BC2jjU-00167-00030674-00030934": "it's only when it's the first time it's happen to you", "ceCQ9BC2jjU-00168-00030934-00031066": "that's it's unique and different.", "ceCQ9BC2jjU-00169-00031066-00031186": "So really the way to kind of", "ceCQ9BC2jjU-00170-00031186-00031369": "short-circuit the whole response.", "ceCQ9BC2jjU-00171-00031369-00031481": ">> How do you find out you've been breached?", "ceCQ9BC2jjU-00172-00031481-00031579": "There is short list.", "ceCQ9BC2jjU-00173-00031579-00031818": "One, Brian Crebs, very famous reporter", "ceCQ9BC2jjU-00174-00031818-00031933": "happens to find out,", "ceCQ9BC2jjU-00175-00031933-00032016": "he tells you.", "ceCQ9BC2jjU-00176-00032016-00032203": "Number two, FBI.", "ceCQ9BC2jjU-00177-00032203-00032349": ">> They tell you.", "ceCQ9BC2jjU-00178-00032349-00032436": ">> Unfortunately, that's usually,", "ceCQ9BC2jjU-00179-00032436-00032665": "it's usually external sources like that", "ceCQ9BC2jjU-00180-00032665-00032935": "as oppose to organization internal systems", "ceCQ9BC2jjU-00181-00032935-00033082": "that tip them off to a breach.", "ceCQ9BC2jjU-00182-00033082-00033375": "Another example of how we are doing better", "ceCQ9BC2jjU-00183-00033375-00033507": "but we need to do a lot better.", "ceCQ9BC2jjU-00184-00033507-00033643": ">> And then there's this whole thing coming up", "ceCQ9BC2jjU-00185-00033643-00033767": "called IOT, right.", "ceCQ9BC2jjU-00186-00033767-00034062": "And 5G and all these connected device in the home,", "ceCQ9BC2jjU-00187-00034062-00034287": "our cars, our nest,", "ceCQ9BC2jjU-00188-00034287-00034502": "So the attacks surface gets giant.", "ceCQ9BC2jjU-00189-00034502-00034706": "Like I said, they said in the keynote,", "ceCQ9BC2jjU-00190-00034706-00034887": "you plug something in the internet", "ceCQ9BC2jjU-00191-00034887-00035002": "they are on it within an hour.", "ceCQ9BC2jjU-00192-00035002-00035146": "How does that really change", "ceCQ9BC2jjU-00193-00035146-00035382": "the way that you kind of think about the problem?", "ceCQ9BC2jjU-00194-00035382-00035484": ">> It makes it a lot harder.", "ceCQ9BC2jjU-00195-00035484-00035736": "The attack surface gets harder, gets bigger,", "ceCQ9BC2jjU-00196-00035736-00036075": "the potential risks go up quite a bit, right.", "ceCQ9BC2jjU-00197-00036075-00036342": "I mean you are talking about heart implants,", "ceCQ9BC2jjU-00198-00036342-00036468": "or things like that which may have", "ceCQ9BC2jjU-00199-00036468-00036648": "connectivity to some degree,", "ceCQ9BC2jjU-00200-00036648-00036926": "then obviously the stakes are severe.", "ceCQ9BC2jjU-00201-00036926-00037152": "But the thing that makes those devices even trickier", "ceCQ9BC2jjU-00202-00037152-00037335": "is so often they're embedded systems,", "ceCQ9BC2jjU-00203-00037335-00037600": "and so unlike your Windows PC's or your Mac where,", "ceCQ9BC2jjU-00204-00037600-00037764": "I mean it's updating itself all the time.", "ceCQ9BC2jjU-00205-00037764-00037848": ">> Right, right.", "ceCQ9BC2jjU-00206-00037848-00037931": ">> And you barely even think about it,", "ceCQ9BC2jjU-00207-00037931-00038084": "you turn it on one morning and there is a new update.", "ceCQ9BC2jjU-00208-00038084-00038345": "A little harder to make those update happen", "ceCQ9BC2jjU-00209-00038345-00038537": "on IOT kinds of devices,", "ceCQ9BC2jjU-00210-00038537-00038746": "either because they're harder to get to", "ceCQ9BC2jjU-00211-00038746-00038857": "or the system's aren't as open", "ceCQ9BC2jjU-00212-00038857-00039100": "or people aren't use to allowing those updates to occur.", "ceCQ9BC2jjU-00213-00039100-00039420": "So even though we may know about the vulnerabilities", "ceCQ9BC2jjU-00214-00039420-00039608": "patching them up is even harder", "ceCQ9BC2jjU-00215-00039608-00039942": "in an IOT environment typically than in a traditional.", "ceCQ9BC2jjU-00216-00039942-00040025": ">> It's crazy.", "ceCQ9BC2jjU-00217-00040025-00040144": "Alright, so give us a little update on Resilient.", "ceCQ9BC2jjU-00218-00040144-00040318": "What exactly is do you guys do", "ceCQ9BC2jjU-00219-00040318-00040663": "inside this crazy eco-system of protecting us all?", "ceCQ9BC2jjU-00220-00040663-00040747": ">> Sure.", "ceCQ9BC2jjU-00221-00040747-00040830": "So five or six years ago,", "ceCQ9BC2jjU-00222-00040830-00041047": "myself and my co-founder John started the company", "ceCQ9BC2jjU-00223-00041047-00041191": "and it was really was acknowledging", "ceCQ9BC2jjU-00224-00041191-00041350": "that we've gone through the era of prevention,", "ceCQ9BC2jjU-00225-00041350-00041627": "to detection and now it's all about response.", "ceCQ9BC2jjU-00226-00041627-00041724": "And at the end of the day", "ceCQ9BC2jjU-00227-00041724-00041900": "when organizations were trying to deal with that", "ceCQ9BC2jjU-00228-00041900-00042081": "we saw them using ticketing systems,", "ceCQ9BC2jjU-00229-00042081-00042317": "spreadsheet, email, chat", "ceCQ9BC2jjU-00230-00042317-00042408": "I mean a mess.", "ceCQ9BC2jjU-00231-00042408-00042571": "And so we built our platform,", "ceCQ9BC2jjU-00232-00042571-00042726": "the Resilient IRP from the ground up", "ceCQ9BC2jjU-00233-00042726-00042934": "specifically to help them tie together", "ceCQ9BC2jjU-00234-00042934-00043089": "the people processing in technology", "ceCQ9BC2jjU-00235-00043089-00043232": "around incident response.", "ceCQ9BC2jjU-00236-00043232-00043376": "And that's gone amazing.", "ceCQ9BC2jjU-00237-00043376-00043504": "I mean the growth that we've seen", "ceCQ9BC2jjU-00238-00043504-00043775": "even before the IBM acquisition but afterwards", "ceCQ9BC2jjU-00239-00043775-00043903": "has been breath taking.", "ceCQ9BC2jjU-00240-00043903-00044092": "And more recently we been adding", "ceCQ9BC2jjU-00241-00044092-00044236": "more and more intelligence in", "ceCQ9BC2jjU-00242-00044236-00044503": "automation and orchestration into the platform,", "ceCQ9BC2jjU-00243-00044503-00044737": "to help not only advise people what to do,", "ceCQ9BC2jjU-00244-00044737-00044864": "which we've done forever,", "ceCQ9BC2jjU-00245-00044864-00044947": "but help them do it,", "ceCQ9BC2jjU-00246-00044947-00045137": "click a bottom and we'll deploy that patch", "ceCQ9BC2jjU-00247-00045137-00045514": "or we'll revoke that user's privileges or what have you.", "ceCQ9BC2jjU-00248-00045514-00045597": ">> Right.", "ceCQ9BC2jjU-00249-00045597-00045711": "Yeah a lot of conversation about kind of", "ceCQ9BC2jjU-00250-00045711-00045828": "evolution of big data,", "ceCQ9BC2jjU-00251-00045828-00046002": "evolution of things like Sparks", "ceCQ9BC2jjU-00252-00046002-00046183": "so that you know can react in real time", "ceCQ9BC2jjU-00253-00046183-00046461": "as opposed to kind of looking back after the fact", "ceCQ9BC2jjU-00254-00046461-00046594": "and then trying to go and sell something.", "ceCQ9BC2jjU-00255-00046594-00046677": ">> For sure.", "ceCQ9BC2jjU-00256-00046677-00046800": "And for us it's really empowering that human.", "ceCQ9BC2jjU-00257-00046800-00047012": "It's either the enrichment activity", "ceCQ9BC2jjU-00258-00047012-00047197": "where they'd normally go to 10 different screens,", "ceCQ9BC2jjU-00259-00047197-00047486": "to look up different data about a malware thread", "ceCQ9BC2jjU-00260-00047486-00047601": "or about vulnerabilities,", "ceCQ9BC2jjU-00261-00047601-00047776": "we just spoon feed that to them", "ceCQ9BC2jjU-00262-00047776-00047861": "right within the platforms", "ceCQ9BC2jjU-00263-00047861-00047967": "so they don't have to have those", "ceCQ9BC2jjU-00264-00047967-00048107": "10 tabs opened in the browser.", "ceCQ9BC2jjU-00265-00048107-00048274": "And after they'd had a chance to evaluate that,", "ceCQ9BC2jjU-00266-00048274-00048396": "and they want to know what to do,", "ceCQ9BC2jjU-00267-00048396-00048576": "again they don't have to go to another tool", "ceCQ9BC2jjU-00268-00048576-00048711": "and make that action happen,", "ceCQ9BC2jjU-00269-00048711-00048890": "they can as click a button within Resilient", "ceCQ9BC2jjU-00270-00048890-00049046": "and we'll do that for them.", "ceCQ9BC2jjU-00271-00049046-00049130": ">> Alright.", "ceCQ9BC2jjU-00272-00049130-00049213": "Ted Julian, we are rooting for you.", "ceCQ9BC2jjU-00273-00049213-00049296": ">> Ted: Thanks, yeah.", "ceCQ9BC2jjU-00274-00049296-00049391": ">> IBM, give him some more recourses.", "ceCQ9BC2jjU-00275-00049391-00049524": "He's Ted Julian and I'm Jeff Frick.", "ceCQ9BC2jjU-00276-00049524-00049610": "You're watching theCUBE", "ceCQ9BC2jjU-00277-00049610-00049695": "at RSA Conference 2017,", "ceCQ9BC2jjU-00278-00049695-00049865": "at Moscone Center,", "ceCQ9BC2jjU-00279-00049865-00049948": "San Francisco.", "ceCQ9BC2jjU-00280-00049948-00050115": "Thanks for watching."}}, {"audio_id": "ceQAnn_ywq8", "text": {"ceQAnn_ywq8-00000-00000131-00000252": "1 IF WE CAN GET EVERYBODY TO TAKE", "ceQAnn_ywq8-00001-00000252-00000660": "THEIR SEATS WE'LL GET STARTED. FOR THOSE OF YOU STANDING IN THE", "ceQAnn_ywq8-00002-00000660-00000974": "BACK, THERE ARE VARIOUS SEATS INCLUDING IN THE FRONT ROW THAT", "ceQAnn_ywq8-00003-00000974-00001220": "ARE MARKED RESERVED. THEY'RE NOT RESERVED ANYMORE.", "ceQAnn_ywq8-00004-00001220-00001569": "FEEL FREE TO TAKE THEM. THERE ARE ALSO, I SEE, A HANDFUL", "ceQAnn_ywq8-00005-00001569-00001989": "OF SEATS ON THE SIDES AS YOU COME DOWN.", "ceQAnn_ywq8-00006-00001989-00002271": "FIND YOUR SEATS DURING THESE INTRODUCTORY REMARKS.", "ceQAnn_ywq8-00007-00002271-00002961": "LET MY START OFF BY WELCOMING YOU TO THE 2009 TRENT LECTURE.", "ceQAnn_ywq8-00008-00002961-00003451": "OBVIOUSLY, IT IS NOW 2010. AND NOT SURPRISINGLY THERE IS A", "ceQAnn_ywq8-00009-00003451-00003856": "STORY BEHIND THAT. BUT FIRST, LET ME TELL YOU A FEW", "ceQAnn_ywq8-00010-00003856-00004379": "THINGS ABOUT THE JEFFREY TRENT LECTURE AND CANS RESEARCH.", "ceQAnn_ywq8-00011-00004379-00004777": "JEFF TRENT WAS THE FOUNDING SCIENTIFIC DIRECTOR OF THE", "ceQAnn_ywq8-00012-00004777-00005291": "NATIONAL HUMAN GENOME RESEARCH INSTITUTED, CAME IN 1993 TO", "ceQAnn_ywq8-00013-00005291-00005622": "START A PROGRAM FROM SCRATCH. HE WAS RECRUITED BY FRANCIS", "ceQAnn_ywq8-00014-00005622-00006002": "COLLINS, WHO WAS THE PREVIOUS HEAD OF THE NATIONAL HUMAN", "ceQAnn_ywq8-00015-00006002-00006443": "GENOME RESEARCH INSTITUTE, PART OF THE RECRUITMENT WAS GIVEN THE", "ceQAnn_ywq8-00016-00006443-00006729": "ABILITY TO START AN INTRAMURAL PROGRAM FOCUSED ON GENOMICS", "ceQAnn_ywq8-00017-00006729-00007225": "RESEARCH. HE ARRIVED HERE, FROM 1993 AND", "ceQAnn_ywq8-00018-00007225-00007531": "2002. DID A SPECTACULAR JOB OF LEADING", "ceQAnn_ywq8-00019-00007531-00007784": "OUR INTRAMURAL PROGRAM AND STARTING IT FROM SCRATCH,", "ceQAnn_ywq8-00020-00007784-00008297": "BUILDING IT UP, MAKING IT A WORLD CLASS PROGRAM IN GENETICS", "ceQAnn_ywq8-00021-00008297-00008665": "AND GENOMICS RESEARCH. HE DEPARTED IN 2002.", "ceQAnn_ywq8-00022-00008665-00009221": "AT A TIME, I BECAME THE SCIENTIFIC DIRECTOR AND ONE OF", "ceQAnn_ywq8-00023-00009221-00009634": "THE FIRST THINGS I DID WAS TO ESTABLISH A LECTURESHIP IN HIS", "ceQAnn_ywq8-00024-00009634-00009913": "NAME. AND THIS IS THE JEFFREY M. TRENT", "ceQAnn_ywq8-00025-00009913-00010404": "LECTURE IN CANCER RESERACH. 2 THIS IS NOW THE 7th SUCH", "ceQAnn_ywq8-00026-00010404-00010642": "LECTURE. AND YOU CAN SEE THE IMPRESSIVE", "ceQAnn_ywq8-00027-00010642-00010893": "GROUP OF INDIVIDUALS THAT HAVE GIVEN THE PREVIOUS 6.", "ceQAnn_ywq8-00028-00010893-00011440": "AND THE 7th AS YOU WILL KNOW AND FIND OUT IT'S NO EXCEPTION", "ceQAnn_ywq8-00029-00011440-00011717": "TO THAT TREND. THERE ARE A COUPLE OF STORIES I", "ceQAnn_ywq8-00030-00011717-00012017": "WANTED TO TELL BEFORE I TURN THIS OVER TO THE INDIVIDUAL WHO", "ceQAnn_ywq8-00031-00012017-00012235": "CAN S GOING TO INTRODUCE THIS YEAR'S LECTURER.", "ceQAnn_ywq8-00032-00012235-00012671": "THERE ARE 3 OF US YOU'RE GOING TO SEE ON THE STAGE.", "ceQAnn_ywq8-00033-00012671-00013175": "MYSELF, ERIC GREEN, AND NEXT FROM KATHY HUDSON AND THEN HEAR", "ceQAnn_ywq8-00034-00013175-00013454": "FROM CAROL W. GREIDER. A YEAR AGO, IF YOU THINK BACK OR", "ceQAnn_ywq8-00035-00013454-00013756": "ROUGHLY A YEAR AGO, EACH OF OUR 3 LIVES WERE A LITTLE BIT", "ceQAnn_ywq8-00036-00013756-00014087": "DIFFERENT. AT THAT TIME I WAS A SCIENTIFIC", "ceQAnn_ywq8-00037-00014087-00014304": "DIRECTOR OF THE INSTITUTE, NOW I'M THE DIRECTOR OF THE", "ceQAnn_ywq8-00038-00014304-00014690": "INSTITUTE. CAROL W. GREIDER WAS A FACULTY", "ceQAnn_ywq8-00039-00014690-00015390": "MEMBER AT JOHNS HOPKINS. SHE'S NOW THE CHIEF OF STAFF", "ceQAnn_ywq8-00040-00015512-00015806": "HERE AT NIH. OUR SPEAKER WAS JUST A WORLD", "ceQAnn_ywq8-00041-00015806-00016218": "CLASS RESEARCHER, AND PROMINENT MEMBER OF THE RESEARCH COMMUNITY", "ceQAnn_ywq8-00042-00016218-00016729": "WHICH IS WHY WE INVITED HER A YEAR OR SO TO COME GIVE THE", "ceQAnn_ywq8-00043-00016729-00017225": "7th JEFFREY TRENT LECTURE. HER LIFE HAS CHANGED A BIT.", "ceQAnn_ywq8-00044-00017225-00017659": "AN EVENT THAT HAVE INFLUENCED THIS LECTURE SUBSTANTIALLY.", "ceQAnn_ywq8-00045-00017659-00018042": "IT WILL SEEM THAT THE 3 OF US, KATHY HUDSON MYSELF, AND CAROL", "ceQAnn_ywq8-00046-00018042-00018490": "W. GREIDER AND THE ENTIRE NHGRI SHOULD BE A SIMPLE ACTIVITY TO", "ceQAnn_ywq8-00047-00018490-00018737": "PUT ON A LECTURE. I WILL TELL YOU IN ALL OF MY", "ceQAnn_ywq8-00048-00018737-00019173": "YEARS IN ORGANIZING, THIS HAS BEEN THE MOST CHALLENGING ONE TO", "ceQAnn_ywq8-00049-00019173-00019428": "HAVE HAPPEN. AND WE WEREN'T EVEN SUCCESSFUL", "ceQAnn_ywq8-00050-00019428-00019798": "AFTER HAVING IT HAPPEN IN 2009. 3 IT'S TAKEN US ALL THE WAY DO", "ceQAnn_ywq8-00051-00019798-00019917": "2010. WHY IS THAT?", "ceQAnn_ywq8-00052-00019917-00020312": "IF YOU LOOK AT YOUR PROGRAM, YOU WILL NOTE THAT THE DATE ON THIS", "ceQAnn_ywq8-00053-00020312-00020534": "LECTURE WAS TUESDAY, SEPTEMBER 29.", "ceQAnn_ywq8-00054-00020534-00021029": "THAT WAS THE ORIGINAL DATE TO HAVE CAROL COME HERE AND GIVE", "ceQAnn_ywq8-00055-00021029-00021293": "THE LECTURE. IT WAS SUCH AN INNOCENT DATE", "ceQAnn_ywq8-00056-00021293-00021695": "WHEN WE SELECTED IT. IT WAS GOOD FOR OUR CALENDARS.", "ceQAnn_ywq8-00057-00021695-00022098": "THAT SEEMS GOOD ENOUGH. ABOUT A DAY OR 2 BEFORE", "ceQAnn_ywq8-00058-00022098-00022592": "SEPTEMBER 29, WE GOT A CALL THAT BASICALLY INFORMED US THERE WAS", "ceQAnn_ywq8-00059-00022592-00022962": "GOING TO BE A VERY, VERY, VERY, VERY, VERY HIGH LEVEL VISITOR TO", "ceQAnn_ywq8-00060-00022962-00023376": "THE NIH. AND THAT THE AUDITORIUM WAS NOT", "ceQAnn_ywq8-00061-00023376-00023698": "AVAILABLE TO US ANYMORE. AND IT WAS IN OUR BEST INTEREST", "ceQAnn_ywq8-00062-00023698-00024187": "TO POSTPONE THIS TALK. WE DID THAT.", "ceQAnn_ywq8-00063-00024187-00024435": "AND ORIGINALLY, IT WAS SUPPOSED TO BE A DIFFERENT VISITOR, NOT", "ceQAnn_ywq8-00064-00024435-00024753": "THE VERY, VERY, VERY TOP ONE BUT THE NEXT ONE DOWN, AND IT WAS", "ceQAnn_ywq8-00065-00024753-00025123": "SUPPOSED TO BE SEPTEMBER 29. IT WASN'T.", "ceQAnn_ywq8-00066-00025123-00025503": "THAT VISITOR CAME, BUT IT WAS THE NEXT DAY.", "ceQAnn_ywq8-00067-00025503-00025806": "BUT WHAT I DID FIND OUT WAS THAT WE COULDN'T HAVE USED THE", "ceQAnn_ywq8-00068-00025806-00026185": "AUDITORIUM ON SEPTEMBER 29. WHEN THE PRESIDENT OF THE UNITED", "ceQAnn_ywq8-00069-00026185-00026538": "STATES VISITS YOU, THEY LOCK THE ROOM DOWN, THEY HAVE DOGS IN", "ceQAnn_ywq8-00070-00026538-00026822": "HERE -- THEY HAVE DOGS IN HERE SNIFFING.", "ceQAnn_ywq8-00071-00026822-00027293": "SO WE GOT KICKED OUT OF THIS ROOM BY THE WHITE HOUSE.", "ceQAnn_ywq8-00072-00027293-00027644": "CAROL WAS VERY GRACIOUS, SHE SAID NOT A BIG DEAL.", "ceQAnn_ywq8-00073-00027644-00028202": "WE'LL FIND ANOTHER DATE. WE, ONCE AGAIN, PICKED A NICE", "ceQAnn_ywq8-00074-00028202-00028543": "DATE, HAPPENED TO BE I THINK IT WAS DECEMBER 8 OR SOMETHING LIKE", "ceQAnn_ywq8-00075-00028543-00028813": "THAT. 4 IT LOOKED GOOD ON MY CALENDAR,", "ceQAnn_ywq8-00076-00028813-00029178": "AND OTHER HERS. AND OFF WE WENT, ALL SET TO DO", "ceQAnn_ywq8-00077-00029178-00029363": "THIS. I DIDN'T FEEL TOO BAD.", "ceQAnn_ywq8-00078-00029363-00029766": "IT WAS STILL 2009. BUT THEN CAROL HAD TO WIN A", "ceQAnn_ywq8-00079-00029766-00030147": "NOBLE PRIZE. SHE HAD TO GO TO SWEDEN FOR THAT", "ceQAnn_ywq8-00080-00030147-00030595": "WEEK. I UNDERSTOOD WHEN SHE CALLED ME", "ceQAnn_ywq8-00081-00030595-00031000": "TO SAY WE'RE GOING TO HAVE TO POSTPONE THIS AGAIN.", "ceQAnn_ywq8-00082-00031000-00031243": "BUT THE GOOD NEWS, IT BRINGS US TO TODAY.", "ceQAnn_ywq8-00083-00031243-00031544": "AND IN THE EFFORT OF BEING GREEN.", "ceQAnn_ywq8-00084-00031544-00031822": "WE DECIDED NOT TO REPRINT THESE PROGRAMS.", "ceQAnn_ywq8-00085-00031822-00032158": "SO I DO APOLOGIZE FOR THE FACT THAT THEY DON'T HAVE TODAY'S", "ceQAnn_ywq8-00086-00032158-00032393": "DATE ON THEM. BUT WE LEFT IT AS SEPTEMBER,", "ceQAnn_ywq8-00087-00032393-00032766": "2009 DATE. AT LEAST IT WAS -- SEEMED LIKE A", "ceQAnn_ywq8-00088-00032766-00033106": "GREEN THING TO DO, A MOW MENO TO THIS TOGETHER OF 2", "ceQAnn_ywq8-00089-00033106-00033761": "CANCELLATIONS. SO WITH THAT SAID, AND THAT", "ceQAnn_ywq8-00090-00033761-00034153": "EXPLANATION OF BOTH HOW WE GOT HERE AND THE RICH HISTORY OF", "ceQAnn_ywq8-00091-00034153-00034450": "THIS LECTURE SERIES, I'M NOW GOING TO TURN THE PODIUM TO", "ceQAnn_ywq8-00092-00034450-00034847": "KATHY HUDSON WHO HAS A LONG CONNECTION TO THE SPEAKER AND", "ceQAnn_ywq8-00093-00034847-00035547": "WILL INTRODUCE HER TODAY. THANK YOU.", "ceQAnn_ywq8-00094-00036162-00036428": ">> IT'S MY PLEASURE TO BE ABLE TO INTRODUCE CAROL W. GREIDER TO", "ceQAnn_ywq8-00095-00036428-00036796": "YOU TODAY. CAROL AND I HAVE BEEN FRIENDS", "ceQAnn_ywq8-00096-00036796-00037063": "FOR 25 YEARS. WE FIRST MET AS GRADUATE", "ceQAnn_ywq8-00097-00037063-00037412": "STUDENTS AT THE UNIVERSITY OF CALIFORNIA, BERKELEY WHEN I", "ceQAnn_ywq8-00098-00037412-00037721": "STARTED GRADUATE SCHOOL THERE SHE WAS ALREADY THERE.", "ceQAnn_ywq8-00099-00037721-00038172": "TOILING AWAY. AND WELL ON HER WAY TO THE FIRST", "ceQAnn_ywq8-00100-00038172-00038444": "CELL PUBLICATION. 5 THIS SHOULD BE INSPIRING TO ALL", "ceQAnn_ywq8-00101-00038444-00038862": "THE GRADUATE STUDENTS AMONG YOU. THIS IS A PICTURE OF CAROL AT", "ceQAnn_ywq8-00102-00038862-00039300": "THE LAB BENCH IN 1985. AND WE WORKED IN A VERY SMALL", "ceQAnn_ywq8-00103-00039300-00039666": "DEPARTMENT, A DOUBLE MEMBERS ARE HERE WITH -- COUPLE MEMBERS ARE", "ceQAnn_ywq8-00104-00039666-00039874": "HERE WITH US TODAY. WHERE THE STUDENTS, POST-DOCS", "ceQAnn_ywq8-00105-00039874-00039931": "AND FACULTY WERE A CLOSELY TIGHT GROUP.", "ceQAnn_ywq8-00106-00039931-00040559": "WE HAD A PARTY, SOMETIMES 2 ON A WEEKEND, OR IF WE WERE HAVING A", "ceQAnn_ywq8-00107-00040559-00041253": "SEMINAR WE DIDN'T HAVE MUCH E-MAIL BACK THEN, WE JUST POSTED", "ceQAnn_ywq8-00108-00041253-00041878": "SIGNS AROUND IN THE BUILDING. THIS IS A STUDENT SEMINAR SIGN", "ceQAnn_ywq8-00109-00041878-00042331": "FROM A VERY IMPORTANT PRESENTATION THAT CAROL GAVE", "ceQAnn_ywq8-00110-00042331-00042609": "ASKING THE IMPORTANT QUESTION, HOW CRUDE DO TELOMER EXTRACTS", "ceQAnn_ywq8-00111-00042609-00042825": "GET. THERE IS A COUPLE OF FEATURES.", "ceQAnn_ywq8-00112-00042825-00043228": "THIS IS THE SUPER COIL DENSITY. HER NICKNAME WAS SUPER COIL.", "ceQAnn_ywq8-00113-00043228-00043928": "AND ON THE FIGURE B YOU CAN SEE A FIGURE REPRESENTING WHAT WAS", "ceQAnn_ywq8-00114-00044187-00044378": "LATER TO BECOME NAMED TELOMERASE.", "ceQAnn_ywq8-00115-00044378-00045078": "WHAT YOU CAN'T READ IN THIS SLIDE, BUT I'D LIKE FEW READ AN", "ceQAnn_ywq8-00116-00045153-00045853": "EXCERPT, AN ABSTRACT THAT HER FRIENDS, I THINK IT WAS CLAIRE", "ceQAnn_ywq8-00117-00045855-00046230": "WHO YOU'LL SEE PHOTOGRAPHED LATER WHO WROTE THIS FOR HER", "ceQAnn_ywq8-00118-00046230-00046522": "UPCOMING CELL PAPER. IT WAS TITLED PARTIALLY PURIFIED", "ceQAnn_ywq8-00119-00046522-00046941": "FACTORS FROM TETRAHYMENA DO NIFTY THINGS IN TEST TUBES.", "ceQAnn_ywq8-00120-00046941-00047361": "TELOMERASES MUST EXIST. GIVEN THAT, THEY MUST COME FROM", "ceQAnn_ywq8-00121-00047361-00047687": "SOMEWHERE, CONSIDERING CELLS DIVIDE AND MAKE CHROMOSOMES", "ceQAnn_ywq8-00122-00047687-00048025": "NEEDING MORE TELOMERS. DO THEY BUY THEM FROM YEAST.", "ceQAnn_ywq8-00123-00048025-00048241": "ILLUSION TO JACK, WHO SHARED THE NOBLE PRIZE FROM CAROL.", "ceQAnn_ywq8-00124-00048241-00048430": "DOES GOD MAKE TELOMERES? HE DOES UNDOUBTEDLY BUT ISN'T", "ceQAnn_ywq8-00125-00048430-00048837": "TELLING HOW OR DOESN'T CALL THEM 6 THAT.", "ceQAnn_ywq8-00126-00048837-00049290": "YOU WILL HAVE TO READ GOD'S PAPER, SUPREME BEING, TO FIND", "ceQAnn_ywq8-00127-00049290-00049828": "OUT WHAT TELOMERES ARE CALLED. IF DO YOU THE RIGHT THING,", "ceQAnn_ywq8-00128-00049828-00050221": "TETRAHYMENA WILL MAKE TELOMERS FOR YOU.", "ceQAnn_ywq8-00129-00050221-00050688": "IF GELS LOOK GREAT. ALL THE CONTROLS TURNED OUT", "ceQAnn_ywq8-00130-00050688-00050828": "RIGHT. THEY DID.", "ceQAnn_ywq8-00131-00050828-00051416": "SO HERE IS ANOTHER PICTURE OF CAROL IN THE DAY WITH AN UGLY", "ceQAnn_ywq8-00132-00051416-00051939": "BUT IMPORTANT GEL. AND BEING HER FRIEND FOR A LONG", "ceQAnn_ywq8-00133-00051939-00052462": "TIME, I'VE BEEN TRYING TO UNDERSTAND THE KEY INGREDIENTS", "ceQAnn_ywq8-00134-00052462-00053069": "FOR HER INCREDIBLE SCIENTIFIC SUCCESS. THIS IS A PHOTOGRAPH", "ceQAnn_ywq8-00135-00053069-00053654": "TAKEN IN MY BACKYARD IN THE MID 80s.", "ceQAnn_ywq8-00136-00053654-00053852": "AND YOU CAN SEE CAROL PICTURED THERE.", "ceQAnn_ywq8-00137-00053852-00054094": "WE ALSO SEE PICTURED THERE [LAUGHTER]", "ceQAnn_ywq8-00138-00054094-00054594": "ONE OF THE KEY INGREDIENTS FOR SCIENTIFIC SUCCESS, FRIENDS AND", "ceQAnn_ywq8-00139-00054594-00054851": "BEER. AND MANY PICTURES THAT I HAVE OF", "ceQAnn_ywq8-00140-00054851-00055026": "CAROL, THERE IS ALSO THIS INTERESTING BOOK, A DICTIONARY.", "ceQAnn_ywq8-00141-00055026-00055726": "MAYBE CAROL WILL EXPLAIN IT TO YOU.", "ceQAnn_ywq8-00142-00055817-00056294": "SO SADLY, CAROL STARTED BEFORE ME AND LEFT WELL BEFORE ME AT", "ceQAnn_ywq8-00143-00056294-00056735": "BERKELEY. AND IN 1988, JIM WATSON HAD A", "ceQAnn_ywq8-00144-00056735-00057039": "PARTICULARLY GOOD IDEA. HE HAD HAD GOOD IDEAS", "ceQAnn_ywq8-00145-00057039-00057222": "PREVIOUSLY. INCLUDING THOSE ASSOCIATED WITH", "ceQAnn_ywq8-00146-00057222-00057526": "THE STRUCTURE OF DNA. HE HAD A REALLY GREAT IDEA IN", "ceQAnn_ywq8-00147-00057526-00058129": "1988 WHICH WAS TO BRING CAROL AS A FELLOW, A SUPER POST-DOC", "ceQAnn_ywq8-00148-00058129-00058348": "POSITION. SO WE HAD TO SAY GOODBYE TO HER,", "ceQAnn_ywq8-00149-00058348-00058483": "BUT NOT FOR LONG. WE STAYED VERY CLOSE IN TOUCH.", "ceQAnn_ywq8-00150-00058483-00059029": "ONE OF THE FIRST TIMES WE GOT 7 TOGETHER AFTER I LEFT GRADUATE", "ceQAnn_ywq8-00151-00059029-00059654": "SCHOOL IN 1989 WAS TO GO ON A BIKE TRIP TO ALASKA.", "ceQAnn_ywq8-00152-00059654-00060048": "THIS PICTURE SHOWS THE ROUTE THAT WE TOOK.", "ceQAnn_ywq8-00153-00060048-00060211": "I DON'T KNOW HOW TO GET A POINTER TO WORK.", "ceQAnn_ywq8-00154-00060211-00060411": "BUT WE BIKED FROM ANCHORAGE ALL THE WAY AROUND THAT DOTTED LINE", "ceQAnn_ywq8-00155-00060411-00061111": "TO VALDEZ. AND ON THAT BIKE TRIP, I HAVE NO", "ceQAnn_ywq8-00156-00061151-00061650": "PICTURES OF CAROL ON A BIKE AT ALL.", "ceQAnn_ywq8-00157-00061650-00061930": "I HAVE PICTURES OF CLAIRE WHO WROTE THE ABSTRACT AND HER", "ceQAnn_ywq8-00158-00061930-00062070": "HUSBAND ROLAND, AND MY NOW HUSBAND JOE.", "ceQAnn_ywq8-00159-00062070-00062370": "BUT I HAVE NO PICTURES OF CAROL ON A BIKE AT ALL.", "ceQAnn_ywq8-00160-00062370-00062788": "THE REASON IS BECAUSE WHEN WE SADDLED UP OUR BIKES, CAROL WAS", "ceQAnn_ywq8-00161-00062788-00063198": "OFF LIKE A SHOT. SHE ROAD BICYCLE LIKE SHE DOES", "ceQAnn_ywq8-00162-00063198-00063616": "HER SCIENCE, FAST AND FURIOUS. WE ONLY MANAGED TO CATCH UP WITH", "ceQAnn_ywq8-00163-00063616-00064217": "HER IN THE EVENINGS, AGAIN WITH THAT KEY INGREDIENT, BEER.", "ceQAnn_ywq8-00164-00064217-00064801": "WE FINISHED THE BIKE TRIP, TOOK A FERRY FROM VELOCITIES, TOOK A", "ceQAnn_ywq8-00165-00064801-00065501": "TRAIN, AND TACKLED GLACIAL RIVERS, AND BEER INFESTED WOODS", "ceQAnn_ywq8-00166-00065643-00066049": "AND HAD A GREAT TIME TOGETHER. IN THE INTERVENING YEARS, CAROL", "ceQAnn_ywq8-00167-00066049-00066616": "AND I HAVE SHARED HOLIDAYS, VACATIONS, RAISING FAMILIES", "ceQAnn_ywq8-00168-00066616-00066970": "TOGETHER. WE'VE BEEN COLLEAGUES TOGETHER", "ceQAnn_ywq8-00169-00066970-00067333": "AT HOPKINS. AND SO CAROL ROSE QUICKLY", "ceQAnn_ywq8-00170-00067333-00067770": "THROUGH THE SCIENTIFIC RANKS BECOME THE NATHANS PROFESSOR AND", "ceQAnn_ywq8-00171-00067770-00068407": "THE CHAIR OF THE DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS.", "ceQAnn_ywq8-00172-00068407-00068836": "SO DURING THIS TIME WE HAVE BEEN FRIENDS OF COURSE I'VE", "ceQAnn_ywq8-00173-00068836-00068954": "ACCUMULATED MANY HUNDREDS OF PHOTOGRAPHS.", "ceQAnn_ywq8-00174-00068954-00069301": "ERIC WOULDN'T LET ME SHOW ALL OF THEM TODAY.", "ceQAnn_ywq8-00175-00069301-00069504": "I WANTED TO SHOW YOU A COUPLE 8 PICTURES WHERE I HAD THE", "ceQAnn_ywq8-00176-00069504-00069954": "PLEASURE OF BEING A GUEST OF CAROL'S AS SHE RECEIVED THE", "ceQAnn_ywq8-00177-00069954-00070450": "NOBEL PRIZE. THIS IS THE AUDITORIUM WHERE THE NOBEL", "ceQAnn_ywq8-00178-00070450-00070788": "PRIZES ARE GIVEN OUT. WHAT YOU CAN SEE IN THE TOP", "ceQAnn_ywq8-00179-00070788-00071304": "LAYER THERE IS A FULL ORCHESTRA THAT PERFORMED DURING THE COURSE", "ceQAnn_ywq8-00180-00071304-00071512": "OF THE CEREMONY. DOWN BELOW ARE THE NOBLE", "ceQAnn_ywq8-00181-00071512-00071848": "COMMITTEE AND SITTING IN THE FRONT ON THE RIGHT IS THE", "ceQAnn_ywq8-00182-00071848-00072193": "SWEDISH ROYAL FAMILY. ON THE LEFT ARE THE NOBLE", "ceQAnn_ywq8-00183-00072193-00072676": "LAUREATES FROM THIS YEAR. IF YOU ZOOM IN YOU CAN SEE A", "ceQAnn_ywq8-00184-00072676-00073056": "BUST OF ALFRED NOBLE AND SEE THAT THERE IS GREEN AND WHITE", "ceQAnn_ywq8-00185-00073056-00073485": "DECORATING ABOVE THE STAGE AND ALONG THE BASE OF THE STAGE AND", "ceQAnn_ywq8-00186-00073485-00073573": "ALL OVER. IT TURNS OUT THOSE ARE FLOWERS", "ceQAnn_ywq8-00187-00073573-00074273": "THAT WERE CUT FROM ITALIAN VILLA WHERE ALFRED NOBLE VACATIONED.", "ceQAnn_ywq8-00188-00074367-00075067": "THE WHOLE ROOM HAD THE SMELL OF THESE FLOWERS.", "ceQAnn_ywq8-00189-00075332-00075357": "AND HERE IS CAROL, RECEIVING HER NOBLE.", "ceQAnn_ywq8-00190-00075351-00075376": "HAVING SUCCESSFULLY WALKED, WALKED, WALKED, BOWED, BOWED,", "ceQAnn_ywq8-00191-00075369-00075394": "BOWED. [LAUGHTER]", "ceQAnn_ywq8-00192-00075376-00075897": "SO THIS IS WHERE THE DINNER WAS FOLLOWING THE NOBLE CEREMONY.", "ceQAnn_ywq8-00193-00075897-00076318": "IN THE CENTER TABLE WAS FOR THE IMPORTANT PEOPLE AND THEN ON THE", "ceQAnn_ywq8-00194-00076318-00076437": "SIDES WHERE THE PEOPLE FOR LESS IMPORTANT.", "ceQAnn_ywq8-00195-00076437-00076892": "THEY WERE GRADIENT. AND THE LESS IMPORTANT YOU WERE,", "ceQAnn_ywq8-00196-00076892-00077214": "THE FURTHER OUT YOU WERE AT THESE TABLES.", "ceQAnn_ywq8-00197-00077214-00077443": "[LAUGHTER] CAROL HAD DINNER WITH THE", "ceQAnn_ywq8-00198-00077443-00077739": "PRINCE. IF PRINCE OF SWEDEN THAT", "ceQAnn_ywq8-00199-00077739-00078439": "EVENING. SO I'M SURE YOU'RE DYING TO KNOW", "ceQAnn_ywq8-00200-00078524-00078633": "WHAT I WORE. 9 [LAUGHTER]", "ceQAnn_ywq8-00201-00078633-00078829": "AND WHAT GIGI WORE AND JEFF WORE.", "ceQAnn_ywq8-00202-00078829-00079301": "SO ON A NOBLE WEBSITE ARE INSTRUCTIONS HOW TO DRESS.", "ceQAnn_ywq8-00203-00079301-00079688": "AS YOU CAN SEE HERE. THERE IS VERY SPECIFIC INSTRUCTIONS ABOUT", "ceQAnn_ywq8-00204-00079688-00080089": "WHAT ONE SHOULD WEAR TO THE BANQUET AND TO THE CEREMONY.", "ceQAnn_ywq8-00205-00080089-00080463": "AND ONE OF THE OPTIONS IS TO WEAR YOUR NATIONAL COSTUME.", "ceQAnn_ywq8-00206-00080463-00080744": "AND SO WE DID HAVE AN OPPORTUNITY WHILE WE WERE IN", "ceQAnn_ywq8-00207-00080744-00081444": "STOCKHOLM TO WEAR OUR NATIONAL COSTUME, BUT WE DID MANAGE TO", "ceQAnn_ywq8-00208-00081502-00081913": "GET OURSELVES CLEANED UP AND A GIRLFRIEND OF MINE HERE AT NIH", "ceQAnn_ywq8-00209-00081913-00082177": "TOLD ME WHEN I SAID I WOULDN'T BE AT A MEETING THE FOLLOWING", "ceQAnn_ywq8-00210-00082177-00082601": "WEEK, I WAS GOING TO STOCKHOLM, SHE SAID I HAVE THE BEST", "ceQAnn_ywq8-00211-00082601-00083301": "GIRLFRIEND STORY EVER. MY FRIEND WON THE NOBLE PRIZE.", "ceQAnn_ywq8-00212-00084186-00084538": "CAROL? [APPLAUSE]", "ceQAnn_ywq8-00213-00084538-00085238": ">> WELL, CAN I'M SPEECHLESS. I MUST SAY I HAVE NEVER, EVER,", "ceQAnn_ywq8-00214-00085463-00085994": "HAD AN INTRODUCTION EVER BEFORE. BETWEEN THE POSTER FOR THE TALK", "ceQAnn_ywq8-00215-00085994-00086294": "WHEN I WAS A GRADUATE STUDENT WHICH BASICALLY GAVE AWAY ALL OF", "ceQAnn_ywq8-00216-00086294-00086657": "THE SCIENCE, AND THEN THE HISTORY OF THE REST OF WHAT WE", "ceQAnn_ywq8-00217-00086657-00087145": "HAVE BEEN DOING RECENTLY, I GUESS I CAN STOP AND ASK ARE", "ceQAnn_ywq8-00218-00087145-00087369": "THERE ANY QUESTIONS? [LAUGHTER]", "ceQAnn_ywq8-00219-00087369-00087543": "IT'S REALLY A PLEASURE TO BE HERE.", "ceQAnn_ywq8-00220-00087543-00087882": "TO COME BACK AND SEE, YOU KNOW, SO MANY FRIENDS.", "ceQAnn_ywq8-00221-00087882-00088405": "I HAVE A LOT OF PEOPLE I COME HERE TO THE NIH A LOT, SO I", "ceQAnn_ywq8-00222-00088405-00088775": "REALLY APPRECIATE BEING ABLE TO COME HERE FOR THIS MUCH", "ceQAnn_ywq8-00223-00088775-00089330": "POSTPONED TALK. SO WHAT I'M GOING TO DO TODAY IS", "ceQAnn_ywq8-00224-00089330-00089729": "TO GIVE JUST A LITTLE BIT OF BACKGROUND ON TELOMERs AND", "ceQAnn_ywq8-00225-00089729-00090148": "TELOMERASE. 10 THEN I'D LIKE TO TELL YOU WHAT", "ceQAnn_ywq8-00226-00090148-00090636": "WE HAVE BEEN DOING OVER THE LAST 5 OR 6 YEARS.", "ceQAnn_ywq8-00227-00090636-00090947": "AT THE VERY END, TELL YOU A NEW STORY THAT I HAVEN'T HAD A", "ceQAnn_ywq8-00228-00090947-00091389": "CHANCE TO TALK ABOUT YET. IT'S ALWAYS GOOD TO BE ABLE TO", "ceQAnn_ywq8-00229-00091389-00091737": "COME SOMEWHERE AND ACTUALLY TALK SOME SCIENCE.", "ceQAnn_ywq8-00230-00091737-00092075": "SO I'LL TELL YOU ABOUT THE TELOMERASE HISTORY AND", "ceQAnn_ywq8-00231-00092075-00092430": "DISCOVERY. JUST TO FOLLOW UP ON KATHY'S", "ceQAnn_ywq8-00232-00092430-00092906": "INTRODUCTION FROM THE NOBLE. I'LL TELL YOU A LITTLE BIT ABOUT", "ceQAnn_ywq8-00233-00092906-00093432": "THE ROLE OF SHORT TELOMERASES IN CANCER, AND THE REST OF THE TIME", "ceQAnn_ywq8-00234-00093432-00093888": "TELLING YOU ABOUT SHORT TELOMERES IN HUMAN GENETICS, AND", "ceQAnn_ywq8-00235-00093888-00094588": "DEGENERATIVE DISEASES. SO TELOMERES ARE THE ENDS OF", "ceQAnn_ywq8-00236-00094974-00095311": "CHROMOSOMES. YOU CAN SEE HERE IN THESE BLUE", "ceQAnn_ywq8-00237-00095311-00095660": "TIPS, AND THEY PROVIDE 2 REALLY ESSENTIAL FUNCTIONS.", "ceQAnn_ywq8-00238-00095660-00096037": "ONE IS THAT THEY HAVE TO PROTECT CHROMOSOME ENDS.", "ceQAnn_ywq8-00239-00096037-00096504": "THEY SERVE AS CAPS TO PROTECT THE ENDS FROM NUCLEAR ACES, FROM", "ceQAnn_ywq8-00240-00096504-00096900": "END TO END JOINING, FROM VARIOUS ROOM COMBINATION PROCESSES.", "ceQAnn_ywq8-00241-00096900-00097500": "THE SECOND FUNCTION, MAINTAIN LENGTH.", "ceQAnn_ywq8-00242-00097500-00097851": "AND THE TELOMERES ARE MADE OF SIMPLE DNA REPEATS THAT ARE", "ceQAnn_ywq8-00243-00097851-00098363": "BOUND BY SPECIFIC PROTEINS. THIS IS JUST AN ILLUSTRATION OF", "ceQAnn_ywq8-00244-00098363-00098761": "THE SIMPLE TELOMER REPEATS. THE END OF THE CHROMOSOME IS", "ceQAnn_ywq8-00245-00098761-00099091": "SINGLE STRANDED. AND TELOMER REPEATS IN MANY", "ceQAnn_ywq8-00246-00099091-00099504": "ORGANISMS ARE THE SIMPLE SEQUENCES.", "ceQAnn_ywq8-00247-00099504-00099874": "WHAT IS SHOWN HERE IS THE HUMAN AND ALL OF VERT BRATS HAVE THE", "ceQAnn_ywq8-00248-00099874-00100270": "SETTAGGG REPEATED OVER AND OVER AGAIN.", "ceQAnn_ywq8-00249-00100270-00100842": "YOU'LL SEE THE REPEAT TTGGGGG, WHICH IS THE TETRAHYMENA REPEAT.", "ceQAnn_ywq8-00250-00100842-00101250": "THEY ARE SIMILAR CONSERVED 11 REPEATED SEQUENCES.", "ceQAnn_ywq8-00251-00101250-00101654": "MOST IS DOUBLE STRANDED. ALTHOUGH THERE IS A SMALL REGION", "ceQAnn_ywq8-00252-00101654-00101966": "THAT IS SINGLE STRANDED AT THE VERY END.", "ceQAnn_ywq8-00253-00101966-00102256": "IN ORDER TO PROVIDE TELOMER FUNCTION, YOU NEED NOT ONLY THE", "ceQAnn_ywq8-00254-00102256-00102600": "TELOMER REPEATS BUT ALSO THE PROTEINS THAT BIND ALONG THE", "ceQAnn_ywq8-00255-00102600-00102841": "LENGTH OF THE DNA. THERE ARE PROTEINS THAT BIND TO", "ceQAnn_ywq8-00256-00102841-00103206": "THE DOUBLE STRANDED REGION AND PROTEINS THAT WIND TO THE SINGLE", "ceQAnn_ywq8-00257-00103206-00103533": "STRANDED REGION IN ORDER TO PROVIDE THIS PROTECTIVE", "ceQAnn_ywq8-00258-00103533-00104027": "FUNCTION. SO IT TURNS OUT THAT THE WAY", "ceQAnn_ywq8-00259-00104027-00104434": "THAT DNA REPLICATION OCCURS, THE VERY END OF THE CHROMOSOME ISN'T", "ceQAnn_ywq8-00260-00104434-00104826": "COMPLETELY REPLICATED. SO THIS IS WHAT WAS KNOWN IN THE", "ceQAnn_ywq8-00261-00104826-00105248": "1970s, JIM WATSON WROTE A PAPER ABOUT THIS PROBLEM OF", "ceQAnn_ywq8-00262-00105248-00105514": "REPLICATING THE VERY END OF THE CHROMOSOME.", "ceQAnn_ywq8-00263-00105514-00105896": "AND SO WITHOUT ANY OTHER MECHANISM, THE TELOMERES SHORTEN", "ceQAnn_ywq8-00264-00105896-00106453": "EVERY TIME CELLS DIVIDE. SO THIS WAS POSED AS A", "ceQAnn_ywq8-00265-00106453-00106891": "PARTICULAR PROBLEM BACK IN THE 1970s AND EARLY 80s.", "ceQAnn_ywq8-00266-00106891-00107250": "SO WE WERE JUST VERY CURIOUS TO FIND OUT HOW IS IT THAT", "ceQAnn_ywq8-00267-00107250-00107553": "CHROMOSOMES CAN BE MAINTAINED IF THERE IS A PROBLEM THAT EVERY", "ceQAnn_ywq8-00268-00107553-00108013": "TIME THE CELLS DIVIDE THEY SHOULD GET SHORTER AND SHORTER.", "ceQAnn_ywq8-00269-00108013-00108394": "AND SO TO SET THE STAGE ABOUT HOW PEOPLE WERE APPROACHING", "ceQAnn_ywq8-00270-00108394-00108924": "THIS, THIS IS A PAPER THAT WAS WRITTEN BY JAK AND LIZ WHO WERE", "ceQAnn_ywq8-00271-00108924-00109208": "THE CORECIPIENTS OF THE NOBLE PRIZE THIS YEAR.", "ceQAnn_ywq8-00272-00109208-00109908": "THEY FOUND A WAY TO LOOK AT THE FUNCTION OF TELOMERs.", "ceQAnn_ywq8-00273-00110065-00110409": "WE NEW WHAT IT LOOKED LIKE IN THESE SINGLE CELLED ORGANISM", "ceQAnn_ywq8-00274-00110409-00110895": "CALLED TETRAHYMENA WHERE THE SEQUENCE WAS CLEARLY DELINEATED.", "ceQAnn_ywq8-00275-00110895-00111585": "THAT WAS THE TTGGGG REPEATS. 12 THEY TOOK A CIRCULAR PLASMID", "ceQAnn_ywq8-00276-00111585-00111991": "FROM YEAST THAT HAD A MARKER, AND DELINEARIZE THAT HAD", "ceQAnn_ywq8-00277-00111991-00112365": "PLASMID, AND PUT ON TO THE END TELOMER SEQUENCES FROM", "ceQAnn_ywq8-00278-00112365-00112967": "TETRAHYMENA. WHEN THEY DID THAT, AND THEY PUT", "ceQAnn_ywq8-00279-00112967-00113308": "IT INTO YEAST, THEY FOUND OUT 2 REMARKABLE THINGS.", "ceQAnn_ywq8-00280-00113308-00113847": "FIRST OF ALL, THE TETRAHYMENA TELOMERs FUNCTIONED, PROTECTED", "ceQAnn_ywq8-00281-00113847-00114547": "THE END, AND THE CHROMOSOME DIVIDED SUCCESSFULLY AND WAS", "ceQAnn_ywq8-00282-00114567-00114766": "MAINTAINED AS A LINEAR CHROMOSOME.", "ceQAnn_ywq8-00283-00114766-00115191": "THE SECOND THING THAT THEY FOUND OUT, IN SUBSEQUENT FOLLOW UP", "ceQAnn_ywq8-00284-00115191-00115634": "PAPER WHICH [INDISCERNIBLE], IS THAT AFTER THIS LINEAR", "ceQAnn_ywq8-00285-00115634-00115861": "CHROMOSOME HAD BEEN MAINTAINED IN YEAST FOR A NUMBER OF", "ceQAnn_ywq8-00286-00115861-00116290": "DIVISIONS, THAT THERE WAS YEAST TELOMER SEQUENCES THAT WERE", "ceQAnn_ywq8-00287-00116290-00116733": "ADDED TO THE TERMI OF THESE REPEATS.", "ceQAnn_ywq8-00288-00116733-00116958": "SO THAT REALLY GOT THEIR ATTENTION.", "ceQAnn_ywq8-00289-00116958-00117658": "AND IN ORDER TO UNDERSTAND HOW IT IS THAT TELOMERS ARE", "ceQAnn_ywq8-00290-00117902-00118389": "MAINTAINED, THEY WROTE WHAT WE PROPOSE THAT TELOMERS ARE", "ceQAnn_ywq8-00291-00118389-00119089": "RESPONSIBLE FOR -- SUCH ACTIVITIES COULD BE ADDED SINGLE", "ceQAnn_ywq8-00292-00119167-00119554": "NUCLEOTIDES, ET CETERA. THIS WAS BOLD BECAUSE IT", "ceQAnn_ywq8-00293-00119554-00119847": "PROPOSED THAT THERE WAS A COMPLETELY UNKNOWN ENZYME THAT", "ceQAnn_ywq8-00294-00119847-00120201": "WOULD BE ELONGATED TELOMERs. THERE WERE OTHER HYPOTHESIS THAT", "ceQAnn_ywq8-00295-00120201-00120669": "INVOLVED OTHER MECHANISMS WHEREBY TELOMERs COULD BE", "ceQAnn_ywq8-00296-00120669-00121032": "ELONGATED. WHEN I JOINED THE BLACKBURN", "ceQAnn_ywq8-00297-00121032-00121304": "LABORATORY. I WANTED TO BE ABLE TO TEST, IS", "ceQAnn_ywq8-00298-00121304-00121873": "THERE REALLY SUCH A THING? SO WE AGAIN STARTED OFF WITH", "ceQAnn_ywq8-00299-00121873-00122228": "TETRAHYMENA, WHICH IS KNOWN TO BE IN THE BUSINESS OF BUILDING", "ceQAnn_ywq8-00300-00122228-00122584": "TELOMERs. 13 AND WHAT WE DID WAS TO USE A", "ceQAnn_ywq8-00301-00122584-00123247": "SINGLE STRANDED SEQUENCE PRIMER, A SMALL BLUE ARROW.", "ceQAnn_ywq8-00302-00123247-00123630": "AND PUT THOSE INTO EXTRACTS OF TETRAHYMENA, ALONG WITH", "ceQAnn_ywq8-00303-00123630-00124330": "RADIOACTIVE TGTP AND DTTP. WE FOUND THAT THE ACTIVITY IN", "ceQAnn_ywq8-00304-00124332-00125007": "THOSE CELL EXTRACTS WOULD ADD THE SEQUENCE, REPETITIVELY ON TO", "ceQAnn_ywq8-00305-00125007-00125541": "THE END OF THE PRIMER. THIS TELOMERASE, AS WE", "ceQAnn_ywq8-00306-00125541-00125908": "SUBSEQUENTLY NAMED IT. IS WHAT IS RESPONSIBLE FOR", "ceQAnn_ywq8-00307-00125908-00126608": "ELONGATING TELOMERS. THIS IS A 6 BASE REPEATING", "ceQAnn_ywq8-00308-00126856-00127413": "PATTERN THAT WAS EXTENDING UP TO THE TOP OF THIS SEQUENCING GEL.", "ceQAnn_ywq8-00309-00127413-00127881": "HAVING IDENTIFIED ENZYME ACTIVITY WHICH ADD THESE REPEATS", "ceQAnn_ywq8-00310-00127881-00128304": "ON TO A SUBSTRATE, THE NEXT QUESTION, OF COURSE, BECAME", "ceQAnn_ywq8-00311-00128304-00128551": "WHERE DID THE INFORMATION COME FROM?", "ceQAnn_ywq8-00312-00128551-00128878": "AND SO WE HAD VARIOUS DEBATES ABOUT IT.", "ceQAnn_ywq8-00313-00128878-00129228": "BUT WHAT WE PROPOSED THAT PERHAPS THE TELOMERASE ENZYME", "ceQAnn_ywq8-00314-00129228-00129829": "MAY CONTAIN A TEMPLATE. SURE ENOUGH, FOLLOWING UP WITH", "ceQAnn_ywq8-00315-00129829-00130347": "EXPERIMENTS, WE WERE ABLE TO SHOW THAT THERE IS AN RNA", "ceQAnn_ywq8-00316-00130347-00130681": "COMPONENT WHICH HAS THE COMPLIMENT OF THIS DNA SEQUENCE", "ceQAnn_ywq8-00317-00130681-00131080": "WITHIN THE ENZYME. SO THE TELOMERASE IS A PROTEIN", "ceQAnn_ywq8-00318-00131080-00131641": "AND RNA COMPONENT THAT ALLOWS THE SYNTHESIS OF THESE TELOMERIC", "ceQAnn_ywq8-00319-00131641-00132167": "REPEATS. YOU HAVE THE SEQUENCE HERE, AND", "ceQAnn_ywq8-00320-00132167-00132600": "THE TELOMERASE ENZYME, MADE UP OF BOTH A PROTEIN COMPONENT AS", "ceQAnn_ywq8-00321-00132600-00133001": "WELL AS AN ESSENTIAL RNA COMPONENT, WITHIN THAT IS THIS", "ceQAnn_ywq8-00322-00133001-00133299": "COMPLEMENT TO THE TELOMERIC REPEAT.", "ceQAnn_ywq8-00323-00133299-00133925": "THE TEMPLATE CAN BE USED TO FILL OUTSIDE AND MAKE MANY MANY", "ceQAnn_ywq8-00324-00133925-00134565": "COPIES OF THIS SEQUENCE. SO WE'RE VERY FASCINATED BY THE", "ceQAnn_ywq8-00325-00134565-00134977": "TELOMERASE ENZYME, HOW YOU CAN 14 HAVE AN ENZYME CARRY OUT THIS", "ceQAnn_ywq8-00326-00134977-00135466": "FUNCTION OF HAVING THE RNA COMPONENT AS PART OF THE ENZYME", "ceQAnn_ywq8-00327-00135466-00135692": "ITSELF. WE ALSO BECAME INTERESTED IN", "ceQAnn_ywq8-00328-00135692-00136004": "WHAT ACTUALLY THIS ENZYME MAY BE DOING IN CELLS.", "ceQAnn_ywq8-00329-00136004-00136617": "SO AS YOU HEARD, AFTER LEAVING THE BLACKBURN LABORATORY, I WENT", "ceQAnn_ywq8-00330-00136617-00136940": "TO [INDISCERNIBLE] WHERE I STARTED TO GET INTERESTED IN", "ceQAnn_ywq8-00331-00136940-00137371": "WHAT WAS HAPPENING IN HUMAN CELLS AT THE ENDS HAVE", "ceQAnn_ywq8-00332-00137371-00137741": "CHROMOSOMES. VERY FORTUNATELY, THERE WAS THE", "ceQAnn_ywq8-00333-00137741-00138081": "VERY BEGINNINGS OF THE GENOME MEET ACTION THAT WOULD OCCUR", "ceQAnn_ywq8-00334-00138081-00138334": "EVERY YEAR AT COLD SPRING HARBOR.", "ceQAnn_ywq8-00335-00138334-00138564": "I WAS FORTUNATE THAT I WAS AT THE MEETING WHERE THEY FIRST", "ceQAnn_ywq8-00336-00138564-00138850": "IDENTIFIED THE HUMAN TELOMERIC SEQUENCE REPEAT.", "ceQAnn_ywq8-00337-00138850-00139550": "AT THE TIME IT WASN'T KNOWN. THAT WAS PRESENTED AT A MEETING", "ceQAnn_ywq8-00338-00139661-00140078": "IN 1989. AND SO WE WERE INTERESTED THEN", "ceQAnn_ywq8-00339-00140078-00140379": "IN DOING AN EXPERIMENT TO ASK WHAT HAPPENS IN HUMAN CELLS.", "ceQAnn_ywq8-00340-00140379-00140908": "NORMAL HUMAN CELLS TO THE LENGTH OF TELOMERS, ONCE WE GOT AHEAD", "ceQAnn_ywq8-00341-00140908-00141290": "OF THE SEQUENCE, WE COULD DO A SOUTHERN BLOT.", "ceQAnn_ywq8-00342-00141290-00141875": "WHAT WE FOUND WAS THAT IN NORMAL HUMAN CELLS AS YOU PASSAGE THEM", "ceQAnn_ywq8-00343-00141875-00142165": "IN CULTURE, THEY GO CELLULAR [INDISCERNIBLE].", "ceQAnn_ywq8-00344-00142165-00142656": "THIS IS A SOUTHERN BLOT SHOWING THE SORT OF SMEAR OF THE REPEATS", "ceQAnn_ywq8-00345-00142656-00143058": "BECAUSE THE HETEROGENOUS [INDISCERNIBLE].", "ceQAnn_ywq8-00346-00143058-00143758": "THEY ARE ACTUALLY SHORTENING. SO IT TURNS OUT IN MANY PRIMARY", "ceQAnn_ywq8-00347-00143969-00144181": "HUMAN CELLS, TELOMERASE ISN'T EXPRESSED.", "ceQAnn_ywq8-00348-00144181-00144583": "SO THAT SAME PROBLEM I WAS TELLING YOU BEFORE LEADS TO SOME", "ceQAnn_ywq8-00349-00144583-00144786": "TELOMER SHORT ENTERTAINING. WE GOT -- SHORTENING.", "ceQAnn_ywq8-00350-00144786-00145308": "WE GOT VERY INTERESTED IN THIS. 15 THIS SET OF PROPOSAL TO SEE WHAT", "ceQAnn_ywq8-00351-00145308-00145781": "MIGHT HAPPEN TO CANCER CELLS WHICH HAVE TO DIVIDE, SO WE", "ceQAnn_ywq8-00352-00145781-00146231": "STARTED WALKING THE PATH OF TRYING TO UNDERSTAND THE", "ceQAnn_ywq8-00353-00146231-00146600": "FUNCTIONAL CONSEQUENCE OF TELOMER SHORTENING IN HUMAN", "ceQAnn_ywq8-00354-00146600-00147016": "CELLS. SO IN ORDER TO ASK CRITICAL", "ceQAnn_ywq8-00355-00147016-00147381": "QUESTIONS ABOUT WHAT WOULD HAPPEN IN CELLS THAT DON'T HAVE", "ceQAnn_ywq8-00356-00147381-00147847": "TELOMERASE, WE DECIDED TO USE MOUSE GENOMICS TO ASK VERY", "ceQAnn_ywq8-00357-00147847-00148426": "SPECIFIC QUESTIONS. SO TO DO THIS, WE GENERATED A", "ceQAnn_ywq8-00358-00148426-00148804": "MOUSE IN WHICH ONE OF THE 2 COPIES OF TELOMERASE WAS", "ceQAnn_ywq8-00359-00148804-00149275": "ELIMINATED. SO WHAT'S ILLUSTRATED HERE T", "ceQAnn_ywq8-00360-00149275-00149618": "NAME FOR THE GENE. THE RNA.", "ceQAnn_ywq8-00361-00149618-00149981": "THIS IS CENTRAL RNA COMPONENT OF TELOMERASE.", "ceQAnn_ywq8-00362-00149981-00150470": "AND WHAT MARIA DID IN THE LAB WAS TO GENERATE A MOUSE IN WHICH", "ceQAnn_ywq8-00363-00150470-00150938": "ONE OF THE 2 COPIES OF THE TELOMERASE RNA WAS DELETED.", "ceQAnn_ywq8-00364-00150938-00151286": "WHEN YOU CROSS 2 SUCH MICE TOGETHER, WHAT YOU GET, OF", "ceQAnn_ywq8-00365-00151286-00151729": "COURSE, IS THE WILDTYPE, THE NULL ANIMALS.", "ceQAnn_ywq8-00366-00151729-00152262": "THESE WERE PERFECTLY NORMAL WHEN THEY WERE BORN IN NORMAL RATIOS,", "ceQAnn_ywq8-00367-00152262-00152587": "BUT WE CAN SHOW THAT THIS WAS NO ENZYME ACTIVITY FOR TELOMERASE", "ceQAnn_ywq8-00368-00152587-00153068": "IN THESE NULL ANIMALS. SO WE WERE, THEN, INTERESTED IN", "ceQAnn_ywq8-00369-00153068-00153361": "WHAT HAPPENS IN FUTURE GENERATIONS.", "ceQAnn_ywq8-00370-00153361-00153801": "AND WHEN YOU TAKE 2 SUCH NULL ANIMALS TG1 FOR THE FIRST", "ceQAnn_ywq8-00371-00153801-00154210": "GENERATION. AND YOU BREED THOSE, YOU GET THE", "ceQAnn_ywq8-00372-00154210-00154487": "G2, THE SECOND GENERATIONAL ANIMALS.", "ceQAnn_ywq8-00373-00154487-00155095": "THE G3, G4, G5, ET CETERA. SO THESE MICE WERE BREEDING", "ceQAnn_ywq8-00374-00155095-00155348": "CONTINUOUSLY. WE DIDN'T SEE ANY PHENOTYPES IN", "ceQAnn_ywq8-00375-00155348-00155608": "THE EARLY GENERATIONS. 16 I'LL TELL YOU ABOUT THE ONES WE", "ceQAnn_ywq8-00376-00155608-00155889": "DID SEE IN THE LATER GENERATIONS.", "ceQAnn_ywq8-00377-00155889-00156167": "FIRST, I WANT TO SHOW YOU WHAT ACTUALLY HAPPENS TO THE", "ceQAnn_ywq8-00378-00156167-00156516": "TELOMERASES, AS THESE ANIMALS ARE BREEDING PROGRESSIVELY FOR A", "ceQAnn_ywq8-00379-00156516-00157161": "NUMBER OF GENERATIONS. SO IN ORDER TO FOLLOW THE LENGTH", "ceQAnn_ywq8-00380-00157161-00157751": "WE USED THE QUANTITATIVE ANALYSIS THAT WAS DEVELOPED.", "ceQAnn_ywq8-00381-00157751-00158040": "IT'S A METAPHASE SPREAD OF MOUSE CHROMOSOMES, WHERE THEY ARE", "ceQAnn_ywq8-00382-00158040-00158395": "STAINED IN BLUE. AND THE TELOMERASE ARE SUSTAINED", "ceQAnn_ywq8-00383-00158395-00158841": "WITH A PNA PROBE. THIS IS A VERY SHORT NUCLEOTIDE", "ceQAnn_ywq8-00384-00158841-00159142": "PROBE. THE NUMBER OF PROBES THAT CAN", "ceQAnn_ywq8-00385-00159142-00159471": "[INDISCERNIBLE] IS PROPORTIONAL TO HOW LONG IT IS.", "ceQAnn_ywq8-00386-00159471-00159877": "THE SIGNAL INTENSITY OF EACH OF THOSE DOTS IS PROPORTIONAL TO", "ceQAnn_ywq8-00387-00159877-00160439": "THE LENGTH OF THE TELOMER. YOU CAN, THEN, FOLLOW THE", "ceQAnn_ywq8-00388-00160439-00160734": "TELOMER LENGTH WITH INCREASING GENERATIONS.", "ceQAnn_ywq8-00389-00160734-00161188": "WHAT YOU GET IS WHEN YOU LOOK AT THE PARENTS HERE, THE", "ceQAnn_ywq8-00390-00161188-00161533": "HETEROZYGOUS MOUSE, THERE IS A NICE FREQUENCY DISTRIBUTION,", "ceQAnn_ywq8-00391-00161533-00161997": "THIS BEING THE LENGTH AND THE NUMBER OF ENDS THAT HAVE THAT", "ceQAnn_ywq8-00392-00161997-00162256": "LENGTH. WITH INCREASING GENERATIONS,", "ceQAnn_ywq8-00393-00162256-00162637": "THERE WAS A PROGRESSIVE SHORTENING OF THE TELOMER IN", "ceQAnn_ywq8-00394-00162637-00163304": "THESE MICE. TELOMERASE WILL MAKE IT IN VITRO", "ceQAnn_ywq8-00395-00163304-00163713": "BUT WAS SPECIAL FOR MAKING TELOMERS IN THE MOUSE.", "ceQAnn_ywq8-00396-00163713-00164129": "THE OTHER THING NICE ABOUT THIS, YOU'RE LOOKING AT THE", "ceQAnn_ywq8-00397-00164129-00164457": "CHROMOSOMES. AND WHAT WE COULD SEE IS THAT", "ceQAnn_ywq8-00398-00164457-00164825": "NOT ONLY WAS TELOMER LENGTH SHORTENING, BUT THE LOSS OF THE", "ceQAnn_ywq8-00399-00164825-00165041": "SEQUENCE WAS LEADING TO LOSS OF TELOMER FUNCTION.", "ceQAnn_ywq8-00400-00165041-00165529": "IF YOU LOOK HERE IN THE WILDTYPE 17 SPREAD YOU SEE THESE NICE MOUSE", "ceQAnn_ywq8-00401-00165529-00165839": "METAPHASE CHROMOSOMES. ALL MOUSE CHROMOSOMES ARE", "ceQAnn_ywq8-00402-00165839-00166244": "CENTRIC, THAT IS, IT'S LOCATED ALONG ONE CHROMOSOME ARM.", "ceQAnn_ywq8-00403-00166244-00166662": "YOU SEE THESE NICE BOOMER RANGES.", "ceQAnn_ywq8-00404-00166662-00167213": "WHEN YOU LOOK AT THE G2, THE G4, AND THE G6 WHAT YOU START TO SEE", "ceQAnn_ywq8-00405-00167213-00167600": "IS SOME CHROMOSOME ENDS WHERE WE DON'T DETECT ANY HYBRIDIZATION.", "ceQAnn_ywq8-00406-00167600-00167859": "SO THESE ARE THE SHORTEST IN THE POPULATION.", "ceQAnn_ywq8-00407-00167859-00168217": "THEY'VE FALLEN BELOW THE LEVEL OF DETECTABILITY OF THIS ASSAY.", "ceQAnn_ywq8-00408-00168217-00168818": "BUT THEN WE SAW SOME CHROMOSOMES THAT LOOKED LIKE THIS.", "ceQAnn_ywq8-00409-00168818-00169128": "AND THOSE ARE 2 MOUSE CHROMOSOMES THAT ARE FUSED END", "ceQAnn_ywq8-00410-00169128-00169452": "TO END. LOOKS LIKE A METACENTRIC", "ceQAnn_ywq8-00411-00169452-00169771": "CHROMOSOME. THESE ARE 2 CHROMOSOME FUSION", "ceQAnn_ywq8-00412-00169771-00170085": "EVENTS. IN ADDITION TO TELOMER SEQUENCE,", "ceQAnn_ywq8-00413-00170085-00170439": "THEY LOST FUNCTION. THEY'RE ESSENTIAL FOR PROTECTING", "ceQAnn_ywq8-00414-00170439-00171061": "CHROMOSOMES. SO THERE IS CLEARLY LOSS OF", "ceQAnn_ywq8-00415-00171061-00171496": "TELOMER FUNCTION. SO WHAT ACTUALLY HAPPENS IN THE", "ceQAnn_ywq8-00416-00171496-00171621": "MOUSE? WE SAW NO PHENOTYPES IN THE", "ceQAnn_ywq8-00417-00171621-00172014": "EARLY GENERATION MICE. BE THE MATURE GENERATION WHAT", "ceQAnn_ywq8-00418-00172014-00172482": "HAPPENS IS THAT WE SEE INCREASED APOPTOSIS, CELL DEATH OR", "ceQAnn_ywq8-00419-00172482-00172965": "CELLULAR -- AT THE LEVEL OF THE MOUSE, WHAT THAT TRANSLATES INTO", "ceQAnn_ywq8-00420-00172965-00173364": "IS THE FIRST THING WE COULD SEE WAS A DECREASE IN FERTILITY,", "ceQAnn_ywq8-00421-00173364-00174053": "THEN LATER ON INFERTILITY, BECAUSE THE TEST TEES T GERM", "ceQAnn_ywq8-00422-00174053-00174598": "CELLS WERE UNDERGOING APOPTOSIS. WE ALSO SEE APOPTOSIS IN THE", "ceQAnn_ywq8-00423-00174598-00175109": "IMMUNE SYSTEM, IN THE BNT CELLS. THERE IS A LOT OF APOPTOSIS IN", "ceQAnn_ywq8-00424-00175109-00175589": "THE INTESTINE. TISSUES THAT ARE DIVIDED ARE", "ceQAnn_ywq8-00425-00175589-00176037": "UNDERGOING APOPTOSIS. 18 SO WE, AND MANY OTHER", "ceQAnn_ywq8-00426-00176037-00176399": "LABORATORIES, ARE VERY INTERESTED IN HOW IT WOULD BE", "ceQAnn_ywq8-00427-00176399-00176796": "THAT A SHORT TELOMER WOULD CAUSE A CELL TO DIE.", "ceQAnn_ywq8-00428-00176796-00177111": "AND SO IN A SERIES OF EXPERIMENTS I WON'T HAVE TIME TO", "ceQAnn_ywq8-00429-00177111-00177622": "GET INTO, THE MODEL THAT THE FIELD HAS DEVELOPED IS THAT A", "ceQAnn_ywq8-00430-00177622-00178002": "SHORT TELOMER S INDUCE DAMAGE RESPONSE.", "ceQAnn_ywq8-00431-00178002-00178634": "IF YOU HAVE DNA AND THAT UNDERGOES A BREAK, THAT BROKEN", "ceQAnn_ywq8-00432-00178634-00178928": "REGION IS RECOGNIZED BY SPECIFIC PROTEINS.", "ceQAnn_ywq8-00433-00178928-00179311": "AND THEY WILL SIGNAL THROUGH P53 AND THE CELLS CAN UNDERGO EITHER", "ceQAnn_ywq8-00434-00179311-00180011": "APOPTOSIS OR [INDISCERNIBLE] IN THE CASE OF SHORT TELOMER, THESE", "ceQAnn_ywq8-00435-00180059-00180464": "ARE PROTECTED BY THE BINDING PROTEINS I TOLD YOU WITHOUT.", "ceQAnn_ywq8-00436-00180464-00180696": "WHEN THE TELOMERS GET TO BE -- TELOMERS GET TO BE TOO SHORT,", "ceQAnn_ywq8-00437-00180696-00181292": "THEY NO LONGER FUNCTION. AND THEY'RE RECOGNIZED BY A", "ceQAnn_ywq8-00438-00181292-00181621": "PARTICULAR SET OF PROTEINS THAT RECOGNIZES THIS AS A SHORT", "ceQAnn_ywq8-00439-00181621-00181820": "TELOMER. THIS SIGNALS THROUGH P53 AROUND", "ceQAnn_ywq8-00440-00181820-00182287": "THE CELLS UNDERGO APOPTOSIS. WE'RE INTERESTED IN", "ceQAnn_ywq8-00441-00182287-00182844": "UNDERSTANDING THAT LEAD THE SHORT TELOMERs TO INDUCE THIS", "ceQAnn_ywq8-00442-00182844-00183273": "APOPTOSIS. WE'RE INTERESTED IN THE CELLULAR", "ceQAnn_ywq8-00443-00183273-00183533": "CONSEQUENCES OF THE SHORT TELOMER.", "ceQAnn_ywq8-00444-00183533-00184194": "AS I TOLD YOU THE TELOMERASE IS ESSENTIAL FOR ALL KINDS OF CELLS", "ceQAnn_ywq8-00445-00184194-00184651": "THAT HAVE TO DIVIDE MANY TIMES. SO ONE EXAMPLE OF THAT, CANCER", "ceQAnn_ywq8-00446-00184651-00184963": "CELLS. IF YOU HAVE A PARTICULAR TISSUE,", "ceQAnn_ywq8-00447-00184963-00185455": "AND ONE CELL UNDERGOES WITH A GENETIC MUTATION THAT ALLOWS IT", "ceQAnn_ywq8-00448-00185455-00185952": "TO DIVIDE MANY MORE TIMES. YOU CAN SEE THAT THOSE CELLS ARE", "ceQAnn_ywq8-00449-00185952-00186340": "GOING TO DIVIDE RELATIVELY MANY, MANY MORE TIMES THAN THE OTHER", "ceQAnn_ywq8-00450-00186340-00186805": "CELLS WOULD DIVIDE. 19 AND WE WERE ABLE TO SHOW THAT", "ceQAnn_ywq8-00451-00186805-00187309": "THESE CANCER CELLS NEED TO HAVE TELOMERASE IN ORDER TO CONTINUE", "ceQAnn_ywq8-00452-00187309-00187917": "AND DIVIDE. THE SECOND SITUATION IS IN STEM", "ceQAnn_ywq8-00453-00187917-00188166": "CELLS, TISSUE SPECIFIC STEM CELLS WHERE YOU HAVE A", "ceQAnn_ywq8-00454-00188166-00188575": "PARTICULAR STEM CELL THAT HAS TO UNDERGO SELF-RENEWAL, BUT ALSO", "ceQAnn_ywq8-00455-00188575-00189005": "DIFFERENTIATION. THAT CELL DIVISION GIVES RISE TO", "ceQAnn_ywq8-00456-00189005-00189404": "MANY MANY DIFFERENT TYPES TO UNDERGO TISSUE RENEWAL.", "ceQAnn_ywq8-00457-00189404-00189937": "IT'S ESSENTIAL FOR THIS TISSUE RENEWAL.", "ceQAnn_ywq8-00458-00189937-00190357": "I'LL TELL YOU ONE STORY ABOUT CANCER CELLS AND THEN FOCUS THE", "ceQAnn_ywq8-00459-00190357-00190777": "REST OF THE TALK HERE ON WHAT HAPPENS WHEN YOU DON'T HAVE", "ceQAnn_ywq8-00460-00190777-00191147": "ENOUGH TELOMERASE FOR TISSUE RENEWAL.", "ceQAnn_ywq8-00461-00191147-00191451": "SO ONCE WE HAD GENERATED A TELOMERASE KNOCKOUT MOUSE, WE,", "ceQAnn_ywq8-00462-00191451-00191989": "WITH WHOM WE WERE COLLABORATING, SET OUT TO ASK WHAT IS THE ROLE", "ceQAnn_ywq8-00463-00191989-00192424": "OF SHORT TELOMERS IN THE ABILITY OFFER CANCER CELLS TO DIVIDE.", "ceQAnn_ywq8-00464-00192424-00192917": "WE CROSSED THE TELOMERASE TO A NUMBER OF MOUSE MODELS OF", "ceQAnn_ywq8-00465-00192917-00193469": "VARIOUS KINDS OF CANCER. AND THIS IS JUST A TABLE THAT", "ceQAnn_ywq8-00466-00193469-00194086": "SUMMARIZES SOME OF THE FINDING. THE EFFECTIVE SHORT TELOMERS WAS", "ceQAnn_ywq8-00467-00194086-00194556": "TO DECREASE THE RATE OF GROWTH OF THOSE TUMOR CELLS AND IN SOME", "ceQAnn_ywq8-00468-00194556-00194842": "CASES WHEN WE COULD LOOK AT THE MECHANISM, IT WAS CLEAR THAT", "ceQAnn_ywq8-00469-00194842-00195273": "APOPTOSIS WAS BEING INCREASED AND THAT WOULD, THEN, DECREASE", "ceQAnn_ywq8-00470-00195273-00195749": "THE NUMBER OF TIMES THAT THE CELLS COULD DIVIDE.", "ceQAnn_ywq8-00471-00195749-00196096": "SO WE WANTED TO FOLLOW UP ON THESE MODELS THAT SUGGESTED THAT", "ceQAnn_ywq8-00472-00196096-00196432": "SHORT TELOMERs LIMIT GROWING OF CANCER CELLS.", "ceQAnn_ywq8-00473-00196432-00196944": "WE WANTED TO LOOK AT SPECIFIC MECHANISMS AND THE PATH WAY BY", "ceQAnn_ywq8-00474-00196944-00197256": "WHICH THE SHORT TELOMERS MAY BE TRIGGERING THE CELL DEATH.", "ceQAnn_ywq8-00475-00197256-00197745": "AND SO DAVID, WHO IS A GRADUATE 20 STUDENT IN THE LAB, DECIDED TO", "ceQAnn_ywq8-00476-00197745-00198182": "USE ANOTHER MODEL OF TUMOR [INDISCERNIBLE] THAT'S THE B", "ceQAnn_ywq8-00477-00198182-00198612": "CELL MODEL IN WHICH THE [INDISCERNIBLE] -- THE ONCOGENE", "ceQAnn_ywq8-00478-00198612-00198947": "WAS DRIVEN BY THE PROMOTER IN B CELLS.", "ceQAnn_ywq8-00479-00198947-00199560": "SO WHAT HE DID WAS TO GENERATE A TRANSGENIC MOUSE AND PUT IT ON", "ceQAnn_ywq8-00480-00199560-00200024": "TO THE GENETIC BACKGROUND WITH THE HETEROZYGOUS MUTATION.", "ceQAnn_ywq8-00481-00200024-00200347": "WHEN YOU BREED THESE YOU CAN SELECT FOR THE TRANSGENIC G1", "ceQAnn_ywq8-00482-00200347-00200544": "MICE. THEN BREED THOSE.", "ceQAnn_ywq8-00483-00200544-00200895": "ALWAYS SELECTING FOR THE TRANSGENE, BREED THE ENTIRE LINE", "ceQAnn_ywq8-00484-00200895-00201247": "OF MICE DOWN LIKE THIS. AND THEN WE COULD ASK ABOUT THE", "ceQAnn_ywq8-00485-00201247-00201558": "RATES OF TUMOR FORMATION IN THE DIFFERENT LINES OF MICE.", "ceQAnn_ywq8-00486-00201558-00201991": ">> AND WHAT DAVID SAW WAS REALLY QUITE STRIKING.", "ceQAnn_ywq8-00487-00201991-00202378": "AND THAT WAS THAT THE SHORT TELOMERS REALLY LIMIT GROWTH OF", "ceQAnn_ywq8-00488-00202378-00202736": "THE TUMOR CELLS. THIS PROTECT THE MICE AND", "ceQAnn_ywq8-00489-00202736-00203023": "INCREASE THEIR SURVIVAL. SO WHAT IS SHOWN HERE, THE", "ceQAnn_ywq8-00490-00203023-00203262": "PERCENTAGE OF MICE THAT WERE ALIVE.", "ceQAnn_ywq8-00491-00203262-00203534": "AND IF YOU LOOK AT THE [INDISCERNIBLE] MICE ON THEIR", "ceQAnn_ywq8-00492-00203534-00203926": "OWN, WILDTYPE FOR TELOMERASE, SHOWN ON THE BLACK LINE, YOU CAN", "ceQAnn_ywq8-00493-00203926-00204317": "SEE THAT THE SURVIVAL IS SIGNIFICANTLY DECREASED AND BY", "ceQAnn_ywq8-00494-00204317-00204944": "100 DAYS, HALF OF THE MICE HAVE DIED OF THIS B CELL LYMPHOMA.", "ceQAnn_ywq8-00495-00204944-00205323": "WHEN YOU LOOK AT THE MICE THAT WERE THE IMMUNIC TRANSGENE AND", "ceQAnn_ywq8-00496-00205323-00205696": "NULL FOR TELOMERASE, THE FIRST GENERATION, THE LONG TELOMER", "ceQAnn_ywq8-00497-00205696-00206094": "MICE NOW, WHAT HE FOUND WAS THERE WAS NO CHANGE.", "ceQAnn_ywq8-00498-00206094-00206369": "THERE WAS A VERY SIMILAR RAPID DECLINE.", "ceQAnn_ywq8-00499-00206369-00206782": "SO THE B CELL LYMPHOMA IS GROWING VERY RAPIDLY, AND WILL", "ceQAnn_ywq8-00500-00206782-00207140": "KILL THESE MICE. 21 HOWEVER, WHEN YOU LOOK IN THE", "ceQAnn_ywq8-00501-00207140-00207512": "MICE THAT HAD THE VERY SHORT TELOMERs, YOU FIND THERE WAS A", "ceQAnn_ywq8-00502-00207512-00207848": "SIGNIFICANT PROTECTION AGAINST THE B CELL LYMPHOMAS.", "ceQAnn_ywq8-00503-00207848-00208275": "YOU CAN GO INTO THESE MICE AND LOOK AT THERE ARE VERY SMALL", "ceQAnn_ywq8-00504-00208275-00208835": "MICROLYMPHOMAS THAT START GROWING BUT THEN THEY STOP.", "ceQAnn_ywq8-00505-00208835-00209357": "SO THIS, AGAIN, MAKES THE POINT HERE THAT IT MUST BE NOT THE", "ceQAnn_ywq8-00506-00209357-00209826": "ABSENCE OF TELOMERASE BUT RATHER THE SHORT TELOMERs THAT HAVE", "ceQAnn_ywq8-00507-00209826-00210223": "TO BE CAUSING THIS EFFECT. THESE MICE ARE NULL FOR", "ceQAnn_ywq8-00508-00210223-00210562": "TELOMERASE AND THESE ARE, THE ONLY DIFFERENCE BETWEEN THIS", "ceQAnn_ywq8-00509-00210562-00210834": "COHORT AND THIS ONE IS THAT THESE HAVE SHORT TELOMERs.", "ceQAnn_ywq8-00510-00210834-00211105": "THEY HAVE BEEN BRED FOR MANY GENERATIONS.", "ceQAnn_ywq8-00511-00211105-00211708": "THE CONCLUSION, IT'S THE SHORT TELOMERs, AND LIMITING THE", "ceQAnn_ywq8-00512-00211708-00212109": "GROWTH OF THIS B CELL LYMPHOMA. ONE OF THE NICE THINGS, IT", "ceQAnn_ywq8-00513-00212109-00212526": "ALLOWS YOU TO HAVE ACCESS TO THE CELLS THAT ARE THESE PRE B CELL", "ceQAnn_ywq8-00514-00212526-00212876": "LYMPHOMAS TO ACCESS QUESTIONS ABOUT PATHWAYS.", "ceQAnn_ywq8-00515-00212876-00213502": "DAVID WANTED TO ASK WHAT HAPPENS IF YOU HAVE A SHORT TELOMER, AND", "ceQAnn_ywq8-00516-00213502-00213775": "WE KNOW THAT THAT SIGNAL IS THROUGH P53 AND THE CELLS", "ceQAnn_ywq8-00517-00213775-00214185": "UNDERGOING APOPTOSIS. WHAT HAPPENS IF YOU BLOCK APOPTOSIS?", "ceQAnn_ywq8-00518-00214185-00214696": "HE WAS ABLE TO IN THIS MODEL OVEREXPRESS THE Bcl2 ONCOGENE", "ceQAnn_ywq8-00519-00214696-00215167": "WHICH BLOCKS THE PATHWAY. TO OUR SURPRISE, WHAT WE FOUND", "ceQAnn_ywq8-00520-00215167-00215548": "IS THAT THE MICE WERE STILL PROTECTED, THE SHORT TELOMER", "ceQAnn_ywq8-00521-00215548-00215761": "UNTIL PROTECTED THE MICE AGAINST THE B CELL LYMPHOMA.", "ceQAnn_ywq8-00522-00215761-00216194": "THE YELL STOPPED GROWING. DAVID WAS ABLE TO GO ON AND SHOW", "ceQAnn_ywq8-00523-00216194-00216442": "WHEN YOU BLOCK THE APOPTOSIS THAT COMES FROM P353.", "ceQAnn_ywq8-00524-00216442-00216875": "THAT CELLULAR [INDISCERNIBLE] WILL OCCUR AND THIS WILL ALSO", "ceQAnn_ywq8-00525-00216875-00217298": "LIMIT THE TUMOR GROWTH. 22 THE TELOMERs CAN OPERATE", "ceQAnn_ywq8-00526-00217298-00217912": "THROUGH BOTH THESE PATHWAYS IN ORDER TO BLOCK THE GROWTH OF", "ceQAnn_ywq8-00527-00217912-00218439": "THESE TUMOR CELLS. SO THE SECOND PLACE WHERE", "ceQAnn_ywq8-00528-00218439-00218935": "TELOMERs ARE ESSENTIAL IN CELLS THAT HAVE TO DIVIDE IS IN", "ceQAnn_ywq8-00529-00218935-00219291": "THIS QUESTION OF TISSUE RENEWAL. AND THIS REALLY CAME TO THE", "ceQAnn_ywq8-00530-00219291-00219617": "FOREFRONT WHEN A PAPER WAS PUBLISHED IN 2001 BY", "ceQAnn_ywq8-00531-00219617-00219908": "[INDISCERNIBLE] GROUP. THIS WAS A PAPER PUBLISHED IN", "ceQAnn_ywq8-00532-00219908-00220257": "NATURE. AND IT'S ENTITLED THE RNA", "ceQAnn_ywq8-00533-00220257-00220594": "COMPONENT OF TELOMERASE IS MUTATED IN [INDISCERNIBLE]", "ceQAnn_ywq8-00534-00220594-00220983": "CONGENITA. THIS IS A GROUP IN ENGLAND WHO", "ceQAnn_ywq8-00535-00220983-00221436": "WERE DOING FAMILY STUDIES AND MAPPING GENES THAT WERE INVOLVED", "ceQAnn_ywq8-00536-00221436-00221816": "IN THIS PARTICULAR INHERITED HUMAN DISORDER.", "ceQAnn_ywq8-00537-00221816-00222191": "AND WHAT THEY FOUND WAS THAT IN THEIR MAPPING STUDIES, IT WAS", "ceQAnn_ywq8-00538-00222191-00222615": "THE RAN COMPONENT, WHICH WAS TRACKING WITH THE DISEASE IN", "ceQAnn_ywq8-00539-00222615-00222969": "THEIR FAMILIES. WHAT IS IT?", "ceQAnn_ywq8-00540-00222969-00223669": "SOME OF THE CLINICAL FEATURES, THERE ARE CRITERIA WHICH BY THE", "ceQAnn_ywq8-00541-00223696-00224017": "DISEASE GETS ITS NAME. THERE IS SKIN,", "ceQAnn_ywq8-00542-00224017-00224539": "HYPERPIGMENTATION, AND ABNORMAL GROWTH OF THE NAMES.", "ceQAnn_ywq8-00543-00224539-00224917": "BUT THE MORTALITY OF THE DISEASE WAS PRIMARILY ATTRIBUTED TO", "ceQAnn_ywq8-00544-00224917-00225348": "APPLIESIC ANEMIA OR BONE MARROW FAILURE. THERE IS ALSO A", "ceQAnn_ywq8-00545-00225348-00225719": "PULMONARY FIBROSIS, AS WELL AS INCREASED CANCER RISK WHICH", "ceQAnn_ywq8-00546-00225719-00225990": "INCREASES THE MORTALITY IN THIS DISEASE.", "ceQAnn_ywq8-00547-00225990-00226509": "OUR HYPOTHESIS GIVEN THAT THE HUMAN TELOMERASE WAS IMPLICATED", "ceQAnn_ywq8-00548-00226509-00227209": "HERE, IS THAT THE", "ceQAnn_ywq8-00549-00227707-00228075": "WE WANTED TO ASK SPECIFIC QUESTIONS ABOUT", "ceQAnn_ywq8-00550-00228075-00228359": "THIS DISEASE MODEL AND ASK WHAT IS THE ROLE OF THE SHORT", "ceQAnn_ywq8-00551-00228359-00228873": "TELOMERS. 23 THERE ARE SEVERAL MODES OF", "ceQAnn_ywq8-00552-00228873-00229573": "INHERITANCE. WHAT I WAS REFERRING TO IS THE", "ceQAnn_ywq8-00553-00229619-00230144": "[INDISCERNIBLE] PREVIOUSLY, THE GROUP HAD MAPPED THE GENE THAT", "ceQAnn_ywq8-00554-00230144-00230617": "ENCODING THE L LINKED FORM. THAT GENE THEY CALLED", "ceQAnn_ywq8-00555-00230617-00230994": "[INDISCERNIBLE]. AND IT TISSUE TURNS OUT, IT HAS", "ceQAnn_ywq8-00556-00230994-00231563": "A LINK. SO THE GROUP HAD SHOWN THE RNA", "ceQAnn_ywq8-00557-00231563-00232198": "COMPONENT IS MUTATED. AND IN WORK THAT WE HAD DONE", "ceQAnn_ywq8-00558-00232198-00232598": "BIOCHEMICALLY ON THE TELOMERASE ENZYME, WE HAD FOUND THAT THERE", "ceQAnn_ywq8-00559-00232598-00232919": "IS THIS SPECIFIC SYSTEM LOOP IN THE RNA.", "ceQAnn_ywq8-00560-00232919-00233489": "A BOX H, ACA BINDING DOMAIN, TO WHICH THIS BINDS.", "ceQAnn_ywq8-00561-00233489-00233808": "SO IT TURNS OUT THE X LINKED FORM OF THE DISEASE, YOU DON'T", "ceQAnn_ywq8-00562-00233808-00234383": "HAVE THE BINDING, YOU DESTABLIZE AND YOU GET THIS EFFECT ON", "ceQAnn_ywq8-00563-00234383-00234900": "TELOMERs. THEY SHOWED MUTATIONS IN THE RNA", "ceQAnn_ywq8-00564-00234900-00235454": "CAN LEAD TO [INDISCERNIBLE] AND I'LL SHOW YOU THAT MUTATIONS IN", "ceQAnn_ywq8-00565-00235454-00236154": "THE PROTEIN COMPONENT WHICH WE CALL TERT, ALSO LEAD TO", "ceQAnn_ywq8-00566-00236181-00236685": "DISKEROTASIS CONGENITA. WHEN A PATIENT CAME INTO THE", "ceQAnn_ywq8-00567-00236685-00237229": "CLINIC AT JOHNSON HOPKINS WITH APLASTIC ANEMIA, IT WAS APPARENT", "ceQAnn_ywq8-00568-00237229-00237589": "THIS WAS A FAMILY WITH DISKEROTASIS CONGENITA.", "ceQAnn_ywq8-00569-00237589-00238076": "THE PREVIOUS EXAMPLES WERE MAPPED TO THE RNA, AND", "ceQAnn_ywq8-00570-00238076-00238461": "[INDISCERNIBLE] AT THE TIME WAS A FELLOW IN THE LAB, AT HER OWN", "ceQAnn_ywq8-00571-00238461-00239141": "LAB AT HOPKINS, WAS ABLE TO FOLLOW THIS FAMILY AND TO STUDY", "ceQAnn_ywq8-00572-00239141-00239655": "IF INHERITANCE OF THIS DISEASE WITHIN THE FAMILY.", "ceQAnn_ywq8-00573-00239655-00239923": "AND I WANT TO MAKE A COUPLE OF POINTS FROM THIS PARTICULAR", "ceQAnn_ywq8-00574-00239923-00240392": "PEDIGREE. FIRST OF ALL, THAT THE GROUP, AS", "ceQAnn_ywq8-00575-00240392-00240760": "WELL AS [INDISCERNIBLE] SHOWED THERE IS A GENETIC ANTICIPATION", "ceQAnn_ywq8-00576-00240760-00241094": "IN THIS DISEASE. 24 THAT IS, THAT WITH EACH", "ceQAnn_ywq8-00577-00241094-00241560": "GENERATION, THERE IS AN EARLIER ONSET AND WORSENING ON", "ceQAnn_ywq8-00578-00241560-00241996": "PHENOTYPES WITHIN THIS FAMILY. AND THIS SHOULD REMIND YOU OF", "ceQAnn_ywq8-00579-00241996-00242546": "THE TELOMERASE KNOCKOUT MICE, WHERE WE SEE WORK PHENOTYPES IN", "ceQAnn_ywq8-00580-00242546-00242863": "THE LATER GENERATIONS. THE OTHER THING IS THAT THE", "ceQAnn_ywq8-00581-00242863-00243421": "EFFECTED PEOPLE ARE HETEROZYGOUS FOR MUTATIONS, EITHER THE RNA", "ceQAnn_ywq8-00582-00243421-00243709": "COMPONENT OR IN THIS PARTICULAR FAMILY IT WAS A PROTEIN", "ceQAnn_ywq8-00583-00243709-00244062": "COMPONENT WHICH WAS MUTATED. AS A GENETICIST, INTERESTED A", "ceQAnn_ywq8-00584-00244062-00244762": "LOT. THAT SUGGESTS THAT EITHER THERE", "ceQAnn_ywq8-00585-00244830-00245250": "IS A DOMINANT NEGATIVE EFFECT. SO IT COULD BE THAT IF YOU HAVE", "ceQAnn_ywq8-00586-00245250-00245701": "2 ALLYLS OF TELOMERASE T MUTANT ALLYL IS INTERACTING WITH THE", "ceQAnn_ywq8-00587-00245701-00245931": "WILDTYPE OR TAKING THAT OUT. THAT'S A DOMINANT NEGATIVE", "ceQAnn_ywq8-00588-00245931-00246313": "EFFECT. IF YOU HAVE A WILDTYPE AND IT'S", "ceQAnn_ywq8-00589-00246313-00246714": "NOT SUFFICIENT TO HAVE ONLY WILDTYPE FUNCTION, THAT'S", "ceQAnn_ywq8-00590-00246714-00246939": "[INDISCERNIBLE]. SO WE REALIZED WE WERE IN A", "ceQAnn_ywq8-00591-00246939-00247376": "SITUATION WHERE WE COULD TEST THIS VERY RIGOROUSLY, USING OUR", "ceQAnn_ywq8-00592-00247376-00247902": "TELOMERASE KNOCKOUT MOUSE. SO WE SET OUT TO ASK THE", "ceQAnn_ywq8-00593-00247902-00248359": "QUESTION WHETHER OR NOT INSUFFICIENCY WAS A MECHANISM BY", "ceQAnn_ywq8-00594-00248359-00248761": "WHICH THIS DISEASE FUNCTION WAS CARRIED OUT.", "ceQAnn_ywq8-00595-00248761-00249238": "I'LL SHOW YOU IN FACT THAT IT IS DUE TO SUFFICIENCY.", "ceQAnn_ywq8-00596-00249238-00249500": "SO THE MOUSE MODEL THAT I HAVE BEEN TELLING YOU ABOUT UP UNTIL", "ceQAnn_ywq8-00597-00249500-00249964": "NOW IS THE TELOMERASE KNOCKOUT MICE ON THE C57 BLACK 6 GENETIC", "ceQAnn_ywq8-00598-00249964-00250382": "BACKGROUND. THIS IS A SOUTHERN BLOT, BECAUSE MICE TELOMERs", "ceQAnn_ywq8-00599-00250382-00250821": "ARE VERY, VERY LONG. YOU CAN SEE THIS SMEAR, WHY WE", "ceQAnn_ywq8-00600-00250821-00251083": "QUANTITATE THEM USING THIS FISH ASSAY.", "ceQAnn_ywq8-00601-00251083-00251415": ", HOWEVER, THERE A NUMBER OF 25 SPECIES OF MICE.", "ceQAnn_ywq8-00602-00251415-00252115": "THESE WERE ALL WILDTYPE MICE. THEY WERE SIMILAR TO HUMAN", "ceQAnn_ywq8-00603-00252335-00252878": "TELOMER LENGTHS. WHAT WE DID WAS CROSS THE ALLYL", "ceQAnn_ywq8-00604-00252878-00253348": "ON TO THIS BACKGROUND HERE OF THIS CAST EI WHICH HAS HUMAN", "ceQAnn_ywq8-00605-00253348-00253638": "LIKE TELOMER LENGTHS. WE WERE DOING THAT IN ORDER TO", "ceQAnn_ywq8-00606-00253638-00253998": "DO VARIOUS OTHER STUDIES. WE RECOGNIZE THAT HAVING THESE", "ceQAnn_ywq8-00607-00253998-00254434": "MICE WITH THE KNOCKOUT ALLYL ON THE OTHER GENETIC BACKGROUND", "ceQAnn_ywq8-00608-00254434-00254646": "WOULD ALLOW US TO TEST OF QUESTION OF INSUFFICIENCY.", "ceQAnn_ywq8-00609-00254646-00255209": "SO WHAT WE WERE ABLE TO DO, THEN, IS ONCE WE HAD THIS NOW", "ceQAnn_ywq8-00610-00255209-00255786": "BACK CROSSED FOR 7 GENERATIONS ON THE BACKGROUND, IT'S NOW DO A", "ceQAnn_ywq8-00611-00255786-00256076": "CROSS LIKE WE HAD DONE BEFORE. BUT RATHER THAN FOLLOWING THE", "ceQAnn_ywq8-00612-00256076-00256685": "NULL MICE FOR PROGRESSIVE GENERATIONS, WE KEPT THE TELOMER", "ceQAnn_ywq8-00613-00256685-00256939": "HETEROZYGOUS. THIS STANDS FOR HETEROZYGOUS", "ceQAnn_ywq8-00614-00256939-00257639": "GENERATION 1, 2, 3, 4, ET CETERA.", "ceQAnn_ywq8-00615-00257667-00258228": "AND ASKED THE QUESTION WHAT HAPPENS WITH THE TELOMER LENGTH.", "ceQAnn_ywq8-00616-00258228-00258576": "WHAT WE FOUND, THERE WAS PROGRESSIVE TELOMER SHORTENING", "ceQAnn_ywq8-00617-00258576-00258979": "IN THE HETEROZYGOUS STATE. SO WHAT IS SHOWN HERE IS THIS", "ceQAnn_ywq8-00618-00258979-00259485": "QUANTITATIVE FISH ASSAY. WHILE TYPE IS SHOWN HERE IN THE", "ceQAnn_ywq8-00619-00259485-00259694": "BLACK BARS. THIS IS THE SIGNAL INTENSITY", "ceQAnn_ywq8-00620-00259694-00259862": "THESE ARE THE NUMBER OF ENDS", "ceQAnn_ywq8-00621-00259862-00260167": "THAT HAVE IT. WE'RE FOCUSING ON THE LOWER END", "ceQAnn_ywq8-00622-00260167-00260444": "OF THE DISTRIBUTION HERE. EVERYTHING ON THE UPPER END IS", "ceQAnn_ywq8-00623-00260444-00260817": "PUT INTO THIS LAST BIN WHICH IS WHY YOU SEE THIS HIGH BAR HERE.", "ceQAnn_ywq8-00624-00260817-00261517": "WHEN WE LOOK AT -- THERE", "ceQAnn_ywq8-00625-00261771-00261967": "IS PROGRESSIVE SHORTENING IN THIS", "ceQAnn_ywq8-00626-00261967-00262310": "TELOMER LENGTH DISTRIBUTION WITH INCREASING GENERATIONS, SHOWING", "ceQAnn_ywq8-00627-00262310-00263010": "THE LEVEL OF THE TELOMER LENGTH, 26 IT CAN CONTRIBUTE TO THIS", "ceQAnn_ywq8-00628-00263026-00263260": "DISEASE. NOW, OF COURSE, WHEN WE'RE", "ceQAnn_ywq8-00629-00263260-00263682": "BREEDING THESE MICE, EVERY TIME YOU BREED AND LOOK AT THE", "ceQAnn_ywq8-00630-00263682-00264217": "HETEROZYGOUS, YOU OF COURSE GET THE THE KNOCKOUT AT EACH", "ceQAnn_ywq8-00631-00264217-00264634": "DIFFERENT GENERATION. AND IN STUDYING THE COLONY OF", "ceQAnn_ywq8-00632-00264634-00265027": "MICE, WE WERE ABLE TO FIND THAT THERE IS ACTUALLY A DECREASED", "ceQAnn_ywq8-00633-00265027-00265514": "SURVIVAL DEPENDING ON WHAT GENERATION THE KNOCKOUTS CAME", "ceQAnn_ywq8-00634-00265514-00265881": "FROM. SO THIS IS A SURVIVAL CURVE.", "ceQAnn_ywq8-00635-00265881-00266068": "DAYS VERSES NUMBER OF MICE ALIVE.", "ceQAnn_ywq8-00636-00266068-00266553": "IN THE WILDTYPE, YOU CAN SEE THE COLONY IS DOING QUITE WELL.", "ceQAnn_ywq8-00637-00266553-00267153": "IF YOU LOOK AT KNOCKOUTS THAT COME FROM 3 PARENTS, THEY HAVE A", "ceQAnn_ywq8-00638-00267153-00267581": "SLIGHT DECREASE. 6 VERSES GENERATION 8 IS SHOWN", "ceQAnn_ywq8-00639-00267581-00267937": "HEAR AND HERE. THERE IS A REAL DRAMATIC", "ceQAnn_ywq8-00640-00267937-00268428": "INCREASE IN SURVIVALS A THEY ARE BRED WHEN THE PARENTS, THEN,", "ceQAnn_ywq8-00641-00268428-00268707": "HAVE SHORTER AND SHORTER TELOMERs.", "ceQAnn_ywq8-00642-00268707-00269031": "THIS INDICATES THAT THE INHERITANCE OF SHORT TELOMERs", "ceQAnn_ywq8-00643-00269031-00269374": "DECREASES THE SURVIVAL IN THESE MOUSE AND RESEMBLED THE GENETIC", "ceQAnn_ywq8-00644-00269374-00269723": "ANTICIPATION THAT'S SEEN DISKEROTASIS CONGENITA IN THIS", "ceQAnn_ywq8-00645-00269723-00270340": "HETEROZYGOUS STATE. WHEN WE'RE BREEDING THESE MICE,", "ceQAnn_ywq8-00646-00270340-00270791": "WE BREED THEM AND KNOW THE TELOMERs ARE SHORTENING.", "ceQAnn_ywq8-00647-00270791-00271078": "EVERY TIME WE DO THIS, WE GET A KNOCKOUT AS WELL AS THE", "ceQAnn_ywq8-00648-00271078-00271346": "WILDTYPE. WE WERE VERY CURIOUS TO KNOW", "ceQAnn_ywq8-00649-00271346-00271730": "WHAT HAPPENS IN THESE WILDTYPE MOUSE WHEN THEY HAVE INHERITED", "ceQAnn_ywq8-00650-00271730-00271946": "SHORT TELOMERs THROUGH MANY GENERATIONS.", "ceQAnn_ywq8-00651-00271946-00272457": "I'LL SHOW YOU THAT THESE MICE HAVE VERY SHORT TELOMERs, EVEN", "ceQAnn_ywq8-00652-00272457-00272934": "THOUGH THEY'RE WILDTYPE. 27 SO AGAIN, I'M SHOWING YOU", "ceQAnn_ywq8-00653-00272934-00273488": "REFERENCE, THE WILDTYPE LENGTHS AND THE KNOCKOUT GENERATION 1.", "ceQAnn_ywq8-00654-00273488-00273863": "I'VE ALREADY SHOWN YOU HERE IN THIS GREEN THAT THE HETEROZYGOUS", "ceQAnn_ywq8-00655-00273863-00274339": "GENERATION 5 -- IN THE BLUE, THE GENERATION 5 HAS SHORTER", "ceQAnn_ywq8-00656-00274339-00274824": "TELOMERS, SURPRISINGLY, THE WILDTYPE 5 LITTER MATES HAD", "ceQAnn_ywq8-00657-00274824-00275396": "SHORT TELOMERs. WE GET A KNOCKOUT, HETEROGENEOUS", "ceQAnn_ywq8-00658-00275396-00275848": "GENERATION 5. WE CALL THIS 5 STAR BECAUSE", "ceQAnn_ywq8-00659-00275848-00276223": "THESE MICE ARE NOT ACTUALLY WILDTYPE.", "ceQAnn_ywq8-00660-00276223-00276662": "IT'S THE SHORT TELOMERs THAT ARE CAUSING THE DISEASE IN THESE", "ceQAnn_ywq8-00661-00276662-00276906": "FAMILIES. THAT IT'S NOT THE ABSENCE OF", "ceQAnn_ywq8-00662-00276906-00277271": "TELOMERASE PER SE. SO IN THIS PARTICULAR SETTING,", "ceQAnn_ywq8-00663-00277271-00277530": "TELOMERASE IS COMPLETELY RESTORED TO WILDTYPE AND SO WE", "ceQAnn_ywq8-00664-00277530-00277979": "WERE VERY SURPRISED WHEN WE, THEN, LOOKED AT THE PHENOTYPE IN", "ceQAnn_ywq8-00665-00277979-00278411": "THESE MICE AND FOUND THAT THERE WAS A SIGNIFICANT DECREASE IN", "ceQAnn_ywq8-00666-00278411-00278885": "THE TESTEES WEIGHT AND INCREASE IN [INDISCERNIBLE].", "ceQAnn_ywq8-00667-00278885-00279443": "SO THESE NORMAL WILDTYPE MOUSE COMPARED TO 4 STAR MICE, THERE", "ceQAnn_ywq8-00668-00279443-00279848": "WAS A PHENOTYPE IN THESE MICE, AGAIN, INDICATING THAT IT'S THE", "ceQAnn_ywq8-00669-00279848-00280105": "SHORT TELOMERs THAT ARE CAUSING THE EFFECT, EVEN WHEN", "ceQAnn_ywq8-00670-00280105-00280452": "TELOMERASE IS RESTORED TO THE WILDTYPE SETTINGS.", "ceQAnn_ywq8-00671-00280452-00280904": "WE CALLED THIS GENETIC DISEASE IN THE ABSENCE OF TELOMERASE", "ceQAnn_ywq8-00672-00280904-00281273": "MUTATION OR FORM OF CULT GENETIC DISEASE. THIS IS PARTICULARLY", "ceQAnn_ywq8-00673-00281273-00281645": "IMPORTANT, BECAUSE THESE ARE THE ALLYLS THAT ARE NORMALLY MUTATED", "ceQAnn_ywq8-00674-00281645-00282134": "IN THE HUMAN INHERITED SYNDROMES.", "ceQAnn_ywq8-00675-00282134-00282497": "THIS SUGGESTS THAT IN FAMILIES WITH THIS DISEASE, THERE MAY BE", "ceQAnn_ywq8-00676-00282497-00282760": "PEOPLE WHERE YOU CAN SEQUENCE THE GENES THAT ARE CONTRIBUTING", "ceQAnn_ywq8-00677-00282760-00283060": "TO TELOMER LENGTH ALL YOU WANT, 28 BUT YOU'LL FIND THEY ARE", "ceQAnn_ywq8-00678-00283060-00283300": "WILDTYPE. IT'S THE ACTUAL TELOMERs", "ceQAnn_ywq8-00679-00283300-00283474": "THAT'S CONTRIBUTING TO THE DISEASE.", "ceQAnn_ywq8-00680-00283474-00283832": "A FORM OF HIDDEN OR A CULT GENETIC DISEASE.", "ceQAnn_ywq8-00681-00283832-00284286": "WE THINK THAT THIS IS IMPORTANT TO INFORM IN TERMS OF THE", "ceQAnn_ywq8-00682-00284286-00284629": "CLINICAL SETTING WHERE THE TELOMER LENGTH MAY BE THE THING", "ceQAnn_ywq8-00683-00284629-00285100": "THAT MATTERS. NOW, WHENEVER I SHOW THIS ABOUT", "ceQAnn_ywq8-00684-00285100-00285555": "THE WILDTYPE TELOMER LENGTHS BEING SHORTER, PEOPLE ALWAYS ASK", "ceQAnn_ywq8-00685-00285555-00285964": "ACTION YEAH, BUT WHAT WOULD HAPPEN IN THE NORMAL SETTING,", "ceQAnn_ywq8-00686-00285964-00286352": "THAT IS, CAN YOU EVER GET THESE TO BE BACK TO NORMAL WILDTYPE", "ceQAnn_ywq8-00687-00286352-00286649": "TELOMER LENGTHS. WE UNDERTOOK THIS EXPERIMENT", "ceQAnn_ywq8-00688-00286649-00286989": "WHICH TOOK OF 3 YEARS OF MOUSE BREEDING.", "ceQAnn_ywq8-00689-00286989-00287372": "WE ASKED THE QUESTION ABOUT WHETHER THE NORMAL WILDTYPE", "ceQAnn_ywq8-00690-00287372-00287670": "LENGTH EQUILIBRIUM COULD BE REESTABLISHED.", "ceQAnn_ywq8-00691-00287670-00288068": "WE TOOK THEY SEE MICE AND CROSSED THEM TO EACH OTHER.", "ceQAnn_ywq8-00692-00288068-00288466": "AND WE GOT OUT THESE WILDTYPE 5 STAR MICE THAT HAVE PHENOTYPES", "ceQAnn_ywq8-00693-00288466-00288810": "NOT ONLY IN THE TESTIS, BUT AS WELL AS THE INTESTINE AND THE", "ceQAnn_ywq8-00694-00288810-00289247": "IMMUNE SYSTEM. NOW, WE CROSSED THESE MILES TO", "ceQAnn_ywq8-00695-00289247-00289347": "EACH OTHER TO -- MICE TO EACH OTHER.", "ceQAnn_ywq8-00696-00289347-00290047": "HOW MANY GENERATIONS IN ORDER TO RESTORE THE GENETIC DETERMINED", "ceQAnn_ywq8-00697-00290152-00290676": "TELOMER. AFTER 4 GENERATIONS WE DID", "ceQAnn_ywq8-00698-00290676-00291123": "RESTORE THIS GENETICALLY DEFINED TELOMER LENGTH EQUILIBRIUM.", "ceQAnn_ywq8-00699-00291123-00291823": "HERE IS THE 4 MOUSE IN RED COMPARED TO WILDTYPE MICE IN", "ceQAnn_ywq8-00700-00291850-00292267": "BLUE. THE WILDTYPE 5 STAR T WHICH IS 2", "ceQAnn_ywq8-00701-00292267-00292647": "GENERATIONS OF BREEDING WILDTYPE MICE, TO WILDTYPE MICE, HASN'T", "ceQAnn_ywq8-00702-00292647-00293066": "GOTTEN BACK UP TO THE NORMAL 29 GENETICALLY DEFINED EQUILIBRIUM.", "ceQAnn_ywq8-00703-00293066-00293669": "WHEN WE GET TO WILDTYPE 5 STAR 4 WE HAVE OVERLAPPING TELOMER", "ceQAnn_ywq8-00704-00293669-00294091": "LENGTH DISTRIBUTIONS. THIS INDICATES THAT IT'S A SLOW", "ceQAnn_ywq8-00705-00294091-00294516": "PROCESS, THAT WE KNOW THAT TELOMERASE IS LIMITING BECAUSE", "ceQAnn_ywq8-00706-00294516-00294974": "HALF THE LEVEL OF TELOMERASE ISN'T SUFFICIENT TO MAINTAIN", "ceQAnn_ywq8-00707-00294974-00295242": "TELOMERs IN THESE INHERITED SYNDROMES.", "ceQAnn_ywq8-00708-00295242-00295650": "AGAIN, TELOMERASE IS LIMITING. IT TAKE 4 GENERATIONS OF", "ceQAnn_ywq8-00709-00295650-00296097": "BREEDING WITH WILDTYPE LEVELS TO WE ESTABLISH THE NORMAL TELOMER", "ceQAnn_ywq8-00710-00296097-00296476": "LENGTH EQUILIBRIUM. THEN WHEN WE LOOK AT WHAT", "ceQAnn_ywq8-00711-00296476-00296722": "HAPPENS WITH THE PHENOTYPES IN THESE MICE, IF YOU LOOK AT THE", "ceQAnn_ywq8-00712-00296722-00297311": "TESTIS TUBULES, I SHOWED YOU THE HETEROGENEOUS THEY HAVE THEM,", "ceQAnn_ywq8-00713-00297311-00297738": "THE WILD STAR MICE DO, BUT WHEN YOU RESTORE THE LENGTH IT COMES", "ceQAnn_ywq8-00714-00297738-00298438": "BACK TO NORMAL. THE PHENOTYPES GO TO THE TELOMER", "ceQAnn_ywq8-00715-00298590-00298950": "LENGTHS. WE HAVE BEEN VERY INTERESTED IN", "ceQAnn_ywq8-00716-00298950-00299443": "THE QUESTION OF WHAT ARE THE ROLE OH TELOMERASE IN DISEASE", "ceQAnn_ywq8-00717-00299443-00299932": "AND HOW THE TELOMERASE RNA AND THE PROTEIN COMPONENT", "ceQAnn_ywq8-00718-00299932-00300333": "CONTRIBUTES TO THIS GENETIC ANTICIPATION THAT IS SEEN IN", "ceQAnn_ywq8-00719-00300333-00300809": "THIS INHERITED SYNDROME. IN THE LAST FEW YEARS, THERE", "ceQAnn_ywq8-00720-00300809-00301297": "HAVE BEEN SUGGESTIONS FROM A NUMBER OF DIFFERENT GROUPS THAT", "ceQAnn_ywq8-00721-00301297-00301585": "INDICATE THAT THE PROTEIN COMPONENT OF TELOMERASE MAY HAVE", "ceQAnn_ywq8-00722-00301585-00302048": "ADDITIONAL ROLES BESIDES THE ELONGATION ROLE THAT I HAVE BEEN", "ceQAnn_ywq8-00723-00302048-00302300": "TALKING ABOUT. THIS COMES FROM OVEREXPRESSION", "ceQAnn_ywq8-00724-00302300-00302655": "STUDIES THAT SUGGEST THAT THIS PROTEIN COMPONENT HAS TELOMER", "ceQAnn_ywq8-00725-00302655-00303121": "LENGTH INDEPENDENT FUNCTIONS. IN ONE STUDY IT WAS FOUND THAT", "ceQAnn_ywq8-00726-00303121-00303499": "THE TERT COMPONENT REGULATES CHROMATIN AND DNA DAMAGE", "ceQAnn_ywq8-00727-00303499-00303778": "RESPONSE. 30 IN ANOTHER, IT WAS PROPOSED THAT", "ceQAnn_ywq8-00728-00303778-00304478": "OVEREXPRESSION OF TERT PROMOTES SELF PROLIFERATION.", "ceQAnn_ywq8-00729-00304526-00304991": "HERE IS ANOTHER STUDY INDICATING THAT THE OVEREXPRESSION OF TERT", "ceQAnn_ywq8-00730-00304991-00305185": "MODULATES THE SIGNALING BATH WAY.", "ceQAnn_ywq8-00731-00305185-00305584": "WE THOUGHT IT WAS IMPORTANT TO UNDERSTAND, IF THERE IS A", "ceQAnn_ywq8-00732-00305584-00305936": "SECONDARY ROLE OF TELOMERASE. IN THESE FAMILIES THAT HAVE", "ceQAnn_ywq8-00733-00305936-00306317": "MUTATIONS WE WANT TO KNOW ABOUT THE OTHER ROLES THAT TELOMERASE", "ceQAnn_ywq8-00734-00306317-00306651": "MAY PLAY THAT ARE INDEPENDENT OF TELOMER LENGTH.", "ceQAnn_ywq8-00735-00306651-00306958": "SO ALTHOUGH THESE WERE OVEREXPRESSION STUDIES, WE", "ceQAnn_ywq8-00736-00306958-00307292": "WANTED TO LOOK IN THE PROTEIN COMPONENT KNOCKOUT AND ASKED", "ceQAnn_ywq8-00737-00307292-00307683": "WHAT HAPPENED IN THAT SETTING. WOULD WE SEE DIFFERENT", "ceQAnn_ywq8-00738-00307683-00308036": "PHENOTYPES THAT WOULD HAVE TO DO WITH THE TELOMER LENGTHS,", "ceQAnn_ywq8-00739-00308036-00308410": "INDEPENDENT ROLES OF TELOMERASE. SO ONE OF THE FIRST THINGS WE", "ceQAnn_ywq8-00740-00308410-00308904": "DID WAS A GENE EXPRESSION ARRAY. AND WE ARE USING NOW HERE THE", "ceQAnn_ywq8-00741-00308904-00309221": "BLACK 6 MICE THAT HAVE VERY, VERY, VERY LONGS, WHERE WE SEE", "ceQAnn_ywq8-00742-00309221-00309921": "NO PHENOTYPE AT ALL. THIS IS SIMPLY LOOKING AT TERT", "ceQAnn_ywq8-00743-00310111-00310669": "KNOCKOUT G1 MICE GENE EXPRESSION COMPARED TO WILDTYPE.", "ceQAnn_ywq8-00744-00310669-00310991": "WHAT YOU ARE LOOKING AT IS WHAT'S CALLED A VOLCANO PLOT.", "ceQAnn_ywq8-00745-00310991-00311413": "WE ARE AVERAGING A NUMBER OF BIOLOGICAL REPLICATES.", "ceQAnn_ywq8-00746-00311413-00311924": "SO THESE ARE THE NORMAL LEVELS OF GENE EXPRESSION, AND ANYTHING", "ceQAnn_ywq8-00747-00311924-00312372": "THAT WOULD BE DIFFERENT BETWEEN THE G1 AND WILDTYPE WOULD BE", "ceQAnn_ywq8-00748-00312372-00312948": "FOUND IN THESE QUADRANTS HERE. IN BOTH THE CASE OF KNOCKING OUT", "ceQAnn_ywq8-00749-00312948-00313435": "THE RNA COMPONENT, OR KNOCKING OUT THE PROTEIN COMPONENT, WE", "ceQAnn_ywq8-00750-00313435-00313834": "FOUND NO CHANGE IN THE GENE EXPRESSION PROFILE IN THE", "ceQAnn_ywq8-00751-00313834-00314177": "KNOCKOUT SETTING. AND WE SPECIFICALLY LOOKED AT", "ceQAnn_ywq8-00752-00314177-00314423": "Wnt SIGNALING BATH WAY -- 31 PATHWAY GENES.", "ceQAnn_ywq8-00753-00314423-00314611": "THEY ARE IN HERE BUT NOT ALTERED.", "ceQAnn_ywq8-00754-00314611-00315096": "WE LOOKED AT THE DNA DAMAGE RESPONSE.", "ceQAnn_ywq8-00755-00315096-00315649": "WE TOOK MICE KNOCKED OUT FOR THE RNA OR PROTEIN COMPONENT.", "ceQAnn_ywq8-00756-00315649-00316091": "THESE ARE FIRST GENERATION MICE. AND WE EITHER DIDN'T IRRADIATE", "ceQAnn_ywq8-00757-00316091-00316641": "THEM OR WITH 5 AND LOOKED AT THE INDUCTION OF THE DNA DAMAGE", "ceQAnn_ywq8-00758-00316641-00316888": "RESPONSE. YOU CAN SEE A NICE INDUCTION OF", "ceQAnn_ywq8-00759-00316888-00317243": "THE DNA DAMAGE RESPONSE HERE. SAME THING IN THESE TERT", "ceQAnn_ywq8-00760-00317243-00317650": "KNOCKOUT MICE. WHEN WE QUANTITATED THE NUMBER", "ceQAnn_ywq8-00761-00317650-00318350": "OF -- A T OF P53 INDUCTION IN EITHER NO IRRADIATION OR THE 5", "ceQAnn_ywq8-00762-00318366-00318886": "GRAY, WE FOUND NO SIGNIFICANT CHANGES IN EITHER THE RNA", "ceQAnn_ywq8-00763-00318886-00319276": "COMPONENT KNOCKOUT OR THE PROTEIN COMPONENT KNOCKOUT.", "ceQAnn_ywq8-00764-00319276-00319590": "SO THEN WE WANTED TO ASK A LITTLE BIT MORE OF A SUBTLE", "ceQAnn_ywq8-00765-00319590-00320097": "QUESTION, WHICH WAS, IF WE DON'T SEE ANY CHANGES IN GENE", "ceQAnn_ywq8-00766-00320097-00320325": "EXPRESSION OR CHANGES IN THE DNA DAMAGE RESPONSE, MAYBE WE WOULD", "ceQAnn_ywq8-00767-00320325-00320679": "SEE SOMETHING AT THE LEVEL OF THE PHENOTYPE OF THE MOUSE.", "ceQAnn_ywq8-00768-00320679-00321227": "WE TOOK THE PROTEIN COMPONENT KNOCKOUT MICE, THIS TERT", "ceQAnn_ywq8-00769-00321227-00321736": "COMPONENT AND BACK CROSS IT ON TO THE BACKGROUND WHERE WE CAN", "ceQAnn_ywq8-00770-00321736-00322125": "SEE NICE PHENOTYPES IN THIS PARTICULAR GENETIC BACKGROUND.", "ceQAnn_ywq8-00771-00322125-00322767": "AND WE CAN LOOK, NOW, AT THE HETEROZYGOUS MICE, LOOK AT THE", "ceQAnn_ywq8-00772-00322767-00323197": "NULL MICE AS WELL. SO WE CAN COMPARE WHAT WE SEE IN", "ceQAnn_ywq8-00773-00323197-00323445": "THE RNA COMPONENT KNOCKOUT TO WHAT WE SEE IN THE PROTEIN", "ceQAnn_ywq8-00774-00323445-00323748": "COMPONENT KNOCKOUT. SO HERE IS THE RNA COMPONENT,", "ceQAnn_ywq8-00775-00323748-00324116": "AND THE PROTEIN COMPONENT. WHEN WE LOOK AT THE TELOMER", "ceQAnn_ywq8-00776-00324116-00324471": "LENGTH, AGAIN I'M SHOWING YOU HERE THE WILDTYPE TELOMER LENGTH", "ceQAnn_ywq8-00777-00324471-00324936": "VERSES RNA COMPONENT IN THE 32 FIRST GENERATION, THE WILDTYPE", "ceQAnn_ywq8-00778-00324936-00325340": "VERSES THE PROTEIN COMPONENT. THERE IS VERY SIMILAR LEVELS OF", "ceQAnn_ywq8-00779-00325340-00325733": "SHORTENING IN BOTH THE RNA AND PROTEIN COMPONENT KNOCKOUTS.", "ceQAnn_ywq8-00780-00325733-00326263": "WHEN WE ASK ABOUT INSUFFICIENCY, WE CAN LOOK AT TELOMER LENGTH IN", "ceQAnn_ywq8-00781-00326263-00326589": "THE WILDTYPE AND PROTEIN COMPONENT NULL.", "ceQAnn_ywq8-00782-00326589-00326802": "HERE IS THE WILDTYPE DISTRIBUTION.", "ceQAnn_ywq8-00783-00326802-00327313": "THE NULL, AND WHEN WE LOOK AT 2 INDEPENDENT HETEROZYGOUS, THESE", "ceQAnn_ywq8-00784-00327313-00327699": "ARE HETEROZYGOUS FOR THE PROTEIN COMPONENT.", "ceQAnn_ywq8-00785-00327699-00328399": "THE LENGTH IS INTERMEDIATE. AND WE'RE STILL EARLY DAYS IN", "ceQAnn_ywq8-00786-00328810-00329300": "REAL ANALYZING THIS COLONY THAT WE HAVE BEEN DEVELOPING FOR THE", "ceQAnn_ywq8-00787-00329300-00329526": "PAST FEW YEARS. WE CAN SEE IF WE LOOK AT", "ceQAnn_ywq8-00788-00329526-00330106": "SURVIVAL, THESE ARE THE WILDTYPE MICE SHOWN HERE, THE SURVIVAL", "ceQAnn_ywq8-00789-00330106-00330373": "CURVE IN OUR COLONY. AND WHEN YOU LOOK AT KNOCKOUTS", "ceQAnn_ywq8-00790-00330373-00330760": "FROM FIRST GENERATION FIRSTS KNOCKOUTS FROM SECOND GENERATION", "ceQAnn_ywq8-00791-00330760-00331111": "PARENTS, YOU CAN SEE THERE IS A DECREASE IN THE SURVIVAL IN", "ceQAnn_ywq8-00792-00331111-00331339": "THESE PROTEIN COMPONENT KNOCKOUTS.", "ceQAnn_ywq8-00793-00331339-00331633": "WE CAN LOOK AT SOME OF THE PHENOTYPES IN THESE MICE.", "ceQAnn_ywq8-00794-00331633-00332091": "ONE OF THE PHENOTYPES THAT WE HAVE BEEN ABLE TO LOOK AT IN", "ceQAnn_ywq8-00795-00332091-00332791": "BOTH MICE IS THE SKELETAL DEVELOPMENT, THE Wnt SIGNALING", "ceQAnn_ywq8-00796-00332795-00333283": "PATHWAY IS KNOWN TO BE INVOLVED AND IT HAS BEEN SUGGESTING THAT", "ceQAnn_ywq8-00797-00333283-00333835": "THE NUMBER OF RIBS APPARENT IN THIS KIND OF AN X-RAY MAY BE", "ceQAnn_ywq8-00798-00333835-00334209": "ALTERED IF THE Wnt SIGNALING PATHWAY IS ALTERED.", "ceQAnn_ywq8-00799-00334209-00334777": "HOWEVER, IN THE BLACK 6 CASE, LOOKING AT WILDTYPE OR THE NULL", "ceQAnn_ywq8-00800-00334777-00335247": "FOR THE TERT OR IN THE GENETIC BACKGROUND LOOKING AT WILDTYPE", "ceQAnn_ywq8-00801-00335247-00335656": "OR A NUMBER OF NULL ANIMALS WE HAVEN'T SEEN ANY DISRUPTIONS TO", "ceQAnn_ywq8-00802-00335656-00336197": "THE Wnt SIGNALING PATHWAY. 33 SO THE PATHOLOGY THAT WE DO SEE", "ceQAnn_ywq8-00803-00336197-00336466": "IN THE TERT KNOCKOUT MICE, IN THE TESTEES, WE SEE", "ceQAnn_ywq8-00804-00336466-00337015": "[INDISCERNIBLE] LIKE WE SAW IN THE RNA.", "ceQAnn_ywq8-00805-00337015-00337250": "WE SAW THE INTESTINAL EPITHELIUM.", "ceQAnn_ywq8-00806-00337250-00337600": "WE SEE ATROPHY. THERE IS SOMETHING CALLED, THIS", "ceQAnn_ywq8-00807-00337600-00337959": "IS WHEN THERE ARE BONE MARROW FAILURE, AND HEMATOPHORESIS", "ceQAnn_ywq8-00808-00337959-00338659": "STARTS HAPPENING IN THE LIVER, SPLEEN, AND OTHER ORGANS.", "ceQAnn_ywq8-00809-00338671-00339185": "SO OUR UNLESS SO FAR IS THAT THE PHENOTYPE OF THE RNA COMPONENT", "ceQAnn_ywq8-00810-00339185-00339527": "AND THE PROTEIN COMPONENT KNOCKOUT MICE IS SIMILAR,", "ceQAnn_ywq8-00811-00339527-00339902": "INDICATING THAT SHORT TELOMERs ARE THE THINGS THAT ARE CAUSING", "ceQAnn_ywq8-00812-00339902-00340127": "THESE PHENOTYPES. THIS IS IMPORTANT TO KNOW FROM", "ceQAnn_ywq8-00813-00340127-00340505": "THE CLINICAL SETTING IN TERMS OF DISEASES YOU MIGHT ANTICIPATE IN", "ceQAnn_ywq8-00814-00340505-00340940": "FAMILIES THAT HAVE THESE INHERITED MUTATIONS.", "ceQAnn_ywq8-00815-00340940-00341360": "SO NOW JUST TO FINISH UP, I JUST WANTED TO POINT OUT, MANY OF THE", "ceQAnn_ywq8-00816-00341360-00341976": "PHENOTYPES FROM THESE SYNDROMES SHARE FEATURES OF AGE RELATED", "ceQAnn_ywq8-00817-00341976-00342229": "DISEASE. I TOLD YOU ABOUT DISKEROTASIS", "ceQAnn_ywq8-00818-00342229-00342656": "CONGENITA. THERE ARE A NUDGE OF OTHER DISEASES ASSOCIATED IN", "ceQAnn_ywq8-00819-00342656-00343141": "THESE FAMILIES. SO THERE IS INHERITED BONE", "ceQAnn_ywq8-00820-00343141-00343440": "MARROW FAILURE OR FAMILIAL APLASTIC ANEMIA.", "ceQAnn_ywq8-00821-00343440-00344119": "IMMUNE SENESCENCE. THERE IS SIGNIFICANT RATE OF", "ceQAnn_ywq8-00822-00344119-00344483": "PULMONARY FINE PROCESS, LIVER CREASE, AND INCREASED CANCER", "ceQAnn_ywq8-00823-00344483-00344735": "INCIDENTS. THESE ARE ALL THINGS THAT ARE", "ceQAnn_ywq8-00824-00344735-00345435": "SEEN IN THESE FAMILIES THAT HAVE INSUFFICIENT TELOMERASE.", "ceQAnn_ywq8-00825-00345536-00345838": "WHERE YOU HAVE A PARTICULAR GENETIC DISEASE, THAT GENETIC", "ceQAnn_ywq8-00826-00345838-00346203": "DISEASE WILL GIVE YOU THE STRONGEST CASE IN TERMS OF THE", "ceQAnn_ywq8-00827-00346203-00346560": "PHENOTYPE, BUT YOU MAY FIND THAT 34 THE PACT WAYS THAT ARE DISRUPTED", "ceQAnn_ywq8-00828-00346560-00346869": "ARE PRESENT IN OTHER INDIVIDUALS.", "ceQAnn_ywq8-00829-00346869-00347240": "SO WE THINK THAT BY STUDYING THESE FAMILIES THAT HAVE", "ceQAnn_ywq8-00830-00347240-00347623": "INSUFFICIENT TELOMERASE, IT MAY TELL US ABOUT WHAT HAPPENS IN", "ceQAnn_ywq8-00831-00347623-00347969": "INDIVIDUALS THAT HAVE SHORTS, EVEN WHEN THEY HAVE -- SHORT", "ceQAnn_ywq8-00832-00347969-00348543": "TELOMERS. SHOW IT IMPLIES IT PLAYS A ROLE", "ceQAnn_ywq8-00833-00348543-00349026": "IN CERTAIN AGE RELATED DISEASES WITHOUT FRANK TELOMERASE", "ceQAnn_ywq8-00834-00349026-00349300": "MUTATIONS. THESE ARE SITUATIONS WHERE THERE", "ceQAnn_ywq8-00835-00349300-00349845": "ARE TISSUES OF HIGH TURNOVER. SO I WANT TO LEAVE YOU WITH THIS", "ceQAnn_ywq8-00836-00349845-00350358": "SLIDE HERE WHICH SHOWS THE VERY WIDE DISTRIBUTION OF TELOMER", "ceQAnn_ywq8-00837-00350358-00350757": "LENGTH IN THE HUMAN POPULATION. IT'S BEEN KNOWN FOR SOME TIME", "ceQAnn_ywq8-00838-00350757-00351261": "THE IF YOU LOOK AT TELOMER LENGTH IN HUMANS VERSES AGE, AND", "ceQAnn_ywq8-00839-00351261-00351660": "THIS IS IN TOTAL LEUKOCYTES, NORMAL WHITE BLOOD CELLS THAT IS", "ceQAnn_ywq8-00840-00351660-00352084": "THERE IS A PROGRESSIVE DECLINE IN AGE.", "ceQAnn_ywq8-00841-00352084-00352485": "THIS HAS TO DO WITH THE FACT THAT THERE IS LIMITING AMOUNT OF", "ceQAnn_ywq8-00842-00352485-00352772": "TELOMERASE IN YELLS. THE NUMBER OF CELL DIVISIONS", "ceQAnn_ywq8-00843-00352772-00353215": "THAT OCCUR OVER THE LIFETIME OF AN INDIVIDUAL OUTSTRIPS THE", "ceQAnn_ywq8-00844-00353215-00353479": "ABILITY OF THE TELOMERASE WHICH IS CLEARLY ACTIVE IN THESE", "ceQAnn_ywq8-00845-00353479-00353730": "CELLS, BUT IS NOT ENOUGH TELOMERASE.", "ceQAnn_ywq8-00846-00353730-00354430": "THE POINT I WANT TO MAKE ABOUT THIS IS THE HUGE AMOUNT OF", "ceQAnn_ywq8-00847-00354475-00355173": "RETINOPATHY IN THE -- HETEROGENEITY.", "ceQAnn_ywq8-00848-00355173-00355709": "WHAT WE ARE FOCUSING ON IS THE PARTICULAR SUBSET OF INDIVIDUALS", "ceQAnn_ywq8-00849-00355709-00356028": "WHICH MAY HAVE A VARIETY OF DIFFERENT GENETIC INPUT AS WELL", "ceQAnn_ywq8-00850-00356028-00356341": "AS ENVIRONMENTAL INPUTS, BECAUSE WE'RE TALKING ABOUT TISSUES OF", "ceQAnn_ywq8-00851-00356341-00356601": "HIGH TURN OVER. WHERE THERE IS A LOT OF CELL", "ceQAnn_ywq8-00852-00356601-00356814": "DIVISION. 35 ANY SITUATION WHERE YOU MAY HAVE", "ceQAnn_ywq8-00853-00356814-00357259": "AN INSULT, FOR INSTANCE, TO THE IMMUNE SYSTEM AND YOU HAVE TO", "ceQAnn_ywq8-00854-00357259-00357474": "DIVIDE MORE TIMES. THAT'S GOING TO CAUSE MORE", "ceQAnn_ywq8-00855-00357474-00357882": "SHORTENING. AS A COMBINED EFFECT OF BOTH THE", "ceQAnn_ywq8-00856-00357882-00358429": "GENETIC INITIAL TELOMER LENGTH AS WELL AS ENVIRONMENTAL HISTORY", "ceQAnn_ywq8-00857-00358429-00358701": "THAT MAY PUT INDIVIDUALS WITH SHORTER TELOMERs AT THAT", "ceQAnn_ywq8-00858-00358701-00359121": "HIGHER RISK FOR CERTAIN AGE ASSOCIATED DEGENERATIVE", "ceQAnn_ywq8-00859-00359121-00359500": "DISEASES. THE COMBINED EFFECT OF LENGTH", "ceQAnn_ywq8-00860-00359500-00359963": "AND ENVIRONMENTAL HISTORY COULD CONTRIBUTE TO THESE AGE RELATED", "ceQAnn_ywq8-00861-00359963-00360444": "DISEASES. SO JUST TO SUMMARIZE WHAT I'VE", "ceQAnn_ywq8-00862-00360444-00361006": "TOLD YOU, I'VE TOLD YOU THAT TELOMERASE IS ESSENTIAL FOR", "ceQAnn_ywq8-00863-00361006-00361285": "TELOMER MAINTENANCE. TELOMER SHORTENING LEADS TO SELL", "ceQAnn_ywq8-00864-00361285-00361985": "DEATH AFTER MANY CELL DIVISIONS. SHORT TELOMERs INHIBIT TUMOR", "ceQAnn_ywq8-00865-00362292-00362708": "GROWTH THROUGH APOPTOSIS, AND THIS SUGGESTS THAT TELOMERASE", "ceQAnn_ywq8-00866-00362708-00363091": "INHIBITERS MAY BE EFFECTIVE IN CERTAIN KINDS OF CANCER THERAPY.", "ceQAnn_ywq8-00867-00363091-00363561": "I'VE SHOWN YOU THAT INSUFFICIENCY FOR TELOMERASE", "ceQAnn_ywq8-00868-00363561-00364130": "CAUSES TELOMER SHORTENING. SHORT TELOMER SAID LIMIT CELL", "ceQAnn_ywq8-00869-00364130-00364425": "GROWTH, EVEN IN THE PRESENCE OF TELOMERASE.", "ceQAnn_ywq8-00870-00364425-00364875": "SHORT TELOMERs MAY LIMIT THE LONG TERM CELL DIVISION", "ceQAnn_ywq8-00871-00364875-00365528": "POTENTIAL. INHERITANCE OF SHORT TELOMERs", "ceQAnn_ywq8-00872-00365528-00365747": "CAUSES PHENOTYPE EVEN IN WILDTYPE ANIMALS.", "ceQAnn_ywq8-00873-00365747-00366092": "THESE ARE STAR OR SO-CALLED CULT GENETIC DISEASE.", "ceQAnn_ywq8-00874-00366092-00366723": "SHORT TELOMERS CAUSE TISSUE RENEWAL IN NORMAL AGING", "ceQAnn_ywq8-00875-00366723-00367423": "POPULATION. TELOMER LENGTH MAY PREDICT THE", "ceQAnn_ywq8-00876-00367440-00367731": "ONSET OF CERTAIN AGE RELATED DISEASE.", "ceQAnn_ywq8-00877-00367731-00368171": "I WANT TO GIVE CREDIT TO THE 36 PEOPLE IN MY LIFE -- YES, IN MY", "ceQAnn_ywq8-00878-00368171-00368526": "LIFE, ALSO IN MY LIFE. IN MY LAB.", "ceQAnn_ywq8-00879-00368526-00368738": "THEY'RE IN MY LIFE. WHO HAVE DONE THESE EXPERIMENTS.", "ceQAnn_ywq8-00880-00368738-00369316": "DAVID DID THE EXPERIMENTS WITH THE MICE SHOWING THE APOPTOSIS", "ceQAnn_ywq8-00881-00369316-00370016": "IN THE CANCER CELLS. MARGARET STRONG, TAMMY MORRIS,", "ceQAnn_ywq8-00882-00370145-00370621": "WORKING WITH THE MILES TO UNDERSTAND THE ROLE OF TUMOR", "ceQAnn_ywq8-00883-00370621-00370889": "DYSFUNCTION. OUR COLLABORATORS AT HOPKINS,", "ceQAnn_ywq8-00884-00370889-00371589": "[INDISCERNIBLE] AND IN PATHOLOGY TO LOOK AT THE EFFECTS OF THE", "ceQAnn_ywq8-00885-00371752-00371934": "ABSENCE OF TELOMERASE, WE COLLABORATE ARE [INDISCERNIBLE].", "ceQAnn_ywq8-00886-00371934-00372041": "SO I'LL STOP THERE. THANKS.", "ceQAnn_ywq8-00887-00372041-00372741": "[APPLAUSE] >> I'M SURE CAROL ARE", "ceQAnn_ywq8-00888-00373574-00373644": "TAKE A FEW QUESTIONS.", "ceQAnn_ywq8-00889-00373644-00374344": "WE HAVE MICROPHONES IN EACH OF THE I'LLS.", "ceQAnn_ywq8-00890-00374554-00375160": "AISLES. >> CONGRATULATIONS FOR", "ceQAnn_ywq8-00891-00375160-00375460": "PIONEERING WORK. THERE IS A DIFFERENCE IN THE", "ceQAnn_ywq8-00892-00375460-00375678": "TELOMER LENGTH IN DIFFERENT TISSUES.", "ceQAnn_ywq8-00893-00375678-00376113": "THIS IS AN ISSUE FOR THE BRAIN AND OTHER ISSUES WHERE THE", "ceQAnn_ywq8-00894-00376113-00376808": "[INDISCERNIBLE] IS LOW. >> IN SITUATIONS WHERE IT HAS", "ceQAnn_ywq8-00895-00376808-00377145": "BEEN LOOKED AT CLOSELY, IF YOU JUST LOOK AT DIFFERENT TISSUES", "ceQAnn_ywq8-00896-00377145-00377624": "YOU CAN FIND THERE ARE DIFFERENT TELOMER LENGTHS.", "ceQAnn_ywq8-00897-00377624-00378022": "OTHER QUESTION MAY BE IS THE SAME RATE OF SHORTENING.", "ceQAnn_ywq8-00898-00378022-00378291": "WE DON'T KNOW. THERE MAY NOT BE TISSUE SPECIFIC", "ceQAnn_ywq8-00899-00378291-00378991": "SHORTEN DIVISIONS. WHAT IS THE SET POINT AT WHICH A", "ceQAnn_ywq8-00900-00379002-00379225": "SHORT TELOMER CAUSES THESE PHENOTYPES.", "ceQAnn_ywq8-00901-00379225-00379388": "THESE ARE VERY IMPORTANT QUESTIONS.", "ceQAnn_ywq8-00902-00379388-00379648": "QUESTION HAVEN'T HAD A CHANCE TO GET AT. 37", "ceQAnn_ywq8-00903-00379648-00380121": "THEY WILL BE ESSENTIAL TO ASK QUESTIONS ABOUT SOME OF THESE", "ceQAnn_ywq8-00904-00380121-00380415": "DISEASE SITUATIONS. >> FOR THE SAME CELL TYPE YOU", "ceQAnn_ywq8-00905-00380415-00380682": "HAVE STEM CELL AS WELL AS DIFFERENTIATED CELLS.", "ceQAnn_ywq8-00906-00380682-00381165": "THERE ANY WAY TO SEE THE DIFFERENCE IN THOSE 2 GROUPS?", "ceQAnn_ywq8-00907-00381165-00381704": ">> FOR THE SAME CELL TYPES, SO WE HAVEN'T SPECIFICALLY TAKEN A", "ceQAnn_ywq8-00908-00381704-00382118": "STEM CELL, TO ASK DOES A STEM CELL HAVE LONGER TELOMERs THAN", "ceQAnn_ywq8-00909-00382118-00382298": "THE IMMEDIATE DIFFERENTIATION PARTNERS.", "ceQAnn_ywq8-00910-00382298-00382852": "WE LOOKED IN THE GROWTH WAY AT THE PROGRESSIVE LOSS THROUGH", "ceQAnn_ywq8-00911-00382852-00383101": "DIFFERENT GENERATIONS. ONE OF THE THINGS ABOUT THESE", "ceQAnn_ywq8-00912-00383101-00383498": "ASSAYS IS THAT THERE IS SUCH HETEROGENEITY IN TELOMERLECT.", "ceQAnn_ywq8-00913-00383498-00383850": "WHAT HAPPENS, A LITTLE BIT OF SHORTENING, LENGTHENING,", "ceQAnn_ywq8-00914-00383850-00384235": "SHORTENING. TO GET A PRECISE MEASUREMENT IS", "ceQAnn_ywq8-00915-00384235-00384426": "DIFFICULT. YOU HAVE TO HAVE FAIRLY LARGE", "ceQAnn_ywq8-00916-00384426-00384816": "DIFFERENCES TO SEE A CHANGE. >> THANK YOU.", "ceQAnn_ywq8-00917-00384816-00385516": ">> AS WE GET CLOSER TO INDUCED PLURIPOTENT STEM CELLS, HAVE YOU", "ceQAnn_ywq8-00918-00385539-00386239": "HAD A CHANCE TO LOOK AT WHAT THE TELOMERS LOOK LIKE.", "ceQAnn_ywq8-00919-00386280-00386828": "THERE A WAY AFTER THE TELOMERs HAVE UNDER GONE SHORTENING", "ceQAnn_ywq8-00920-00386828-00387270": "DURING THESE EVENTS, CAN THEY BE REELONGGATED.", "ceQAnn_ywq8-00921-00387270-00387511": ">> THERE HAVE BEEN A VERY INTERESTING QUESTION.", "ceQAnn_ywq8-00922-00387511-00387997": "THERE EVERYBODY A NUMBER OF PAPERS BUT I THINK YOU HAVE IT", "ceQAnn_ywq8-00923-00387997-00388203": "RIGHT. WHAT WILL ACTUALLY HAPPEN IF", "ceQAnn_ywq8-00924-00388203-00388702": "THEY START OFF WITH SHORTS. ONE OF THE THINGS WE FOUND IS IT", "ceQAnn_ywq8-00925-00388702-00389171": "CERTAINLY STAKES A LARGE NUMBER OF GENERATIONS TO REESTABLISH A", "ceQAnn_ywq8-00926-00389171-00389554": "WILDTYPE TELOMER LENGTH. I THINK IT'S SOMETHING PEOPLE", "ceQAnn_ywq8-00927-00389554-00389973": "SHOULD PAY ATTENTION TO. BECAUSE IF YOU START OFF WITH 38", "ceQAnn_ywq8-00928-00389973-00390197": "SOMETHING THAT HAS SHORT TELOMERS, AS SOON AS YOU PUT IT", "ceQAnn_ywq8-00929-00390197-00390844": "INTO A WILDTYPE SETTING, THAT THEY WILL BE ESTABLISHED BACK TO", "ceQAnn_ywq8-00930-00390844-00391244": "THE CORRECT LEVEL. IT'S VERY IMPORTANT THAT OVER A", "ceQAnn_ywq8-00931-00391244-00391567": "PERIOD OF TIME YOU MAY EXPECT IT TO BE REESTABLISHED WITH THE", "ceQAnn_ywq8-00932-00391567-00391870": "CORRECT EQUILIBRIUM, BUT IT WON'T BE THAT RIGHT AWAY.", "ceQAnn_ywq8-00933-00391870-00392305": "NOBODY IS REALLY TAKING A LOOK AT THE TELOMER LENGTH IN THE", "ceQAnn_ywq8-00934-00392305-00392740": "CELLS THEY'RE LOOKING AT. IT COULD BE HIGHLY VARIABLE.", "ceQAnn_ywq8-00935-00392740-00393440": ">> THANK YOU FOR A BEAUTIFUL TALK.", "ceQAnn_ywq8-00936-00393548-00393973": "I HAD -- IS THERE A POINT OF NO RETURN IN THE SHORTENING OF THE", "ceQAnn_ywq8-00937-00393973-00394077": "TELOMERs. BECAUSE THE WILDTYPE MICE YOU", "ceQAnn_ywq8-00938-00394077-00394231": "GET STILL HAVE [INDISCERNIBLE], WHICH MEANS THAT PRESENCE OF", "ceQAnn_ywq8-00939-00394231-00394539": "NORMAL LEVELS OF TELOMERASE IS NOT ENOUGH TO ASKEW THIS", "ceQAnn_ywq8-00940-00394539-00395058": "PHENOTYPE. THERE ANYTHING KNOWN ON THAT.", "ceQAnn_ywq8-00941-00395058-00395291": ">> IN THESE STUDIES, WE'RE STARTING WITH MICE THAT ARE", "ceQAnn_ywq8-00942-00395291-00395740": "ALREADY ALIVE, AT THE LEVEL WHERE THEY CAN REPRODUCE.", "ceQAnn_ywq8-00943-00395740-00396085": "CERTAINLY WHAT WE COULD EXPECT, XENA TELOMER GETS TO BE TOO", "ceQAnn_ywq8-00944-00396085-00396588": "SHORT AND SIGNALING DNA RESPONSE, THAT AT SOME POINT", "ceQAnn_ywq8-00945-00396588-00396869": "THOSE CELLS WON'T SURVIVE ANYMORE.", "ceQAnn_ywq8-00946-00396869-00397116": "WE DO KNOW THAT THERE IS A SIGNALING MECHANISM BY WHICH THE", "ceQAnn_ywq8-00947-00397116-00397451": "SHORT TELOMERs SPECIFICALLY RECRUIT TELOMERASE.", "ceQAnn_ywq8-00948-00397451-00397856": "SO THE SHORTEST GUESS REELONGATED MORE EFFICIENTLY", "ceQAnn_ywq8-00949-00397856-00398255": "THAN A MEDIUM LENGTH DOES. THERE ARE INHERENT RESCUE", "ceQAnn_ywq8-00950-00398255-00398896": "MECHANISMS BUILT IN. BUT I CAN'T REALLY ADDRESS THAT", "ceQAnn_ywq8-00951-00398896-00399203": "QUESTION BECAUSE WE'RE DEALING WITH THE ANIMALS THAT HAVE TO BE", "ceQAnn_ywq8-00952-00399203-00399526": "BREATHING IN ORDER TO DO THAT EXPERIMENT. 39", "ceQAnn_ywq8-00953-00399526-00399942": ">> THANK YOU. >> THAT WAS WONDERFUL.", "ceQAnn_ywq8-00954-00399942-00400349": "I'VE READ THAT STRESS OR DEPRESSION OR CARDIOVASCULAR", "ceQAnn_ywq8-00955-00400349-00400803": "DISEASE, LOTS OF THINGS CAN CAUSE SHORTENING.", "ceQAnn_ywq8-00956-00400803-00401277": "CAN YOU EXPAND A LITTLE ON YOUR LAST POINT YOU MADE ABOUT THERE", "ceQAnn_ywq8-00957-00401277-00401443": "IS A GENETIC STARTING POINT, AND THEN THERE IS OTHER THINGS IN", "ceQAnn_ywq8-00958-00401443-00401591": "THE ENVIRONMENT. I THINK WE MAY BE THINK OF", "ceQAnn_ywq8-00959-00401591-00402068": "ENVIRONMENT IN CERTAIN WAYS, BUT MAYBE WE SHOULD BE THINKING IN", "ceQAnn_ywq8-00960-00402068-00402484": "OTHER WAYS ABOUT ENVIRONMENT AND TELOMERs.", "ceQAnn_ywq8-00961-00402484-00403007": ">> I THINK THERE IS, YOU KNOW, A LARGE NUMBER OF THINGS THAT ONE", "ceQAnn_ywq8-00962-00403007-00403459": "CAN THINK ABOUT. WE HAVE BEEN TAKING INITIALLY", "ceQAnn_ywq8-00963-00403459-00403899": "THE GENETIC APPROACH, ASKING WHAT SORT OF DISEASES DO YOU", "ceQAnn_ywq8-00964-00403899-00404107": "SEE. WHAT DO WE SEE IN THE MICE SUE", "ceQAnn_ywq8-00965-00404107-00404301": "GET A QUESTION ABOUT CAUSE AND EFFECT.", "ceQAnn_ywq8-00966-00404301-00404723": "AND WE CAN KNOW WHETHER IT WAS THE SHORT TELOMERs THAT CAUSED", "ceQAnn_ywq8-00967-00404723-00404884": "THAT. THERE IS A LARGE LITERATURE OF", "ceQAnn_ywq8-00968-00404884-00405211": "CORRELATION OF THINGS THAT CORRELATE WITH TELOMER LENGTH.", "ceQAnn_ywq8-00969-00405211-00405544": "THINGS THAT CORRELATE ARE NOT ALWAYS CAUSATIVE.", "ceQAnn_ywq8-00970-00405544-00405984": "I THINK THAT THE DOOR IS REALLY OPEN FOR A NUMBER OF DIFFERENT", "ceQAnn_ywq8-00971-00405984-00406133": "DISEASES. BUT WE'D LIKE THE TAKE THE", "ceQAnn_ywq8-00972-00406133-00406736": "GENETIC APPROACH AND ASK THE CAUSALITY KIND OF QUESTION.", "ceQAnn_ywq8-00973-00406736-00406874": "I THINK IT'S A TIP OF THE ICEBERG.", "ceQAnn_ywq8-00974-00406874-00407403": "IF YOU THINK ABOUT THE NUMBER OF AGE RELATED DISEASES THAT MAY", "ceQAnn_ywq8-00975-00407403-00407689": "HAVE TO DO WITH TISSUE TURN OVER, I THINK THAT USING THE", "ceQAnn_ywq8-00976-00407689-00408389": "GENETIC APPROACH WILL GET US TO KNOW MORE OF THOSE DISEASES THAT", "ceQAnn_ywq8-00977-00408486-00409186": "ARE GOING TO BE ASSOCIATED WITH TELOMER SHORTENING. 40", "ceQAnn_ywq8-00978-00409322-00409679": ">> HI. ANY THOUGHTS ON WHAT THE", "ceQAnn_ywq8-00979-00409679-00409864": "MECHANISM IS THAT'S SENSING TELOMERIC EQUILIBRIUM AND WHAT'S", "ceQAnn_ywq8-00980-00409864-00410035": "GONE SO HAYWIRE. >> NO, WE DON'T, BUT WE KNOW", "ceQAnn_ywq8-00981-00410035-00410425": "IT'S THE SHORT TELOMERs, NOT THE TUMOR LENGTH.", "ceQAnn_ywq8-00982-00410425-00410817": "WE'RE ABLE TO DO A GENETIC CROSS TO BRING IN JUST A FEW SHORT", "ceQAnn_ywq8-00983-00410817-00411113": "TELOMERs, THOSE MICE HAVE THE PHENOTYPE.", "ceQAnn_ywq8-00984-00411113-00411408": "IT'S NOT RELATIVE TO AVERAGE LENGTH.", "ceQAnn_ywq8-00985-00411408-00411796": "THAT BRINGS US BACK TO THE DNA DAMAGE RESPONSE THAT THE SHORT", "ceQAnn_ywq8-00986-00411796-00412017": "TELOMERs ACTUALLY TRIGGER SOMETHING.", "ceQAnn_ywq8-00987-00412017-00412496": "IT'S NOT MEASURING -- YOU CAN IMAGINE IT WAS MEASURING BIND", "ceQAnn_ywq8-00988-00412496-00412854": "PROTEIN. THEN IT WOULD BE AVERAGE LENGTH", "ceQAnn_ywq8-00989-00412854-00413318": "THAT WOULD CAUSE THE EFFECT. WHY THE BLACK 6 MICE HAVE SUCH", "ceQAnn_ywq8-00990-00413318-00413563": "LONG TELOMERs IS A MYSTERY TO ME.", "ceQAnn_ywq8-00991-00413563-00414013": "WE LOOKED AT A NUMBER OF RECENTLY DERIVED WILD MICE.", "ceQAnn_ywq8-00992-00414013-00414713": "WE CAUGHT WILD MICE, GOT THEM FROM WWW.WILD MICE.COM.", "ceQAnn_ywq8-00993-00414858-00415558": "YOU HEAR PEOPLE SAY DON'T PAY ATTENTION TO THEM, THEIR", "ceQAnn_ywq8-00994-00415617-00416317": "TELOMERs ARE TOO LONG. THOSE LABORATORIES TEND TO USE", "ceQAnn_ywq8-00995-00416364-00416646": "THESE LONG TELOMERs. SOMEHOW THEY WERE ALLOWED TO GET", "ceQAnn_ywq8-00996-00416646-00417131": "LONG UNDER WHATEVER BREEDING CONDITIONS THEY WERE BRED UNDER.", "ceQAnn_ywq8-00997-00417131-00417542": "BUT CLEARLY THE NORMAL ESTABLISHED WILDTYPE LENGTH IS", "ceQAnn_ywq8-00998-00417542-00418096": "VERY TIGHT LENGTH. IN ORDER TO GET AT THOSE GENETIC", "ceQAnn_ywq8-00999-00418096-00418333": "COMPONENTS, IF THEY ARE GENETIC COMPONENTS, YOU NEED TO DO A", "ceQAnn_ywq8-01000-00418333-00418688": "VERY LARGE BREEDING. WE HAVEN'T BEEN ABLE TO FOLLOW", "ceQAnn_ywq8-01001-00418688-00419000": "THAT QTL ANALYSIS TO ASK ABOUT THE DIFFERENCES.", "ceQAnn_ywq8-01002-00419000-00419377": "I THINK IT WOULD BE AN INTERESTING QUESTION. 41", "ceQAnn_ywq8-01003-00419377-00419716": ">> OKAY. WELL, ONCE AGAIN, I WANT TO", "ceQAnn_ywq8-01004-00419716-00420018": "THANK CAROL AND ONE THING I FORGOT TO MENTION IN MY", "ceQAnn_ywq8-01005-00420018-00420389": "INTRODUCTION, THIS IS THE FIRST SEMINAR SINCE GETTING THE NOBEL", "ceQAnn_ywq8-01006-00420389-00420934": "PRIZE WHICH IS PRETTY SPECIAL. AS A SMALL TOKEN WE WOULD LIKE", "ceQAnn_ywq8-01007-00420934-00421384": "TO SHARE WITH HER THIS SMALL GIFT THAT WE GIVE TO EACH OF", "ceQAnn_ywq8-01008-00421384-00421621": "OTHER LECTURES EACH YEAR. KATHY, IF YOU'LL COME UP ON", "ceQAnn_ywq8-01009-00421621-00421818": "STAGE WE'RE GOING TO DO ONE PHOTO OP, AND THEN EWE ARE ALL", "ceQAnn_ywq8-01010-00421818-00421880": "DONE. [APPLAUSE]."}}, {"audio_id": "ceRAksBW8CI", "text": {}}, {"audio_id": "ceY5OyNGRaY", "text": {"ceY5OyNGRaY-00000-00000277-00000419": "Greetings, tankers.", "ceY5OyNGRaY-00001-00000456-00000758": "It’s time for Season 3 of Battle Pass.", "ceY5OyNGRaY-00002-00000815-00001310": "Once again, two new 3D Styles and two heroes await you.", "ceY5OyNGRaY-00003-00001426-00001607": "This is Nikolay Samokhin,", "ceY5OyNGRaY-00004-00001623-00001895": "the Deputy Commander of the Marine Tank Battalion.", "ceY5OyNGRaY-00005-00001980-00002414": "An experienced officer, he took part in devising a safe route for a convoy.", "ceY5OyNGRaY-00006-00002486-00002844": "Though the preparation was careful, the convoy was ambushed.", "ceY5OyNGRaY-00007-00002985-00003291": "Sensitive equipment and personnel disappeared.", "ceY5OyNGRaY-00008-00003311-00003642": "Samokhin volunteered to be the head of the rescue operation.", "ceY5OyNGRaY-00009-00003673-00004036": "Intelligence reported the equipment had been captured by local insurgents.", "ceY5OyNGRaY-00010-00004054-00004306": "There were concerns it might end up in the wrong hands.", "ceY5OyNGRaY-00011-00004384-00004567": "Assuming command of a tank platoon,", "ceY5OyNGRaY-00012-00004570-00004864": "he went to rescue his people in his IS-4.", "ceY5OyNGRaY-00013-00004923-00005311": "But Samokhin couldn't imagine how the operation would end.", "ceY5OyNGRaY-00014-00007226-00007593": "Perch, Perch, do you copy? Do you copy?", "ceY5OyNGRaY-00015-00007782-00007912": "Newt to Perch.", "ceY5OyNGRaY-00016-00008025-00008199": "Perch, respond to Newt.", "ceY5OyNGRaY-00017-00008404-00008493": "What the…", "ceY5OyNGRaY-00018-00009193-00009584": "Damn! Watch out, everyone! I'm under attack in sector C1.", "ceY5OyNGRaY-00019-00009592-00009785": "The enemy is closer than we thought.", "ceY5OyNGRaY-00020-00009789-00009895": "Do you copy?", "ceY5OyNGRaY-00021-00011404-00011600": "Where do you think you're going?", "ceY5OyNGRaY-00022-00012240-00012558": "Perch, Carp, Roach, do you copy?", "ceY5OyNGRaY-00023-00012596-00012736": "I'm coming, guys.", "ceY5OyNGRaY-00024-00013111-00013320": "Right in the top corner!", "ceY5OyNGRaY-00025-00015235-00015479": "Perch, Carp, Roach, come in!", "ceY5OyNGRaY-00026-00015525-00015705": "I'm on my way, guys! Come in!", "ceY5OyNGRaY-00027-00015864-00016090": "Damn! Damn! Damn!", "ceY5OyNGRaY-00028-00016150-00016446": "Hold up… These are not my…", "ceY5OyNGRaY-00029-00016477-00016762": "They are rebels… Who are you?", "ceY5OyNGRaY-00030-00016900-00017327": "Meet Jack Reed, the Marine commander of the T110E5.", "ceY5OyNGRaY-00031-00017388-00017735": "He was on a covert operation in the same sector as Samokhin.", "ceY5OyNGRaY-00032-00017783-00018008": "Yeah, you can't make this stuff up.", "ceY5OyNGRaY-00033-00018088-00018246": "Reed shouldn't have been there.", "ceY5OyNGRaY-00034-00018288-00018586": "He really wasn't the type to run \"silent\". Too hot-headed.", "ceY5OyNGRaY-00035-00018655-00018939": "At the very last moment, he replaced another commander.", "ceY5OyNGRaY-00036-00019024-00019394": "That morning, their platoon was sent to evacuate a classified object.", "ceY5OyNGRaY-00037-00019472-00019672": "They should have landed on a beach,", "ceY5OyNGRaY-00038-00019685-00019972": "reached the destination point without attracting attention,", "ceY5OyNGRaY-00039-00020015-00020313": "picked up the \"package,\" and returned to the extraction point.", "ceY5OyNGRaY-00040-00020341-00020668": "But the squad had been hit by a sandstorm after landing.", "ceY5OyNGRaY-00041-00020692-00020914": "And communication with command was lost.", "ceY5OyNGRaY-00042-00021035-00021295": "Base, base! This is Condor. Do you copy?", "ceY5OyNGRaY-00043-00021400-00021655": "We've been ambushed. Requesting reinforcements. Over.", "ceY5OyNGRaY-00044-00021901-00022085": "No comms, no reinforcements.", "ceY5OyNGRaY-00045-00022115-00022292": "So we're going to do this the hard way.", "ceY5OyNGRaY-00046-00022544-00022675": "He scores!", "ceY5OyNGRaY-00047-00023664-00023880": "It seems you're doing well on your own.", "ceY5OyNGRaY-00048-00023931-00024102": "I will go look for my guys.", "ceY5OyNGRaY-00049-00024341-00024675": "Just great! I'm so going to regret this.", "ceY5OyNGRaY-00050-00024702-00024814": "Hold on there!", "ceY5OyNGRaY-00051-00025704-00025915": "Darn! My hydraulics…", "ceY5OyNGRaY-00052-00026079-00026209": "I'll get you for that.", "ceY5OyNGRaY-00053-00026517-00026588": "Goal!", "ceY5OyNGRaY-00054-00026591-00026788": "Wow! Reinforcements?!", "ceY5OyNGRaY-00055-00026856-00027184": "Captain Samokhin, Marines. We'll have a chat later.", "ceY5OyNGRaY-00056-00027249-00027439": "Okaaaay, aye aye.", "ceY5OyNGRaY-00057-00027475-00027626": "Two more on the right.", "ceY5OyNGRaY-00058-00027758-00027894": "Let’s go on the attack!", "ceY5OyNGRaY-00059-00028667-00028836": "Don't let in a knuckler, goalie!", "ceY5OyNGRaY-00060-00029429-00029601": "And there's the hat trick!", "ceY5OyNGRaY-00061-00029613-00030097": "And now, soldier, what's your rank and purpose for being in this sector?", "ceY5OyNGRaY-00062-00030162-00030385": "Staff Sergeant Reed, Marine Corps…", "ceY5OyNGRaY-00063-00030471-00030581": "Wait… Hold up…", "ceY5OyNGRaY-00064-00030833-00030918": "What?", "ceY5OyNGRaY-00065-00030929-00031070": "Stay still, Samokhin.", "ceY5OyNGRaY-00066-00031276-00031572": "Staff Sergeant Reed… What are you…", "ceY5OyNGRaY-00067-00031697-00032240": "Wow! It worked! Did you see that? Ricochet off the board! Oh, yeah!", "ceY5OyNGRaY-00068-00032260-00032652": "It's time we had a serious talk, Staff Sergeant Reed.", "ceY5OyNGRaY-00069-00033435-00033848": "That's how Captain Samokhin and Staff Sergeant Reed became acquainted.", "ceY5OyNGRaY-00070-00033926-00034213": "After their serious talk, more challenges awaited them.", "ceY5OyNGRaY-00071-00034218-00034524": "I’ll tell you later, but that's another story.", "ceY5OyNGRaY-00072-00034658-00035127": "You can choose who to recruit after you complete Battle Pass Season 3.", "ceY5OyNGRaY-00073-00035358-00035571": "Good luck on the battlefield!"}}, {"audio_id": "cfoGpfJXhUQ", "text": {"cfoGpfJXhUQ-00000-00000060-00000690": "Hello everyone, my name is Franziska Bonath and I'm very happy that Gisela is with us today from", "cfoGpfJXhUQ-00001-00000690-00001302": "the University of Tübing and she is giving us an overview of what nf-core/airrflow can do.", "cfoGpfJXhUQ-00002-00001566-00002064": "Thanks Franziska for the nice introduction. I'll present nf-core/airrflow.", "cfoGpfJXhUQ-00003-00002178-00002808": "First of all I will start with defining what's the air in airrflow. Air stands for adaptive", "cfoGpfJXhUQ-00004-00002808-00003318": "immune receptor repertoire and that's the collection of membrane proteins that are found", "cfoGpfJXhUQ-00005-00003318-00004026": "on the surface of B-cells, in which case they are called BCR, and on the surface of T-cells,", "cfoGpfJXhUQ-00006-00004026-00004734": "in which case they are called TCRs or T-cell receptors. BCRs or B-cell receptors in their", "cfoGpfJXhUQ-00007-00004734-00005226": "secreted form are also called antibodies, which is a term that we are all more familiar with.", "cfoGpfJXhUQ-00008-00005334-00005760": "The main function of these receptors is to be able to recognize foreign antigens", "cfoGpfJXhUQ-00009-00005760-00006102": "that are inside the human body, which can come for example from", "cfoGpfJXhUQ-00010-00006102-00006666": "pathogens such as viruses or bacteria, and to elicit an immune response against them.", "cfoGpfJXhUQ-00011-00006780-00007470": "To be able to recognize so many different antigens from different pathogens, these receptors have", "cfoGpfJXhUQ-00012-00007470-00008070": "to have a variety of different sequences. It's estimated that in the human body at any", "cfoGpfJXhUQ-00013-00008070-00008688": "time point, there's 10 billion to 100 billion different receptor sequences of BCRs and TCRs.", "cfoGpfJXhUQ-00014-00008922-00009414": "Airr sequencing is about getting the individual sequences of these", "cfoGpfJXhUQ-00015-00009414-00009798": "B-cell and T-cell receptors and that has a variety of applications,", "cfoGpfJXhUQ-00016-00009798-00010266": "which can vary from determining the immune state of one individual at a specific point,", "cfoGpfJXhUQ-00017-00010266-00010950": "studying immune related diseases, guiding vaccine development or guiding cancer immunotherapy.", "cfoGpfJXhUQ-00018-00011082-00011760": "I'm going to talk about a bit more detail on how this diversity of the TCRs and BCRs is generated.", "cfoGpfJXhUQ-00019-00011892-00012480": "In the human genome there are different B-gene segments, D-gene segments, J-gene segments and", "cfoGpfJXhUQ-00020-00012624-00013241": "C-gene segments, that can be combined to form these TCR and BCR receptors. In case of humans", "cfoGpfJXhUQ-00021-00013241-00014141": "there's four B-gene segments, 23 D-gene segments and six J-gene segments. What happens in the", "cfoGpfJXhUQ-00022-00014141-00014952": "B-cells and T-cells is that each one segment of each kind is combined to from a productive TCR", "cfoGpfJXhUQ-00023-00014952-00015816": "or BCR receptor. That happens at the DNA level in a process called somatic recombination. It alters", "cfoGpfJXhUQ-00024-00015816-00016313": "the genome of the cells and generates this productive TCR and BCR receptors.", "cfoGpfJXhUQ-00025-00016404-00017028": "The combination of the different gene segments doesn't happen like lego blocks,", "cfoGpfJXhUQ-00026-00017028-00017622": "just attaching them next to each other, but rather in a cut-and-paste procedure. The cutting", "cfoGpfJXhUQ-00027-00017742-00018378": "position is not always exactly at the same spot and there can also be some nucleotides", "cfoGpfJXhUQ-00028-00018522-00018744": "incorporated into these junction regions,", "cfoGpfJXhUQ-00029-00018744-00019266": "so that there's extra variability that comes from this step, that is not genome encoded.", "cfoGpfJXhUQ-00030-00019470-00020016": "In the case of the B-cells or in B-cell receptor, there's even another process that generates more", "cfoGpfJXhUQ-00031-00020016-00020640": "diversity of these receptors, which happens upon antigen stimulation. That's what happened to all", "cfoGpfJXhUQ-00032-00020640-00021126": "of us, for example, when we were first in contact with the coronavirus or the coronavirus vaccine.", "cfoGpfJXhUQ-00033-00021240-00021750": "Some B-cells in the body were able to recognize the antigens in the coronavirus", "cfoGpfJXhUQ-00034-00021750-00022488": "and they were stimulated and underwent clonal expansion that is generating a lot of", "cfoGpfJXhUQ-00035-00022590-00023130": "children cells that belong to the same B-cell clone. This happens in a manner that not all", "cfoGpfJXhUQ-00036-00023130-00023658": "of these children cells have the exact same BCR receptor sequences. The process called", "cfoGpfJXhUQ-00037-00023658-00024426": "somatic hypermutation introduces mutations in these BDJ segments, so that each of the", "cfoGpfJXhUQ-00038-00024426-00025062": "children cells has a slightly different receptor sequence. This allows to generate", "cfoGpfJXhUQ-00039-00025134-00025692": "B-cell receptors and therefore antibodies, that have even higher affinity to the original antigen.", "cfoGpfJXhUQ-00040-00025968-00026538": "You've seen that there's many different processes that contribute to the diversity", "cfoGpfJXhUQ-00041-00026538-00026945": "of this TCR and BCR sequences, including somatic recombination,", "cfoGpfJXhUQ-00042-00026945-00027576": "variable junction length and in the case of the BCRs also somatic hypermutation. This means that", "cfoGpfJXhUQ-00043-00027576-00028242": "theoretically there could be more than 10 to the power of 14 possible BCR sequences.", "cfoGpfJXhUQ-00044-00028608-00029292": "How are they sequenced? Most protocols use what's called amplicon sequencing, which is", "cfoGpfJXhUQ-00045-00029292-00029964": "the targeted amplification of this gene locus and that can be done via different protocols including", "cfoGpfJXhUQ-00046-00029964-00030498": "multiplex PCR, where one is providing primers for all the kinds of different sequences that", "cfoGpfJXhUQ-00047-00030498-00031152": "can be there. Another technique is five prime race amplification protocols, which are pretty common.", "cfoGpfJXhUQ-00048-00031314-00031698": "This sequencing protocols can incorporate what's called unique", "cfoGpfJXhUQ-00049-00031698-00032244": "molecular identifiers which allow correcting for sequencing errors", "cfoGpfJXhUQ-00050-00032298-00032616": "down the line and errors introduced by the PCR amplification process.", "cfoGpfJXhUQ-00051-00032724-00033372": "Typically for sequencing, Miseq sequencers are used, because they allow for longer read lengths,", "cfoGpfJXhUQ-00052-00033372-00033750": "that covers the complete BDJ and beginning of the C region.", "cfoGpfJXhUQ-00053-00034176-00034752": "How is the bioinformatic analysis done for these kind of sequences? This typically does", "cfoGpfJXhUQ-00054-00034752-00035274": "not happen like a traditional RNA-Seq analysis and that's because mapping to a reference genome", "cfoGpfJXhUQ-00055-00035274-00035850": "is challenging in this case, due to the high diversity of these BCR and TCR sequences. Also,", "cfoGpfJXhUQ-00056-00035850-00036396": "it's a highly repetitive genome region with all of these BD and J gene segments", "cfoGpfJXhUQ-00057-00036396-00037098": "there. For this kind of analysis, specific tools are used and the reads are aligned", "cfoGpfJXhUQ-00058-00037098-00037476": "to specific reference data, also for these BCR and TCR receptors.", "cfoGpfJXhUQ-00059-00037830-00038394": "I always say luckily for us, when wanting to write a pipeline to do this kind of analysis,", "cfoGpfJXhUQ-00060-00038394-00038898": "there's already plenty of tools out there that can analyze this data. One of the better", "cfoGpfJXhUQ-00061-00038898-00039414": "well-known ones is the immcantation framework that is developed by the Kleinstein lab in", "cfoGpfJXhUQ-00062-00039414-00040056": "Yale. It's an open source toolset to analyze AIRRseq data from beginning to end. There's", "cfoGpfJXhUQ-00063-00040056-00040542": "a whole community of users already using this framework and here you can also get the details,", "cfoGpfJXhUQ-00064-00040542-00041262": "in case you want to have more information. Thanks to developing this pipeline as part", "cfoGpfJXhUQ-00065-00041262-00041934": "of the nf-core community, we gained visibility and we quickly found quite some collaborators to", "cfoGpfJXhUQ-00066-00041934-00042414": "develop the pipeline. I want to mention that this is really a community-based development effort!", "cfoGpfJXhUQ-00067-00042546-00043284": "Susanna Marquez from the immcantation lab joined early in the beginning and also David", "cfoGpfJXhUQ-00068-00043284-00044094": "Ladd from Monash University helped by adding some features. Whereas initially, Alex Peltzer,", "cfoGpfJXhUQ-00069-00044094-00044646": "when he was still at QBiC with us, Simon Heumos and myself were developing the airrflow pipeline.", "cfoGpfJXhUQ-00070-00044814-00045636": "Now to the details of the pipeline, those are the main pipeline steps. The pipeline can process both", "cfoGpfJXhUQ-00071-00045636-00046206": "bulk AIRR sequencing data and single-cell sequencing data. When starting from bulk,", "cfoGpfJXhUQ-00072-00046206-00046872": "there's first a step of quality control of the sequencing reads and sequence assembly", "cfoGpfJXhUQ-00073-00046938-00047628": "and afterwards there's a process, where the reads are aligned to the", "cfoGpfJXhUQ-00074-00047628-00048324": "references with IgBLAST. The reference data is typically employed from the IMGT", "cfoGpfJXhUQ-00075-00048450-00049224": "consortia, which provides reference data for BCR and TCR. At this step already assembled data can", "cfoGpfJXhUQ-00076-00049224-00049704": "also be provided and for single-cell data typically we start at this step.", "cfoGpfJXhUQ-00077-00049800-00050382": "Afterwards, there's a step for clonal analysis, which identifies which of the sequences of the BCR", "cfoGpfJXhUQ-00078-00050526-00051102": "belong to which B-cell clone. It assigns the individual BCR sequences and TCR sequences to", "cfoGpfJXhUQ-00079-00051102-00051576": "their specific clone and in the case of the B-cells it can also perform lineage", "cfoGpfJXhUQ-00080-00051576-00052290": "reconstruction of the whole B-cell clone. Finally there's a step for reporting, doing repertoire", "cfoGpfJXhUQ-00081-00052290-00052902": "analysis and reporting, including QC reports by MultiQC. That's the general steps of the pipeline,", "cfoGpfJXhUQ-00082-00052979-00053634": "but now if we look a bit more detailed there is a ton more processes - individual processes", "cfoGpfJXhUQ-00083-00053634-00054120": "that are part of the pipeline. I'm going to explain them a bit in more detail now.", "cfoGpfJXhUQ-00084-00054414-00055200": "Starting for the QCN sequence assembly, the pipeline supports different sequencing protocols,", "cfoGpfJXhUQ-00085-00055200-00055752": "including multiplex PCR, in which the users have to provide the B and C-primer sequences that were", "cfoGpfJXhUQ-00086-00055752-00056304": "used for the amplification, or in the case of 5' RACE, providing the C-primer and the linker", "cfoGpfJXhUQ-00087-00056358-00057210": "sequences for amplification. Both protocols are supported with and without UMI barcodes.", "cfoGpfJXhUQ-00088-00057210-00057726": "The barcodes can also be provided in different configurations. Starting from the raw sequencing", "cfoGpfJXhUQ-00089-00057726-00058410": "data, a sample sheet needs to be provided that contains sample information and the individual", "cfoGpfJXhUQ-00090-00058410-00059478": "FASTQ files for all samples. Depending on if the sequencing protocol includes UMI barcodes or not,", "cfoGpfJXhUQ-00091-00059544-00060024": "there will be some processes but they all start with quality control of the reads with FASTQ,", "cfoGpfJXhUQ-00092-00060078-00061122": "filtering the sequences by quality threshold, masking the primer sequences and if a UMI-based", "cfoGpfJXhUQ-00093-00061122-00061728": "protocol is used, then a consensus is built from all the sequences that have the same", "cfoGpfJXhUQ-00094-00061728-00062250": "UMI barcode. This way, it also allows to correct for the errors as I mentioned before.", "cfoGpfJXhUQ-00095-00062417-00063426": "There is an extra procedure, that is employed whenever it's estimated that the length of the", "cfoGpfJXhUQ-00096-00063426-00063936": "UMI barcodes will not be sufficient to cover all of the diversity of the sample and that is", "cfoGpfJXhUQ-00097-00064008-00064517": "bypassed by first clustering all the sequences by similarity and annotating the cluster ID", "cfoGpfJXhUQ-00098-00064517-00065112": "and then two different sequences with the same UMI barcode can also be distinguished this way.", "cfoGpfJXhUQ-00099-00065274-00066132": "After building the consensus, all the sequences that contain the same UMI barcode are collapsed", "cfoGpfJXhUQ-00100-00066132-00066810": "and the count, the number of sequences with the same UMI barcode, is annotated. Other metadata is", "cfoGpfJXhUQ-00101-00066810-00067284": "also annotated as well as the count of duplicate sequences with different UMI barcodes that were", "cfoGpfJXhUQ-00102-00067284-00068160": "collapsed. This can be useful for filtering. After this step there comes the VBJ assignment", "cfoGpfJXhUQ-00103-00068160-00068736": "and filtering step and here it's also possible to start with already assembled sequences,", "cfoGpfJXhUQ-00104-00068736-00069318": "that can be provided with a sample sheet and FASTA files. Typically single cell", "cfoGpfJXhUQ-00105-00069438-00070014": "sequencing data processing starts at this step, because the pipeline", "cfoGpfJXhUQ-00106-00070014-00070692": "supports directly the output from the tool 10x Genomics CellRanger multi, which provides,", "cfoGpfJXhUQ-00107-00070692-00071664": "while incorporating also TCR and VCR sequencing in the 10x Genomics sequencing procedure, the output", "cfoGpfJXhUQ-00108-00071664-00072180": "of that tool, which is the AIRR rearrangement table, thatt contains all of the sequences there.", "cfoGpfJXhUQ-00109-00072450-00073554": "This can also be directly provided to the pipeline at that step. What that step does, it aligns the", "cfoGpfJXhUQ-00110-00073554-00074298": "sequences to the IMGT reference and then assigns what exact B, D and J segments were used there.", "cfoGpfJXhUQ-00111-00074364-00074934": "In the case of the single cell data there is an option. This gene reassignment step is optional.", "cfoGpfJXhUQ-00112-00075174-00075780": "After alignment to the IMGT reference there is a number of quality filtering steps that", "cfoGpfJXhUQ-00113-00075780-00076410": "are performed. First it's checked that the locus matches exactly the V_calls. The V(D)J", "cfoGpfJXhUQ-00114-00076626-00077094": "segment assignment, that there are a minimum of 200 informative positions,", "cfoGpfJXhUQ-00115-00077094-00077484": "maximum 10% and nucleotides, that the sequences that are", "cfoGpfJXhUQ-00116-00077610-00078270": "determined are productive, that the junction region is a multiple of three amino acids. There's", "cfoGpfJXhUQ-00117-00078270-00079110": "also a possibility of removing chimeric reads, detecting contamination across samples and finally", "cfoGpfJXhUQ-00118-00079110-00080022": "collapsing duplicate sequences if there are any. Plenty of quality filters as part of the pipeline.", "cfoGpfJXhUQ-00119-00080022-00080580": "The next step is clonal analysis. In that case hierarchical clustering is used based", "cfoGpfJXhUQ-00120-00080580-00081108": "on the hamming distances between sequences. The pipeline is also able to auto-detect", "cfoGpfJXhUQ-00121-00081258-00081684": "a hamming distance threshold that can be used to determine, which sequences are part of the", "cfoGpfJXhUQ-00122-00081684-00082248": "same clone, or are part of different clones. There is also a step for lineage reconstruction of the", "cfoGpfJXhUQ-00123-00082248-00083430": "clonal lineage trees. Recently the pipeline offers to use the Enchanter tool, which is", "cfoGpfJXhUQ-00124-00083430-00084030": "developed by Susanna Marcus in immcantation. That tool provides calls to other immcantation", "cfoGpfJXhUQ-00125-00084030-00084516": "tools and also nice reports for each of these steps. I invite you to check them out here.", "cfoGpfJXhUQ-00126-00084774-00085428": "Finally, there's a repertoire analysis step. An R Markdown report is provided, that", "cfoGpfJXhUQ-00127-00085542-00086178": "summarises the repertoire analysis results for all samples. Of notice is that", "cfoGpfJXhUQ-00128-00086322-00086814": "a custom R Markdown report can also be provided, in case that the user wants to change some things", "cfoGpfJXhUQ-00129-00086814-00087558": "in this report. It's also possible to provide an R Markdown file. Other reports of this reporting", "cfoGpfJXhUQ-00130-00087558-00088308": "analysis steps is the MultiQC QC report for all samples from the grid quality control reports.", "cfoGpfJXhUQ-00131-00088530-00088908": "Here we will see an example of this repertoire analysis report.", "cfoGpfJXhUQ-00132-00089040-00089622": "First there is a summary of all the samples used for the analysis. Clonal abundance and clonal", "cfoGpfJXhUQ-00133-00089622-00090210": "diversity are reported, together with vision usage. Finally all of the tools that are used", "cfoGpfJXhUQ-00134-00090300-00090840": "as part of the pipeline and their citations are noted here, to make it really easy for", "cfoGpfJXhUQ-00135-00090840-00091188": "users of the pipeline to also cite the original tools, that are being used.", "cfoGpfJXhUQ-00136-00091548-00091902": "As you know, all documentation for nf-core/airrflow can be found on", "cfoGpfJXhUQ-00137-00091902-00092562": "the nf-core website, so check it out if you want to use it. There are also", "cfoGpfJXhUQ-00138-00092562-00093012": "some example results of the pipeline when the full tests are run on AWS.", "cfoGpfJXhUQ-00139-00093276-00093828": "What's next for this pipeline? Stay tuned for a new release that comes really soon - we hope this", "cfoGpfJXhUQ-00140-00093828-00094524": "week or the next. It will includes more quality control and reporting as part of the Enchanter", "cfoGpfJXhUQ-00141-00094524-00095034": "tool, as I have mentioned, by Susanna Marquez, as well as and code refactoring using subworkflows.", "cfoGpfJXhUQ-00142-00095244-00095880": "At this point I would like to thank all the contributors to the pipeline: Simon Heumos and", "cfoGpfJXhUQ-00143-00095880-00096408": "myself at QBiC, Alex Peltzer who was initially at QBiC but now is at Böhringer Ingelheim,", "cfoGpfJXhUQ-00144-00096474-00096978": "Susanna Marquez at the Kleinstein Lab in Yale, David Ladd at Monash University and", "cfoGpfJXhUQ-00145-00096978-00097386": "some collaborations also at the University of Tübingen, Christophe Rochel and Marcus Kovaric.", "cfoGpfJXhUQ-00146-00097452-00097782": "If you have any questions don't hesitate to join us, join the airrflow channel", "cfoGpfJXhUQ-00147-00097902-00098256": "on nf-core Slack and if you have any questions related to the immcantation", "cfoGpfJXhUQ-00148-00098256-00098610": "tools, you also have the contact emails to contact them directly.", "cfoGpfJXhUQ-00149-00098786-00099516": "(host) Thank you very much. Everyone can now unmute themselves if there are any questions.", "cfoGpfJXhUQ-00150-00099606-00100314": "Maybe I start with one, I'm curious. In what format does airrflow expect UMIs to", "cfoGpfJXhUQ-00151-00100314-00101070": "be provided? Does it have to be in a separate file or should it be in read one or in read two?", "cfoGpfJXhUQ-00152-00101214-00101478": "(answer) It supports all kinds of these configurations that you have", "cfoGpfJXhUQ-00153-00101478-00101922": "mentioned. You can provide them. It depends on your library design,", "cfoGpfJXhUQ-00154-00101922-00102533": "where the UMI barcodes are located. Sometimes they are part of the R1 and", "cfoGpfJXhUQ-00155-00102533-00103104": "R2 reads and sometimes they are part of the index reads, it can be provided in any way.", "cfoGpfJXhUQ-00156-00103385-00103782": "There are some parameters in the pipeline where you can specify where the UMI barcode is located:", "cfoGpfJXhUQ-00157-00103782-00104268": "R1 reads, R2 reads or index files, so everything is supported in that case.", "cfoGpfJXhUQ-00158-00104268-00104844": "(host) Thank you. Are there any questions from the audience?", "cfoGpfJXhUQ-00159-00105558-00106230": "It doesn't seem so. Then I would like to thank of course Gisela but also the Chan Zuckerberg", "cfoGpfJXhUQ-00160-00106230-00106806": "Initiative for funding the bytesize talks, and as usual, if you have any questions go to Slack", "cfoGpfJXhUQ-00161-00106974-00107598": "at nf-core/airrflow and ask questions there. Thanks again."}}, {"audio_id": "cg3i67apjC0", "text": {"cg3i67apjC0-00000-00000035-00000285": "- A really common complaint for patients, they come in,", "cg3i67apjC0-00001-00000285-00000488": "they have a bump anywhere on their foot.", "cg3i67apjC0-00002-00000488-00000686": "It doesn't necessarily mean it's malignant", "cg3i67apjC0-00003-00000686-00000819": "or that there's an issue with it.", "cg3i67apjC0-00004-00000819-00001047": "If you're not having any pain with it, honestly,", "cg3i67apjC0-00005-00001047-00001205": "I really wouldn't do anything about it.", "cg3i67apjC0-00006-00001205-00001482": "If you're concerned, always, come in, we will measure it,", "cg3i67apjC0-00007-00001482-00001693": "we will monitor it, put you at ease.", "cg3i67apjC0-00008-00001693-00002022": "Sometimes an MRI is indicated to see what exactly it is.", "cg3i67apjC0-00009-00002022-00002166": "A lot of times, if you press on it,", "cg3i67apjC0-00010-00002166-00002353": "it's a little fluctuant.", "cg3i67apjC0-00011-00002353-00002563": "That can be typically a ganglionic cyst.", "cg3i67apjC0-00012-00002563-00002823": "So that's something that we can easily drain in the office,", "cg3i67apjC0-00013-00002823-00002988": "and get it to calm down.", "cg3i67apjC0-00014-00002988-00003217": "But all in all, you really don't have to do anything", "cg3i67apjC0-00015-00003217-00003350": "about it unless it's painful.", "cg3i67apjC0-00016-00003350-00003465": "So just leave it alone."}}, {"audio_id": "cgJbCtRG1lY", "text": {"cgJbCtRG1lY-00000-00000134-00000578": "SCP-423 self-inserting character", "cgJbCtRG1lY-00001-00000578-00000982": "object class: safe", "cgJbCtRG1lY-00002-00001088-00001248": "Item #: SCP-423", "cgJbCtRG1lY-00003-00001248-00001605": "Object Class: Safe", "cgJbCtRG1lY-00004-00001605-00002270": "Special Containment Procedures: SCP-423 is contained in a 5 x 5 meter room containing", "cgJbCtRG1lY-00005-00002270-00002963": "three (3) 2 x 3 meter bookshelves. An incinerator is located adjacent. All personnel entering", "cgJbCtRG1lY-00006-00002963-00003409": "or leaving the room are to be searched for written material. Any written material must", "cgJbCtRG1lY-00007-00003409-00004089": "be checked for any trace of SCP-423 and then, if found clean, incinerated.", "cgJbCtRG1lY-00008-00004089-00004751": "At night, SCP-423 is to remain in a small, plain journal marked 423. Failure to remain", "cgJbCtRG1lY-00009-00004751-00005199": "in this journal at designated times will result in loss of reading material outside of scheduled", "cgJbCtRG1lY-00010-00005199-00005317": "experiments.", "cgJbCtRG1lY-00011-00005317-00006030": "Description: SCP-423 has no physical form. It appears to exist entirely within textual", "cgJbCtRG1lY-00012-00006030-00006575": "narratives. It was discovered in a used book store in ████████, Texas,", "cgJbCtRG1lY-00013-00006575-00007190": "on ████ ██, 19██, in a copy of Tom Sawyer. The book was purchased by Agent", "cgJbCtRG1lY-00014-00007190-00007534": "██████, who located it during a routine search.", "cgJbCtRG1lY-00015-00007534-00008072": "Agent ██████ brought the book back to Sector 28 as instructed. The book", "cgJbCtRG1lY-00016-00008072-00008528": "seemed perfectly normal except for the inclusion of a character named \"Fred,\" who was not known", "cgJbCtRG1lY-00017-00008528-00009081": "to exist in any other version of the story. However, it was not until it was left by a", "cgJbCtRG1lY-00018-00009081-00009682": "copy of Moby Dick that the anomalous nature of SCP-423 became clear.", "cgJbCtRG1lY-00019-00009682-00010349": "SCP-423 is able to enter textual narratives, inserting itself as a minor character. The", "cgJbCtRG1lY-00020-00010349-00010874": "details of the character vary from story to story, but it is always named \"Fred,\" or something", "cgJbCtRG1lY-00021-00010874-00011384": "similar, and its role in the story is usually minor. Physical descriptions of the character", "cgJbCtRG1lY-00022-00011384-00011929": "are rare, but it usually appears as a human male of average height and middle years. However,", "cgJbCtRG1lY-00023-00011929-00012367": "this can change depending on the nature of the narrative. He has appeared as a student", "cgJbCtRG1lY-00024-00012367-00012862": "in narratives focusing on children (and thus presumably of an appropriate age) or even", "cgJbCtRG1lY-00025-00012862-00013415": "as a non-human in narratives where humans are absent or rare. At no time is his appearance", "cgJbCtRG1lY-00026-00013415-00013727": "remarked on as being unusual by other characters.", "cgJbCtRG1lY-00027-00013727-00014386": "SCP-423 is able to move from one narrative to another voluntarily, provided the two works", "cgJbCtRG1lY-00028-00014386-00014850": "are within one (1) meter of each other. The process takes up to three minutes, depending", "cgJbCtRG1lY-00029-00014850-00015363": "on the length of the new narrative. The entire narrative changes at once, the text on all", "cgJbCtRG1lY-00030-00015363-00015918": "pages seeming to move. Occasionally, the length of the narrative changes; in these cases,", "cgJbCtRG1lY-00031-00015918-00016469": "the text grows smaller or larger to fit the page count of the book. It is only able to", "cgJbCtRG1lY-00032-00016469-00016979": "appear in physical textual narratives. It cannot enter electronic storage, or affect", "cgJbCtRG1lY-00033-00016979-00017640": "purely visual narratives. If placed in proximity to a graphic novel or other form of sequential", "cgJbCtRG1lY-00034-00017640-00018139": "art, it will change the text boxes and dialog bubbles, but will not affect the pictures.", "cgJbCtRG1lY-00035-00018139-00018688": "Similarly, illustrations in a textual narrative do not change, even if they no longer match", "cgJbCtRG1lY-00036-00018688-00019123": "up to the narrative as affected by SCP-423.", "cgJbCtRG1lY-00037-00019123-00019657": "It prefers fictional narratives. However, it can enter any narrative that has characters,", "cgJbCtRG1lY-00038-00019657-00020229": "including anecdotes, biographies, and research notes (See Addendum 423-1).", "cgJbCtRG1lY-00039-00020229-00020800": "It can re-enter a narrative that it has already exited. If it does so, the new narrative typically", "cgJbCtRG1lY-00040-00020800-00021424": "differs from the last time SCP-423 entered the story. However, it has displayed a preference", "cgJbCtRG1lY-00041-00021424-00021718": "for narratives it has not yet entered.", "cgJbCtRG1lY-00042-00021718-00022204": "It is currently unknown what effect dying in a narrative would have on SCP-423, despite", "cgJbCtRG1lY-00043-00022204-00022829": "the best effort of researchers. SCP-423 displays a strong grasp of narrative principles, and", "cgJbCtRG1lY-00044-00022829-00023304": "is usually able to predict the best response in a given circumstance to avoid danger to", "cgJbCtRG1lY-00045-00023304-00023901": "itself. It has, however, displayed minor injuries. However, these seem to vanish when it enters", "cgJbCtRG1lY-00046-00023901-00024025": "a new narrative.", "cgJbCtRG1lY-00047-00024025-00024643": "SCP-423 can be communicated with by coaxing it into a journal. It responds to questions", "cgJbCtRG1lY-00048-00024643-00025265": "written within, with SCP-423's responses appearing underneath the questions. When it transfers", "cgJbCtRG1lY-00049-00025265-00025713": "to another narrative, its responses disappear from the journal.", "cgJbCtRG1lY-00050-00025713-00026191": "It has been largely cooperative since its containment. Its only requests so far have", "cgJbCtRG1lY-00051-00026191-00026663": "been for more narratives. It has expressed a preference for narratives with a large number", "cgJbCtRG1lY-00052-00026663-00027149": "of background characters, as this makes it easier for it to blend in and \"watch the good", "cgJbCtRG1lY-00053-00027149-00027793": "stuff.\" It has been recommended that, should it become uncooperative, it be confined to", "cgJbCtRG1lY-00054-00027793-00028204": "the journal until it becomes more amenable to staff requests.", "cgJbCtRG1lY-00055-00028204-00028838": "Researchers who desire more information on SCP-423 should read Experiment Log 423 A.", "cgJbCtRG1lY-00056-00028838-00029394": "Addendum 423-1: Researchers are reminded that all physical written material is a potential", "cgJbCtRG1lY-00057-00029394-00029971": "habitat for 423, and that all notes should therefore be taken electronically. If written", "cgJbCtRG1lY-00058-00029971-00030516": "notes must, for some reason, be taken, be sure to check for addenda from \"Guest Researcher", "cgJbCtRG1lY-00059-00030516-00030694": "Fred.\"", "cgJbCtRG1lY-00060-00030694-00031502": "Addendum 423-2: The use of SCP-583 to destroy SCP-423 has been suggested. While the SCP", "cgJbCtRG1lY-00061-00031502-00031964": "is not slated for destruction at the present time, it has been noted should circumstances", "cgJbCtRG1lY-00062-00031964-00032138": "change.", "cgJbCtRG1lY-00063-00032138-00032331": "Experiment Log 423 A", "cgJbCtRG1lY-00064-00032331-00032829": "Experiment Log for SCP-423 Approved by O5-█", "cgJbCtRG1lY-00065-00032829-00033607": "Monitored by O5-█, O5-██, O5-█ Project Head: Dr. E. Mann", "cgJbCtRG1lY-00066-00033607-00034078": "All researchers working with SCP-423 are encouraged to append their results to this experiment", "cgJbCtRG1lY-00067-00034078-00034307": "log in the following format:", "cgJbCtRG1lY-00068-00034307-00034546": "Date: ██/██/████ Test Material:", "cgJbCtRG1lY-00069-00034546-00034646": "Results:", "cgJbCtRG1lY-00070-00034646-00034746": "Notes:", "cgJbCtRG1lY-00071-00034746-00035221": "Date: ██/██/████ Test Material: Tom Sawyer, by Mark Twain", "cgJbCtRG1lY-00072-00035221-00035769": "Results: A character named Fred is mentioned at several points in the story, largely as", "cgJbCtRG1lY-00073-00035769-00036120": "an onlooker. No change to the story is noticed.", "cgJbCtRG1lY-00074-00036120-00036730": "Notes: \"This will serve as a baseline for future effects of SCP-423.\" - Dr. E. Mann", "cgJbCtRG1lY-00075-00036730-00037297": "Date: ██/██/████ Test Material: The Hobbit, by J. R. R. Tolkien", "cgJbCtRG1lY-00076-00037297-00038003": "Results: A 14th dwarf named Feredor is a member of the party. The narrative is largely the", "cgJbCtRG1lY-00077-00038003-00038514": "same, except that there are no references to a \"lucky number.\" Feredor is mentioned", "cgJbCtRG1lY-00078-00038514-00038997": "as surviving the Battle of Five Armies, but Oin is killed.", "cgJbCtRG1lY-00079-00038997-00039540": "Notes: \"SCP-423's role is larger in this work, allowing a better look at its effects. The", "cgJbCtRG1lY-00080-00039540-00040020": "dialog written for the character is similar to that written for the other dwarves. Other", "cgJbCtRG1lY-00081-00040020-00040530": "differences in text match Tolkien's writing style as used in the rest of the book.\" -Dr.", "cgJbCtRG1lY-00082-00040530-00040630": "E. Mann", "cgJbCtRG1lY-00083-00040630-00041093": "Date: ██/██/████ Test Material: Plain Journal", "cgJbCtRG1lY-00084-00041093-00041655": "Results: There was no result for some time, until one of the researchers wrote his name", "cgJbCtRG1lY-00085-00041655-00042286": "on the cover. The words \"Hi, there\" appeared underneath. A conversation was held, during", "cgJbCtRG1lY-00086-00042286-00042865": "which it was established that SCP-423 possessed both the ability and desire to communicate.", "cgJbCtRG1lY-00087-00042865-00043485": "Notes: \"This proves that SCP-423 is sentient. If it can be controlled, it could be useful", "cgJbCtRG1lY-00088-00043485-00044041": "in dealing with certain text-based SCPs. This bears further research.\" -Dr. E. Mann", "cgJbCtRG1lY-00089-00044041-00044650": "Date: ██/██/████ Test Material: Dragonquest, by Anne McCaffrey", "cgJbCtRG1lY-00090-00044650-00045412": "Results: A minor blue rider named F'Red appears in the story. No other changes are noted.", "cgJbCtRG1lY-00091-00045412-00045841": "Date: ██/██/████ Test Material: Harry Potter and the Half-Blood", "cgJbCtRG1lY-00092-00045841-00046124": "Prince, by J.K. Rowling", "cgJbCtRG1lY-00093-00046124-00046653": "Results: A wizard named Fred appeared. Very few changes in the story are noted, except", "cgJbCtRG1lY-00094-00046653-00047161": "one scene in which SCP-423 is confused with an existing character in the series.", "cgJbCtRG1lY-00095-00047161-00047754": "Notes: \"SCP-423 displayed paranormal abilities in the narrative, though nothing out of note", "cgJbCtRG1lY-00096-00047754-00048290": "for the fictional universe. However, when returned to the journal, SCP-423 said that", "cgJbCtRG1lY-00097-00048290-00048787": "it couldn't duplicate them outside of that particular narrative universe.\" - Dr. E. Mann", "cgJbCtRG1lY-00098-00048787-00049332": "Date: ██/██/████ Test Material: Ulysses, by James Joyce", "cgJbCtRG1lY-00099-00049332-00050029": "Results: SCP-423 immediately returned to the journal, where it wrote out \"Ow, ow, bad idea.\"", "cgJbCtRG1lY-00100-00050029-00050674": "Notes: \"Note this as a potential punishment for SCP-423 if it misbehaves.\" - Dr. E. Mann", "cgJbCtRG1lY-00101-00050674-00051299": "Date: ██/██/████ Test Material: The Draco Tavern, by Larry", "cgJbCtRG1lY-00102-00051299-00051399": "Niven", "cgJbCtRG1lY-00103-00051399-00052013": "Results: A new regular employee of the Draco Tavern showed up, named Fred. Only mentioned", "cgJbCtRG1lY-00104-00052013-00052550": "in passing save in the story \"Cruel and Unusual\", where he expressed sympathy for the Chirpsithra", "cgJbCtRG1lY-00105-00052550-00052650": "view.", "cgJbCtRG1lY-00106-00052650-00053127": "Notes: \"Either he's not completely human in outlook, or only acts that way when dealing", "cgJbCtRG1lY-00107-00053127-00053701": "with stories of aliens. We should probably test this further.\" - Dr D. Vettir", "cgJbCtRG1lY-00108-00053701-00054200": "Date: ██/██/████ Test Material: \"The Battle Hymn of the Republic\",", "cgJbCtRG1lY-00109-00054200-00054348": "by Julia Ward Howe.", "cgJbCtRG1lY-00110-00054348-00055004": "Results: verse 2, lines 1 and 3 altered. Rather than \"I have seen Him in the watch-fires of", "cgJbCtRG1lY-00111-00055004-00055458": "a hundred circling camps\" and \"I can read His righteous sentence by the dim and flaring", "cgJbCtRG1lY-00112-00055458-00056033": "lamps\", the lines now state \"Fred has seen Him in the watch-fires of a hundred circling", "cgJbCtRG1lY-00113-00056033-00056591": "camps\" and \"Fred can read His righteous sentence by the dim and flaring lamps\". Upon returning", "cgJbCtRG1lY-00114-00056591-00057099": "to the journal, SCP-423 wrote \"that was… interesting, but I don't think I want to try", "cgJbCtRG1lY-00115-00057099-00057199": "it again.\"", "cgJbCtRG1lY-00116-00057199-00057704": "Date: ██/██/████ Test Material: \"Mary Had A Little Lamb\" (verses", "cgJbCtRG1lY-00117-00057704-00058125": "1 and 2 only), by Sarah Josepha Hale.", "cgJbCtRG1lY-00118-00058125-00058717": "Results: References to \"Mary\" in verse 1 are now references to \"Freddy\"; references to", "cgJbCtRG1lY-00119-00058717-00059024": "\"her\" in verse 2 are now references to \"him\".", "cgJbCtRG1lY-00120-00059024-00059523": "Date: ██/██/████ Test Material: \"Mary Had A Little Lamb\" (full", "cgJbCtRG1lY-00121-00059523-00059816": "version), by Sarah Josepha Hale.", "cgJbCtRG1lY-00122-00059816-00060345": "Results: Verses 1 and 2 are now unaltered; a reference to \"the eager children\" in verse", "cgJbCtRG1lY-00123-00060345-00060729": "4 is now a reference to \"Fred and the children\".", "cgJbCtRG1lY-00124-00060729-00061127": "Date: ██/██/████ Test Material: House of Leaves (color version),", "cgJbCtRG1lY-00125-00061127-00061300": "by Mark Z. Danielewski.", "cgJbCtRG1lY-00126-00061300-00061991": "Results: A mailman named Fred delivers a letter to Will Navidson in page ███. Fred also", "cgJbCtRG1lY-00127-00061991-00062701": "appears as a bartender that attends Johnny, and one of the orderlies caring for Pelafina.", "cgJbCtRG1lY-00128-00062701-00063124": "SCP-423 expressed profound confusion after leaving this work. Of note is that all instances", "cgJbCtRG1lY-00129-00063124-00063516": "of \"Fred\" in the text were written in green.", "cgJbCtRG1lY-00130-00063516-00063952": "Date: ██/██/████ Test Material: Gadsby: Champion of Youth,", "cgJbCtRG1lY-00131-00063952-00064674": "by Ernest Vincent Wright. Gadsby is known for being an extended lipogram: a 50,110-word", "cgJbCtRG1lY-00132-00064674-00064911": "story written without any 'e's.", "cgJbCtRG1lY-00133-00064911-00065458": "Results: A minor character named Ford appeared in the novel.", "cgJbCtRG1lY-00134-00065458-00065850": "Date: ██/██/████ Test Material: A (non-pornographic) limerick", "cgJbCtRG1lY-00135-00065850-00066049": "about a man from Nantucket.", "cgJbCtRG1lY-00136-00066049-00066779": "Results: No change. SCP-423 subsequently explained that the given limerick was \"too small and", "cgJbCtRG1lY-00137-00066779-00067033": "too tight\", with insufficient \"flexibility\".", "cgJbCtRG1lY-00138-00067033-00067758": "Date: ██/██/████ Test Material: A book of 365 haiku.", "cgJbCtRG1lY-00139-00067758-00068239": "Results: Third line of thirteen separate haiku replaced with a five-syllable phrase mentioning", "cgJbCtRG1lY-00140-00068239-00068945": "Fred (\"Fred watched silently\", \"Fred is also here\", \"Only Fred remains\", etc).", "cgJbCtRG1lY-00141-00068945-00069393": "Date: ██/██/████ Test Material: The Frogs Who Desired A King,", "cgJbCtRG1lY-00142-00069393-00069995": "by Aesop, written using plastic letters with a magnetic backing applied to a metallic surface.", "cgJbCtRG1lY-00143-00069995-00070542": "Results: The penultimate sentence became, \"a big Stork that soon set to work gobbling", "cgJbCtRG1lY-00144-00070542-00071099": "them all up, except for one named Fred who hid.\" The \"new\" letters appeared to be of", "cgJbCtRG1lY-00145-00071099-00071512": "the same material and design of the original ones, and the weight of the complete setup", "cgJbCtRG1lY-00146-00071512-00071632": "remained the same.", "cgJbCtRG1lY-00147-00071632-00072280": "Date: ██/██/████ Test Material: Blood Meridian, by Cormac McCarthy.", "cgJbCtRG1lY-00148-00072280-00072799": "Results: In the introductory scene where Holden incites a mob to murder the Reverend by falsely", "cgJbCtRG1lY-00149-00072799-00073310": "accusing the Reverend of rape and bestiality, a bystander named Frederick is present in", "cgJbCtRG1lY-00150-00073310-00073858": "the mob; however, instead of participating, the bystander leaves in disgust. The narrator", "cgJbCtRG1lY-00151-00073858-00074198": "comments that \"The weak coward Frederick was never seen again.\"", "cgJbCtRG1lY-00152-00074198-00074681": "Date: ██/██/████ Test Material: ████████ Telephone", "cgJbCtRG1lY-00153-00074681-00074923": "Directory (2003).", "cgJbCtRG1lY-00154-00074923-00075122": "Results: No change.", "cgJbCtRG1lY-00155-00075122-00075825": "Date: ██/██/████ Test Material: 12 Angry Men, by Reginald Rose.", "cgJbCtRG1lY-00156-00075825-00076272": "Results: The list of characters specifies that the courthouse guard is named Fred; he", "cgJbCtRG1lY-00157-00076272-00076791": "is described as \"disappointed that he will be excluded from the jurors' deliberations\".", "cgJbCtRG1lY-00158-00076791-00077275": "Date: ██/██/████ Test Material: Mein Kampf, by Adolf Hitler", "cgJbCtRG1lY-00159-00077275-00077461": "(German original)", "cgJbCtRG1lY-00160-00077461-00077949": "Results: No change for the first minutes, followed by an insertion of multiple brief", "cgJbCtRG1lY-00161-00077949-00078433": "references to a distant, skeptical colleague named Friedrich into autobiographical fragments", "cgJbCtRG1lY-00162-00078433-00078983": "of chapters 2 to 8 of book. The inserts were in German, roughly consistent with the original", "cgJbCtRG1lY-00163-00078983-00079450": "style but containing a number of grammar and stylistic mistakes. Upon returning to the", "cgJbCtRG1lY-00164-00079450-00079918": "journal, SCP-423 remarked \"whew, that was hard!\"", "cgJbCtRG1lY-00165-00079918-00080517": "Notes: I am not sure what is more significant here: that 423 appears to possess a native", "cgJbCtRG1lY-00166-00080517-00081010": "tongue or that it was apparently able to obtain fairly good knowledge of German from the contents", "cgJbCtRG1lY-00167-00081010-00081532": "of a single book, even as long as this one. We should look deeper into its possible application", "cgJbCtRG1lY-00168-00081532-00081894": "to translating hitherto-undecipherable scripts — Dr Despair", "cgJbCtRG1lY-00169-00081894-00082485": "Date: ██/██/████ Test Material: Odyssey, by Homer (English", "cgJbCtRG1lY-00170-00082485-00082624": "Braille edition)", "cgJbCtRG1lY-00171-00082624-00083230": "Results: No change. SCP-423 left the book after 5 minutes, saying \"interesting but I", "cgJbCtRG1lY-00172-00083230-00083582": "think I'll leave this one for when I'm really bored\".", "cgJbCtRG1lY-00173-00083582-00083979": "Date: ██/██/████ Test Material: A hardcopy of this experiment", "cgJbCtRG1lY-00174-00083979-00084079": "log", "cgJbCtRG1lY-00175-00084079-00084531": "Results: Identical, except for the insertion of the words \"ruggedly handsome\" in several", "cgJbCtRG1lY-00176-00084531-00084757": "sections of the log.", "cgJbCtRG1lY-00177-00084757-00085204": "Date: ██/██/████ Test Material: The Kugelmass Episode, by Woody", "cgJbCtRG1lY-00178-00085204-00085651": "Allen, a story about a man who is able to travel into fiction.", "cgJbCtRG1lY-00179-00085651-00086002": "Results: Testing forbidden by O5-█.", "cgJbCtRG1lY-00180-00086002-00086651": "Date: ██/██/████ Test Material: SCP-826, using SCP-423 communication", "cgJbCtRG1lY-00181-00086651-00086862": "journal as a \"book\".", "cgJbCtRG1lY-00182-00086862-00087133": "Results: Testing forbidden by O5-█.", "cgJbCtRG1lY-00183-00087133-00087601": "Date: ██/██/████ Test Material: SCP-701", "cgJbCtRG1lY-00184-00087601-00087880": "Results: Testing forbidden by O5-█.", "cgJbCtRG1lY-00185-00087880-00088349": "Date: ██/██/████ Test Material: A Canadian five-dollar bill", "cgJbCtRG1lY-00186-00088349-00088914": "(2008 issue); the reverse of the bill contains a two-sentence passage from \"The Hockey Sweater\",", "cgJbCtRG1lY-00187-00088914-00089235": "by Roch Carrier, in French and in English.", "cgJbCtRG1lY-00188-00089235-00089829": "Results: First sentence remained intact. Second sentence, which describes how important skating", "cgJbCtRG1lY-00189-00089829-00090363": "rinks were in Carrier's childhood, now mentions life \"on the skating rink, with Fred\" (as", "cgJbCtRG1lY-00190-00090363-00090657": "well as \"sur la patinoire, avec Fred\").", "cgJbCtRG1lY-00191-00090657-00091130": "Notes: The bill was first tested in a change machine and accepted as legitimate. After", "cgJbCtRG1lY-00192-00091130-00091718": "SCP-423 left the bill, it was tested in the same change machine and rejected as counterfeit.", "cgJbCtRG1lY-00193-00091718-00092325": "Date: ██/██/████ Test Material: Green Eggs and Ham by Dr. Seuss", "cgJbCtRG1lY-00194-00092325-00092795": "Results: Halfway through the book, Sam-I-Am asks the protagonist \"Would you eat them here", "cgJbCtRG1lY-00195-00092795-00093352": "with Fred? Would you eat them with some bread?\". The protagonist refuses. No edited nor additional", "cgJbCtRG1lY-00196-00093352-00093568": "illustrations were included.", "cgJbCtRG1lY-00197-00093568-00094170": "Notes: After returning to his journal, SCP-423 noted \"That was fun.\"", "cgJbCtRG1lY-00198-00094170-00094529": "Date: ██/██/████ Test Material: The Fellowship of the Ring,", "cgJbCtRG1lY-00199-00094529-00094730": "by J. R. R. Tolkien.", "cgJbCtRG1lY-00200-00094730-00095360": "Results: A hobbit named Fredegar Burrowes, noted as a friend of Samwise Gamgee, accompanies", "cgJbCtRG1lY-00201-00095360-00095638": "Frodo Baggins and his party throughout the book.", "cgJbCtRG1lY-00202-00095638-00096193": "Notes: Of particular note is that Oin, noted as having been killed in 423's version of", "cgJbCtRG1lY-00203-00096193-00096617": "the Hobbit, is mentioned as surviving in this book.", "cgJbCtRG1lY-00204-00096617-00097068": "Date: ██/██/████ Test Material: SCP-140", "cgJbCtRG1lY-00205-00097068-00097638": "Results: Testing forbidden by O5-█. Note: Without permission, Researcher D██████,", "cgJbCtRG1lY-00206-00097638-00098208": "who was working with SCP-140 at the time, put the two books together, despite training", "cgJbCtRG1lY-00207-00098208-00098855": "in resisting memetic effects. Words appeared rapidly on SCP-140's pages, at a rate of roughly", "cgJbCtRG1lY-00208-00098855-00099505": "1 page filled every 12 seconds until SCP-423 returned to its journal, and the words disappeared", "cgJbCtRG1lY-00209-00099505-00100206": "from the pages of SCP-140. SCP-423 later stated that it was \"Extremely painful\", and felt", "cgJbCtRG1lY-00210-00100206-00100517": "like it was being \"ripped apart.\"", "cgJbCtRG1lY-00211-00100517-00100994": "Date: ██/██/████ Test Material: SCP-1425", "cgJbCtRG1lY-00212-00100994-00101317": "Results: Testing forbidden by O5-█.", "cgJbCtRG1lY-00213-00101317-00101813": "Date: ██/██/████ Test Material: SCP-1230", "cgJbCtRG1lY-00214-00101813-00102151": "Results: Pending O5 approval.", "cgJbCtRG1lY-00215-00102151-00102541": "Date: ██/██/████ Test Material: SCP-1195", "cgJbCtRG1lY-00216-00102541-00103091": "Results: Pending O5 approval. Testing forbidden by O5-██.", "cgJbCtRG1lY-00217-00103091-00103564": "Date: ██/██/████ Test Material: A list of class-D personnel", "cgJbCtRG1lY-00218-00103564-00103929": "to be terminated at the first of the month, names included.", "cgJbCtRG1lY-00219-00103929-00104380": "Results: The line ''Class-D personnel to be de-commissioned as of ██/██/████'' changed", "cgJbCtRG1lY-00220-00104380-00104843": "to ''Class-D personnel to be released as of ██/██/████'', all names remain", "cgJbCtRG1lY-00221-00104843-00105372": "as first written down. SCP-423 writes in the journal ''Now that's just heartless.''", "cgJbCtRG1lY-00222-00105372-00106000": "Notes: It is conclusive that SCP-423 has the ability to not only feel emotion but has a", "cgJbCtRG1lY-00223-00106000-00106228": "belief in the importance of life.", "cgJbCtRG1lY-00224-00106228-00106644": "Date: ██/██/████ Test Material: A twenty-minute ballet for", "cgJbCtRG1lY-00225-00106644-00107148": "eight dancers (four male and four female), described in Rudolf Laban's \"Labanotation\"", "cgJbCtRG1lY-00226-00107148-00107444": "system for recording human movement.", "cgJbCtRG1lY-00227-00107444-00108075": "Results: Notation indicates that halfway through the ballet, a fifth male dancer walks onstage,", "cgJbCtRG1lY-00228-00108075-00108416": "looks at the other dancers, shrugs his shoulders, and walks off.", "cgJbCtRG1lY-00229-00108416-00108888": "Date: ██/██/████ Test Material: A logic puzzle (as published", "cgJbCtRG1lY-00230-00108888-00109436": "in [REDACTED] logic puzzle magazine), describing how five different people took their driving", "cgJbCtRG1lY-00231-00109436-00109975": "tests, in five different vehicles, on five different days, and made five different errors;", "cgJbCtRG1lY-00232-00109975-00110482": "as is standard for logic puzzles of this sort, solvers are to determine which student drove", "cgJbCtRG1lY-00233-00110482-00110808": "which vehicle and made which error on which day.", "cgJbCtRG1lY-00234-00110808-00111349": "Results: A driving examiner named Fred is mentioned as having been present during all", "cgJbCtRG1lY-00235-00111349-00111897": "tests. Upon subsequent questioning, SCP-423 was able to correctly state which driver made", "cgJbCtRG1lY-00236-00111897-00112540": "which error in which vehicle on which day. When asked how it knew this, SCP-423 did not", "cgJbCtRG1lY-00237-00112540-00112965": "explain the series of logical inferences, deductions, and conclusions by which such", "cgJbCtRG1lY-00238-00112965-00113433": "puzzles are typically solved, but rather simply stated that it \"was right there the whole", "cgJbCtRG1lY-00239-00113433-00113533": "time\".", "cgJbCtRG1lY-00240-00113533-00113976": "Date: ██/██/████ Test Material: The Gardens of the Moon, by", "cgJbCtRG1lY-00241-00113976-00114090": "Steven Erikson", "cgJbCtRG1lY-00242-00114090-00114819": "Results: The Dramatis Personae in the start of the book now mentions Reader, a soldier", "cgJbCtRG1lY-00243-00114819-00115444": "in the Bridgeburners, and Fred, a Daru patron of the Phoenix Inn. In the second chapter,", "cgJbCtRG1lY-00244-00115444-00115927": "following the fall of Pale, the Bridgeburners that arrive for Hairlock include a fifth person,", "cgJbCtRG1lY-00245-00115927-00116625": "who is unnamed and doesn't speak, but can later be identified as Reader. In many subsequent", "cgJbCtRG1lY-00246-00116625-00117132": "encounters with the Bridgeburners, the soldier Reader is also present. This character doesn't", "cgJbCtRG1lY-00247-00117132-00117572": "have any lines, and is normally found with a book in his hand.", "cgJbCtRG1lY-00248-00117572-00118114": "In chapter 5, during Kruppe's dream, Kruppe sees a figure within the Gadrobi Shantytown", "cgJbCtRG1lY-00249-00118114-00118627": "who, he says, greatly reminds him of his friend Fred, who he saw just the other day in the", "cgJbCtRG1lY-00250-00118627-00119209": "Phoenix Inn. From chapter 6 on, Fred is to be found in the Phoenix Inn.", "cgJbCtRG1lY-00251-00119209-00119783": "Interestingly, for the garden party on Lady Simtal's estate, both Fred and Reader are", "cgJbCtRG1lY-00252-00119783-00120458": "guests. Bridgeburner and Daru viewpoint characters alike comment on how they look vaguely similar.", "cgJbCtRG1lY-00253-00120458-00120977": "Apart from the minor changes, the book has exactly the same ending as before, though.", "cgJbCtRG1lY-00254-00120977-00121623": "Upon returning to the journal, SCP-423 wrote only \"…\" when questioned. After a few minutes,", "cgJbCtRG1lY-00255-00121623-00122216": "it finally wrote \"Sorry, that was interesting, but exhausting.\" SCP-423 expressed an interest", "cgJbCtRG1lY-00256-00122216-00122600": "in the remaining books of the series. This has been noted and will be considered as a", "cgJbCtRG1lY-00257-00122600-00122769": "reward for good behaviour.", "cgJbCtRG1lY-00258-00122769-00123418": "Notes: \"This has proven that 423 can be in multiple places within the same narrative,", "cgJbCtRG1lY-00259-00123418-00123891": "although it seems to tire it out. - Dr. R. Karma\"", "cgJbCtRG1lY-00260-00123891-00124316": "Date: ██/██/████ Test Material: Candidate Multilinear Maps,", "cgJbCtRG1lY-00261-00124316-00124766": "by Sanjam Garg, published in 2013 as his doctoral thesis", "cgJbCtRG1lY-00262-00124766-00125354": "Results: Approximately 10 seconds after entering, SCP-423 returned to the journal and wrote", "cgJbCtRG1lY-00263-00125354-00125590": "\"Sorry, not enough room for me.\"", "cgJbCtRG1lY-00264-00125590-00126167": "Notes: \"It seems that 423 needs to have a narrative to work off. This has been noted", "cgJbCtRG1lY-00265-00126167-00126481": "for the future. - Dr. R. Karma\"", "cgJbCtRG1lY-00266-00126481-00126804": "Date: ██/██/████ Test Material: A print-out of source code", "cgJbCtRG1lY-00267-00126804-00127193": "for a simple \"Hello World\" program in C#", "cgJbCtRG1lY-00268-00127193-00127609": "Results: The source code now has a number of additional comments alongside the source", "cgJbCtRG1lY-00269-00127609-00128128": "code professing confusion about certain aspects of programming. On returning to the journal,", "cgJbCtRG1lY-00270-00128128-00128569": "SCP-423 wrote out \"Well, that was a first.\"", "cgJbCtRG1lY-00271-00128569-00129053": "Date: ██/██/████ Test Material: Head-First C# 3rd Edition (first", "cgJbCtRG1lY-00272-00129053-00129328": "printing), by Andrew Stellman and Jennifer Greene", "cgJbCtRG1lY-00273-00129328-00129951": "Results: A number of examples involving named male characters have had these characters", "cgJbCtRG1lY-00274-00129951-00130577": "renamed to Fred. The puzzles are also all filled in. Around page 100 or so, notes start", "cgJbCtRG1lY-00275-00130577-00131294": "appearing here and there. No substantial changes are noted until page 698, where a typo identified", "cgJbCtRG1lY-00276-00131294-00131832": "in the errata for the book was corrected. In subsequent pages, a number of typos and", "cgJbCtRG1lY-00277-00131832-00132322": "language problems were corrected in code snippets and descriptions, matching the errors reported", "cgJbCtRG1lY-00278-00132322-00132974": "in the errata, with the exception of screenshots. On returning to the journal, SCP-423 reported", "cgJbCtRG1lY-00279-00132974-00133517": "that it found that \"fun, but unusual.\" On being questioned on its understanding of the", "cgJbCtRG1lY-00280-00133517-00134070": "language, SCP-423 stated that it could write and understand C#, and expressed a desire", "cgJbCtRG1lY-00281-00134070-00134244": "to use Visual Studio.", "cgJbCtRG1lY-00282-00134244-00134887": "Notes: \"423 seems to be both capable and interested in learning, provided there is some narrative", "cgJbCtRG1lY-00283-00134887-00135328": "reason for it to learn. A potential future experiment could involve us attempting to", "cgJbCtRG1lY-00284-00135328-00135935": "decant it into a computer without an internet connection. - Dr. R. Karma\"", "cgJbCtRG1lY-00285-00135935-00136318": "Date: ██/██/████ Test Material: Secret of the Ninja (Choose", "cgJbCtRG1lY-00286-00136318-00136568": "Your Own Adventure #16), by Jay Leibold", "cgJbCtRG1lY-00287-00136568-00137161": "Results: The viewpoint character is initially accompanied by a character named Fred, who", "cgJbCtRG1lY-00288-00137161-00137673": "is another student at the Dojo. Several of the choice descriptions which lead to a negative", "cgJbCtRG1lY-00289-00137673-00138077": "ending for the protagonist and his companions are changed to contain a phrase indicating", "cgJbCtRG1lY-00290-00138077-00138297": "Fred does not accompany the protagonist.", "cgJbCtRG1lY-00291-00138297-00138824": "Notes: \"423 does not seem significantly hindered by the book's branching narrative, nor by", "cgJbCtRG1lY-00292-00138824-00139060": "the presence of multiple endings.\" - Researcher ████", "cgJbCtRG1lY-00293-00139060-00139787": "Date: ██/██/2015 Test Material: Printed copy of an ASCII art", "cgJbCtRG1lY-00294-00139787-00140074": "rendition of the Mona Lisa, by Leonardo da Vinci", "cgJbCtRG1lY-00295-00140074-00140712": "Results: All punctuation used to simulate the shading of the original work is replaced", "cgJbCtRG1lY-00296-00140712-00141290": "with the letters \"F\", \"r\", \"e\", and \"d\" (in upper and lower case).", "cgJbCtRG1lY-00297-00141290-00141846": "Notes: When questioned about the extent of its ability to completely modify textual representations", "cgJbCtRG1lY-00298-00141846-00142575": "of imagery (as opposed to merely substituting characters), SCP-423 acknowledged the possibility,", "cgJbCtRG1lY-00299-00142575-00143100": "responding with \"I guess so, maybe, but I'm not really good at art.\" Further inquiry is", "cgJbCtRG1lY-00300-00143100-00143227": "suggested.", "cgJbCtRG1lY-00301-00143227-00143645": "Date: ██/██/████ Test Material: SCP-085", "cgJbCtRG1lY-00302-00143645-00144003": "Results: Pending O5 approval.", "cgJbCtRG1lY-00303-00144003-00144358": "Date: ██/██/████ Test Material: the Frequently Asked Questions", "cgJbCtRG1lY-00304-00144358-00144895": "document for the Usenet newsgroup \"alt.adjective.noun.verb.verb.verb\"", "cgJbCtRG1lY-00305-00144895-00145607": "Results: A sentence is added to the section of the document which describes the newsgroup's", "cgJbCtRG1lY-00306-00145607-00146237": "genesis, stating \"alt.anomalous.Fred.perplexed.baffled.moderately-amused\".", "cgJbCtRG1lY-00307-00146237-00146800": "Date: ██/██/████ Test Material: 施氏食狮史 (\"Lion-Eating", "cgJbCtRG1lY-00308-00146800-00147455": "Poet In The Stone Den\"), by Yuen Ren Chao. \"Lion-Eating Poet\" is a 92-character poem", "cgJbCtRG1lY-00309-00147455-00148037": "written in Classical Chinese, in which every syllable is pronounced \"shi\" (albeit with", "cgJbCtRG1lY-00310-00148037-00148201": "varying tones).", "cgJbCtRG1lY-00311-00148201-00148832": "Results: SCP-423 demanifested from its journal, but did not manifest within the test document.", "cgJbCtRG1lY-00312-00148832-00149381": "After 10 minutes, researchers were about to report a containment breach, when SCP-423", "cgJbCtRG1lY-00313-00149381-00149815": "remanifested within its journal, stating that it had \"got[ten] lost trying to find the way", "cgJbCtRG1lY-00314-00149815-00149915": "in\".", "cgJbCtRG1lY-00315-00149915-00150375": "Date:██/██/████ Test Material: World War Z, by Max Brooks.", "cgJbCtRG1lY-00316-00150375-00150828": "The book consists of multiple small interview-like stories told from the perspective of survivors", "cgJbCtRG1lY-00317-00150828-00151028": "of a zombie apocalypse.", "cgJbCtRG1lY-00318-00151028-00151696": "Results: SCP-423 demanifested from the journal, and was discovered to have added in the accounts", "cgJbCtRG1lY-00319-00151696-00152252": "of a character named Fred, who survived in a bookstore on [DATA EXPUNGED] Road in New", "cgJbCtRG1lY-00320-00152252-00152669": "York. A team has been dispatched to investigate the named location.", "cgJbCtRG1lY-00321-00152669-00153200": "Date: ██/██/████ Test Material: Marvel Masterworks: The X-Men", "cgJbCtRG1lY-00322-00153200-00153833": "Vol 1, By Stan Lee (writer) and Jack Kirby (artist). The book is a trade paperback collection", "cgJbCtRG1lY-00323-00153833-00154275": "of the first 10 issues of the comic book series \"The X-Men\".", "cgJbCtRG1lY-00324-00154275-00154790": "Results: The collection now contains numerous references to Fred Wordsworth, one of the", "cgJbCtRG1lY-00325-00154790-00155330": "students of Xavier's School for Gifted Youngsters. This character is described as a mutant possessing", "cgJbCtRG1lY-00326-00155330-00155797": "the ability to physically enter and alter any text, but that this power has \"made him", "cgJbCtRG1lY-00327-00155797-00156433": "invisible and intangible\". By issue #5, the character has become a second-string member", "cgJbCtRG1lY-00328-00156433-00156993": "of the X-Men unit under the alias \"Bookworm\". The character indirectly participates in several", "cgJbCtRG1lY-00329-00156993-00157511": "plot points through utilization of his abilities, in one instance distracting a villain by altering", "cgJbCtRG1lY-00330-00157511-00157628": "nearby signs.", "cgJbCtRG1lY-00331-00157628-00158288": "Notes: SCP-423 was found to have altered certain instances of text within in the artwork, but", "cgJbCtRG1lY-00332-00158288-00158901": "was completely unable to affect other instances upon request. Investigation has revealed that", "cgJbCtRG1lY-00333-00158901-00159358": "all susceptible text was added by the comic's letterer (exclusively responsible for the", "cgJbCtRG1lY-00334-00159358-00159924": "addition of all text found in a comic) rather than the inker (exclusively responsible for", "cgJbCtRG1lY-00335-00159924-00160373": "finalizing artwork). Further study is recommended.", "cgJbCtRG1lY-00336-00160373-00160791": "Date: ██/██/████ Test Material: the poem Incident by Countee", "cgJbCtRG1lY-00337-00160791-00161257": "Cullen, depicting Cullen's experiences with anti-black racism, as a child visiting Baltimore.", "cgJbCtRG1lY-00338-00161257-00162024": "Results: The ninth line of the poem is changed from \"I saw the whole of Baltimore\" to \"Fred", "cgJbCtRG1lY-00339-00162024-00162298": "showed me all of Baltimore\".", "cgJbCtRG1lY-00340-00162298-00162813": "Notes: SCP-423 seems reluctant to portray itself as either the perpetrator or the victim", "cgJbCtRG1lY-00341-00162813-00162995": "of racism.", "cgJbCtRG1lY-00342-00162995-00163407": "Date: ██/██/████ Test Material: Slaughterhouse-Five, by Kurt", "cgJbCtRG1lY-00343-00163407-00163998": "Vonnegut. The novel is a semi-autobiographical account of Vonnegut's experience as an American", "cgJbCtRG1lY-00344-00163998-00164673": "prisoner of war during the 1945 bombing of Dresden, Germany during World War II.", "cgJbCtRG1lY-00345-00164673-00165213": "Results: All mention of Kurt Vonnegut within the novel, excluding within the foreword,", "cgJbCtRG1lY-00346-00165213-00165844": "is altered to describe SCP-423 (i.e. \"That was I. That was me. That was the author of", "cgJbCtRG1lY-00347-00165844-00166401": "this book.\" Was changed to read \"That was Fred. That was not me. That was not the author", "cgJbCtRG1lY-00348-00166401-00166548": "of this book.\").", "cgJbCtRG1lY-00349-00166548-00167037": "Notes: As Kurt Vonnegut himself was not mentioned for most of the novel, he could technically", "cgJbCtRG1lY-00350-00167037-00167282": "be described as a \"minor\" character.", "cgJbCtRG1lY-00351-00167282-00167721": "Date: ██/██/████ Test Material: The Outsiders by S. E. Hinton.", "cgJbCtRG1lY-00352-00167721-00168254": "Results: A new member of the \"Socs\" accompanies Robert during the scene in which Robert is", "cgJbCtRG1lY-00353-00168254-00168800": "murdered. When Ponyboy wakes up after having attempted to be drowned, Johnny mentions that", "cgJbCtRG1lY-00354-00168800-00169348": "someone \"unimpressivly handsome\" had introduced himself as Fred, before punching Johnny in", "cgJbCtRG1lY-00355-00169348-00169898": "the face, then \"running outta there like lightning.\" After returning to the journal, SCP-423 remarked,", "cgJbCtRG1lY-00356-00169898-00170395": "\"I know that you guys record this, and I didn't want to ruin the ending for anyone who hadn't", "cgJbCtRG1lY-00357-00170395-00170935": "read the book.\" It is to be noted that at the end of the book, [REDACTED].", "cgJbCtRG1lY-00358-00170935-00171362": "Date: ██/██/████ Test Material: Fred's Story by Researcher", "cgJbCtRG1lY-00359-00171362-00171922": "Torrez, a small novella written specifically to test SCP-423's abilities. The novella is", "cgJbCtRG1lY-00360-00171922-00172430": "set in a fantasy kingdom whose inhabitants are all beautiful women - when the kingdom", "cgJbCtRG1lY-00361-00172430-00172902": "is attacked by a demonic force, the kingdom's queen creates a ritual to summon a hero from", "cgJbCtRG1lY-00362-00172902-00173480": "another dimension to save them. The hero is never given a name, but it is mentioned that", "cgJbCtRG1lY-00363-00173480-00173880": "he is male and can transfer his consciousness to different works of fiction.", "cgJbCtRG1lY-00364-00173880-00174430": "Results: The hero is left nameless and the novella is left unchanged, aside from an added", "cgJbCtRG1lY-00365-00174430-00174999": "sentence in chapter 2 which mentions that one of the queen's assistants is named Frederica.", "cgJbCtRG1lY-00366-00174999-00175579": "After SCP-423 demanifested from the novella, it noted, \"I appreciate the offer, but I just", "cgJbCtRG1lY-00367-00175579-00175816": "can't. I never deserved to be in the spotlight.\"", "cgJbCtRG1lY-00368-00175816-00176262": "Date: ██/██/████ Test Material: The Last Question, by Isaac", "cgJbCtRG1lY-00369-00176262-00176910": "Asimov. This test was conducted not using physically printed material, but a 9.7-inch", "cgJbCtRG1lY-00370-00176910-00177510": "A█████ K█████ e-reader tablet utilizing electronic paper technology.", "cgJbCtRG1lY-00371-00177510-00177958": "Electronic paper is able to retain a static image indefinitely without electricity, requiring", "cgJbCtRG1lY-00372-00177958-00178471": "power only for the initial rendering. Image remains as a suspension of pigments in an", "cgJbCtRG1lY-00373-00178471-00178948": "oil-like base once rendered. Entire story was rendered on a single screen in a small", "cgJbCtRG1lY-00374-00178948-00179467": "font. Wireless functionality was disabled before testing by physically severing circuit", "cgJbCtRG1lY-00375-00179467-00179874": "traces on the device's printed circuit board as a precaution.", "cgJbCtRG1lY-00376-00179874-00180415": "Results: A character named FR-33D is inserted into the third section of the story almost", "cgJbCtRG1lY-00377-00180415-00180940": "instantaneously, with a single line in response to another character's comment on the rate", "cgJbCtRG1lY-00378-00180940-00181629": "at which humans are populating the galaxy. SCP-423 stated afterwards, \"Good story, but", "cgJbCtRG1lY-00379-00181629-00182120": "what was that? It felt… strange. It was very easy to move through - not at all unpleasant.", "cgJbCtRG1lY-00380-00182120-00182633": "It felt like there was something 'below' the story, if that makes sense. Can we do more", "cgJbCtRG1lY-00381-00182633-00182757": "like that?\"", "cgJbCtRG1lY-00382-00182757-00183445": "Notes: \"It is unclear whether SCP-423 'moved' through the internal circuitry of the device", "cgJbCtRG1lY-00383-00183445-00184089": "or simply the physical pigment-in-oil suspension of the electronic paper material. Changes", "cgJbCtRG1lY-00384-00184089-00184704": "occurred much faster than in tests with ink-on-paper. Recommend further testing with other substrates", "cgJbCtRG1lY-00385-00184704-00185197": "and form factors. Electronic paper appears to be close enough to printed material as", "cgJbCtRG1lY-00386-00185197-00185921": "to be compatible with SCP-423. What else might be compatible? Text painted on a wall? Stitched", "cgJbCtRG1lY-00387-00185921-00186295": "into fabric? Written on a cake with icing?\" - Dr. ██████", "cgJbCtRG1lY-00388-00186295-00186798": "Date: ██/██/████ Test Material: If on a winter's night a traveler,", "cgJbCtRG1lY-00389-00186798-00187462": "by Italo Calvino (English translation by William Weaver), a metafictional novel about interrupted", "cgJbCtRG1lY-00390-00187462-00187989": "and unfinished narratives, half of whose content is a second-person narrative describing a", "cgJbCtRG1lY-00391-00187989-00188441": "reader's increasingly frantic attempts to obtain and read a copy of If on a winter's", "cgJbCtRG1lY-00392-00188441-00188960": "night a traveler only to find that every copy is flawed such that every other chapter is", "cgJbCtRG1lY-00393-00188960-00189405": "from a different imaginary novel, and the other half is the aforementioned chapters", "cgJbCtRG1lY-00394-00189405-00189619": "from imaginary novels.", "cgJbCtRG1lY-00395-00189619-00190101": "Results: In the section where the protagonist angrily returns the flawed copy of the novel", "cgJbCtRG1lY-00396-00190101-00190600": "to the bookseller in hopes of either obtaining a proper copy or finding out the conclusion", "cgJbCtRG1lY-00397-00190600-00191114": "to the chapter of the imaginary novel, another angry customer named Fred tells the bookseller", "cgJbCtRG1lY-00398-00191114-00191384": "that \"if this is a joke, it's not funny.\"", "cgJbCtRG1lY-00399-00191384-00191880": "Date: ██/██/████ Test Material: A version of In Search of Lost", "cgJbCtRG1lY-00400-00191880-00192467": "Time by Marcel Proust (English translation by D.J. Enright), considered one of the longest", "cgJbCtRG1lY-00401-00192467-00192902": "works of fiction in history, in which all seven volumes have been custom-bound into", "cgJbCtRG1lY-00402-00192902-00193345": "one book with all indications of differing volumes removed.", "cgJbCtRG1lY-00403-00193345-00193910": "Results: After several minutes, Fred only appears within the first three volumes, Swann's", "cgJbCtRG1lY-00404-00193910-00194440": "Way, In the Shadow of Young Girls in Flower, and The Guermantes Way, before all references", "cgJbCtRG1lY-00405-00194440-00195182": "of him cease. Upon return to the journal, SCP-423 expressed feelings of surprise, stating,", "cgJbCtRG1lY-00406-00195182-00195754": "\"Great story, but I took a peek and how long it went and wow is it long. I'm going to need", "cgJbCtRG1lY-00407-00195754-00195981": "to come back to this one.\"", "cgJbCtRG1lY-00408-00195981-00196539": "Notes: Along with the aforementioned Erikson test, this could be an indicator that SCP-423", "cgJbCtRG1lY-00409-00196539-00196901": "has an upper limit as to the length of the works he can manifest in.", "cgJbCtRG1lY-00410-00196901-00197600": "Date: ██/██/████ Test Materials: SCP-3450, printed onto standard", "cgJbCtRG1lY-00411-00197600-00197764": "computer paper.", "cgJbCtRG1lY-00412-00197764-00198024": "Results: Testing forbidden by 05-█.", "cgJbCtRG1lY-00413-00198024-00198769": "Notes: SCP-423 had learned of this test after denial due to Junior Researcher █████████ accidentally", "cgJbCtRG1lY-00414-00198769-00199370": "leaving a notepad expressing disappointment at the test's denial near 423's journal. SCP-423", "cgJbCtRG1lY-00415-00199370-00199857": "wrote that \"The irony of interacting with a Self-Insert fanfic isn't lost on me\".", "cgJbCtRG1lY-00416-00199857-00200420": "Date: ██/██/████ Test Material: Of Mice and Men by John Steinbeck.", "cgJbCtRG1lY-00417-00200420-00200905": "Results: A character named Freddy appears multiple times throughout the book, working", "cgJbCtRG1lY-00418-00200905-00201511": "as a farmhand on the ranch. The narrator describes him as \"a man whose handsomeness is all the", "cgJbCtRG1lY-00419-00201511-00201949": "more apparent when compared to the other hands at the ranch, as he is not nearly as worn", "cgJbCtRG1lY-00420-00201949-00202527": "down\". His largest appearance is during the section when George Milton and Lennie Small", "cgJbCtRG1lY-00421-00202527-00203133": "first arrive on the ranch. As he passes the two protagonists by, he comments on the size", "cgJbCtRG1lY-00422-00203133-00203704": "of Lennie, remarking that he \"looks like a bull who learned how to walk on his hind legs\".", "cgJbCtRG1lY-00423-00203704-00204093": "Date: ██/██/████ Test Material: 300 children's building block", "cgJbCtRG1lY-00424-00204093-00204193": "toys.", "cgJbCtRG1lY-00425-00204193-00204375": "Result: No Change.", "cgJbCtRG1lY-00426-00204375-00205004": "Notes: The result of this test is rather inconclusive. Did SCP-423 consider the letters on the blocks", "cgJbCtRG1lY-00427-00205004-00205598": "a picture instead of text? Could it only affect one block and \"not have enough room\"? Or can", "cgJbCtRG1lY-00428-00205598-00206128": "it simply not affect this form of writing? More tests like this will have to be conducted.", "cgJbCtRG1lY-00429-00206128-00206880": "Date: ██/██/████ Test Material: SCP-2236. SCP-2236 was used", "cgJbCtRG1lY-00430-00206880-00207294": "to examine texts known to have been affected by SCP-423.", "cgJbCtRG1lY-00431-00207294-00208066": "Result: First few texts examined exhibited no change. In subsequently-examined texts,", "cgJbCtRG1lY-00432-00208066-00208726": "references to SCP-423 in the text were, when examined using SCP-2236, interpreted as descriptions", "cgJbCtRG1lY-00433-00208726-00209411": "of \"Fred\" seeking to hide or avoid observation. When returned to the journal, a comment in", "cgJbCtRG1lY-00434-00209411-00210129": "appeared in the journal reading \"That was rude.\" This comment, when examined using SCP-2236,", "cgJbCtRG1lY-00435-00210129-00210446": "appeared as a string of expletives.", "cgJbCtRG1lY-00436-00210446-00210859": "Date: ██/██/████ Test Material: A journal with \"Mary Had a", "cgJbCtRG1lY-00437-00210859-00211069": "Little Lamb\", but written in invisible ink", "cgJbCtRG1lY-00438-00211069-00211780": "Result: Same as the last time \"Mary Had a Little Lamb\" was used. SCP-423 manifested", "cgJbCtRG1lY-00439-00211780-00212419": "itself in invisible ink. When asking SCP-423 if he noticed the change in ink, he did admit", "cgJbCtRG1lY-00440-00212419-00213023": "that the document seemed slightly different. Notes: It seems that SCP-423 might be able", "cgJbCtRG1lY-00441-00213023-00213438": "to notice specific patterns and differences between text, explaining his adherence to", "cgJbCtRG1lY-00442-00213438-00213852": "story-specific restrictions. This is confirmed by this experiment.", "cgJbCtRG1lY-00443-00213852-00214385": "Date: ██/██/████ Test Material: A copy of the Voynich Manuscript", "cgJbCtRG1lY-00444-00214385-00215036": "Result: After five minutes in which the text did not change, SCP-423 explained that the", "cgJbCtRG1lY-00445-00215036-00215671": "topic was technical up to a level where SCP-423 could not understand, though SCP-423 explained", "cgJbCtRG1lY-00446-00215671-00216086": "it did seem that the pictures in the Voynich Manuscript matched the captions below.", "cgJbCtRG1lY-00447-00216086-00216560": "Date: ██/██/████ Test Material: A hard copy of the Wikipedia", "cgJbCtRG1lY-00448-00216560-00216759": "page on the Poincaré conjecture", "cgJbCtRG1lY-00449-00216759-00217644": "Result: The only place where SCP-423 manifested was in one of the bibliographies. SCP-423", "cgJbCtRG1lY-00450-00217644-00218007": "stated that it could not find a good place to appear due to lack of knowledge of the", "cgJbCtRG1lY-00451-00218007-00218557": "Poincaré conjecture, though it was impressed by Poincaré's math skills.", "cgJbCtRG1lY-00452-00218557-00219050": "Date: ██/██/████ Test Material: Metaphors, by Sylvia Plath,", "cgJbCtRG1lY-00453-00219050-00219573": "a nine-line poem in which each line is a nine-syllable metaphor for the same subject.", "cgJbCtRG1lY-00454-00219573-00220216": "Result: No change. When SCP-423 returned to its journal, it stated that \"whatever she's", "cgJbCtRG1lY-00455-00220216-00220707": "doing in there, it's too crowded, there's no room for me. I really don't think I should", "cgJbCtRG1lY-00456-00220707-00221194": "be in there, it's kind of private?\", and refused to comment further.", "cgJbCtRG1lY-00457-00221194-00221648": "Date: ██/██/████ Test Material: A copy of the film script for", "cgJbCtRG1lY-00458-00221648-00221816": "\"Inception\", by Christopher Nolan", "cgJbCtRG1lY-00459-00221816-00222429": "Result: SCP-423 appeared as a minor character appearing in some of the dreams, as well as", "cgJbCtRG1lY-00460-00222429-00222923": "the limbo state for the movie. It adhered to the capitalization format of the script", "cgJbCtRG1lY-00461-00222923-00223424": "(\"FRED\") as well as his name put in the middle of the page when appearing, with a line after", "cgJbCtRG1lY-00462-00223424-00223964": "his name each time. SCP-423 states that it highly enjoyed the script, though he was a", "cgJbCtRG1lY-00463-00223964-00224453": "bit confused by \"FADE OUT\" as well as \"CREDITS\", since this was the first time it was exposed", "cgJbCtRG1lY-00464-00224453-00224631": "to a movie script.", "cgJbCtRG1lY-00465-00224631-00225086": "Date: ██/██/████ Test Material: A copy of the script for \"Heaven", "cgJbCtRG1lY-00466-00225086-00225186": "Sent\", from Doctor Who", "cgJbCtRG1lY-00467-00225186-00226131": "Result: References to sculptures on the wall resembling SCP-423's usual look. SCP-423 explained", "cgJbCtRG1lY-00468-00226131-00226569": "that the tight story made it too difficult for him to manifest himself as an actual character,", "cgJbCtRG1lY-00469-00226569-00227074": "though he vastly enjoyed The Doctor's fantastic performance, which he claimed he experienced", "cgJbCtRG1lY-00470-00227074-00227636": "not as 4 billion years but only an hour (as long as the TV episode).", "cgJbCtRG1lY-00471-00227636-00228182": "Notes: It seems that if a story is very \"contained\" (any other characters would have a severe", "cgJbCtRG1lY-00472-00228182-00228735": "change in plot, or make no sense) with only a bare minimal amount of main characters,", "cgJbCtRG1lY-00473-00228735-00229378": "SCP-423 will become an inanimate object in the story instead, though still aware of events", "cgJbCtRG1lY-00474-00229378-00229478": "occuring.", "cgJbCtRG1lY-00475-00229478-00229871": "Date: ██/██/████ Test Material: The lyrics to \"Bohemian Rhapsody\",", "cgJbCtRG1lY-00476-00229871-00229971": "by Queen", "cgJbCtRG1lY-00477-00229971-00230785": "Result: In verses 2 and 3, \"mama\" was replaced by \"Frederica\". SCP-423 seemed unaware that", "cgJbCtRG1lY-00478-00230785-00231542": "this was a song as opposed to a poem. It seems that not all information is given to SCP-423,", "cgJbCtRG1lY-00479-00231542-00232015": "merely enough for him to not interrupt the flow of a poem or song, as well as fulfill", "cgJbCtRG1lY-00480-00232015-00232271": "any standards set by a story.", "cgJbCtRG1lY-00481-00232271-00232766": "Date: ██/██/████ Test Material: 50 Shades of Grey, by E.L.", "cgJbCtRG1lY-00482-00232766-00232866": "James", "cgJbCtRG1lY-00483-00232866-00233477": "Result: A minor character \"Fred\" appeared in the background. SCP-423 expressed that", "cgJbCtRG1lY-00484-00233477-00233892": "it was a bit uncomfortable with the explicit scenes within the book and requests that it", "cgJbCtRG1lY-00485-00233892-00234267": "be sent to stories with more adventure and action next time.", "cgJbCtRG1lY-00486-00234267-00234895": "Notes: It seems that SCP-423 also has a taste for specific books; this is the first time", "cgJbCtRG1lY-00487-00234895-00235375": "it was exposed to a sexually explicit book, so it was not used to the situation.", "cgJbCtRG1lY-00488-00235375-00235900": "Date: ██/██/████ Test Material: \"This is the title of this", "cgJbCtRG1lY-00489-00235900-00236411": "story, which is also found several times in the story itself\", by David Moser, a metafictional", "cgJbCtRG1lY-00490-00236411-00236547": "story about self-reference.", "cgJbCtRG1lY-00491-00236547-00237179": "Result: Several additional sentences appear throughout the story, including \"This is the", "cgJbCtRG1lY-00492-00237179-00237669": "sentence in which Fred appears\", \"This is not the sentence in which Fred appears\", and", "cgJbCtRG1lY-00493-00237669-00238121": "\"This sentence alludes to Fred's presence but does not actually contain Fred\".", "cgJbCtRG1lY-00494-00238121-00238590": "Date: ██/██/████ Test Material: Written by Doctor X██,", "cgJbCtRG1lY-00495-00238590-00239065": "a list of 100 fictional people doing things simultaneously in different areas, with a", "cgJbCtRG1lY-00496-00239065-00239534": "tragic end, along with a final over-encompassing statement about each of them contributing", "cgJbCtRG1lY-00497-00239534-00239698": "to the tragedy.", "cgJbCtRG1lY-00498-00239698-00240361": "Result: This test was to determine if there was an upper-limit to how many locations SCP-423", "cgJbCtRG1lY-00499-00240361-00240935": "could reside in at the same time within a book. Out of 100 fictional people, only 83", "cgJbCtRG1lY-00500-00240935-00241619": "had the mention of \"Fred\" with it. The tragedy was not prevented in the end. SCP-423 noted", "cgJbCtRG1lY-00501-00241619-00242121": "that it got too tired after being in 83 different places in the story.", "cgJbCtRG1lY-00502-00242121-00242569": "Date: ██/██/████ Test Material: The file for SCP-055", "cgJbCtRG1lY-00503-00242569-00243239": "Result: Inconclusive, SCP-423 stated it was not sure what it was doing other than the", "cgJbCtRG1lY-00504-00243239-00243895": "fact that something was not spherical. Researchers soon forgot what they sent SCP-423 to do.", "cgJbCtRG1lY-00505-00243895-00244451": "Date: ██/██/████ Test Material: The experimental data for SCP-2719", "cgJbCtRG1lY-00506-00244451-00245148": "(labeled \"SCP-2719\") with no outcomes listed, and with an additional entry with \"SCP-423\"", "cgJbCtRG1lY-00507-00245148-00245489": "at the bottom, also with no outcome listed.", "cgJbCtRG1lY-00508-00245489-00246371": "Result: The data was filled precisely identical to the real file of SCP-2719. SCP-423's outcome", "cgJbCtRG1lY-00509-00246371-00247046": "was \"became inside\". When questioned, SCP-423 responded that it merely observed what occurred", "cgJbCtRG1lY-00510-00247046-00247739": "with each entity, despite SCP-2719 being an abstract metaphysical concept. It also somehow", "cgJbCtRG1lY-00511-00247739-00248416": "experienced becoming inside, despite having no knowledge of 2719. More testing to be done", "cgJbCtRG1lY-00512-00248416-00249023": "with 2719 and 423. Notes: It seems that abstract entities manifesting", "cgJbCtRG1lY-00513-00249023-00249697": "themselves have the same effect on SCP-423 as any usual person, even if SCP-423 has no", "cgJbCtRG1lY-00514-00249697-00250281": "idea what is happening. It also seems it can fill in the blanks based on what already happened.", "cgJbCtRG1lY-00515-00250281-00250854": "Date: ██/██/████ Test Material: Experiment Log 914 - Part II", "cgJbCtRG1lY-00516-00250854-00251469": "Result: A record appeared in Test Logs, Part 8 of an experiment performed by \"Guest Researcher", "cgJbCtRG1lY-00517-00251469-00251904": "Fred\", with the rest of the data for said experiment blocked out.", "cgJbCtRG1lY-00518-00251904-00252195": "Date: TOTAL_DATE_FAILURE", "cgJbCtRG1lY-00519-00252195-00253115": "Test Material: The Abridged History of Homo Sapiens by History Analysis Subroutine #7589372357286473-NFIZ", "cgJbCtRG1lY-00520-00253115-00254277": "Results: SCP-423 is featured under the \"unknown periods\" section as a featureless humanoid", "cgJbCtRG1lY-00521-00254277-00254896": "screaming in a infinite white void and rambling incoherently. After being returned SCP-423", "cgJbCtRG1lY-00522-00254896-00255402": "showed signs on prolonged exposure to weak-time suggesting that SCP-423 still understands", "cgJbCtRG1lY-00523-00255402-00255742": "temporal physics in a manner similar to organic beings.", "cgJbCtRG1lY-00524-00255742-00255919": "javascript:; Date: ██/██/████", "cgJbCtRG1lY-00525-00255919-00256520": "Test Material: An untitled 50,000 page \"story\" created by randomization bound by grammar", "cgJbCtRG1lY-00526-00256520-00256776": "and basic sentence structure created for this test.", "cgJbCtRG1lY-00527-00256776-00257474": "Result: The sentence \"Joshua went to the diagonal party without his safety ants.\" was replaced", "cgJbCtRG1lY-00528-00257474-00257906": "with \"Joshua went to the diagonal party without his safety Fred.\"", "cgJbCtRG1lY-00529-00257906-00258507": "Notes: SCP-423 noted that being in the document was similar to when it has experienced dreams", "cgJbCtRG1lY-00530-00258507-00258794": "in other stories which it slept.", "cgJbCtRG1lY-00531-00258794-00259177": "Date: ██/██/████ Test Material: A printout of the gamescript", "cgJbCtRG1lY-00532-00259177-00259678": "for \"The Secret of Monkey Island\". Result was laser-scanned and the raw text compiled", "cgJbCtRG1lY-00533-00259678-00260034": "into a working program after being screened for anomalies.", "cgJbCtRG1lY-00534-00260034-00260640": "Results: An NPC named Fred appears near the small building at the pier on Melee Island.", "cgJbCtRG1lY-00535-00260640-00261194": "When spoken to, the player is presented with a dialogue tree. Questioning him on his backstory", "cgJbCtRG1lY-00536-00261194-00261667": "reveals that he tried and failed to become a pirate. It is mandatory to recruit him on", "cgJbCtRG1lY-00537-00261667-00262185": "the ship's crew for the second chapter, where he joins the mutiny. Subsequent cutscenes", "cgJbCtRG1lY-00538-00262185-00262452": "have him present with the rest of the crew.", "cgJbCtRG1lY-00539-00262452-00263083": "Notes: Upon returning to the journal, SCP-423 remarked \"That was like a choose-your-own-adventure", "cgJbCtRG1lY-00540-00263083-00263349": "book. Let me know if you find any more.\"", "cgJbCtRG1lY-00541-00263349-00263875": "Date: ██/██/████ Test Material: A Million Random Digits with", "cgJbCtRG1lY-00542-00263875-00264459": "100,000 Normal Deviates (published by Rand Corporation, 1955)", "cgJbCtRG1lY-00543-00264459-00265063": "Result: Addition of a preface by Dr. Frederick McCarthy, explaining the statistical methodology", "cgJbCtRG1lY-00544-00265063-00265300": "used to generate the numbers in the book.", "cgJbCtRG1lY-00545-00265300-00265818": "Date: ██/██/████ Test Material: The \"Location, Location, Location\"", "cgJbCtRG1lY-00546-00265818-00266339": "story arc from the first print collection of \"Precocious\". Precocious is a webcomic", "cgJbCtRG1lY-00547-00266339-00266844": "where all characters are anthropomorphic animals. However, none of the dialogue in this particular", "cgJbCtRG1lY-00548-00266844-00267550": "story states or implies a species. The purpose of the test is to determine if SCP-423 can", "cgJbCtRG1lY-00549-00267550-00267757": "\"sense\" artwork.", "cgJbCtRG1lY-00550-00267757-00268224": "Results: Mr. Crupp states the name of the father in an offscreen family to be named", "cgJbCtRG1lY-00551-00268224-00268952": "Fred. Upon returning to the journal, SCP-423 was asked if the cast of this story were human.", "cgJbCtRG1lY-00552-00268952-00269535": "SCP-423 states that they were animals, and he himself took on the form of an arctic fox.", "cgJbCtRG1lY-00553-00269535-00269903": "Further questioning reveals that this was the most nondescript species of the choices", "cgJbCtRG1lY-00554-00269903-00270070": "he was given.", "cgJbCtRG1lY-00555-00270070-00270455": "Date: ██/██/████ Test Material: The entire script of William", "cgJbCtRG1lY-00556-00270455-00270667": "Shakespeare's Hamlet.", "cgJbCtRG1lY-00557-00270667-00271180": "Results: During Act 1, Scene 2, a character by the name of \"Frederick\" sneezes halfway", "cgJbCtRG1lY-00558-00271180-00271780": "through King Claudius' speech. Hamlet laughs. No other changes has been discovered.", "cgJbCtRG1lY-00559-00271780-00272378": "Notes: When questioned, SCP-423 stated \"I got a little bored during the speech,\".", "cgJbCtRG1lY-00560-00272378-00272966": "Date: ██/██/████ Test Material: SCP-1459 Extended Testing Log", "cgJbCtRG1lY-00561-00272966-00273179": "Results: No change.", "cgJbCtRG1lY-00562-00273179-00276452": "Notes: SCP-423 stated the following: \"You all disgust me. So. Fucking. Much.\""}}, {"audio_id": "cgPDbeZ1Km0", "text": {"cgPDbeZ1Km0-00000-00000035-00000624": "Thank you, Madame President. Colleagues, I rise in support of Senate Bill 52, which", "cgPDbeZ1Km0-00001-00000624-00001128": "comes from your Senate Education Committee on a 5-0 vote. It's known as", "cgPDbeZ1Km0-00002-00001128-00001650": "Adi's Act, and ensures that every school district in the state of Oregon puts in", "cgPDbeZ1Km0-00003-00001650-00002367": "place a comprehensive suicide prevention policy and plan. We are in a crisis in", "cgPDbeZ1Km0-00004-00002367-00003000": "Oregon. Every three days on average, we lose a young person to suicide. The", "cgPDbeZ1Km0-00005-00003000-00003642": "statistics speak for themselves. Suicide is now the second leading cause", "cgPDbeZ1Km0-00006-00003642-00004448": "of death for Oregon youth, and tragically it is on the rise. Regarding this bill,", "cgPDbeZ1Km0-00007-00004448-00005001": "Oregon is one of three states without a statutory requirement for schools to", "cgPDbeZ1Km0-00008-00005001-00005705": "have suicide prevention plans in place. We know that local examples exist: Lines", "cgPDbeZ1Km0-00009-00005705-00006401": "for Life partnering with the Willamette ESD have resources that aim to reduce youth", "cgPDbeZ1Km0-00010-00006401-00006942": "suicide and build awareness for mental health and wellness. The bill itself does", "cgPDbeZ1Km0-00011-00006942-00007431": "have an emergency clause, and it allows the Department of Education the", "cgPDbeZ1Km0-00012-00007431-00007984": "opportunity to work on notification to school districts of this policy change.", "cgPDbeZ1Km0-00013-00007984-00008565": "However, the requirement for plans will not have to be formally adopted until", "cgPDbeZ1Km0-00014-00008565-00009357": "the 2020-2021 school calendar year. The School Boards Association supports the", "cgPDbeZ1Km0-00015-00009357-00010031": "bill, and I do not believe we can wait one more day to begin this work. In", "cgPDbeZ1Km0-00016-00010031-00010418": "committee, there was some good conversation about the need for", "cgPDbeZ1Km0-00017-00010418-00011140": "specifying attention to certain specific student populations, and let me be clear,", "cgPDbeZ1Km0-00018-00011140-00011571": "the plans that school districts would adopt would impact and address the needs", "cgPDbeZ1Km0-00019-00011571-00012365": "of all students. But the data is also clear that certain populations are at", "cgPDbeZ1Km0-00020-00012365-00013052": "even higher risk. This includes youth bereaved by suicide,", "cgPDbeZ1Km0-00021-00013052-00013562": "with disabilities, mental illness, substance use disorders, youth", "cgPDbeZ1Km0-00022-00013562-00014590": "experiencing homelessness, or in foster care, and our LGBTQ youth. Nearly half of", "cgPDbeZ1Km0-00023-00014590-00015302": "LGBTQ eighth graders have contemplated suicide. It's three times the general", "cgPDbeZ1Km0-00024-00015302-00016247": "population, and almost 1/3 of transgender eighth graders have attempted suicide. As", "cgPDbeZ1Km0-00025-00016247-00016715": "we know in this building, behind every statistic is a story. Behind these", "cgPDbeZ1Km0-00026-00016715-00017423": "statistics are too many youth who have been lost in this tragic struggle. In", "cgPDbeZ1Km0-00027-00017423-00017990": "committee we heard from the parents of Chloe Wilson, a teenager who struggled", "cgPDbeZ1Km0-00028-00017990-00018374": "with mental health, and in fact she testified in the Oregon Legislature a", "cgPDbeZ1Km0-00029-00018374-00018770": "year before her death about the need to have increased mental health supports in", "cgPDbeZ1Km0-00030-00018770-00019451": "our schools. We also heard from Lon and Christine Staub about their daughter", "cgPDbeZ1Km0-00031-00019451-00020102": "Adi. They're joining us today in the gallery. I want to thank them for their", "cgPDbeZ1Km0-00032-00020102-00020675": "willingness to share Adi's story, despite their heartache and their", "cgPDbeZ1Km0-00033-00020675-00021188": "courage to help us make this change. I want to share some of their testimony", "cgPDbeZ1Km0-00034-00021188-00021709": "here because I believe it is important that we learned from their experience.", "cgPDbeZ1Km0-00035-00021709-00022181": "Adi Staub came out as a transgender girl after her sophomore year in high", "cgPDbeZ1Km0-00036-00022181-00022997": "school. Her parents tell us she was excited for her future which gave her", "cgPDbeZ1Km0-00037-00022997-00023660": "courage to bravely share her truth to her classmates and her communities. When", "cgPDbeZ1Km0-00038-00023660-00023999": "she returned to school she found that some friends and teachers accepted her", "cgPDbeZ1Km0-00039-00023999-00024491": "and generally cared for her well-being. However, there were many more classmates", "cgPDbeZ1Km0-00040-00024491-00025069": "and teachers who misgendered and misnamed her, sometimes intentionally and", "cgPDbeZ1Km0-00041-00025069-00025608": "repeatedly. She experienced the crushing loss of friendships and felt", "cgPDbeZ1Km0-00042-00025608-00026405": "marginalized. After being a straight A student, Adi failed in school.", "cgPDbeZ1Km0-00043-00026405-00026875": "With each act of aggression or ambivalence, she lost more and more hope", "cgPDbeZ1Km0-00044-00026875-00027337": "and fell into depression, until 18 months ago just two years after her joyful", "cgPDbeZ1Km0-00045-00027337-00028127": "transition, Adi took her own life. In this state this session we're working on", "cgPDbeZ1Km0-00046-00028127-00028597": "comprehensive efforts to address suicide prevention, including interagency", "cgPDbeZ1Km0-00047-00028597-00029115": "coordination -- We'll hear from Senator Gelser and Senate Bill 485 today, and", "cgPDbeZ1Km0-00048-00029115-00029550": "resources and supports for school districts to promote Safe Schools, and", "cgPDbeZ1Km0-00049-00029550-00029980": "bipartisan efforts to tackle bullying and harassment.", "cgPDbeZ1Km0-00050-00029980-00030569": "Senate Bill 52 is part of that vital conversation, and an important step", "cgPDbeZ1Km0-00051-00030569-00031327": "forward, but not our only step in preventing youth suicide. Today I ask for", "cgPDbeZ1Km0-00052-00031327-00031894": "your support for Adi's Act, to work to save lives and assure that all kids see", "cgPDbeZ1Km0-00053-00031894-00033044": "a future for themselves in Oregon. I just wanted to thank the Staub family and the", "cgPDbeZ1Km0-00054-00033044-00033721": "hundreds of parents that share their grief and their struggle in order to", "cgPDbeZ1Km0-00055-00033721-00034958": "help us understand the need for Public Policy. We stand with you, ready to help", "cgPDbeZ1Km0-00056-00034958-00035688": "make a difference in the lives of young people in our state. Thank you."}}, {"audio_id": "chiWVxRmxtI", "text": {"chiWVxRmxtI-00000-00000003-00000238": "Hey guys and welcome back to my channel!", "chiWVxRmxtI-00001-00000238-00000342": "It's Miss Kay Krizz", "chiWVxRmxtI-00002-00000342-00000930": "and today we're gonna continue on with Q&A series for cabin crew interviews.", "chiWVxRmxtI-00003-00001064-00001502": "Today's question is a really tricky one so make sure that you stay tuned for it.", "chiWVxRmxtI-00006-00002510-00003057": "Today's question, were going to answer the question -- it's a little bit personal", "chiWVxRmxtI-00007-00003057-00003306": "and it's not really common.", "chiWVxRmxtI-00008-00003306-00003878": "It really is usually asked of you if you reach the final stages of the interview", "chiWVxRmxtI-00009-00003878-00004452": "The question is: \"Do you think you will find a change in lifestyle difficult to adapt to", "chiWVxRmxtI-00010-00004460-00004856": "if you are successful in becoming a member of our cabin crew team?\"", "chiWVxRmxtI-00011-00005036-00005665": "There is only one way to answer this question which is: \"NO. It will not be difficult for you", "chiWVxRmxtI-00012-00005666-00005848": "to adjust to the lifestyle.\"", "chiWVxRmxtI-00013-00005958-00006518": "When answering this nature of question, tell them that  you have researched the role well", "chiWVxRmxtI-00014-00006518-00007304": "and are fully aware of the different implications including the change of lifestyle that it will bring.", "chiWVxRmxtI-00015-00007430-00007968": "Also remember to touch on specifics about the change in lifestyle and what it means to you", "chiWVxRmxtI-00016-00007968-00008502": "and how you have prepared for it. Don't be afraid to say that some areas", "chiWVxRmxtI-00017-00008502-00008934": "will be a challenge for you or difficult for you but you are fully committed and", "chiWVxRmxtI-00018-00008934-00009350": "prepared for everything that the job presents.", "chiWVxRmxtI-00019-00009486-00009954": "The key is to consider is make sure that you smile and you are enthusiastic", "chiWVxRmxtI-00020-00009954-00010260": "when you are answering this question.", "chiWVxRmxtI-00021-00010260-00010632": "Talk about the change in lifestyle for you and how you have", "chiWVxRmxtI-00022-00010632-00011183": "prepared for it personally and you have thought a long and hard", "chiWVxRmxtI-00023-00011183-00011988": "when you are considering this career and your personal circumstances that is suited for this role.", "chiWVxRmxtI-00024-00011988-00012286": "Now, let's go to the sample answer:", "chiWVxRmxtI-00025-00012458-00012944": "\"No. When I took up tourism, we trained that in the future we need to be flexible", "chiWVxRmxtI-00026-00012944-00013402": "and that in any time the work needs us, we should be there no matter what.", "chiWVxRmxtI-00027-00013402-00014054": "Even then, we did our internship outside the country to ensure that we are able to acquire the", "chiWVxRmxtI-00028-00014054-00014628": "skills of adapting to a new environment and getting out of our comfort zone.", "chiWVxRmxtI-00029-00014628-00015233": "In my experience, I quite like the change of environment and the learning of the new", "chiWVxRmxtI-00030-00015233-00015752": "skills that I will learn when I interact with different people, different project", "chiWVxRmxtI-00031-00015752-00016030": "demands and a new physical location.", "chiWVxRmxtI-00032-00016030-00016337": "As a cabin crew aspirant, I am fully aware of", "chiWVxRmxtI-00033-00016337-00016804": "the implications including the change of lifestyle that it will bring", "chiWVxRmxtI-00034-00016804-00017330": "specifically, the different time zones that you have to work into the different", "chiWVxRmxtI-00035-00017330-00017933": "sleeping schedules that I have to adapt to and also the different cultures of", "chiWVxRmxtI-00036-00017933-00018410": "the crew members which are going to be coming from different countries", "chiWVxRmxtI-00037-00018410-00018698": "because it is an international airline.", "chiWVxRmxtI-00038-00018698-00019282": "I have fully researched this lifestyle and I think I am really prepared", "chiWVxRmxtI-00039-00019282-00019826": "and I am preparing myself, mentally, physically, and emotionally on how I would be adapting to it", "chiWVxRmxtI-00040-00019826-00020056": "once I become a successful cabin crew member.\"", "chiWVxRmxtI-00041-00020258-00020428": "So that's how you will answer it.", "chiWVxRmxtI-00042-00020428-00020886": "Make sure that you touch on different specifics of the cabin crew lifestyle", "chiWVxRmxtI-00043-00020886-00021116": "specially the change in sleeping pattern,", "chiWVxRmxtI-00044-00021116-00021601": "the different working schedules. the different lengths of time that you have", "chiWVxRmxtI-00045-00021601-00022061": "to be in the airplane, the different destinations that you have to go through,", "chiWVxRmxtI-00046-00022061-00022216": "and things like that.", "chiWVxRmxtI-00047-00022216-00022500": "So always, always be positive about it.", "chiWVxRmxtI-00048-00022500-00023126": "Look at it as a challenge that you are willing to take on and you are excited to do.", "chiWVxRmxtI-00049-00023126-00023518": "and for you to grow personally and professionally as well.", "chiWVxRmxtI-00050-00023662-00024518": "So if you want to see more different cabin crew questions and sample on how I will answer them,", "chiWVxRmxtI-00051-00024518-00024842": "make sure that you download the PDF file of this series.", "chiWVxRmxtI-00052-00024842-00025204": "It's on my website at misskaykrizz.com.", "chiWVxRmxtI-00053-00025204-00025504": "It's completely free of charge, so don't worry about that.", "chiWVxRmxtI-00054-00025764-00026062": "I just want you guys to be prepared as much as possible.", "chiWVxRmxtI-00055-00026062-00026574": "So go ahead and study and do your research and good luck on your application!", "chiWVxRmxtI-00056-00026574-00026789": "and I will fly with you soon, bye!"}}, {"audio_id": "chkdksXc5xI", "text": {"chkdksXc5xI-00000-00000566-00000956": "I would suggest you draw lashes after you get familiar with drawing eyes in detail.", "chkdksXc5xI-00001-00001019-00001220": "Center the front of the face.", "chkdksXc5xI-00002-00001226-00001590": "Then divide the direction of lashes from right to left of the baseline.", "chkdksXc5xI-00003-00001626-00001980": "It is the same for the lower lashes.", "chkdksXc5xI-00004-00002490-00002763": "Tab the roots outside of the mucous membrane.", "chkdksXc5xI-00005-00002763-00002986": "Then extend it beyond the double eyelid.", "chkdksXc5xI-00006-00003210-00003563": "Eyelash root should be thicker than eyelash edge.", "chkdksXc5xI-00007-00003710-00004113": "Draw with some gaps not too close.", "chkdksXc5xI-00008-00004113-00004616": "The center where the right and left of lashes’ angle should be drawn as close as the straight line.", "chkdksXc5xI-00009-00004653-00005236": "Don’t think that you must draw lashes only with curves.", "chkdksXc5xI-00010-00005330-00005893": "No need to draw lashes at once in one stroke.", "chkdksXc5xI-00011-00005933-00006323": "Usually, I draw it all at once.", "chkdksXc5xI-00012-00006323-00006993": "But the painting which the eyes especially should be stressed, I draw it one by one several times.", "chkdksXc5xI-00013-00007596-00008190": "Draw it lying down so that it spreads out.", "chkdksXc5xI-00014-00008540-00008800": "In my case, I begin from the eyeline outside the waterline.", "chkdksXc5xI-00015-00008800-00009060": "Then finish over the double eyelid.", "chkdksXc5xI-00016-00009143-00009343": "In case of the lower lashes, draw the outer lines", "chkdksXc5xI-00017-00009343-00009736": "not the mucous membrane.", "chkdksXc5xI-00018-00009823-00010023": "Check the front.", "chkdksXc5xI-00019-00010063-00010326": "Then draw it not too over the length of aegyo-sal (eye bags)", "chkdksXc5xI-00020-00010360-00010723": "Root thicker, edge thinner.", "chkdksXc5xI-00021-00011443-00011900": "And draw lower lashes much thinner than upper lashes.", "chkdksXc5xI-00022-00011940-00012420": "If You draw bind 2 strands, you can express more naturally.", "chkdksXc5xI-00023-00012536-00013143": "My tip is that don’t make eyelashes out.", "chkdksXc5xI-00024-00013906-00014106": "After you draw all, make the size of brush bigger.", "chkdksXc5xI-00025-00014136-00014586": "Then touch eyelash root one more time.", "chkdksXc5xI-00026-00014740-00015116": "If you were worried that eyelashes would look far from the face.", "chkdksXc5xI-00027-00015156-00015723": "Try to thicken the thickness of root and whole lashes.", "chkdksXc5xI-00028-00015773-00016250": "You would feel more different and natural.", "chkdksXc5xI-00029-00016456-00017056": "Add lashes as thin as lower lashes between the upper lashes I drew at first.", "chkdksXc5xI-00030-00018046-00018576": "No matter what angle you draw, as long as the center is perfect, it’s not a problem.", "chkdksXc5xI-00031-00020260-00020906": "Don’t think that you should draw straight lashes on the other eye as well.", "chkdksXc5xI-00032-00022226-00022386": "Here is another tip.", "chkdksXc5xI-00033-00022406-00022916": "At the eye wing, draw as if the upper and lower lashes almost meet.", "chkdksXc5xI-00034-00022916-00023366": "The angle of the lashes gets closer to the horizontal as almost close the edge of the eye.", "chkdksXc5xI-00035-00023390-00023856": "Sometimes it meets each other at the corners of the eye wing.", "chkdksXc5xI-00036-00024210-00024616": "That’s it for the eyelash drawing today.", "chkdksXc5xI-00037-00024643-00025146": "If you draw the small face, try drawing less hair than now.", "chkdksXc5xI-00038-00025250-00025706": "Draw eye shadow and light then done.", "chkdksXc5xI-00039-00025739-00026296": "Please check the last video about coloring of the pupil.", "chkdksXc5xI-00040-00026336-00027223": "Check out Class 101 for more drawing tips, including front-angle eyelashes!", "chkdksXc5xI-00041-00027296-00027743": "See you next video. 😚"}}, {"audio_id": "chHmELAr2kE", "text": {"chHmELAr2kE-00000-00000000-00001100": "\"Se terminó Intrusos, este tipo termina de hundir el programa\": el video de un corte televisivo en América TV", "chHmELAr2kE-00001-00001200-00002200": "Este miércoles en Intrusos estuvieron Los Midachi como invitados.", "chHmELAr2kE-00002-00002300-00003300": "Y durante un corte para ir a publicidades, salió el tema del reemplazo de Jorge Rial.", "chHmELAr2kE-00003-00003400-00004400": "Ante los rumores, le consultaron a Dady Brieva.", "chHmELAr2kE-00004-00004500-00005500": "Y los televidentes están que braman.", "chHmELAr2kE-00005-00005600-00007800": "Recientemente, Jorge Rial sorprendió a todos al anunciar tras un viaje a Estados Unidos que se tomaría una licencia por algunos meses de 18 años, el programa de espectáculos más longevo de la televisión argentina.", "chHmELAr2kE-00006-00007900-00008900": "Fue Moria Casán quien desde entonces se hizo cargo del programa.", "chHmELAr2kE-00007-00009000-00010000": "Aunque ahora, hay rumores de que se analiza reemplazarla.", "chHmELAr2kE-00008-00010100-00011500": "Jorge Rial dio un paso al costado, al menos de momento, de su programa y justamente hoy anunció que regresaría en octubre al ciclo.", "chHmELAr2kE-00009-00011600-00012600": "Por ahora, Intrusos quedó a cargo de Moria Casán.", "chHmELAr2kE-00010-00012700-00014800": "Sin embargo, pronto ocuparía ese lugar Dady Brieva, que está en tratativas con el canal para conducir el ciclo hasta que se reintegre el conductor, que se espera, sea a fines de este año o principios del que viene.", "chHmELAr2kE-00011-00014900-00015900": "Curiosamente, justo hoy estuvo el Midachi a Intrusos.", "chHmELAr2kE-00012-00016000-00017000": "Y desde la cuenta oficial del programa en Twitter pusieron un video de uno de los cortes del programa.", "chHmELAr2kE-00013-00017100-00018200": "Allí se ve a Dady, Moria y otros \"Intrusos\" mientras hablan de la posibilidad de que Dady conduzca el histórico ciclo.", "chHmELAr2kE-00014-00018300-00019300": "Y al parecer, no cayó bien el video entre los televidentes.", "chHmELAr2kE-00015-00019400-00020400": "\"Se termino @Intrusos  ,este tipo termina de hundir el programa\", comentó un usuario.", "chHmELAr2kE-00016-00020500-00021500": "\"Que asco este tipo y la cara de boludoooo impresentable\",.", "chHmELAr2kE-00017-00021600-00023700": "\"Lo que le faltaria para ser el titanic\" y \"Nah conduce este chabon y dejo de ver el programa! Tiniendo sushi todos los dias me van a dar choriplanero? Los dejo eh\", fueron otros de los comentarios."}}, {"audio_id": "chMFYbutxJg", "text": {"chMFYbutxJg-00000-00000145-00000411": "Let's see if I can do it, you ready?", "chMFYbutxJg-00001-00000411-00000790": "Ok, we're here, at Wasabi-con 2017.", "chMFYbutxJg-00002-00000790-00001080": "Located in the wondrous Jacksonville, Florida.", "chMFYbutxJg-00003-00001080-00001942": "Italy has just had a drink of spiked pasta sauce, it doesn't take much to get him going.", "chMFYbutxJg-00004-00001942-00002138": "And this is what he says.", "chMFYbutxJg-00005-00002138-00002478": "ITALY: Alright, I’ve got a bone to pick with everyone in this room, so everyone just", "chMFYbutxJg-00006-00002478-00002694": "shut up and listen!", "chMFYbutxJg-00007-00002694-00002794": "ITALY: I’ll start with mio fratello here.", "chMFYbutxJg-00008-00002794-00002950": "ITALY: I want to know why you’re so *hiccup* angry all the time!", "chMFYbutxJg-00009-00002950-00003358": "ITALY: You’ve had Spain taking care of you your whole life with a smile and yet you’ve", "chMFYbutxJg-00010-00003358-00003500": "got the meatballs to curse at him and take him for *hiccup* granted!", "chMFYbutxJg-00011-00003500-00003888": "ITALY: He’s stayed by your side no matter how many times you crush his vital regions", "chMFYbutxJg-00012-00003888-00003978": "to wake him up!", "chMFYbutxJg-00013-00003978-00004044": "Who the hell even does that!?", "chMFYbutxJg-00014-00004047-00004252": "ITALY: Dios mio, Prussia!", "chMFYbutxJg-00015-00004252-00004470": "ITALY: Stop telling everyone how *hiccup* “awesome” you are!", "chMFYbutxJg-00016-00004470-00004564": "ITALY: Just shut up in general!", "chMFYbutxJg-00017-00004570-00004888": "Are you so insecure that you boast about your own hype just to feel like a *hiccup* man?!", "chMFYbutxJg-00018-00004888-00004982": "ITALY: News-flash!", "chMFYbutxJg-00019-00004982-00005250": "Your milkshake is what everyone gets sick of because it’s expired!", "chMFYbutxJg-00020-00005258-00005350": "ITALY: Japan!", "chMFYbutxJg-00021-00005456-00005668": "ITALY: Learn to *hiccup* smile more often!", "chMFYbutxJg-00022-00005676-00005862": "Are you even capable of smiling?", "chMFYbutxJg-00023-00005876-00005984": "Cheer up, thing’s aren’t so bad!", "chMFYbutxJg-00024-00006030-00006150": "ITALY: And you!", "chMFYbutxJg-00025-00006160-00006298": "Germany!", "chMFYbutxJg-00026-00006308-00006536": "ITALY: We all know why you’re so uptight and why you like to yell at everyone!", "chMFYbutxJg-00027-00006536-00006758": "ITALY: It’s because you don’t get *hiccup* laid enough!", "chMFYbutxJg-00028-00006758-00006873": "(That's a good point).", "chMFYbutxJg-00029-00006931-00007138": "ITALY: I’ve seen what’s in the secret box in your closet!", "chMFYbutxJg-00030-00007162-00007395": "I had to go to a confessional after that nightmare!", "chMFYbutxJg-00031-00007412-00007880": "ITALY: Either go get a lady of the night or you can *hiccup* yourself!", "chMFYbutxJg-00032-00007890-00008000": "ITALY: And another thing!", "chMFYbutxJg-00033-00008008-00008102": "ITALY: Who are you calling drunk?", "chMFYbutxJg-00034-00008102-00008152": "[Pause briefly]", "chMFYbutxJg-00035-00008152-00008466": "ITALY: You’re not drunk, I’m drunk!", "chMFYbutxJg-00036-00008467-00008517": "(Italy passes out) *Snore*"}}, {"audio_id": "cikb2AXSw_o", "text": {"cikb2AXSw_o-00000-00000000-00000200": "I had noticed that the algorithm changed on the video."}}, {"audio_id": "cixrGwm7G6y", "text": {"cixrGwm7G6y-00000-00000235-00000810": "Another effective digitally station is the possibility to undertake extensive surveillance.", "cixrGwm7G6y-00001-00000810-00001415": "When people say that the digital age we live in a digital panopticon.", "cixrGwm7G6y-00002-00001415-00001779": "Panopticon where everybody can be seen as the idea of having a prism.", "cixrGwm7G6y-00003-00001779-00002387": "For example, where a single watchman can watch hundreds of prison inmates without them knowing", "cixrGwm7G6y-00004-00002387-00002685": "when or if they are being watched.", "cixrGwm7G6y-00005-00002685-00003204": "So so this is this kind of reference and this is a very long debate.", "cixrGwm7G6y-00006-00003204-00003732": "In the first vision of the information age of information society actually does not come", "cixrGwm7G6y-00007-00003732-00003994": "from an academic or entrepreneurial policy maker.", "cixrGwm7G6y-00008-00003994-00004264": "It comes from a novelist.", "cixrGwm7G6y-00009-00004264-00005055": "In 1948, the novelist George Orwell wrote a book that she called 1984 in which he describes", "cixrGwm7G6y-00010-00005055-00005797": "future society in which a mix of government and private corporations rose up and saw themselves", "cixrGwm7G6y-00011-00005797-00006376": "as the “guardian of democracy” and they used informational means and information technology", "cixrGwm7G6y-00012-00006376-00006658": "back in the days they weren’t digital yet.", "cixrGwm7G6y-00013-00006658-00007268": "In order to safeguard democracy in the society.", "cixrGwm7G6y-00014-00007268-00007903": "The result of that being in this book that has drawn over puts it by comparison with", "cixrGwm7G6y-00015-00007903-00008339": "that existing today, all the tyrannies of the past were half-hearted and inefficient", "cixrGwm7G6y-00016-00008339-00009160": "because a complete informational controller attorney could lead to much more effective", "cixrGwm7G6y-00017-00009160-00009281": "control and surveillance.", "cixrGwm7G6y-00018-00009281-00009735": "For example, the phrase, “big brother is watching you” comes from this book.", "cixrGwm7G6y-00019-00009735-00010253": "So big brother that’s what the surveillance machinery was caught and nowadays we have", "cixrGwm7G6y-00020-00010253-00010875": "of course a very hotly debated discussion about the right balance between privacy and", "cixrGwm7G6y-00021-00010875-00011518": "surveillance and the safeguarding especially of security against attacks against terrorist", "cixrGwm7G6y-00022-00011518-00011835": "attacks especially after 911.", "cixrGwm7G6y-00023-00011835-00012457": "Many security agencies in the United States intelligence services rose up and embrace", "cixrGwm7G6y-00024-00012457-00012905": "digital technologies in order to intensify their surveillance.", "cixrGwm7G6y-00025-00012905-00013519": "For example, it has been revealed by Edward Snowden, the National Security Agency for", "cixrGwm7G6y-00026-00013519-00013977": "seven years undertook a bulk collection of all American phone records.", "cixrGwm7G6y-00027-00013977-00014566": "It means it was recorded one American called another one for seven years completely but", "cixrGwm7G6y-00028-00014566-00015228": "the justification being that this might help the NSA to prevent future terrorist attacks.", "cixrGwm7G6y-00029-00015228-00015833": "Now after these revelations, that deputy director of the NSA was asked how many terrorist attacks", "cixrGwm7G6y-00030-00015833-00016454": "they could successfully prevent based on this insight and he said well that it might’ve", "cixrGwm7G6y-00031-00016454-00017044": "maybe helped them to stop one San Diego taxi driver from sending a few thousand dollars", "cixrGwm7G6y-00032-00017044-00017730": "to a terrorist group in Somalia and they said well something else they said, “not really,", "cixrGwm7G6y-00033-00017730-00018311": "no” and so many people were really outraged at seven years, a really profound intrusion", "cixrGwm7G6y-00034-00018311-00019033": "of people’s privacy for maybe preventing a taxi driver sending a few thousand dollars.", "cixrGwm7G6y-00035-00019033-00019593": "So the right balance between privacy intrusions simply because it’s digitally possible simply", "cixrGwm7G6y-00036-00019593-00019998": "because we can live, we do live in a digital panopticon business as possible.", "cixrGwm7G6y-00037-00019998-00020445": "The fact that we should also do that and where’s the right balance between giving up your privacy", "cixrGwm7G6y-00038-00020445-00020612": "and strengthening security.", "cixrGwm7G6y-00039-00020612-00021442": "This is really an open debate and um everybody is welcome to join at this point.", "cixrGwm7G6y-00040-00021442-00022034": "So called whistleblowing is another result combination of several characteristic of digitalization", "cixrGwm7G6y-00041-00022034-00022687": "including the digital footprint, timeless time, the death of distant, poor directionality.", "cixrGwm7G6y-00042-00022687-00022918": "Okay so what is it?", "cixrGwm7G6y-00043-00022918-00023343": "Whistleblowing refers to digitally the disclosure by a person, usually an employee in a government", "cixrGwm7G6y-00044-00023343-00023817": "agency or private enterprise, to the public or to those in authority, of mismanagement,", "cixrGwm7G6y-00045-00023817-00024160": "corruption, illegality, or some other wrongdoing.", "cixrGwm7G6y-00046-00024160-00024691": "And there’s a whistleblower act to protect people who whistle blowing, basically blow", "cixrGwm7G6y-00047-00024691-00025340": "the whistle to say well here in my organization something illegal is going on and they are", "cixrGwm7G6y-00048-00025340-00025863": "protected by this law and there’s a government protection program.", "cixrGwm7G6y-00049-00025863-00026527": "As you see over especially over the last decade or so, the number of cases received by the", "cixrGwm7G6y-00050-00026527-00027151": "US government whistle blower protection program has increased tremendously and there is an", "cixrGwm7G6y-00051-00027151-00027668": "interesting correlation that goes hand in hand with the increase of the usage of digital", "cixrGwm7G6y-00052-00027668-00027863": "tools in the American society.", "cixrGwm7G6y-00053-00027863-00028556": "There have been some very famous cases, and also some platforms strategically designed", "cixrGwm7G6y-00054-00028556-00028656": "for whistleblowing.", "cixrGwm7G6y-00055-00028656-00029319": "For example Wikileaks is a platform where people are not anonymously transcend whistleblower", "cixrGwm7G6y-00056-00029319-00030057": "insight and publish them there and in some cases there were some borderline discussions", "cixrGwm7G6y-00057-00030057-00030627": "between if the whistleblowing or is the giving away actually secret.", "cixrGwm7G6y-00058-00030627-00031416": "Chelsea Manning a former soldier of the United States has been charged 35 years of prism", "cixrGwm7G6y-00059-00031416-00031776": "because of revealing and publishing secrets, several kinds of secrets.", "cixrGwm7G6y-00060-00031776-00032717": "For example about the Iraq war through these kind of whistleblowing platforms and of course,", "cixrGwm7G6y-00061-00032717-00033342": "why was that possible because this information leads this footprint, it can be simply copy", "cixrGwm7G6y-00062-00033342-00033923": "and paste and theres a regular access to these data repositories.", "cixrGwm7G6y-00063-00033923-00034360": "Another very famous case is Edward Snowden, many people also say that it was completely", "cixrGwm7G6y-00064-00034360-00035325": "illegal he revealed state secrets copied between 50-200 thousand documents.", "cixrGwm7G6y-00065-00035325-00035866": "Many of them considered classified state secrets revealed them because they were in digital", "cixrGwm7G6y-00066-00035866-00036387": "form and was quite easy for them to copy and paste economies of scale there was store u", "cixrGwm7G6y-00067-00036387-00036527": "there for a long time.", "cixrGwm7G6y-00068-00036527-00037108": "Maybe some of them even forgotten that they were there, so digitalization made that possible.", "cixrGwm7G6y-00069-00037108-00038055": "Now the intelligence community also confronted this flood of publication of state secrets.", "cixrGwm7G6y-00070-00038055-00038657": "They had this following very interested explanation so the former director of the CIA said “After", "cixrGwm7G6y-00071-00038657-00039192": "9/11 at the terrorist attacks on 9/11, we were accused of not being willing to share", "cixrGwm7G6y-00072-00039192-00039705": "information rapidly and fast enough and we’ve pushed that very far forward.", "cixrGwm7G6y-00073-00039705-00040031": "You guys accused us of that we don’t share information well, well we have a lot of information", "cixrGwm7G6y-00074-00040031-00040886": "so to be shared given many people direct access to these data bases, so let’s share among", "cixrGwm7G6y-00075-00040886-00041190": "the agencies” He also said that “Those of us who've been in this business al long", "cixrGwm7G6y-00076-00041190-00041616": "time knew this day would come.", "cixrGwm7G6y-00077-00041616-00042161": "Knew that because we’d remove all the watertight doors on this ship, once it’s started taking", "cixrGwm7G6y-00078-00042161-00042549": "on water it would really be in trouble.”", "cixrGwm7G6y-00079-00042549-00042988": "So actually knowing about digitalization and knowing that they basically opened the floodgates,", "cixrGwm7G6y-00080-00042988-00043365": "they knew some people would eventually take it out.", "cixrGwm7G6y-00081-00043365-00043852": "It also shows you that, well, digitalization is somewhat of a double edged sword.", "cixrGwm7G6y-00082-00043852-00044735": "It allows you to share and network very fast with many people, and maybe at one point some", "cixrGwm7G6y-00083-00044735-00045097": "people might be interested that there might be legal reasons to why we do not want to", "cixrGwm7G6y-00084-00045097-00045263": "share it.", "cixrGwm7G6y-00085-00045263-00045863": "And also digital solutions and legal framework still have to be invented to assure to take", "cixrGwm7G6y-00086-00045863-00046745": "advantage of the benefits of digitalization and to minimize the drawbacks and dangers.", "cixrGwm7G6y-00087-00046745-00047604": "And finally, Algorithmification is a significant drier of this ongoing human-machine merger.", "cixrGwm7G6y-00088-00047604-00048422": "This cooperation between human intelligence and machine intelligence.", "cixrGwm7G6y-00089-00048422-00048748": "Algorithms nowadays take a lot of decisions.", "cixrGwm7G6y-00090-00048748-00049246": "For example which kind of inside information are we exposed to on the internet, or in social", "cixrGwm7G6y-00091-00049246-00049449": "networks are decisions taken by algorithms.", "cixrGwm7G6y-00092-00049449-00050256": "Algorithms also substitute routines that previously have been regularly carried out by humans.", "cixrGwm7G6y-00093-00050256-00050830": "Be it in the workforce, be it shopping, be it in to robotics in industries.", "cixrGwm7G6y-00094-00050830-00051419": "But the effect of Algorithmification goes beyond economics are the industries or playing", "cixrGwm7G6y-00095-00051419-00051565": "chess.", "cixrGwm7G6y-00096-00051565-00052170": "And can have profound effects even in things like finding the love of your life.", "cixrGwm7G6y-00097-00052170-00052807": "One in three marriages nowadays, in the United States, is produced through online dating", "cixrGwm7G6y-00098-00052807-00053435": "websites is the most common way people get to know each other and eventually marry besides", "cixrGwm7G6y-00099-00053435-00053623": "the introduction of a common friend.", "cixrGwm7G6y-00100-00053623-00054306": "And check out this interesting experience here that Amy had and how she corroborated,", "cixrGwm7G6y-00101-00054306-00054879": "how she started to combine her human intelligence with the machine intelligence give you an", "cixrGwm7G6y-00102-00054879-00055120": "idea about how powerful it can be.", "cixrGwm7G6y-00103-00055120-00055598": "For in the most unexpected result such as, finding the love of your life."}}, {"audio_id": "ciSNaCfjEDu", "text": {"ciSNaCfjEDu-00000-00000046-00000834": "Hello. Welcome to the instructions for Module 5. The topic for Module 5 will be", "ciSNaCfjEDu-00001-00000834-00001664": "the self in control. Here we're going to be looking at choices in actions. Last", "ciSNaCfjEDu-00002-00001664-00002360": "time in, Module 4, we looked really at the definition of the self as well as the", "ciSNaCfjEDu-00003-00002360-00002978": "social nature of the self. Now we'll take this idea a step further to consider the", "ciSNaCfjEDu-00004-00002978-00003875": "idea of freedom, intentions and even the very interesting phenomenon of", "ciSNaCfjEDu-00005-00003875-00004539": "self-defeating behavior. I'd like you to take a moment to reflect back on the", "ciSNaCfjEDu-00006-00004539-00005135": "theories that we've seen in psychology. And the early theories focused on", "ciSNaCfjEDu-00007-00005135-00005846": "internal conflicts that was Freudian theory. Then later we saw the", "ciSNaCfjEDu-00008-00005846-00006285": "behaviorists or learning theory take psychology in a completely", "ciSNaCfjEDu-00009-00006285-00007104": "different direction by looking at behavior as a result of reinforcements", "ciSNaCfjEDu-00010-00007104-00007856": "and punishments. Here in this chapter we'll take that step even further in", "ciSNaCfjEDu-00011-00007856-00008550": "terms of understanding the important role of freedom and believing that we", "ciSNaCfjEDu-00012-00008550-00009222": "have a sense of control over the self. We've had classic social psychology", "ciSNaCfjEDu-00013-00009222-00009804": "research demonstrate that having a sense of control over the self is very", "ciSNaCfjEDu-00014-00009804-00010595": "important for psychological health. Take the example of self-defeating behavior.", "ciSNaCfjEDu-00015-00010595-00011393": "When we see self-defeating behavior in others we often think that it represents", "ciSNaCfjEDu-00016-00011393-00011843": "a sense of failure. In reality self-defeating behavior can be looked at", "ciSNaCfjEDu-00017-00011843-00012354": "as a form of control as somebody is deciding whether or not they want to", "ciSNaCfjEDu-00018-00012354-00012973": "succeed or fail. Okay, let's talk a little bit about the components of the module.", "ciSNaCfjEDu-00019-00012973-00013538": "So for this module you need to read the the chapter associated with the module", "ciSNaCfjEDu-00020-00013538-00014043": "and review the powerpoints. You're also going to be completing the usual", "ciSNaCfjEDu-00021-00014043-00015050": "assignments of module discussion posts, peer responses and module quiz. And then", "ciSNaCfjEDu-00022-00015050-00015813": "this module represents the end of Unit 1 so you'll be taking Unit 1 exam in", "ciSNaCfjEDu-00023-00015813-00016484": "Module 5. It's very important that you think back to all of the different", "ciSNaCfjEDu-00024-00016484-00017773": "topics that we've covered considering that Unit 1 will be covering Chapters 1 through 4 of your textbook. So ,I suggest that you go back and review key concepts", "ciSNaCfjEDu-00025-00017773-00018531": "from each of those 4 chapters as well as reviewing the powerpoints for each of", "ciSNaCfjEDu-00026-00018531-00019404": "the chapters. You only have one opportunity to take the exam and it's", "ciSNaCfjEDu-00027-00019404-00020067": "very important that you do that before the due date as there are no late or", "ciSNaCfjEDu-00028-00020067-00020876": "makeup exams in this course. Okay, congratulations on reaching the end of", "ciSNaCfjEDu-00029-00020876-00021594": "Unit 1 and I will see you back in the module instructions for Module 6 which", "ciSNaCfjEDu-00030-00021594-00022289": "also represents our movement into Unit 2 of the course."}}, {"audio_id": "cjdCxy_vA5A", "text": {"cjdCxy_vA5A-00000-00000006-00000088": "(knock knock knock)", "cjdCxy_vA5A-00001-00000090-00000184": "Hi guys, are you still with us?", "cjdCxy_vA5A-00002-00000187-00000269": "Jiyoung!", "cjdCxy_vA5A-00003-00000271-00000389": "You said “call me if I don’t leave any more comments”", "cjdCxy_vA5A-00004-00000391-00000583": "But, you were only here for 2 days…", "cjdCxy_vA5A-00005-00000585-00000783": "Wow, I think, this one, she gave up…", "cjdCxy_vA5A-00006-00000785-00001173": "“So many people write ‘please like my comment so the notification will bring me back’, but they never return”", "cjdCxy_vA5A-00007-00001300-00001373": "[So let’s call them RIGHT NOW]", "cjdCxy_vA5A-00008-00001375-00001505": "Hi everyone,", "cjdCxy_vA5A-00009-00001507-00001788": "I’m here to talk all about healthy and sustainable dieting.", "cjdCxy_vA5A-00010-00001790-00002000": "I’m Jessie from DanoTV.", "cjdCxy_vA5A-00011-00002002-00002312": "Since 2016, when DanoTV was just starting out,", "cjdCxy_vA5A-00012-00002314-00002448": "we’ve been trying lots of ways", "cjdCxy_vA5A-00013-00002450-00002639": "to give lots of useful information,", "cjdCxy_vA5A-00014-00002641-00002858": "especially for Korean women,", "cjdCxy_vA5A-00015-00002860-00003043": "about healthy and sustainable dieting", "cjdCxy_vA5A-00016-00003045-00003209": "in an enjoyable way.", "cjdCxy_vA5A-00017-00003211-00003382": "So many of you have supported us in doing this", "cjdCxy_vA5A-00018-00003384-00003466": "and have given us", "cjdCxy_vA5A-00019-00003468-00003698": "so much valuable feedback.", "cjdCxy_vA5A-00020-00003700-00004034": "I think that’s why DanoTV has been growing steadily.", "cjdCxy_vA5A-00021-00004036-00004230": "We really appreciate that and have wondered", "cjdCxy_vA5A-00022-00004233-00004461": "how we could express that,", "cjdCxy_vA5A-00023-00004463-00004592": "and so we thought, you know how lots of people", "cjdCxy_vA5A-00024-00004594-00004777": "have been doing the “comments challenges”?", "cjdCxy_vA5A-00025-00004779-00005030": "“I’ll be doing this workout! Please help me to keep going by liking my update comments!”", "cjdCxy_vA5A-00026-00005032-00005281": "So for everyone who’s been posting their workout journeys in the comments,", "cjdCxy_vA5A-00027-00005283-00005499": "today we’ll give a shout out by name", "cjdCxy_vA5A-00028-00005501-00005646": "to all of you, one by one.", "cjdCxy_vA5A-00029-00005648-00005872": "If you’ve left comments on our videos", "cjdCxy_vA5A-00030-00005874-00006030": "and have been doing the workouts with us,", "cjdCxy_vA5A-00031-00006032-00006433": "please watch this video through to the end and check if your name is here!", "cjdCxy_vA5A-00032-00006435-00006669": "[Reading User Comments: I’ll summon you back by name]", "cjdCxy_vA5A-00033-00006671-00006776": "Okay, here we go.", "cjdCxy_vA5A-00034-00006779-00006984": "We’ve searched for any comments", "cjdCxy_vA5A-00035-00006986-00007253": "asking us to hit the like button, and...", "cjdCxy_vA5A-00036-00007256-00007472": "Username: 낡빍볿벩따우 (Nalk-bik-bol-bek-dda-oo)", "cjdCxy_vA5A-00037-00007474-00007698": "“I’m gonna start this now, please like my comment if I don’t post updates!”", "cjdCxy_vA5A-00038-00007700-00007926": "and he/she has done 2 weeks so far!", "cjdCxy_vA5A-00039-00007928-00008011": "Great job!", "cjdCxy_vA5A-00040-00008013-00008162": "Username: 갱(gaeng)mandu... 인화 (Inhwa).", "cjdCxy_vA5A-00041-00008164-00008310": "“인화 (Inhwa)” asked people to like their comments", "cjdCxy_vA5A-00042-00008312-00008478": "but only came back for the first day…", "cjdCxy_vA5A-00043-00008480-00008594": "Username: Happy Olaf", "cjdCxy_vA5A-00044-00008595-00008707": "Oh, user name “happy olaf”", "cjdCxy_vA5A-00045-00008709-00008850": "came back every day for a week.", "cjdCxy_vA5A-00046-00008954-00009039": "Username “야흑 (Yaheuk)” said…", "cjdCxy_vA5A-00047-00009042-00009125": "oh… this is a bit sharp:", "cjdCxy_vA5A-00048-00009127-00009534": "“Most of the people on here are like: they decide to work hard and update their comments.", "cjdCxy_vA5A-00049-00009536-00009912": "It looks alright for the first few days and they ask people to like their comments so they’ll get a notification, and then they never come back.", "cjdCxy_vA5A-00050-00009914-00010147": "Even though I liked their comments, they often don’t come back. But, the people who’ve tried hard, you guys are amazing!”", "cjdCxy_vA5A-00051-00010149-00010248": "Username “김혜윤 (Kim Hye-yoon)”", "cjdCxy_vA5A-00052-00010250-00010513": "“김혜윤 (Kim Hye-yoon)” started the Dano legendary stretches and,", "cjdCxy_vA5A-00053-00010515-00010776": "wow… they did almost 3 weeks in a row!", "cjdCxy_vA5A-00054-00010779-00010946": "You did well!", "cjdCxy_vA5A-00055-00010948-00011110": "Username “배지현 (Bae Ji-hyeon)”", "cjdCxy_vA5A-00056-00011112-00011351": "They wrote the dates for a month in advance", "cjdCxy_vA5A-00057-00011353-00011461": "and did a good job for a while", "cjdCxy_vA5A-00058-00011463-00011671": "but disappeared in the middle of the month,", "cjdCxy_vA5A-00059-00011673-00011874": "and I think, in this case, they set a pretty high goal to start with.", "cjdCxy_vA5A-00060-00011876-00011967": "“노현정 (Noh Hyeon-jung)”", "cjdCxy_vA5A-00061-00011971-00012153": "left comments saying “please give me a notification every day”", "cjdCxy_vA5A-00062-00012155-00012293": "but I can’t see how much work she’s done.", "cjdCxy_vA5A-00063-00012295-00012367": "Are you watching this video Hyeon-jung? (Jessie’s giving her pressure)", "cjdCxy_vA5A-00064-00012371-00013925": "[Listing usernames…]", "cjdCxy_vA5A-00065-00013927-00014119": "“가래침 (Ga-rae-chim)” did a good job at first", "cjdCxy_vA5A-00066-00014122-00014342": "but then they wrote, “I had fried chicken today…”", "cjdCxy_vA5A-00067-00014344-00014432": "and then disappeared.", "cjdCxy_vA5A-00068-00014434-00015587": "[Listing usernames…]", "cjdCxy_vA5A-00069-00015589-00015676": "“조혜진 (Jo Hye-jin)”", "cjdCxy_vA5A-00070-00015678-00015796": "You asked us to call you if don’t come back,", "cjdCxy_vA5A-00071-00015798-00015991": "but you only came back for 2 days...", "cjdCxy_vA5A-00072-00015993-00017279": "[Listing usernames…]", "cjdCxy_vA5A-00073-00017281-00017379": "“찐델리 (Jjin-del-li)” commented on", "cjdCxy_vA5A-00074-00017382-00017814": "the Legendary Stretches, Intense Workout and the 4 Min abs workout.", "cjdCxy_vA5A-00075-00017816-00017976": "She left comments on these three videos,", "cjdCxy_vA5A-00076-00017978-00018146": "asking us to call her back!", "cjdCxy_vA5A-00077-00018148-00018299": "(Jessie’s calling the username three times)", "cjdCxy_vA5A-00078-00018301-00018397": "So I’ll call you three times.", "cjdCxy_vA5A-00079-00018399-00019952": "[Listing usernames…]", "cjdCxy_vA5A-00080-00019954-00020048": "“굶모굶 (Gul-mo-goom)”.", "cjdCxy_vA5A-00081-00020050-00020174": "What’s the meaning of this user name, do you think?", "cjdCxy_vA5A-00082-00020177-00020373": "What’s the point of... skipping meals, just skip meals….(?) (Jessie is trying to guess what the name means)", "cjdCxy_vA5A-00083-00020375-00020606": "and... username \"누가 펭수 소리를 내었는가\"", "cjdCxy_vA5A-00084-00020608-00020826": "Oh, “누가 펭수소리를 내었는가 (who makes the sound of Pengsoo)”", "cjdCxy_vA5A-00085-00020828-00021071": "left comments on 5 videos in total", "cjdCxy_vA5A-00086-00021073-00021251": "and  kept it up for 3 days", "cjdCxy_vA5A-00087-00021253-00021459": "and then… gone…", "cjdCxy_vA5A-00088-00021462-00021653": "*WANTED* Username “who makes the sound of Pengsoo” who wrote “please call me if I don’t update my comments” and then disappeared.", "cjdCxy_vA5A-00089-00021655-00025178": "[Listing usernames…]", "cjdCxy_vA5A-00090-00025180-00025337": "Oh, you said “Please call me if I stop updating”", "cjdCxy_vA5A-00091-00025339-00025436": "so I called your name.", "cjdCxy_vA5A-00092-00025439-00025974": "[Listing usernames…]", "cjdCxy_vA5A-00093-00025976-00026241": "[Wait a moment! It’s time for posture correction! Please correct your posture]", "cjdCxy_vA5A-00094-00026243-00026752": "[Listing usernames…]", "cjdCxy_vA5A-00095-00026754-00026845": "Are you watching this?", "cjdCxy_vA5A-00096-00026847-00027144": "[Listing usernames…]", "cjdCxy_vA5A-00097-00027146-00027221": "and username  \"Seaweed Candy\"", "cjdCxy_vA5A-00098-00027221-00027318": "I want to believe that you’re still doing your exercises!", "cjdCxy_vA5A-00099-00027320-00030068": "[Listing usernames…]", "cjdCxy_vA5A-00100-00030070-00030192": "Okay now,", "cjdCxy_vA5A-00101-00030194-00030413": "I’ve shouted out every single username", "cjdCxy_vA5A-00102-00030415-00030532": "who’s left comments and asked us to call them", "cjdCxy_vA5A-00103-00030534-00030601": "over the past 6 months.", "cjdCxy_vA5A-00104-00030603-00030678": "There’s way more than that", "cjdCxy_vA5A-00105-00030681-00030863": "but I thought we’d have to stay up all night", "cjdCxy_vA5A-00106-00030865-00031012": "to call all of those, so these were just for the last 6 months.", "cjdCxy_vA5A-00107-00031014-00031102": "There are some comments", "cjdCxy_vA5A-00108-00031104-00031286": "that are pretty funny and unique.", "cjdCxy_vA5A-00109-00031288-00031437": "So let’s look through some comments", "cjdCxy_vA5A-00110-00031439-00031622": "and give some tips on how", "cjdCxy_vA5A-00111-00031624-00031906": "to improve your chances of success with the comments challenge.", "cjdCxy_vA5A-00112-00031908-00032329": "Username “쏭님 (Ssong-nim)” said “Please call me if I stop updating my comments! + sad… no one called me”", "cjdCxy_vA5A-00113-00032332-00032512": "But I called you now, so don’t be sad!", "cjdCxy_vA5A-00114-00032514-00032597": "Username “지우 (Ji-oo)” said", "cjdCxy_vA5A-00115-00032599-00032838": "“my legs aren't very toned, please encourage me!”", "cjdCxy_vA5A-00116-00032840-00032953": "and so many people left comments", "cjdCxy_vA5A-00117-00032955-00033201": "to bring her back", "cjdCxy_vA5A-00118-00033203-00033299": "and cheer her on:", "cjdCxy_vA5A-00119-00033301-00033383": "\"where’s she gone?\"", "cjdCxy_vA5A-00120-00033385-00033518": "\"It’s September now, please come back!\"", "cjdCxy_vA5A-00121-00033520-00033761": "And someone else replied \"Yes, I'm coming\"", "cjdCxy_vA5A-00122-00033763-00033999": "There’s lots of conversation going on in the comments!", "cjdCxy_vA5A-00123-00034001-00034081": "Good job everyone!", "cjdCxy_vA5A-00124-00034083-00034231": "Here’s a really good tip:", "cjdCxy_vA5A-00125-00034233-00034387": "Whenever we start a new habit,", "cjdCxy_vA5A-00126-00034389-00034600": "involving other people to encourage us", "cjdCxy_vA5A-00127-00034602-00034735": "is a really effective way of staying motivated.", "cjdCxy_vA5A-00128-00034737-00034897": "For example, making your plans with other people,", "cjdCxy_vA5A-00129-00034899-00035042": "or even making a contract, helps", "cjdCxy_vA5A-00130-00035044-00035222": "us to regularly keep up our activity.", "cjdCxy_vA5A-00131-00035224-00035361": "So I think what’s happening here, calling other people", "cjdCxy_vA5A-00132-00035363-00035519": "to encourage them in exercising,", "cjdCxy_vA5A-00133-00035521-00035663": "is a really good culture!", "cjdCxy_vA5A-00134-00035665-00035766": "Username “피아 (Pi-a)” marked", "cjdCxy_vA5A-00135-00035768-00035917": "the date they did exercise", "cjdCxy_vA5A-00136-00035919-00036214": "with an emoticon whether she did exercise or not", "cjdCxy_vA5A-00137-00036216-00036529": "and also wrote a quick short memo.", "cjdCxy_vA5A-00138-00036532-00036733": "Writing that kind of little memo is a really good habit.", "cjdCxy_vA5A-00139-00036735-00036946": "If you write down a quick memo about", "cjdCxy_vA5A-00140-00036949-00037188": "what’s changed in your body", "cjdCxy_vA5A-00141-00037190-00037370": "and how you feel after exercise,", "cjdCxy_vA5A-00142-00037372-00037529": "then it can actually be a lot of fun.", "cjdCxy_vA5A-00143-00037531-00037674": "When you first start exceeding", "cjdCxy_vA5A-00144-00037676-00037833": "it might be really tiring and you might experience some muscle pain.", "cjdCxy_vA5A-00145-00037835-00037999": "But when you exercise regularly", "cjdCxy_vA5A-00146-00038001-00038178": "you must start feeling a little different every day", "cjdCxy_vA5A-00147-00038180-00038463": "and you can start to see that clearly by recording the changes.", "cjdCxy_vA5A-00148-00038465-00038591": "As “Pi-a” wrote here,", "cjdCxy_vA5A-00149-00038593-00038792": "they sometimes didn’t do exercise if he or she was feeling sick,", "cjdCxy_vA5A-00150-00038794-00039004": "and one day they wrote “I thought my legs will snap”", "cjdCxy_vA5A-00151-00039006-00039319": "then, “I was sweating so much but it wasn’t hard anymore”,", "cjdCxy_vA5A-00152-00039322-00039622": "“I’ve been doing this every day, and I can see the difference in the mirror!”", "cjdCxy_vA5A-00153-00039624-00039842": "It took only 10 days for them to feel like that.", "cjdCxy_vA5A-00154-00039849-00040085": "After that, they sometimes skipped their exercise", "cjdCxy_vA5A-00155-00040087-00040219": "and one day wrote “I just didn’t want to do any exercise today”.", "cjdCxy_vA5A-00156-00040221-00040865": "But on their last day, they wrote that “One month is done! I could barely do 10 sit-ups, but now I can do 30!”", "cjdCxy_vA5A-00157-00040869-00041001": "“Pi-a”, well done! Great job.", "cjdCxy_vA5A-00158-00041004-00041108": "Username “혜림최 (Hye-rim Choi)” said", "cjdCxy_vA5A-00159-00041110-00041485": "“I desperately want to lose weight. I’ll do this every day!” but…", "cjdCxy_vA5A-00160-00041487-00041692": "they’re gone after 3 days.", "cjdCxy_vA5A-00161-00041694-00041941": "My recommendation for her, or people like her, is to not make a one-month goal.", "cjdCxy_vA5A-00162-00041943-00042021": "It’s better to start with a small goal!", "cjdCxy_vA5A-00163-00042023-00042116": "She did 3 days here, right?", "cjdCxy_vA5A-00164-00042119-00042280": "So she could make a 3-day goal first and finish it,", "cjdCxy_vA5A-00165-00042282-00042511": "then she could try 5-day goal", "cjdCxy_vA5A-00166-00042513-00042793": "and then, little by little, she can work up to one-month goal later on.", "cjdCxy_vA5A-00167-00042795-00042915": "She would’ve been succeeded", "cjdCxy_vA5A-00168-00042917-00043168": "if her first challenge was just a 3-day plan, right?", "cjdCxy_vA5A-00169-00043170-00043483": "I hope you don't feel embarrassed about your effort", "cjdCxy_vA5A-00170-00043485-00043628": "and come back again,", "cjdCxy_vA5A-00171-00043630-00043837": "and this time try and start a 5-day challenge!", "cjdCxy_vA5A-00172-00043839-00043919": "The next user was", "cjdCxy_vA5A-00173-00043921-00044081": "a really, super popular commenter", "cjdCxy_vA5A-00174-00044083-00044210": "in one these these comment challenges.", "cjdCxy_vA5A-00175-00044212-00044318": "Username “이름어써 (Ireum uh-sseo) said", "cjdCxy_vA5A-00176-00044320-00044762": "“Can you please call me? Please! I never stick to anything. Please tell me off!”", "cjdCxy_vA5A-00177-00044764-00045066": "So, about 800 people liked that comment", "cjdCxy_vA5A-00178-00045068-00045248": "and there are 69 replies.", "cjdCxy_vA5A-00179-00045250-00045582": "Lots of people have tried to encourage him or her back saying \"Come back\", \"It's time to exercise!\"", "cjdCxy_vA5A-00180-00045585-00045697": "but… they haven’t come again.", "cjdCxy_vA5A-00181-00045699-00045786": "Including me,", "cjdCxy_vA5A-00182-00045788-00046001": "70 people are waiting for you to come back now,", "cjdCxy_vA5A-00183-00046003-00046267": "so… “Ireum uh-sseo”, please come back to us", "cjdCxy_vA5A-00184-00046269-00046484": "and finish off this challenge!", "cjdCxy_vA5A-00185-00046486-00046575": "Username “이지영 (Lee Ji-young)”", "cjdCxy_vA5A-00186-00046577-00046642": "has got...", "cjdCxy_vA5A-00187-00046644-00046885": "485 likes and 44 comments.", "cjdCxy_vA5A-00188-00046887-00047027": "We’re all looking for you,", "cjdCxy_vA5A-00189-00047029-00047111": "so please come back!", "cjdCxy_vA5A-00190-00047113-00047321": "It’s like that TV show ‘Love on the Air”", "cjdCxy_vA5A-00191-00047323-00047439": "“Jiyoung~”", "cjdCxy_vA5A-00192-00047518-00047665": "(MC: “You have to call a bit louder!”)", "cjdCxy_vA5A-00193-00047667-00047826": "You know what I'm doing, right?", "cjdCxy_vA5A-00194-00047828-00047923": "(Is this show too old for you guys..? ) (Please tell me you know it…)", "cjdCxy_vA5A-00195-00047925-00048070": "Next, username “꿍까 (Goong-ga)”", "cjdCxy_vA5A-00196-00048072-00048328": "kept it up for a while and then wrote", "cjdCxy_vA5A-00197-00048330-00048631": "“I fell asleep” on the 12th…", "cjdCxy_vA5A-00198-00048698-00048839": "Are you still asleep", "cjdCxy_vA5A-00199-00048841-00048940": "Goong-ga…?", "cjdCxy_vA5A-00200-00048942-00049074": "Please wake up!", "cjdCxy_vA5A-00201-00049076-00049192": "And the next one is", "cjdCxy_vA5A-00202-00049194-00049414": "username “그만 불러주세요” (“please stop calling me”)", "cjdCxy_vA5A-00203-00049416-00049532": "so, okay, I won’t call you anymore.", "cjdCxy_vA5A-00204-00049534-00049683": "[Reading Comments: I'll summon you back by name]", "cjdCxy_vA5A-00205-00049686-00049940": "Okay, so I wish I could have read all the comments", "cjdCxy_vA5A-00206-00049942-00050110": "that our 700k subscribers have posted on our videos", "cjdCxy_vA5A-00207-00050112-00050320": "over the last 4 years", "cjdCxy_vA5A-00208-00050322-00050445": "but, even though I couldn’t do that,", "cjdCxy_vA5A-00209-00050447-00050747": "I’ve tried to shout out to all the users who’ve asked for us to respond", "cjdCxy_vA5A-00210-00050749-00050897": "to their comments within past 6 months.", "cjdCxy_vA5A-00211-00050899-00051071": "So many people have now watched", "cjdCxy_vA5A-00212-00051073-00051351": "our DanoTV exercise videos.", "cjdCxy_vA5A-00213-00051353-00051514": "And they weren’t just watching it,", "cjdCxy_vA5A-00214-00051516-00051660": "they were doing the exercises along with us,", "cjdCxy_vA5A-00215-00051662-00051884": "decisively putting down their mats.", "cjdCxy_vA5A-00216-00051886-00052096": "We’re really so touched by all of that, and it’s so rewarding for us.", "cjdCxy_vA5A-00217-00052098-00052186": "And on the other hand,", "cjdCxy_vA5A-00218-00052188-00052453": "whenever we see that people stop posting their progress", "cjdCxy_vA5A-00219-00052455-00052682": "and don’t come back even though we liked their comments in order to send them a notification,", "cjdCxy_vA5A-00220-00052684-00052864": "in that case, we really, desperately", "cjdCxy_vA5A-00221-00052866-00053157": "want to give them some motivation to restart their exercise.", "cjdCxy_vA5A-00222-00053159-00053546": "So to sum up what we’ve been talking about today,", "cjdCxy_vA5A-00223-00053548-00053861": "about how to best use the comments for your challenges:", "cjdCxy_vA5A-00224-00053863-00054014": "when you post comments to keep track of your journey,", "cjdCxy_vA5A-00225-00054016-00054084": "first,", "cjdCxy_vA5A-00226-00054086-00054531": "start with a small goal, like a 3-day goal or 5-day goal.", "cjdCxy_vA5A-00227-00054534-00054685": "I reckon that among all the people who’ve decided to do a comments challenge,", "cjdCxy_vA5A-00228-00054687-00054904": "there’s almost no one who really can’t complete a three day challenge.", "cjdCxy_vA5A-00229-00054907-00054998": "And what that means is,", "cjdCxy_vA5A-00230-00055000-00055140": "if you start with a 3-day goal", "cjdCxy_vA5A-00231-00055142-00055305": "then you’re highly likely to succeed!", "cjdCxy_vA5A-00232-00055307-00055565": "With that little feeling of achievement,", "cjdCxy_vA5A-00233-00055567-00055758": "I hope that you’ll be motivated to", "cjdCxy_vA5A-00234-00055760-00055893": "do a 5-day, 7-day, 2-week", "cjdCxy_vA5A-00235-00055895-00056059": "and, finally, a one-month challenge.", "cjdCxy_vA5A-00236-00056061-00056166": "And the second thing is", "cjdCxy_vA5A-00237-00056169-00056278": "the power of checking off your progress.", "cjdCxy_vA5A-00238-00056280-00056462": "I recommend not just asking people to send you like,", "cjdCxy_vA5A-00239-00056464-00056670": "but also use some of your favourite emojis", "cjdCxy_vA5A-00240-00056672-00056900": "to check off whether or not you did that day.", "cjdCxy_vA5A-00241-00056902-00057020": "You don’t have to use comments section for that either,", "cjdCxy_vA5A-00242-00057022-00057171": "you can use your calendar, or scheduler", "cjdCxy_vA5A-00243-00057173-00057400": "or anything that you can check visually.", "cjdCxy_vA5A-00244-00057402-00057606": "But what’s good thing about using the comment son YouTube", "cjdCxy_vA5A-00245-00057608-00057743": "is that it’s a shared space.", "cjdCxy_vA5A-00246-00057745-00058026": "So, rather than just making your own plan in private,", "cjdCxy_vA5A-00247-00058028-00058208": "you’ll feel like it’s a plan that you’ve shared with others,", "cjdCxy_vA5A-00248-00058210-00058339": "and that can boost your motivation.", "cjdCxy_vA5A-00249-00058341-00058469": "The third one is,", "cjdCxy_vA5A-00250-00058471-00058783": "the benefit of helping and cheering each other on.", "cjdCxy_vA5A-00251-00058785-00059025": "If you’re someone who hasn’t done any exercise before,", "cjdCxy_vA5A-00252-00059027-00059101": "then for you,", "cjdCxy_vA5A-00253-00059103-00059221": "making a decision to exercise every day", "cjdCxy_vA5A-00254-00059223-00059455": "really isn’t an easy thing to do.", "cjdCxy_vA5A-00255-00059457-00059710": "But if you write a reply to people in that situation,", "cjdCxy_vA5A-00256-00059713-00059969": "and they leave a comment on your posts,", "cjdCxy_vA5A-00257-00059971-00060063": "or send you a like,", "cjdCxy_vA5A-00258-00060065-00060190": "then you’re exchanging notifications with each other.", "cjdCxy_vA5A-00259-00060192-00060508": "Those notification can prompt someone like ‘Okay, I’ll exercise today!”", "cjdCxy_vA5A-00260-00060510-00060789": "and actually motivate them do it.", "cjdCxy_vA5A-00261-00060791-00061027": "Those notifications can turn out to be a strong motivation.", "cjdCxy_vA5A-00262-00061029-00061184": "You guys are already doing really well", "cjdCxy_vA5A-00263-00061186-00061350": "but I hope that all our DanoTV subscribers", "cjdCxy_vA5A-00264-00061352-00061544": "can make our comments section a really special social space", "cjdCxy_vA5A-00265-00061546-00061751": "by encouraging and cheering each other on.", "cjdCxy_vA5A-00266-00061753-00061833": "The fourth tip is…", "cjdCxy_vA5A-00267-00061835-00062107": "there will be some days where you really can’t exercise.", "cjdCxy_vA5A-00268-00062109-00062275": "You might be sick or just not in a mood to exercise,", "cjdCxy_vA5A-00269-00062277-00062421": "for whatever reason. In that case", "cjdCxy_vA5A-00270-00062423-00062637": "I hope you won’t think, ‘I’ve failed, I give up’", "cjdCxy_vA5A-00271-00062639-00062859": "but instead try it again.", "cjdCxy_vA5A-00272-00062861-00063017": "When I look through everyone’s comments,", "cjdCxy_vA5A-00273-00063020-00063115": "the people who’ve achieved their goals and", "cjdCxy_vA5A-00274-00063117-00063342": "successfully changed their bodies and habits aren’t the ones", "cjdCxy_vA5A-00275-00063344-00063530": "who never skipped a day of exercise.", "cjdCxy_vA5A-00276-00063532-00063760": "Sometimes they did skip their exercise but", "cjdCxy_vA5A-00277-00063762-00063945": "they kept coming back and finished it.", "cjdCxy_vA5A-00278-00063947-00064005": "If you skipped an exercise", "cjdCxy_vA5A-00279-00064007-00064134": "then write that down too.", "cjdCxy_vA5A-00280-00064136-00064317": "You can write down not just your successes, but also your failures.", "cjdCxy_vA5A-00281-00064319-00064561": "I hope you’ll remember the power of recording your progress,", "cjdCxy_vA5A-00282-00064563-00064828": "regardless of success or failure.", "cjdCxy_vA5A-00283-00064830-00064906": "And, finally,", "cjdCxy_vA5A-00284-00064908-00065205": "keeping a record of your thoughts and feelings, like changes in your body", "cjdCxy_vA5A-00285-00065208-00065296": "and in your attitude,", "cjdCxy_vA5A-00286-00065298-00065910": "is just as important as recording whether or not you’ve exercised.", "cjdCxy_vA5A-00287-00065912-00066108": "It helps to motivate not only yourself", "cjdCxy_vA5A-00288-00066110-00066398": "but also any other Danovelies who might read your comments.", "cjdCxy_vA5A-00289-00066400-00066550": "They might think", "cjdCxy_vA5A-00290-00066552-00066649": "“should I try too?”", "cjdCxy_vA5A-00291-00066652-00066858": "My biggest hope for the DanoTV YouTube channel is", "cjdCxy_vA5A-00292-00066860-00067147": "that people can share their good an positive experiences and", "cjdCxy_vA5A-00293-00067149-00067359": "can encourage each other", "cjdCxy_vA5A-00294-00067361-00067527": "to establish new habits.", "cjdCxy_vA5A-00295-00067529-00067831": "[Dano TV Subscribe and Like!]", "cjdCxy_vA5A-00296-00067833-00068058": "I hope that more and more people", "cjdCxy_vA5A-00297-00068061-00068209": "will do the comments challenges.", "cjdCxy_vA5A-00298-00068211-00068312": "And we here at DanoTV", "cjdCxy_vA5A-00299-00068314-00068506": "will also give you a like on your comments.", "cjdCxy_vA5A-00300-00068508-00068677": "So, especially for those who I have a shout out to today,", "cjdCxy_vA5A-00301-00068679-00068909": "please come back to us and continue your diet/exercise journey with us!", "cjdCxy_vA5A-00302-00068911-00069116": "And for those who’ve never tried this challenge,", "cjdCxy_vA5A-00303-00069118-00069238": "I recommend giving a try from today!", "cjdCxy_vA5A-00304-00069240-00069422": "I’ll see you in the next video!", "cjdCxy_vA5A-00305-00069424-00069651": "Bye for now!"}}, {"audio_id": "cjF-wack7fk", "text": {"cjF-wack7fk-00000-00002258-00002352": "[MUSIC].  I'm Dan Gilbert.", "cjF-wack7fk-00001-00002352-00002650": "I'm a social psychologist and professor  here at Harvard University.", "cjF-wack7fk-00002-00002762-00003164": "For centuries, happiness has been a  subject for poets and philosophers, but", "cjF-wack7fk-00003-00003164-00003629": "in the last few decades, psychologists,  neuroscientists, even economists, have", "cjF-wack7fk-00004-00003629-00004044": "begun to study happiness using the same  scientific methods they use to study", "cjF-wack7fk-00005-00004044-00004197": "every other aspect of human behavior.  [MUSIC]", "cjF-wack7fk-00006-00004800-00005098": ">> Of course, scientists have only  recently gotten into the happiness", "cjF-wack7fk-00007-00005098-00005422": "business, but that business has been  booming for a long time.", "cjF-wack7fk-00008-00005551-00005887": ">> You have to train your mind to  recall the simple successes.", "cjF-wack7fk-00009-00005887-00006046": "[INAUDIBLE]   >> Turn on the television, surf the", "cjF-wack7fk-00010-00006046-00006412": "web, visit a bookstore, and you'll see  that there's no shortage of people", "cjF-wack7fk-00011-00006412-00006743": "offering advice about happiness.   >> [MUSIC] Success university.", "cjF-wack7fk-00012-00006743-00007145": ">> Going to be fun, y'all.   >> All my needs, desires, and goals.", "cjF-wack7fk-00013-00007145-00007487": ">> They're all part of a large and  growing business known as the self-help", "cjF-wack7fk-00014-00007487-00007772": "industry.   >> It's a liberation from your self", "cjF-wack7fk-00015-00007772-00007988": "image.   >> This industry may or may not have", "cjF-wack7fk-00016-00007988-00008385": "made anyone happy, but it's definitely  made some people very rich.", "cjF-wack7fk-00017-00008385-00009100": "[MUSIC] [INAUDIBLE]   >> Last year, Americans spent about $10", "cjF-wack7fk-00018-00009120-00009618": "billion on self help.   >> You're in a preferred section.", "cjF-wack7fk-00019-00009618-00010130": ">> Much of that money was brought in by  conferences like this one, run by Hay", "cjF-wack7fk-00020-00010130-00011114": "House, a leading self-help publisher.  Hay House sells books and DVDs on", "cjF-wack7fk-00021-00011114-00011537": "everything from diet and personal fitness  to fairy magic and angel therapy.", "cjF-wack7fk-00022-00011537-00011807": ">> Wow, there's a lot of money to be  spent here.", "cjF-wack7fk-00023-00011807-00011907": ">> Yes, there is.   >> Yes.", "cjF-wack7fk-00024-00011907-00012153": ">> How much money are you going to  spend here?", "cjF-wack7fk-00025-00012153-00012386": ">> Not that much.   >> Well, we didn't even make it around", "cjF-wack7fk-00026-00012386-00012679": "the table, but it looks like we're  going to be spending a lot.", "cjF-wack7fk-00027-00012679-00012958": "Stuff looks great.   >> The desire for happiness drives", "cjF-wack7fk-00028-00012958-00013322": "different people toward different things.  Some have come here hoping to lose", "cjF-wack7fk-00029-00013322-00013579": "weight, some are hoping to find a new partner, a", "cjF-wack7fk-00030-00013579-00013869": "new career, or a whole new view of the  universe.", "cjF-wack7fk-00031-00013869-00014178": ">> Unbelievably, amazingly mind over  body connections.", "cjF-wack7fk-00032-00014178-00014354": ">> Yeah.   >> Getting a better job, love,", "cjF-wack7fk-00033-00014354-00014722": "relationships, all that kind of stuff.   >> Yeah, all the- all the good things", "cjF-wack7fk-00034-00014722-00014943": "in life.   >> But some people have come here with", "cjF-wack7fk-00035-00014943-00015262": "very serious problems, and they may not be in the right place.", "cjF-wack7fk-00036-00015402-00015847": "Many have been drawn by Louise Hay, the  founder of Hay House.", "cjF-wack7fk-00037-00015847-00016110": "She claims to have cured herself of  cancer", "cjF-wack7fk-00038-00016110-00016459": "through positive thinking, and other  self-help techniques, and she tells", "cjF-wack7fk-00039-00016459-00016901": "others that they can do it too.  Although her claims have never been", "cjF-wack7fk-00040-00016901-00017359": "medically verified, she's been a guest on  Oprah, and her memoir, \"Heal Your Life,\"", "cjF-wack7fk-00041-00017359-00017890": "has sold over 35 million copies,  making her one of the best-selling", "cjF-wack7fk-00042-00017890-00018018": "authors of all time.  [MUSIC]", "cjF-wack7fk-00043-00018018-00018375": ">> Please join me in welcoming Louise  Hay.", "cjF-wack7fk-00044-00018375-00019991": ">> I choose the thoughts that make me  feel good.", "cjF-wack7fk-00045-00020099-00020485": ">> Life loves you, I love you, do you love you?", "cjF-wack7fk-00046-00020485-00020750": ">> Yes.   >> That's the important thing.", "cjF-wack7fk-00047-00020750-00021016": ">> We love you.   >> Thank you, thank you.", "cjF-wack7fk-00048-00021016-00021242": "I accept, I do.  You're damn right.", "cjF-wack7fk-00049-00021242-00021723": "[LAUGH].   >> But Hay also believes that thoughts", "cjF-wack7fk-00050-00021723-00022155": "are the cause of all misfortunes. >> Because remember, somebody who has", "cjF-wack7fk-00051-00022155-00022657": "depression is choosing thoughts that  make them feel rotten.", "cjF-wack7fk-00052-00022657-00023060": ">> That by thinking the wrong way we  can give ourselves cancer or AIDS, or", "cjF-wack7fk-00053-00023060-00023511": "depression, cause cars to hit us, or make  ourselves the target of a terrorist", "cjF-wack7fk-00054-00023511-00023841": "attack.   >> When I became 80 I decided that it", "cjF-wack7fk-00055-00023841-00024233": "was going to be the best decade of my  entire life, and it is!", "cjF-wack7fk-00056-00024233-00024661": "[NOISE] I'm 82!  >> As I go through your book I see all", "cjF-wack7fk-00057-00024661-00025097": "sorts of maladies  >> Mm-hm.   >> and various kinds of thoughts   >> Mm-hm.", "cjF-wack7fk-00058-00025097-00025261": ">> that you say   >> Mm-hmm.   >> can cause them.", "cjF-wack7fk-00059-00025261-00025802": "Alzheimer's is an inability to face life,  leprosy, inability to handle life at all.", "cjF-wack7fk-00060-00025802-00026114": ">> Oh, you're picking the fun ones.   >> People who have Alzheimer's are", "cjF-wack7fk-00061-00026114-00026481": "really removing themselves from life  completely.", "cjF-wack7fk-00062-00026481-00026681": ">> How do you know?  How do you know what you're saying is", "cjF-wack7fk-00063-00026681-00026693": "right?   >> Mm-hm.", "cjF-wack7fk-00064-00026693-00026854": "Oh, my inner ding.   >> Your inner ding?", "cjF-wack7fk-00065-00026854-00027029": ">> My inner ding.   >> Ding?", "cjF-wack7fk-00066-00027029-00027520": ">> It speaks to me, yes.  It feels right or it doesn't feel right.", "cjF-wack7fk-00067-00027520-00027870": "Happiness is choosing thoughts that make you feel good.", "cjF-wack7fk-00068-00027870-00028339": "It's really very simple.   >> I hear you saying that even if there", "cjF-wack7fk-00069-00028339-00028892": "were no proof for what you believe, or even if there was scientific evidence", "cjF-wack7fk-00070-00028892-00028975": "against it,  it wouldn't change.", "cjF-wack7fk-00071-00028975-00029182": ">> Oh, I don't believe in scientific  evidence.", "cjF-wack7fk-00072-00029182-00029577": "I really don't.  And science is fairly new.", "cjF-wack7fk-00073-00029577-00029977": "Hasn't been around that long. We think it's  such a big deal, but it's, you know, it's", "cjF-wack7fk-00074-00029977-00030310": "just a way of looking at life.   >> But you're telling it to millions of", "cjF-wack7fk-00075-00030310-00030493": "people, and you're telling them it's  right for them too.", "cjF-wack7fk-00076-00030493-00031327": ">> I tell them what's right for me.  My inner ding, that's all I can say.", "cjF-wack7fk-00077-00031327-00031639": "[MUSIC]   >> You know what? Science is fairly", "cjF-wack7fk-00078-00031639-00031879": "new, but when we want to know what causes", "cjF-wack7fk-00079-00031879-00032201": "stars to explode, or butterflies to  migrate,", "cjF-wack7fk-00080-00032201-00032626": "we rely on scientific evidence rather  than our inner ding.", "cjF-wack7fk-00081-00032626-00033051": "So why not do the same thing to find out  what causes human happiness?", "cjF-wack7fk-00082-00033051-00033550": ">> For thousands of years philosophers  were asking about happiness and talking", "cjF-wack7fk-00083-00033550-00033988": "about happiness but without any data, and  only probably in the last thirty or forty", "cjF-wack7fk-00084-00033988-00034428": "years have we actually collected  scientific data, rigorous data, measured", "cjF-wack7fk-00085-00034428-00034947": "happiness, and started to begin to see  what is it that leads to happiness.", "cjF-wack7fk-00086-00034947-00035290": "Psychologist, Ed Diener, is a pioneer in  the study of happiness.", "cjF-wack7fk-00087-00035290-00035815": "Since 1980, he and his collaborators have  crossed the globe to measure it,", "cjF-wack7fk-00088-00035815-00036346": "surveying diverse communities from the  Masai tribe in Africa, to the Inuit from", "cjF-wack7fk-00089-00036346-00036795": "northern Canada, to the Amish of rural Pennsylvania, and", "cjF-wack7fk-00090-00036795-00037265": "many, many others.  And the methods Diener uses are as diverse", "cjF-wack7fk-00091-00037265-00037661": "as his subjects.   >> In happiness research, we ask people", "cjF-wack7fk-00092-00037661-00038208": "how happy they are in a one to ten scale.  We also look at brain waves.", "cjF-wack7fk-00093-00038208-00038683": ">> You can look at hormones like  cortisol that reflect stress, for example.", "cjF-wack7fk-00094-00038683-00039152": "You can also ask family and friends how  happy that person is because family and", "cjF-wack7fk-00095-00039152-00039640": "friends see how happy they say they are  and how happy they act in everyday life.", "cjF-wack7fk-00096-00039640-00039996": "[MUSIC]   >> Diener has gathered data on nearly a", "cjF-wack7fk-00097-00039996-00040315": "quarter million people, and has found that the happy ones", "cjF-wack7fk-00098-00040315-00040762": "have better health, better relationships,  better sex lives, better careers, and", "cjF-wack7fk-00099-00040762-00041234": "better just about everything else.   >> We think that's an evolutionary", "cjF-wack7fk-00100-00041234-00041703": "thing, and the people who are happy  probably out-achieve the other people and", "cjF-wack7fk-00101-00041703-00041942": "out-reproduce them and there's more of us  around now.", "cjF-wack7fk-00102-00041983-00042373": ">> Diener's findings have been  confirmed by psychologists,", "cjF-wack7fk-00103-00042373-00042642": "neuroscientists, and economists around  the world.", "cjF-wack7fk-00104-00042746-00043096": "We now know a great deal about what  actually makes people happy,", "cjF-wack7fk-00105-00043096-00043639": "and it isn't always what we think.   >> What does happiness mean to you?", "cjF-wack7fk-00106-00043639-00044018": ">> I'm a firm believer in money  is happiness. Ok? I have to be", "cjF-wack7fk-00107-00044018-00044237": "honest.   >> My children, because I love my", "cjF-wack7fk-00108-00044237-00044470": "children.   >> I like my summer camp the best.", "cjF-wack7fk-00109-00044470-00044667": ">> Is that the best?  That makes you happy?", "cjF-wack7fk-00110-00044667-00044887": ">> What do you do to make yourself  happier?", "cjF-wack7fk-00111-00044887-00045305": ">> Well I don't mean to be  recalcitrant, but I don't do anything in", "cjF-wack7fk-00112-00045305-00045637": "order to be happy.   >> Yeah, rolling down your window, and", "cjF-wack7fk-00113-00045637-00045921": "turn the music on, letting the breeze  come in.", "cjF-wack7fk-00114-00045921-00046285": ">> What would you say is your greatest  source of happiness?", "cjF-wack7fk-00115-00046285-00046672": ">> Well, I get a great deal of happiness  from beautiful jewelry.", "cjF-wack7fk-00116-00046672-00046752": ">> Jewelry?   >> Yes.", "cjF-wack7fk-00117-00046752-00046865": "[LAUGH]   >> There are a lot of different", "cjF-wack7fk-00118-00046865-00047284": "opinions about what causes happiness, but research suggests that not", "cjF-wack7fk-00119-00047284-00047606": "all of them are exactly on target.   >> And do you think marriage is a", "cjF-wack7fk-00120-00047606-00047867": "source of happiness?   >> Most of the time.", "cjF-wack7fk-00121-00047867-00048243": "[LAUGH] Depends on how- what your  marriage is like.", "cjF-wack7fk-00122-00048243-00048553": ">> What do you think about marriage?  Do you think it's a source of happiness", "cjF-wack7fk-00123-00048553-00048631": "for most people?   >> No.", "cjF-wack7fk-00124-00048631-00048944": ">> What about marriage?  Do you think married people are happier", "cjF-wack7fk-00125-00048944-00049051": "than unmarried people?   >> No.", "cjF-wack7fk-00126-00049051-00049469": "I don't think they're less happy,  I think it just depends.", "cjF-wack7fk-00127-00049469-00049817": ">> Not everyone lives happily ever  after, of course,", "cjF-wack7fk-00128-00049817-00050365": "but studies do show that, on average,  married people are wealthier, healthier,", "cjF-wack7fk-00129-00050365-00050808": "and yes, happier than others.  [MUSIC] Do you think children make people", "cjF-wack7fk-00130-00050808-00050921": "happy?   >> I think so.", "cjF-wack7fk-00131-00050921-00051209": ">> I mean, I think they will be a part  of my happiness.", "cjF-wack7fk-00132-00051209-00051378": ">> Yes or no, do children make you  happy?", "cjF-wack7fk-00133-00051378-00051769": ">> [LAUGH] Yes, mine do.   >> So what about those bundles of joy?", "cjF-wack7fk-00134-00051769-00052216": "Well, studies show that parents are no  happier than non-parents, and are often", "cjF-wack7fk-00135-00052216-00052479": "less happy.  [MUSIC] Can money buy happiness?", "cjF-wack7fk-00136-00052479-00052808": ">> No, no it doesn't.   >> Do you think money can buy", "cjF-wack7fk-00137-00052808-00052970": "happiness, can it bring happiness?   >> No.", "cjF-wack7fk-00138-00052970-00053231": ">> Does money buy happiness?  >> Not at all.", "cjF-wack7fk-00139-00053231-00053588": ">> What about money?  Do you think money makes people happy?", "cjF-wack7fk-00140-00053588-00053788": ">> Absolutely.   >> Yeah  >> Mhmm.", "cjF-wack7fk-00141-00053788-00054219": ">> The more the better?   >> For me especially, the more the", "cjF-wack7fk-00142-00054219-00054382": "better.   >> Guess what?", "cjF-wack7fk-00143-00054382-00054754": "Money does cause happiness.  On average, the more money people have,", "cjF-wack7fk-00144-00054754-00055226": "the happier they tend to be.  So money? Yes. Marriage? Probably.", "cjF-wack7fk-00145-00055226-00055678": "Children? Not so much.  What science is teaching us about these", "cjF-wack7fk-00146-00055678-00056180": "and many other things is that they are  related to happiness, but not necessarily", "cjF-wack7fk-00147-00056180-00056624": "in the way you might think.   >> In a recent experiment, researchers", "cjF-wack7fk-00148-00056624-00056873": "went to a health club and asked a simple  question.", "cjF-wack7fk-00149-00056873-00057188": ">> You're going to live in the woods  for two days and two nights.", "cjF-wack7fk-00150-00057188-00057751": "You can have food or water but not both,  which would you rather have, food or", "cjF-wack7fk-00151-00057751-00057969": "water?   >> Food.", "cjF-wack7fk-00152-00057969-00058501": ">> I'd say food.   >> Okay, I'll circle that.", "cjF-wack7fk-00153-00058501-00058875": ">> Some of the people were asked this  question before they worked out. Some", "cjF-wack7fk-00154-00058875-00059347": "were asked after they worked out. And when they were asked made a huge", "cjF-wack7fk-00155-00059347-00059835": "difference in how they answered.  In fact, people were 50 percent more likely to", "cjF-wack7fk-00156-00059835-00060275": "say water if they'd just finished working  out than if they were about to start.", "cjF-wack7fk-00157-00060275-00060593": ">> Water, definitely water.", "cjF-wack7fk-00158-00060593-00060925": ">> [MUSIC] [INAUDIBLE] Why?  People were thirsty after exercising,", "cjF-wack7fk-00159-00060925-00061309": "and because they were thirsty now, they  imagined being thirsty in the future.", "cjF-wack7fk-00160-00061309-00061739": "This is something our brains do all the  time.", "cjF-wack7fk-00161-00061739-00062136": "When we think about how we'll feel in the  future, our thoughts are shaped by how we", "cjF-wack7fk-00162-00062136-00062521": "feel in the present.  [MUSIC] It's as if our brains can't", "cjF-wack7fk-00163-00062521-00062871": "believe that we might feel differently  later than we do now.", "cjF-wack7fk-00164-00062871-00063457": "[NOISE] That's not the only thing our  brains can't quite believe.", "cjF-wack7fk-00165-00063457-00063907": "We all know that feelings inevitably  change over time, that new love fades,", "cjF-wack7fk-00166-00063907-00064384": "that fresh wounds heal, and yet when we  imagine our future joys and our future", "cjF-wack7fk-00167-00064384-00064838": "sorrows, we tend not to think about how  time will change them.", "cjF-wack7fk-00168-00064838-00065184": ">> We sure do have the compelling  intuition that somehow improving our", "cjF-wack7fk-00169-00065184-00065633": "life circumstances, our situations,  whether it has to do with relationships,", "cjF-wack7fk-00170-00065633-00066004": "or jobs, or health, that that's going to  make us happier,", "cjF-wack7fk-00171-00066004-00066368": "and the truth is that it does make us  happier, but it doesn't make us happier", "cjF-wack7fk-00172-00066368-00066666": "for as long or as intensely as we think it would.", "cjF-wack7fk-00173-00066666-00067132": ">> Psychologist Sonia Lubamaerski  suggests that we're sadly mistaken when", "cjF-wack7fk-00174-00067132-00067564": "we expect that the things that make us  happy for a day will make us happy for a", "cjF-wack7fk-00175-00067564-00067933": "lifetime.   >> It's a phenomenon called Hedonic", "cjF-wack7fk-00176-00067933-00068470": "Adaptation, which means that human beings  basically are- are just incredibly good", "cjF-wack7fk-00177-00068470-00068952": "at getting used to, getting accustomed to,  adapting positive changes, especially in", "cjF-wack7fk-00178-00068952-00069308": "their lives,  like the new car or the new house,", "cjF-wack7fk-00179-00069308-00069843": "and so that's one of the reasons that we  keep sort of buying more stuff, is that we,", "cjF-wack7fk-00180-00069843-00070263": "you know, we get a handbag that gives us  a boost, it wears off, and then we get a", "cjF-wack7fk-00181-00070263-00070673": "new handbag.   >> Adaptation affects our experience of", "cjF-wack7fk-00182-00070673-00071162": "both good things and bad things in ways  that we find difficult to anticipate.", "cjF-wack7fk-00183-00071162-00071527": "This is something my colleagues and I  have been studying in the lab.", "cjF-wack7fk-00184-00071527-00071810": ">>And we'd be very happy to give you one as  a gift for participating in the", "cjF-wack7fk-00185-00071810-00072026": "experiment.  Which one would you like to have?", "cjF-wack7fk-00186-00072174-00072576": ">> In one experiment, we brought people  into a room filled with art posters and", "cjF-wack7fk-00187-00072576-00073008": "offered to give them one.  We told half of the participants that", "cjF-wack7fk-00188-00073008-00073399": "their decision was irreversible and that  once they'd made it, they could never", "cjF-wack7fk-00189-00073399-00073831": "change their mind.  We told the other half that they could", "cjF-wack7fk-00190-00073831-00074298": "exchange the poster they chose for a  different poster any time they wanted.", "cjF-wack7fk-00191-00074298-00074739": "After making their choices, we asked both  groups to rank their posters, and guess", "cjF-wack7fk-00192-00074739-00074954": "what?  The people who knew they couldn't", "cjF-wack7fk-00193-00074954-00075331": "exchange their posters liked them more  than the people who knew they could.", "cjF-wack7fk-00194-00075331-00075758": ">> [MUSIC] Why?  Because they had no choice,", "cjF-wack7fk-00195-00075758-00076169": "and so they adapted.   >> The lesson of this study was clear.", "cjF-wack7fk-00196-00076169-00076602": "People find ways to like things when  they're stuck with them.", "cjF-wack7fk-00197-00076602-00076982": "When we can't change our circumstances,  we change the way we think about those", "cjF-wack7fk-00198-00076982-00077306": "circumstances, and yet most of us don't seem to", "cjF-wack7fk-00199-00077306-00077668": "realize this will happen.   >> There is some set point to happiness", "cjF-wack7fk-00200-00077668-00078013": "that you tend to return toward.  And for some people, it's very happy, and", "cjF-wack7fk-00201-00078013-00078400": "for other people, it's mildly happy.  And, unfortunately, for a few people it", "cjF-wack7fk-00202-00078400-00078840": "may not be happy.  But, the set point is good in the sense", "cjF-wack7fk-00203-00078840-00079264": "that when we have something terrible in  our life happen to us, we get very", "cjF-wack7fk-00204-00079264-00079512": "depressed, we get less satisfied with our  life,", "cjF-wack7fk-00205-00079512-00079840": "but slowly over time, we come back toward  that set point.", "cjF-wack7fk-00206-00079840-00080404": ">> The question is what self-help  actually works and what self-help is", "cjF-wack7fk-00207-00080404-00080883": "false and doesn't work.   >> Psychologist Martin Seligman is a", "cjF-wack7fk-00208-00080883-00081217": "professor at the University of  Pennsylvania and one of the leaders of a", "cjF-wack7fk-00209-00081217-00081455": "new movement he calls Positive  Psychology.", "cjF-wack7fk-00210-00081455-00081948": ">> I realized that psychology had been  all about whining, and suffering, and", "cjF-wack7fk-00211-00081948-00082335": "anxiety, depression, victims, suicide,  drug addiction,", "cjF-wack7fk-00212-00082335-00082601": "and I had spent 35 years working on those  things.", "cjF-wack7fk-00213-00082601-00082934": "But that- that was half baked.  We're pretty good at misery,", "cjF-wack7fk-00214-00082934-00083302": "but what we weren't good at was what made  life worth living.", "cjF-wack7fk-00215-00083302-00083730": ">> What distinguishes positive  psychology from any other kind of self", "cjF-wack7fk-00216-00083730-00083953": "help?  According to Seligman, it isn't the", "cjF-wack7fk-00217-00083953-00084314": "message, but the method.   >> We do random assignment, placebo", "cjF-wack7fk-00218-00084314-00084794": "controlled studies, and ask, \"Does that  make people happier six months later", "cjF-wack7fk-00219-00084794-00085373": "and less depressed?\"  So this is an empirically based endeavor", "cjF-wack7fk-00220-00085373-00085855": "and a scientifically based endeavor.   >> Positive psychology has some very", "cjF-wack7fk-00221-00085855-00086289": "promising new ideas, but for now it's  probably fair to say that they need more", "cjF-wack7fk-00222-00086289-00086560": "testing.  Of course, some scientists think that the", "cjF-wack7fk-00223-00086560-00087089": "most promising ideas aren't new at all.  One of the best studied techniques for", "cjF-wack7fk-00224-00087089-00087557": "improving well being was developed not at  a clinic or a laboratory, but on a", "cjF-wack7fk-00225-00087557-00088038": "mountaintop 2,500 years ago.  [MUSIC]", "cjF-wack7fk-00226-00088038-00088606": ">> Meditation changes our relationship  to our thoughts and emotions.", "cjF-wack7fk-00227-00088606-00088902": ">> [MUSIC]  >> There's nothing magical about it.", "cjF-wack7fk-00228-00088902-00089489": "It's not mysterious. It can be addressed with the known", "cjF-wack7fk-00229-00089489-00089940": "mechanisms of science.   >> Psychologist Richard Davidson has", "cjF-wack7fk-00230-00089940-00090460": "been studying the benefits of meditation  since 1992, when the Dalai Lama invited", "cjF-wack7fk-00231-00090460-00090759": "him to India to measure the brain  activity of Buddhist monks.", "cjF-wack7fk-00232-00090919-00091561": ">> He had heard about me through mutual  friends and knew that I was a", "cjF-wack7fk-00233-00091561-00092308": "respectable, rigorous neuroscientist who  had interests in meditation, and he was", "cjF-wack7fk-00234-00092308-00092771": "interested in promoting scientific  research on meditation,", "cjF-wack7fk-00235-00092771-00093126": "and we thought that this would be an  amazing opportunity.", "cjF-wack7fk-00236-00093126-00093745": "We can bring portable equipment with us,  and schlep it up the mountain,", "cjF-wack7fk-00237-00093745-00094255": "and see if we can collect some data.  So we had quite a journey.", "cjF-wack7fk-00238-00094255-00094802": "We brought about 5000 pounds of equipment  with us.", "cjF-wack7fk-00239-00094802-00095357": ">> We looked like this crazy traveling  rock band with you know, these enormous", "cjF-wack7fk-00240-00095357-00095723": "cases.   >> Unfortunately, once Davidson was", "cjF-wack7fk-00241-00095723-00096071": "ready to collect the data, the monks had  a change of heart.", "cjF-wack7fk-00242-00096071-00096533": ">> They said they'd be happy to teach  us everything they know about meditation,", "cjF-wack7fk-00243-00096533-00096880": "but they didn't really want to do the  tests.", "cjF-wack7fk-00244-00096880-00097348": "But the Dalai Lama himself wanted to  continue fostering the dialogue between", "cjF-wack7fk-00245-00097348-00097745": "Buddhism and Western science.   >> This kind of a dialogue very", "cjF-wack7fk-00246-00097745-00098555": "helpful to expand human knowledge on this  not yet explored.", "cjF-wack7fk-00247-00098555-00099147": ">> And still vast subject. Our  knowledge very limited.", "cjF-wack7fk-00248-00099147-00099752": "So particularly about inner world, inner  signs, inner space.", "cjF-wack7fk-00249-00099752-00100162": "[MUSIC]   >> In 2000, the Dalai Lama began", "cjF-wack7fk-00250-00100162-00100563": "sending monks to Davidson's laboratory at  the University of Wisconsin, where they", "cjF-wack7fk-00251-00100563-00100919": "participated in a series of  neuropsychological studies.", "cjF-wack7fk-00252-00100919-00101335": "The results surprised Davidson, himself.   >> I thought about meditation as", "cjF-wack7fk-00253-00101335-00101826": "relaxation.  In fact, what we see in the brain of an", "cjF-wack7fk-00254-00101826-00102277": "advanced meditation practitioner when he  or she is meditating is heightened", "cjF-wack7fk-00255-00102277-00102816": "activation, not relaxation.   >> Davidson's studies of Buddhist monks", "cjF-wack7fk-00256-00102816-00103192": "and other experienced meditators  suggested that while they may appear to", "cjF-wack7fk-00257-00103192-00103571": "be resting, their minds are actually  intensely focused,", "cjF-wack7fk-00258-00103571-00103957": "and as they meditate more and more, their  brains begin to change.", "cjF-wack7fk-00259-00103957-00104472": "When Davidson compared scans of the monks  to scans of people who'd never meditated,", "cjF-wack7fk-00260-00104472-00104868": "he found that the monks showed  considerably more activity in the left", "cjF-wack7fk-00261-00104868-00105351": "prefrontal cortex, a part of the brain  that registers positive emotions.", "cjF-wack7fk-00262-00105351-00105741": "There are certain circuits in the brain  that are more sensitive to the processing", "cjF-wack7fk-00263-00105741-00106170": "of negative emotions and other circuits  that are more sensitive to the processing", "cjF-wack7fk-00264-00106170-00106636": "of positive emotions.  And more than any other organ in our", "cjF-wack7fk-00265-00106636-00107096": "body, the brain is built to change in  response to experience.", "cjF-wack7fk-00266-00107096-00107613": "It's a learning machine.  The scientific evidence suggests that", "cjF-wack7fk-00267-00107613-00108153": "we can actually train our mind and shape  its circuitry in our brain in very", "cjF-wack7fk-00268-00108153-00108578": "specific ways, to promote increased  levels of well being.", "cjF-wack7fk-00269-00108578-00109258": ">> I think scientific findings also  very, very useful, very convincing.", "cjF-wack7fk-00270-00109258-00110254": "It can be useful for magic of science, and also can be useful for bringing new", "cjF-wack7fk-00271-00110254-00111361": "generations more healthier minds, more  compassionate minds.", "cjF-wack7fk-00272-00111361-00111798": "[MUSIC]   >> So, is there a secret to happiness?", "cjF-wack7fk-00273-00111958-00112296": "Well, yes, but it isn't very much of a  secret.", "cjF-wack7fk-00274-00112296-00112572": "Scientific research suggests that a lot  of things matter:", "cjF-wack7fk-00275-00112572-00112981": "money, health, work, but that one thing  matters a lot,", "cjF-wack7fk-00276-00112981-00113602": "and that thing is social relationships.  We're one of the most social animals on", "cjF-wack7fk-00277-00113602-00113884": "our planet.  We need each other for just about", "cjF-wack7fk-00278-00113884-00114164": "everything.  So it isn't very surprising that nature's", "cjF-wack7fk-00279-00114164-00114522": "designed us to experience happiness when  we're connected to others:", "cjF-wack7fk-00280-00114522-00115393": "family, friends, lovers.  In fact, new evidence suggests that", "cjF-wack7fk-00281-00115393-00115653": "happiness may be as contagious as the  common cold.", "cjF-wack7fk-00282-00115653-00116127": "That it can be passed along from person  to person, and that it can travel farther", "cjF-wack7fk-00283-00116127-00116907": "and faster than anyone imagined.  [MUSIC] [SOUND] This is Framingham,", "cjF-wack7fk-00284-00116907-00117599": "Massachusetts.  In 1948, medical researchers began", "cjF-wack7fk-00285-00117599-00117981": "tracking the residents of this town,  trying to learn about the behaviors that", "cjF-wack7fk-00286-00117981-00118518": "cause heart disease.  [MUSIC] Their work continues today.", "cjF-wack7fk-00287-00118518-00118895": "Known as the Framingham Heart Study, it's  one of the world's most extensive", "cjF-wack7fk-00288-00118895-00119359": "epidemiological studies, containing six  decades worth of data on the health of", "cjF-wack7fk-00289-00119359-00119907": "more than 15,000 people.  And hidden in this mountain of data is a", "cjF-wack7fk-00290-00119907-00120378": "deep and powerful secret about the nature  of human happiness.", "cjF-wack7fk-00291-00120378-00121073": ">> Your happiness depends upon whole  large clusters of people you don't even", "cjF-wack7fk-00292-00121073-00121301": "know and- and who you have no way of  knowing.", "cjF-wack7fk-00293-00121301-00121795": ">> Nicholas Christakis is a physician  and a sociologist.", "cjF-wack7fk-00294-00121795-00122139": "He became interested in the Framingham  study not because he was interested in", "cjF-wack7fk-00295-00122139-00122568": "heart disease, but because he was  interested in social connections.", "cjF-wack7fk-00296-00122568-00122992": "These individuals had had their social  network ties repeatedly assessed over", "cjF-wack7fk-00297-00122992-00123365": "this 32 year period and, as it turns out,  had had various aspects of their", "cjF-wack7fk-00298-00123365-00123739": "emotional lives assessed as well.  So what we could tell is we could tell", "cjF-wack7fk-00299-00123739-00124215": "who these people were connected to every  four years or so for 30 years, and we", "cjF-wack7fk-00300-00124215-00124578": "could tell for example, whether they were  happy, or depressed, or lonely,", "cjF-wack7fk-00301-00124578-00124955": "and in some cases anxious repeatedly  across time.", "cjF-wack7fk-00302-00124955-00125448": ">> Using the Framingham data, Kristakas  and his colleagues mapped out a web of", "cjF-wack7fk-00303-00125448-00125891": "more than 50,000 connections between  friends, family, and coworkers who", "cjF-wack7fk-00304-00125891-00126366": "participated in the study.  Then they began to calculate how changes", "cjF-wack7fk-00305-00126366-00126781": "in the happiness of any single person  affected the happiness of others in this", "cjF-wack7fk-00306-00126781-00127135": "vast web of relationships.  The results were astounding.", "cjF-wack7fk-00307-00127135-00127702": "[MUSIC] What we found is that if your  friend becomes happy, it increases the", "cjF-wack7fk-00308-00127702-00128051": "probability that you will become happy by  about 15 percent.", "cjF-wack7fk-00309-00128051-00128298": "And if your friend's friend becomes  happy, someone you don't even know", "cjF-wack7fk-00310-00128298-00128742": "perhaps, it increases the probability  that you'll become happy by about 10 percent.", "cjF-wack7fk-00311-00128742-00128981": "It's only when we get to four degrees of  separation,", "cjF-wack7fk-00312-00128981-00129523": "only when we speaking of your  friend's friend's friend's friend that", "cjF-wack7fk-00313-00129523-00129904": "that person's emotional state is no  longer associated with your emotional", "cjF-wack7fk-00314-00129904-00130246": "state.   >> Everyone knows that people can make", "cjF-wack7fk-00315-00130246-00130633": "each other happy, but before this study, no one had any", "cjF-wack7fk-00316-00130633-00130870": "idea at just how powerful this effect  could be.", "cjF-wack7fk-00317-00130870-00131358": "[MUSIC] Kristakas' work shows that  happiness spreads through social networks", "cjF-wack7fk-00318-00131358-00131745": "like a virus.  That happiness is, in a very real sense,", "cjF-wack7fk-00319-00131745-00132167": "contagious.  There's no doubt about it. we're all", "cjF-wack7fk-00320-00132167-00132452": "connected, and those connections exert a powerful", "cjF-wack7fk-00321-00132452-00132893": "influence on our happiness.  We start out in highchairs, [MUSIC] we end", "cjF-wack7fk-00322-00132893-00133432": "up in wheel chairs, and somewhere between  the two, we all have to figure out where", "cjF-wack7fk-00323-00133432-00133683": "our happiness lies and then start marching in that", "cjF-wack7fk-00324-00133683-00133931": "direction.  So, who brought the map?", "cjF-wack7fk-00325-00133931-00134457": "Well, everyone did. Grandmothers and uncles, priests and", "cjF-wack7fk-00326-00134457-00134998": "rabbis, taxi drivers, bartenders,  motivational speakers-", "cjF-wack7fk-00327-00134998-00135274": "they all have something to say [MUSIC]  about happiness.", "cjF-wack7fk-00328-00135274-00135838": "But they don't all say the same thing.  And that's where science comes in.", "cjF-wack7fk-00329-00135838-00136281": "By using scientific methods to identify  the causes of human happiness, we're", "cjF-wack7fk-00330-00136281-00136683": "learning that the secret of happiness was  never very secret.", "cjF-wack7fk-00331-00136683-00137195": "We're connected to each other.  We belong to each other.", "cjF-wack7fk-00332-00137195-00137663": "Were made for each other.  Life is a journey through time, and", "cjF-wack7fk-00333-00137663-00137994": "happiness is what happens when we make  that journey together [MUSIC]."}}, {"audio_id": "cjI4z6N-Vjy", "text": {"cjI4z6N-Vjy-00000-00000883-00001653": "If you are going to spend energy for Guru-Vaiṣṇava   you can get Bhakti. Māyādevī cannot allow you to do.", "cjI4z6N-Vjy-00001-00001653-00002478": "Māyādevī is always planning the situation in such a way that  you can get deviated from Bhakti–Prabhupāda speaking.", "cjI4z6N-Vjy-00002-00002478-00003675": "Māyādevī is always making the program in such a way so you   are bound to fall down. Māyādevī making different programs.", "cjI4z6N-Vjy-00003-00003675-00004336": "Māyādevī is making different programs: website,   internet–all–naked picture. Everything in web you can get.", "cjI4z6N-Vjy-00004-00004336-00005424": "All! \"Māyādevī is making plotting, so that Māyādevī can   deviate you from bhajan\", Prabhupāda speaking.", "cjI4z6N-Vjy-00005-00005424-00005847": "That is why fighting; otherwise, why are they fighting?", "cjI4z6N-Vjy-00006-00005847-00006631": "Prabhupāda is speaking, \"Māyādevī is planning the   program in such a way so that you can lose your bhajan.", "cjI4z6N-Vjy-00007-00006631-00007185": "Because at all if you are going to give your energy for   Guru-Vaiṣṇava-Bhagavān, then automatically you can", "cjI4z6N-Vjy-00008-00007185-00007816": "come out successfully in your bhajan. So, surely Māyādevī   cannot allow you.\" Ha, Māyādevī cannot allow you,", "cjI4z6N-Vjy-00009-00007816-00008273": "but you are going to hold on... if you are going   to hold on the lotus feet of Guru-Vaiṣṇava,", "cjI4z6N-Vjy-00010-00008273-00008744": "\"Ok! Let me see how much force Māyādevī applies?!\"", "cjI4z6N-Vjy-00011-00008744-00008987": "Finally Māyādevī is going to get defeated.", "cjI4z6N-Vjy-00012-00008987-00009638": "Mayare koriyā jaya chāḍāno nā yāya  sādhu guru kṛpā vinā na dekhi upāya", "cjI4z6N-Vjy-00013-00009638-00010382": "Without kṛpā of Sādhu-Guru-Vaiṣṇava,   full blessing, [there is] no way out.", "cjI4z6N-Vjy-00014-00010382-00011266": "You cannot get victory over Māyā. Māyādevī willingly...   Māyādevī herself willingly can leave you: \"Ok!\"", "cjI4z6N-Vjy-00015-00011266-00012047": "Because in Bhāgavatam Bhagavān Śrī Kṛṣṇa is giving advice to  Uddhava, \"Uddhava! Those who are going to do Hari-bhajan.", "cjI4z6N-Vjy-00016-00012047-00012668": "Finally Māyādevī can leave you, but not before!\"", "cjI4z6N-Vjy-00017-00012668-00013312": "Bhagavān Śrī Kṛṣṇa is speaking to Uddhava, \"Uddhava!   Those who are taking resolution... Uddhava!", "cjI4z6N-Vjy-00018-00013312-00013825": "Those who are going to take resolution   to do Kṛṣṇa-sevā, Hari-bhajan...", "cjI4z6N-Vjy-00019-00013825-00014653": "All demigods and Māyādevī can kick you. Heh.   Kick from here to there–here to there–kick always.", "cjI4z6N-Vjy-00020-00014653-00015671": "Like football. Finally if they discover he has tremendous   love for Guru-Vaiṣṇava. Without Guru-Vaiṣṇava he cannot", "cjI4z6N-Vjy-00021-00015671-00016495": "(he or she cannot) live. If they can discover,   then they can bless you and go away: \"Ok!\"", "cjI4z6N-Vjy-00022-00016500-00017065": "First of all no entry, no entry in   Hari-bhajan: \"Stay outside!\"", "cjI4z6N-Vjy-00023-00017065-00017826": "After that, when they are going to discover the   abnormal extraordinary quality in you for Guru-bhajan,", "cjI4z6N-Vjy-00024-00017826-00018774": "love for Guru-Vaiṣṇava, they can open the   gate: \"You go!\" They can allow you entry."}}, {"audio_id": "cjP5eS31Zcg", "text": {"cjP5eS31Zcg-00000-00000016-00000344": "yo guys welcome back to the channel but like a pimp because i'm", "cjP5eS31Zcg-00001-00000488-00000984": "yeah so this is my room tour uh i fell off balance so this is being requested", "cjP5eS31Zcg-00002-00000984-00001240": "a couple of times on the channel in the comments section you guys have wanted", "cjP5eS31Zcg-00003-00001240-00001639": "to see a room tour for some odd reason i don't know but i had it but i had it but", "cjP5eS31Zcg-00004-00001912-00002296": "i also had our idea to do this video because i wanted to be like a little bit of history", "cjP5eS31Zcg-00005-00002296-00002760": "i'm planning to move out of this office space in this area in 2021 whether or not i'm still", "cjP5eS31Zcg-00006-00002760-00003192": "living in this actual house or not i want to have like an external space so i can do work", "cjP5eS31Zcg-00007-00003192-00003600": "focus on the business and just have another sort of room where i can do a lot of my work because i", "cjP5eS31Zcg-00008-00003600-00004008": "feel like it would be beneficial for the business side of things just to have an external space", "cjP5eS31Zcg-00009-00004008-00004400": "whether it's an office or another bedroom wherever i move house who really cares but yeah this is the", "cjP5eS31Zcg-00010-00004400-00005032": "official 2020 room tour i guess is that necessary is that necessary is that necessary yeah this", "cjP5eS31Zcg-00011-00005032-00005632": "is it the room tour let's just start it off so first you come in um this is my light switch it's", "cjP5eS31Zcg-00012-00005632-00006240": "actually this is a design function um it's so you can yeah it's portable so like if you wanted to be", "cjP5eS31Zcg-00013-00006240-00006559": "up here and you wanted to turn the light on and off you could do that but i let it hang you know", "cjP5eS31Zcg-00014-00006672-00007128": "definitely not just laziness when the room was getting redone this over here as you guys can see", "cjP5eS31Zcg-00015-00007128-00007688": "there's a lot to go through but is what isn't it this is my wardrobe a lot of people have requested", "cjP5eS31Zcg-00016-00007688-00008280": "like yo yo where'd you get that wardrobe is it ikea built no fam me and my dad grafted in it", "cjP5eS31Zcg-00017-00008280-00008888": "so yeah my dad custom built this wardrobe for me luckily and um luckily how did i say this", "cjP5eS31Zcg-00018-00008888-00009632": "i'm fortunate enough to have a dad who you know just to have a dad but yeah we put this together", "cjP5eS31Zcg-00019-00009632-00010000": "ourselves he did a lot of the work custom built wardrobe i had a designer had a plan but i just", "cjP5eS31Zcg-00020-00010000-00010392": "wanted to have a space where i could hang all of my clothes with my favorite clothes that i like", "cjP5eS31Zcg-00021-00010392-00010824": "to wear and then also have some storage space around the top predominantly four shoes as you", "cjP5eS31Zcg-00022-00010824-00011248": "guys can see we still got some tango ice blasts from a video that did very well this year so", "cjP5eS31Zcg-00023-00011304-00011648": "keep that as a memory but if you guys want one i'll sell them on depop for like two pounds but", "cjP5eS31Zcg-00024-00011648-00012136": "yeah uh let's run through some stuff we got my vans here just some air forces i", "cjP5eS31Zcg-00025-00012136-00012488": "think these yeah these are the ones that are customized also earlier in the year they're", "cjP5eS31Zcg-00026-00012576-00013000": "battered right now because they're the only show i really wear uh what else have we got we got the", "cjP5eS31Zcg-00027-00013000-00013391": "childish hoodie tin although the childhood is hanging up because i feel like a little", "cjP5eS31Zcg-00028-00013391-00013919": "bit of purple will spice up my life we've got my jordans we got the yeezys that ramel gave me we", "cjP5eS31Zcg-00029-00013919-00014328": "also got these these are these shoes actually haven't been released to the public yet um", "cjP5eS31Zcg-00030-00014656-00014968": "yeah we also have these ones that also haven't been released to the public", "cjP5eS31Zcg-00031-00014968-00015391": "what shoes what boxes i think they're in are they in this air force box no where are they where are", "cjP5eS31Zcg-00032-00015391-00015784": "they these shoes also haven't been released to the public as well these are the new yeezys", "cjP5eS31Zcg-00033-00015904-00016352": "yeah they're this time night yeah night yeezys yeah yeah yeah they haven't been released so", "cjP5eS31Zcg-00034-00016352-00016800": "everyone keep your mouth shut about that in the comments but yeah that's that's really it for this", "cjP5eS31Zcg-00035-00016800-00017352": "what no two ways oh yeah yeah yeah we also got these um no two ways you guys know kallux galaxy's", "cjP5eS31Zcg-00036-00017352-00017824": "shoe company no two ways i didn't actually get a chance to get moonless right but i'm looking", "cjP5eS31Zcg-00037-00017824-00018168": "for them on resale but they're going for a bit hi i've got these on resale i didn't actually", "cjP5eS31Zcg-00038-00018168-00018792": "cop these on the drop yeah i paid like 160 or 140 for these resell on depop just to film that video", "cjP5eS31Zcg-00039-00018792-00019336": "so you guys see i don't put effort into videos yeah i spent like 140 pounds on that video we got", "cjP5eS31Zcg-00040-00019336-00019952": "this build-a-bear this is this is my girlfriend as a bear no that's just your girlfriend yep", "cjP5eS31Zcg-00041-00020160-00020448": "we have my underpants hi show us okay", "cjP5eS31Zcg-00042-00020736-00021048": "don't look that's going to be sensitive that's going to be censored no no and then yeah that's it", "cjP5eS31Zcg-00043-00021048-00021480": "we have my hat collection here not really anything special just some hats that i like to wear from", "cjP5eS31Zcg-00044-00021480-00021920": "time to time we have this extra small hoodie from batson clothing that unfortunately didn't", "cjP5eS31Zcg-00045-00021920-00022288": "sell out so if you guys want an extra small yeah me and i'll just send it to you for free i don't", "cjP5eS31Zcg-00046-00022288-00022752": "really care because i have a bag of supreme stuff that ramel sent me um in the mystery unboxing", "cjP5eS31Zcg-00047-00022752-00023112": "video if you haven't seen that already go ahead and watch that video and yeah just some other", "cjP5eS31Zcg-00048-00023112-00023808": "bits and bobs i like to keep this space spice i like to keep this i like to keep this space sort", "cjP5eS31Zcg-00049-00023808-00024216": "of really tidy because i don't like having a messy room although it gets messy from time to time", "cjP5eS31Zcg-00050-00024216-00024672": "um once a week i'll do like a big clean out and it just makes me feel so refreshed", "cjP5eS31Zcg-00051-00025040-00025496": "behind me there's nothing there we have my bags here nothing too interesting", "cjP5eS31Zcg-00052-00025736-00026112": "let's move on as we come around here oh yeah by the way guys my room", "cjP5eS31Zcg-00053-00026112-00026448": "is tiny like i don't know if you guys can tell like watch watch watch", "cjP5eS31Zcg-00054-00026656-00026960": "like that didn't take very long tonight i mean it's a very small room so", "cjP5eS31Zcg-00055-00026960-00027576": "yeah that's it the majority of my room is my bed my lovely lovely dubli bid this is a plant no", "cjP5eS31Zcg-00056-00027704-00028104": "yeah did you not know this is my bedside table got loads of stuff in here that you", "cjP5eS31Zcg-00057-00028104-00028520": "guys probably won't find important blah blah blah advent calendar because it's christmas you know", "cjP5eS31Zcg-00058-00028639-00029144": "gotta stay fat on that we also have this plant here uh also fake however this is where things", "cjP5eS31Zcg-00059-00029144-00029695": "get important this is this is spicy this is where things get spicy this is the part of", "cjP5eS31Zcg-00060-00029768-00030160": "this is the part of my room that no one ever sees apart from now obviously", "cjP5eS31Zcg-00061-00030160-00030552": "because my camera is usually here facing that direction this is where everything happens this", "cjP5eS31Zcg-00062-00030552-00031039": "is the bread and the bar this is the foundation of this youtube channel right here so let's let's", "cjP5eS31Zcg-00063-00031039-00031400": "go through it right start for the obvious we have a whiteboard i feel like it's really important in", "cjP5eS31Zcg-00064-00031400-00031832": "life to set some goals because you have something to actually work towards so as you can see here", "cjP5eS31Zcg-00065-00031832-00032552": "in august of 2021 um or no august of 2020 i wrote these goals down and in one year so", "cjP5eS31Zcg-00066-00032552-00032952": "august 2021 is when i want to accomplish them buy so i've under k on youtube", "cjP5eS31Zcg-00067-00032952-00033520": "i've have made over 10 000 pounds or dollars from clothing have one million plus views", "cjP5eS31Zcg-00068-00033520-00033984": "not be working in sainsburys have an online income of over 10 000 pounds a year because", "cjP5eS31Zcg-00069-00033984-00034456": "let's be real money makes a walk around you have to sort of make money for it to be sustainable be", "cjP5eS31Zcg-00070-00034456-00035184": "moving out and be happy two of the most important things who is calling me right now yo jay hi", "cjP5eS31Zcg-00071-00036520-00036768": "yeah so as i was saying it's important to set goals and by", "cjP5eS31Zcg-00072-00036840-00037296": "in like so what is it like maybe nine or eleven nine or ten months now because it's been a couple", "cjP5eS31Zcg-00073-00037296-00037704": "months since i wrote these that's i want to have them goals all ticked off what eight months eight", "cjP5eS31Zcg-00074-00037704-00038128": "months from now i want to have them go sticked off so yeah and we have some exclusives don't", "cjP5eS31Zcg-00075-00038128-00038528": "watch that don't watch that don't watch that dotbatson.com as you guys know i recently wiped", "cjP5eS31Zcg-00076-00038528-00038912": "this off and made it a bit more neater because it was so clunky and there was just so much", "cjP5eS31Zcg-00077-00038912-00039240": "that i didn't need so yeah it's looking a bit empty now but it's going to get filled", "cjP5eS31Zcg-00078-00039240-00039640": "up very very soon and this talk about this feature of the room here oh yeah yeah so", "cjP5eS31Zcg-00079-00039640-00040104": "this is where i do some i do acrobatics from here i'll show you a little example", "cjP5eS31Zcg-00080-00040456-00041136": "yeah so that's all i do all day yeah just swing from there yeah you can see the room is", "cjP5eS31Zcg-00081-00041136-00041824": "season finished because we got lazy but then we get to the real real meat the real beef burger", "cjP5eS31Zcg-00082-00041824-00042232": "now we get into the real juicy stuff all right this is where the magic happens everything that", "cjP5eS31Zcg-00083-00042232-00042792": "you guys don't see happens here the edit in the design process for basically everything", "cjP5eS31Zcg-00084-00042792-00043232": "is done at this desk and has always been done at this desk so let's run for everything", "cjP5eS31Zcg-00085-00043232-00043712": "this is a wacom back on pad basically like a graphic tablet so you can draw on it and", "cjP5eS31Zcg-00086-00043712-00044096": "it goes straight to the laptop so if you guys want to know how i created the sketchy", "cjP5eS31Zcg-00087-00044096-00044544": "it was all done on not this specific tablet but it was all done on this wacom tablet so", "cjP5eS31Zcg-00088-00044544-00045096": "everything was hand drawn this is a little tripod nothing really interesting there this microphone", "cjP5eS31Zcg-00089-00045096-00045648": "i've never really used it to be honest i use it maybe once on a dropouts video um that's it really", "cjP5eS31Zcg-00090-00045648-00046056": "just talk to people on discord this is another monitor for when i want to have like an extra", "cjP5eS31Zcg-00091-00046056-00046576": "screen for something say for example i'm streaming and i want to have like my what's it called my obs", "cjP5eS31Zcg-00092-00046576-00047064": "open on here really really handy i should really suggest like if you're into video production or", "cjP5eS31Zcg-00093-00047064-00047488": "production of any sort that happens on a computer having a second monitor is always really helpful", "cjP5eS31Zcg-00094-00047488-00047920": "because it allows you to expand your workspace and have everything cramped into windows so you have", "cjP5eS31Zcg-00095-00047920-00048408": "to keep opening your clothes and everything it's really helpful this is my 2020 macbook air before", "cjP5eS31Zcg-00096-00048408-00048912": "this i had like a i think it's like a 2017 macbook air really really good but i felt like i needed to", "cjP5eS31Zcg-00097-00048912-00049472": "upgrade a little bit because you know times are changing so this is my 2020 macbook air all every", "cjP5eS31Zcg-00098-00049472-00050000": "single one of my videos from like how long ago from ages ago has been edited on this one laptop", "cjP5eS31Zcg-00099-00050000-00050448": "it's done me wonders and it's really lightweight and really portable and i basically take it", "cjP5eS31Zcg-00100-00050448-00050848": "everywhere with me so that's that now this i don't want to unplug because last time i unplugged the", "cjP5eS31Zcg-00101-00050848-00051400": "hard drive without ejecting it i lost everything this is on my one terabyte hard drive and it is", "cjP5eS31Zcg-00102-00051464-00051864": "basically the key to my life like it has everything more or less that i've ever made", "cjP5eS31Zcg-00103-00051864-00052288": "on it and as soon as this hard drive gets filled up i'm gonna get a new one because i don't want to", "cjP5eS31Zcg-00104-00052288-00052824": "delete anything i ever do basically it has all the raw footage from like in my past 20 videos", "cjP5eS31Zcg-00105-00052928-00053272": "guys if you're into video production and you want to make a youtube channel if you can afford it", "cjP5eS31Zcg-00106-00053272-00053728": "all right storage is key make sure you have hard drives on hard drives hard drives up everything", "cjP5eS31Zcg-00107-00053728-00054200": "back up everything okay because one time i lost everything on a hard drive and i had to basically", "cjP5eS31Zcg-00108-00054200-00054655": "restart from scratch so that was [ ] bad that's it really if you take a look underneath you've", "cjP5eS31Zcg-00109-00054655-00055120": "got our ps4 that isn't even plugged in i don't play ps4 anymore you have my speakers that are", "cjP5eS31Zcg-00110-00055120-00055584": "also attached to speakers there that also go to the back of the room you can see their speakers", "cjP5eS31Zcg-00111-00055584-00056120": "in the top corners um they don't really do much you're way too close i can tell this is so close", "cjP5eS31Zcg-00112-00056120-00056624": "to my face uh yeah that's it really nothing really has to go into like i've got a printer", "cjP5eS31Zcg-00113-00056624-00057024": "who the [ __ ] is that yeah guys that's it for this video um if there's anything else you want me", "cjP5eS31Zcg-00114-00057024-00057664": "to do leave it in the comment section down below um maybe you could influence the next video bye"}}, {"audio_id": "ckCzvOGhdvu", "text": {"ckCzvOGhdvu-00000-00000000-00000512": "1. Open the game;", "ckCzvOGhdvu-00001-00001984-00002592": "2. Open the GameGuardian and select \"Start\";", "ckCzvOGhdvu-00002-00003056-00003432": "3. See the amount of energy of your Sim;", "ckCzvOGhdvu-00003-00003679-00004047": "4. Select \"The Sims\" per GameGuardian and select the \"magnifying glass\" icon;", "ckCzvOGhdvu-00004-00004120-00004592": "5. Edit the \"Value =\" equal to the current energy of your Sim and select the \"Type:\" to \"D: Dword\" and press on \"NEW SEARCH\";", "ckCzvOGhdvu-00005-00005696-00006576": "6. Use one or more power points and return to GameGuardian by filling in the \"Value =\" for your current energy and press \"REFINE\";", "ckCzvOGhdvu-00006-00007072-00007912": "7. If there are not one or two options remaining. redo step 7;", "ckCzvOGhdvu-00007-00008232-00009432": "8. Activate \"Freeze:\" and change from \"normal\" to \"may increase\", finally edit \"Value =\" to 30.", "ckCzvOGhdvu-00008-00010034-00010146": "BYE"}}, {"audio_id": "ckYi_DoQjOQ", "text": {"ckYi_DoQjOQ-00000-00000000-00000588": "Female copulatory vocalisation refers to the natural phenomenon of women being \"loud\" in bed.", "ckYi_DoQjOQ-00001-00000588-00001150": "In evolutionary terms, it's only like yesterday that human beings lived as hunter-gatherers in tribes.", "ckYi_DoQjOQ-00002-00001150-00001692": "With the joyous, sexual screams the woman was letting her surroundings know that she was getting it on.", "ckYi_DoQjOQ-00003-00001692-00002018": "By being \"loud\" she attracted the attention of the men of the tribe", "ckYi_DoQjOQ-00004-00002018-00002430": "who would flock to the scene. Then she would mate with each and everyone of them, in a row.", "ckYi_DoQjOQ-00005-00002430-00003058": "In doing so, she would accumulate sperm from different men in her vagina, where then \"sperm competition\" took place.", "ckYi_DoQjOQ-00006-00003240-00003488": "May the best sperm fertilize the egg.", "ckYi_DoQjOQ-00007-00003488-00004044": "Herewith, chances of conceiving healthy, fertile babies were increased by the millions", "ckYi_DoQjOQ-00008-00004044-00004604": "as opposed to selectively chosing a sexual partner and future parent for your children.", "ckYi_DoQjOQ-00009-00004648-00004992": "And that's why women are natural born noisemakers!"}}, {"audio_id": "clQBwzWA3Ry", "text": {"clQBwzWA3Ry-00000-00001100-00001800": "RYGB is an effective treatment to combat obesity, here's why", "clQBwzWA3Ry-00001-00001900-00002820": "RYGB is an effective treatment to combat obesity, here's why. Obesity is a growing epidemic worldwide and is one major risk factor for asthma. It is also a leading cause of death alongside heart disease and smoking.", "clQBwzWA3Ry-00002-00002920-00003620": "Bariatric surgery, specifically Roux-en-Y gastric bypass (RYGB), is the most effective treatment for obesity.", "clQBwzWA3Ry-00003-00003720-00004420": "With RYGB many patients exhibit a reduction in taste preference for sweet and fatty foods, although this effect may only be temporary, according to a new research from Binghamton University, State University of New York.", "clQBwzWA3Ry-00004-00004520-00005420": "Professor Patricia DiLorenzo said, \"People who have this surgery are what we call morbidly obese, meaning that they are at least 100 pounds overweight, and in many cases are diabetic. It's life or death for them.\".", "clQBwzWA3Ry-00005-00005520-00006440": "RYGB makes the stomach much smaller into what is called a pouch. This pouch bypasses part of the small intestine, so when you eat, your food enters a smaller stomach and empties right into the small intestine.", "clQBwzWA3Ry-00006-00006540-00007520": "This means that people cannot eat large meals anymore, leading to weight loss. However, taste and odour preferences are also known to change after surgery, and their potential involvement with the noted weight loss is a question of the study.", "clQBwzWA3Ry-00007-00007620-00008320": "DiLorenzo and her research team investigated food and odour preference changes following RYGB and compared them to changes in body-mass index (BMI) post-surgery.", "clQBwzWA3Ry-00008-00008420-00009120": "The research team also found that people who liked coffee more post-surgery were also the people that lost the most weight.", "clQBwzWA3Ry-00009-00009220-00009920": "Coffee and vegetables share a bitter flavor, indicating that post-RYGB surgery, some patients' taste preferences shifted from high-fat and sweet foods to ones where bitter tastes were less aversive.", "clQBwzWA3Ry-00010-00010020-00010720": "Patients who experienced this effect lost the most weight and had lower BMI in the long run after surgery.", "clQBwzWA3Ry-00011-00010820-00011520": "However, these altered food preferences generally trend back towards pre-surgery preferences over time. Additionally, the rate of weight loss lessens as time increases post-surgery.", "clQBwzWA3Ry-00012-00011620-00012320": "Despite the risk for some patients to regain weight post-surgery, the majority of patients successfully lose and keep the weight off. The study is presented in the journal- PLOS ONE."}}, {"audio_id": "cm3cAgDC43y", "text": {"cm3cAgDC43y-00000-00000654-00001026": "Welcome to draw tip tuesday", "cm3cAgDC43y-00001-00001026-00001590": "I live in Amsterdam, and therefore, I am surrounded by bicycles, I often draw them.", "cm3cAgDC43y-00002-00001590-00002027": "I hear a lot people say: bicycles are SO hard to draw!", "cm3cAgDC43y-00003-00002027-00002238": "But are they really?", "cm3cAgDC43y-00004-00002238-00002532": "Like drawing anything: it’s just shapes and lines.", "cm3cAgDC43y-00005-00002532-00002860": "So here’s what I do when I draw a bicycle.", "cm3cAgDC43y-00006-00002860-00003049": "First I outline the whole thing.", "cm3cAgDC43y-00007-00003049-00003706": "I don’t worry about the wheels being perfectly rounded, in fact, I don’t even look at the", "cm3cAgDC43y-00008-00003706-00004196": "wheels, the frame, and all the individual details on the bicycle.", "cm3cAgDC43y-00009-00004196-00004813": "I look at the shape that I see, trace it with my eyes and let my hand trace it too.", "cm3cAgDC43y-00010-00004813-00005317": "Of course, this needs a little bit of practice.", "cm3cAgDC43y-00011-00005317-00005862": "The more you do this, drawing anything really, the more comfortable you will get doing it.", "cm3cAgDC43y-00012-00005862-00006417": "Don’t think of the end result, just look at it as an exercise, training your eye-hand", "cm3cAgDC43y-00013-00006417-00006681": "coordination.", "cm3cAgDC43y-00014-00006681-00006834": "Once I’ve traced the outline.", "cm3cAgDC43y-00015-00006834-00007273": "I am still not looking at the shape of the bicycle.", "cm3cAgDC43y-00016-00007273-00007630": "Now I focus on all the shapes that I see, that are NOT bicycle.", "cm3cAgDC43y-00017-00007630-00008312": "In the image, it’s not that hard, because the photo has a bright white background, and", "cm3cAgDC43y-00018-00008312-00008864": "all I need to focus on, are these white shapes that I see, and draw these.", "cm3cAgDC43y-00019-00008864-00009549": "So I take a very close look at the negative spaces that I see, I look at their shapes", "cm3cAgDC43y-00020-00009549-00010056": "and the proportions between them, and as I draw them, the shape of the bicycle starts", "cm3cAgDC43y-00021-00010056-00019288": "to appear between all that.", "cm3cAgDC43y-00022-00019288-00019833": "Once I drew all those negative shapes in, I start looking at the details, connecting", "cm3cAgDC43y-00023-00019833-00020437": "lines of the bike frame, adding some detail here and there, until it looks right.", "cm3cAgDC43y-00024-00020437-00020795": "The wheels are kind of wobbly, but I don’t mind.", "cm3cAgDC43y-00025-00020795-00021799": "It adds personality.", "cm3cAgDC43y-00026-00021799-00022218": "So now all this needs is a bit of color to bring it to life.", "cm3cAgDC43y-00027-00022218-00022720": "Now, I know you may think: „You make it look so simple, Koosje!”.", "cm3cAgDC43y-00028-00022720-00023263": "Maybe so, but with practice and patience, you can do this too.", "cm3cAgDC43y-00029-00023263-00023764": "Maybe you could try this technique with simple shapes first, looking at the negative spaces", "cm3cAgDC43y-00030-00023764-00023934": "inside of the shape.", "cm3cAgDC43y-00031-00023934-00024527": "And, if you would like more help, have a look at my website koosjekoene.nl and join one", "cm3cAgDC43y-00032-00024527-00024927": "of my classes!"}}, {"audio_id": "cm4qxl8q0UY", "text": {"cm4qxl8q0UY-00000-00000508-00000734": "I am a preacher today", "cm4qxl8q0UY-00001-00000869-00001076": "and I'm a sinner tonight", "cm4qxl8q0UY-00002-00001244-00001426": "just look what I've done", "cm4qxl8q0UY-00003-00001688-00001902": "angel of love is gone", "cm4qxl8q0UY-00004-00001992-00002240": "I am angel of decay", "cm4qxl8q0UY-00005-00002382-00002602": "sitting on the black horse", "cm4qxl8q0UY-00006-00002808-00002996": "praying to God of lie", "cm4qxl8q0UY-00007-00003182-00003468": "and trying to take your souls", "cm4qxl8q0UY-00008-00004974-00005128": "Black face, white walls", "cm4qxl8q0UY-00009-00005128-00005284": "so close to me", "cm4qxl8q0UY-00010-00005284-00005474": "it's your choice, your way", "cm4qxl8q0UY-00011-00005474-00005644": "so walk with me", "cm4qxl8q0UY-00012-00005644-00005764": "you want money", "cm4qxl8q0UY-00013-00005764-00005876": "want glory", "cm4qxl8q0UY-00014-00005876-00006018": "want sex and pain", "cm4qxl8q0UY-00015-00006018-00006160": "I'll give you everything", "cm4qxl8q0UY-00016-00006204-00006354": "everything you want", "cm4qxl8q0UY-00017-00006406-00007098": "sticky madness", "cm4qxl8q0UY-00018-00007120-00007442": "I am your teacher today", "cm4qxl8q0UY-00019-00007556-00007759": "and I'm your lover tonight", "cm4qxl8q0UY-00020-00007936-00008095": "just look what you've done", "cm4qxl8q0UY-00021-00008308-00008444": "you lose everything", "cm4qxl8q0UY-00022-00008634-00008914": "now you are crying", "cm4qxl8q0UY-00023-00008998-00009266": "and I'm choking with laughter", "cm4qxl8q0UY-00024-00009346-00009684": "nobody is to blame", "cm4qxl8q0UY-00025-00009754-00010044": "black face, white walls again", "cm4qxl8q0UY-00026-00010092-00010292": "Black face, white walls", "cm4qxl8q0UY-00027-00010292-00010468": "so close to me", "cm4qxl8q0UY-00028-00010468-00010666": "it's your choice, your way", "cm4qxl8q0UY-00029-00010666-00010816": "so walk with me", "cm4qxl8q0UY-00030-00010832-00011032": "you want money, want glory", "cm4qxl8q0UY-00031-00011032-00011232": "want sex and pain", "cm4qxl8q0UY-00032-00011232-00011412": "I'll give you everything", "cm4qxl8q0UY-00033-00011412-00011620": "everything you want", "cm4qxl8q0UY-00034-00011632-00011814": "Black face, white walls", "cm4qxl8q0UY-00035-00011820-00011984": "so close to me", "cm4qxl8q0UY-00036-00012004-00012180": "it's your choice, your way", "cm4qxl8q0UY-00037-00012180-00012276": "so walk with me", "cm4qxl8q0UY-00038-00012334-00012430": "you want money", "cm4qxl8q0UY-00039-00012462-00012534": "want glory", "cm4qxl8q0UY-00040-00012552-00012646": "want sex and pain", "cm4qxl8q0UY-00041-00012706-00012840": "I'll give you everytnig", "cm4qxl8q0UY-00042-00012844-00012980": "everything you want"}}, {"audio_id": "cmQYgRf1hK8", "text": {"cmQYgRf1hK8-00000-00000000-00000050": "help...", "cmQYgRf1hK8-00001-00000066-00000115": "robin, you're fucking useless", "cmQYgRf1hK8-00002-00000180-00000519": "kill yourself robin, you have ropes next to you", "cmQYgRf1hK8-00003-00000694-00000892": "everybody hates you robin", "cmQYgRf1hK8-00004-00002134-00002311": "you fucking whore"}}, {"audio_id": "cmZfJpSNh8o", "text": {"cmZfJpSNh8o-00000-00000142-00000597": "hi everyone that's Jean Hanson co-founder of the janitorial store calm", "cmZfJpSNh8o-00001-00000597-00001038": "and I'm here with another janitorial supervisor training tip today I want to", "cmZfJpSNh8o-00002-00001038-00001533": "talk about motivating and engaging employees in the job I know that", "cmZfJpSNh8o-00003-00001533-00001998": "recruiting is a huge problem these days but if you've got some good employees on", "cmZfJpSNh8o-00004-00001998-00002439": "staff you have got to pay attention to them you've got to keep them motivated", "cmZfJpSNh8o-00005-00002439-00002810": "you've got to get them engaged in their job or you're gonna lose them and you're", "cmZfJpSNh8o-00006-00002810-00003165": "gonna be in even worse trouble than you are right now they're not being able to", "cmZfJpSNh8o-00007-00003165-00003627": "find new employees so here's a few of the things that you can do and the", "cmZfJpSNh8o-00008-00003627-00004032": "easiest thing you can do is simply recognize that for doing a good job I", "cmZfJpSNh8o-00009-00004032-00004464": "mean it just feels good to have someone recognize the work that you're doing", "cmZfJpSNh8o-00010-00004464-00004986": "right I mean it feels good for me and I know it feels good for my employees as", "cmZfJpSNh8o-00011-00004986-00005637": "well respect and Trust goes a long ways towards keeping good employees now as a", "cmZfJpSNh8o-00012-00005637-00006153": "general supervisors a lot of times you know the supervisors want to earn", "cmZfJpSNh8o-00013-00006153-00006756": "respect and Trust but you can't earn it unless you give it right so trust your", "cmZfJpSNh8o-00014-00006756-00007218": "employees respect your employees you don't know what they're going through in", "cmZfJpSNh8o-00015-00007218-00007731": "their own lives and so having a dedicated hard-working employee deserves", "cmZfJpSNh8o-00016-00007731-00008204": "your respect and Trust giving them some extra responsibilities now I'm not", "cmZfJpSNh8o-00017-00008204-00008559": "talking about dumping the job so you don't like to do on now I'm talking", "cmZfJpSNh8o-00018-00008559-00008946": "about just giving them some simple responsibilities that makes them feel", "cmZfJpSNh8o-00019-00008946-00009425": "important right it could be as simple as welcoming in a new employee", "cmZfJpSNh8o-00020-00009425-00009906": "it could be handling a special request from a client doesn't have to be a big", "cmZfJpSNh8o-00021-00009906-00010284": "deal but give them a little bit of responsibility and then make sure that", "cmZfJpSNh8o-00022-00010284-00010739": "you recognize them when they do a good job with it another thing that's", "cmZfJpSNh8o-00023-00010739-00011127": "important to people is to be informed you know just because you're a", "cmZfJpSNh8o-00024-00011127-00011685": "janitorial supervisor that or maybe you have some new janitorial supervisors", "cmZfJpSNh8o-00025-00011685-00012047": "this is a good thing to remind them of is that just because you might be privy", "cmZfJpSNh8o-00026-00012047-00012492": "to certain information doesn't mean you should live that over your employee", "cmZfJpSNh8o-00027-00012492-00012781": "saying ah something you don't know or you don't", "cmZfJpSNh8o-00028-00012781-00013173": "need to know that you know make sure that you keep them informed on the", "cmZfJpSNh8o-00029-00013173-00013654": "things that they need to know people just want to feel like you're being", "cmZfJpSNh8o-00030-00013654-00013981": "honest with them like you're being upfront that you're trusting them with", "cmZfJpSNh8o-00031-00013981-00014575": "information okay also make sure that you are soliciting their feedback people", "cmZfJpSNh8o-00032-00014575-00014926": "want to make suggestions if they see something that isn't working correctly", "cmZfJpSNh8o-00033-00014926-00015355": "but if you're always shutting down their ideas they're never gonna speak up", "cmZfJpSNh8o-00034-00015355-00015681": "they're just gonna let things go on and maybe they have a great idea to save", "cmZfJpSNh8o-00035-00015681-00016186": "some time or increase profits or make your life easier right so encourage that", "cmZfJpSNh8o-00036-00016186-00016594": "feedback and then listen to them and thank them and let them know that you", "cmZfJpSNh8o-00037-00016594-00016879": "appreciate that that you're going to talk with your bosses and maybe you can", "cmZfJpSNh8o-00038-00016879-00017416": "implement some of those ideas so one of the things that I like to remind", "cmZfJpSNh8o-00039-00017416-00017973": "supervisors of is to leave their ego at the door especially new supervisors", "cmZfJpSNh8o-00040-00017973-00018283": "because their honor may be a little bit of a high they've got a little bit of", "cmZfJpSNh8o-00041-00018283-00018763": "power now over the janitors but you want to do that you want to leave that ego at", "cmZfJpSNh8o-00042-00018763-00019165": "the door you want to talk with them on an even level you you know I know", "cmZfJpSNh8o-00043-00019165-00019762": "certain cleaning companies very large cleaning companies that have presidents", "cmZfJpSNh8o-00044-00019762-00020254": "that you know they've they are overseeing thousands of employees yet", "cmZfJpSNh8o-00045-00020254-00020689": "those presidents they go and they talk to their cleaning technicians on a", "cmZfJpSNh8o-00046-00020689-00021109": "regular basis they get down with them and they ask them questions about what's", "cmZfJpSNh8o-00047-00021109-00021475": "going on and they're leaving their ego at the door they're not saying oh I'm", "cmZfJpSNh8o-00048-00021475-00021901": "the president you know they they're in there they honestly want to know how", "cmZfJpSNh8o-00049-00021901-00022281": "their job is going what they can do to make their life easier and that's how it", "cmZfJpSNh8o-00050-00022281-00022792": "should be for every manager in the company you want to make sure that", "cmZfJpSNh8o-00051-00022792-00023085": "you're not asking them to do something that you aren't willing to do yourself", "cmZfJpSNh8o-00052-00023085-00023584": "right if you just always give them the the crummy jobs I mean everybody's gotta", "cmZfJpSNh8o-00053-00023584-00024081": "clean right we know that it's not a clean job who you're cleaning up dirt", "cmZfJpSNh8o-00054-00024081-00024610": "however there are some jobs that nothing likes to do but you know if if you're", "cmZfJpSNh8o-00055-00024610-00024967": "short-handed if you pitch in you show them that you're willing to do whatever", "cmZfJpSNh8o-00056-00024967-00025387": "it takes to get the job done they're gonna respect you more and they're gonna", "cmZfJpSNh8o-00057-00025387-00025839": "want to have your back when they when you need some help right so don't be", "cmZfJpSNh8o-00058-00025839-00026038": "asking them to do something that you aren't willing to do", "cmZfJpSNh8o-00059-00026038-00026719": "yourself when there is a problem make sure that you use it as a training or a", "cmZfJpSNh8o-00060-00026719-00027264": "coaching opportunity don't just be there to reprimand them don't make them feel", "cmZfJpSNh8o-00061-00027264-00027669": "like you're always looking over their shoulder looking for them to make a", "cmZfJpSNh8o-00062-00027669-00028113": "mistake so that you're gonna reprimand them right otherwise they're gonna hate", "cmZfJpSNh8o-00063-00028113-00028558": "seeing you every time you show your face right you want to use these things when", "cmZfJpSNh8o-00064-00028558-00028936": "they make a mistake or you know something happens you want to use it as", "cmZfJpSNh8o-00065-00028936-00029383": "a training opportunity and then while you're doing that make sure you explain", "cmZfJpSNh8o-00066-00029383-00029844": "why you're doing something certain way because if they keep doing it the way", "cmZfJpSNh8o-00067-00029844-00030294": "that they want to do it maybe they don't understand the reason for why we do it", "cmZfJpSNh8o-00068-00030294-00030706": "certain way it's part of it is consistency we want everyone to do", "cmZfJpSNh8o-00069-00030706-00031168": "things at the same way right makes it a lot easier if your mistakes are made", "cmZfJpSNh8o-00070-00031168-00031597": "that way however if you give them the reason behind why something needs to be", "cmZfJpSNh8o-00071-00031597-00032016": "done in a certain way this is so much easier for them to understand oh yeah", "cmZfJpSNh8o-00072-00032016-00032547": "sure I get it I'll do it that way so if you do some of these things you're gonna", "cmZfJpSNh8o-00073-00032547-00033066": "make not only your cleaning technicians happier and feel more respected and", "cmZfJpSNh8o-00074-00033066-00033540": "trusted you're gonna make your own life easier because if when you trust and", "cmZfJpSNh8o-00075-00033540-00034111": "respect and motivate and engage your employees then they're gonna make your", "cmZfJpSNh8o-00076-00034111-00034569": "life so much easier so if you want more tips like this I", "cmZfJpSNh8o-00077-00034569-00034900": "have a whole series on janitorial supervisor training that you can find", "cmZfJpSNh8o-00078-00034900-00035446": "here on YouTube you can subscribe to our Channel and just click on the button on", "cmZfJpSNh8o-00079-00035446-00036043": "the lower right corner and you'll get notified every time we post a new video", "cmZfJpSNh8o-00080-00036043-00036634": "and we also have a complete online video training course on janitorial", "cmZfJpSNh8o-00081-00036634-00037162": "supervision so if you're interested in that I'll have a link below and be sure", "cmZfJpSNh8o-00082-00037162-00037483": "to check that out because it's very comprehensive training just for", "cmZfJpSNh8o-00083-00037483-00037965": "janitorial supervisors thanks and have a great day"}}, {"audio_id": "cnl08psOGMo", "text": {"cnl08psOGMo-00000-00000548-00000953": "the Society of chief librarians and partners are committed to keeping", "cnl08psOGMo-00001-00000955-00001322": "library services accessible and relevant as a strategy", "cnl08psOGMo-00002-00001322-00001691": "for the future a number of universal offers have been developed to cover five", "cnl08psOGMo-00003-00001691-00002183": "key areas of service one of these key areas is learning at West Sussex County", "cnl08psOGMo-00004-00002183-00002542": "Libraries an innovation and development group has been set up to identify", "cnl08psOGMo-00005-00002542-00003071": "promote and to develop our learning offer we have created new web pages", "cnl08psOGMo-00006-00003071-00003604": "dedicated to our learning offer these cover key areas such as languages arts", "cnl08psOGMo-00007-00003604-00004085": "crafts and hobbies local and family history business careers literacy", "cnl08psOGMo-00008-00004085-00004598": "numeracy and qualifications as well as stem and this is the term for science", "cnl08psOGMo-00009-00004598-00005246": "technology engineering and maths the pages can be found by going to the west", "cnl08psOGMo-00010-00005246-00005729": "essex county council website go to libraries additional library services", "cnl08psOGMo-00011-00005729-00006353": "libraries and learning our library learning pages include list of", "cnl08psOGMo-00012-00006353-00006779": "recommended reads thanks to online resources and links to other supporting", "cnl08psOGMo-00013-00006779-00007172": "library pages this helps bring our learning offer together and makes it", "cnl08psOGMo-00014-00007172-00007768": "easier for customers to find in addition to our new web pages we continue to", "cnl08psOGMo-00015-00007768-00008071": "provide new and exciting learning opportunities like stem activities", "cnl08psOGMo-00016-00008071-00008497": "during our geek week campaign and whole family ancestry sessions during our", "cnl08psOGMo-00017-00008497-00008945": "family learning festival also adding new online resources and you regular weekly", "cnl08psOGMo-00018-00008945-00009610": "and monthly activities to our current program to evaluate feedback on the", "cnl08psOGMo-00019-00009610-00010042": "learning offer we've set up an online store of graffiti board this record", "cnl08psOGMo-00020-00010042-00010414": "schedule coins and compliments regarding learning that our staff received on a", "cnl08psOGMo-00021-00010414-00010957": "regular basis from customers this data can be difficult to capture and our", "cnl08psOGMo-00022-00010957-00011389": "graffiti board who help address this by providing somewhere easy and quick to", "cnl08psOGMo-00023-00011389-00011872": "make notes of comments the staff graffiti board can be found on", "cnl08psOGMo-00024-00011872-00012260": "SharePoint on the front page of service management it's designed to be", "cnl08psOGMo-00025-00012260-00012853": "user-friendly just add the library date and staff initials and a brief learning", "cnl08psOGMo-00026-00012853-00013244": "comment from the customer an example can be found at the top of the graffiti", "cnl08psOGMo-00027-00013244-00013900": "board the itg will continue to plan and to develop the learning offer", "cnl08psOGMo-00028-00013900-00014394": "and promote lifelong learning ideas and feedback from all staff are welcome so", "cnl08psOGMo-00029-00014394-00014793": "if you have something to share please get in touch"}}, {"audio_id": "cnCkO9q754I", "text": {"cnCkO9q754I-00001-00000293-00000620": "introduce Koreans don't know Suzuki motorcycle models.", "cnCkO9q754I-00003-00001540-00001850": "This model is called EX7 generic recursion.", "cnCkO9q754I-00004-00001850-00002136": "It was announced at the 2013 Tokyo Motor Show.", "cnCkO9q754I-00006-00002252-00002576": "A 588cc parallel 2-cylinder VGT + intercooler.", "cnCkO9q754I-00007-00002612-00002882": "The maximum output is known as 100 horsepower,", "cnCkO9q754I-00010-00003456-00003730": "The VGT is, for example, a turbo like the VGT on a diesel passenger car trunk badge.", "cnCkO9q754I-00012-00004034-00004284": "VGT Turbo improves the sluggish responsiveness of existing turbochargers.", "cnCkO9q754I-00014-00004562-00004816": "Significantly reduced turbo lags were", "cnCkO9q754I-00015-00004816-00005127": "applied to sporty models that needed", "cnCkO9q754I-00016-00005127-00005417": "immediate response", "cnCkO9q754I-00017-00005417-00005674": "Widely applied,", "cnCkO9q754I-00021-00006442-00006731": "It's been a while, but there have been rumors that a new Hayabusa model will be announced in 2018.", "cnCkO9q754I-00023-00007008-00007292": "At the time, there were rumors of engines that were known to be mounted on the new adverbs.", "cnCkO9q754I-00024-00007292-00007625": "The EX7 engine was mounted on Hayabusa with more than 150 horsepower with 700cc vgt.", "cnCkO9q754I-00027-00008258-00008556": "As time went by in 2019, the rumor was confirmed by other news.", "cnCkO9q754I-00028-00008556-00008844": "The confirmed news is that the new adverbs will be a new four-cylinder 1400cc", "cnCkO9q754I-00029-00008844-00009138": "class and will apply semi-auto missions.", "cnCkO9q754I-00033-00009974-00010726": "Another rumor has it that the new GSX 700T with a parallel two-cylinder engine will be released.", "cnCkO9q754I-00036-00011064-00011245": "We're going to release the aforementioned spec engine", "cnCkO9q754I-00037-00011245-00011348": "as a replacement for the s750.", "cnCkO9q754I-00038-00011348-00011644": "The news is sure to come out.", "cnCkO9q754I-00042-00012292-00012416": "The car was announced at the Tokyo", "cnCkO9q754I-00043-00012416-00012580": "Motor Show in 2005 to celebrate", "cnCkO9q754I-00044-00012580-00012792": "the 25th anniversary of Katana.", "cnCkO9q754I-00047-00013054-00013290": "As it is a commemorative model,", "cnCkO9q754I-00048-00013312-00013738": "the appearance brought a lot of appearance of ED1 ED2.", "cnCkO9q754I-00051-00013838-00014239": "1100cc in 6-cylinder series Maybe 1100cc displacement was used to honor Kanata.", "cnCkO9q754I-00052-00014239-00014504": "Because Suzuki is a brand that likes this hahaha : )", "cnCkO9q754I-00055-00015108-00015410": "It is known to produce about 180 horsepower.", "cnCkO9q754I-00057-00015719-00016047": "LED light features", "cnCkO9q754I-00058-00016094-00016390": "Full color LCD dashboard with Bluetooth + Navigation", "cnCkO9q754I-00061-00016776-00017056": "Semi-automatic mission", "cnCkO9q754I-00063-00017380-00017564": "The singularity is known to be 3 inches narrower than the four-cylinder Hayabusa engine", "cnCkO9q754I-00064-00017564-00017750": "because of the narrow width of each cylinder.", "cnCkO9q754I-00065-00017786-00017930": "Narrow width will not be good for durability.", "cnCkO9q754I-00068-00018290-00018602": "The equipment technology found in the current Suzuki modal model is applied, but it is not new. I could see a preview of the technology.", "cnCkO9q754I-00072-00019312-00019548": "Suzuki's first bike with a Wankel engine.", "cnCkO9q754I-00073-00019548-00019770": "Rare Wankel engine with mass production bike", "cnCkO9q754I-00074-00020784-00021084": "It was produced for two years 1974-1976.", "cnCkO9q754I-00076-00021374-00021658": "The Wankel engine is an initial D engine like the RX7.", "cnCkO9q754I-00077-00021658-00021969": "If the reciprocating engine, the vertical movement of the piston, is a normal engine,", "cnCkO9q754I-00078-00021970-00022298": "The rotary engine is a rotary engine, the rotor is the role of the piston.", "cnCkO9q754I-00079-00022298-00022608": "The cycle is close to two cycles.", "cnCkO9q754I-00080-00022608-00022934": "The characteristics are similar to those of the 2-cycle engine.", "cnCkO9q754I-00081-00022934-00023230": "Have high output at low displacement", "cnCkO9q754I-00082-00023230-00023530": "There is a lot of exhaust gas.", "cnCkO9q754I-00083-00023530-00023816": "Has low fuel efficiency", "cnCkO9q754I-00084-00023816-00023934": "With frequent maintenance cycles", "cnCkO9q754I-00085-00023958-00024254": "For this reason, it seems to have disappeared from the market.", "cnCkO9q754I-00086-00024290-00024408": "Currently, models are easily seen in South America,", "cnCkO9q754I-00087-00024408-00024637": "but most of them do not know whether they exist in Korea.", "cnCkO9q754I-00088-00024638-00025030": "As a successor to gs450, gs500", "cnCkO9q754I-00089-00025030-00025348": "gs500 gs500e gs500f There are three in total.", "cnCkO9q754I-00091-00025980-00026533": "It is a dead bone model produced during 1989-2004.", "cnCkO9q754I-00094-00026832-00027306": "Since 2004-2016, it has been produced in South American plants and sold to Latin America.", "cnCkO9q754I-00097-00027789-00028042": "It has been produced for a relatively long time and is old in many ways", "cnCkO9q754I-00098-00028042-00028334": "So it's cheap but it's fun to run.", "cnCkO9q754I-00100-00028468-00028697": "The difference between GS and GSX is", "cnCkO9q754I-00101-00028698-00028898": "that GS is 2 valves per cylinder, GSX is 4 valves per cylinder.", "cnCkO9q754I-00102-00028898-00029089": "The more valves per cylinder, the higher the output.", "cnCkO9q754I-00108-00030712-00030994": "Yamaha's Genesis engine has five valves per cylinder.", "cnCkO9q754I-00109-00030994-00031044": "487cc  Parallel 2 cylinder 51hp", "cnCkO9q754I-00111-00031272-00031576": "top speed at lest 170km/h", "cnCkO9q754I-00115-00032468-00032749": "I don't know why, but this guy's chassis looks similar to Hyosung's comet250's chassis.", "cnCkO9q754I-00116-00032750-00033058": "Hyosung seems to have referenced it. The truth is only known to Hyosung officials.", "cnCkO9q754I-00119-00033576-00033880": "We have a lot of interesting models that are unknown to us (Korean standard)", "cnCkO9q754I-00120-00033884-00034120": "I will introduce a model that I haven't gotten crazy about next time.", "cnCkO9q754I-00125-00035320-00035670": "Thank you for support."}}, {"audio_id": "cnG6t5EEaOE", "text": {"cnG6t5EEaOE-00000-00000438-00000715": "With social media, we find that you get the best results.", "cnG6t5EEaOE-00001-00000715-00000948": "Not through just posting online.", "cnG6t5EEaOE-00002-00000948-00001208": "But with paid social media advertising.", "cnG6t5EEaOE-00003-00001208-00001344": "You can get so targeted.", "cnG6t5EEaOE-00004-00001344-00001544": "You can find out demographics on people.", "cnG6t5EEaOE-00005-00001544-00001668": "Because through social media.", "cnG6t5EEaOE-00006-00001668-00001867": "You know someone's demographics.", "cnG6t5EEaOE-00007-00001867-00002157": "You can get really targeted with social media marketing.", "cnG6t5EEaOE-00008-00002157-00002294": "And get a great return on the investment.", "cnG6t5EEaOE-00009-00002294-00002449": "For the dollars that you spent."}}, {"audio_id": "dohBBTwhaYc", "text": {"dohBBTwhaYc-00000-00000009-00000350": "Rishiv...Let's do the top 50 billionaires now!", "dohBBTwhaYc-00001-00000360-00000600": "Donald Bren..Donald Bren (dad repeating)", "dohBBTwhaYc-00002-00000610-00000919": "Charles Koch", "dohBBTwhaYc-00003-00000930-00001310": "Leonid Mikhelson", "dohBBTwhaYc-00004-00001310-00001700": "Giovanni Ferrero", "dohBBTwhaYc-00005-00001710-00002100": "Dieter Schwarz", "dohBBTwhaYc-00006-00002110-00002410": "Hui Ka Yan", "dohBBTwhaYc-00007-00002420-00002800": "Michael Dell", "dohBBTwhaYc-00008-00002810-00003140": "David Koch", "dohBBTwhaYc-00009-00003150-00003529": "Sergey Brin", "dohBBTwhaYc-00010-00003543-00003990": "Mark Zuckerberg", "dohBBTwhaYc-00011-00004000-00004550": "Jack Ma..You have to tell loudly...Jack Ma (in cute voice)", "dohBBTwhaYc-00012-00004560-00004891": "Laurene Powell Jobs", "dohBBTwhaYc-00013-00004891-00005300": "Tadashi Yanai", "dohBBTwhaYc-00014-00005300-00005620": "Azim Premji", "dohBBTwhaYc-00015-00005630-00005966": "Susanne Klatten", "dohBBTwhaYc-00016-00005966-00006200": "Pony Ma", "dohBBTwhaYc-00017-00006210-00006581": "Lee Shau Kee", "dohBBTwhaYc-00018-00006581-00006940": "Phil Knight", "dohBBTwhaYc-00019-00006950-00007308": "Rob Walton", "dohBBTwhaYc-00020-00007308-00007700": "Larry Ellison", "dohBBTwhaYc-00021-00007709-00008030": "Len Blavatnik", "dohBBTwhaYc-00022-00008040-00008530": "Rupert Murdoch", "dohBBTwhaYc-00023-00008540-00009440": "Tata Group...What is the name of this guy? Pallonji Mistry", "dohBBTwhaYc-00024-00009450-00009720": "Bill Gates", "dohBBTwhaYc-00025-00009720-00010010": "Jacqueline Mars", "dohBBTwhaYc-00026-00010020-00010600": "Steve Ballmer", "dohBBTwhaYc-00027-00010600-00011270": "What is the name of this guy? Sheldon Adelson", "dohBBTwhaYc-00028-00011270-00011700": "Goerge Lemann", "dohBBTwhaYc-00029-00011700-00012470": "Jeff Bezos...Jeff Bezos is Number 1 in the WORLD!", "dohBBTwhaYc-00030-00012480-00012900": "John Mars", "dohBBTwhaYc-00031-00012900-00013319": "Vladimir Lisin", "dohBBTwhaYc-00032-00013319-00013719": "Alexey Mordashov", "dohBBTwhaYc-00033-00013730-00014100": "Bernard Arnault", "dohBBTwhaYc-00034-00014100-00014446": "Carlos Slim", "dohBBTwhaYc-00035-00014446-00014800": "Jim Walton", "dohBBTwhaYc-00036-00014810-00015191": "Carl Icahn", "dohBBTwhaYc-00037-00015191-00015519": "Larry Page", "dohBBTwhaYc-00038-00015519-00015738": "Li Ka Shing", "dohBBTwhaYc-00039-00015738-00016100": "Mukesh Ambani (He is asking for this card)..(Dad saying) it will come", "dohBBTwhaYc-00040-00016100-00016510": "Alain Wertheimer", "dohBBTwhaYc-00041-00016520-00017110": "Amancio Ortega. You have to tell loudly. Amancio Ortega", "dohBBTwhaYc-00042-00017120-00017480": "Michael Bloomberg", "dohBBTwhaYc-00043-00017490-00017860": "Vladimir Potanin", "dohBBTwhaYc-00044-00017860-00018300": "Mukesh Ambani", "dohBBTwhaYc-00045-00018300-00018740": "Elon Musk..who is this? Elon Musk", "dohBBTwhaYc-00046-00018750-00019150": "Alice Walton", "dohBBTwhaYc-00047-00019150-00019500": "Francoise Meyers", "dohBBTwhaYc-00048-00019500-00019850": "Warren Buffet", "dohBBTwhaYc-00049-00019850-00020240": "Gerard Wertheimer", "dohBBTwhaYc-00050-00020250-00020590": "Francois Pinault", "dohBBTwhaYc-00051-00020600-00020950": "Leonardo Del Vecchio", "dohBBTwhaYc-00052-00020960-00021290": "Clap!Clap!Clap!"}}, {"audio_id": "dotA3wGqCjM", "text": {"dotA3wGqCjM-00000-00002918-00003158": "- Alright, looks like we're live.", "dotA3wGqCjM-00001-00003158-00003554": "So thank you all for joining us this morning.", "dotA3wGqCjM-00002-00003554-00004054": "I have Peleg Hadar and Tomer Bar who are gonna be here", "dotA3wGqCjM-00003-00004090-00004362": "to be talking about their research", "dotA3wGqCjM-00004-00004362-00004787": "into their Stuxnet printing vulnerabilities that they found", "dotA3wGqCjM-00005-00004787-00005135": "that are still around after 10 years later.", "dotA3wGqCjM-00006-00005135-00005553": "But to start things off, we have two first-time speakers", "dotA3wGqCjM-00007-00005553-00005950": "and as our tradition in DEF CON, we shot the newbies.", "dotA3wGqCjM-00008-00005950-00006235": "And so I'd like to invite you all", "dotA3wGqCjM-00009-00006235-00006427": "to join me in the chat folks.", "dotA3wGqCjM-00010-00006427-00006573": "Here's to your talk.", "dotA3wGqCjM-00011-00006809-00006893": "- Thank you.", "dotA3wGqCjM-00012-00006893-00006976": "- Cheers.", "dotA3wGqCjM-00013-00007259-00007427": "- Alright, great.", "dotA3wGqCjM-00014-00007427-00007705": "So we actually have our first question on the line", "dotA3wGqCjM-00015-00007794-00008022": "and said, can you please explain more", "dotA3wGqCjM-00016-00008022-00008241": "about the fuzzing process when finding corruption", "dotA3wGqCjM-00017-00008241-00008472": "in the SHD files?", "dotA3wGqCjM-00018-00008715-00008798": "- Yeah, sure.", "dotA3wGqCjM-00019-00008892-00009045": "So actually it was really interesting because", "dotA3wGqCjM-00020-00009045-00009453": "we didn't want to use some, I dunno,", "dotA3wGqCjM-00021-00009453-00009700": "were already existing tool.", "dotA3wGqCjM-00022-00009700-00009940": "We wanted to do something on our own.", "dotA3wGqCjM-00023-00009940-00010320": "So after we understood the SHD processing", "dotA3wGqCjM-00024-00010780-00011065": "and all of this stuff, we just wanted to do", "dotA3wGqCjM-00025-00011065-00011246": "the most naive thing.", "dotA3wGqCjM-00026-00011246-00011477": "We just written our own by phone script,", "dotA3wGqCjM-00027-00011477-00011935": "which takes already existing SHD file which works.", "dotA3wGqCjM-00028-00012203-00012670": "And we just mutated it one by one in one bite at a time.", "dotA3wGqCjM-00029-00012670-00013024": "And we use zero to FF on each bite", "dotA3wGqCjM-00030-00013024-00013205": "and we didn't do anything that,", "dotA3wGqCjM-00031-00013205-00013624": "it was dependent by each bite.", "dotA3wGqCjM-00032-00013624-00013958": "We just did it, each bite at a time.", "dotA3wGqCjM-00033-00014113-00014421": "Afterwards, we just dropped all the SHD files", "dotA3wGqCjM-00034-00014421-00014638": "and we wanted to make sure it's working.", "dotA3wGqCjM-00035-00014638-00014894": "And we understood that there's some kind of a limit", "dotA3wGqCjM-00036-00014978-00015132": "in the service that it won't process", "dotA3wGqCjM-00037-00015132-00015394": "more than 256 files at a time.", "dotA3wGqCjM-00038-00015394-00015708": "So we just modified the spooler service.", "dotA3wGqCjM-00039-00015708-00015955": "We just patch it and we replace", "dotA3wGqCjM-00040-00015955-00016181": "the check with knobs, of course.", "dotA3wGqCjM-00041-00016181-00016490": "And then we just, carry on, a kind of a spooler", "dotA3wGqCjM-00042-00016490-00016723": "which was modified and it just work.", "dotA3wGqCjM-00043-00016819-00016909": "Then it took 20 minutes,", "dotA3wGqCjM-00044-00016909-00017237": "it processed all the SHD files then it rest.", "dotA3wGqCjM-00045-00017237-00017526": "So it was critical.", "dotA3wGqCjM-00046-00017526-00017884": "We don't intend to release the Python script", "dotA3wGqCjM-00047-00017884-00018209": "but maybe we will, we need to discuss it.", "dotA3wGqCjM-00048-00018394-00018477": "- Very cool, yeah.", "dotA3wGqCjM-00049-00018477-00018970": "I was pretty impressed with the ability of what you guys did", "dotA3wGqCjM-00050-00019175-00019370": "and sort of walking through the entire,", "dotA3wGqCjM-00051-00019585-00019870": "for lack of a better term, kill-chain of the Stuxnet.", "dotA3wGqCjM-00052-00019963-00020304": "I mean, how much of studying that original code", "dotA3wGqCjM-00053-00020405-00020633": "do you think influenced your discovery", "dotA3wGqCjM-00054-00020633-00021025": "of these remaining, these malign vulnerabilities?", "dotA3wGqCjM-00055-00021152-00021499": "- Yeah, I think it was pretty much because", "dotA3wGqCjM-00056-00021499-00021861": "when we started to look at it, we thought that, okay,", "dotA3wGqCjM-00057-00021861-00022097": "it's 10 years of the Stuxnet,", "dotA3wGqCjM-00058-00022097-00022511": "a lot of very strong researchers already research it.", "dotA3wGqCjM-00059-00022511-00022910": "What are the chances that we will find anything new?", "dotA3wGqCjM-00060-00022910-00023215": "But we came with a lot of motivation", "dotA3wGqCjM-00061-00023215-00023715": "and after seeing that the first patch was not fully patched", "dotA3wGqCjM-00062-00023767-00023993": "and can be re-exploited and the second patch", "dotA3wGqCjM-00063-00023993-00024266": "and the third patch, so we understood", "dotA3wGqCjM-00064-00024266-00024637": "that we are onto something and other the research", "dotA3wGqCjM-00065-00024637-00024789": "and after 20 minutes of fuzzing,", "dotA3wGqCjM-00066-00024789-00025220": "you get your first crash and it's not usual.", "dotA3wGqCjM-00067-00025220-00025608": "And that gave us a hope that we'll find more.", "dotA3wGqCjM-00068-00025751-00025939": "And yeah, it's happened.", "dotA3wGqCjM-00069-00026386-00026642": "- Great, we have another question from the audience,", "dotA3wGqCjM-00070-00026642-00026967": "who said was the SHD crash exploitable?", "dotA3wGqCjM-00071-00027071-00027259": "Plea, good question.", "dotA3wGqCjM-00072-00027259-00027591": "From what we, you've seen it wasn't exploitable.", "dotA3wGqCjM-00073-00027591-00027853": "It was only one bite which was controllable", "dotA3wGqCjM-00074-00027853-00028247": "and it was pretty odd.", "dotA3wGqCjM-00075-00028247-00028512": "I mean, we're pretty sorry it wasn't exploitable", "dotA3wGqCjM-00076-00028512-00028882": "but we really invite everyone to try and maybe", "dotA3wGqCjM-00077-00028882-00029079": "to understand whether it's exploitable or not.", "dotA3wGqCjM-00078-00029079-00029314": "And if it did, if it's exploitable,", "dotA3wGqCjM-00079-00029314-00029575": "so tweet about it and you can mention me", "dotA3wGqCjM-00080-00029575-00029854": "and it'll be with me, it will be a very interesting", "dotA3wGqCjM-00081-00029854-00030183": "because as we mentioned, the Microsoft, it didn't fix it,", "dotA3wGqCjM-00082-00030183-00030327": "so it might be more interesting", "dotA3wGqCjM-00083-00030327-00030526": "and maybe if you'll find something,", "dotA3wGqCjM-00084-00030526-00030766": "you can report it to Microsoft as well.", "dotA3wGqCjM-00085-00030766-00030873": "So good luck.", "dotA3wGqCjM-00086-00031220-00031473": "- Actually, we see a lot of people and a lot of researchers", "dotA3wGqCjM-00087-00031473-00031832": "that haven't been in the spooler", "dotA3wGqCjM-00088-00031832-00032204": "and now we see a lot of research on the spooler.", "dotA3wGqCjM-00089-00032204-00032479": "We hope we'll contribute to that.", "dotA3wGqCjM-00090-00032573-00032656": "- Definitely.", "dotA3wGqCjM-00091-00033078-00033313": "Oh, is there another question?", "dotA3wGqCjM-00092-00033313-00033779": "- Yeah, so the other vowels were they found", "dotA3wGqCjM-00093-00033779-00033914": "by fuzzing or code review?", "dotA3wGqCjM-00094-00034088-00034277": "- So, actually good question.", "dotA3wGqCjM-00095-00034277-00034745": "So after we started fuzzing and we had our first crash,", "dotA3wGqCjM-00096-00034745-00035065": "we were intrigued enough in order to move", "dotA3wGqCjM-00097-00035065-00035317": "to the manual source called auditing", "dotA3wGqCjM-00098-00035317-00035492": "and manual binary auditing.", "dotA3wGqCjM-00099-00035492-00035924": "So it was fine completely manually, 100%.", "dotA3wGqCjM-00100-00035924-00036296": "We just looked at the code and we understood", "dotA3wGqCjM-00101-00036296-00036709": "how the mechanism works and what kind of use cases we can", "dotA3wGqCjM-00102-00036709-00037038": "challenge the mechanism and we just found it manually,", "dotA3wGqCjM-00103-00037038-00037211": "where it was critical.", "dotA3wGqCjM-00104-00037403-00037903": "Basically, we're, we, I know, I do, I think Tomer as well,", "dotA3wGqCjM-00105-00037903-00038128": "we use less fuzzing, we generally,", "dotA3wGqCjM-00106-00038128-00038324": "we do more manual code auditing", "dotA3wGqCjM-00107-00038435-00038737": "but I think you can find interesting bugs", "dotA3wGqCjM-00108-00038856-00039198": "using fuzzing and using manual code auditing", "dotA3wGqCjM-00109-00039326-00039644": "if you use both, which will be probably the best.", "dotA3wGqCjM-00110-00040084-00040317": "- Yeah, so you mentioned the Microsoft decision", "dotA3wGqCjM-00111-00040317-00040630": "not to patch that, I was actually wondering I mean,", "dotA3wGqCjM-00112-00040630-00041079": "do you think that they were justified in their logic on that", "dotA3wGqCjM-00113-00041079-00041314": "or would you have liked to see it in a patched?", "dotA3wGqCjM-00114-00041625-00042076": "- Well, I think that they have a very clear", "dotA3wGqCjM-00115-00042272-00042691": "security boundary and a service material on MSRC.", "dotA3wGqCjM-00116-00042691-00042966": "I don't wanna say whether I think it's right or not", "dotA3wGqCjM-00117-00042966-00043305": "but all I can say is that they mentioned that", "dotA3wGqCjM-00118-00043305-00043794": "local deny of services is not, it's not faster", "dotA3wGqCjM-00119-00043794-00044062": "as the service material and therefore it won't be fixed.", "dotA3wGqCjM-00120-00044062-00044300": "Maybe they will decide to fix it,", "dotA3wGqCjM-00121-00044300-00044550": "if it will be used in order to abuse or something", "dotA3wGqCjM-00122-00044550-00044888": "but I respect their decision.", "dotA3wGqCjM-00123-00044888-00044971": "- All right.", "dotA3wGqCjM-00124-00044971-00045252": "- Yeah, totally agree and maybe other vendors,", "dotA3wGqCjM-00125-00045252-00045554": "any other vendors will see a significance for that", "dotA3wGqCjM-00126-00045554-00045771": "and maybe the anti-virus for other security", "dotA3wGqCjM-00127-00045771-00046232": "for both can manage to prevent this exploit.", "dotA3wGqCjM-00128-00046535-00046726": "- And so you mentioned the, oh ahead.", "dotA3wGqCjM-00129-00046726-00046852": "- Oh, I have a question.", "dotA3wGqCjM-00130-00046852-00046977": "So when I was watching the video,", "dotA3wGqCjM-00131-00046977-00047352": "I noticed that when it came to the last path vulnerability,", "dotA3wGqCjM-00132-00047352-00047510": "you can kind of give a very pregnant,", "dotA3wGqCjM-00133-00047510-00047752": "there is no vulnerability yet.", "dotA3wGqCjM-00134-00047752-00047956": "And is that more because you guys are expecting", "dotA3wGqCjM-00135-00047956-00048206": "one to come out or have a theory that there is one out", "dotA3wGqCjM-00136-00048206-00048375": "that just hasn't been released in a while?", "dotA3wGqCjM-00137-00048375-00048747": "Like there was a big emphasis on that. (laughs)", "dotA3wGqCjM-00138-00048853-00049056": "- We don't have anything up in our sleeve", "dotA3wGqCjM-00139-00049056-00049304": "and we don't know about anything and of course,", "dotA3wGqCjM-00140-00049304-00049637": "if we will know, we will report it to Microsoft.", "dotA3wGqCjM-00141-00049637-00050137": "But all we said is, you have two paths which were exploited", "dotA3wGqCjM-00142-00050201-00050571": "and you have the third one which might be exploited", "dotA3wGqCjM-00143-00050571-00050869": "imagine that, we don't know about anything that, yeah,", "dotA3wGqCjM-00144-00050869-00051308": "we know as much as you know but I don't know.", "dotA3wGqCjM-00145-00051308-00051747": "Maybe we will find that Microsoft Patsy in the future", "dotA3wGqCjM-00146-00051866-00051990": "but nothing concrete.", "dotA3wGqCjM-00147-00052874-00053185": "- Right, so we actually have another question on the line.", "dotA3wGqCjM-00148-00053185-00053366": "So after your experience on this,", "dotA3wGqCjM-00149-00053366-00053494": "what would you say to researchers attempting", "dotA3wGqCjM-00150-00053494-00053820": "to replicate the same vulnerabilities on siemens", "dotA3wGqCjM-00151-00053820-00054045": "microcontrollers matching those in Iran?", "dotA3wGqCjM-00152-00054574-00054911": "- So Tomer, do you wanna take it?", "dotA3wGqCjM-00153-00054911-00055411": "- See if he can repeat the questions so I can understand.", "dotA3wGqCjM-00154-00055441-00055692": "- Yeah, I said after your experience", "dotA3wGqCjM-00155-00055692-00055866": "Sir, what would you say to researchers attempting", "dotA3wGqCjM-00156-00055866-00056180": "to replicate the same vulnerabilities on siemens", "dotA3wGqCjM-00157-00056180-00056449": "microcontrollers matching those in Iran?", "dotA3wGqCjM-00158-00056632-00056991": "- Well, actually this is not the focus of our research,", "dotA3wGqCjM-00159-00056991-00057256": "so we are not expert on that.", "dotA3wGqCjM-00160-00057256-00057637": "I think that our research is basically focused", "dotA3wGqCjM-00161-00057637-00058029": "on the propagation part of a subset and the spooler service", "dotA3wGqCjM-00162-00058029-00058392": "and specifically, the spooler services on the windows,", "dotA3wGqCjM-00163-00058513-00059013": "Microsoft cons, so it's not related to the hardware", "dotA3wGqCjM-00164-00059074-00059509": "or anything else, just any different windows OS album.", "dotA3wGqCjM-00165-00059876-00060369": "- Yeah, definitely I think it's a huge domain Stuxnet", "dotA3wGqCjM-00166-00060369-00060671": "and we have so many aspects to book.", "dotA3wGqCjM-00167-00060671-00060971": "We focus on the windows part.", "dotA3wGqCjM-00168-00061062-00061408": "We don't know if the fact that we found a vulnerability", "dotA3wGqCjM-00169-00061408-00061908": "in the same domain in the window spot, we'll, just said that", "dotA3wGqCjM-00170-00062045-00062307": "if you'll do the same in the Siemens PLC will be the same", "dotA3wGqCjM-00171-00062307-00062793": "but I think it is interesting word", "dotA3wGqCjM-00172-00062793-00063005": "that if you want to get into,", "dotA3wGqCjM-00173-00063005-00063177": "just share it with the community,", "dotA3wGqCjM-00174-00063177-00063319": "I think it will be interesting enough", "dotA3wGqCjM-00175-00063319-00063552": "to people to come and see.", "dotA3wGqCjM-00176-00063552-00063771": "So maybe we'll see you in that one next week", "dotA3wGqCjM-00177-00063771-00063891": "answering this question.", "dotA3wGqCjM-00178-00064012-00064167": "- Yeah, if somebody tells me if they actually have", "dotA3wGqCjM-00179-00064167-00064396": "anyone has an O day up their sleeve", "dotA3wGqCjM-00180-00064396-00064587": "for a Siemens Microcontrollers, they're probably", "dotA3wGqCjM-00181-00064587-00065087": "not presenting that at DEF CON but we'll see. (laughs)", "dotA3wGqCjM-00182-00065305-00065805": "Right, so you talked about the spooler", "dotA3wGqCjM-00183-00066109-00066407": "or you demonstrated how the spooler was exploited", "dotA3wGqCjM-00184-00066407-00066714": "by a local user to get the escalation.", "dotA3wGqCjM-00185-00066858-00067105": "It seemed like you were hinting that this might still be", "dotA3wGqCjM-00186-00067105-00067451": "a remote capability as well, did you find that or not?", "dotA3wGqCjM-00187-00067572-00067933": "- No, actually we were only focused on the local,", "dotA3wGqCjM-00188-00067933-00068267": "local improved installation, advertar", "dotA3wGqCjM-00189-00068267-00068611": "and we haven't found a way to bypass the patch,", "dotA3wGqCjM-00190-00068611-00069111": "the original patch to get them more good execution.", "dotA3wGqCjM-00191-00069438-00069678": "- Right, so it looks like we've got another question", "dotA3wGqCjM-00192-00069678-00069853": "coming in but so", "dotA3wGqCjM-00193-00070380-00070548": "we were waiting for typing to be done.", "dotA3wGqCjM-00194-00070548-00070812": "But, so earlier you talked about", "dotA3wGqCjM-00195-00071233-00071706": "walking through Stuxnet process and sort of finding,", "dotA3wGqCjM-00196-00071830-00072102": "which vulnerability is still existed.", "dotA3wGqCjM-00197-00072102-00072376": "So your original intent was to recreate that", "dotA3wGqCjM-00198-00072376-00072648": "and look for residual or was it to actually", "dotA3wGqCjM-00199-00072648-00073130": "to look at what vulnerabilities that by themselves", "dotA3wGqCjM-00200-00073130-00073263": "maybe still available?", "dotA3wGqCjM-00201-00073415-00073791": "- So, yeah, the first question was if we,", "dotA3wGqCjM-00202-00073884-00074004": "in building Stuxnet, people were in doubt", "dotA3wGqCjM-00203-00074004-00074268": "of the patch up by force legendary.", "dotA3wGqCjM-00204-00074463-00074963": "When we start to look at the components and we saw that", "dotA3wGqCjM-00205-00074980-00075480": "if for a fall, our lack, of community lack of the discovery,", "dotA3wGqCjM-00206-00075768-00076024": "the equivalent vulnerabilities that were found", "dotA3wGqCjM-00207-00076024-00076275": "in the last decade, we were legendary built the Stuxnet", "dotA3wGqCjM-00208-00076275-00076583": "to a point of, where the stores to Microsoft", "dotA3wGqCjM-00209-00076583-00076707": "in a safe manner.", "dotA3wGqCjM-00210-00076798-00077298": "But if evil corp that will manage to do it by themselves", "dotA3wGqCjM-00211-00077389-00077730": "single (murmurs) and it allegedly", "dotA3wGqCjM-00212-00077730-00078079": "could build equivalent capabilities", "dotA3wGqCjM-00213-00078079-00078273": "of probation capabilities of Stuxnet.", "dotA3wGqCjM-00214-00078273-00078605": "So we ask ourselves, okay, what else is missing?", "dotA3wGqCjM-00215-00078605-00078753": "And the only missing part was", "dotA3wGqCjM-00216-00078753-00078977": "the printer spooler of morbidity.", "dotA3wGqCjM-00217-00078977-00079323": "So before it would be a very interesting research", "dotA3wGqCjM-00218-00079323-00079637": "and it was, so we started to dig in", "dotA3wGqCjM-00219-00079637-00079990": "and follow the three morbidities, yeah.", "dotA3wGqCjM-00220-00080270-00080539": "- Next question we have in chat is what do you think", "dotA3wGqCjM-00221-00080539-00081039": "about the state of variant analysis in the windows platform?", "dotA3wGqCjM-00222-00081245-00081583": "- What do you mean by variant analysis?", "dotA3wGqCjM-00223-00081583-00081704": "- We'll have a follow up there - Yeah.", "dotA3wGqCjM-00224-00081704-00081888": "- And then I'll get back first.", "dotA3wGqCjM-00225-00082040-00082312": "Alright, so the next one was,", "dotA3wGqCjM-00226-00082312-00082569": "were there any unused methods found by you", "dotA3wGqCjM-00227-00082569-00082909": "in Stuxnet code revealing any possible plan", "dotA3wGqCjM-00228-00082909-00083059": "for future attack?", "dotA3wGqCjM-00229-00083218-00083687": "- No, actually we haven't solved that matrix.", "dotA3wGqCjM-00230-00083687-00083886": "- Yeah, we didn't mean, I mean,", "dotA3wGqCjM-00231-00083886-00084215": "we didn't look on Stuxnet code or we just,", "dotA3wGqCjM-00232-00084309-00084472": "we were focused on different vulnerability", "dotA3wGqCjM-00233-00084472-00084686": "to introduce the Stuxnet we didn't", "dotA3wGqCjM-00234-00084686-00084795": "and the propagation parts,", "dotA3wGqCjM-00235-00084795-00085139": "we didn't dive in into Stuxnet code.", "dotA3wGqCjM-00236-00085456-00085666": "- Clarification on that last question,", "dotA3wGqCjM-00237-00085666-00085824": "when it comes to variant analysis,", "dotA3wGqCjM-00238-00085824-00086117": "they were speaking to like analysis existing", "dotA3wGqCjM-00239-00086117-00086336": "vulnerabilities to find variance.", "dotA3wGqCjM-00240-00086430-00086793": "- Okay, I think if I got it correctly,", "dotA3wGqCjM-00241-00086793-00087088": "I think that the safe, I mean,", "dotA3wGqCjM-00242-00087088-00087520": "it's very interesting because I know that once someone find", "dotA3wGqCjM-00243-00087626-00087986": "a pretty common backlash, a lot of other researchers", "dotA3wGqCjM-00244-00087986-00088235": "are diving into it and find a lot, I mean,", "dotA3wGqCjM-00245-00088235-00088701": "if you can take a look of MSRC each month,", "dotA3wGqCjM-00246-00088701-00089018": "they're obviously releasing their bulletin of best using.", "dotA3wGqCjM-00247-00089111-00089421": "I think that the very common vulnerability", "dotA3wGqCjM-00248-00089421-00089636": "backlash is of course the elevation of privilege,", "dotA3wGqCjM-00249-00089636-00089989": "which is caused by a logic bugs.", "dotA3wGqCjM-00250-00089989-00090188": "And I think that you can see a lot.", "dotA3wGqCjM-00251-00090188-00090446": "And I think that the trend got started,", "dotA3wGqCjM-00252-00090446-00090629": "I don't know if officially but at least", "dotA3wGqCjM-00253-00090629-00090780": "what I know is James Forshaw,", "dotA3wGqCjM-00254-00090920-00091420": "just took a look of all the file system privileged issues", "dotA3wGqCjM-00255-00091555-00091982": "and released a lot of tools that help other researchers", "dotA3wGqCjM-00256-00091982-00092133": "to take a look of it and then people", "dotA3wGqCjM-00257-00092133-00092445": "just found a lot of variance.", "dotA3wGqCjM-00258-00092612-00093056": "So I think that is definitely pretty discussed", "dotA3wGqCjM-00259-00093056-00093556": "the topic and I know that I will keep", "dotA3wGqCjM-00260-00093658-00093781": "and take a look history backwards", "dotA3wGqCjM-00261-00093781-00094048": "still exists if that answered your question.", "dotA3wGqCjM-00262-00094158-00094544": "- Yeah and if I may add, that's why we started", "dotA3wGqCjM-00263-00094765-00095123": "to develop our Libre, mitigation libre", "dotA3wGqCjM-00264-00095123-00095424": "that is not focused on specific variant,", "dotA3wGqCjM-00265-00095424-00095798": "source of the root cause of the entire (mumbles)", "dotA3wGqCjM-00266-00096038-00096538": "So I believe that if there will be a future exploit", "dotA3wGqCjM-00267-00096856-00097092": "in this backlash and this Libre,", "dotA3wGqCjM-00268-00097092-00097304": "which is (mumbles) and see if someone will take it", "dotA3wGqCjM-00269-00097304-00097735": "and make it more product ready, production ready.", "dotA3wGqCjM-00270-00097735-00098040": "So may, get some new future experts.", "dotA3wGqCjM-00271-00098729-00098892": "- Yeah, definitely.", "dotA3wGqCjM-00272-00098892-00099268": "I think it will be interesting to see if any vendor adopting", "dotA3wGqCjM-00273-00099268-00099743": "the data here implemented in there, in his own net product.", "dotA3wGqCjM-00274-00099842-00099985": "- Yeah, I'm glad you mentioned the driver.", "dotA3wGqCjM-00275-00099985-00100485": "I was pretty impressed with your publication of that", "dotA3wGqCjM-00276-00100509-00100934": "and the analysis of those universal right, new locations.", "dotA3wGqCjM-00277-00101183-00101548": "I mean, it seems like that's something that could be fixed", "dotA3wGqCjM-00278-00101548-00101801": "in policy as well, do you see, what do you see", "dotA3wGqCjM-00279-00101801-00102025": "the advantage of using the driver approach", "dotA3wGqCjM-00280-00102025-00102388": "you did over a just an ACO or a policy or something?", "dotA3wGqCjM-00281-00102527-00102892": "- I mean, it can be fixed by policy, you right.", "dotA3wGqCjM-00282-00102981-00103428": "I mean, we want it to demonstrate the solution.", "dotA3wGqCjM-00283-00103428-00103871": "It's not like we're saying that it's 100% sealed", "dotA3wGqCjM-00284-00103979-00104250": "and there are no nobody's it's obtained by passing", "dotA3wGqCjM-00285-00104250-00104401": "how do we think it wasn't pretty,", "dotA3wGqCjM-00286-00104401-00104597": "good way to demonstrate it?", "dotA3wGqCjM-00287-00104597-00105030": "I think that the use of a minified to driver is good", "dotA3wGqCjM-00288-00105117-00105502": "because obviously you catch the IRPs and the IO requests", "dotA3wGqCjM-00289-00105502-00105777": "pretty low and you can just block it and cancel it.", "dotA3wGqCjM-00290-00105881-00106207": "I don't know where, what kind of a white listing", "dotA3wGqCjM-00291-00106424-00106735": "or you know where policy, you will use obviously,", "dotA3wGqCjM-00292-00106735-00107013": "the vendor can just implement it by using his own", "dotA3wGqCjM-00293-00107013-00107251": "MiniCam driver Minified driver", "dotA3wGqCjM-00294-00107251-00107619": "but I think it's a pretty good demonstration.", "dotA3wGqCjM-00295-00107755-00107839": "- All right.", "dotA3wGqCjM-00296-00108076-00108319": "So we talked about this a little before the code started.", "dotA3wGqCjM-00297-00108433-00108783": "I think the most comical thing I saw in your presentation", "dotA3wGqCjM-00298-00108783-00109038": "was that you all managed somehow", "dotA3wGqCjM-00299-00109038-00109352": "to get the lead tag on your CVE.", "dotA3wGqCjM-00300-00109443-00109760": "Was that something that you actually timed", "dotA3wGqCjM-00301-00109760-00110155": "or was it just a happy coincidence that Microsoft", "dotA3wGqCjM-00302-00110155-00110655": "labeled you guys lead with their CVE-2021-337?", "dotA3wGqCjM-00303-00110733-00110833": "- It wasn't happy coincidence,", "dotA3wGqCjM-00304-00110833-00111046": "it was the happiest coincidence.", "dotA3wGqCjM-00305-00111046-00111329": "I mean, we didn't organize anything.", "dotA3wGqCjM-00306-00111329-00111619": "We didn't ask for it, we just got it there.", "dotA3wGqCjM-00307-00111619-00111960": "Thank you for a Nate work fields from MSRC.", "dotA3wGqCjM-00308-00112047-00112442": "We signed it, it's an awesome CV number.", "dotA3wGqCjM-00309-00112442-00112774": "And I think everyone wanted to get it, so aware.", "dotA3wGqCjM-00310-00112972-00113289": "Maybe next year, one more time.(laughs)", "dotA3wGqCjM-00311-00113540-00113827": "- I think I have all the big word of questions.", "dotA3wGqCjM-00312-00113827-00113949": "On this, I'm gonna throw this one out", "dotA3wGqCjM-00313-00113949-00114132": "even after the other one.", "dotA3wGqCjM-00314-00114132-00114333": "In you're talking, you focused a bit about", "dotA3wGqCjM-00315-00114333-00114616": "how the last patch, the previous patch had kind", "dotA3wGqCjM-00316-00114616-00114832": "of filled the concept of remote execution", "dotA3wGqCjM-00317-00114832-00115043": "and all of these were focused on local", "dotA3wGqCjM-00318-00115043-00115303": "with these new releases that you've just done", "dotA3wGqCjM-00319-00115303-00115412": "as a POC releases, what do you think", "dotA3wGqCjM-00320-00115412-00115656": "that there's a chance that this is kind", "dotA3wGqCjM-00321-00115656-00115886": "of fixed into remote execution now?", "dotA3wGqCjM-00322-00116121-00116460": "- It's not likely but we'll see.", "dotA3wGqCjM-00323-00116764-00116847": "- Yeah.", "dotA3wGqCjM-00324-00117319-00117644": "- Yeah, I warned you guys against one-word answers", "dotA3wGqCjM-00325-00117644-00117976": "but we'll let you slide on that one too.", "dotA3wGqCjM-00326-00117976-00118153": "- I feel like I just put a very pregnant question", "dotA3wGqCjM-00327-00118153-00118442": "out there, it's like, come on guys. (laughs)", "dotA3wGqCjM-00328-00118750-00118999": "- Now we're pretty happy to have you guys.", "dotA3wGqCjM-00329-00118999-00119278": "I think this was pretty, pretty interesting.", "dotA3wGqCjM-00330-00119278-00119485": "I think there was a really, I really appreciated", "dotA3wGqCjM-00331-00119485-00119943": "the sort of a complete walkthrough of the,", "dotA3wGqCjM-00332-00119943-00120443": "what the malware did and what exploited each way, each step.", "dotA3wGqCjM-00333-00120784-00121101": "And I think, like you said, this may have been", "dotA3wGqCjM-00334-00121101-00121293": "or there should have been something that was covered", "dotA3wGqCjM-00335-00121293-00121468": "pretty extensively over the last 10 years", "dotA3wGqCjM-00336-00121468-00121864": "but going back and revisiting those", "dotA3wGqCjM-00337-00121864-00122122": "can have happy coincidence as well, right?", "dotA3wGqCjM-00338-00122419-00122602": "- Yeah, definitely.", "dotA3wGqCjM-00339-00122602-00122924": "I think that they'll be glad to see another", "dotA3wGqCjM-00340-00123052-00123318": "briefing and walkthrough in a decade.", "dotA3wGqCjM-00341-00123318-00123677": "So it feels someone will remember.", "dotA3wGqCjM-00342-00123677-00124100": "It will be probably still interesting to see.", "dotA3wGqCjM-00343-00124100-00124301": "- The next time on the Vegas.", "dotA3wGqCjM-00344-00124301-00124622": "- Yeah, definitely. (laughs)", "dotA3wGqCjM-00345-00124961-00125252": "- Okay, so we're coming up on only 10 minutes left.", "dotA3wGqCjM-00346-00125252-00125397": "Do you guys have any last words", "dotA3wGqCjM-00347-00125397-00125563": "you'd like to share about the research?", "dotA3wGqCjM-00348-00125563-00125861": "I shared your GitHub out there", "dotA3wGqCjM-00349-00125861-00126160": "and I understand that you've kind of got one more", "dotA3wGqCjM-00350-00126247-00126608": "release up your sleeves waiting for patch Tuesday next week.", "dotA3wGqCjM-00351-00126753-00127067": "Do you wanna give us a preview of what we may see them?", "dotA3wGqCjM-00352-00127067-00127368": "- Yeah, so actually we gave it the preview during our talk.", "dotA3wGqCjM-00353-00127368-00127779": "We had a video which demonstrated the demo", "dotA3wGqCjM-00354-00127779-00128229": "of how we bypassed the pets of CV-2020- 1048", "dotA3wGqCjM-00355-00128229-00128373": "and how we exploited it.", "dotA3wGqCjM-00356-00128373-00128550": "Obviously we can provide the details now", "dotA3wGqCjM-00357-00128550-00128832": "but we will have to wait till the last moment", "dotA3wGqCjM-00358-00128980-00129129": "when the best will be released.", "dotA3wGqCjM-00359-00129129-00129540": "We hope it will be on the following best Tuesday.", "dotA3wGqCjM-00360-00129540-00129783": "That's what MSRC told us but we can't guarantee it", "dotA3wGqCjM-00361-00129783-00129960": "of course, because we're not Microsoft.", "dotA3wGqCjM-00362-00129960-00130201": "So we have to see, to wait and see.", "dotA3wGqCjM-00363-00130201-00130494": "And once we will be able to make sure that", "dotA3wGqCjM-00364-00130494-00130870": "it was already patched, we will release the PLC", "dotA3wGqCjM-00365-00130870-00131240": "in the GitHub repository that you published on the channel.", "dotA3wGqCjM-00366-00131240-00131740": "And we will also provide a writeup, technical blog post.", "dotA3wGqCjM-00367-00131814-00132105": "So wait and see. We will message them on Twitter as well,", "dotA3wGqCjM-00368-00132105-00132288": "once it will be the deployed.", "dotA3wGqCjM-00369-00132698-00133004": "And then, you know the last thing I wanted to say,", "dotA3wGqCjM-00370-00133004-00133268": "Tomer, if you want to add something somewhere, go ahead.", "dotA3wGqCjM-00371-00133268-00133614": "But I think that it was very interesting research", "dotA3wGqCjM-00372-00133782-00134118": "and we provided all of our technical materials", "dotA3wGqCjM-00373-00134118-00134365": "in our GitHub repository.", "dotA3wGqCjM-00374-00134365-00134666": "And if anyone would like to continue", "dotA3wGqCjM-00375-00134666-00134874": "to research the same area or something,", "dotA3wGqCjM-00376-00134874-00135069": "if you have any questions, go ahead.", "dotA3wGqCjM-00377-00135069-00135201": "You can DM me on Twitter.", "dotA3wGqCjM-00378-00135201-00135618": "You can mention me and we'll be glad.", "dotA3wGqCjM-00379-00135618-00136006": "Tomer and I, to help someone to keep, I think we,", "dotA3wGqCjM-00380-00136006-00136415": "there are a lot of other areas which are related", "dotA3wGqCjM-00381-00136415-00136658": "not even on the repository itself", "dotA3wGqCjM-00382-00136658-00136885": "but even in the repository itself, it's a huge mechanism", "dotA3wGqCjM-00383-00136885-00137194": "and there are a lot of things to keep on investigating", "dotA3wGqCjM-00384-00137194-00137277": "and we didn't have much time.", "dotA3wGqCjM-00385-00137277-00137630": "So if anyone would like to do it", "dotA3wGqCjM-00386-00137630-00137854": "and would like some help, go ahead.", "dotA3wGqCjM-00387-00138041-00138251": "- Yeah, (mumbles)", "dotA3wGqCjM-00388-00138461-00138700": "- Okay, well, so I'd really like to thank you guys", "dotA3wGqCjM-00389-00138700-00138875": "for the talk, you guys did.", "dotA3wGqCjM-00390-00138875-00139106": "I wanna congratulate you again on your first time", "dotA3wGqCjM-00391-00139106-00139582": "at DEF CON and if dropping two or days for a DEF CON", "dotA3wGqCjM-00392-00139582-00139888": "is what we can see in the future from you guys.", "dotA3wGqCjM-00393-00139888-00140200": "I'm sure we'll be inviting you back next year.", "dotA3wGqCjM-00394-00140200-00140283": "So thank you all.", "dotA3wGqCjM-00395-00140283-00140468": "- Thank you very much, it was a pleasure.", "dotA3wGqCjM-00396-00140468-00140812": "- It was fun and we have started to work on it.", "dotA3wGqCjM-00397-00140812-00140926": "- Thanks and stay tuned."}}, {"audio_id": "d0hIbgTywN8", "text": {"d0hIbgTywN8-00000-00000451-00000738": "NDTV Promoter Prannoy Roy | Ghamasan News", "d0hIbgTywN8-00001-00000738-00000938": "NDTV Promoter Prannoy Roy | Ghamasan News", "d0hIbgTywN8-00002-00000938-00000988": "NDTV Promoter Prannoy Roy | Ghamasan News", "d0hIbgTywN8-00003-00001033-00001233": "NDTV Promoter Prannoy Roy | Ghamasan News", "d0hIbgTywN8-00004-00001233-00001283": "NDTV Promoter Prannoy Roy | Ghamasan News", 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perform an asset allocation. In the talk show we cover stock market news,", "d0xaiUr2AyI-00002-00000992-00001752": "Investing in Practice, Tech vs Fund, FIRE and of course crypto. In addition,", "d0xaiUr2AyI-00003-00001762-00002510": "we keep a Kuuske portfolio. Guests like financial influencers and professional", "d0xaiUr2AyI-00004-00002520-00003179": "investors and you have a chance to win nice prizes with Guess the stock! Edgar", "d0xaiUr2AyI-00005-00003189-00003581": "the Haas of Trading Strategy, analyzes Just Eat Take Away in addition, I", "d0xaiUr2AyI-00006-00003591-00004084": "Zita Chengadu, share how you can organize your portfolio finally, you have a chance to win the book", "d0xaiUr2AyI-00007-00004093-00004634": "Philip Fischer's 'Common Stocks and Uncommon Profits' at guess the stock.", "d0xaiUr2AyI-00008-00004715-00005103": "I wonder if you only invest in crypto, are you", "d0xaiUr2AyI-00009-00005113-00005581": "investing? Investing means spreading your money over many things:", "d0xaiUr2AyI-00010-00005629-00005956": "stocks, bonds, digital currency, if you want.", "d0xaiUr2AyI-00011-00005975-00006423": "-But then you are really investing. -Edin already explains it here investing", "d0xaiUr2AyI-00012-00006433-00006744": "means to maintain a portfolio of various investments.", "d0xaiUr2AyI-00013-00006754-00007088": "To put together a portfolio in this way, you will perform an asset allocation.", "d0xaiUr2AyI-00014-00007098-00007545": "This actually represents your risk profile and your portfolio consists of several", "d0xaiUr2AyI-00015-00007555-00008019": "types of assets or asset classes. Asset classes consist of cash,", "d0xaiUr2AyI-00016-00008029-00008451": "fixed income equities and alternative investments. Cash is your buffer stock", "d0xaiUr2AyI-00017-00008461-00008766": "you can purchase in different ways, fixed interest are loans", "d0xaiUr2AyI-00018-00008776-00009206": "you spend and alternative investments such as real estate", "d0xaiUr2AyI-00019-00009216-00010047": "or commodity for example, wine, coffee, gas, oil and of course crypto. I", "d0xaiUr2AyI-00020-00010056-00010338": "wrote down, for you, three different types of strategies these can be", "d0xaiUr2AyI-00021-00010348-00010759": "found at www.kuuske.com/tech-vs-fund.", "d0xaiUr2AyI-00022-00010769-00011198": "I put together the Kuuske portfolio according to the rule of thumb 100 minus, your own age,", "d0xaiUr2AyI-00023-00011208-00011718": "in my case 26, as you can read in the Kuuske blog. From both", "d0xaiUr2AyI-00024-00011727-00012206": "I then take off percentages and divide them among alternative assets. I do not use", "d0xaiUr2AyI-00025-00012216-00012669": "the 60, 40 strategy because I am younger and therefore have a longer horizon", "d0xaiUr2AyI-00026-00012681-00013058": "and am willing and able to take more risks. I", "d0xaiUr2AyI-00027-00013069-00013493": "checked it with the expert Edin Mujagic and he thinks it's a nice mix with a good", "d0xaiUr2AyI-00028-00013503-00013943": "scatter. -Yes, hello I want to talk with you today", "d0xaiUr2AyI-00029-00013953-00014354": "about the Just Eatk Take Away stock. We know the share of", "d0xaiUr2AyI-00030-00014364-00015008": "formerly TakeAway.com. It's home delivery.nl. Merged at the beginning of 2020", "d0xaiUr2AyI-00031-00015019-00015577": "with Just Eat from the UK and now Just Eat Take Away. I already said:", "d0xaiUr2AyI-00032-00015588-00016109": "early 2020, on the eve of the corona pandemic. Yes, then you would say:", "d0xaiUr2AyI-00033-00016119-00016541": "someone or a company that works on home delivery and the like and quite a bit", "d0xaiUr2AyI-00034-00016552-00017044": "growing is right when of course the corona pandemic is there, catering is closed,", "d0xaiUr2AyI-00035-00017080-00017486": "you would say: well, they have the wind at their back! It seemed so for a while", "d0xaiUr2AyI-00036-00017497-00017813": "I must say. But I have to say, it fell after that", "d0xaiUr2AyI-00037-00017824-00018368": "quite back. And Jitse Groen, from the Dutch branch, indicated. Yes,", "d0xaiUr2AyI-00038-00018378-00018872": "many offices are also closed, so we have a lot less lunches and and with", "d0xaiUr2AyI-00039-00018883-00019311": "overtime and the like. So it was a bit disappointing. You may say:", "d0xaiUr2AyI-00040-00019353-00019712": "fundamentally they have the wind at their backs. But maybe it is", "d0xaiUr2AyI-00041-00019722-00020279": "the share well afterwards, in those months afterwards, in 2020 and later also quite", "d0xaiUr2AyI-00042-00020289-00020723": "was going down. They have been above 100 euros for a while and just to indicate.", "d0xaiUr2AyI-00043-00020733-00021302": "They are now around 50. Well, they operate in a very dynamic market.", "d0xaiUr2AyI-00044-00021313-00021786": "so that gives a lot of dynamism and growth. Many players. We know Uber Eats, well,", "d0xaiUr2AyI-00045-00021796-00022259": "Deliveroo of course, you name it. And what we expect", "d0xaiUr2AyI-00046-00022269-00022808": "Fundamentally speaking, of course, Just Eat Take Away is a takeover candidate", "d0xaiUr2AyI-00047-00022819-00023286": "because you can see that the growth is back", "d0xaiUr2AyI-00048-00023296-00023900": "in recent times they gave late still. In 2021 we will have 33 percent more", "d0xaiUr2AyI-00049-00023911-00024428": "received orders. But we still make a loss and we have made a difficult", "d0xaiUr2AyI-00050-00024438-00024815": "investments, of course in the United States. So yes, that share", "d0xaiUr2AyI-00051-00024825-00025214": "only kept going down a bit, it was still a bit disappointing. But what", "d0xaiUr2AyI-00052-00025225-00025642": "you Jitse Groen said, we have already made most of the losses and investments,", "d0xaiUr2AyI-00053-00025669-00026276": "the growth in the european union is very good and yes, the us is still falling", "d0xaiUr2AyI-00054-00026286-00026722": "a bit against and overall still a loss. It is fundamentally", "d0xaiUr2AyI-00055-00026733-00027191": "a takeover candidate that is the fundamental story. On the other hand", "d0xaiUr2AyI-00056-00027201-00027589": "If we also look technically, we see that we already have a number of years ago", "d0xaiUr2AyI-00057-00027613-00028175": "the price of Just Eat Take Away remained around 45 euros. Now has a top", "d0xaiUr2AyI-00058-00028185-00028658": "had just above 100 euros then dropped back. We see that it is therefore finds support", "d0xaiUr2AyI-00059-00028669-00029241": "a technical support around that 45 euros. So as far as we're concerned it's to buy around", "d0xaiUr2AyI-00060-00029251-00029975": "45 to 50 euros. We always work with a stop loose, because it is real", "d0xaiUr2AyI-00061-00029985-00030357": "not that if that market continues to fall and after hope comes despair, then", "d0xaiUr2AyI-00062-00030367-00030760": "you just get out. So now we're going to buy on the technical support. Of", "d0xaiUr2AyI-00063-00030770-00031236": "of course the possible takeover in the back of our minds. Price target is 80 euros.", "d0xaiUr2AyI-00064-00031255-00031494": "-Yes. -And we keep the stop loose at ten", "d0xaiUr2AyI-00065-00031504-00032067": "percent, like you buy around, say, around 45. Then you stop", "d0xaiUr2AyI-00066-00032077-00032652": "even at 40 euros. So fundamental and technical buy signal Just Eat Take Away!", "d0xaiUr2AyI-00067-00032832-00033163": "Edgar de Haas, from Trading Strategy thanks for the fundamental as well as", "d0xaiUr2AyI-00068-00033173-00033669": "the technical analysis JET will be added to the Kuuske portfolio and now", "d0xaiUr2AyI-00069-00033679-00034079": "you know how to put together a portfolio, I'm curious about your", "d0xaiUr2AyI-00070-00034089-00034704": "portfolio strategy. Then send it to reactie@kuuske.com ! Kuuske thanks", "d0xaiUr2AyI-00071-00034714-00035001": "her friends VanEck and BeursPro who helped make the talk show possible.", "d0xaiUr2AyI-00072-00035035-00035363": "Advice is given in a personal capacity and established independently of Kuuske", "d0xaiUr2AyI-00073-00035373-00035788": "This talk show consists of four blocks: Stock Market News, Investing", "d0xaiUr2AyI-00074-00035798-00036260": "in practice, Tech vs Fund, FIRE & Crypto. Watch listen or read the blocks via", "d0xaiUr2AyI-00075-00036270-00036741": "YouTube, Instagram or on the website: www.kuuske.com As usual", "d0xaiUr2AyI-00076-00036751-00037361": "we finish this show with Guess the Stock. In every talk show, you can win a prize", "d0xaiUr2AyI-00077-00037372-00037760": "by guessing a stock using a riddle. You can fill this in", "d0xaiUr2AyI-00078-00037770-00038263": "at www.Kuuske.com/raadhetshare. The winners will be in the next talk show", "d0xaiUr2AyI-00079-00038273-00038682": "published and can be viewed on the website. Which share/company from", "d0xaiUr2AyI-00080-00038692-00039075": "the NASDAQ binged nicely, but was punished hard only", "d0xaiUr2AyI-00081-00039085-00039513": "but because they do not live up to the too high expectations and therefore the expectation", "d0xaiUr2AyI-00082-00039570-00040058": "burst that resulted in the share price falling by more than 30 percent in one week", "d0xaiUr2AyI-00083-00040069-00040447": "plummeted. Go to www.kuuske.com/raadhetaandeel fill", "d0xaiUr2AyI-00084-00040457-00040710": "the share in and have a chance to win one of the five books 'Common Stocks and Uncommon", "d0xaiUr2AyI-00085-00040720-00040779": "Profits' by Philip Fischer recommended by the successful swing trader Jordi van", "d0xaiUr2AyI-00086-00040789-00041980": "de Pas and Warrent Buffett. Raoul Esseboom of Cryptotakkies shares his clear view", "d0xaiUr2AyI-00087-00041991-00042398": "on the crypto world. Roy Kuuske follower shares his experience. In addition, share", "d0xaiUr2AyI-00088-00042408-00042642": "i Zita Chengadu, which is personal finance."}}, {"audio_id": "d0BKSf868F0", "text": {"d0BKSf868F0-00000-00010893-00012974": "so the 2008 rights and parents as well because the issue is sitting there and", "d0BKSf868F0-00001-00012974-00015113": "then go back home so it was a bridge or go to use social media recently I say it", "d0BKSf868F0-00002-00015113-00018045": "back I see big so I like I like I said I knew the house so what it is I don't go", "d0BKSf868F0-00003-00018045-00019091": "upside approach this is where I was and I", "d0BKSf868F0-00004-00019091-00020516": "improves because I go to keep all the time and you go and you build from there", "d0BKSf868F0-00005-00020516-00020995": "I remember", "d0BKSf868F0-00006-00021075-00026225": "I was like I don't want an end but in my mind it was so what we have video from", "d0BKSf868F0-00007-00026225-00026525": "this journey", "d0BKSf868F0-00008-00035080-00042471": "is going to go I remember who was there with one's goals but I", "d0BKSf868F0-00009-00042840-00045625": "huge so we should remember is that what happened in the series or in the opening", "d0BKSf868F0-00010-00045625-00047313": "plenary over and over and it's just a little bigger", "d0BKSf868F0-00011-00047661-00049711": "many awards and industry and the bigger room", "d0BKSf868F0-00012-00049859-00053166": "but at the time this is not to national when I was going to ensure however I", "d0BKSf868F0-00013-00053166-00054480": "just an excuse to tell you", "d0BKSf868F0-00014-00054480-00055859": "business where it was so I say so", "d0BKSf868F0-00015-00056516-00056573": "lol"}}, {"audio_id": "d0P0Us2qU40", "text": {"d0P0Us2qU40-00000-00001100-00001900": "ELECTION ANALYSIS: Wikileaks Honest Reports on Crooked Hillary More Viral than Lapdog Media Agitprop.", "d0P0Us2qU40-00001-00002000-00003000": "The liberal media’s best efforts to influence the election in favor of Hillary Clinton could not match the honest analysis of Wikileaks.", "d0P0Us2qU40-00002-00003100-00004800": "A new report on the 2016 election by Qatar Computing Research Institute found that Wikileaks had more of an impact in the 2016 election on social media than the liberal media agitprop defending Crooked Hillary Clinton.", "d0P0Us2qU40-00003-00004900-00006600": "Hillary Clinton had about twice as many attacking tweets than supportive tweets. President Trump had more than twice as many supportive tweets than attacking tweets. Attacks against Clinton focused on her character and on the WikiLeaks leaks.", "d0P0Us2qU40-00004-00006700-00008100": "The researchers concluded that although Trump received more negative coverage than Clinton in the mainstream media, Trump benefited from many more tweets that are either supporting him or attacking Crooked Hillary.", "d0P0Us2qU40-00005-00008200-00010100": "The study found 63% of the volume of viral content on US election were in Trump’s favor compared to only 37% in favor of the loser, Hillary Clinton. In conclusion: The media and elites loved Crooked Hillary, the people loved Trump."}}, {"audio_id": "d0RHIII5bYM", "text": {"d0RHIII5bYM-00001-00000200-00000400": "What is wrong with them"}}, {"audio_id": "d0UEHt6p0gu", "text": {"d0UEHt6p0gu-00000-00000156-00000758": "We already live in a construct of reality. So, the idea that we could create a virtual environment that is as", "d0UEHt6p0gu-00001-00000770-00001323": "real or less real is a complicated question, because -- just because it's virtual doesn't mean it's not real.", "d0UEHt6p0gu-00002-00001363-00001838": "Given enough complexity of the stimuli, it could be indistinguishable.", "d0UEHt6p0gu-00003-00002500-00002718": "Right now, we're inside a computer program?", "d0UEHt6p0gu-00004-00002755-00002891": "Is it really so hard to believe?", "d0UEHt6p0gu-00005-00003005-00003070": "This isn't real?", "d0UEHt6p0gu-00006-00003138-00003489": "Real is simply electrical signals interpreted by your brain.", "d0UEHt6p0gu-00007-00003892-00004054": "Somebody will appear on that rooftop", "d0UEHt6p0gu-00008-00004060-00004346": "and fire an RPG at your vehicle.", "d0UEHt6p0gu-00009-00004840-00005208": "Virtual Reality Exposure Therapy is a method whereby", "d0UEHt6p0gu-00010-00005208-00005480": "you take somebody with an anxiety disorder", "d0UEHt6p0gu-00011-00005480-00005788": "and you gradually expose them to what they're afraid of.", "d0UEHt6p0gu-00012-00005810-00006250": "With Post-Traumatic Stress Disorder, we're taking people that have been tramatized", "d0UEHt6p0gu-00013-00006250-00006900": "and we're trying to help them to confront and process these difficult emotional expriences", "d0UEHt6p0gu-00014-00006900-00007415": "in a graduated way, at a pace they can handle, and if they stay with it long enough... Because", "d0UEHt6p0gu-00015-00007417-00007806": "nothing really bad happens, eventually the anxiety starts to extinguish.", "d0UEHt6p0gu-00016-00007825-00008460": "As soon as you get into one of those environments that you recognize, it immediately brings you back. Those", "d0UEHt6p0gu-00017-00008478-00008983": "experiences are very deep and they mean a lot. So when you're able to be put into that situation again,", "d0UEHt6p0gu-00018-00009034-00009173": "that's a pretty powerful sensation.", "d0UEHt6p0gu-00019-00009448-00009969": "When you tell people what you do, a lot of times they give me a funny look like, \"Why the hell would you do that?", "d0UEHt6p0gu-00020-00009974-00010584": "Why are you torturing these service members, making them go through it all over again?\" And my answer", "d0UEHt6p0gu-00021-00010593-00010791": "is really simple. We do it because it works.", "d0UEHt6p0gu-00022-00011425-00011517": "That is pretty incredible.", "d0UEHt6p0gu-00023-00011676-00012324": "Neuroplasticity is the phenomena by which our brains modify itself in response to interactions with the environment.", "d0UEHt6p0gu-00024-00012328-00012638": "Plasticity has no morality. It will go in a direction", "d0UEHt6p0gu-00025-00012638-00012984": "that the interactions take it. So, if your", "d0UEHt6p0gu-00026-00012984-00013352": "interactivity leads to a negative outcome,", "d0UEHt6p0gu-00027-00013352-00013780": "there is certainly the danger that they can have a negative impact on people's psychology.", "d0UEHt6p0gu-00028-00014061-00014620": "There's a fairly robust literature that scientists largely agree upon, that if you play violent video games", "d0UEHt6p0gu-00029-00014623-00014939": "for many hours a week, you will be more aggressive in the physical world.", "d0UEHt6p0gu-00030-00015096-00015696": "What remains to be seen, is when these experiences become more immersive. So you're playing a game like Grand Theft Auto", "d0UEHt6p0gu-00031-00015840-00016496": "and the blood splatters and you feel it hit your body, and there's Haptic Feedback, that when a body", "d0UEHt6p0gu-00032-00016503-00016670": "falls on you, it actually knocks you over.", "d0UEHt6p0gu-00033-00016834-00017396": "I think an important question that people need to ask is, \"What happens when people have these very violent", "d0UEHt6p0gu-00034-00017401-00017608": "experiences that the brain treats as real?\"", "d0UEHt6p0gu-00035-00017952-00018048": "We wanna do the opposite.", "d0UEHt6p0gu-00036-00018118-00018366": "If you give someone a VR experience, it's very intense.", "d0UEHt6p0gu-00037-00018366-00018624": "And instead of killing somebody they're saving someone's life.", "d0UEHt6p0gu-00038-00018652-00019136": "Will that experience transfer? With the Hero Study, you literally become a hero, and you", "d0UEHt6p0gu-00039-00019156-00019672": "become Superwoman or Superman by using your body to fly around. The wind is rushing through your hair.", "d0UEHt6p0gu-00040-00019697-00020174": "The floor is shaking. You then save a child's life. The control condition is maybe you rode in a helicopter.", "d0UEHt6p0gu-00041-00020214-00020749": "When you fly like a hero and save a child's life, you're more helpful to someone that has an accident outside", "d0UEHt6p0gu-00042-00020756-00021218": "of VR, compared to, if you didn't get that gift of having a superpower and using it for good.", "d0UEHt6p0gu-00043-00021291-00021805": "In the same way a single experience in your lifetime can be transformational, so can a well-crafted", "d0UEHt6p0gu-00044-00021810-00021902": "Virtual-Reality experience.", "d0UEHt6p0gu-00045-00021976-00022556": "It's a long-standing philosophical issue that was raised way before movies like, The Matrix, although you see", "d0UEHt6p0gu-00046-00022564-00022870": "a lot of that there. And that's why I think it's a Hollywood favorite.", "d0UEHt6p0gu-00047-00022878-00023318": "While there may be some things that people have questions about with virtual reality, \"Will people become", "d0UEHt6p0gu-00048-00023327-00023822": "addicted to it?\" And so on. I think the good that will come out of this far outweighs the bad.", "d0UEHt6p0gu-00049-00023850-00024547": "We see the virtual reality landscape as an exciting potential for therapeutics to improve the functioning", "d0UEHt6p0gu-00050-00024553-00024913": "of the human brain and hopefully to improve the quality of human life.", "d0UEHt6p0gu-00051-00024925-00025535": "There's ways that we can experience things, ways we can practice interactions with virtual people, ways that", "d0UEHt6p0gu-00052-00025540-00026257": "we can see things that we've never seen before or never will see. This technology stands to open up a world", "d0UEHt6p0gu-00053-00026270-00026483": "that we can only imagine at this point.", "d0UEHt6p0gu-00054-00026701-00027270": "Virtual reality is like Uranium. It can heat homes and it can destroy nations. It's up to us to responsibly", "d0UEHt6p0gu-00055-00027277-00027809": "understand the effects of using these medium, and just to go in with full awareness of how these experiences", "d0UEHt6p0gu-00056-00027821-00027871": "will change us.", "d0UEHt6p0gu-00057-00028041-00028610": "It does question a lot of the core assumptions we have of what it is to interact in reality", "d0UEHt6p0gu-00058-00028615-00028686": "in the first place."}}, {"audio_id": "d0a9CzBM4xE", "text": {"d0a9CzBM4xE-00000-00001607-00002304": "as we grow older many of us consider purchasing a new home to live in during our golden years more", "d0a9CzBM4xE-00001-00002304-00002880": "and more people choose to live in over 55 plus communities which they call retirement homes", "d0a9CzBM4xE-00002-00002880-00003752": "and enjoy their lives in a 55 plus community or active adult community over 55 plus communities", "d0a9CzBM4xE-00003-00003752-00004488": "have many benefits but there are also problems that you may not be aware of so today i will be", "d0a9CzBM4xE-00004-00004488-00005096": "talking about seven problems or issues that you may be facing if you consider living in", "d0a9CzBM4xE-00005-00005096-00005784": "a 55 plus community or active adult community please stand by it's coming right after this", "d0a9CzBM4xE-00006-00006792-00007248": "hi there this is lynn alvarez your trusted realtor in charlotte and the surrounding", "d0a9CzBM4xE-00007-00007248-00007816": "areas my husband albert alvarez and i have been working in charlotte and the surrounding areas", "d0a9CzBM4xE-00008-00007816-00008568": "for over 20 years now please make sure to hit the subscribe button below and like this video", "d0a9CzBM4xE-00009-00008568-00009256": "if you feel that it has given you some value while living in an over 55 plus community has many pros", "d0a9CzBM4xE-00010-00009312-00009944": "there are also cons so make sure you understand the potential downsides before making this big", "d0a9CzBM4xE-00011-00009944-00010784": "decision in your life here are the seven biggest problems with over 55 plus communities homes are", "d0a9CzBM4xE-00012-00010784-00011552": "expensive here in the charlotte area homes in 55 plus communities are expensive nowadays depending", "d0a9CzBM4xE-00013-00011552-00012320": "on the location size of the home and the amenities they offer houses in all their communities run", "d0a9CzBM4xE-00014-00012320-00013176": "from $395,000 for a small 1400 square foot home to seven hundred thousand dollars for larger homes", "d0a9CzBM4xE-00015-00013176-00013960": "new construction homes are more expensive from mid $400s to high $800s homes are smaller", "d0a9CzBM4xE-00016-00014016-00014704": "downsizing to a smaller home isn't necessarily a negative roughly two-thirds retirees consider", "d0a9CzBM4xE-00017-00014704-00015304": "moving into a smaller home when they finish working smaller homes require less maintenance", "d0a9CzBM4xE-00018-00015360-00016224": "the utility bills are lower and moving can free up cash high hoa dues the hoa dues in most 55", "d0a9CzBM4xE-00019-00016224-00016856": "plus communities in north carolina specifically 55 plus communities in the charlotte area are high", "d0a9CzBM4xE-00020-00016944-00017720": "they run from $250 dollars to $425 dollars per month hoi dues are higher than regular communities", "d0a9CzBM4xE-00021-00017720-00018440": "because they include yard maintenance and great amenities and some communities include water cable", "d0a9CzBM4xE-00022-00018440-00019296": "and club memberships in the monthly hoa fees lack of age diversity since active adult communities", "d0a9CzBM4xE-00023-00019296-00020000": "usually require a minimum of one person in the residence be at least 55 years old there is a", "d0a9CzBM4xE-00024-00020000-00020728": "lack of age diversity within the community unless family members with children are visiting however", "d0a9CzBM4xE-00025-00020728-00021424": "there are some young residents that are still working full-time no care services are included", "d0a9CzBM4xE-00026-00021504-00022112": "active adult communities or 55 plus communities do not provide health care services of any kind", "d0a9CzBM4xE-00027-00022112-00022808": "as part of the monthly hoa fees these communities are not retirement centers or assisted living", "d0a9CzBM4xE-00028-00022808-00023568": "facilities basically 55 plus communities would fall under the same category as aging at home", "d0a9CzBM4xE-00029-00023632-00024096": "if you are looking for communities that provide senior services you should be", "d0a9CzBM4xE-00030-00024096-00024920": "looking at assisted living facilities cliques and gossips most of the residents are no longer", "d0a9CzBM4xE-00031-00024920-00025504": "working and with so much time on their hands they tend to get into other people's business", "d0a9CzBM4xE-00032-00025616-00026248": "they complain a lot and whine a lot about everything the facebook group in the neighborhood", "d0a9CzBM4xE-00033-00026248-00026864": "is where you usually read all the complaints and frustrations of some noisy neighbors", "d0a9CzBM4xE-00034-00026952-00027576": "your friends might pass away people move into age-restricted 55-plus communities", "d0a9CzBM4xE-00035-00027576-00028256": "with the intention of meeting new friends there unfortunately these communities have a fairly high", "d0a9CzBM4xE-00036-00028256-00029032": "mortality rate it is a tragic experience watching friends and neighbors pass away even though there", "d0a9CzBM4xE-00037-00029032-00029583": "are problems in 55 black communities there are lots of benefits to enjoy your life to the fullest", "d0a9CzBM4xE-00038-00029648-00030264": "check it out i'd like to hear your thoughts about living in 55 plus communities or active", "d0a9CzBM4xE-00039-00030264-00030880": "adult communities so please leave your comment below if you're thinking of moving into one of", "d0a9CzBM4xE-00040-00030880-00031480": "the communities in charlotte and the surrounding areas please let us know how we can help you", "d0a9CzBM4xE-00041-00031583-00032239": "visit our website charlotteactiveadults.com to search for homes for sale in charlotte lake", "d0a9CzBM4xE-00042-00032239-00032840": "norman and other places where you can enjoy your retirement years here in charlotte north carolina", "d0a9CzBM4xE-00043-00032944-00033392": "once again my name is lynn alvarez with the ally group real estate please don't forget", "d0a9CzBM4xE-00044-00033392-00033944": "to subscribe to our channel below you may be interested to watch other videos right here", "d0a9CzBM4xE-00045-00034080-00034768": "if you are relocating to charlotte please see the description below and get a free relocation guide", "d0a9CzBM4xE-00046-00034832-00035856": "thanks so much for watching i hope to see you on my next video have a great day and bye for now"}}, {"audio_id": "d16nSb94YxU", "text": {"d16nSb94YxU-00000-00000119-00000319": "Like & subscribe"}}, {"audio_id": "d1uPcGUsn5E", "text": {"d1uPcGUsn5E-00000-00000687-00001258": "White House: Hamas To Blame for Continued Violence, Israel Has Right to ‘Defend Itself’", "d1uPcGUsn5E-00001-00001258-00001702": "As officials and dignitaries gathered in Jerusalem to celebrate the move of America’s embassy", "d1uPcGUsn5E-00002-00001702-00002121": "in Israel, Palestinian protesters gathered at the border on Monday armed with rocks and", "d1uPcGUsn5E-00003-00002121-00002333": "incendiary devices.", "d1uPcGUsn5E-00004-00002333-00002767": "When dozens of Palestinians were killed, world leaders including French President Emmanuel", "d1uPcGUsn5E-00005-00002767-00003142": "Macron condemned a deadly reaction from Israeli forces.", "d1uPcGUsn5E-00006-00003142-00003670": "American officials, however, placed the blame squarely on the Palestinian side, citing the", "d1uPcGUsn5E-00007-00003670-00004069": "influence of U.S.-designated terror organization Hamas.", "d1uPcGUsn5E-00008-00004069-00004455": "The first question during a White House press briefing on Monday sought a reaction from", "d1uPcGUsn5E-00009-00004455-00004753": "the Trump administration regarding the deaths along the border.", "d1uPcGUsn5E-00010-00004753-00005233": "“We’re aware of the reports of continued violence in Gaza today,” White House principal", "d1uPcGUsn5E-00011-00005233-00005710": "deputy press secretary Raj Shah said in what appeared to be prepared remarks.", "d1uPcGUsn5E-00012-00005710-00006148": "He went on to declare that the “responsibility for these tragic deaths rests squarely with", "d1uPcGUsn5E-00013-00006148-00006248": "Hamas.”", "d1uPcGUsn5E-00014-00006248-00006675": "United States Ambassador to the United Nations Nikki Haley echoed that position in comments", "d1uPcGUsn5E-00015-00006675-00006847": "she made the following morning.", "d1uPcGUsn5E-00016-00006847-00007289": "“This is how determined they are to make the lives of the Palestinian people miserable,”", "d1uPcGUsn5E-00017-00007289-00007401": "she said.", "d1uPcGUsn5E-00018-00007401-00007881": "Haley cited reports that the Hamas-backed protesters “light Molotov cocktails, attached", "d1uPcGUsn5E-00019-00007881-00008454": "to kits on fire, and attempt to fly them into Israel to cause as much destruction as possible.”", "d1uPcGUsn5E-00020-00008454-00008884": "She claimed other nations would not abide such provocations at their own borders.", "d1uPcGUsn5E-00021-00008884-00009367": "“No country in this chamber would act with more restraint than Israel has,” Haley said.", "d1uPcGUsn5E-00022-00009367-00009850": "“In fact, the records of several countries here today suggest they would be much less", "d1uPcGUsn5E-00023-00009850-00009950": "restrained.”", "d1uPcGUsn5E-00024-00009950-00010438": "Newly confirmed Secretary of State Mike Pompeo reacted similarly late last month in reaction", "d1uPcGUsn5E-00025-00010438-00010714": "to escalating violence along the Gaza Strip.", "d1uPcGUsn5E-00026-00010714-00011146": "“We do believe the Israelis have the right to defend themselves and we are fully supportive", "d1uPcGUsn5E-00027-00011146-00011514": "of that,” he said, according to CBS News.", "d1uPcGUsn5E-00028-00011514-00011914": "Pompeo did not meet with Palestinian officials during the Middle East trip during which he", "d1uPcGUsn5E-00029-00011914-00012074": "made those remarks.", "d1uPcGUsn5E-00030-00012074-00012459": "He did express America’s continued willingness to pursue a two-state solution with the goal", "d1uPcGUsn5E-00031-00012459-00012642": "of lasting peace in the region.", "d1uPcGUsn5E-00032-00012642-00013100": "“An important piece of achieving Middle East stability is to resolve this conflict,”", "d1uPcGUsn5E-00033-00013100-00013200": "he said.", "d1uPcGUsn5E-00034-00013200-00013624": "“Precisely how to rank it among all the various challenges, I’ll defer on that.", "d1uPcGUsn5E-00035-00013624-00014119": "Know that it is (an) incredible priority for the United States to provide whatever assistance", "d1uPcGUsn5E-00036-00014119-00014459": "we can to allow the two parties to come to a resolution.”", "d1uPcGUsn5E-00037-00014459-00014879": "Shah cited Pompeo’s prior comments in his statement to reporters on Monday.", "d1uPcGUsn5E-00038-00014879-00015359": "“Hamas is intentionally and cynically provoking this response and as the secretary of state", "d1uPcGUsn5E-00039-00015359-00016606": "said, ‘Israel has the right to defend itself.'”"}}, {"audio_id": "d1_QrIx_Gj4", "text": {"d1_QrIx_Gj4-00000-00000010-00000116": "ATTEMPTED COERCION AND", "d1_QrIx_Gj4-00001-00000116-00000123": "ATTEMPTED COERCION AND", "d1_QrIx_Gj4-00002-00000123-00000250": "ATTEMPTED COERCION AND ENTICEMENT OF A MINOR.", "d1_QrIx_Gj4-00003-00000250-00000256": "ATTEMPTED COERCION AND ENTICEMENT OF A MINOR.", "d1_QrIx_Gj4-00004-00000256-00000387": "ATTEMPTED COERCION AND ENTICEMENT OF A MINOR. >>> BELTRAMI COUNTY DEPUTY", "d1_QrIx_Gj4-00005-00000387-00000393": "ENTICEMENT OF A MINOR. >>> BELTRAMI COUNTY DEPUTY", "d1_QrIx_Gj4-00006-00000393-00000543": "ENTICEMENT OF A MINOR. >>> BELTRAMI COUNTY DEPUTY SHERIFF JEFF ROBERTS AND HIS", "d1_QrIx_Gj4-00007-00000543-00000550": ">>> BELTRAMI COUNTY DEPUTY SHERIFF JEFF ROBERTS AND HIS", "d1_QrIx_Gj4-00008-00000550-00000663": ">>> BELTRAMI COUNTY DEPUTY SHERIFF JEFF ROBERTS AND HIS WIFE, LINDA ROBERTS, WERE", "d1_QrIx_Gj4-00009-00000663-00000670": "SHERIFF JEFF ROBERTS AND HIS WIFE, LINDA ROBERTS, WERE", "d1_QrIx_Gj4-00010-00000670-00000814": "SHERIFF JEFF ROBERTS AND HIS WIFE, LINDA ROBERTS, WERE RECENTLY HONORED AND PRESENTED", "d1_QrIx_Gj4-00011-00000814-00000820": "WIFE, LINDA ROBERTS, WERE RECENTLY HONORED AND PRESENTED", "d1_QrIx_Gj4-00012-00000820-00001044": "WIFE, LINDA ROBERTS, WERE RECENTLY HONORED AND PRESENTED AWARDS FROM THE WYOMING HIGHWAY", "d1_QrIx_Gj4-00013-00001044-00001051": "RECENTLY HONORED AND PRESENTED AWARDS FROM THE WYOMING HIGHWAY", "d1_QrIx_Gj4-00014-00001051-00001197": "RECENTLY HONORED AND PRESENTED AWARDS FROM THE WYOMING HIGHWAY PATROL ASSOCIATION AT A CEREMONY", "d1_QrIx_Gj4-00015-00001197-00001204": "AWARDS FROM THE WYOMING HIGHWAY PATROL ASSOCIATION AT A CEREMONY", "d1_QrIx_Gj4-00016-00001204-00001391": "AWARDS FROM THE WYOMING HIGHWAY PATROL ASSOCIATION AT A CEREMONY RECENTLY HELD AT THE BELTRAMI", "d1_QrIx_Gj4-00017-00001391-00001398": "PATROL ASSOCIATION AT A CEREMONY RECENTLY HELD AT THE BELTRAMI", "d1_QrIx_Gj4-00018-00001398-00001528": "PATROL ASSOCIATION AT A CEREMONY RECENTLY HELD AT THE BELTRAMI COUNTY LAW ENFORCEMENT CENTER.", "d1_QrIx_Gj4-00019-00001528-00001534": "RECENTLY HELD AT THE BELTRAMI COUNTY LAW ENFORCEMENT CENTER.", "d1_QrIx_Gj4-00020-00001534-00001681": "RECENTLY HELD AT THE BELTRAMI COUNTY LAW ENFORCEMENT CENTER. THE AWARDS WERE PRESENTED BY", "d1_QrIx_Gj4-00021-00001681-00001688": "COUNTY LAW ENFORCEMENT CENTER. THE AWARDS WERE PRESENTED BY", "d1_QrIx_Gj4-00022-00001688-00001908": "COUNTY LAW ENFORCEMENT CENTER. THE AWARDS WERE PRESENTED BY MINNESOTA STATE PATROL CAPTAIN", "d1_QrIx_Gj4-00023-00001908-00001915": "THE AWARDS WERE PRESENTED BY MINNESOTA STATE PATROL CAPTAIN", "d1_QrIx_Gj4-00024-00001915-00002118": "THE AWARDS WERE PRESENTED BY MINNESOTA STATE PATROL CAPTAIN MIKE WEDIN AND SHERIFF PHIL", "d1_QrIx_Gj4-00025-00002118-00002125": "MINNESOTA STATE PATROL CAPTAIN MIKE WEDIN AND SHERIFF PHIL", "d1_QrIx_Gj4-00026-00002125-00002332": "MINNESOTA STATE PATROL CAPTAIN MIKE WEDIN AND SHERIFF PHIL HODAPP ON BEHALF OF THE WYOMING", "d1_QrIx_Gj4-00027-00002332-00002338": "MIKE WEDIN AND SHERIFF PHIL HODAPP ON BEHALF OF THE WYOMING", "d1_QrIx_Gj4-00028-00002338-00002726": "MIKE WEDIN AND SHERIFF PHIL HODAPP ON BEHALF OF THE WYOMING HIGHWAY PATROL ASSOCIATION FOR", "d1_QrIx_Gj4-00029-00002726-00002732": "HODAPP ON BEHALF OF THE WYOMING HIGHWAY PATROL ASSOCIATION FOR", "d1_QrIx_Gj4-00030-00002732-00002902": "HODAPP ON BEHALF OF THE WYOMING HIGHWAY PATROL ASSOCIATION FOR THE EFFORTS OF THE ROBERTS TO", "d1_QrIx_Gj4-00031-00002902-00002909": "HIGHWAY PATROL ASSOCIATION FOR THE EFFORTS OF THE ROBERTS TO", "d1_QrIx_Gj4-00032-00002909-00003113": "HIGHWAY PATROL ASSOCIATION FOR THE EFFORTS OF THE ROBERTS TO SAVE THE LIFE OF A WYOMING", "d1_QrIx_Gj4-00033-00003113-00003119": "THE EFFORTS OF THE ROBERTS TO SAVE THE LIFE OF A WYOMING", "d1_QrIx_Gj4-00034-00003119-00003226": "THE EFFORTS OF THE ROBERTS TO SAVE THE LIFE OF A WYOMING HIGHWAY PATROL TROOPER INVOLVED", "d1_QrIx_Gj4-00035-00003226-00003233": "SAVE THE LIFE OF A WYOMING HIGHWAY PATROL TROOPER INVOLVED", "d1_QrIx_Gj4-00036-00003233-00003359": "SAVE THE LIFE OF A WYOMING HIGHWAY PATROL TROOPER INVOLVED IN A MOTOR VEHICLE COLLISION ON", "d1_QrIx_Gj4-00037-00003359-00003366": "HIGHWAY PATROL TROOPER INVOLVED IN A MOTOR VEHICLE COLLISION ON", "d1_QrIx_Gj4-00038-00003366-00003516": "HIGHWAY PATROL TROOPER INVOLVED IN A MOTOR VEHICLE COLLISION ON SEPTEMBER 22nd OF LAST YEAR.", "d1_QrIx_Gj4-00039-00003516-00003523": "IN A MOTOR VEHICLE COLLISION ON SEPTEMBER 22nd OF LAST YEAR.", "d1_QrIx_Gj4-00040-00003523-00003673": "IN A MOTOR VEHICLE COLLISION ON SEPTEMBER 22nd OF LAST YEAR. THE ROBERTS WERE VACATIONING AT", "d1_QrIx_Gj4-00041-00003673-00003680": "SEPTEMBER 22nd OF LAST YEAR. THE ROBERTS WERE VACATIONING AT", "d1_QrIx_Gj4-00042-00003680-00003827": "SEPTEMBER 22nd OF LAST YEAR. THE ROBERTS WERE VACATIONING AT THE TIME WITH THEIR FAMILY AND", "d1_QrIx_Gj4-00043-00003827-00003833": "THE ROBERTS WERE VACATIONING AT THE TIME WITH THEIR FAMILY AND", "d1_QrIx_Gj4-00044-00003833-00003973": "THE ROBERTS WERE VACATIONING AT THE TIME WITH THEIR FAMILY AND WERE TRAVELING NEAR SHERIDAN,", "d1_QrIx_Gj4-00045-00003973-00003980": "THE TIME WITH THEIR FAMILY AND WERE TRAVELING NEAR SHERIDAN,", "d1_QrIx_Gj4-00046-00003980-00004114": "THE TIME WITH THEIR FAMILY AND WERE TRAVELING NEAR SHERIDAN, WYOMING ON INTERSTATE 90 WHEN", "d1_QrIx_Gj4-00047-00004114-00004120": "WERE TRAVELING NEAR SHERIDAN, WYOMING ON INTERSTATE 90 WHEN", "d1_QrIx_Gj4-00048-00004120-00004267": "WERE TRAVELING NEAR SHERIDAN, WYOMING ON INTERSTATE 90 WHEN THEY WITNESSED WYOMING STATE", "d1_QrIx_Gj4-00049-00004267-00004274": "WYOMING ON INTERSTATE 90 WHEN THEY WITNESSED WYOMING STATE", "d1_QrIx_Gj4-00050-00004274-00004424": "WYOMING ON INTERSTATE 90 WHEN THEY WITNESSED WYOMING STATE TROOPER DAVID MOTSICK COLLIDE", "d1_QrIx_Gj4-00051-00004424-00004431": "THEY WITNESSED WYOMING STATE TROOPER DAVID MOTSICK COLLIDE", "d1_QrIx_Gj4-00052-00004431-00004617": "THEY WITNESSED WYOMING STATE TROOPER DAVID MOTSICK COLLIDE HEAD-ON WITH A WRONG WAY DRIVER.", "d1_QrIx_Gj4-00053-00004617-00004624": "TROOPER DAVID MOTSICK COLLIDE HEAD-ON WITH A WRONG WAY DRIVER.", "d1_QrIx_Gj4-00054-00004624-00004761": "TROOPER DAVID MOTSICK COLLIDE HEAD-ON WITH A WRONG WAY DRIVER. TROOPER MOTSICK SUFFERED", "d1_QrIx_Gj4-00055-00004761-00004768": "HEAD-ON WITH A WRONG WAY DRIVER. TROOPER MOTSICK SUFFERED", "d1_QrIx_Gj4-00056-00004768-00004934": "HEAD-ON WITH A WRONG WAY DRIVER. TROOPER MOTSICK SUFFERED MULTIPLE AND SIGNIFICANT LIFE", "d1_QrIx_Gj4-00057-00004934-00004941": "TROOPER MOTSICK SUFFERED MULTIPLE AND SIGNIFICANT LIFE", "d1_QrIx_Gj4-00058-00004941-00005071": "TROOPER MOTSICK SUFFERED MULTIPLE AND SIGNIFICANT LIFE THREATENING INJURIES AND DEPUTY", "d1_QrIx_Gj4-00059-00005071-00005078": "MULTIPLE AND SIGNIFICANT LIFE THREATENING INJURIES AND DEPUTY", "d1_QrIx_Gj4-00060-00005078-00005305": "MULTIPLE AND SIGNIFICANT LIFE THREATENING INJURIES AND DEPUTY ROBERTS AND HIS WIFE, LINDA, A", "d1_QrIx_Gj4-00061-00005305-00005311": "THREATENING INJURIES AND DEPUTY ROBERTS AND HIS WIFE, LINDA, A", "d1_QrIx_Gj4-00062-00005311-00005465": "THREATENING INJURIES AND DEPUTY ROBERTS AND HIS WIFE, LINDA, A NORTH MEMORIAL AIR CARE FLIGHT", "d1_QrIx_Gj4-00063-00005465-00005472": "ROBERTS AND HIS WIFE, LINDA, A NORTH MEMORIAL AIR CARE FLIGHT", "d1_QrIx_Gj4-00064-00005472-00005635": "ROBERTS AND HIS WIFE, LINDA, A NORTH MEMORIAL AIR CARE FLIGHT PARAMEDIC STOPPED AND RENDERED", "d1_QrIx_Gj4-00065-00005635-00005642": "NORTH MEMORIAL AIR CARE FLIGHT PARAMEDIC STOPPED AND RENDERED", "d1_QrIx_Gj4-00066-00005642-00005789": "NORTH MEMORIAL AIR CARE FLIGHT PARAMEDIC STOPPED AND RENDERED IMMEDIATE AID TO THE TROOPER AND", "d1_QrIx_Gj4-00067-00005789-00005795": "PARAMEDIC STOPPED AND RENDERED IMMEDIATE AID TO THE TROOPER AND", "d1_QrIx_Gj4-00068-00005795-00005932": "PARAMEDIC STOPPED AND RENDERED IMMEDIATE AID TO THE TROOPER AND THE DRIVER OF THE OTHER VEHICLE.", "d1_QrIx_Gj4-00069-00005932-00005939": "IMMEDIATE AID TO THE TROOPER AND THE DRIVER OF THE OTHER VEHICLE.", "d1_QrIx_Gj4-00070-00005939-00006049": "IMMEDIATE AID TO THE TROOPER AND THE DRIVER OF THE OTHER VEHICLE. DESPITE THEIR EFFORTS, THE", "d1_QrIx_Gj4-00071-00006049-00006056": "THE DRIVER OF THE OTHER VEHICLE. DESPITE THEIR EFFORTS, THE", "d1_QrIx_Gj4-00072-00006056-00006162": "THE DRIVER OF THE OTHER VEHICLE. DESPITE THEIR EFFORTS, THE DRIVER OF THE OTHER VEHICLE", "d1_QrIx_Gj4-00073-00006162-00006169": "DESPITE THEIR EFFORTS, THE DRIVER OF THE OTHER VEHICLE", "d1_QrIx_Gj4-00074-00006169-00006326": "DESPITE THEIR EFFORTS, THE DRIVER OF THE OTHER VEHICLE DIED, BUT TROOPER MOTSICK", "d1_QrIx_Gj4-00075-00006326-00006332": "DRIVER OF THE OTHER VEHICLE DIED, BUT TROOPER MOTSICK", "d1_QrIx_Gj4-00076-00006332-00006549": "DRIVER OF THE OTHER VEHICLE DIED, BUT TROOPER MOTSICK SURVIVED AND CONTINUES TO", "d1_QrIx_Gj4-00077-00006549-00006556": "DIED, BUT TROOPER MOTSICK SURVIVED AND CONTINUES TO", "d1_QrIx_Gj4-00078-00006556-00006736": "DIED, BUT TROOPER MOTSICK SURVIVED AND CONTINUES TO REHABILITATE FROM HIS INJURIES.", "d1_QrIx_Gj4-00079-00006736-00006743": "SURVIVED AND CONTINUES TO REHABILITATE FROM HIS INJURIES.", "d1_QrIx_Gj4-00080-00006743-00006913": "SURVIVED AND CONTINUES TO REHABILITATE FROM HIS INJURIES. FOR THE CRITICAL AND URGENT CARE", "d1_QrIx_Gj4-00081-00006913-00006920": "REHABILITATE FROM HIS INJURIES. FOR THE CRITICAL AND URGENT CARE", "d1_QrIx_Gj4-00082-00006920-00007080": "REHABILITATE FROM HIS INJURIES. FOR THE CRITICAL AND URGENT CARE RENDERED TO TROOPER MOTSICK,", "d1_QrIx_Gj4-00083-00007080-00007087": "FOR THE CRITICAL AND URGENT CARE RENDERED TO TROOPER MOTSICK,", "d1_QrIx_Gj4-00084-00007087-00007223": "FOR THE CRITICAL AND URGENT CARE RENDERED TO TROOPER MOTSICK, FLIGHT MEDIC LINDA ROBERTS AND", "d1_QrIx_Gj4-00085-00007223-00007230": "RENDERED TO TROOPER MOTSICK, FLIGHT MEDIC LINDA ROBERTS AND", "d1_QrIx_Gj4-00086-00007230-00007350": "RENDERED TO TROOPER MOTSICK, FLIGHT MEDIC LINDA ROBERTS AND PARAMEDICS FROM THE RAPID CITY", "d1_QrIx_Gj4-00087-00007350-00007357": "FLIGHT MEDIC LINDA ROBERTS AND PARAMEDICS FROM THE RAPID CITY", "d1_QrIx_Gj4-00088-00007357-00007567": "FLIGHT MEDIC LINDA ROBERTS AND PARAMEDICS FROM THE RAPID CITY FIRE DEPARTMENT WERE AWARDED THE", "d1_QrIx_Gj4-00089-00007567-00007574": "PARAMEDICS FROM THE RAPID CITY FIRE DEPARTMENT WERE AWARDED THE", "d1_QrIx_Gj4-00090-00007574-00007744": "PARAMEDICS FROM THE RAPID CITY FIRE DEPARTMENT WERE AWARDED THE LUKE SCHAULAND MEDAL OF LIFE AND", "d1_QrIx_Gj4-00091-00007744-00007751": "FIRE DEPARTMENT WERE AWARDED THE LUKE SCHAULAND MEDAL OF LIFE AND", "d1_QrIx_Gj4-00092-00007751-00007874": "FIRE DEPARTMENT WERE AWARDED THE LUKE SCHAULAND MEDAL OF LIFE AND DEPUTY JEFF ROBERTS THE"}}, {"audio_id": "d1JpeRH5KZo", "text": {"d1JpeRH5KZo-00000-00001062-00001112": "Hello", "d1JpeRH5KZo-00001-00001144-00001282": "(Laughter)", "d1JpeRH5KZo-00002-00001330-00001482": "This is gonna be easier than I feared", "d1JpeRH5KZo-00003-00001600-00001716": "So, as he's just said...", "d1JpeRH5KZo-00004-00001722-00001846": "...my name is Peter Tennant", "d1JpeRH5KZo-00005-00001900-00002072": "And, I'm another...", "d1JpeRH5KZo-00006-00002170-00002340": "...victim of PhD", "d1JpeRH5KZo-00007-00002340-00002558": "...from Newcastle University", "d1JpeRH5KZo-00008-00002612-00002692": "Or...", "d1JpeRH5KZo-00009-00002732-00002922": "...to use our new international name...", "d1JpeRH5KZo-00010-00002962-00003292": "...The Central University of Newcastle upon Tyne", "d1JpeRH5KZo-00011-00003615-00003770": "I'll give this to our PR team...", "d1JpeRH5KZo-00012-00003770-00004024": "...It's certainly a memorable acronym", "d1JpeRH5KZo-00013-00004052-00004162": "I'm told...", "d1JpeRH5KZo-00014-00004240-00004440": "(Penny drops)", "d1JpeRH5KZo-00015-00005064-00005224": "I thought you guys would be quicker than that", "d1JpeRH5KZo-00016-00005596-00005702": "I'm told...", "d1JpeRH5KZo-00017-00005752-00005858": "...it was chosen...", "d1JpeRH5KZo-00018-00006188-00006368": "OK, someone's in hysterics here...", "d1JpeRH5KZo-00019-00006452-00006656": "I'm told it was chosen specifically...", "d1JpeRH5KZo-00020-00006722-00006842": "...to increase our...", "d1JpeRH5KZo-00021-00006842-00007116": "...visibility amongst international students", "d1JpeRH5KZo-00022-00007290-00007495": "Which on reflection, I guess is cos...", "d1JpeRH5KZo-00023-00007495-00007695": "...student's spend so much time on the internet...", "d1JpeRH5KZo-00024-00007695-00007834": "...searching for such words", "d1JpeRH5KZo-00025-00008040-00008242": "See, that's why I love Newcastle", "d1JpeRH5KZo-00026-00008276-00008526": "Come to a 'thinking person's comedy night'...", "d1JpeRH5KZo-00027-00008598-00008744": "...and you're still guaranteed a laugh...", "d1JpeRH5KZo-00028-00008744-00008866": "...from a cheap cunt-joke", "d1JpeRH5KZo-00029-00009182-00009246": "Which...", "d1JpeRH5KZo-00030-00009330-00009490": "...is just as well really cos...", "d1JpeRH5KZo-00031-00009494-00009812": "...I'm afraid the rest of my material...", "d1JpeRH5KZo-00032-00009860-00009980": "...ain't so good", "d1JpeRH5KZo-00033-00010136-00010264": "You see, unlike Emily...", "d1JpeRH5KZo-00034-00010264-00010464": "...with her pant-pissing Geordies...", "d1JpeRH5KZo-00035-00010788-00010968": "...the content of my research...", "d1JpeRH5KZo-00036-00010996-00011198": "...does not lend itself to comedy", "d1JpeRH5KZo-00037-00011340-00011714": "I actually once applied for a PhD that would've involved...", "d1JpeRH5KZo-00038-00011720-00011906": "...staring down the microscope...", "d1JpeRH5KZo-00039-00011908-00012108": "...At the dissected brains...", "d1JpeRH5KZo-00040-00012108-00012328": "...of a thousand-and-one fruit flies", "d1JpeRH5KZo-00041-00012478-00012634": "Compared with my topic...", "d1JpeRH5KZo-00042-00012634-00012788": "...COMEDY GOLD!", "d1JpeRH5KZo-00043-00012946-00013197": "I would talk to you more generally about my job", "d1JpeRH5KZo-00044-00013256-00013313": "But", "d1JpeRH5KZo-00045-00013416-00013544": "I'm a statistician", "d1JpeRH5KZo-00046-00013652-00013818": "(Jeers)", "d1JpeRH5KZo-00047-00014082-00014290": "That's the reaction I usually get", "d1JpeRH5KZo-00048-00014290-00014504": "I have to say, it's not something I'd usually...", "d1JpeRH5KZo-00049-00014504-00014669": "...want to admit in public", "d1JpeRH5KZo-00050-00014724-00014891": "In fairness to myself...", "d1JpeRH5KZo-00051-00014891-00015200": "...I'm actually something called an Epidemiologist", "d1JpeRH5KZo-00052-00015310-00015597": "(Whoops of knowing recognition)", "d1JpeRH5KZo-00053-00015719-00015913": "No-one has a clue what that means do they?", "d1JpeRH5KZo-00054-00016082-00016213": "Usually when I use it...", "d1JpeRH5KZo-00055-00016213-00016402": "...you do get a blank expression", "d1JpeRH5KZo-00056-00016448-00016682": "It's pretty similar when I say I'm a statistician", "d1JpeRH5KZo-00057-00016716-00016766": "But", "d1JpeRH5KZo-00058-00016846-00016980": "They know what it means...", "d1JpeRH5KZo-00059-00016980-00017164": "...they're just now entirely focussed...", "d1JpeRH5KZo-00060-00017166-00017346": "...on planning their escape", "d1JpeRH5KZo-00061-00017492-00017742": "\"Eeerrrhhh, so a statistician\"", "d1JpeRH5KZo-00062-00017798-00017876": "\"Right\"", "d1JpeRH5KZo-00063-00017938-00018232": "\"I just realised my tie's on the wrong way round, so...\"", "d1JpeRH5KZo-00064-00018302-00018352": "Great!", "d1JpeRH5KZo-00065-00018354-00018414": "Yeah!", "d1JpeRH5KZo-00066-00018770-00018938": "With 'Epidemiology'...", "d1JpeRH5KZo-00067-00019014-00019158": "...it's genuine gormless", "d1JpeRH5KZo-00068-00019296-00019378": "Usually...", "d1JpeRH5KZo-00069-00019378-00019678": "...disguised by one of those fake, knowing nods", "d1JpeRH5KZo-00070-00019850-00019954": "\"Interesting\"", "d1JpeRH5KZo-00071-00020188-00020444": "You have no idea what that means do you?", "d1JpeRH5KZo-00072-00020518-00020710": "\"No... Erm...\"", "d1JpeRH5KZo-00073-00020710-00020888": "\"Skin, right?\"", "d1JpeRH5KZo-00074-00020914-00021170": "No it is not to do with the fucking skin!", "d1JpeRH5KZo-00075-00021328-00021558": "Dermatology is the study of skin", "d1JpeRH5KZo-00076-00021616-00021810": "Sometimes I think it would probably be easier...", "d1JpeRH5KZo-00077-00021818-00021946": "...to retrain as a dermatologist", "d1JpeRH5KZo-00078-00022032-00022244": "Than to keep having to explain to everyone that...", "d1JpeRH5KZo-00079-00022244-00022294": "No", "d1JpeRH5KZo-00080-00022306-00022356": "Alas", "d1JpeRH5KZo-00081-00022356-00022628": "...I'm afraid I don't know the best way to get rid of cellulite", "d1JpeRH5KZo-00082-00023348-00023398": "(So)", "d1JpeRH5KZo-00083-00023562-00023848": "When I'm asked to describe Epidemiology...", "d1JpeRH5KZo-00084-00023890-00023976": "I usually say...", "d1JpeRH5KZo-00085-00023976-00024176": "...it's like being a detective", "d1JpeRH5KZo-00086-00024262-00024386": "I'm lying of course", "d1JpeRH5KZo-00087-00024506-00024818": "But it briefly makes me feel cool and important...", "d1JpeRH5KZo-00088-00024872-00025024": "...instead of a massive geek", "d1JpeRH5KZo-00089-00025084-00025408": "You see, Epidemiology sits rather awkwardly between...", "d1JpeRH5KZo-00090-00025408-00025608": "...the hard sciences like Biology", "d1JpeRH5KZo-00091-00025639-00025712": "(Lone whoop)", "d1JpeRH5KZo-00092-00025718-00025814": "And, Erm...", "d1JpeRH5KZo-00093-00026088-00026248": "And, the other stuff", "d1JpeRH5KZo-00094-00026248-00026544": "The pant-pissing stuff we heard about earlier", "d1JpeRH5KZo-00095-00026600-00026650": "(Erm)", "d1JpeRH5KZo-00096-00026770-00026820": "So", "d1JpeRH5KZo-00097-00026820-00027020": "At the far end of biomedical research...", "d1JpeRH5KZo-00098-00027020-00027180": "...you have the Biologists", "d1JpeRH5KZo-00099-00027208-00027432": "Who spend their time creating...", "d1JpeRH5KZo-00100-00027448-00027648": "TERRIFYING MUTANT RATS!", "d1JpeRH5KZo-00101-00028100-00028262": "I may have sexed that up a little bit", "d1JpeRH5KZo-00102-00028300-00028368": "But in fairness...", "d1JpeRH5KZo-00103-00028368-00028674": "...these people spend their time looking at dissected fly brains", "d1JpeRH5KZo-00104-00028677-00028876": "So you gotta give me a little bit of room...", "d1JpeRH5KZo-00105-00028877-00029077": "...For artistic licence", "d1JpeRH5KZo-00106-00029094-00029230": "So next step down...", "d1JpeRH5KZo-00107-00029238-00029412": "...you have the clinical trials", "d1JpeRH5KZo-00108-00029412-00029633": "Which are quite similar actually", "d1JpeRH5KZo-00109-00029686-00029736": "(Er)", "d1JpeRH5KZo-00110-00029768-00029839": "Hopefully", "d1JpeRH5KZo-00111-00029850-00029914": "Th-than rats", "d1JpeRH5KZo-00112-00030008-00030352": "Hopefully, our participants are not quite as hairy", "d1JpeRH5KZo-00113-00030438-00030550": "Though, I have to say...", "d1JpeRH5KZo-00114-00030550-00030702": "...towards the end of Movember...", "d1JpeRH5KZo-00115-00030702-00030912": "...It can be difficult to tell the difference", "d1JpeRH5KZo-00116-00031074-00031418": "One of the problems you have with working with people...", "d1JpeRH5KZo-00117-00031572-00031670": "...Is ethics", "d1JpeRH5KZo-00118-00031722-00031952": "Which stops you putting everyone in cages", "d1JpeRH5KZo-00119-00032150-00032200": "So...", "d1JpeRH5KZo-00120-00032268-00032500": "But usually as long as you start with two groups...", "d1JpeRH5KZo-00121-00032500-00032680": "...that are fairly similar to begin with...", "d1JpeRH5KZo-00122-00032680-00032854": "...then things should be all right", "d1JpeRH5KZo-00123-00032918-00033070": "With Epidemiology...", "d1JpeRH5KZo-00124-00033102-00033364": "We don't have the luxury of controlling people like that", "d1JpeRH5KZo-00125-00033364-00033646": "We just have to observe them in their natural habitat", "d1JpeRH5KZo-00126-00033808-00034064": "So, let's say we're looking at coffee", "d1JpeRH5KZo-00127-00034068-00034216": "We can't get a hundred people", "d1JpeRH5KZo-00128-00034310-00034694": "Give fifty of them unlimited access to delicious cappuccino", "d1JpeRH5KZo-00129-00034764-00034958": "And then the other fifty have to have some kind of control", "d1JpeRH5KZo-00130-00034958-00035024": "Like...", "d1JpeRH5KZo-00131-00035030-00035140": "...celery juice", "d1JpeRH5KZo-00132-00035298-00035498": "Interesting as that may sound", "d1JpeRH5KZo-00133-00035596-00035700": "Especially...", "d1JpeRH5KZo-00134-00035776-00035976": "...if you can then put them all in a cage...", "d1JpeRH5KZo-00135-00035976-00036116": "...With a coffee cup in the middle...", "d1JpeRH5KZo-00136-00036116-00036316": "...and watch them fight it out", "d1JpeRH5KZo-00137-00036462-00036534": "Alas", "d1JpeRH5KZo-00138-00036580-00036656": "Ethics", "d1JpeRH5KZo-00139-00036708-00036956": "So, that's where statistics comes in", "d1JpeRH5KZo-00140-00037006-00037230": "It's basically like a large magic wand", "d1JpeRH5KZo-00141-00037338-00037644": "Actually, it's more like a really boring calculator...", "d1JpeRH5KZo-00142-00037644-00037836": "...where you can't even amuse yourself...", "d1JpeRH5KZo-00143-00037836-00038064": "...by making rude words out of upside-down numbers", "d1JpeRH5KZo-00144-00038388-00038450": "And...", "d1JpeRH5KZo-00145-00038450-00038564": "...the truth is...", "d1JpeRH5KZo-00146-00038564-00038728": "...the power of statistics...", "d1JpeRH5KZo-00147-00038728-00038928": "...has been greatly exaggerated", "d1JpeRH5KZo-00148-00039034-00039162": "I have to say for me personally...", "d1JpeRH5KZo-00149-00039162-00039360": "...one of the most annoying things...", "d1JpeRH5KZo-00150-00039404-00039620": "...about being a statistician is people saying to me", "d1JpeRH5KZo-00151-00039674-00039984": "\"Aaah, you can use statistics to prove anything\"", "d1JpeRH5KZo-00152-00040120-00040280": "One tiny little myth", "d1JpeRH5KZo-00153-00040348-00040620": "And I'm basically a permanent source of disappointment", "d1JpeRH5KZo-00154-00040814-00041046": "So... Back to my research topic", "d1JpeRH5KZo-00155-00041164-00041556": "Not something I would usually talk about in polite company", "d1JpeRH5KZo-00156-00041566-00041642": "Although actually...", "d1JpeRH5KZo-00157-00041642-00041798": "...from what I've seen from you guys this evening...", "d1JpeRH5KZo-00158-00041798-00041988": "...I guess I'm OK, so", "d1JpeRH5KZo-00159-00042098-00042194": "I'll give you a clue...", "d1JpeRH5KZo-00160-00042194-00042298": "...it's to do with pregnancy", "d1JpeRH5KZo-00161-00042340-00042482": "Obesity in pregnancy, actually", "d1JpeRH5KZo-00162-00042482-00042654": "At this stage I was tempted...", "d1JpeRH5KZo-00163-00042654-00042854": "...To make a bunch of fat pregnant jokes", "d1JpeRH5KZo-00164-00042930-00043044": "But at some point in the future...", "d1JpeRH5KZo-00165-00043044-00043274": "...I would also like to be able to obtain funding", "d1JpeRH5KZo-00166-00043394-00043628": "Those options are out", "d1JpeRH5KZo-00167-00043724-00043804": "Besides...", "d1JpeRH5KZo-00168-00043828-00044124": "Pregnant women have already had it hard enough", "d1JpeRH5KZo-00169-00044386-00044670": "(Applause)", "d1JpeRH5KZo-00170-00045138-00045380": "Newcastle, I knew you wouldn't let me down", "d1JpeRH5KZo-00171-00045814-00046198": "Has anyone seen the list of things that pregnant women are advised to avoid?", "d1JpeRH5KZo-00172-00046306-00046378": "Clingfilm", "d1JpeRH5KZo-00173-00046406-00046478": "Shampoo", "d1JpeRH5KZo-00174-00046578-00046658": "Frying pans", "d1JpeRH5KZo-00175-00046856-00047144": "Admittedly, that last one - to me - seemed a little bit obvious", "d1JpeRH5KZo-00176-00047192-00047420": "But I guess if you've never been whacked in the face by one", "d1JpeRH5KZo-00177-00047774-00047972": "So, obesity in pregnancy...", "d1JpeRH5KZo-00178-00047972-00048112": "That's my...", "d1JpeRH5KZo-00179-00048112-00048286": "...that's my risk-factor", "d1JpeRH5KZo-00180-00048334-00048414": "The outcome", "d1JpeRH5KZo-00181-00048520-00048768": "Not something I'd usually talk about", "d1JpeRH5KZo-00182-00048862-00048918": "However", "d1JpeRH5KZo-00183-00048918-00049310": "...it can occasionally have its uses in impolite company", "d1JpeRH5KZo-00184-00049436-00049570": "I once had a ride...", "d1JpeRH5KZo-00185-00049570-00049732": "...I recently had a ride with...", "d1JpeRH5KZo-00186-00049732-00050036": "...One of those really annoying taxi drivers", "d1JpeRH5KZo-00187-00050110-00050236": "You know, the ones who just talk?", "d1JpeRH5KZo-00188-00050700-00050750": "And", "d1JpeRH5KZo-00189-00050830-00050992": "For some reason he doesn't like students", "d1JpeRH5KZo-00190-00051074-00051244": "And he wasn't afraid to say it", "d1JpeRH5KZo-00191-00051344-00051508": "So, I'm sat in the back of his car...", "d1JpeRH5KZo-00192-00051566-00051726": "...and he turns to me and he says,", "d1JpeRH5KZo-00193-00051802-00051978": "\"I fuckin' hate students\"", "d1JpeRH5KZo-00194-00052104-00052304": "\"I just wanna run 'em all down\"", "d1JpeRH5KZo-00195-00052641-00052754": "It was a bit wierd", "d1JpeRH5KZo-00196-00052832-00052996": "...I was obviously a student", "d1JpeRH5KZo-00197-00053074-00053232": "I like to think in that light...", "d1JpeRH5KZo-00198-00053232-00053404": "...possibly even an undergraduate", "d1JpeRH5KZo-00199-00054146-00054290": "Anyway, he continued", "d1JpeRH5KZo-00200-00054322-00054590": "\"Why don't they just go out and get a proper fuckin' job?\"", "d1JpeRH5KZo-00201-00054590-00054734": "\"What do you do anyway?\"", "d1JpeRH5KZo-00202-00055182-00055286": "First instinct", "d1JpeRH5KZo-00203-00055340-00055467": "I'm a statistician", "d1JpeRH5KZo-00204-00055626-00055712": "If he kept talking...", "d1JpeRH5KZo-00205-00055712-00055860": "...I could then bombard him with...", "d1JpeRH5KZo-00206-00055860-00056184": "...fascinating stories about probability distributions", "d1JpeRH5KZo-00207-00056372-00056448": "But on this occasion...", "d1JpeRH5KZo-00208-00056562-00056714": "...I thought I'd bring out the big guns", "d1JpeRH5KZo-00209-00057028-00057196": "So, I composed myself...", "d1JpeRH5KZo-00210-00057394-00057500": "...took a deep breath...", "d1JpeRH5KZo-00211-00057676-00057754": "I said", "d1JpeRH5KZo-00212-00057870-00057926": "Who?", "d1JpeRH5KZo-00213-00057960-00058020": "Me?!", "d1JpeRH5KZo-00214-00058102-00058170": "Well...", "d1JpeRH5KZo-00215-00058170-00058284": "...I study the causes of...", "d1JpeRH5KZo-00216-00058284-00058484": "...stillbirth and infant death", "d1JpeRH5KZo-00217-00058882-00059028": "He didn't say another word", "d1JpeRH5KZo-00218-00059390-00059598": "Thank you very much ladies and gentleman", "d1JpeRH5KZo-00219-00060362-00060696": "(You've been a very) generous audience", "d1JpeRH5KZo-00220-00060702-00060934": "If anyone has any questions about statistics...", "d1JpeRH5KZo-00221-00061052-00061176": "...please don't ask me", "d1JpeRH5KZo-00222-00061278-00061505": "That's why God invented the internet", "d1JpeRH5KZo-00223-00061644-00061798": "Well, that and...", "d1JpeRH5KZo-00224-00061840-00061941": "Searching for pictures of...", "d1JpeRH5KZo-00225-00061941-00062172": "...the Central University of Newcastle upon Tyne"}}, {"audio_id": "d1LV3QKosQu", "text": {"d1LV3QKosQu-00000-00000000-00000200": "RTX 3080 vs RTX 3090 vs RTX 4080 RDR 2"}}, {"audio_id": "d1QzEjgI7Fg", "text": {"d1QzEjgI7Fg-00000-00000012-00000137": "- Hey, guys, my name is Jordan,", "d1QzEjgI7Fg-00001-00000137-00000309": "and right now I have two legs,", "d1QzEjgI7Fg-00002-00000309-00000561": "but in a few months I may only have one.", "d1QzEjgI7Fg-00003-00000561-00000802": "I am actively in the process of trying to decide", "d1QzEjgI7Fg-00004-00000802-00000986": "what the best option for my future is,", "d1QzEjgI7Fg-00005-00000986-00001259": "and I may be having my leg amputated", "d1QzEjgI7Fg-00006-00001259-00001583": "in a few months, and that is a weird sentence.", "d1QzEjgI7Fg-00007-00001583-00001826": "I don't think it's actually sunk in just yet,", "d1QzEjgI7Fg-00008-00001826-00001968": "and so I am recording this video", "d1QzEjgI7Fg-00009-00001968-00002468": "to start my journey, and if I do decide", "d1QzEjgI7Fg-00010-00002577-00002793": "to have this leg amputation, I will probably", "d1QzEjgI7Fg-00011-00002793-00003062": "start publishing these videos as part of", "d1QzEjgI7Fg-00012-00003062-00003395": "sort of my journey of healing, because I have found it", "d1QzEjgI7Fg-00013-00003395-00003721": "really healing to me with other issues", "d1QzEjgI7Fg-00014-00003721-00003922": "in my life to talk to a camera.", "d1QzEjgI7Fg-00015-00003922-00004118": "It helps me process through things,", "d1QzEjgI7Fg-00016-00004118-00004305": "and I have found it really helpful", "d1QzEjgI7Fg-00017-00004305-00004434": "to hear other people's journeys,", "d1QzEjgI7Fg-00018-00004434-00004841": "other people's stories, and so today is September 4, 2018,", "d1QzEjgI7Fg-00019-00004958-00005184": "and I'm just gonna start talking about my process", "d1QzEjgI7Fg-00020-00005184-00005505": "in hopes that it will help me work through things", "d1QzEjgI7Fg-00021-00005505-00005684": "and help someone else maybe somewhere.", "d1QzEjgI7Fg-00022-00005684-00005976": "So a little bit about my story.", "d1QzEjgI7Fg-00023-00005976-00006274": "I had a really bad horseback riding accident when I was 13.", "d1QzEjgI7Fg-00024-00006274-00006470": "I am now 27.", "d1QzEjgI7Fg-00025-00006470-00006598": "During that horseback riding accident,", "d1QzEjgI7Fg-00026-00006598-00006909": "I shattered my ankle in a way that had orthopedic surgeons", "d1QzEjgI7Fg-00027-00006909-00007106": "going gosh, we've never seen this before.", "d1QzEjgI7Fg-00028-00007106-00007302": "It's never a good thing to excite surgeons.", "d1QzEjgI7Fg-00029-00007302-00007641": "And I had a surgery then, and then I had surgery", "d1QzEjgI7Fg-00030-00007641-00007819": "two months later when they had to re-break my ankle", "d1QzEjgI7Fg-00031-00007819-00007923": "'cause it healed wrong.", "d1QzEjgI7Fg-00032-00007923-00008211": "Then I had an ankle fusion in '15.", "d1QzEjgI7Fg-00033-00008211-00008317": "I had surgery after that.", "d1QzEjgI7Fg-00034-00008317-00008530": "I have had surgery after surgery after surgery,", "d1QzEjgI7Fg-00035-00008530-00008683": "trying to piece my ankle back together", "d1QzEjgI7Fg-00036-00008683-00008822": "and get it to stop hurting.", "d1QzEjgI7Fg-00037-00008822-00008985": "It's never really stopped hurting.", "d1QzEjgI7Fg-00038-00008985-00009127": "Now for a few years it got to a place", "d1QzEjgI7Fg-00039-00009127-00009434": "where I could really function, and I could go hiking", "d1QzEjgI7Fg-00040-00009434-00009708": "and horseback riding, and I did MMA for two years,", "d1QzEjgI7Fg-00041-00009708-00009891": "and I was competitive in jujitsu.", "d1QzEjgI7Fg-00042-00009891-00010037": "And that is a fine life.", "d1QzEjgI7Fg-00043-00010037-00010219": "Like it hurt, it was annoying, who cares?", "d1QzEjgI7Fg-00044-00010219-00010397": "Like that was fine by me.", "d1QzEjgI7Fg-00045-00010397-00010565": "But now things have progressed to a place", "d1QzEjgI7Fg-00046-00010565-00010974": "over the last year and half where I cannot do anything", "d1QzEjgI7Fg-00047-00010974-00011317": "except like walk from, like walk around my house", "d1QzEjgI7Fg-00048-00011317-00011661": "and walk from my car to a building and back,", "d1QzEjgI7Fg-00049-00011661-00011804": "and even then it really hurts,", "d1QzEjgI7Fg-00050-00011804-00011983": "and I'm limping constantly, and I'm in pain", "d1QzEjgI7Fg-00051-00011983-00012238": "when I'm sitting still, and it will not stop hurting,", "d1QzEjgI7Fg-00052-00012238-00012477": "and I cannot do anything.", "d1QzEjgI7Fg-00053-00012477-00012691": "I can't do anything that I love,", "d1QzEjgI7Fg-00054-00012691-00012987": "and I can barely walk, and so I was told", "d1QzEjgI7Fg-00055-00012987-00013203": "in my most recent surgery in March", "d1QzEjgI7Fg-00056-00013203-00013557": "that essentially I have no options left.", "d1QzEjgI7Fg-00057-00013557-00013772": "Like after the surgery, a few months later", "d1QzEjgI7Fg-00058-00013772-00013919": "at the follow-up appointment, my surgeon", "d1QzEjgI7Fg-00059-00013919-00014057": "walked into the room and was basically like,", "d1QzEjgI7Fg-00060-00014057-00014140": "how's it feeling?", "d1QzEjgI7Fg-00061-00014140-00014246": "And I was like, well, it still sucks.", "d1QzEjgI7Fg-00062-00014246-00014385": "And he was like, oh, okay, well,", "d1QzEjgI7Fg-00063-00014385-00014603": "you have no options left; bye.", "d1QzEjgI7Fg-00064-00014603-00014754": "That was basically our conversation,", "d1QzEjgI7Fg-00065-00014754-00014882": "and so I was really discouraged,", "d1QzEjgI7Fg-00066-00014882-00015143": "but I thought, you know what, that does not work for me.", "d1QzEjgI7Fg-00067-00015143-00015258": "And so I did a lot of research", "d1QzEjgI7Fg-00068-00015258-00015387": "and I found a surgeon up in Denver", "d1QzEjgI7Fg-00069-00015387-00015676": "who is very highly respected in his field,", "d1QzEjgI7Fg-00070-00015676-00015929": "and I met with him a couple weeks ago with my husband,", "d1QzEjgI7Fg-00071-00015929-00016268": "and he suggested another option, which is a little risky,", "d1QzEjgI7Fg-00072-00016268-00016544": "but he said we could do an ankle fusion", "d1QzEjgI7Fg-00073-00016544-00016779": "of the subtalar joint, which is,", "d1QzEjgI7Fg-00074-00016779-00016862": "you have your ankle joint,", "d1QzEjgI7Fg-00075-00016862-00016973": "then you have your subtalar joint.", "d1QzEjgI7Fg-00076-00016973-00017230": "My ankle joint is fused so it doesn't exist anymore.", "d1QzEjgI7Fg-00077-00017230-00017535": "I'm gonna confuse the subtalar joint and replace my ankle.", "d1QzEjgI7Fg-00078-00017535-00017811": "So I had an ankle replacement in that fusion.", "d1QzEjgI7Fg-00079-00017811-00017989": "The problem is there are no studies", "d1QzEjgI7Fg-00080-00017989-00018167": "on how well that actually works.", "d1QzEjgI7Fg-00081-00018167-00018419": "Because I have had over 10 surgeries in my life,", "d1QzEjgI7Fg-00082-00018419-00018598": "it's just messed up in there.", "d1QzEjgI7Fg-00083-00018598-00018961": "The ankle is not a big joint, and it's constantly swollen.", "d1QzEjgI7Fg-00084-00018961-00019151": "There's a ton of nerve damage in there,", "d1QzEjgI7Fg-00085-00019151-00019452": "and going in there and doing that severe of a surgery,", "d1QzEjgI7Fg-00086-00019604-00019893": "they don't know that it would actually help,", "d1QzEjgI7Fg-00087-00019893-00020197": "and it would be significant surgery", "d1QzEjgI7Fg-00088-00020197-00020415": "with a lot of recovery time and learning to walk again,", "d1QzEjgI7Fg-00089-00020415-00020640": "'cause I haven't had any goal-draining years,", "d1QzEjgI7Fg-00090-00020753-00021179": "and might just get me sort of walking", "d1QzEjgI7Fg-00091-00021179-00021430": "for a few years if it worked,", "d1QzEjgI7Fg-00092-00021430-00021662": "and then I would have to have like amputation anyway.", "d1QzEjgI7Fg-00093-00021662-00022026": "So right now where I am, I've been dealing with this", "d1QzEjgI7Fg-00094-00022026-00022136": "for over half of my life.", "d1QzEjgI7Fg-00095-00022136-00022364": "I have been having surgery after surgery after surgery", "d1QzEjgI7Fg-00096-00022364-00022611": "for half my life, trying to save a piece of my body", "d1QzEjgI7Fg-00097-00022611-00022929": "that hurts constantly, and I am wondering", "d1QzEjgI7Fg-00098-00022929-00023365": "if the best option isn't just to admit where it is,", "d1QzEjgI7Fg-00099-00023365-00023694": "and if the fastest way to a life", "d1QzEjgI7Fg-00100-00023694-00023881": "that I actually get to live", "d1QzEjgI7Fg-00101-00023881-00024145": "is not just to have it amputated.", "d1QzEjgI7Fg-00102-00024145-00024356": "And I know that probably sound bizarre to people,", "d1QzEjgI7Fg-00103-00024356-00024525": "and I know that a lot of people will probably comment", "d1QzEjgI7Fg-00104-00024525-00024817": "that I'm insane or ungrateful, and I'm not.", "d1QzEjgI7Fg-00105-00024817-00024936": "I'm really grateful for the fact", "d1QzEjgI7Fg-00106-00024936-00025124": "that I have two legs and that I can walk,", "d1QzEjgI7Fg-00107-00025124-00025376": "but every, it hurts all the time,", "d1QzEjgI7Fg-00108-00025376-00025593": "and it's affecting other joints in my body.", "d1QzEjgI7Fg-00109-00025593-00025808": "I have neck pain constantly, in part because of it.", "d1QzEjgI7Fg-00110-00025808-00026008": "My knee is getting messed up because I walk differently", "d1QzEjgI7Fg-00111-00026008-00026464": "because of it, and I'm young and otherwise healthy,", "d1QzEjgI7Fg-00112-00026464-00026576": "and I don't have kids right now,", "d1QzEjgI7Fg-00113-00026576-00026698": "and I have a great support system,", "d1QzEjgI7Fg-00114-00026698-00027164": "so it makes sense to me to have a leg amputation now", "d1QzEjgI7Fg-00115-00027164-00027342": "below the knee, like amputation,", "d1QzEjgI7Fg-00116-00027342-00027608": "I should clarify that, instead of later.", "d1QzEjgI7Fg-00117-00027608-00027786": "And some people think I'm nuts for that.", "d1QzEjgI7Fg-00118-00027786-00028043": "But I'm meeting with the doctor on September 13th,", "d1QzEjgI7Fg-00119-00028043-00028377": "so in just a few days, to discuss options", "d1QzEjgI7Fg-00120-00028377-00028722": "and see where things go, but I've been talking", "d1QzEjgI7Fg-00121-00028722-00029004": "to the amputee community, which has been amazing,", "d1QzEjgI7Fg-00122-00029004-00029176": "because there are a surprising number of people", "d1QzEjgI7Fg-00123-00029176-00029407": "who have leg amputations when you really start", "d1QzEjgI7Fg-00124-00029407-00029686": "talking to people, and there's been a lot of support", "d1QzEjgI7Fg-00125-00029686-00029847": "and a lot of answering questions,", "d1QzEjgI7Fg-00126-00029847-00030027": "and a lot of telling me to ask questions", "d1QzEjgI7Fg-00127-00030027-00030161": "I wouldn't have even thought to ask.", "d1QzEjgI7Fg-00128-00030161-00030661": "And I don't know how to feel about all of this.", "d1QzEjgI7Fg-00129-00030742-00030995": "I think for a lot of people, losing a limb", "d1QzEjgI7Fg-00130-00030995-00031164": "sounds like the worst thing in the world,", "d1QzEjgI7Fg-00131-00031164-00031533": "and to me it doesn't right now,", "d1QzEjgI7Fg-00132-00031533-00031691": "but I think I'm just thinking about things", "d1QzEjgI7Fg-00133-00031691-00031887": "from like a rational perspective.", "d1QzEjgI7Fg-00134-00031887-00032014": "Like it makes sense to do this,", "d1QzEjgI7Fg-00135-00032014-00032317": "because it's the quickest way to a better life.", "d1QzEjgI7Fg-00136-00032402-00032780": "But I don't know how to measure the emotional impact of it,", "d1QzEjgI7Fg-00137-00032780-00032897": "the emotional impact of being", "d1QzEjgI7Fg-00138-00032897-00033092": "a 27 year old girl with no leg.", "d1QzEjgI7Fg-00139-00033321-00033418": "So that's weird.", "d1QzEjgI7Fg-00140-00033552-00033817": "But I guess we'll just see how it goes.", "d1QzEjgI7Fg-00141-00033817-00033969": "We'll see what happens.", "d1QzEjgI7Fg-00142-00033969-00034123": "But I want to be active.", "d1QzEjgI7Fg-00143-00034123-00034270": "I want to be able to run again.", "d1QzEjgI7Fg-00144-00034270-00034675": "I haven't been able to do that since I was a little kid.", "d1QzEjgI7Fg-00145-00034675-00035036": "And I hope that that is an option.", "d1QzEjgI7Fg-00146-00035036-00035196": "I hope that's something that I can do,", "d1QzEjgI7Fg-00147-00035196-00035696": "and this is all kind of freaky and scary", "d1QzEjgI7Fg-00148-00035833-00035959": "and frightening to think about,", "d1QzEjgI7Fg-00149-00035959-00036186": "but part of me is also excited", "d1QzEjgI7Fg-00150-00036186-00036505": "at the possibility of maybe in two years,", "d1QzEjgI7Fg-00151-00036505-00036847": "like after the recovery is mostly done,", "d1QzEjgI7Fg-00152-00036847-00037075": "like being able to run and being able to do stuff,", "d1QzEjgI7Fg-00153-00037075-00037264": "and being alive with my dogs, and even just", "d1QzEjgI7Fg-00154-00037264-00037457": "fricking walk around the block", "d1QzEjgI7Fg-00155-00037457-00037645": "without as much pain as I have right now.", "d1QzEjgI7Fg-00156-00037645-00037938": "So that's where I am, and that's where", "d1QzEjgI7Fg-00157-00037938-00038104": "my thought process is currently.", "d1QzEjgI7Fg-00158-00038104-00038495": "I'm sure it will fluctuate, but thanks for listening.", "d1QzEjgI7Fg-00159-00038495-00038711": "I don't know if you, personally,", "d1QzEjgI7Fg-00160-00038711-00038895": "are dealing with an amputation,", "d1QzEjgI7Fg-00161-00038895-00039016": "thinking about it, know someone,", "d1QzEjgI7Fg-00162-00039016-00039313": "whatever it is, but I just want to share my thoughts", "d1QzEjgI7Fg-00163-00039313-00039450": "on where I am right now", "d1QzEjgI7Fg-00164-00039450-00039642": "and what my story looks like at this point.", "d1QzEjgI7Fg-00165-00039642-00039725": "Thanks, guys.", "d1QzEjgI7Fg-00166-00039725-00039863": "I will talk to you soon.", "d1QzEjgI7Fg-00167-00039863-00040023": "I appreciate you listening; bye."}}, {"audio_id": "d2xKYeMC7fc", "text": {"d2xKYeMC7fc-00000-00000165-00000489": "Hi my loves. Chantal Heide, Canada's dating coach.", "d2xKYeMC7fc-00001-00000543-00000918": "And I want to send a shout out to all my readers", "d2xKYeMC7fc-00002-00000964-00001602": "I need you! I need you to go on Amazon and go leave your review.", "d2xKYeMC7fc-00003-00001639-00002436": "I get so many emails, messages, comments from those of you who have read my books.", "d2xKYeMC7fc-00004-00002459-00003022": "I get the most beautiful messages and I'd love to take this", "d2xKYeMC7fc-00005-00003027-00003533": "and pay it forward so that other people can learn the lessons that you've learned", "d2xKYeMC7fc-00006-00003561-00003862": "and improve their lives the way you've improved yours", "d2xKYeMC7fc-00007-00003925-00004306": "and lean into what I teach because you and I both know", "d2xKYeMC7fc-00008-00004340-00004658": "that it can take you to a whole new level when it comes to love.", "d2xKYeMC7fc-00009-00004685-00005020": "So if you read one of my book, you enjoyed what you read,", "d2xKYeMC7fc-00010-00005038-00005554": "please go on amazon, amazon.com, amazon.ca... wherever!", "d2xKYeMC7fc-00011-00005573-00006051": "and go leave your review; whatever it was that you thought, whatever it was that you learned", "d2xKYeMC7fc-00012-00006056-00006316": "even if you leave five starts and go 'liked it'", "d2xKYeMC7fc-00013-00006358-00006776": "It doesn't matter. What this is going to do is this is going to encourage people", "d2xKYeMC7fc-00014-00006817-00007032": "to pick up a copy themselves.", "d2xKYeMC7fc-00015-00007056-00007448": "Read that book, like I say stick it by the toilet if you don't have time", "d2xKYeMC7fc-00016-00007453-00007700": "you'll finish a chapter every time you sit down", "d2xKYeMC7fc-00017-00007766-00008137": "and hopefully it will open their hearts like it opened yours.", "d2xKYeMC7fc-00018-00008159-00008569": "So, again, please... go leave your review on Amazon.", "d2xKYeMC7fc-00019-00008589-00008788": "Thank you, guys. I love you. Bye!"}}, {"audio_id": "d2I3BzNR6eM", "text": {"d2I3BzNR6eM-00000-00000003-00000203": "- Hello! What's your name and where are you from?", "d2I3BzNR6eM-00001-00000203-00000533": "Hi, my name is Mauhing Yip. I'm from Norway.", "d2I3BzNR6eM-00002-00000533-00001200": "I'm also a Master student of physics from Norwegian University of Natural Science and Technology.", "d2I3BzNR6eM-00003-00001200-00001393": "And what brings you to the UK?", "d2I3BzNR6eM-00004-00001393-00002580": "I joined the programme called HPC-Europa. They gave me the supercomputer access at the EPCC at Edinburgh.", "d2I3BzNR6eM-00005-00002580-00003193": "They also cover all theaccommodation and travel.", "d2I3BzNR6eM-00006-00003193-00004706": "After Edinburgh I willvisit Dr. Colin Cotter at Imperial College withHPC-Europa funding all the travel.", "d2I3BzNR6eM-00007-00004706-00005003": "And what are you going toresearch while you're here?", "d2I3BzNR6eM-00008-00005003-00005683": "I research particle diffusionin the water in the ocean environment.", "d2I3BzNR6eM-00009-00005683-00006503": "My goal isto give a correct model to estimate the particle, how it diffuses in the ocean.", "d2I3BzNR6eM-00010-00006503-00006703": "What are these particles?", "d2I3BzNR6eM-00011-00006703-00007246": "This particle could be microplastic I think it will be the bigger bigger issue to the whole one;", "d2I3BzNR6eM-00012-00007246-00007734": "it could also be the fish eggs;it could also be the oil jobs.", "d2I3BzNR6eM-00013-00007734-00008103": "And do you need HPC - supercomputing - for that?", "d2I3BzNR6eM-00014-00008103-00009243": "Yes, to simulate such process I need to launch a lot, a lot of particles. It takes a lifetime to do them in a personal computer", "d2I3BzNR6eM-00015-00009243-00010356": "so I need the supercomputer to run the program in parallel and it would be most efficient and much, much faster.", "d2I3BzNR6eM-00016-00010356-00010603": "OK, thank you very much.", "d2I3BzNR6eM-00017-00010603-00010785": "You're welcome, thank you."}}, {"audio_id": "d303SVgbBfg", "text": {"d303SVgbBfg-00000-00000973-00002452": "I still have 9!!!!"}}, {"audio_id": "d3ou5iuZlyA", "text": {"d3ou5iuZlyA-00000-00000400-00000730": "Hello. This is the eighth session of ‘Dr. Tomato Protocol’.", "d3ou5iuZlyA-00001-00000730-00001301": "Today I will be explaining stage two of the three stages of autism development,", "d3ou5iuZlyA-00002-00001301-00001485": "fixation, and the vicious cycle that follows.", "d3ou5iuZlyA-00003-00001485-00001837": "I have previously explained that stage two is the ‘autism fixation stage’.", "d3ou5iuZlyA-00004-00001837-00002387": "* The causes of exacerbation and fixation of autism are SIBO symptoms and autoimmune damage of the central nervous system.", "d3ou5iuZlyA-00005-00002387-00002790": "What is the thing all of you must understand before today’s session?", "d3ou5iuZlyA-00006-00002790-00003332": "It is that the fixation process is the progression of ‘irreversable cranial nerve damage’.", "d3ou5iuZlyA-00007-00003332-00003570": "What does ‘irreversable damage’ mean?", "d3ou5iuZlyA-00008-00003570-00003899": "That any damage made during progression does not get recovered easily.", "d3ou5iuZlyA-00009-00003899-00004220": "What happenes after irreversable brain damage?", "d3ou5iuZlyA-00010-00004220-00004566": "Cognitive decline. The process of declining intelligence.", "d3ou5iuZlyA-00011-00004566-00005071": "I do not think that kids with autism spectrum disorder have low intelligence from birth.", "d3ou5iuZlyA-00012-00005071-00005446": "This is because most kids at the begining stages, stage 1 in other words,", "d3ou5iuZlyA-00013-00005446-00005814": "show normal recognition after treatments even when they showed severe sensory process disorder,", "d3ou5iuZlyA-00014-00005814-00006784": "visual processing, auditory processing, and sleeping disorders and looked like they had severe autism.", "d3ou5iuZlyA-00015-00006784-00007150": "However, kids that went through stage two damage process for a long time", "d3ou5iuZlyA-00016-00007150-00007500": "take much longer to recover their recognition even after treatment", "d3ou5iuZlyA-00017-00007500-00007913": "In some cases they don’t recover at all.", "d3ou5iuZlyA-00018-00007913-00008740": "Therefore, recieving treatment before deep and long irreversable brain damage takes place would be the most crucial and essential part of autism treatment.", "d3ou5iuZlyA-00019-00008740-00009032": "Why does autism rapidly progresses and deterioates?", "d3ou5iuZlyA-00020-00009032-00009287": "You have to understand that STBO is the fundamental reason.", "d3ou5iuZlyA-00021-00009287-00009723": "What does SIBO mean? It means ‘Overgrowth of bacteria in the small intestine’.", "d3ou5iuZlyA-00022-00009723-00009872": "Saying that the abnormality in the intestinal flora,", "d3ou5iuZlyA-00023-00009872-00010726": "that is, the dysbiosis state in which the microbiome is unstable, is the cause of autism may be good enough as a concept.", "d3ou5iuZlyA-00024-00010726-00011267": "However, thinking this as a concept of ‘fewer beneficial bacteria and many harmful bacteria’,", "d3ou5iuZlyA-00025-00011267-00011709": "and thinking that autism will imptove with only changing the bacterial composition, is a huge illusion.", "d3ou5iuZlyA-00026-00011709-00012616": "From what I have checked, no matter how much harmful bacteria is in the large intestine, it doesn't become a problem if it is not absorbed into the body.", "d3ou5iuZlyA-00027-00012616-00013113": "The problem is, that these bacteria grow too much and start to push themselves into the small intestines,", "d3ou5iuZlyA-00028-00013113-00013718": "which causes the small intestine to absorb many harmful toxic material created by these bacteria.", "d3ou5iuZlyA-00029-00013718-00014171": "In other words, it is not a matter of whether it is harmful or beneficial bacteria,", "d3ou5iuZlyA-00030-00014171-00014597": "but the fundamental problem is the overgrowth of bacteria and the SIBO symptoms caused by it.", "d3ou5iuZlyA-00031-00014597-00015369": "For example, ‘propionic acid’ is being confirmed as a very important cause of autism spectrum disorder.", "d3ou5iuZlyA-00032-00015369-00016315": "When propionic acid is injected to animals, many autistic behaviors including steriotyped behavior and anger behaviors are known to appear.", "d3ou5iuZlyA-00033-00016315-00016707": "In addition, when kids with autism spectrum order are tested of propionic acid concentration", "d3ou5iuZlyA-00034-00016707-00017012": "the results show high increases in the values compared to normal kids.", "d3ou5iuZlyA-00035-00017012-00018066": "In other words, kids with autism have more propionic acid absorbed into their blood, which causes brain damage.", "d3ou5iuZlyA-00036-00018066-00018520": "Propionic acid is a type of short-chain fatty acid created from intestinal bacteria.", "d3ou5iuZlyA-00037-00018520-00018930": "Then why would the blood concentration increase?", "d3ou5iuZlyA-00038-00018930-00019140": "It is because it is absorbed through the small intestines.", "d3ou5iuZlyA-00039-00019140-00019523": "If propionic acid remains inside the large intestine, and is ejected out regulary through feces,", "d3ou5iuZlyA-00040-00019523-00019979": "no matter how much the bacteria that generates propionic acid multiples in the large intestine,", "d3ou5iuZlyA-00041-00019979-00020206": "it will not be able to create autism symptoms.", "d3ou5iuZlyA-00042-00020206-00020621": "However, these bacteria are overflowing to the small intestine, ovrereplicates there,", "d3ou5iuZlyA-00043-00020621-00021107": "causes propionic acid to be absorbed through the small intestines, which increases blood concentration, which causes brain damage.", "d3ou5iuZlyA-00044-00021107-00021868": "In other words, the cause of high propionic acid concentration in the blood of autistic kids must be ‘STBO’ aswell.", "d3ou5iuZlyA-00045-00021868-00022546": "In the end, no matter how much harmful bacteria multuply, if we can stop SIBO,", "d3ou5iuZlyA-00046-00022546-00023009": "in other words overgrowth of bacteria in the small intestines, autism symptoms can be stabaily controlled.", "d3ou5iuZlyA-00047-00023009-00023150": "What is the next thing all of you need to understand?", "d3ou5iuZlyA-00048-00023150-00023580": "As autoimmune damage to the cerebral cortex progresses, autism fixes itself.", "d3ou5iuZlyA-00049-00023580-00024226": "There are two mechanisms that create damage to the cerebral cortex through autoimmune inflammatory responses.", "d3ou5iuZlyA-00050-00024226-00024872": "First, the underlying viral infections don’t stop at damaging only the brainstem or thalamus.", "d3ou5iuZlyA-00051-00024872-00025503": "Instead, it is estimated that it gradually progresses to total damage to the cerebral cortex.", "d3ou5iuZlyA-00052-00025503-00025920": "However, this progress seems to be very weak and slow.", "d3ou5iuZlyA-00053-00025920-00026211": "Because when kids with Aspurger’s syndrome are treated,", "d3ou5iuZlyA-00054-00026211-00026658": "most of them have stable intelligence even after aging.", "d3ou5iuZlyA-00055-00026658-00027204": "This is why I am deducing that ‘Aspurger’s syndrome is a state of being stopped at the viral infection stage’.", "d3ou5iuZlyA-00056-00027204-00027792": "And based on the fact that Aspurger’s syndrom does not result in severe intelligence damage, the progress seems to be very slow.", "d3ou5iuZlyA-00057-00027792-00028392": "But second, the neurotoxic substances intruced from SIBO causes increased autoimmune inflammatory responses.", "d3ou5iuZlyA-00058-00028392-00028818": "In other words, ‘cytokine’, an inflammatory substance is oversecreated,", "d3ou5iuZlyA-00059-00028818-00029045": "and this is what causes damage on the central nervous system.", "d3ou5iuZlyA-00060-00029045-00029314": "Brain damage caused by this autoimmune response", "d3ou5iuZlyA-00061-00029314-00029847": "the neurotoxic substance created from SIBO seems to progress at a very fast rate.", "d3ou5iuZlyA-00062-00029847-00030414": "Now, let’s breifly recap the process of autism development and exacerbation.", "d3ou5iuZlyA-00063-00030414-00030764": "In stage one, viral infections cause not only sensory process disorder", "d3ou5iuZlyA-00064-00030764-00031058": "but damage to the autonomic nervous system and digestive disorder aswell.", "d3ou5iuZlyA-00065-00031058-00031416": "With digestive disorder comes excess intestinal flora.", "d3ou5iuZlyA-00066-00031416-00031947": "The intestinal flora overreplicates, which then leaks into the small intestines and causes SIBO symptoms,", "d3ou5iuZlyA-00067-00031947-00032570": "and the SIBO symptoms cause many substances that cause autism to enter the body and attack the brain.", "d3ou5iuZlyA-00068-00032570-00033071": "Here, the process in which the brain is irreversably damaged is the <autism fixation stage>.", "d3ou5iuZlyA-00069-00033071-00033511": "Most kids with autism over 24 months old are considered to be in this stage,", "d3ou5iuZlyA-00070-00033511-00033947": "and therefore considered that the irreversable damage has already taken place.", "d3ou5iuZlyA-00071-00033947-00034271": "Why do we know this? Like I said a little ago,", "d3ou5iuZlyA-00072-00034271-00034744": "kids below 24 months old and kids with aspurger’s syndrome have no cognitive impairment,", "d3ou5iuZlyA-00073-00034744-00035326": "but kids over 24 months old with severe autism or aspurger’s syndrome,", "d3ou5iuZlyA-00074-00035326-00035753": "such as 36~48~56 month old kids have a certain amount of intlligence damage following them.", "d3ou5iuZlyA-00075-00035753-00036434": "Therefore, this <fixation stage> is a time where every moment is urgent,", "d3ou5iuZlyA-00076-00036434-00037121": "so I wouldhave to say that you should not delay treatment and treat your kids immediately, as soon as possible."}}, {"audio_id": "d3we_GiIkBo", "text": {"d3we_GiIkBo-00000-00000428-00000778": "Simon: We don't have that much support in this area. We need to gather some new members.", "d3we_GiIkBo-00001-00000778-00001054": "Mr. Dinosaur: I agree, we should ask someone cool.", "d3we_GiIkBo-00002-00001132-00001336": "Simon: Let me think about this later.", "d3we_GiIkBo-00003-00001530-00001900": "Blues: I will walk around, what a good temperature for the night.", "d3we_GiIkBo-00004-00003132-00003394": "Blues: I will get their attention.", "d3we_GiIkBo-00005-00003628-00003976": "Blues: I want to join Dogland against DTO. Can I join?", "d3we_GiIkBo-00006-00004050-00004208": "Mr. Dinosaur: Yes you can.", "d3we_GiIkBo-00007-00004458-00004730": "Simon: I need to find more members like you. See you later.", "d3we_GiIkBo-00008-00004984-00005300": "Simon: Why am I suddenly trapped here? Help!", "d3we_GiIkBo-00009-00005514-00005952": "PIg: We thought you fell for the money trap. We will take you hostage"}}, {"audio_id": "d3yGr2lGUnI", "text": {"d3yGr2lGUnI-00000-00000110-00000313": "- YOU HAVE TO BE ABLE TO TURN THE MESSAGE OFF.", "d3yGr2lGUnI-00001-00000320-00000663": "IF YOU CAN'T TURN THE MESSAGE OFF IN THIS EXAMPLE--", "d3yGr2lGUnI-00002-00000670-00001027": "THIS IS A GREAT EXAMPLE OF, DUDE, WE GOT OVERWHELMED.", "d3yGr2lGUnI-00003-00001034-00001398": "HOW DID WE REMOVE THOSE RECEPTORS?", "d3yGr2lGUnI-00004-00001404-00001681": "WELL, THE CELL ITSELF LITERALLY WILL GO, OKAY,", "d3yGr2lGUnI-00005-00001688-00002098": "THAT'S COOL, I'M GOING TO ENDOCYTOSE THE RECEPTORS.", "d3yGr2lGUnI-00006-00002105-00002622": "IT MAKES A LITTLE INTERNAL BUBBLE OF RECEPTOR.", "d3yGr2lGUnI-00007-00002629-00002909": "THE RECEPTOR IS INSIDE THAT BUBBLE I JUST MADE,", "d3yGr2lGUnI-00008-00002916-00003116": "AND THEN THE BUBBLE GOES INTO THE CELL,", "d3yGr2lGUnI-00009-00003123-00003386": "AND THE CELL SAYS, DUDE, YOU'RE GONE,", "d3yGr2lGUnI-00010-00003393-00003666": "YOUR GAME IS PLAYED, WE'VE HAD ENOUGH OF YOU.", "d3yGr2lGUnI-00011-00003673-00003887": "AND SO YOU CAN ACTUALLY--", "d3yGr2lGUnI-00012-00003893-00004127": "IF WE WANT TO STOP THE SIGNAL--", "d3yGr2lGUnI-00013-00004134-00004434": "I'M GOING TO MAKE YOU A LIST ON ANOTHER PIECE OF PAPER.", "d3yGr2lGUnI-00014-00004441-00004711": "LOOK, BECAUSE THIS IS A PIECE OF PAPER, ISN'T IT?", "d3yGr2lGUnI-00015-00004717-00004901": "I'M GOING TO MAKE IT RIGHT THERE--", "d3yGr2lGUnI-00016-00004908-00005475": "RIGHT THERE. STOP.", "d3yGr2lGUnI-00017-00005482-00005989": "NUMBER ONE, REMOVE RECEPTORS.", "d3yGr2lGUnI-00018-00005995-00006363": "THAT'S EASY, WE'RE JUST GOING TO ENDOCYTOSE OUR RECEPTOR,", "d3yGr2lGUnI-00019-00006369-00006606": "AND DIGEST IT, AND THAT'S WHAT WE'RE TALKING ABOUT,", "d3yGr2lGUnI-00020-00006613-00007110": "IF WE HAVE AN OVERDOSE OF STIMULUS WE MIGHT JUST REMOVE", "d3yGr2lGUnI-00021-00007117-00007584": "THE RECEPTORS TO STOP THAT BECAUSE IT GOT CRAZY.", "d3yGr2lGUnI-00022-00007590-00007831": "YOU CAN REMOVE THE SIGNAL,", "d3yGr2lGUnI-00023-00007837-00008214": "AND THE SIGNAL,", "d3yGr2lGUnI-00024-00008221-00008541": "HOW ARE YOU GOING TO REMOVE IT, STOP PRODUCING IT?", "d3yGr2lGUnI-00025-00008548-00008948": "OR ACTUALLY WE CAN DIGEST IT,", "d3yGr2lGUnI-00026-00008955-00009402": "AND USUALLY THIS INVOLVES AND ENZYME.", "d3yGr2lGUnI-00027-00009409-00009682": "LET ME SEE IF I GOT ALL OF THEM, DIGEST IT,", "d3yGr2lGUnI-00028-00009689-00010076": "REABSORB THE SIGNALING MOLECULE, ENDOCYTOSE IT.", "d3yGr2lGUnI-00029-00010083-00010283": "SO DIGESTING IT IS ONE WAY.", "d3yGr2lGUnI-00030-00010290-00010934": "YOU CAN ALSO REABSORB IT.", "d3yGr2lGUnI-00031-00010940-00011214": "BUT IN MY LITTLE EXAMPLE HERE THAT DOESN'T QUITE MAKE SENSE", "d3yGr2lGUnI-00032-00011221-00011398": "BECAUSE WHERE WOULD WE REABSORB IT TO.", "d3yGr2lGUnI-00033-00011404-00011688": "WHEN WE TALK ABOUT NEURONS AND NEURON SIGNALING THEN", "d3yGr2lGUnI-00034-00011694-00011905": "THAT WILL MAKE A LITTLE MORE SENSE.", "d3yGr2lGUnI-00035-00011911-00012482": "YOU HAVE SOME STRATEGIES, YOU CAN SEE THAT THERE ARE TOOLS", "d3yGr2lGUnI-00036-00012489-00012739": "THAT WE'RE GOING TO TAKE ADVANTAGE OF THAT HELP US,", "d3yGr2lGUnI-00037-00012746-00013193": "LIKE, REALLY COMMUNICATE PRECISELY FROM, DUDE,", "d3yGr2lGUnI-00038-00013199-00013583": "YOUR EYEBALL TO YOUR, LIKE, TAIL FEATHERS.", "d3yGr2lGUnI-00039-00013590-00013740": "OKAY, YOU DON'T HAVE TAIL FEATHERS,", "d3yGr2lGUnI-00040-00013746-00013923": "BUT YOU GET THE IDEA.", "d3yGr2lGUnI-00041-00013930-00014217": "NOW WE'RE GOING TO REVIEW OUR PATHWAYS.", "d3yGr2lGUnI-00042-00014224-00014564": "WE'RE GOING TO REVIEW LIKE FROM AN ANATOMICAL", "d3yGr2lGUnI-00043-00014571-00014888": "AND PHYSIOLOGICAL PERSPECTIVE.", "d3yGr2lGUnI-00044-00014894-00015175": "WE'RE GOING TO REVIEW A PATHWAY THINKING,", "d3yGr2lGUnI-00045-00015181-00015458": "REMEMBERING THAT ALL WE'RE DOING", "d3yGr2lGUnI-00046-00015465-00015849": "IS COMMUNICATING BETWEEN EACH PART OF THE PATHWAY.", "d3yGr2lGUnI-00047-00015855-00016106": "WE HAVE TO HAVE SOME FORM OF COMMUNICATION BETWEEN THEM,", "d3yGr2lGUnI-00048-00016112-00016623": "AND, DUDE, THAT'S WHAT PHYSIO IS ALL ABOUT.", "d3yGr2lGUnI-00049-00016629-00016836": "THAT'S WHAT IT'S ALL ABOUT, HEY."}}, {"audio_id": "d3WPq2flsH0", "text": {"d3WPq2flsH0-00000-00000000-00000200": "CBSE board result 2019", "d3WPq2flsH0-00001-00000200-00000297": "CBSE 12 th results", "d3WPq2flsH0-00002-00000297-00000347": "CBSE 10 th result", "d3WPq2flsH0-00003-00000347-00000397": "Result date"}}, {"audio_id": "d3XhrEOyKqA", "text": {"d3XhrEOyKqA-00000-00000000-00000480": "Hi, Everyone! So today we're gonna do some nail stamping over multichrome nail polish", "d3XhrEOyKqA-00001-00000480-00000977": "This polish I'm using is from Brazilian brand \"Hits\" and it's called \"Iris\".", "d3XhrEOyKqA-00002-00001080-00001518": "Before I get started I'm just gonna go over with acetone over my nails", "d3XhrEOyKqA-00003-00001518-00002039": "Some people use like a dehydrator This is basically just to get rid of any oils", "d3XhrEOyKqA-00004-00002039-00002394": "or anything in your nail so that the polish adheres better", "d3XhrEOyKqA-00005-00002394-00002742": "To go over with the acetone I'm using a precision brush", "d3XhrEOyKqA-00006-00002742-00003048": "This is just like a makeup brush for the eyes", "d3XhrEOyKqA-00007-00003048-00003588": "We're gonna dip it in acetone and just put it over our nails one by one", "d3XhrEOyKqA-00008-00003588-00003804": "Making sure you cover all the nails", "d3XhrEOyKqA-00009-00003804-00004116": "A little bit of the skin on the side the cuticles", "d3XhrEOyKqA-00010-00004116-00004596": "Just to get rid of any oils that could get in the way of your manicure looking great", "d3XhrEOyKqA-00011-00004674-00005094": "I will speed up some of these sections here because I am really slow", "d3XhrEOyKqA-00012-00005094-00005652": "But I'll make sure to leave at least the first nail or the last nail at normal speed", "d3XhrEOyKqA-00013-00005652-00006042": "Just so you guys have some idea of how long that process takes", "d3XhrEOyKqA-00014-00006096-00006900": "After that I'm gonna go over with the base coat I'm using Ünt “Ready for Takeoff”", "d3XhrEOyKqA-00015-00006900-00007416": "Which is a peel off base coat just because I'm using a lot of nail polish and", "d3XhrEOyKqA-00016-00007416-00007854": "afterwards just make it easier to remove so I don't have to use acetone as much", "d3XhrEOyKqA-00017-00007938-00008466": "so again going over each nail with a very thin coat of the base coat", "d3XhrEOyKqA-00018-00009078-00009414": "on the thumb here you can see how slow I am That's at normal speed", "d3XhrEOyKqA-00019-00009414-00009630": "And I just turned the brush because I did have like", "d3XhrEOyKqA-00020-00009630-00009870": "blobs of base coat on both sides", "d3XhrEOyKqA-00021-00009870-00010188": "Not a great application but it works, you know", "d3XhrEOyKqA-00022-00010608-00011160": "And after we put on the base coat While we waited for it to dry", "d3XhrEOyKqA-00023-00011212-00011754": "Ünt recommends I think about six to seven minutes We're gonna open our stamping nail plate", "d3XhrEOyKqA-00024-00011754-00012120": "This is from Nicole diary And it has some dragonfly designs", "d3XhrEOyKqA-00025-00012120-00012366": "Which I think are going to match pretty well with the multi Chrome", "d3XhrEOyKqA-00026-00012528-00013319": "and the first thing we're going to do is remove that like blue protection cover that it has", "d3XhrEOyKqA-00027-00013319-00013734": "I use tweezers for that because I think it helps just be careful because like my tweezers are metal", "d3XhrEOyKqA-00028-00013932-00014304": "I want to make sure I'm not scraping any of the plate with those tweezers", "d3XhrEOyKqA-00029-00014304-00014568": "so I just use it to help me get started", "d3XhrEOyKqA-00030-00014568-00015084": "and after that peel it off by myself one thing to be careful with these plate also", "d3XhrEOyKqA-00031-00015084-00015558": "this is metal and it's really thin metal so when you hold it like I'm holding", "d3XhrEOyKqA-00032-00015558-00016044": "right there be careful because if that slips it can hurt your fingers", "d3XhrEOyKqA-00033-00016044-00016416": "and can cut your fingers and yes it has happened to me twice", "d3XhrEOyKqA-00034-00016416-00016524": "so yeah just be careful", "d3XhrEOyKqA-00035-00016524-00016812": "some plates have a protection cover like the Born Pretty ones", "d3XhrEOyKqA-00036-00016812-00017070": "but these Nicole Diary ones don't have it", "d3XhrEOyKqA-00037-00017364-00017880": "and now that our base coat is dry I'm gonna go over it with the multichrome polish", "d3XhrEOyKqA-00038-00017880-00018312": "some people like to do the multi-chrome over black", "d3XhrEOyKqA-00039-00018312-00018894": "I personally like how it looks by itself for this one I use about three coats", "d3XhrEOyKqA-00040-00018894-00019254": "and this again it is “Iris” by Brazilian brand “Hits”", "d3XhrEOyKqA-00041-00019254-00019422": "I really like this one", "d3XhrEOyKqA-00042-00019422-00019860": "is a very green and then it has some shades of pink", "d3XhrEOyKqA-00043-00019860-00020022": "some shades of gold", "d3XhrEOyKqA-00044-00020094-00020286": "it just gives a really nice effect", "d3XhrEOyKqA-00045-00020286-00020688": "and you will see I'm skipping my ring finger", "d3XhrEOyKqA-00046-00020688-00021042": "because my plan was to use a different multi-chrome for that one", "d3XhrEOyKqA-00047-00021042-00021420": "but I messed it up (spoiler alert) as you guys will see", "d3XhrEOyKqA-00048-00021420-00021612": "but that's the reason why I'm skipping", "d3XhrEOyKqA-00049-00021612-00021948": "my intention was to do like an accent nail on that one", "d3XhrEOyKqA-00050-00021948-00022080": "didn't quite work", "d3XhrEOyKqA-00051-00022182-00022722": "now going in with the second coat over the nails you guys can see it starts to build up", "d3XhrEOyKqA-00052-00022722-00022974": "if you are wearing black underneath it", "d3XhrEOyKqA-00053-00022974-00023220": "you probably can do just one coat of the multi Chrome", "d3XhrEOyKqA-00054-00023220-00023766": "and one coat of the black under it so if you don't like as many layers on your nail", "d3XhrEOyKqA-00055-00023766-00023976": "that could be an approach for you", "d3XhrEOyKqA-00056-00023976-00024278": "but again I personally like the way it looks with just the multichrome", "d3XhrEOyKqA-00057-00024278-00025164": "make sure you're wrapping the tip when you're putting on a nail polish", "d3XhrEOyKqA-00058-00025164-00025302": "that's what I do like that last step", "d3XhrEOyKqA-00059-00025302-00025572": "you can see me putting the brush on the tip of the nail", "d3XhrEOyKqA-00060-00025572-00025800": "that helps it stay longer and", "d3XhrEOyKqA-00061-00025800-00026172": "when I mess up a little bit I go in with my steel stick", "d3XhrEOyKqA-00062-00026172-00026466": "just to clean it up while the polish is still wet", "d3XhrEOyKqA-00063-00026466-00026838": "because if you wait for it to dry it's just going to be harder to do the cleanup", "d3XhrEOyKqA-00064-00027588-00027995": "this is what it looks like with three coats you can see that multi Chrome very well", "d3XhrEOyKqA-00065-00027995-00028212": "like I see a lot of the gold a lot of the pink", "d3XhrEOyKqA-00066-00028332-00028614": "and now for my ring finger this is where I messed up", "d3XhrEOyKqA-00067-00028614-00028800": "the plan was to do a different multi-chrome", "d3XhrEOyKqA-00068-00028800-00028956": "but I put on the same one", "d3XhrEOyKqA-00069-00028956-00029244": "for some reason I didn't notice it was the same one", "d3XhrEOyKqA-00070-00029430-00029783": "meanwhile while I'm waiting to go over the second coat on that one", "d3XhrEOyKqA-00071-00029783-00030024": "I'm doing the top coat on the other fingers", "d3XhrEOyKqA-00072-00030024-00030408": "I'm using “Diamond Gel” by Brazilian brand “Risqué”", "d3XhrEOyKqA-00073-00030408-00030732": "it is not a gel polish it just says like it's gel effect", "d3XhrEOyKqA-00074-00030732-00031133": "so you don't need to cure it or anything it's just a regular top coat", "d3XhrEOyKqA-00075-00031680-00032220": "Now the second layerof the same polish on the ring finger and on the third coat I noticed", "d3XhrEOyKqA-00076-00032220-00032639": "and try to fix my mistakes there and I grab the right color which is that one", "d3XhrEOyKqA-00077-00032639-00033114": "also by Brazilian brand “Hits” and it's called “Ocípite”", "d3XhrEOyKqA-00078-00033198-00033504": "and that one has some more flakes", "d3XhrEOyKqA-00079-00033504-00033858": "of like a pink and purple it also has a", "d3XhrEOyKqA-00080-00033858-00034182": "little bit of the green a little bit of the gold in there", "d3XhrEOyKqA-00081-00034182-00034476": "but I do see a lot of the pinks and purples", "d3XhrEOyKqA-00082-00034476-00034776": "it won't come off as much because we are", "d3XhrEOyKqA-00083-00034776-00035016": "doing it over the other multi-chrome", "d3XhrEOyKqA-00084-00035016-00035418": "if I had done three layers of that one it would come off a", "d3XhrEOyKqA-00085-00035418-00035502": "lot more pinky", "d3XhrEOyKqA-00086-00035502-00035706": "and there you can see a little bit of the difference", "d3XhrEOyKqA-00087-00035706-00036180": "again it is very subtle because I did do two layers of the wrong polish", "d3XhrEOyKqA-00088-00036180-00036576": "going in with the top coat I'm just using that quick dry", "d3XhrEOyKqA-00089-00036576-00037068": "top coat to protect the nail and make it dry faster for us to put the stamping over it", "d3XhrEOyKqA-00090-00037134-00037470": "now this is time to stamp! I did wait for it to dry a", "d3XhrEOyKqA-00091-00037470-00037620": "little bit before getting into that", "d3XhrEOyKqA-00092-00037620-00037842": "and yeah this is a beautiful plate!", "d3XhrEOyKqA-00093-00037842-00038082": "I think it's going to work great with the multi-chrome", "d3XhrEOyKqA-00094-00038082-00038460": "it looks like the wings of the dragonflies and for my", "d3XhrEOyKqA-00095-00038460-00038700": "stamping I have a silicone mat", "d3XhrEOyKqA-00096-00038700-00038910": "which is actually from like cooking for you to", "d3XhrEOyKqA-00097-00038910-00039498": "use with pots and pans but it works just fine it's really good for cleaning your scraper", "d3XhrEOyKqA-00098-00039498-00039984": "and then you can just peel off the polish from the silicone and just to", "d3XhrEOyKqA-00099-00039984-00040206": "you know be a support for your plate", "d3XhrEOyKqA-00100-00040206-00040428": "now I'm checking to make sure everything is", "d3XhrEOyKqA-00101-00040428-00040740": "dry that is not gonna mess up my polish underneath it", "d3XhrEOyKqA-00102-00040740-00040998": "I am using stamping specific", "d3XhrEOyKqA-00103-00040998-00041286": "polish from Brazilian brand “Carimbos de Unha” (Nail Stamps)", "d3XhrEOyKqA-00104-00041286-00041688": "you don't need to use a specific stamping nail polish but", "d3XhrEOyKqA-00105-00041688-00042096": "it's good because those are opaque, very opaque", "d3XhrEOyKqA-00106-00042096-00042480": "if you do have regular nail polish that you know is opaque enough", "d3XhrEOyKqA-00107-00042480-00042606": "it could work as well", "d3XhrEOyKqA-00108-00042606-00043194": "but stamping nail polishes are basically the same price so I like to use it", "d3XhrEOyKqA-00109-00043194-00043614": "I do have like a “Sinful Colors”  which is called “Black on Black”", "d3XhrEOyKqA-00110-00043614-00044100": "which I think might work, it is a one coat black so maybe it will work for stamping", "d3XhrEOyKqA-00111-00044100-00044418": "you can always test it out to see if yours is going to work or not", "d3XhrEOyKqA-00112-00044418-00044754": "and I try to just bounce the stamper over the plate", "d3XhrEOyKqA-00113-00044754-00044922": "to pick up the design nicely", "d3XhrEOyKqA-00114-00045072-00045684": "and for my pinky nail I'm picking up that design that mimics the wings of the dragonfly", "d3XhrEOyKqA-00115-00045684-00046104": "and just seeing it where I'm placing it I did mess up a little bit", "d3XhrEOyKqA-00116-00046104-00046404": "you will see that the tip of my nail", "d3XhrEOyKqA-00117-00046404-00046824": "brushes up against the stamper and picks up the design right there", "d3XhrEOyKqA-00118-00046824-00047538": "and it generates like a little gap on it there right before I stamp so be careful", "d3XhrEOyKqA-00119-00047538-00047790": "that's why I have a gap at the top I", "d3XhrEOyKqA-00120-00047790-00048144": "also did have a gap at the bottom that I didn't really like with that stamping", "d3XhrEOyKqA-00121-00048144-00048690": "but it's fine I was trying to check how I could make as little of a mess as possible", "d3XhrEOyKqA-00122-00048690-00049002": "but we can always clean it up later I'll show you guys how", "d3XhrEOyKqA-00123-00049128-00049680": "now for my ring finger I wanted to pick up one of the more single designs", "d3XhrEOyKqA-00124-00049680-00049992": "not the ones that are all over the nail the more detailed ones", "d3XhrEOyKqA-00125-00049992-00050406": "and I really like this dragonfly that has kind of like a halo effect", "d3XhrEOyKqA-00126-00050406-00051108": "I thought it was going to look good on the more pink/magenta color that we used on the ring finger", "d3XhrEOyKqA-00127-00051216-00051696": "and I'm using a “Born Pretty” stamper it's like a clear silicone stamper", "d3XhrEOyKqA-00128-00051696-00051846": "but you can use any you like", "d3XhrEOyKqA-00129-00051846-00052194": "I like the clear ones because you can see where you are stamping", "d3XhrEOyKqA-00130-00052248-00052698": "and in between designs I just clean that on adhesive surface", "d3XhrEOyKqA-00131-00052698-00052902": "I use a lint roller for that", "d3XhrEOyKqA-00132-00052902-00053370": "never use like acetone or polish removal on your stamper", "d3XhrEOyKqA-00133-00053484-00053760": "now moving over for the thumb design and", "d3XhrEOyKqA-00134-00053760-00054012": "as you guys can see I'm not cleaning my plate in between", "d3XhrEOyKqA-00135-00054012-00054641": "I'm just making sure I'm not scraping over any design I want to", "d3XhrEOyKqA-00136-00054641-00054972": "use later and then I can just clean it once I'm done", "d3XhrEOyKqA-00137-00054972-00055067": "I find that easier", "d3XhrEOyKqA-00138-00055067-00055517": "it's not always possible depending on the designs you want to use but makes it easier", "d3XhrEOyKqA-00139-00055517-00055920": "and I really like this design it's like a big dragonfly in", "d3XhrEOyKqA-00140-00055920-00056178": "the forefront and a smaller one in the back", "d3XhrEOyKqA-00141-00056232-00056700": "and here's why I really like the clear stamper because then you can do what I'm doing right now", "d3XhrEOyKqA-00142-00056700-00057108": "which is checking which orientation is going to look better and", "d3XhrEOyKqA-00143-00057108-00057414": "what part of the design I want to stamp on the nail", "d3XhrEOyKqA-00144-00057504-00057917": "I personally like to do the design facing me that way", "d3XhrEOyKqA-00145-00057917-00058386": "So, you know, with the top part at the outside of my nail and", "d3XhrEOyKqA-00146-00058386-00058548": "the bottom part near the cuticle", "d3XhrEOyKqA-00147-00058548-00059010": "some people like to do the other way around like the upside down version of that", "d3XhrEOyKqA-00148-00059010-00059538": "but really you can do what you think looks prettier and you can do like sideways, upside down", "d3XhrEOyKqA-00149-00059538-00059934": "I personally like it having it facing me in that orientation", "d3XhrEOyKqA-00150-00060054-00060329": "now for my index finger I try to pick up", "d3XhrEOyKqA-00151-00060329-00061026": "this entire nail design which is a bunch of little dragonflies", "d3XhrEOyKqA-00152-00061026-00061241": "I didn't like the way it looked", "d3XhrEOyKqA-00153-00061241-00061644": "you can't really see on camera but it looks really splotchy", "d3XhrEOyKqA-00154-00061644-00062274": "I can't really tell how else to say it but it looks like it has a lot of nail polish on it", "d3XhrEOyKqA-00155-00062274-00062496": "and I tried to stamp it but I was", "d3XhrEOyKqA-00156-00062496-00062904": "like “I don't think that's going to look good” so I just cleaned my stamper", "d3XhrEOyKqA-00157-00062904-00063384": "and cleaned my plate and I tried it again I had to clean the plate here because", "d3XhrEOyKqA-00158-00063384-00063641": "I wanted to pick up the same design that I", "d3XhrEOyKqA-00159-00063641-00064044": "had tried to pick up earlier so it was like dirty with nail polish", "d3XhrEOyKqA-00160-00064044-00064379": "I'm just using a cotton ball and some acetone", "d3XhrEOyKqA-00161-00064379-00064962": "I might switch over to something that doesn't have as much lint I guess as a cotton ball", "d3XhrEOyKqA-00162-00064962-00065255": "because on these very small designs", "d3XhrEOyKqA-00163-00065255-00065736": "it leaves off some little pieces of cotton that it picks up", "d3XhrEOyKqA-00164-00065736-00065916": "because the designs are so detailed", "d3XhrEOyKqA-00165-00066030-00066648": "so I'll try to use a lint-free alternative for our next times to avoid that", "d3XhrEOyKqA-00166-00066648-00066882": "and I'm just you know taking the opportunity", "d3XhrEOyKqA-00167-00066882-00067254": "to clean the rest of it as well since I'm there and use the acetone", "d3XhrEOyKqA-00168-00067350-00067530": "and there we go to try again you just", "d3XhrEOyKqA-00169-00067530-00067818": "have to wait for the acetone to dry to pick it up again", "d3XhrEOyKqA-00170-00067818-00068280": "all the stamping portions I'm doing in real time so you", "d3XhrEOyKqA-00171-00068280-00068454": "guys can see it how long it takes", "d3XhrEOyKqA-00172-00068454-00068748": "even me dropping the scraper over the design", "d3XhrEOyKqA-00173-00068748-00069198": "but that's fine we can still use it the polish is still there", "d3XhrEOyKqA-00174-00069198-00069648": "we can still pick up the design no worries just me being clumsy", "d3XhrEOyKqA-00175-00069648-00069882": "again we're just gonna do a quick bounce", "d3XhrEOyKqA-00176-00069882-00070188": "with the stamper over the plate to pick up the design", "d3XhrEOyKqA-00177-00070188-00070722": "no pressing no going back and forth and I know you probably can't tell the difference", "d3XhrEOyKqA-00178-00070722-00070974": "but it looks much better than the first time around", "d3XhrEOyKqA-00179-00071052-00071442": "and now again just checking like which pieces are going to look better on the nail", "d3XhrEOyKqA-00180-00071442-00071694": "and then we are gonna stamp it", "d3XhrEOyKqA-00181-00072324-00072594": "and this one did make a lot of a mess on my finger", "d3XhrEOyKqA-00182-00072594-00072936": "but as I mentioned before I will show you guys in a minute how to clean that up", "d3XhrEOyKqA-00183-00072936-00073374": "it's no worries really and that cleanup you can do afterwards", "d3XhrEOyKqA-00184-00073374-00073602": "even if it's dry it's no problem", "d3XhrEOyKqA-00185-00073602-00074112": "it's not like cleaning up the nail polish that you have to do while it's still wet", "d3XhrEOyKqA-00186-00074790-00075396": "for my middle finger I'm using that one which is also the wing of a dragonfly", "d3XhrEOyKqA-00187-00075396-00075720": "and I wanted to make sure I got a little bit of the outline", "d3XhrEOyKqA-00188-00075720-00075966": "instead of like stamping it all over the nail", "d3XhrEOyKqA-00189-00075966-00076584": "so you guys can see at the bottom I did leave a little bit of that curve of the winged design", "d3XhrEOyKqA-00190-00078228-00078540": "and there you go this is how all the", "d3XhrEOyKqA-00191-00078540-00078900": "designs look on the nail before the cleanup which we'll get to in a minute", "d3XhrEOyKqA-00192-00078960-00079080": "and I really like it!", "d3XhrEOyKqA-00193-00079140-00079476": "so for the cleanup you're just gonna need some tape", "d3XhrEOyKqA-00194-00079476-00079728": "or really anything that's adhesive", "d3XhrEOyKqA-00195-00079794-00080322": "and you're just gonna pick those designs up like just stick them from your fingers", "d3XhrEOyKqA-00196-00080322-00081018": "I am being very careful here to not touch the nail especially because I have peel off base coat", "d3XhrEOyKqA-00197-00081072-00081510": "and it is sped up quite a lot it is a little bit tedious", "d3XhrEOyKqA-00198-00081510-00081942": "an alternative could be using liquid latex on your nails", "d3XhrEOyKqA-00199-00081942-00082152": "but I avoid doing that", "d3XhrEOyKqA-00200-00082152-00082440": "again because of the peel off base coat doesn't work as well", "d3XhrEOyKqA-00201-00082626-00082872": "you won't be able to clean off probably all of it,", "d3XhrEOyKqA-00202-00082872-00083454": "like I wasn't, but then we can go in and just clean the finer details with the precision brush", "d3XhrEOyKqA-00203-00083454-00083766": "and a little bit of acetone as you guys will see in a minute", "d3XhrEOyKqA-00204-00083766-00084078": "but I tried to clean off as much as I could with the tape", "d3XhrEOyKqA-00205-00084078-00084486": "because the stamping nail polish is really opaque so", "d3XhrEOyKqA-00206-00084486-00084828": "when you try to do that cleanup it can stain a lot", "d3XhrEOyKqA-00207-00084828-00085158": "and take a lot of time to clean up with the acetone so just be", "d3XhrEOyKqA-00208-00085158-00085692": "mindful of that still doable just be mindful that it is very intense and opaque", "d3XhrEOyKqA-00209-00085938-00086508": "and this is how it looks all cleaned up", "d3XhrEOyKqA-00210-00086508-00086928": "I personally loved it it turned out I think even better than I expected!", "d3XhrEOyKqA-00211-00086928-00087354": "Minus the ring finger which I wanted to be a little more of an accent", "d3XhrEOyKqA-00212-00087354-00087738": "and I'm just gonna put a top coat over it to seal the design", "d3XhrEOyKqA-00213-00087738-00088044": "I really love “Seche Vite” quick dry", "d3XhrEOyKqA-00214-00088044-00088386": "it dries like in a second and it looks gorgeous", "d3XhrEOyKqA-00215-00088386-00088866": "one thing to be mindful of is you gotta wait for the stamping to dry a little bit", "d3XhrEOyKqA-00216-00088866-00089328": "before you go over with a top coat just to make sure you're not", "d3XhrEOyKqA-00217-00089328-00089958": "dragging the design or you know damaging it or making it look bad", "d3XhrEOyKqA-00218-00089958-00090432": "and one thing I also do is I try to put a lot of top coat", "d3XhrEOyKqA-00219-00090432-00090648": "I'll show you guys in the thumb a little bit better", "d3XhrEOyKqA-00220-00090648-00090876": "but also wait for it to dry a little bit", "d3XhrEOyKqA-00221-00090876-00091290": "you don't want to ruin the beautiful design you just worked really hard on", "d3XhrEOyKqA-00222-00092142-00092658": "so here on the thumb I'm gonna show you guys you just try to pick up a lot of top coat", "d3XhrEOyKqA-00223-00092658-00093018": "and then instead of sliding the brush through your nail", "d3XhrEOyKqA-00224-00093018-00093354": "you are kind of just sliding the top coat liquid", "d3XhrEOyKqA-00225-00093414-00093594": "I hope you guys can see it", "d3XhrEOyKqA-00226-00093594-00093912": "so you avoid touching the brush directly to the nail", "d3XhrEOyKqA-00227-00093912-00094590": "that really helps to not drag the design it does mean using a lot of top coat", "d3XhrEOyKqA-00228-00094590-00095142": "so you guys will see I clean up a little bit with the steel stick there at the end", "d3XhrEOyKqA-00229-00095142-00095592": "because it it pools up a little bit in the sides of my finger", "d3XhrEOyKqA-00230-00095592-00095880": "apologies about the focus by the way I'll try to fix", "d3XhrEOyKqA-00231-00095880-00096012": "that on next ones", "d3XhrEOyKqA-00232-00096090-00096588": "but yeah use a lot of top code and make sure you're dragging the top coat and", "d3XhrEOyKqA-00233-00096588-00096834": "not actually dragging the brush through", "d3XhrEOyKqA-00234-00096834-00097272": "your nail that will help you with any dragging or staining of your designs", "d3XhrEOyKqA-00235-00098040-00098292": "and this is what the design looks like indoors", "d3XhrEOyKqA-00236-00098292-00098772": "this is night time I'm just using a ring light very like tiny little ring light", "d3XhrEOyKqA-00237-00098772-00098958": "you can see the multi-chrome very well", "d3XhrEOyKqA-00238-00099018-00099492": "and I'll show you guys in a minute what it looks like in daytime the next day", "d3XhrEOyKqA-00239-00100194-00100494": "so yeah this is what it looks like on daylight the next day", "d3XhrEOyKqA-00240-00100494-00100782": "I hope you guys liked it I'm really proud of this one", "d3XhrEOyKqA-00241-00100782-00100902": "I think it came out great", "d3XhrEOyKqA-00242-00100902-00101221": "and I'll see you on the next one bye bye =]"}}, {"audio_id": "d3co7m8FCNu", "text": {"d3co7m8FCNu-00000-00001850-00002150": "yeah"}}]