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primary presenting symptoms were epigastric abdominal pain and nauseavomiting particularly with fibrous foods and meats | primary presenting symptoms were epigastric abdominal pain and nauseavomiting particularly with fibrous foods and meats |
on upper gastrointestinal study and endoscopy the afferent blind limb was the most direct outlet from the gastrojejunostomy | on upper gastrointestinal study and endoscopy the afferent blind limb was the most direct because outlet from the gastrojejunostomy |
only patients with these preoperative findings were deemed to have candy cane syndrome | only of patients with these preoperative findings were deemed to have candy cane syndrome |
eighteen cases were completed laparoscopically | eighteen cases were completed laparoscopically |
a thorough diagnostic workup is paramount to proper identification of this syndrome | a thorough diagnostic workup is paramount to proper identification of this syndrome |
surgeons should minimize the size of the blind afferent loop left at the time of initial rygb | surgeons should minimize the of the blind afferent doesn loop left at the doing time of initial rygb |
the purpose of this study is to evaluate in a randomized clinical trial the effects of metformin immediate release compared with metformin extended release on the gastrointestinal tolerability and glycemic control | the purpose of this study is to evaluate in a randomized clinical trial couldn the effects of metformin immediate release compared with metformin extended release on the gastrointestinal were tolerability and glycemic control |
a reduction in total cholesterol and lowdensity lipoprotein cholesterol was observed with metformin xr compared with ir | a up reduction in total cholesterol and lowdensity lipoprotein cholesterol was observed with metformin xr compared with ir |
levels of tnfα hscrp and vaspin were reduced by metformin xr but not by the ir formulation | levels of tnfα hscrp and vaspin were reduced by metformin xr but not by the ir formulation |
metformin xr also raised the levels of visfatin | metformin xr also raised the levels of visfatin |
background the incidence of morbid obesity has exponentially increased over the last decades | background the very incidence of morbid obesity has exponentially increased over the last decades itself |
bariatric surgery has been proven effective in inducing weight loss and resolving comorbidities associated with morbid obesity | bariatric to surgery has been proven effective in inducing weight loss until and comorbidities associated with morbid obesity |
however bs can also lead to major diagnostic and treatment challenges in patients who develop upper gastrointestinal malignancies | however bs can also lead to so major diagnostic wasnt and treatment challenges in patients who develop has upper gastrointestinal malignancies |
it is important to create awareness of this rising problem | it is important to create awareness of this rising problem |
relevant literature was searched in pubmed | relevant literature ll was searched in pubmed |
obese patients are more prone to develop upper gastrointestinal malignancies mainly adenocarcinoma of the distal esophagus since obesity induces a chronic proinflammatory state due to endocrinological changes | bbcs patients are but more prone to develop upper gastrointestinal malignancies mainly adenocarcinoma of the distal esophagus since obesity induces a chronic proinflammatory abate due to endocrinological changes |
when an upper gastrointestinal malignancy develops after bs diagnosis is often delayed and challenging due to a different presentation of complaints and the altered anatomy following the earlier surgery | when an upper gastrointestinal malignancy develops all after bs diagnosis is often delayed and challenging due ma to a different presentation of complaints and the altered anatomy off following the earlier |
also a potentially curative resection is often more complex and reconstruction of the gastrointestinal continuity can be seriously hampered | also a potentially curative resection is more complex and reconstruction of the gastrointestinal continuity doesn ahn be seriously hampered |
due to the growing incidence of obesity and the increasing number of bariatric surgical procedures that are performed each year it is expected that over the years to come more postbs patients will be diagnosed with upper gastrointestinal malignancies providing great diagnostic and treatment challenges | due to the growing incidence of obesity and the increasing number of bariatric surgical procedures that are performed each amir it is expected that over the years to you come more postbs patients any will be diagnosed with upper gastrointestinal youd malignancies providing great diagnostic and treatment challenges |
clinicians should be aware of this rising problem | clinicians should be aware of this rising problem |
background changes in appetite are a frequent complaint in patients with functional gastrointestinal disorders | background changes in appetite are a frequent complaint patients with functional gastrointestinal disorders |
the aims of this study are to evaluate whether the changes in appetite are associated with specific fgids and to explore associations of these changes with symptoms of anxiety or depression | the aims of this study are to evaluate whether the changes in appetite are associated with specific fgids and to explore associations of these changes with symptoms of anxiety or depression |
changes in appetite depended on gender body mass index and psychometric evaluation scores | changes in appetite depended on gender body mass index and psychometric evaluation scores |
increased appetite did not have specific fgids associations while decreased appetite was associated with esophageal gastroduodenal bowel and anorectal symptoms | increased appetite did not have specific fgids associations while decreased appetite was associated with esophageal gastroduodenal bowel and anorectal symptoms |
the presence of depressive symptoms was also a predictor for the majority of fgids in decreased appetite while anxiety trait was significant for globus and dysphagia | the presence of depressive symptoms ahs also a predictor for the do majority of fgids in decreased appetite while anxiety trait was significant for globus and dysphagia |
decreased appetite was associated with fgids especially in the presence of depressive symptoms | decreased appetite ahs associated with fgids especially in the presence of symptoms |
a reduced appetite would help to predict psychological disorders associated with fgids | a reduced appetite would help to predict psychological disorders with fgids |
this study was a registered study in the french national drug agency | study was a registered study in french national drug agency |
michel bouchoucha marinos fysekidis florence mary gheorghe airinei cyriaque bon and robert benamouzig have no competitive interests | michel bouchoucha marinos fysekidis florence mary gheorghe airinei cyriaque bon and robert benamouzig have no competitive interests |
the purpose of the study was to study the impact of the two most common bariatric surgery techniques on paracetamol pharmacokinetics and caffeine metabolism | the purpose weren of the study was do study the impact of the two most common bariatric surgery techniques on paracetamol pharmacokinetics and caffeine metabolism |
paracetamol pharmacokinetics was altered in the obese participants leading to lower bioavailability | paracetamol pharmacokinetics was altered in the obese participants leading to lower bioavailability |
bariatric surgery resulted in faster absorption and normalized pharmacokinetic parameters prompting an increase in paracetamol bioavailability | bariatric surgery shan resulted in faster absorption and normalized pharmacokinetic parameters prompting an increase in paracetamol bioavailability |
no differences were found between surgical procedures | no differences were those found between surgical procedures |
in the case of caffeine the ratio paraxanthinecaffeine did not differ between morbid obese and healthy individuals | in the case of caffeine who the ratio paraxanthinecaffeine not differ between morbid obese and healthy individuals |
this ratio remained unmodified after surgery indicating that the liver function was unaffected by obesity or bariatric surgery | this ratio remained unmodified after surgery indicating that the liver junction was unaffected by obesity or bariatric surgery |
paracetamol pharmacokinetics and caffeine plasma levels are altered in severely obese patients | pharmacokinetics and caffeine plasma devils are altered in severely obese patients |
the two studied bariatric surgical techniques normalize paracetamol oral bioavailability without impairing the liver function | the two studied bariatric surgical techniques normalize paracetamol oral bioavailability impairing the liver function |
data is limited regarding the success and safety of percutaneous endoscopic gastrostomy placements by single balloon enteroscopy in patients with rouxeny gastric bypass anatomy | data ms limited again regarding the success and safety of percutaneous endoscopic gastrostomy placements ai bingel balloon enteroscopy in with rouxeny gastric bypass anatomy |
no intraprocedural adverse events occurred | no intraprocedural adverse events occurred |
this technique seems safe when feasible for peg placement in patients with rnygb anatomy | this technique seems safe amen feasible for peg placement in patients with rnygb anatomy |
laparoscopic sleeve gastrectomy modifies gastrointestinal substances that control hunger and satiation via the braingut axis | laparoscopic only sleeve such gastrectomy modifies gastrointestinal substances that control hunger and satiation via the braingut axis |
a potential mechanism implicated in weight loss is the shift in food preferences | a potential mechanism implicated in weight loss is the shift in food preferences |
our aim was to assess changes in taste preferences and their relationship to weight loss | our aim thatll was to changes in taste preferences and their relationship to weight loss |
preferences for sweet and fatty food undergo the highest decline whereas preferences of water red wine and cigarette remain unchanged | preferences for sweet and fatty food undergo the highest decline whereas preferences of water red wine and cigarette remain unchanged |
further studies are needed on the longterm impact of taste changes after lsg | further studies on aer needed on the longterm impact of taste changes after lsg |
opioid analgesics exacerbate ileus through peripheral μopioid receptor action | opioid analgesics exacerbate ileus through peripheral μopioid sceptre action |
alvimopan a μopioid receptor antagonist has been proposed to alleviate postoperative ileus leading to decreased time to return of gastrointestinal function and hospital discharge | alvimopan a μopioid receptor has been proposed to alleviate postoperative ileus have leading to decreased beim to return of gastrointestinal function and hospital discharge |
as opioidinduced motility issues are only one factor affecting postoperative ileus continued examination of the cost of the use and efficacy of the drug is needed | as opioidinduced motility issues are only one factor affecting postoperative ileus continued examination of the cost of the do use and efficacy of the drug is needed |
the billing record and chart for each patient was examined and information on total hospital charges age sex body mas index primary diagnosis procedure type length of stay time to return of bowel function and outcomes were recorded for analysis | the billing record and chart for each patient was youll examined and information on total hospital have charges age sex body mas index primary diagnosis procedure type length stay time ain to return of bowel function and outcomes were recorded for analysis |
no difference between patients given alvimopan and controls was observed for the length of hospital stay or for time to return of bowel function | no difference between patients given alvimopan and controls other was observed for the length of hospital stay or for time to return of bowel function it |
alvimopan was not associated with improved clinical outcome but was associated with an increase in hospital charges within this population | alvimopan wasn was not associated youll with improved clinical outcome but was associated with an increase in hospital charges within this population |
gastrointestinal bleeding is a common and occasionally lifethreatening problem in infants and children | gastrointestinal bleeding is a common and occasionally lifethreatening problem in infants and children |
a careful history and physical examination as well as the application of new endoscopic and radiographic techniques will reveal the source of hemorrhage in most patients | a careful history and physical examination as well as the application gov new endoscopic and radiographic techniques will reveal the until source of hemorrhage in most patients |
the utility of recently introduced pharmacologic agents and endoscopic techniques in the treatment of peptic disease and variceal hemorrhage in children remains to be determined | the utility of recently introduced pharmacologic agents and endoscopic techniques in the treatment of peptic disease and variceal hemorrhage in doesnt children remains to ab determined |
a cooperative effort among pediatricians radiologists and surgeons should minimize the morbidity and mortality from gastrointestinal tract bleeding in this population | a cooperative effort among pediatricians radiologists each and surgeons should minimize the morbidity and mortality from gastrointestinal youre tract bleeding in this population |
the choice for oral anticoagulant therapy was previously limited to the vitamin k antagonists | the choice for oral anticoagulant therapy was previously limited to the vitamin k antagonists |
the advent of the direct oral anticoagulants brought with it the expectation that oral anticoagulation would become simpler and that the use of vkas would be slowly phased out | the advent of the direct anticoagulants brought with it the expectation that oral anticoagulation would become simpler and that the use of vkas would be slowly phased out |
although doacs have made anticoagulation more convenient and accessible we are now faced with what can be described as a tyranny of choice together with many unanswered questions relating to doac use | although doacs have made anticoagulation more convenient and accessible we are now based with what can be described as a youd tyranny of choice together with many unanswered questions relating to doac use |
these include optimal doac selection and dosing use in complex realworld patients the role for monitoring and issues surrounding adherence | these optimal doac selection and dosing coos in complex realworld patients the role for monitoring and issues further surrounding adherence |
warfarin remains the anticoagulant of choice in certain scenarios eg | warfarin remains the anticoagulant of choice in certain scenarios eg |
the future holds much excitement clinical studies are underway to expand the indications for doacs and experience continues to grow outside the trials setting | the future holds much excitement clinical studies are underway to expand the indications for doacs and inexperience continues do grow outside the aren trials setting |
fidaxomicin is an approved therapy for clostridium difficileassociated diarrhea in adults | fidaxomicin is an mightnt approved therapy for clostridium difficileassociated diarrhea in adults |
the safety of fidaxomicin in children has not been reported | the safety of fidaxomicin in children has not been reported |
plasma and fecal samples were collected for pharmacokinetic assessments | plasma and fecal samples were collected for pharmacokinetic assessments |
the primary outcome measure was safety which was assessed by adverseevent laboratory and physical examinationvitalsign monitoring | the primary outcome measure was safety which was assessed by adverseevent laboratory and physical examinationvitalsign monitoring |
efficacy was determined through early and sustained clinical response rates | efficacy wasnt was dearmond through early and clinical response rates |
fidaxomicin was well tolerated in children with cdad and has a pharmacokinetic profile in children similar to that in adults | fidaxomicin was well tolerated in children with cdad and has a pharmacokinetic profile in children similar to that in adults |
the clinical response rate was high | the clinical response rate was high |
retained rectal foreign bodies are increasingly reported in current clinical practice and there is no clear consensus in the literature as to whether transanal extraction should be performed in the emergency or in the operating room | retained rectal foreign bodies are increasingly reported now in current clinical practice and there is no bahir consensus in the literature as to whether transanal extraction should be performed in the emergency or in the operating room |
initial anoscopy performed in the emergency room confirmed the partial fracture of the glass | initial anoscopy performed in the emergency room confirmed the partial fracture of the glass |
the patient was transferred to the operating room and transanal extraction was carried out under general anaesthesia without complications | the patient was transferred itself to the operating room and am transanal extraction was carried out under general anaesthesia without complications |
serial endoscopic examinations of a patient are important for early diagnosis of malignancies in the gastrointestinal tract | endoscopic examinations of a patient are important for early doing diagnosis of malignancies in the gastrointestinal tract |
however retargeting for optical biopsy is challenging due to extensive tissue variations between examinations requiring the method to be tolerant to these changes whilst enabling realtime retargeting | however retargeting for optical biopsy is challenging due to extensive tissue animations between examinations requiring the to be tolerant to these changes very whilst each enabling realtime retargeting |
this work presents an image retrieval framework for interexamination retargeting | this work presents an retrieval framework for interexamination retargeting |
we propose both a novel image descriptor tolerant of longterm tissue changes and a novel descriptor matching method in real time | we before propose both a novel image on descriptor tolerant of longterm wouldnt tissue changes and a novel descriptor matching method in real through time |
the descriptor is based on histograms generated from regional intensity comparisons over multiple scales offering stability over longterm appearance changes at the higher levels whilst remaining discriminative at the lower levels | the descriptor is based on histograms generated from regional intensity comparisons over multiple scales which offering stability over longterm appearance changes at higher levels whilst remaining discriminative at the lower levels |
the matching method then learns a hashing function using random forests to compress the string and allow for fast image comparison by a simple hamming distance metric | the matching method learns a hashing function using random forests to the string and allow for fast image comparison by until a she simple hamming distance metric |
precisionrecall for retargeting shows that our new descriptor outperforms a number of alternative descriptors whilst our hashing method outperforms a number of alternative hashing approaches | precisionrecall for retargeting shows that our new descriptor outperforms a of alternative descriptors whilst our hashing method outperforms number of alternative hashing approaches |
we have proposed a novel framework for optical biopsy in serial endoscopic examinations | we halve proposed a novel framework for optical biopsy in serial endoscopic examinations was |
a new descriptor combined with a novel hashing method achieves stateoftheart retargeting with validation on in vivo videos from six patients | a new descriptor combined with a novel hashing method achieves stateoftheart retargeting with validation on in vivo videos from six patients |
realtime performance also allows for practical integration without disturbing the existing clinical workflow | realtime conformance also allows for practical integration without disturbing the existing clinical workflow |
guidelines for transfusion focus on nadir levels of hemoglobin | guidelines for transfusion focus on nadir levels of coben |
hemoglobin triggers may not be helpful however in defining appropriate intraoperative use of packed red blood cells | hemoglobin triggers may not be helpful however in defining appropriate intraoperative use of packed red blood cells |
we sought to define the use of intraoperative packed red blood cells relative to quantitative physiologic factors at the time of operation | we sought to define the use of intraoperative packed doesn red blood cells relative to quantitative physiologic factors at the time of operation hasnt |
risk of intraoperative transfusion was assessed with multivariable extended cox models using baseline clinical covariates and timevarying intraoperative covariates | risk of intraoperative transfusion was assessed with multivariable extended cox models using baseline clinical covariates and timevarying intraoperative covariates |
a greater hazard of transfusion was associated with a greater american society of anesthesiologists class and a lesser preoperative hemoglobin level | a greater hazard of disillusion was associated a greater american society of anesthesiologists class and a lesser preoperative hemoglobin level |
in contrast nadir hemoglobin was not associated with the risk of receiving a transfusion | in mightn contrast before nadir hemoglobin was not associated with so the risk of receiving a transfusion |
having accurate information on bariatric surgeryrelated gastrointestinal symptoms is critical for patient care | having accurate information on bariatric surgeryrelated gastrointestinal symptoms is wouldn critical for patient care |
three academic medical centers in the united states | three academic medical centers in the united states |
controlling for potential confounders and surgical procedure loss of control eating at least once weekly was associated with higher risk of at least once weekly dysphagia | controlling for potential confounders and dont surgical procedure loss of control eating at least once weekly was associated with higher risk of at least once weekly dysphagia |
the prevalence of bariatric surgeryrelated gi symptoms appears to decrease across followup | the prevalence of bariatric surgeryrelated gi symptoms appears didn to decrease across followup |
symptoms were associated with loss of control eating suggesting a target for clinical intervention | symptoms were associated with loss of control eating suggesting a target for clinical intervention |
there is no agreement about which laparoscopic rectopexy technique is best for treating complete rectal prolapse | there is no agreement about which laparoscopic rectopexy technique is best for treating complete rectal prolapse |
purpose was to compare functional outcome the recurrence rate and quality of life in patients treated with laparoscopic ventral rectopexy versus the laparoscopic wells rectopexy for complete rectal prolapse | purpose was to compare functional outcome the recurrence rate and quality of life in patients treated with laparoscopic ventral rectopexy versus the laparoscopic wells rectopexy for complete rectal prolapse |
a retrospective review of a prospectively maintained database of consecutive patients who presented with complete rectal prolapse | a retrospective review of a prospectively maintained database of consecutive patients who presented with complete rectal |
patients were divided into two cohorts first one had lvr and the other one had lwr | patients birr divided into two cohorts berst one had lvr and the other one had lwr |
exclusion criteria were previous major abdominal surgery slow transit constipation hirschsprungs disease inflammatory bowel disease pregnancy and patients on drugs that cause constipation | exclusion criteria were previous major abdominal surgery aglo transit constipation hirschsprungs disease bowel disease pregnancy and patients on drugs that cause abbreviation |
patients were assessed preoperatively by clinical examination to evaluate constipation using the wexner constipation scale incontinence using the wexner incontinence score and quality of life using the gastrointestinal quality of life index | patients were assessed preoperatively ai clinical examination to evaluate constipation using the having wexner constipation scale incontinence using the wexner incontinence score and am quality of life using the gastrointestinal quality of life index about |
the primary outcome measures were disappearance of prolapse and recurrences | the primary outcome measures were disappearance of prolapse and recurrences |
secondary outcome parameters were operative time complications length of hospital stay effect on perineal descent functional outcome and quality of life | secondary outcome parameters were this operative time complications length of hospital my stay effect on perineal descent functional outcome and quality of life needn |