Question: Where are liver stem cells (oval cells) located?

Answer: in the canals of hering


Question: What are stained here with an immunohistochemical stain for cytokeratin 7?

Answer: bile duct cells and canals of hering


Question: What are bile duct cells and canals of Hering stained here with for cytokeratin 7?

Answer: an immunohistochemical stain


Question: Are bile duct cells and canals of Hering stained here with an immunohistochemical stain for cytokeratin 7?

Answer: yes


Question: What shows dissolution of the tissue?

Answer: an infarct in the brain


Question: What does an infarct in the brain show of the tissue?

Answer: dissolution of the tissue


Question: Does an infarct in the brain show dissolution of the tissue?

Answer: yes


Question: Does preserved show dissolution of the tissue?

Answer: no


Question: What represent foci of fat necrosis with calcium soap formation at sites of lipid breakdown in the mesentery?

Answer: the areas of white chalky deposits


Question: Where do areas of white chalky deposits represent foci of fat necrosis with calcium soap formation?

Answer: at sites of lipid breakdown in the mesentery


Question: What do the areas of white chalky deposits represent?

Answer: foci of fat necrosis


Question: How do the areas of white chalky deposits represent foci of fat necrosis?

Answer: with calcium soap formation (saponification)


Question: Do the areas of white chalky deposits represent foci of fat necrosis with calcium soap formation at sites of lipid breakdown in the mesentery?

Answer: yes


Question: Do the histone subunits represent foci of fat necrosis with calcium soap formation at sites of lipid breakdown in the mesentery?

Answer: no


Question: What is ischemia?

Answer: the cause of reversible injury


Question: What is the cause of reversible injury?

Answer: ischemia


Question: What is hypertrophy?

Answer: the cellular adaptation depicted here


Question: Is the cellular adaptation depicted here hypertrophy?

Answer: yes


Question: Is there an infarct in the brain hypertrophy?

Answer: no


Question: What is ischemic coagulative necrosis?

Answer: the irreversible injury


Question: What is the irreversible injury?

Answer: ischemic coagulative necrosis


Question: Is the irreversible injury ischemic coagulative necrosis?

Answer: yes


Question: What is thicker than 2 cm (normal,  1-1.5 cm) in the example of myocardial hypertrophy lower left?

Answer: the left ventricular wall


Question: How many cm (normal,  1-1.5 cm) is the left ventricular wall thicker than in the example of myocardial hypertrophy lower left?

Answer: 2 cm


Question: Is the left ventricular wall thicker than 2 cm (normal,  1-1.5 cm) in the example of myocardial hypertrophy lower left?

Answer: yes


Question: Is reversible injury thicker than 2 cm normal,  1-1.5 cm in the example of myocardial hypertrophy lower left?

Answer: no


Question: What shows functional effects without any gross or light microscopic changes,  or reversible changes such as cellular swelling and fatty change?

Answer: reversibly injured myocardium


Question: Does reversibly injured myocardium show functional effects without any gross or light microscopic changes,  or reversible changes such as cellular swelling and fatty change?

Answer: yes


Question: Does an infarct in the brain show functional effects without any gross or light microscopic changes,  or reversible changes such as cellular swelling and fatty change (shown here)?

Answer: no


Question: What represents an acute myocardial infarction in the specimen showing necrosis?

Answer: the transmural light area in the posterolateral left ventricle


Question: What does the transmural light area in the posterolateral left ventricle represent in the specimen showing necrosis?

Answer: acute myocardial infarction


Question: Does the transmural light area in the posterolateral left ventricle represent an acute myocardial infarction in the specimen showing necrosis?

Answer: yes


Question: Does reversible injury represent an acute myocardial infarction in the specimen showing necrosis?

Answer: no


Question: How many transverse sections of myocardium were stained with triphenyltetra-zolium chloride,  an enzyme substrate that colors viable myocardium magenta?

Answer: three


Question: What were stained with triphenyltetra-zolium chloride,  an enzyme substrate that colors viable myocardium magenta?

Answer: all three transverse sections of myocardium


Question: What were all three transverse sections of myocardium stained with?

Answer: triphenyltetra-zolium chloride


Question: Were all three transverse sections of myocardium stained with triphenyltetra-zolium chloride,  an enzyme substrate that colors viable myocardium magenta?

Answer: yes


Question: What is due to enzyme loss after cell death?

Answer: failure to stain


Question: Is failure to stain due to enzyme loss after cell death?

Answer: yes


Question: When is failure to stain due to enzyme loss?

Answer: after cell death


Question: Is atrophy seen in the brain?

Answer: yes


Question: What is caused by aging and reduced blood supply?

Answer: atrophy of the brain


Question: What of the brain is caused by aging?

Answer: atrophy


Question: Is atrophy of the brain caused by aging and reduced blood supply?

Answer: yes


Question: Is reversible injury caused by aging and reduced blood supply?

Answer: no


Question: What have been stripped from the bottom half of each specimen to show the surface of the brain?

Answer: the meninges


Question: What have the meninges been stripped from?

Answer: the bottom half of each specimen


Question: Have the meninges been stripped from the bottom half of each specimen to show the surface of the brain?

Answer: yes


Question: Have the necrotic cells been stripped from the bottom half of each specimen to show the surface of the brain?

Answer: no


Question: What is called the Prussian blue reaction?

Answer: a special staining process


Question: What is shown by a special staining process called the Prussian blue reaction?

Answer: iron deposits


Question: Are iron deposits shown by a special staining process call the Prussian blue reaction?

Answer: yes


Question: What show an inflammatory reaction in the myocardium after ischemic necrosis infarction?

Answer: the photomicrographs


Question: What do the photomicrographs show in the myocardium after ischemic necrosis infarction?

Answer: an inflammatory reaction


Question: Do the photomicrographs show an inflammatory reaction in the myocardium after ischemic necrosis infarction?

Answer: yes


Question: Do apoptotic cells in colonic epithelium show an inflammatory reaction in the myocardium after ischemic necrosis infarction?

Answer: no


Question: When do the photomicrographs show an inflammatory reaction in the myocardium ?

Answer: after ischemic necrosis infarction


Question: What show an inflammatory reaction in the myocardium after ischemic necrosis infarction?

Answer: the photomicrographs


Question: Where do the photomicrographs show an inflammatory reaction after ischemic necrosis infarction?

Answer: in the myocardium


Question: When do the photomicrographs show an inflammatory reaction in the myocardium after ischemic necrosis infarction?

Answer: after ischemic necrosis infarction


Question: What do the photomicrographs show in the myocardium after ischemic necrosis infarction?

Answer: an inflammatory reaction


Question: Do the photomicrographs show an inflammatory reaction in the myocardium after ischemic necrosis infarction?

Answer: yes


Question: Do the meninges show an inflammatory reaction in the myocardium after ischemic necrosis infarction?

Answer: no


Question: When do the photomicrographs show an inflammatory reaction in the myocardium ?

Answer: after ischemic necrosis infarction


Question: Two have lost whose nuclei ?

Answer: their


Question: What stained red and cytoplasm green?

Answer: healthy neutrophils with nuclei


Question: Are healthy neutrophils with nuclei stain red and cytoplasm green?

Answer: yes


Question: Did the areas of white chalky deposits stain red and cytoplasm green?

Answer: no


Question: Two have lost whose nuclei ?

Answer: their


Question: What is separated from the dermis by a focal collection of serous effusion?

Answer: the epidermis


Question: What does the low-power view of a cross section of a skin blister show?

Answer: the epidermis separated from the dermis by a focal collection serous effusion


Question: How does low-power view of a cross section of a skin blister show the epidermis separated from the dermis?

Answer: by a focal collection serous effusion


Question: Is low-power view of a cross section of a skin blister showing the epidermis separated from the dermis by a focal collection of serous effusion?

Answer: yes


Question: Is the irreversible injury separated from the dermis by a focal collection of serous effusion?

Answer: no


Question: When are the majority of tissue macrophages derived from hematopoietic precursors?

Answer: during inflammatory reactions


Question: When are the majority of tissue macrophages derived from hematopoietic precursors?

Answer: during inflammatory reactions


Question: When are the majority of tissue macrophages derived from hematopoietic precursors?

Answer: during inflammatory reactions


Question: What is stained blue by the trichrome stain?

Answer: collagen


Question: Is Collagen stained blue by the trichrome stain?

Answer: yes


Question: Is the injurious stimulus stained blue by the trichrome stain?

Answer: no


Question: What is the major initiator of coagulation?

Answer: tissue factor


Question: What is tissue factor, in vivo?

Answer: the major initiator of coagulation


Question: Is tissue factor the major initiator of coagulation,  which is amplified by feedback loops involving thrombin in vivo?

Answer: yes


Question: Is the major initiator of coagulation amplified by feedback loops involving thrombin?

Answer: yes


Question: What are inactive factors?

Answer: the red polypeptides


Question: Are the red polypeptides inactive factors?

Answer: yes


Question: Are all three transverse sections of myocardium inactive factors?

Answer: no


Question: What color are the active factors?

Answer: dark green


Question: Are the dark green polypeptides active factors?

Answer: yes


Question: What correspond to cofactors?

Answer: the light green polypeptides


Question: What do the light green polypeptides correspond to?

Answer: cofactors


Question: Do the light green polypeptides correspond to cofactors?

Answer: yes


Question: Do the necrotic cells correspond to cofactors?

Answer: no


Question: What consists of a protease, a substrate, and a reaction accelerator assembled on a platelet phospholipid surface?

Answer: the initial reaction complex


Question: What does the initial reaction complex consist of?

Answer: a protease (factor viia)


Question: Does the initial reaction complex consist of a protease, a substrate, and a reaction accelerator assembled on a platelet phospholipid surface?

Answer: yes


Question: Does atrophy of the brain consist of a protease assembled on a platelet phospholipid surface?

Answer: no


Question: What is stained for elastic tissue?

Answer: a thrombosed artery


Question: Is a thrombosed artery stained for elastic tissue?

Answer: yes


Question: What is lodged in a pulmonary artery branch?

Answer: embolus


Question: Is embolus derived from a lower-extremity deep venous thrombus lodged in a pulmonary artery branch?

Answer: yes


Question: Is edema lodged in a pulmonary artery branch?

Answer: no


Question: What is replaced by a large fibrotic scar?

Answer: remote kidney infarct


Question: What is the remote kidney infarct replaced by?

Answer: a large fibrotic scar


Question: How is the remote kidney infarct replaced?

Answer: by a large fibrotic scar


Question: Is the remote kidney infarct replaced by a large fibrotic scar?

Answer: yes


Question: Are the areas of white chalky deposits illustrated schematically?

Answer: no


Question: What is characterized by an inflammatory infiltrate rich in eosinophils,  neutrophils,  and T cells?

Answer: the late-phase reaction


Question: What is the late-phase reaction characterized by?

Answer: an inflammatory infiltrate rich in eosinophils


Question: Is the immediate reaction characterized by an inflammatory infiltrate rich in eosinophils,  neutrophils,  and T cells?

Answer: no


Question: Is typical tuberculous granuloma showing an area of central necrosis characterized by an inflammatory infiltrate rich in eosinophils,  neutrophils,  and T cells?

Answer: no


Question: What is seen with antibodies against various nuclear antigens,  including Sm and RNPs?

Answer: a speckled pattern


Question: What is a speckled pattern seen with?

Answer: antibodies against various nuclear antigens


Question: Is a speckled pattern seen with antibodies against various nuclear antigens,  including Sm and RNPs?

Answer: yes


Question: Is failure to stain seen with antibodies against various nuclear antigens,  including Sm and RNPs?

Answer: no


Question: Is immunoperoxidase staining seen with antibodies against various nuclear antigens,  including Sm and RNPs?

Answer: no


Question: Is the wall of the artery seen with antibodies against various nuclear antigens,  including Sm and RNPs?

Answer: no


Question: Is Margin P seen with antibodies against various nuclear antigens,  including Sm and RNPs?

Answer: no


Question: What is seen in some cases of systemic sclerosis,  Sjogren syndrome,  and other diseases?

Answer: the pattern of staining of anti-centromere antibodies diseases


Question: Is the pattern of staining of anti-centromere antibodies seen in some cases of systemic sclerosis,  Sjogren syndrome,  and other diseases?

Answer: yes


Question: Is the principal cellular alterations that characterize reversible cell injury and necrosis seen in some cases of systemic sclerosis,  Sjogren syndrome,  and other diseases?

Answer: no


Question: Are neutrophils seen in some cases of systemic sclerosis,  Sjogren syndrome,  and other diseases?

Answer: no


Question: Is the dark green polypeptides seen in some cases of systemic sclerosis,  Sjogren syndrome,  and other diseases?

Answer: no


Question: Are genes that encode several proteins involved in antigen processing seen in some cases of systemic sclerosis,  Sjogren syndrome,  and other diseases?

Answer: no


Question: What corresponds to wire loops seen by light microscopy?

Answer: subendothelial dense deposits


Question: What do subendothelial dense deposits correspond to?

Answer: wire loops seen by light microscopy


Question: Do subendothelial dense deposits correspond to wire loops seen by light microscopy?

Answer: yes


Question: Do thrombus in the left and right ventricular apices correspond to wire loops seen by light microscopy?

Answer: no


Question: Does methylation of particular histone residues  correspond to wire loops seen by light microscopy?

Answer: no


Question: How is extracapillary proliferation?

Answer: not prominent in this case


Question: Is extracapillary proliferation not prominent in this case?

Answer: yes


Question: Is the embolus not prominent in this case?

Answer: no


Question: Is atrophy of the brain not prominent in this case?

Answer: no


Question: What is detected by immunofluorescence?

Answer: deposition of igg antibody


Question: What is deposition of IgG antibody in a granular pattern detected by?

Answer: immunofluorescence


Question: How is deposition of IgG antibody in a granular pattern detected?

Answer: by immunofluorescence


Question: Is deposition of IgG antibody in a granular pattern detected by immunofluorescence?

Answer: yes


Question: Is the immediate vascular and smooth muscle reaction to allergen detected by immunofluorescence?

Answer: no


Question: What shows liquefactive degeneration of the basal layer of the epidermis and edema at the dermoepidermal junction?

Answer: an h&e-stained section


Question: What does an H&E-stained section show of the basal layer of the epidermis and edema at the dermoepidermal junction?

Answer: liquefactive degeneration


Question: Does an H&E-stained section show liquefactive degeneration of the basal layer of the epidermis and edema at the dermoepidermal junction?

Answer: yes


Question: Does the immediate reaction show liquefactive degeneration of the basal layer of the epidermis and edema at the dermoepidermal junction?

Answer: no


Question: Does the remote kidney infarct show liquefactive degeneration of the basal layer of the epidermis and edema at the dermoepidermal junction?

Answer: no


Question: What is manifested by inflammatory cells in the inter-stitium and between epithelial cells of the tubules tubulitis?

Answer: acute cellular rejection of a kidney graft


Question: What is acute cellular rejection of a kidney graft manifested by in the inter-stitium and between epithelial cells of the tubules tubulitis?

Answer: inflammatory cells in the inter-stitium and between epithelial cells of the tubules tubulitis


Question: How is acute cellular rejection of a kidney graft manifested?

Answer: by inflammatory cells in the inter-stitium and between epithelial cells of the tubules tubulitis


Question: Is acute cellular rejection of a kidney graft manifested by inflammatory cells in the inter-stitium and between epithelial cells of the tubules tubulitis?

Answer: yes


Question: Is periodic acid-schiff manifested by inflammatory cells in the inter-stitium and between epithelial cells of the tubules tubulitis?

Answer: no


Question: What are outlined by wavy basement membranes?

Answer: collapsed tubules


Question: What are collapsed  tubules outlined by?

Answer: wavy basement membranes


Question: Are collapsed tubules outlined by wavy basement membranes?

Answer: yes


Question: Are t_h17 cells in granuloma formation outlined by wavy basement membranes?

Answer: no


Question: What is shown with inflammatory cells attacking and undermining the endothelium?

Answer: an arteriole


Question: What is an arteriole shown with?

Answer: inflammatory cells


Question: Is an arteriole shown with inflammatory cells attacking and undermining the endothelium arrow?

Answer: yes


Question: Is a section of an involved lacrimal gland shown with inflammatory cells attacking and undermining the endothelium arrow?

Answer: no


Question: What shows inflammatory cells within the capillary loops glomerulitis,  accumulation of mesangial matrix,  and duplication of the capillary basement membrane?

Answer: the glomerulus


Question: What does the glomerulus show within the capillary loops glomerulitis,  accumulation of mesangial matrix,  and duplication of the capillary basement membrane?

Answer: inflammatory cells


Question: Does the glomerulus show inflammatory cells within the capillary loops glomerulitis,  accumulation of mesangial matrix,  and duplication of the capillary basement membrane?

Answer: yes


Question: Does the extensive subcutaneous fibrosis show inflammatory cells within the capillary loops glomerulitis,  accumulation of mesangial matrix,  and duplication of the capillary basement membrane?

Answer: no


Question: What do interstitial fibrosis and tubular atrophy result from?

Answer: arteriosclerosis of arteries and arterioles in a chronically rejecting kidney allograft


Question: Do interstitial fibrosis and tubular atrophy result from arteriosclerosis of arteries and arterioles in a chronically rejecting kidney allograft?

Answer: yes


Question: Does a speckled pattern result from arteriosclerosis of arteries and arterioles in a chronically rejecting kidney allograft?

Answer: no


Question: What shows fibrosis in this trichrome stain?

Answer: the blue area


Question: What does the blue area show in this trichrome stain,  contrasted with the normal kidney (top right)?

Answer: fibrosis


Question: Does the blue area show fibrosis,  contrasted with the normal kidney right in this trichrome stain?

Answer: yes


Question: Does the tissue factor show fibrosis,  contrasted with the normal kidney right in this trichrome stain?

Answer: no


Question: What is shown (bottom right)?

Answer: an artery showing prominent arteriosclerosis


Question: Is an artery showing prominent arteriosclerosis shown (bottom right)?

Answer: yes


Question: Is the embolus shown (bottom right)?

Answer: no


Question: What shows apple-green birefringence under polarized light,  a diagnostic feature of amyloid?

Answer: congo red staining


Question: What does Congo red staining show under polarized light,  a diagnostic feature of amyloid?

Answer: apple-green birefringence


Question: Does Congo red staining show apple-green birefringence under polarized light,  a diagnostic feature of amyloid?

Answer: yes


Question: Does ischemic injury showing surface blebs show apple-green birefringence under polarized light,  a diagnostic feature of amyloid?

Answer: no


Question: What reveals pink-red deposits of amyloid in the walls of blood vessels and along sinusoids?

Answer: a section liver stained with congo


Question: What does a section of liver stained with Congo red reveal in the walls of blood vessels and along sinusoids?

Answer: pink-red deposits amyloid


Question: Does a section of liver stained with Congo red reveal pink-red deposits of amyloid in the walls of blood vessels and along sinusoids?

Answer: yes


Question: Does graft damage reveal pink-red deposits of amyloid in the walls of blood vessels and along sinusoids?

Answer: no


Question: What are presented in this field?

Answer: small nests of epithelial cells and myxoid stroma forming cartilage and bone


Question: What are small nests of epithelial cells and myxoid stroma forming?

Answer: cartilage and bone


Question: Are small nests of epithelial cells and myxoid stroma forming cartilage and bone presented in this field?

Answer: yes


Question: Are cm presented in this field?

Answer: no


Question: What shows cellular and nuclear variation in size and shape?

Answer: anaplastic tumor cells


Question: Does high-power detailed view of anaplastic tumor cells show cellular and nuclear variation in size and shape?

Answer: yes


Question: Do the majority of tissue macrophages show cellular and nuclear variation in size and shape?

Answer: no


Question: What has an abnormal tripolar spindle?

Answer: the prominent cell in the center field


Question: What does the prominent cell in the center field have?

Answer: an abnormal tripolar spindle


Question: Does the prominent cell in the center field have an abnormal tripolar spindle?

Answer: yes


Question: Does the graft damage have an abnormal tripolar spindle?

Answer: no


Question: What is replaced by atypical dysplastic cells?

Answer: the entire thickness of the epithelium cells


Question: What is the entire thickness of the epithelium replaced by?

Answer: atypical dysplastic cells


Question: Is the entire thickness of the epithelium replaced by atypical dysplastic cells?

Answer: yes


Question: Is the transmural light area in the posterolateral left ventricle replaced by atypical dysplastic cells?

Answer: no


Question: What shows that the entire thickness of the epithelium is replaced by atypical dysplastic cells?

Answer: the low-power view


Question: Does the low-power view show that the entire thickness of the epithelium is replaced by atypical dysplastic cells?

Answer: yes


Question: Do interstitial fibrosis and tubular atrophy show that the entire thickness of the epithelium is replaced by atypical dysplastic cells?

Answer: no


Question: What is orderly differentiation of squamous cells?

Answer: no


Question: Is there orderly differentiation of squamous cells?

Answer: no


Question: Is Margin P orderly differentiation of squamous cells?

Answer: no


Question: What is there in the subepithelial stroma?

Answer: no tumor


Question: Is there no tumor in the subepithelial stroma?

Answer: yes


Question: Is the section of an involved lacrimal gland no tumor in the subepithelial stroma?

Answer: no


Question: What is intact?

Answer: the basement membrane


Question: Is the basement membrane intact?

Answer: yes


Question: Is the prominent cell in the center field intact?

Answer: no


Question: What is sharply demarcated from the whiter breast tissue?

Answer: the tan-colored


Question: What is the tan-colored,  encapsulated small tumor demarcated from?

Answer: the whiter breast tissue


Question: Is the tan-colored,  encapsulated small tumor sharply demarcated from the whiter breast tissue?

Answer: yes


Question: Is the congo red staining sharply demarcated from the whiter breast tissue?

Answer: no


Question: What is studded with metastatic cancer?

Answer: a liver


Question: What is a liver studded with?

Answer: metastatic cancer


Question: How is a liver studded?

Answer: with metastatic cancer


Question: Is a liver studded with metastatic cancer?

Answer: yes


Question: Is the late-phase reaction studded with metastatic cancer?

Answer: no


Question: Are large,  flat cells with small nuclei typical?

Answer: yes


Question: Are two small pulmonary arterioles typical?

Answer: no


Question: How many cells are in mitosis?

Answer: one


Question: What is in mitosis?

Answer: one cell


Question: Are numerous friable mural thrombi in mitosis?

Answer: no


Question: Is nuclear pleomorphism evident?

Answer: yes


Question: Is atrophy of the brain evident?

Answer: no


Question: Are a few interspersed neutrophils,  much smaller in size and with compact,  lobate nuclei,  seen?

Answer: yes


Question: What is being utilized to identify mutations that can be targeted by drugs?

Answer: genetic analysis of cancers


Question: What is genetic analysis of cancers being utilized to do?

Answer: to identify mutations that can be targeted by drugs


Question: Is genetic analysis of cancers being utilized to identify mutations that can be targeted by drugs?

Answer: yes


Question: Are the necrotic cells being utilized to identify mutations that can be targeted by drugs?

Answer: no


Question: What are apparent?

Answer: extensive mucous plugging and dilation of the tracheobronchial tree


Question: Are extensive mucous plugging and dilation of the tracheobronchial tree apparent?

Answer: yes


Question: Are low-power view of a thrombosed artery apparent?

Answer: no


Question: What is the product of Pseudomonas infections?

Answer: greenish discoloration


Question: What is the greenish discoloration?

Answer: the product of pseudomonas infections


Question: Is the greenish discoloration the product of Pseudomonas infections?

Answer: yes


Question: Is collagen the product of Pseudomonas infections?

Answer: no


Question: What is consolidated by a combination of both secretions and pneumonia?

Answer: the pulmonary parenchyma


Question: What is the pulmonary parenchyma consolidated by?

Answer: the combination of both secretions and pneumonia


Question: Is the pulmonary parenchyma consolidated by a combination of both secretions and pneumonia?

Answer: yes


Question: Is numerous friable mural thrombi consolidated by a combination of both secretions and pneumonia?

Answer: no


Question: What has obvious lipid vacuolation under the light microscope?

Answer: a large neuron


Question: Does a large neuron have obvious lipid vacuolation under the light microscope?

Answer: yes


Question: Does reversibly injured myocardium have obvious lipid vacuolation under the light microscope?

Answer: no


Question: What shows prominent lysosomes with whorled configurations just below part of the nucleus?

Answer: a portion of a neuron under the electron microscope


Question: What does a portion of a neuron under the electron microscope show?

Answer: prominent lysosomes with whorled configurations just below part of the nucleus


Question: Does a portion of a neuron under the electron microscope show prominent lysosomes with whorled configurations just below part of the nucleus?

Answer: yes


Question: Does immunoperoxidase show prominent lysosomes with whorled configurations just below part of the nucleus?

Answer: no


Question: What have a foamy,  vacuolated appearance resulting from deposition of lipids?

Answer: the hepatocytes and kupffer cells


Question: What do the hepatocytes and Kupffer cells have resulting from deposition of lipids?

Answer: a foamy


Question: Do the hepatocytes and Kupffer cells have a foamy,  vacuolated appearance resulting from deposition of lipids?

Answer: yes


Question: What are electron micrograph of Gaucher cells with?

Answer: elongated distended lysosomes


Question: Is electron micrograph of Gaucher cells with elongated distended lysosomes?

Answer: yes


Question: What are fused or ill-formed?

Answer: the midface structures


Question: Are the midface structures fused or ill-formed?

Answer: yes


Question: What is associated with a lethal malformation,  in which the midface structures are fused or ill-formed?

Answer: stillbirth


Question: What is stillbirth associated with,  in which the midface structures are fused or ill-formed?

Answer: a lethal malformation


Question: How is stillbirth associated?

Answer: with a lethal malformation


Question: Is stillbirth associated with a lethal malformation,  in which the midface structures are fused or ill-formed?

Answer: yes


Question: Is the granuloma in the center associated with a lethal malformation,  in which the midface structures are fused or ill-formed?

Answer: no


Question: What is associated with severe internal anomalies such as maldevelopment of the brain and cardiac defects in almost all cases?

Answer: this degree of external dysmorphogenesis


Question: What is this degree of external dysmorphogenesis associated with?

Answer: severe internal anomalies


Question: Is this degree of external dysmorphogenesis associated with severe internal anomalies such as maldevelopment of the brain and cardiac defects in almost all cases?

Answer: yes


Question: Is atrophy associated with severe internal anomalies such as maldevelopment of the brain and cardiac defects in almost all cases?

Answer: no


Question: What extends from the portion of the amniotic sac to encircle the leg of the fetus?

Answer: the band of amnion


Question: What does the band of amnion extend from ?

Answer: the portion of the amniotic sac to encircle the leg of the fetus


Question: Does the band of amnion extend from the portion of the amniotic sac to encircle the leg of the fetus?

Answer: yes


Question: Does the blue area extend from the portion of the amniotic sac to encircle the leg of the fetus?

Answer: no


Question: What is at the right, in the specimen shown?

Answer: the placenta


Question: Where is the placenta, in the specimen shown?

Answer: at the right


Question: Is the placenta at the right, in the specimen shown?

Answer: yes


Question: Is the cause of reversible injury at the right, in the specimen shown?

Answer: no


Question: What is hematoxylin-eosin stain?

Answer: hyaline membrane disease


Question: Is this hematoxylin-eosin stain?

Answer: yes


Question: Is this Hyaline membrane disease?

Answer: yes


Question: What implies impending perforation?

Answer: the entire small bowel was markedly distended and perilously thin


Question: What does this appearance imply?

Answer: impending perforation


Question: Does this appearance imply impending perforation?

Answer: yes


Question: Does atrophy imply impending perforation?

Answer: no


Question: What corresponds to areas of hemorrhagic infarction and transmural necrosis?

Answer: the congested portion of the ileum


Question: What does the congested portion of the ileum correspond to?

Answer: areas of hemorrhagic infarction and transmural necrosis


Question: Does the congested portion of the ileum correspond to areas of hemorrhagic infarction and transmural necrosis?

Answer: yes


Question: Does the b-cell antigen receptor complex correspond to areas of hemorrhagic infarction and transmural necrosis?

Answer: no


Question: What are scattered among mature hepatocytes in this histologic preparation from an infant with nonimmune hydrops fetalis?

Answer: numerous islands of  extramedullary hematopoiesis


Question: What are numerous islands of extramedullary hematopoiesis scattered among in this histologic preparation from an infant with nonimmune hydrops fetalis?

Answer: mature hepatocytes


Question: Are numerous islands of extramedullary hematopoiesis scattered among mature hepatocytes in this histologic preparation from an infant with nonimmune hydrops fetalis?

Answer: yes


Question: Are neutrophils scattered among mature hepatocytes in this histologic preparation from an infant with nonimmune hydrops fetalis?

Answer: no


Question: What is less developed in the neonatal period than it is in adulthood?

Answer: the blood-brain barrier


Question: Is the blood-brain barrier less developed in the neonatal period than it is in adulthood?

Answer: yes


Question: Are some long-lived resident tissue macrophages less developed in the neonatal period than they are in adulthood?

Answer: no


Question: What occurs because the blood-brain barrier is less developed in the neonatal period than it is in adulthood?

Answer: severe hyperbilirubinemia


Question: Does this occur because the blood-brain barrier is less developed in the neonatal period than it is in adulthood?

Answer: yes


Question: Does the cause of reversible injury occur because the blood-brain barrier is less developed in the neonatal period than it is in adulthood?

Answer: no


Question: What develop long-term neurologic sequelae?

Answer: infants who survive


Question: Do infants who survive develop long-term neurologic sequelae?

Answer: yes


Question: Does healthy neutrophils with nuclei develop long-term neurologic sequelae?

Answer: no


Question: What had undergone spontaneous regression?

Answer: congenital capillary hemangioma at birth and at 2 years of age after the lesion


Question: Had the congenital capillary hemangioma at birth after the lesion undergone spontaneous regression?

Answer: yes


Question: When did the congenital capillary hemangioma after the lesion undergone spontaneous regression?

Answer: at 2 years of age after the lesion


Question: What had the congenital capillary hemangioma at 2 years of age after the lesion undergone?

Answer: spontaneous regression


Question: Had the congenital capillary hemangioma at 2 years of age after the lesion undergone spontaneous regression?

Answer: yes


Question: Had thrombus in the left and right ventricular apices undergone spontaneous regression?

Answer: no


Question: What is composed of small cells embedded in a finely fibrillar matrix?

Answer: the tumor


Question: What is this tumor composed of?

Answer: small cells embedded in finely fibrillar matrix (neuropil)


Question: Is this tumor composed of small cells embedded in a finely fibrillar matrix?

Answer: yes


Question: Is the late-phase reaction composed of small cells embedded in a finely fibrillar matrix?

Answer: no


Question: What is seen in the upper right corner?

Answer: a homer-wright pseudorosette


Question: What is a Homer-Wright pseudorosette?

Answer: tumor cells arranged concentrically around central core of neuropil


Question: Is a Homer-Wright pseudorosette seen in the upper right corner?

Answer: yes


Question: Is deposition of antibody on endothelium and activation of complement seen in the upper right corner?

Answer: no


Question: What are characterized by clusters of large ganglion cells with vesicular nuclei and abundant eosinophilic cytoplasm arrow?

Answer: ganglioneuromas


Question: What are Ganglioneuromas characterized by?

Answer: clusters of large ganglion cells with vesicular nuclei and abundant eosinophilic cytoplasm


Question: Are Ganglioneuromas characterized by clusters of large ganglion cells with vesicular nuclei and abundant eosinophilic cytoplasm (arrow)?

Answer: yes


Question: Is a liver characterized by clusters of large ganglion cells with vesicular nuclei and abundant eosinophilic cytoplasm arrow?

Answer: no


Question: What are presented in the background stroma?

Answer: spindle-shaped schwann cells


Question: Are spindle-shaped Schwann cells present in the background stroma?

Answer: yes


Question: Are infants who survive presented in the background stroma?

Answer: no


Question: What is attached to the kidney?

Answer: neuroblastoma


Question: Is FISH using a fluorescein-labeled cosmid probe for N-myc on a tissue section containing neuroblastoma attached to the kidney?

Answer: yes


Question: Is spindle-shaped schwann cells attached to the kidney?

Answer: no


Question: What corresponds to amplified N-MYC in the form of homogeneously staining regions?

Answer: the neuroblastoma cells on the upper half of the photo with large areas of staining (yellow-green)


Question: What does this correspond to in the form of homogeneously staining regions?

Answer: amplified n-myc


Question: Does this correspond to amplified N-MYC in the form of homogeneously staining regions?

Answer: yes


Question: Does section of an involved lacrimal gland correspond to amplified N-MYC in the form of homogeneously staining regions?

Answer: no


Question: What show no nuclear staining and background cytoplasmic staining?

Answer: renal tubular epithelial cells


Question: What do renal tubular epithelial cells in the lower half of the photograph show ?

Answer: no nuclear staining and background (green) cytoplasmic staining


Question: Do renal tubular epithelial cells in the lower half of the photograph show no nuclear staining and background cytoplasmic staining?

Answer: yes


Question: Do the photomicrographs show no nuclear staining and background cytoplasmic staining?

Answer: no


Question: How many 22q13 signals are there?

Answer: two


Question: Are there two 22q13 signals?

Answer: yes


Question: How many chromosomes do not stain with the probe for 22q11 .2,  indicating a microdeletion in this region?

Answer: one


Question: What does not stain with the probe for 22q11 .2,  indicating a microdeletion in this region?

Answer: one of the two chromosomes


Question: What does one of the two chromosomes for 22q11 .2 not stain with?

Answer: the probe for 22q112


Question: Does one of the two chromosomes not stain with the probe for 22q11 .2,  indicating a microdeletion in this region?

Answer: yes


Question: What gives rise to the 22q11 .2 deletion syndrome (DiGeorge syndrome)?

Answer: this abnormality


Question: What does this abnormality give rise to?

Answer: the 22q112 deletion syndrome


Question: Does this abnormality give rise to the 22q11 .2 deletion syndrome DiGeorge syndrome?

Answer: yes


Question: Does sci transl give rise to the 22q11 .2 deletion syndrome DiGeorge syndrome?

Answer: no


Question: What has caused a marked increase in their radiodensity,  so that they are as radiopaque as the cortical bone?

Answer: impaired remodeling of calcified cartilage in the epiphyses (arrows) of the wrist


Question: Has impaired remodeling of calcified cartilage in the epiphyses of the wrist caused a marked increase in their radiodensity,  so that they are as radiopaque as the cortical bone?

Answer: yes


Question: Have large,  flat cells with small nuclei caused a marked increase in their radiodensity,  so that they are as radiopaque as the cortical bone?

Answer: no


Question: Impaired remodeling of calcified cartilage in the epiphyses of the wrist has caused a marked increase in whose radiodensity , so that they are as radiopaque as the cortical bone ?

Answer: their


Question: Are the bridging strands of fibrous tissues evident?

Answer: yes


Question: Are a few interspersed neutrophils,  much smaller in size and with compact,  lobate nuclei,  evident?

Answer: no


Question: What is produced by radiation therapy of the neck region?

Answer: vascular changes and fibrosis of salivary glands


Question: What is vascular changes and fibrosis of salivary glands produced by?

Answer: radiation therapy of the neck region


Question: How is vascular changes and fibrosis of salivary glands produced?

Answer: by radiation therapy of the neck region


Question: Are vascular changes and fibrosis of salivary glands produced by radiation therapy of the neck region?

Answer: yes


Question: Are bile duct cells and canals of hering produced by radiation therapy of the neck region?

Answer: no


Question: What is produced by radiation therapy of the neck region?

Answer: vascular changes and fibrosis of salivary glands


Question: What is vascular changes and fibrosis of salivary glands produced by?

Answer: radiation therapy of the neck region


Question: How is vascular changes and fibrosis of salivary glands produced?

Answer: by radiation therapy of the neck region


Question: Is vascular changes and fibrosis of salivary glands produced by radiation therapy of the neck region?

Answer: yes


Question: Is bile duct cells and canals of hering produced by radiation therapy of the neck region?

Answer: no


Question: What is produced by radiation therapy of the neck region?

Answer: bile duct cells and canals of hering


Question: What is vascular changes and fibrosis of salivary glands produced by?

Answer: radiation therapy of the neck region


Question: How is vascular changes and fibrosis of salivary glands produced?

Answer: by radiation therapy of the neck region


Question: Is vascular changes and fibrosis of salivary glands produced by radiation therapy of the neck region?

Answer: yes


Question: Is the alveolar spaces and blood vessels produced by radiation therapy of the neck region?

Answer: no


Question: What appears to be too large for the emaciated body?

Answer: the head


Question: What does the head appear to be?

Answer: too large for the emaciated body


Question: Does the head appear to be too large for the emaciated body?

Answer: yes


Question: Does genomic dna appear to be too large for the emaciated body?

Answer: no


Question: What shows generalized edema,  seen as ascites and puffiness of the face,  hands,  and legs?

Answer: the infant


Question: What does the infant show?

Answer: generalized edema


Question: Does the infant show generalized edema,  seen as ascites and puffiness of the face,  hands,  and legs?

Answer: yes


Question: What is bowing of legs the consequence of?

Answer: the formation of poorly mineralized bone in a child


Question: How did note bowing of legs as a consequence of the formation of poorly mineralize bone in a child?

Answer: with rickets


Question: Is bowing of legs a consequence of the formation of poorly mineralized bone in a child with rickets?

Answer: yes


Question: Did bile duct cells and canals of hering mineralize bone in a child with rickets?

Answer: no


Question: What show distinct nuclear inclusions?

Answer: infected cells


Question: What do infected cells show?

Answer: distinct nuclear and ill-defined cytoplasmic


Question: Do infected cells show distinct nuclear inclusions?

Answer: yes


Question: Do energy stores show distinct nuclear inclusions?

Answer: no


Question: What show diffuse granular cyto-plasm,  reflecting accumulated hepatitis B surface antigen HBsAg in chronic infections?

Answer: infected hepatocytes


Question: What do infected hepatocytes show,  reflecting accumulated hepatitis B surface antigen HBsAg in chronic infections?

Answer: diffuse granular cyto-plasm


Question: Do infected hepatocytes show diffuse granular cyto-plasm,  reflecting accumulated hepatitis B surface antigen HBsAg in chronic infections?

Answer: yes


Question: Do those with tumors that had mycn amplification show diffuse granular cyto-plasm,  reflecting accumulated hepatitis B surface antigen HBsAg in chronic infections?

Answer: no


Question: Does gram stain preparation of a bronchoalveolar lavage specimen show gram-negative intracellular rods typical of members of Enterobacteriaceae such as Klebsiella pneumoniae or Escherichia coli?

Answer: yes


Question: Does collagen stain preparation of a bronchoalveolar lavage specimen show gram-negative intracellular rods typical of members of Enterobacteriaceae such as Klebsiella pneumoniae or Escherichia coli?

Answer: no


Question: Is this silver stain preparation of brain tissue from a patient with Lyme disease meningoencephalitis?

Answer: yes


Question: Is a homer-wright pseudorosette stain preparation of brain tissue from a patient with Lyme disease meningoencephalitis?

Answer: no


Question: What is markedly narrowed?

Answer: the lumen


Question: Is the lumen markedly narrowed?

Answer: yes


Question: Is herpes simplex virus and varicella-zoster virus markedly narrowed?

Answer: no


Question: What is thickened with the deposition of amorphous proteinaceous material (hyalinized)?

Answer: the arteriolar wall


Question: What is the arteriolar wall thickened with?

Answer: the deposition of amorphous proteinaceous material


Question: Is the arteriolar wall thickened with the deposition of amorphous proteinaceous material hyalinized?

Answer: yes


Question: Is edema thickened with the deposition of amorphous proteinaceous material hyalinized?

Answer: no


Question: What is periodic acid-Schiff stain?

Answer: luminal obliteration


Question: What demonstrates intimal,  macrophage-derived foam cells ?

Answer: fatty streak in an experimental hypercholesterolemic rabbit


Question: Does the fatty streak in an experimental hypercholesterolemic rabbit demonstrate intimal,  macrophage-derived foam cells ?

Answer: yes


Question: Does the anomalous area demonstrate intimal,  macrophage-derived foam cells ?

Answer: no


Question: What shows the regular layered pattern of elastic tissue?

Answer: normal media for comparison


Question: What did the normal media show of elastic tissue?

Answer: regular layered pattern of elastic tissue


Question: Did the normal media for comparison show the regular layered pattern of elastic tissue?

Answer: yes


Question: Did the majority of tissue macrophages show the regular layered pattern of elastic tissue?

Answer: no


Question: What is stained black in the figure?

Answer: elastin


Question: Is elastin stained black in the figure?

Answer: yes


Question: Is this stained black in the figure?

Answer: no


Question: What is filled by a large,  layered thrombus?

Answer: the lumen


Question: What is the lumen filled by?

Answer: a large


Question: Is the lumen filled by a large,  layered thrombus?

Answer: yes


Question: Is the areas of white chalky deposits filled by a large,  layered thrombus?

Answer: no


Question: What is attenuated?

Answer: the wall of the aneurysm


Question: Is the wall of the aneurysm attenuated?

Answer: yes


Question: Is acute cellular rejection of a kidney graft attenuated?

Answer: no


Question: What lies at the edge of a large area of atherosclerosis,  which arrested the propagation of the dissection?

Answer: the distal edge of the intramural hematoma


Question: Does the distal edge of the intramural hematoma lie at the edge of a large area of atherosclerosis,  which arrested the propagation of the dissection?

Answer: yes


Question: Does stillbirth lie at the edge of a large area of atherosclerosis,  which arrested the propagation of the dissection?

Answer: no


Question: What is red in this section,  stained with Movat stain?

Answer: blood


Question: Where is red blood,  stained with Movat stain?

Answer: in this section


Question: Is blood red in this section,  stained with Movat stain?

Answer: yes


Question: Is sci transl red in this section,  stained with Movat stain?

Answer: no


Question: Are black Aortic elastic layers, and red blood in this section, stained with Movat stain?

Answer: yes


Question: Are aortic elastic layers black?

Answer: yes


Question: What is shown in the figure demonstrating marked intimal thickening and luminal narrowing?

Answer: cross-sections of right carotid artery from the patient


Question: What did cross-sections of the right carotid artery from the patient shown in the figure demonstrate?

Answer: marked intimal thickening and luminal narrowing


Question: Do the cross-sections of the right carotid artery from the patient shown in the figure demonstrate marked intimal thickening and luminal narrowing?

Answer: yes


Question: Do the histone subunits shown in the figure demonstrate marked intimal thickening and luminal narrowing?

Answer: no


Question: What is the area of intimal hyperplasia?

Answer: the inner core of tan tissue


Question: What is the inner core of tan tissue?

Answer: the area of intimal hyperplasia


Question: Is the inner core of tan tissue the area of intimal hyperplasia?

Answer: yes


Question: Is the b-cell antigen receptor complex the area of intimal hyperplasia?

Answer: no


Question: What correspond to the original vessel wall?

Answer: the white circles


Question: What do the white circles correspond to?

Answer: the original vessel wall


Question: Do the white circles correspond to the original vessel wall?

Answer: yes


Question: Do small intestine stem cells correspond to the original vessel wall?

Answer: no


Question: What are those of acute inflammation and capillary proliferation?

Answer: histologic features


Question: What are histologic features?

Answer: acute inflammation and capillary proliferation


Question: Are histologic features those of acute inflammation and capillary proliferation?

Answer: yes


Question: Are numerous islands of extramedullary hematopoiesis those of acute inflammation and capillary proliferation?

Answer: no


Question: What demonstrates clusters of tangled bacilli (black)?

Answer: modified silver (warthin-starry) stain


Question: What does modified silver stain demonstrate?

Answer: clusters of tangled bacilli


Question: Does modified silver stain demonstrate clusters of tangled bacilli (black)?

Answer: yes


Question: Does the inner core of tan tissue demonstrate clusters of tangled bacilli (black)?

Answer: no


Question: What shows a thickened neointima overlying the stent wires black diamond encroaches on the lumen asterisk?

Answer: histologic view


Question: What does the histologic view show overlying the stent wires (black diamond indicated by the arrow), which encroaches on the lumen (asterisk)?

Answer: a thickened neointima


Question: Does the histologic view show a thickened neointima overlying the stent wires (black diamond indicated by the arrow), which encroaches on the lumen (asterisk)?

Answer: yes


Question: Does ischemic injury showing surface blebs show a thickened neointima overlying the stent wires black diamond encroaches on the lumen asterisk?

Answer: no


Question: What is a segmental narrowing of the aorta?

Answer: coarctation


Question: What is the coarctation of the aorta?

Answer: segmental narrowing


Question: Is the coarctation a segmental narrowing of the aorta?

Answer: yes


Question: Is schematic diagram of intimal thickening a segmental narrowing of the aorta?

Answer: no


Question: What manifest later in life than preductal coarctations?

Answer: lesions


Question: When do such lesions manifest than preductal coarctations?

Answer: later in life


Question: Do such lesions manifest later in life than preductal coarctations?

Answer: yes


Question: What are to the left of the coarctation?

Answer: the dilated ascending aorta and major branch vessels


Question: Where are the dilated ascending aorta and major branch vessels in relation to the coarctation?

Answer: to the left


Question: Are the dilated ascending aorta and major branch vessels to the left of the coarctation?

Answer: yes


Question: Are thrombus in the left and right ventricular apices to the left of the coarctation?

Answer: no


Question: What are perfused predominantly by way of dilated,  tortuous collateral channels?

Answer: the lower extremities


Question: What are the lower extremities perfused by?

Answer: by way of dilated


Question: Are the lower extremities perfused predominantly by way of dilated,  tortuous collateral channels?

Answer: yes


Question: Are two helical spirochetes perfused predominantly by way of dilated,  tortuous collateral channels?

Answer: no


Question: What is characterized by loose connective tissue and abundant capillaries?

Answer: granulation tissue


Question: What is granulation tissue characterized by?

Answer: loose connective and abundant capillaries


Question: How is granulation tissue characterized?

Answer: by loose connective and abundant capillaries


Question: Is granulation tissue characterized by loose connective tissue and abundant capillaries?

Answer: yes


Question: Is this tumor characterized by loose connective tissue and abundant capillaries?

Answer: no


Question: What are present?

Answer: a few residual cardiac muscle cells


Question: Are a few residual cardiac muscle cells present?

Answer: yes


Question: Are proadiposity signals present?

Answer: no


Question: Where is the posterior wall?

Answer: at the top


Question: Is the posterior wall at the top?

Answer: yes


Question: What have been distorted by the enlarged right ventricle?

Answer: the shape and volume of the left ventricle


Question: What have the shape and volume of the left ventricle been distorted by?

Answer: the enlarged right ventricle


Question: Have the shape and volume of the left ventricle been distorted by the enlarged right ventricle?

Answer: yes


Question: Has acute viral hepatitis been distorted by the enlarged right ventricle?

Answer: no


Question: How many cusps have a partial fusion at its center?

Answer: one


Question: What has a partial fusion at its center?

Answer: a cusp


Question: What does one cusp have at its center?

Answer: a partial fusion


Question: Does one cusp have a partial fusion at its center?

Answer: yes


Question: Does Margin P have a partial fusion at its center?

Answer: no


Question: One cusp has a partial fusion at whose center ?

Answer: its


Question: One cusp has a partial fusion at whose center ?

Answer: its


Question: Is there marked left atrial dilation as seen from above the valve?

Answer: yes


Question: Is high-power view of another region marked left atrial dilation as seen from above the valve?

Answer: no


Question: What is superimposed on chronic rheumatic heart disease?

Answer: acute rheumatic mitral valvulitis


Question: What is acute rheumatic mitral valvulitis superimposed on?

Answer: chronic rheumatic heart disease


Question: Is acute rheumatic mitral valvulitis superimposed on chronic rheumatic heart disease?

Answer: yes


Question: Is granulation tissue superimposed on chronic rheumatic heart disease?

Answer: no


Question: What are visible along the line of closure of the mitral valve leaflets?

Answer: small vegetations


Question: Where are small vegetations visible?

Answer: along the line of closure of the mitral valve leaflets


Question: Are small vegetations visible along the line of closure of the mitral valve leaflets?

Answer: yes


Question: Are others,  such as methylation of particular histone residues,  visible along the line of closure of the mitral valve leaflets?

Answer: no


Question: What have caused fibrous thickening and fusion of the chordae tendineae?

Answer: previous episodes of rheumatic valvulitis


Question: What have previous episodes of rheumatic valvulitis caused?

Answer: fibrous thickening and fusion of the chordae tendineae


Question: Have previous episodes of rheumatic valvulitis caused fibrous thickening and fusion of the chordae tendineae?

Answer: yes


Question: Have the effector arms of these central circuits caused fibrous thickening and fusion of the chordae tendineae?

Answer: no


Question: Does the inflammation resolve?

Answer: yes


Question: What is marked by the appearance of small,  warty,  inflammatory vegetations along the lines of valve closure?

Answer: the acute rheumatic fever phase of rheumatic heart disease (rhd)


Question: What is the acute rheumatic fever phase of rheumatic heart disease marked by ?

Answer: the appearance of small


Question: Is the acute rheumatic fever phase of rheumatic heart disease marked by the appearance of small,  warty,  inflammatory vegetations along the lines of valve closure?

Answer: yes


Question: Are some long-lived resident tissue macrophages marked by the appearance of small,  warty,  inflammatory vegetations along the lines of valve closure?

Answer: no


Question: What is characterized by large,  irregular,  often destructive masses that can extend from valve leaflets onto adjacent structures e.g.,  chordae or myocardium?

Answer: infective endocarditis (ie)


Question: What is infective endocarditis characterized by that can extend from valve leaflets onto adjacent structures e.g.,  chordae or myocardium?

Answer: large


Question: Is infective endocarditis characterized by large,  irregular,  often destructive masses that can extend from valve leaflets onto adjacent structures e.g.,  chordae or myocardium?

Answer: yes


Question: Are acute rheumatic mitral valvulitis characterized by large,  irregular,  often destructive masses that can extend from valve leaflets onto adjacent structures e.g.,  chordae or myocardium?

Answer: no


Question: What manifests with small - to medium-sized,  bland,  nondestructive vegetations at the line of valve closure?

Answer: non-bacterial thrombotic endocarditis (nbte)


Question: What does non-bacterial thrombotic endocarditis manifest with?

Answer: small- to medium-sized


Question: How does non-bacterial thrombotic endocarditis manifest?

Answer: with small- to medium-sized


Question: Does non-bacterial thrombotic endocarditis manifest with small - to medium-sized,  bland,  nondestructive vegetations at the line of valve closure?

Answer: yes


Question: Does one cusp manifest with small - to medium-sized,  bland,  nondestructive vegetations at the line of valve closure?

Answer: no


Question: What heals with scarring?

Answer: small- to medium-sized inflammatory vegetations caused by libman-sacks endocarditis (lse)


Question: Do these heal with scarring?

Answer: yes


Question: Do cohesive tumor in retina heal with scarring?

Answer: no


Question: What is characterized by small - to medium-sized inflammatory vegetations that can be attached on either side of the valve leaflets?

Answer: libman-sacks endocarditis (lse)


Question: Is Libman-Sacks endocarditis characterized by small - to medium-sized inflammatory vegetations that can be attached on either side of the valve leaflets?

Answer: yes


Question: Is homogeneous or diffuse staining of nuclei characterized by small - to medium-sized inflammatory vegetations that can be attached on either side of the valve leaflets?

Answer: no


Question: What is caused by staphylococcus aureus on a congenitally bicuspid aortic valve with extensive cuspal destruction and ring abscess?

Answer: acute endocarditis


Question: What is acute endocarditis caused by?

Answer: staphylococcus aureus on a congenitally bicuspid aortic valve with extensive cuspal destruction and ring abscess


Question: How is acute endocarditis caused?

Answer: by staphylococcus aureus on a congenitally bicuspid aortic valve with extensive cuspal destruction and ring abscess


Question: Is acute endocarditis caused by staphylococcus aureus on a congenitally bicuspid aortic valve with extensive cuspal destruction and ring abscess?

Answer: yes


Question: Is acid-fast caused by staphylococcus aureus on a congenitally bicuspid aortic valve with extensive cuspal destruction and ring abscess?

Answer: no


Question: What is only loosely attached to the cusp ?

Answer: the thrombus


Question: What is the thrombus  loosely attached to?

Answer: the cusp


Question: Is the thrombus only loosely attached to the cusp?

Answer: yes


Question: Is gram only loosely attached to the cusp?

Answer: no


Question: What is blue in this Masson trichrome-stained preparation?

Answer: collagen


Question: Is collagen blue in this Masson trichrome-stained preparation?

Answer: yes


Question: Is Margin P blue in this Masson trichrome-stained preparation?

Answer: no


Question: Does the congested portion of the ileum stain?

Answer: no


Question: What is markedly dilated with focal,  almost transmural replacement of the free wall by adipose tissue and fibrosis?

Answer: the right ventricle


Question: What is the right ventricle markedly dilated with?

Answer: focal


Question: Is the right ventricle markedly dilated with focal,  almost transmural replacement of the free wall by adipose tissue and fibrosis?

Answer: yes


Question: What has a grossly normal appearance in this heart?

Answer: the left ventricle


Question: What does the left ventricle have in this heart?

Answer: a grossly normal appearance


Question: Does the left ventricle have a grossly normal appearance in this heart?

Answer: yes


Question: Does fish use a fluorescein-labeled cosmid probe for n-myc on a tissue section containing neuroblastoma have a grossly normal appearance in this heart?

Answer: no


Question: Does the injurious stimulus have a grossly normal appearance in this heart?

Answer: no


Question: What is enlarged?

Answer: the left atrium


Question: Is the left atrium enlarged?

Answer: yes


Question: Is a liver enlarged?

Answer: no


Question: What bulges into the left ventricular outflow tract,  giving rise to a banana-shaped ventricular lumen?

Answer: the septal muscle


Question: Does the septal muscle bulge into the left ventricular outflow tract,  giving rise to a banana-shaped ventricular lumen?

Answer: yes


Question: Does acute endocarditis bulge into the left ventricular outflow tract,  giving rise to a banana-shaped ventricular lumen?

Answer: no


Question: What has been moved away from the septum to reveal a fibrous endocardial plaque?

Answer: the anterior mitral leaflet


Question: What has the anterior mitral leaflet been moved away from?

Answer: the septum


Question: Has the anterior mitral leaflet been moved away from the septum to reveal a fibrous endocardial plaque see text?

Answer: yes


Question: Has low-power view of a cross section of a skin blister showing the epidermis been moved away from the septum to reveal a fibrous endocardial plaque see text?

Answer: no


Question: What is present, along with mononuclear inflammation and myofiber necrosis?

Answer: a myofiber distended with trypanosomes


Question: What is a myofiber distended with trypanosomes presented along with?

Answer: mononuclear inflammation and myofiber necrosis


Question: Is a myofiber distended with trypanosomes present,  along with mononuclear inflammation and myofiber necrosis?

Answer: yes


Question: Are necrotic cells present,  along with mononuclear inflammation and myofiber necrosis?

Answer: no


Question: What shows sickle cells,  anisocytosis,  poikilocytosis,  and target cells?

Answer: low magnification


Question: What does low magnification show?

Answer: sickle cells


Question: Does low magnification show sickle cells,  anisocytosis,  poikilocytosis,  and target cells?

Answer: yes


Question: Does the cause of reversible injury show sickle cells,  anisocytosis,  poikilocytosis,  and target cells?

Answer: no


Question: What plucks out these inclusions?

Answer: splenic macrophages


Question: What do the splenic macrophages pluck out?

Answer: red cells with precipitates of denatured globin


Question: Do the splenic macrophages pluck out these inclusions?

Answer: yes


Question: Do the segregation of b cells and t cells in different regions of the lymph node pluck out these inclusions?

Answer: no


Question: Are bite cells similar to the one in this smear produced?

Answer: yes


Question: Are numerous islands of extramedullary hematopoiesis produced?

Answer: no


Question: What contains several fragmented red cells?

Answer: this specimen from patient with hemolytic uremic syndrome


Question: What does this specimen from a patient with hemolytic uremic syndrome contain?

Answer: several fragmented red cells


Question: Does this specimen from a patient with hemolytic uremic syndrome contain several fragmented red cells?

Answer: yes


Question: Do those with tumors that had mycn amplification contain several fragmented red cells?

Answer: no


Question: What stands out in contrast?

Answer: scattered


Question: Does scattered,  fully hemoglobinized cells,  from a recent blood transfusion,  stand out in contrast?

Answer: yes


Question: Do the principal cellular alterations that characterize reversible cell injury and necrosis stand out in contrast?

Answer: no


Question: What results for the ALL are shown in the figure?

Answer: flow cytometry


Question: Does the absence of staining result for the ALL shown in the figure?

Answer: no


Question: What are positive for the B cell markers CD19 and CD22?

Answer: the tumor cells


Question: Is CD10 a marker expressed on a subset of ALLs,  and TdT a specialized DNA polymerase that is expressed in pre-B and pre-T cells?

Answer: yes


Question: Are the tumor cells positive for the B cell markers CD19 and CD22 ?

Answer: yes


Question: Is this specimen from a patient with hemolytic uremic syndrome positive for the B cell markers CD19 and CD22 ?

Answer: no


Question: What shows diffuse effacement of nodal architecture?

Answer: low-power view


Question: Does the low-power view show diffuse effacement of nodal architecture?

Answer: yes


Question: Does the vessel wall show diffuse effacement of nodal architecture?

Answer: no


Question: What have the appearance of small,  round lymphocytes at high power?

Answer: a majority of tumor cells


Question: What appearance do a majority of the tumor cells have?

Answer: small


Question: Do a majority of the tumor cells have the appearance of small,  round lymphocytes at high power?

Answer: yes


Question: Do the photomicrographs have the appearance of small,  round lymphocytes at high power?

Answer: no


Question: What is present in this field?

Answer: a prolymphocyte


Question: What is a prolymphocyte?

Answer: a larger cell with a centrally placed nucleolus


Question: Is a prolymphocyte, a larger cell with a centrally placed nucleolus,  present in this field?

Answer: yes


Question: Is sci transl present in this field?

Answer: no


Question: What have large nuclei with open chromatin and prominent nucleoli?

Answer: the tumor cells


Question: What do the tumor cells have?

Answer: large nuclei with open chromatin and prominent nucleoli


Question: How do the tumor cells have large nuclei?

Answer: with open chromatin and prominent nucleoli


Question: Do the tumor cells have large nuclei with open chromatin and prominent nucleoli?

Answer: yes


Question: Do neutrophils have large nuclei with open chromatin and prominent nucleoli?

Answer: no


Question: Whose nuclei are fairly uniform,  giving a monotonous appearance?

Answer: the tumor cells


Question: What are fairly uniform,  giving a monotonous appearance?

Answer: the tumor cells and their nuclei


Question: How are the tumor cells and their nuclei?

Answer: fairly uniform


Question: Are the tumor cells and their nuclei fairly uniform,  giving a monotonous appearance?

Answer: yes


Question: Are the principal cellular alterations that characterize reversible cell injury and necrosis fairly uniform,  giving a monotonous appearance?

Answer: no


Question: What is produced by interspersed,  lightly staining, normal microphages?

Answer: the starry sky pattern


Question: How is the starry sky pattern produced?

Answer: by interspersed


Question: Is the starry sky pattern produced by interspersed,  lightly staining, normal microphages?

Answer: yes


Question: Are infective endocarditis produced by interspersed,  lightly staining, normal microphages?

Answer: no


Question: What is better appreciated at a lower magnification?

Answer: normal macrophages


Question: How is normal macrophages?

Answer: better appreciated at a lower magnification


Question: Are normal macrophages better appreciated at a lower magnification?

Answer: yes


Question: Are those with tumors that had mycn amplification better appreciated at a lower magnification?

Answer: no


Question: The tumor cells and whose nuclei are fairly uniform , giving a monotonous appearance ?

Answer: their


Question: What are most obvious in the calvaria?

Answer: the sharply punched-out bone defects


Question: Are the sharply punched-out bone defects most obvious in the calvaria?

Answer: yes


Question: Are t_h2 cells most obvious in the calvaria?

Answer: no


Question: What are largely replaced by plasma cells,  including atypical forms with multiple nuclei,  prominent nucleoli,  and cyto-plasmic droplets containing immunoglobulin?

Answer: normal marrow cells


Question: What are normal marrow cells cells replaced by?

Answer: plasma cells


Question: Are normal marrow cells largely replaced by plasma cells,  including atypical forms with multiple nuclei,  prominent nucleoli,  and cyto-plasmic droplets containing immunoglobulin?

Answer: yes


Question: Are the available anabolic circuits largely replaced by plasma cells,  including atypical forms with multiple nuclei,  prominent nucleoli,  and cyto-plasmic droplets containing immunoglobulin?

Answer: no


Question: What has abnormally coarse and numerous azurophilic granules?

Answer: neo-plastic promyelocytes


Question: Do the neo-plastic promyelocytes have abnormally coarse and numerous azurophilic granules?

Answer: yes


Question: What include a cell in the center of the field with multiple needlelike Auer rods?

Answer: other characteristic findings


Question: What do other characteristic findings include?

Answer: a cell in the center of the field with multiple needlelike auer rods


Question: Do other characteristic findings include a cell in the center of the field with multiple needlelike Auer rods?

Answer: yes


Question: Do infected cells include a cell in the center of the field with multiple needlelike Auer rods?

Answer: no


Question: What are present?

Answer: granulocytic forms at various stages of differentiation


Question: Are granulocytic forms at various stages of differentiation presented?

Answer: yes


Question: How many nucleated erythroid precursors are evident?

Answer: two


Question: How are two nucleated erythroid precursors and several teardrop-shaped red cells?

Answer: evident


Question: Are two nucleated erythroid precursors and several teardrop-shaped red cells evident?

Answer: yes


Question: What were present in other fields?

Answer: immature myeloid cells


Question: Were immature myeloid cells present in other fields?

Answer: yes


Question: Was a myofiber distended with trypanosomes present in other fields?

Answer: no


Question: What stimulates fibroblast growth and collagen deposition associated with the healing phase of injury?

Answer: the release of macrophage-derived fibrogenic cytokines


Question: Do the release of macrophage-derived fibrogenic cytokines such as transforming growth factor-beta stimulate fibroblast growth and collagen deposition associated with the healing phase of injury?

Answer: yes


Question: Do the dark green polypeptides stimulate fibroblast growth and collagen deposition associated with the healing phase of injury?

Answer: no


Question: What are distended?

Answer: other alveoli


Question: Are the principal cellular alterations that characterize reversible cell injury and necrosis distended?

Answer: no


Question: What are collapsed,  while others are distended?

Answer: some alveoli


Question: Are some alveoli collapsed,  while others are distended?

Answer: yes


Question: What are lined by bright pink hyaline membranes?

Answer: alveoli


Question: Is a prolymphocyte, a larger cell with a centrally placed nucleolus,  lined by bright pink hyaline membranes?

Answer: no


Question: What shows sub-basement membrane fibrosis,  eosinophilic inflammation, and smooth muscle hyperplasia?

Answer: the bronchial biopsy specimen


Question: What does the bronchial biopsy specimen from the asthmatic patient show?

Answer: sub-basement membrane fibrosis


Question: Does the bronchial biopsy specimen from an asthmatic patient show sub-basement membrane fibrosis,  eosinophilic inflammation?

Answer: yes


Question: Do renal tubular epithelial cells in the lower half of the photograph show sub-basement membrane fibrosis,  eosinophilic inflammation?

Answer: no


Question: What shows markedly dilated bronchi filled with purulent mucus that extend to subpleural regions?

Answer: cut surface of lung


Question: What does the cut surface of lung show?

Answer: markedly dilated bronchi filled with purulent mucus that extend to subpleural regions


Question: Does the cut surface of lung show markedly dilated bronchi filled with purulent mucus that extend to subpleural regions?

Answer: yes


Question: Does a diagnostic,  binucleate reed-sternberg cell show markedly dilated bronchi filled with purulent mucus that extend to subpleural regions?

Answer: no


Question: What is more pronounced in the subpleural region?

Answer: the fibrosis


Question: How is the fibrosis,  which varies in intensity?

Answer: more pronounced subpleural region


Question: Is the fibrosis,  which varies in intensity,  more pronounced in the subpleural region?

Answer: yes


Question: Is failure to stain more pronounced in the subpleural region?

Answer: no


Question: What is present to the left?

Answer: honey-combing


Question: Where is honey-combing present to?

Answer: left


Question: Is honey-combing present to the left?

Answer: yes


Question: Is schematic diagram of intimal thickening present to the left?

Answer: no


Question: What is associated with fibrosis?

Answer: a large amount of black pigment


Question: What is a large amount of black pigment associated with?

Answer: fibrosis


Question: Is a large amount of black pigment associated with fibrosis?

Answer: yes


Question: Is high-power view of another region associated with fibrosis?

Answer: no


Question: What has contracted the upper lobe into a small dark mass?

Answer: scarring


Question: What has scarring contracted into a small dark mass?

Answer: the upper lobe


Question: Has scarring contracted the upper lobe into a small dark mass?

Answer: yes


Question: Has the palisade of cartilage contracted the upper lobe into a small dark mass?

Answer: no


Question: What reveals the typical beading and knobbed ends?

Answer: high-power detail of an asbestos body


Question: Does the high-power detail of an asbestos body reveal the typical beading and knobbed ends?

Answer: yes


Question: Did fatty streak in an experimental hypercholesterolemic rabbit reveal the typical beading and knobbed ends?

Answer: no


Question: What are present?

Answer: characteristic peribronchial noncaseating granulomas with many giant cells


Question: Are characteristic peribronchial noncaseating granulomas with many giant cells present?

Answer: yes


Question: Are t_h 17 cells in granuloma formation present?

Answer: no


Question: Are loosely formed interstitial granulomas and chronic inflammation characteristic?

Answer: yes


Question: Are histologic features characteristic?

Answer: no


Question: Where is the accumulation of large numbers of macrophages?

Answer: within the alveolar spaces


Question: What is there of large numbers of macrophages within the alveolar spaces with only slight fibrous thickening of the alveolar walls?

Answer: accumulation of large numbers of macrophage


Question: Is there accumulation of large numbers of macrophages within the alveolar spaces with only slight fibrous thickening of the alveolar walls?

Answer: yes


Question: What has been stained with Prussian blue,  an iron stain that highlights the abundant intracellular hemo-siderin?

Answer: the tissue


Question: What has the tissue been stained with?

Answer: prussian blue


Question: Has the tissue been stained with Prussian blue,  an iron stain that highlights the abundant intracellular hemo-siderin?

Answer: yes


Question: Has the acute myocardial infarct of the posterolateral left ventricle been stained with Prussian blue,  an iron stain that highlights the abundant intracellular hemo-siderin?

Answer: no


Question: What is uniformly consolidated?

Answer: the lower lobe


Question: Is the lower lobe uniformly consolidated?

Answer: yes


Question: Is the left ventricle uniformly consolidated?

Answer: no


Question: What correspond to early red hepatization?

Answer: the congested septal capillaries and extensive neutrophil exudation into alveoli


Question: Do the congested septal capillaries and extensive neutrophil exudation into alveoli correspond to early red hepatization?

Answer: yes


Question: Do signals correspond to early red hepatization?

Answer: no


Question: What have not yet formed?

Answer: fibrin nets


Question: Have Fibrin nets not yet formed?

Answer: yes


Question: Have panels c and d not yet formed?

Answer: no


Question: Is early organization of intraalveolar exudate seen?

Answer: yes


Question: What is under the pleura in the lower part of the upper lobe?

Answer: the gray-white parenchymal focus


Question: Is the gray-white parenchymal focus under the pleura in the lower part of the upper lobe?

Answer: yes


Question: Is scarring under the pleura in the lower part of the upper lobe?

Answer: no


Question: What are seen left?

Answer: hilar lymph nodes with caseation


Question: Where are hilar lymph nodes with caseation seen?

Answer: on the left


Question: Are hilar lymph nodes with caseation seen left?

Answer: yes


Question: Are two helical spirochetes seen left?

Answer: no


Question: What are seen in this specimen from an immunosuppressed patient?

Answer: sheets of macrophages packed with mycobacteria


Question: What are sheets of macrophages packed with mycobacteria seen in?

Answer: a specimen from an immunosuppressed patient


Question: Are sheets of macrophages packed with mycobacteria seen in this specimen from an immunosuppressed patient?

Answer: yes


Question: Are the media of the artery seen in this specimen from an immunosuppressed patient?

Answer: no


Question: What are riddled with gray-white areas of caseation and multiple areas of softening and cavitation?

Answer: the upper parts of both lungs


Question: What are the upper parts of both lungs riddled with?

Answer: the gray-white areas of caseation and multiple areas of softening and cavitation


Question: Are the upper parts of both lungs riddled with gray-white areas of caseation and multiple areas of softening and cavitation?

Answer: yes


Question: Are the segregation of b cells and t cells in different regions of the lymph node riddled with gray-white areas of caseation and multiple areas of softening and cavitation?

Answer: no


Question: What shows numerous gray-white granulomas?

Answer: the cut surface


Question: Does the cut surface show numerous gray-white granulomas?

Answer: yes


Question: Does the congested portion of the ileum show numerous gray-white granulomas?

Answer: no


Question: What fills phagocytes in a lymph node of a patient with disseminated histoplasmosis?

Answer: histoplasma capsulatum yeast forms


Question: What do histoplasma capsulatum yeast forms fill?

Answer: phagocytes in the lymph node of a patient with disseminated histoplasmosis


Question: Do histoplasma capsulatum yeast forms fill phagocytes in a lymph node of a patient with disseminated histoplasmosis silver stain?

Answer: yes


Question: Does the bronchial biopsy specimen from an asthmatic patient fill phagocytes in a lymph node of a patient with disseminated histoplasmosis silver stain?

Answer: no


Question: What highlights the broad-based budding seen in Blastomyces immitis organisms?

Answer: silver stain


Question: What does silver stain highlight?

Answer: the broad-based budding seen in blastomyces immitis organisms


Question: Does silver stain highlight the broad-based budding seen in Blastomyces immitis organisms?

Answer: yes


Question: Does the absence of staining highlight the broad-based budding seen in Blastomyces immitis organisms?

Answer: no


Question: What are seen in an enlarged cell?

Answer: a distinct nuclear inclusion and multiple cytoplasmic inclusions


Question: What are a distinct nuclear inclusion and multiple cytoplasmic inclusions seen in?

Answer: an enlarged cell


Question: Are a distinct nuclear inclusion and multiple cytoplasmic inclusions seen in an enlarged cell?

Answer: yes


Question: Are the effector arms of these central circuits seen in an enlarged cell?

Answer: no


Question: What include the appearance of squamous dysplasia,  characterized by the presence of disordered squamous epithelium,  with loss of nuclear polarity,  nuclear hyperchromasia,  pleomorphism,  and mitotic figures?

Answer: more ominous changes


Question: What do more ominous changes include?

Answer: the appearance of squamous dysplasia


Question: Do more ominous changes include the appearance of squamous dysplasia,  characterized by the presence of disordered squamous epithelium,  with loss of nuclear polarity,  nuclear hyperchromasia,  pleomorphism,  and mitotic figures?

Answer: yes


Question: Do the midface structures include the appearance of squamous dysplasia,  characterized by the presence of disordered squamous epithelium,  with loss of nuclear polarity,  nuclear hyperchromasia,  pleomorphism,  and mitotic figures?

Answer: no


Question: What is the stage that immediately precedes invasive squamous cell carcinoma?

Answer: carcinoma in situ (cis)


Question: What is carcinoma in situ?

Answer: the stage that immediately precedes invasive squamous cell carcinoma


Question: Is carcinoma in situ the stage that immediately precedes invasive squamous cell carcinoma?

Answer: yes


Question: Is stillbirth the stage that immediately precedes invasive squamous cell carcinoma?

Answer: no


Question: What are similar to those in frank carcinoma, apart from the lack of basement membrane disruption in CIS?

Answer: the cytologic features of cis


Question: What are the cytologic features of CIS similar to?

Answer: those in frank carcinoma


Question: Are the cytologic features of CIS similar to those in frank carcinoma apart from the lack of basement membrane disruption in CIS?

Answer: yes


Question: Are a majority of the tumor cells similar to those in frank carcinoma apart from the lack of basement membrane disruption in CIS?

Answer: no


Question: What appears normal,  with a delicate basement membrane?

Answer: the silver methenamine-stained glomerulus


Question: What does the silver methenamine-stained glomerulus appear normal with?

Answer: a delicate basement membrane


Question: How does the silver methenamine-stained glomerulus appear ?

Answer: with a delicate basement membrane


Question: Does the silver methenamine-stained glomerulus appear normal,  with a delicate basement membrane?

Answer: yes


Question: Does a peripheral blood smear appear normal,  with a delicate basement membrane?

Answer: no


Question: Are the focal and segmental glomerulosclerosis (periodic acid-Schiff stain) seen as a collection of scarred,  obliterate capillaries and accumula-tions of matrix material in part of the affected glomerulus?

Answer: yes


Question: Is characteristic immunofluorescence deposition of IgA,  principally in mesangial regions,  evident?

Answer: yes


Question: Are a few residual cardiac muscle cells evident?

Answer: no


Question: Does normal media for comparison indicate areas of necrosis and crescent formation?

Answer: no


Question: What is typical of ANCA (anti-neutrophil cytoplasmic antibody)- associated crescentic glomerulonephritis?

Answer: the segmental distribution


Question: What is the segmental distribution in this case?

Answer: typical of anca (anti-neutrophil cytoplasmic antibody)- associated crescentic glomerulonephritis


Question: Is the segmental distribution in this case typical of ANCA (anti-neutrophil cytoplasmic antibody)- associated crescentic glomerulonephritis?

Answer: yes


Question: Is a characteristic tubercle at low magnification typical of ANCA anti-neutrophil cytoplasmic antibody - associated crescentic glomerulonephritis?

Answer: no


Question: What is relatively unaffected?

Answer: the lower pole


Question: Is the lower pole relatively unaffected?

Answer: yes


Question: Is the surrounding lung relatively unaffected?

Answer: no


Question: What is studded with focal pale abscesses,  more numerous in the upper pole and middle region of the kidney?

Answer: the cortical surface


Question: What is the cortical surface studded with?

Answer: focal pale abscesses


Question: Is the cortical surface studded with focal pale abscesses,  more numerous in the upper pole and middle region of the kidney?

Answer: yes


Question: Is acute coronary throm-bosis studded with focal pale abscesses,  more numerous in the upper pole and middle region of the kidney?

Answer: no


Question: What is there between the abscesses?

Answer: dark congestion of the renal surface


Question: Is there dark congestion of the renal surface between the abscesses?

Answer: yes


Question: Is acute rheumatic mitral valvulitis dark congestion of the renal surface between the abscesses?

Answer: no


Question: Whose underlying basement membranes is detachment of tubular cells from,  and granular casts?

Answer: their


Question: Does acute tubular epithelial cell injury with blebbing at the luminal pole,  detachment of tubular cells from their underlying basement membranes,  and granular cast?

Answer: yes


Question: Does homogeneous or diffuse staining of nuclei cast?

Answer: no


Question: Acute tubular epithelial cell injury with blebbing at the luminal pole , detachment of tubular cells from whose underlying basement membranes , and granular casts ?

Answer: their


Question: What is markedly enlarged?

Answer: the kidney


Question: Is the kidney markedly enlarged?

Answer: yes


Question: Is libman-sacks endocarditis markedly enlarged?

Answer: no


Question: What is shown for scale?

Answer: centimeter rule


Question: What is centimeter rule shown for?

Answer: scale


Question: Is centimeter rule shown for scale?

Answer: yes


Question: Is numerous friable mural thrombi shown for scale?

Answer: no


Question: What is markedly enlarged?

Answer: the kidney


Question: Is the kidney markedly enlarged?

Answer: yes


Question: Is remote kidney infarct markedly enlarged?

Answer: no


Question: What is striking?

Answer: the angiogram


Question: Is the angiogram striking?

Answer: yes


Question: Is the cut surface striking?

Answer: no


Question: What is more commonly used to identify varices?

Answer: endoscopy


Question: What is endoscopy more commonly used to?

Answer: identify varices


Question: Is endoscopy more commonly used to identify varices?

Answer: yes


Question: Is a uncleolar pattern more commonly used to identify varices?

Answer: no


Question: What are present in this postmortem specimen corresponding to the angiogram in the figure?

Answer: collapsed varices


Question: Where are collapsed varices present?

Answer: in the postmortem specimen


Question: Are collapsed varices present in this postmortem specimen corresponding to the angiogram in the figure?

Answer: yes


Question: Are histoplasma capsulatum yeast forms present in this postmortem specimen corresponding to the angiogram in the figure?

Answer: no


Question: What are sites of variceal hemorrhage that were ligated with bands?

Answer: the polypoid areas


Question: What are the polypoid areas?

Answer: the sites of variceal hemorrhage that were ligated with bands


Question: Are the polypoid areas sites of variceal hemorrhage that were ligated with bands?

Answer: yes


Question: Are varices sites of variceal hemorrhage that were ligated with bands?

Answer: no


Question: What reveals circumferential rings in the proximal esophagus of this patient with eosinophilic esophagitis?

Answer: endoscopy


Question: What does endoscopy reveal?

Answer: circumferential rings in the proximal esophagus


Question: Does endoscopy reveal circumferential rings in the proximal esophagus of this patient with eosinophilic esophagitis?

Answer: yes


Question: Does the atrium reveal circumferential rings in the proximal esophagus of this patient with eosinophilic esophagitis?

Answer: no


Question: What are characteristic of H. pylori gastritis?

Answer: lymphoid aggregates with germinal centers and abundant subepithelial plasma cells within the superficial lamina propria


Question: What are lymphoid aggregates with germinal centers and abundant subepi-thelial plasma cells within the superficial lamina propria?

Answer: characteristics of h pylori gastritis


Question: Are lymphoid aggregates with germinal centers and abundant subepi-thelial plasma cells within the superficial lamina propria characteristic of H. pylori gastritis?

Answer: yes


Question: Is a distinct nuclear inclusion and multiple cytoplasmic inclusions characteristic of H. pylori gastritis?

Answer: no


Question: What is associated with NSAID use?

Answer: typical antral ulcer


Question: What is endoscopic view of typical antral ulcer associated with?

Answer: nsaid use


Question: How is endoscopic view of typical antral ulcer associated?

Answer: with nsaid use


Question: Is the antral ulcer associated with NSAID use?

Answer: yes


Question: Is the high-power detail of an asbestos body associated with NSAID use?

Answer: no


Question: What form a submucosal nodule composed of tumor cells embedded in dense fibrous tissue?

Answer: carcinoid tumors


Question: What do carcinoid tumors form?

Answer: a submucosal nodule


Question: Do carcinoid tumors form a submucosal nodule composed of tumor cells embedded in dense fibrous tissue?

Answer: yes


Question: Do the cytologic features of cis form a submucosal nodule composed of tumor cells embedded in dense fibrous tissue?

Answer: no


Question: What shows the bland cytology that typifies neuroendocrine tumors?

Answer: high magnification


Question: What does high magnification show?

Answer: the bland cytology that typifies neuroendocrine tumors


Question: Does high magnification show the bland cytology that typifies neuroendocrine tumors?

Answer: yes


Question: Does granulomatous host response show the bland cytology that typifies neuroendocrine tumors?

Answer: no


Question: What assumes a salt-and-pepper pattern?

Answer: the chromatin texture


Question: What is the appearance of the chromatin texture,  with fine and coarse clumps?

Answer: a salt-and-pepper pattern


Question: Does the chromatin texture,  with fine and coarse clumps,  assume a salt-and-pepper pattern?

Answer: yes


Question: Do neutrophils assume a salt-and-pepper pattern?

Answer: no


Question: What were absent in the rectum,  presented in the sigmoid colon?

Answer: ganglion cells


Question: Where were ganglion cells absent?

Answer: in the rectum


Question: Were ganglion cells absent in the rectum,  but presented in the sigmoid colon?

Answer: yes


Question: Were all three transverse sections of myocardium absent in the rectum,  but presented in the sigmoid colon?

Answer: no


Question: Whose densely stained nuclei (labeled T) are shown?

Answer: t lymphocytes


Question: What can infiltration of the surface epithelium by T lymphocytes be recognized by?

Answer: densely stained nuclei


Question: Can infiltration of the surface epithelium by T lymphocytes be recognized by their densely stained nuclei?

Answer: yes


Question: Infiltration of the surface epithelium by T lymphocytes , which can be recognized by whose stained nuclei labeled T ?

Answer: their


Question: What produces acute,  self-limited colitis?

Answer: campylobacter jejuni infection


Question: What does Campylobacter jejuni infection produce?

Answer: acute


Question: Does Campylobacter jejuni infection produce acute,  self-limited colitis?

Answer: yes


Question: Does the wall of the aneurysm produce acute,  self-limited colitis?

Answer: no


Question: What is presented lower right?

Answer: a crypt abscess


Question: Is a crypt abscess present in the lower right?

Answer: yes


Question: What is similar to other acute,  self-limited colitides?

Answer: enteroinvasive escherichia coli infection


Question: How is Enteroinvasive Escherichia coli infection?

Answer: similar to other acute


Question: Is Enteroinvasive Escherichia coli infection similar to other acute,  self-limited colitides?

Answer: yes


Question: What is coated by tan pseudomembranes composed of neutrophils,  dead epithelial cells,  and inflammatory debris endoscopic view?

Answer: the colon


Question: What is the colon coated by?

Answer: tan pseudomembranes


Question: Is the colon coated by tan pseudomembranes composed of neutrophils,  dead epithelial cells,  and inflammatory debris endoscopic view?

Answer: yes


Question: Is a pacemaker coated by tan pseudomembranes composed of neutrophils,  dead epithelial cells,  and inflammatory debris endoscopic view?

Answer: no


Question: What is reminiscent of a volcanic eruption?

Answer: typical pattern of neutrophils emanating from crypt


Question: Where are the neutrophils emanating from?

Answer: the crypt


Question: Is the typical pattern of neutrophils emanating from a crypt reminiscent of a volcanic eruption?

Answer: yes


Question: Is the normal media for comparison reminiscent of a volcanic eruption?

Answer: no


Question: What results from repeated injury and regeneration?

Answer: haphazard crypt organization


Question: What does haphazard crypt organization result from?

Answer: repeated injury and regeneration


Question: Does haphazard crypt organization result from repeated injury and regeneration?

Answer: yes


Question: Does the head result from repeated injury and regeneration?

Answer: no


Question: What are at the periphery?

Answer: portal tracts


Question: Where are the portal tracts?

Answer: at the periphery


Question: Are the portal tracts at the periphery?

Answer: yes


Question: Are areas of chalky necrosis at the periphery?

Answer: no


Question: What is at the center of a lobule, while the portal tracts are at the periphery in the lobular model?

Answer: the terminal hepatic vein


Question: Where is the terminal hepatic vein in the lobular model?

Answer: at the center of the lobule


Question: Is the terminal hepatic vein at the center of a lobule, while the portal tracts are at the periphery in the lobular model?

Answer: yes


Question: Is remote kidney infarct at the center of a lobule, while the portal tracts are at the periphery in the lobular model?

Answer: no


Question: Who often refers to the regions of the parenchyma as periportal and centrilobular?

Answer: pathologists


Question: How do pathologists refer to the regions of the parenchyma?

Answer: as periportal and centrilobular


Question: Do pathologists refer to the regions of the parenchyma as periportal and centrilobular?

Answer: yes


Question: Do histologic appearance in active takayasu aortitis illustrating destruction and fibrosis of the arterial media refer to the regions of the parenchyma as periportal and centrilobular?

Answer: no


Question: What is the farthest?

Answer: zone 3


Question: Is zone 3 the farthest?

Answer: yes


Question: Is a large amount of black pigment the farthest?

Answer: no


Question: When are most scars gone Masson trichrome stain?

Answer: after abstinence


Question: When are most scars gone Masson trichrome stain?

Answer: after 1 year of abstinence


Question: What are gone after 1 year of abstinence?

Answer: most scars


Question: When are most scars gone?

Answer: after 1 year of abstinance


Question: Are most scars gone after 1 year of abstinence?

Answer: yes


Question: Are herpes simplex virus and varicella-zoster virus gone after 1 year of abstinence?

Answer: no


Question: When are most scars gone Masson trichrome stain?

Answer: after abstinence


Question: When are most scars gone Masson trichrome stain?

Answer: after 1 year of abstinence


Question: What are dense and prominent?

Answer: portal infiltrates


Question: How are portal infiltrates in chronic hepatitis?

Answer: dense and prominent


Question: Are portal infiltrates dense and prominent?

Answer: yes


Question: Are normal media for comparison dense and prominent?

Answer: no


Question: What is there in acute hepatitis?

Answer: very little portal mononuclear infiltration


Question: Is there very little portal mononuclear infiltration in acute hepatitis or sometimes none at all?

Answer: yes


Question: Is the left atrium very little portal mononuclear infiltration in acute hepatitis or sometimes none at all?

Answer: no


Question: What shows characteristic portal tract expansion by a dense lymphoid infiltrate?

Answer: chronic viral hepatitis due to hcv


Question: What did chronic viral hepatitis due to HCV show?

Answer: characteristic portal tract expansion by a dense lymphoid infiltrate


Question: How did chronic viral hepatitis due to HCV show characteristic portal tract expansion?

Answer: by a dense lymphoid infiltrate


Question: Does chronic viral hepatitis due to HCV show characteristic portal tract expansion by a dense lymphoid infiltrate?

Answer: yes


Question: Does reversibly injured myocardium show characteristic portal tract expansion by a dense lymphoid infiltrate?

Answer: no


Question: What is associated with chronic alcohol use?

Answer: fatty liver disease


Question: What is fatty liver disease associated with?

Answer: chronic alcohol use


Question: How is fatty liver disease associated?

Answer: with chronic alcohol use


Question: Is fatty liver disease associated with chronic alcohol use?

Answer: yes


Question: Is the normal gland acini associated with chronic alcohol use?

Answer: no


Question: What is present in a characteristic perisinusoidal chicken wire fence pattern (Masson trichrome stain)?

Answer: some fibrosis


Question: What is some fibrosis present in?

Answer: the characteristic perisinusoidal chicken wire fence pattern


Question: Is some fibrosis present in a characteristic perisinusoidal chicken wire fence pattern (Masson trichrome stain)?

Answer: yes


Question: Is gross examination of a resected sigmoid colon present in a characteristic perisinusoidal chicken wire fence pattern (Masson trichrome stain)?

Answer: no


Question: What appears blue in this Prussian blue-stained section?

Answer: hepatocellular iron


Question: Where does hepatocellular iron appear blue?

Answer: in the prussian blue-stained section


Question: Does hepatocellular iron appear blue in this Prussian blue-stained section?

Answer: yes


Question: Does this abnormality appear blue in this Prussian blue-stained section?

Answer: no


Question: What is normal at this stage of disease,  even with such abundant iron?

Answer: the parenchymal architecture


Question: How is the parenchymal architecture of disease,  even with such abundant iron?

Answer: normal at this stage of disease