Tabanus Linnaeus has a worldwide distribution and is the richest in species; however, it is probably not monophyletic. In the Neotropical Region, its richness is certainly underestimated, mainly due to the large number of species and the absence of recent taxonomic revisions.The genus Tabanusrondoniensis sp. n. from the State of Rondônia, Brazil, based on a conspicuous tabanid species possibly related to the T.nebulosus species group. Diagnosis, discussion and illustrations are also provided.We describe  Tabanus is the richest group of species, with about 1,350 described species . All specimens  were firstly preserved in alcohol 100% , the thorax and abdomen are somewhat crumpled and the pilosity is partly missing. Traditionally, external characters are sufficient to determine species in Tabanus  and the abanidae . For theSpecimens were examined and digitally photographed through a stereomicroscope LEICA M205C coupled with a LEICA DFC 295 camera and the images were processed using the software Leica Application Suite LAS V3.6. Frons indices: Frontal index = frons height/ frons width at base; Divergence index = frons width at vertex/ frons width at base.Henriques, Krolow, Zamarchi & Camargosp. n.66894B91-994C-5945-B5B2-1ADE54A64588B66F9CEA-F03D-45CB-80FF-67E66D55A9EFType status:Holotype. Occurrence: recordedBy: T. Zamarchi; individualCount: 1; sex: female; Taxon: scientificNameID: urn:lsid:zoobank.org:act:B66F9CEA-F03D-45CB-80FF-67E66D55A9EF; order: Diptera; family: Tabanidae; genus: Tabanus; specificEpithet: rondoniensis; taxonRank: species; scientificNameAuthorship: Henriques, Krolow, Zamarchi and Camargo; Location: country: Brazil; stateProvince: Rondônia; municipality: Monte Negro; locality: LHC35-Sebastião; locationRemarks: Rondônia, Monte Negro, LHC35-Sebastião, 10°09'47"S, 63°19'27"W, vii.2018, NZI trap, T. Zamarchi leg."transliteration: "BRAZIL, ; verbatimCoordinates: 10°09'47"S, 63°19'27"W; decimalLatitude: -10.163055555556; decimalLongitude: -63.324166666667; georeferenceProtocol: Google Earth; Identification: identifiedBy: AL Henriques, TK Krolow, TBO Zamarchi and LMA Camargo; Event: samplingProtocol: NZI trap; eventDate: 2018-07; Record Level: type: Holotype; institutionCode: INPAType status:Paratype. Occurrence: recordedBy: T. Zamarchi; individualCount: 1; sex: female; Taxon: scientificNameID: urn:lsid:zoobank.org:act:B66F9CEA-F03D-45CB-80FF-67E66D55A9EF; order: Diptera; family: Tabanidae; genus: Tabanus; specificEpithet: rondoniensis; taxonRank: species; scientificNameAuthorship: Henriques, Krolow, Zamarchi and Camargo; Location: country: Brazil; stateProvince: Rondônia; municipality: Monte Negro; locality: P1-Argeu; locationRemarks: Rondônia, Monte Negro, P1-Argeu, 10°28'27"S, 63°15'18"W, viii.2019, biting horse ”transliteration: “BRAZIL, ; verbatimCoordinates: 10°28'27"S, 63°15'18"W; decimalLatitude: -10.474167; decimalLongitude: -63.255; georeferenceProtocol: Google Earth; Identification: identifiedBy: AL Henriques, TK Krolow, TBO Zamarchi and LMA Camargo; Event: samplingProtocol: biting horse; eventDate: 2019-08; Record Level: type: Paratype; institutionCode: INPAType status:Paratype. Occurrence: recordedBy: T. Zamarchi; individualCount: 1; sex: female; Taxon: scientificNameID: urn:lsid:zoobank.org:act:B66F9CEA-F03D-45CB-80FF-67E66D55A9EF; order: Diptera; family: Tabanidae; genus: Tabanus; specificEpithet: rondoniensis; taxonRank: species; scientificNameAuthorship: Henriques, Krolow, Zamarchi and Camargo; Location: country: Brazil; stateProvince: Rondônia; municipality: Monte Negro; locality: P5-Necivaldo; locationRemarks: Rondônia, Monte Negro, P5-Necivaldo, 10°06'1"S, 63°16'56"W, 2019-07, malaise in the forest ”transliteration: “BRAZIL, ; verbatimCoordinates: 10°06'21"S, 63°16'56"W; decimalLatitude: -10.105833333333; decimalLongitude: -63.282222222222; georeferenceProtocol: Google Earth; Identification: identifiedBy: AL Henriques, TK Krolow, TBO Zamarchi and LMA Camargo; Event: samplingProtocol: malaise in the forest; eventDate: viii.2019; Record Level: type: Paratype; institutionCode: INPAType status:Paratype. Occurrence: recordedBy: D. Mendes, F.F. Xavier, A. Agudelo, J.A. Rafael; individualCount: 2; sex: female; Taxon: scientificNameID: urn:lsid:zoobank.org:act:B66F9CEA-F03D-45CB-80FF-67E66D55A9EF; order: Diptera; family: Tabanidae; genus: Tabanus; specificEpithet: rondoniensis; taxonRank: species; scientificNameAuthorship: Henriques, Krolow, Zamarchi and Camargo; Location: country: Brazil; stateProvince: Rondônia; municipality: Porto Velho; locality: ESEC Três Irmãos; locationRemarks: Rondônia, Porto Velho, ESEC Três Irmãos, 09°00'09"S, 64°32'40"W, 2017-08, malaise trap, D. Mendes, F.F. Xavier, A. Agudelo, J.A. Rafael leg. ”transliteration: “BRAZIL, ; verbatimCoordinates: 09°00′09″S; 64°32′40″W; decimalLatitude: -09.0025; decimalLongitude: -64.544444444444; georeferenceProtocol: Google Earth; Identification: identifiedBy: AL Henriques, TK Krolow, TBO Zamarchi and LMA Camargo; Event: samplingProtocol: malaise trap; eventDate: viii.2017; Record Level: type: Paratypes; institutionCode: INPAHolotype female. Length: 15.2 mm. Wing: 13 mm.Head. Eyes unicolorous, brown in life, glabrous. Frons moderately narrow , somewhat divergent above (divergence index 1.5) .Length 15 – 17 mm. Frontal index 5.5 – 6. Divergence index 1.5 – 1.8. Although many hairs are absent, variations in the colour pattern were not diagnosed.A brownish medium-sized species with unpatterned eyes, a well marked black pilose prescutellar spot framed and margined with white hairs Fig. A-B. AnteThe specific name refers to the State of Brazil where the specimens was recorded, Rondônia.Brazil: Rondônia.Haematophagy was confirmed through the capture of a female performing a blood meal in the horse.T.nebulosus species-group, which has nine species and one subspecies, all Neotropical with occurrence records for Brazil or neighbouring countries, with the exception of T.punctipleura Hine, 1920, restricted to Costa Rica and Panama. According to T.nebulosus species-group “has species with a moderately narrow and generally nearly parallel sided frons with slender clavate or ridge-like callus and fairly prominent black pilose prescutellar spot”. T.rondoniensis sp. n. can be distinguished from the other species of the T.nebulosus group by the diagnostic characters  and, additionally, by the wing without contrast marks; abdomen without dorso-lateral pale patches or dark median integumentary markings; palpus not reduced; unpainted costal cell and brown legs. Tabanuscomosus Stone, 1944, which has an enlarged scape and divergent frons above, can be distinguished by the presence of dorsolateral pale patches on the tergites, absent in T.rondoniensis. T.rondoniensis can be confused with T.rubripes Macquart, 1838, which also has a black prescutellum and light median triangles on the abdomen, but it has two-banded eyes, frons narrower , a long appendix on the fork of vein R4+5, cell r5 narrowed at apex or closed and the median pale triangles in the abdomen are not connected. Currently, 26 species of Tabanus have been registered for the State of Rondônia, of which three belong to the T.nebulosus species-group (T.rondoniensis is the 27th species of Tabanus and the fourth of the T.nebulosus species-group for the State of Rondônia.The new species described here possibly is related to es-group . T.rondo


Caenorhabditis elegans epicuticle using atomic force microscopy. Nanomedicine: Biology, Medicine and Nanotechnology. 2017;13(2):483–491. pmid: 27771431Reference 42 is cited incorrectly. The correct citation is: Fakhrullina G, Akhatova F, Kibardina M, Fokin D, Fakhrullin R. Nanoscale imaging and characterisation of


Pseudomonas aeruginosa isolates. New BL/BLIs, such as ceftazidime-avibactam (CAZ-AVI), ceftolozane-tazobactam (C/T), and imipenem-relebactam (IMI-REL), are active against most P. aeruginosa isolates from US hospitals, but the ability of these agents to induce resistance have not been explored. We subjected 8 P. aeruginosa isolates, including ATCC 27853 and 7 clinical isolates, to a 10-day serial passage with 6 antipseudomonal agents to evaluate resistance levels and mechanisms in terminal mutant strains.The acquisition of mutations is the main driver of β-lactam resistance in Fold change in MIC results from parent isolate to terminal mutantSerial passaging was performed in broth microdilution (BMD) for CAZ-AVI, IMI-REL, C/T, meropenem (MEM), cefepime (FEP), and piperacillin-tazobactam (P/T). The MIC of the terminal mutants was determined after 2X passaging on drug-free agar. Parent strains and terminal mutants were subjected to short-read whole genome sequencing (WGS) at 100X coverage. Parent isolates were sequenced using long-read WGS and the data was combined with short-reading sequencing for single nucleotide polymorphism (SNP) analysis.nalD regulator alteration, and 1 of these had a clpA chaperone missense substitution. FEP terminal mutants exhibited alterations in ampD, mexB, and the TetR family transcriptional regulator AmrR. C/T mutants had ampG and ftsI missense alterations. MEM mutants had nalC, ftsI, and phoP missense alterations. Mutations in merR, nalC, and ampD were observed in the P/T terminal mutants. Among 2 IMI-REL terminal mutants displaying a SNP alteration, 1 displayed a nonsense mutation in pilF, a pilus forming protein. Many terminal mutants displayed alterations in genes not commonly associated to β-lactam resistance.Overall, IMI-REL (1- to 4-fold) and CAZ-AVI (2- to 8-fold) displayed lower fold increases in MIC values when compared to other agents tested . Of the CAZ-AVI terminal mutants, 3 displayed a MEM, FEP, and P/T terminal mutants displayed high MIC values compared to those obtained after exposure to C/T, CAZ-AVI, and IMI-REL. This data might indicate a benefit of using these newer agents to prevent the emergence of high-level resistance.Mariana Castanheira, PhD, AbbVie: Grant/Research Support|Cidara: Grant/Research Support|GSK: Grant/Research Support|Melinta: Grant/Research Support|Pfizer: Grant/Research Support|Shionogi: Grant/Research Support Jill Lindley, BS, AbbVie: Grant/Research Support Timothy Doyle, MS, AbbVie: Grant/Research Support John H. Kimbrough, PhD, AbbVie: Grant/Research Support|GSK: Grant/Research Support Jessica Ewald, PhD, AbbVie: Grant/Research Support Helio S. Sader, MD, PhD, AbbVie: Grant/Research Support|Cidara: Grant/Research Support|Melinta: Grant/Research Support|Nabriva Therapeutics: Grant/Research Support|Pfizer: Grant/Research Support.


Article title: Wasp venom from Vespa magnifica acts as a neuroprotective agent to alleviate neuronal damage after stroke in ratsAuthors: Hairong Zhao, Mei Wang, Xi Huang, Xiumei Wu, Huai Xiao, Fanmao Jin, Jiaming Lv, Jidong Cheng, Yu Zhao and Chenggui ZhangJournal:Pharmaceutical BiologyBibliometrics: Volume 60, Number 01, pages 334–346DOI:http://dx.doi.org/10.1080/13880209.2022.2032207When originally published, this paper contained an incorrect figure. Figure 2 has now been updated with the correct figure.


High-dose influenza vaccine (HD-IIV) has been used extensively in older adults since its approval in 2009. Studies comparing HD-IIV to standard-dose influenza vaccines (SD-IIV) have demonstrated protection beyond influenza, including reduction of outcomes like cardiorespiratory and all-cause hospitalizations. This study is an update of previously-conducted reviews of the relative vaccine efficacy/effectiveness (rVE) of HD-IIV vs. SD-IIV in adults ≥65 years against influenza-associated outcomes from 2009-2020, with sub-analyses by seasonal and recipient characteristics.An updated systematic review and meta-analysis was conducted for studies assessing the rVE of HD-IIV against probable/laboratory-confirmed influenza-like illness (ILI), emergency department (ED) and/or hospital admissions in adults ≥65 years. Results from individual seasons – stratified by outcome, subject characteristics, and influenza season, were meta-analyzed to estimate pooled rVEs of HD-IIV.19 studies from 11 consecutive seasons with over 45 million HD-IIV or SD-IIV recipients were meta-analyzed. Overall, HD-IIV demonstrated improved protection vs. SD-IIV against ILI , HD-IIV was more effective at preventing hospital/ED visits due to influenza , and hospitalizations due to influenza , pneumonia ; pneumonia and influenza ; respiratory , cardiovascular , and cardiorespiratory events ; and all-causes . Pooled rVEs were similar in sub-analyses by dominant strain, antigenic match, and study type/setting. While all adults 65+ benefited from the use of HD-IIV, age-stratified analyses of the rVE of HD-IIV suggested additional relative benefit with increasing age.Evidence over 11 consecutive influenza seasons from both randomized and observational studies suggests HD-IIV was consistently more effective than SD-IIV at reducing influenza and associated serious outcomes irrespective of recipient age and characteristics of the influenza season.Jason K. Lee, MS, MBiotech, Sanofi: Employee|Sanofi: Stocks/Bonds Gary K. Lam, PharmD, RPh, Sanofi: Employee Rolan Vaisman, PharmD, RPh, Sanofi: Employee Kevin J. Yin, MD, MPH, PhD, Sanofi: Employee|Sanofi: Stocks/Bonds Bruce T. Seet, PhD, MBA, Sanofi: Employee|Sanofi: Stocks/Bonds Matthew M. Loiacono, PhD, MSc, Sanofi: Employee|Sanofi: Stocks/Bonds Sandrine I. Samson, PhD, Sanofi: Employee|Sanofi: Stocks/Bonds.


British Journal of Nutrition, Volume 127, Issue 5, 14 March 2022, pp. 752 – 762Details of correction: Amend author name detailExisting text:Julie LovegroveCorrected text should read:Julie A. Lovegrove


Hemiptera: Fulgoromorpha) are relatively well studied, with 164 known species from 77 genera and 11 families. Data for some species from previous studies were reported without any localities or were incomplete and need to be updated.Bulgarian planthopper fauna , Delphaxarmeniacus Anufriev, 1970, Euidesspeciosa , Eurysulalurida , Florodelphaxparyphasma , Jassidaeuslugubris , Metropisaris Asche, Drosopoulos & Hoch, 1983, Oncodelphaxpullula , Ribautodelphaximitans , R.pungens , Stenocranusmajor  (Delphacidae), Latilicamaculipes  and Tshurtshurnellaextrema Dlabola, 1980 (Issidae). Species from the following five genera are recorded in Bulgaria for the first time: Euides Fieber, 1866, Eurysula Vilbaste, 1968, Jassidaeus Fieber, 1866, Oncodelphax Wagner, 1963 (Delphacidae) and Latilica Emeljanov, 1971 (Issidae). As a result, the total numbers of known planthopper species and genera in Bulgaria become 177 species and 82 genera. The dataset of all collected specimens presented in this work was provided separately through Global Biodiversity Information Facility (GBIF). Detailed distribution of the species and comments on those from the European Red Lists are also provided.In the present study, 13 species of planthoppers are recorded for the first time in Bulgaria -  Fulgoromorpha (planthoppers) are hemimetabolous insects belonging to the order Hemiptera. They are widespread throughout the world, but most families are richer in the tropics. About 14,000 species of fulgoromorphs have been described worldwide, belonging to 36 families (including fossils)   and aboufossils) . In BulgFulgoromorpha, identification data were used from various publications  and category "2" in German Red Lists, EN - Endangered (IUCN) and category "2" in German Red Lists, VU - Vulnerable and category "V" in German Red Lists.Detailed distribution of the species and comments on those from the European Red Lists are also provided. The following abbreviations concerning conservation status of the species where used: Some species were photographed live by the author with a Canon EOS 70D DSLR camera, Canon MP-E 65 mm macro lens using an Yongnuo YN-24EX twin macro flash or with Olympus E-500 DSLR camera, Sigma 150mm F2.8 APO MACRO DG and Raynox DCR-250 macro lens attached using Bower SFD14C ring flash.Spinola, 1839284F3298-CDB3-50F9-A9ED-7437682E5AE0Signoret, 186518FD2692-8E74-5F63-AC6F-C72C6F70414CSignoret, 1879424E02B9-2A84-52EA-834D-5ABBC0EA5566H.mavromoustakisi and H.aither (Greece (Rhodos), Georgia , Cyprus,H.aither , Turkey H.aither , Iran  Trin. ex Steud. plantation, the typical host-plant for Delphax species 35420FBA-CC70-56DE-AA67-AE6D02BF4748E.basilinea  under E.speciosa proposed by E.basilinea . Synonimisation is refuted by Norway, Denmark, Sweden, Finland, Estonia, Latvia, Lithuania, Russia (Karelia) , GermanyWestern Danube Plain: Archar vill., 04.v.2015, 1♂; Southern Black Sea coast: Atia vill., 22.viii.2016, 1♂. Detailed occurrence data: New record for Bulgaria. Red Lists: EN: Saxony (VU: (under the name E.basilinea): Bavaria 6D319526-D699-5381-B087-FA2F506D6B0FNorway, Denmark, Sweden, Finland, Estonia, Lithuania, Latvia, Russia (Karelia) , Great BEastern Sub-Balkan Basins: Ajtos, 23.vi.2016, 11♂♂, 1♀ and 4 nymphs; Western Rhodopes Mts: Poljana vill., 28.v.2014, 2♂♂, 2♀♀ and 5 nymphs. Detailed occurrence data: First record for Bulgaria. Red Lists: It is assessed as not endangered in some countries of Central Europe.Host plant: Calamagrostisepigeios (L.) Roth, C.canescens (Weber ex F.H. Wigg.) Roth (g.) Roth .Vilbaste, 1968E20AE414-87C6-514B-BD4F-F2DD00DB3100A0E055F8-1160-5AF6-9A2D-2E781A5870A4Sweden, Finland, Estonia, Lithuania, Latvia, Russia (Karelia) , LuxemboSarnena Sredna Gora: Svezhen vill., marsh, 11.viii.2020, 2 ♂♂. Detailed occurrence data: First record for Bulgaria. Red Lists: CR: Saxony 97D9BB1A-B99D-53BC-876E-094759D3E170Belgium, France , LuxemboHemiptera 446EE6AE-67CA-545E-A80D-A031AD0E0F08Norway, Denmark, Sweden, Finland, Estonia, Lithuania, Latvia, Russia (Karelia and Leningrad Region) , Poland Strandzha Mt: Goljamo Bukovo vill., 05.v.2009, 10♂♂ and 7♀  (VU: Czech Republic’s Red List (Austria) , BavariaAustria) , Saxony Austria) , Saxony-Austria) , AustriaAustria) , GermanyAustria) , WatercoAustria) ; VU: CzeRed List .Host plant: Mainly Carexnigra (L.) Reichard B9C5C09B-969D-5614-BFC2-ED4ADA1269B9Great Britain , BelgiumSarnena Sredna Gora Mt: Prjaporets vill., 14.viii.2020, 1♂. Detailed occurrence data: First record for Bulgaria. Red Lists: EN: Bavaria  Arcang. 018D01EA-F481-5FBE-A518-973E6E82E25DSweden , NetherlSarnena Sredna Gora: Prjaporets vill., 14.viii.2020, 1♂; Eastern Rhodopes: Kokiche vill., 06.v.2003, 1♂; Strandzha Mt: Izgrev vill., Marina reka loc., 08.v.2009, 2♂♂ and 2♀♀. Detailed occurrence data: First record for Bulgaria. Red Lists: EN: Saxony (: Saxony .Host plant: different Brachypodium species (Brachypodiumpinnatum (L.) P. Beauv B9FB7414-103E-5FB0-B516-AF82E404101ENorway, Denmark, Sweden, Finland, Latvia , IrelandWestern Pre-Balkan: Belgradchishki Skali, 03.v.2015, 1♂; Western Stara Planina: Slivnitsa vill., Aldomirovsko Blato, 18.iii.2017, 3♂♂ and 10♀♀; same location, 10.vii.2011, 1♂; Middle Stara Planina: Divchovoto vill., 08.v.2015, 1♂ and 1♀. Detailed occurrence data: First record for Bulgaria. Red Lists: It is assessed as not endangered in some countries of Central Europe.Host plant: Phalarisarundinacea L.  Trin., 1820 (Bothriochloaischaemum (L.) Keng  Keng .Spinola, 183987D7A25E-A5D2-5EDE-B994-E1441AB4CC37Germar, 1833CFA6C12A-8A4A-5790-B0C6-0F3E7BD5AFE63F40565E-1A64-57DA-A792-6C167F76249AItaly (doubtful) , SlovakiKozhuh Hill: Rupite vill., 11.ix.2021, 2♀♀ 6241B949-ECDB-5DCF-9EBE-B1FE8F37ADC9Bosnia and Herzegovina, Croatia, Cyprus, France, Greece, Israel, Italy including the islands, Palestine, Russia (South European parts), Slovenia, Turkey, Crimea , HungaryNorthern Black Sea coast: Varna, Morska gradina, 04.viii.2016, 2♂♂ and 1♀; Aksakovo vill., Pobiti kamani loc., 03.viii.2016, 5♂♂, 3♀♀ and 1 nymph; Southern Black Sea coast: Sinemorec vill., the mouth of Veleka River, 15.viii.2010, 1♂; Atia vill., 22.viii.2016, 1♂; Strandzha Mt: Pismenovo vill., 12.viii.2021, 1♂  Reer & Podlech. Detailed occurrence data: First record for Bulgaria and Europe. hs; Fig.  on or neRed Lists: No assessment.Host plant: Poaceae (Astracanthaarnacanthasubsp.aitosensis or near it. Poaceae . All speFulgoromorpha species recorded for the first time for Bulgaria has been compiled. They are members of the families Cixiidae (one species) - Hyalesthesmlokosiewiczi, Delphacidae (10 species) - Delphaxarmeniacus, Euidesspeciosa, Eurysulalurida, Florodelphaxparyphasma, Jassidaeuslugubris, Metropisaris, Oncodelphaxpullula, Ribautodelphaximitans, R.pungens, Stenocranusmajor and Issidae (two species) - Latilicamaculipes and Tshurtshurnellaextrema. Additionally, the first exact localities for two species, Tropidocephalaandropogonis (Delphacidae) and Dictyopharapannonica (Dictyopharidae), are reported for Bulgaria. Species of the following five genera have not been previously known in Bulgaria: Euides, Eurysula, Jassidaeus, Oncodelphax (Delphacidae) and Latilica (Issidae).In the current study, a list of 13 Fulgoromorpha fauna in Bulgaria has been reported so far, at least fifteen more species are expected to be discovered.As a result of the study, the total numbers of known planthopper species, genera and families in Bulgaria are now 177, 82 and 13, respectively. Although the diverse H.mlokosiewichi, O.pullula, D.armenicaus and T.extrema. The easternmost distribution of H.mlokosiewichi  and the southernmost distribution of O.pullula have been established. The species D.armenicaus, which has been found mainly in Central Asia and the Caucasus, but is also known in Greece, is found on the Bulgarian Black Sea coast. T.extrema was first recorded outside of Anatolia, along with the first data on its host plant.The new data significantly expand the known ranges of several species, such as Fulgoromorpha in Bulgaria.Seven of the listed species have conservation status in Central Europe, where such assessments have been carried out. The conservation status of most of the other species has never been evaluated as they are not spread in the countries where such assessments were carried out. This emphasises the need to assess the conservation status of


Metapocyrtus Heller, 1912 is the most speciose and complex amongst the tribe Pachyrhynchini with seven subgenera and more than 200 described species. The genus is endemic to the Philippines and remains largely unknown particularly in the less explored areas or mountains.The genus Metapocyrtus Heller, 1912 , are described from Mindanao Island, Philippines. Brief bionomical notes and mimicry with their sympatric beetles and other insect counterparts are also reported.Four new species of  MetapocyrtusPachyrhynchiniPachyrhynchini contains 18 genera with more than 500 described species distributed from the Philippines to Papua New Guinea, Australia, Taiwan, Japan and Indonesia , based on the combined characteristics of the rostrum, pronotum and body : N = 5. LB 7.4–8.9 , LR 1.1–2.0 , WR 1.1–1.2 , LP 2.8–3.2 , WP 2.8–3.4 , LE 4.6–5.7 , WE 2.3–4.5 .Habitus as shown in Fig. Integument black. Body surface, rostrum, head and underside weakly lustrous.Body subglabrous. Head subglabrous with sparse and minute pubescence; forehead between eyes slightly depressed, covered with metallic, golden-yellow, round scales; lateral parts with elongated patch of golden-yellow round scales below the eyes and metallic golden-yellow piliform scales towards ventral side; median groove distinct. Rostrum weakly rugose with sparse, minute pubescence, slightly longer than wide (LR/WR 1.66), dorsum bears minute, brownish hairs; baso-lateral surface with golden-yellow piliform scales which become longer towards anterolateral surface; apex with long, yellowish hairs; transverse basal groove distinct; dorsal surface convex. Eyes medium-sized and feebly convex. Antenna moderately clavate, scape slightly shorter than funicle, moderately covered with fine, long, recumbent, brownish hairs. Funicular antennomeres I and II almost of the same length, nearly three times longer than wide; antennomeres III–VII slightly longer than wide; club subovoid, nearly three times longer than wide. Prothorax subglobular, as long as wide (LP/WP 1.0), coarsely granulated with sparse minute pubescence, widest at mid-length, weakly convex, with a faint groove along midline reaching only mid-length and with the following scaly markings of metallic golden-yellow, round scales: a) thin band approximately 1/6 length of pronotum along apical margin, b) transverse band across entire width just slightly behind mid-length and c) lateroventral stripe before the coxa, confluent with anterior marginal band and transverse band at mid-length. Elytra short, subovate (LE/WE 1.25), wider and longer than prothorax , subglabrous, weakly convex, coarsely punctured, each puncture with light-coloured, short seta; each elytron with the following scaly markings; a) broad basal band nearly twice as broad as pronotal bands extending from suture to lateral margin, b) broad transverse medial band across entire width from suture towards lateral margin, c) subtriangular patch at apex and d) band along lateral margin confluent with basal and medial bands and subtriangular apical patch. Apical declivity along suture without scales, but with sparse golden-coloured suberect short hairs which continue and become denser towards apex. Legs with moderately clavate femora. Femora covered with recumbent brown hairs. Tibiae weakly serrate along inner margin with suberect, brown bristles along inner margin and subrecumbent brown hairs along outer margin. Fore and mid-tibiae bearing mucro at apex. All tarsomeres densely pubescent dorsally. Coxa with light-coloured recumbent hairs. Mesoventrite with sparse light-coloured, recumbent hairs. Metaventrite and ventrite I moderately depressed on disc, with light-coloured, adpressed hairs and yellow ochre, round scales towards lateral margins. Ventrites II–IV with sparse light-coloured, adpressed hairs. Ventrite V very weakly convex, densely punctured and with dense, long, light-brown adpressed hairs.Male genitalia as shown in Fig. Female. Dimensions (in mm): N = 4. LB 8.5–9.5 (â: 8.75), LR 1.5–1.8 (â: 1.58), WR 1.2, LP 2.8–3.0 (â: 2.85), WP 2.9–3.0 (â: 2.93), LE 5.7–6.5 (â: 5.9), WE 4.0–4.5 (â: 4.13).Females differ from males by the following characters: a) pronotum slightly longer than wide in females (LP/WP 0.96-1.0) than in males, b) elytra slightly longer and wider  than in males, c) elytral apex more pointed and with denser hairs at apex and d) posterior elytral marking imperfectly subtriangular. Otherwise, females similar to males.Metapocyrtusjumawani sp. nov. is related to Metapocyrtustagabawa Cabras, Bollino & Medina, 2020 from Toril, Davao City and Wao, Lanao del Sur and Metapocyrtuslatifasciatus Cabras, Bollino & Medina, 2020 from Cotabato, Sarangani and Davao del Sur, but differs on the broader pronotal and elytral markings and the shape of the aedeagus. M.jumawani sp. nov. differs from M.tagabawa for having broader transverse pronotal mark and basal and medial transverse bands, as well as banded triangular marks at the apical third of the elytra; whereas it differs from M.latifasciatus by having thick transverse basal and medial bands in the elytra instead of one full broad basal band covering almost half of each elytron. At the moment, as the real validity and repartition amongst Metapocyrtus subgenera requires a complete revision, thus we avoided subgeneric assignment for this species.The specific epithet is named after Kim Jumawan (Philippines) for his camaraderie and contribution in helping collect the species described herein.Metapocyrtusjumawani sp. nov. is known, so far, only from the Province of Davao de Oro.Cabras & Medina, 2021sp. n.26AFAEE6-25E9-5085-BCAD-C1FEAC3FE2E9urn:lsid:zoobank.org:act:ef162a92-14a3-4bc0-8b8d-2d167b56307bType status:Holotype. Occurrence: recordedBy: Local collector; individualCount: 1; sex: male; lifeStage: adult; preparations: card-mounted; disposition: in collection; Taxon: scientificName: Metapocyrtusged; kingdom: Animalia; phylum: Arthropoda; class: Insecta; order: Coleoptera; family: Curculionidae; genus: Metapocyrtus; specificEpithet: ged; taxonRank: species; scientificNameAuthorship: Cabras & Medina, 2021; nomenclaturalCode: ICZN; Location: continent: Asia; islandGroup: Mindanao; country: Philippines; countryCode: PHL; stateProvince: Davao del Sur; municipality: Davao City; locality: Toril; Identification: identifiedBy: AA Cabras; Event: samplingProtocol: beating sheet; year: 2019; month: May; habitat: old growth secondary forest; Record Level: institutionID: UM; collectionID: UM-CRCType status:Paratype. Occurrence: recordedBy: Local collector; individualCount: 5; sex: male; lifeStage: adult; preparations: card-mounted; disposition: in collection; Taxon: scientificName: Metapocyrtusged; kingdom: Animalia; phylum: Arthropoda; class: Insecta; order: Coleoptera; family: Curculionidae; genus: Metapocyrtus; specificEpithet: ged; taxonRank: species; scientificNameAuthorship: Cabras & Medina, 2021; nomenclaturalCode: ICZN; Location: continent: Asia; islandGroup: Mindanao; country: Philippines; countryCode: PHL; stateProvince: Davao del Sur; municipality: Davao City; locality: Carmen; Identification: identifiedBy: AA Cabras; Event: samplingProtocol: hand picking; year: 2019; month: July; habitat: old growth secondary forest; Record Level: institutionID: UM; collectionID: UM-CRCType status:Paratype. Occurrence: recordedBy: Local collector; individualCount: 2; sex: female; lifeStage: adult; preparations: card-mounted; disposition: in collection; Taxon: scientificName: Metapocyrtusged; kingdom: Animalia; phylum: Arthropoda; class: Insecta; order: Coleoptera; family: Curculionidae; genus: Metapocyrtus; specificEpithet: ged; taxonRank: species; scientificNameAuthorship: Cabras & Medina, 2021; nomenclaturalCode: ICZN; Location: continent: Asia; islandGroup: Mindanao; country: Philippines; countryCode: PHL; stateProvince: Davao del Sur; municipality: Davao City; locality: Toril; Identification: identifiedBy: AA Cabras; Event: samplingProtocol: beating sheet; year: 2019; month: May; habitat: old growth secondary forest; Record Level: institutionID: UM; collectionID: UM-CRCType status:Paratype. Occurrence: recordedBy: Local collector; individualCount: 1; sex: female; lifeStage: adult; Taxon: scientificName: Metapocyrtusged; kingdom: Animalia; phylum: Arthropoda; class: Insecta; order: Coleoptera; family: Curculionidae; genus: Metapocyrtus; specificEpithet: ged; taxonRank: species; scientificNameAuthorship: Cabras & Medina, 2021; nomenclaturalCode: ICZN; Location: continent: Asia; islandGroup: Mindanao; country: Philippines; countryCode: PHL; stateProvince: Davao del Sur; municipality: Davao City; locality: Carmen; Identification: identifiedBy: AA Cabras; Event: samplingProtocol: hand picking; year: 2019; month: July; habitat: old growth secondary forest; Record Level: institutionID: UM; collectionID: UM-CRCMale. Dimensions (in mm): N = 2. LB 7.8–8.1 , LR 1.2–1.3 , WR 1.1–1.2 , LP 3.0–3.1 , WP 2.8–2.9 , LE 4.8–5.0 , WE 3.5–3.7 .Habitus as shown in Fig. Integument of elytra black; integument of pronotum, head, scape and legs dark ferruginous; funicle, tarsi, rostrum black. Body surface, rostrum and head weakly lustrous and underside subopaque.Body subglabrous. Head subglabrous, sparsely, minutely pubescent; lateroventral parts with yellow ochre and turquoise round and elliptic scales interspersed with light-coloured recumbent piliform scales, forehead between eyes slightly depressed, covered with metallic, yellow ochre and turquoise round and elliptic scales; median groove indistinct. Rostrum strongly rugose especially in basal half, sparsely, minutely pubescent, slightly longer than wide (LR/WR 1.18), dorsum bearing V-shape ridge and minute, light-coloured hairs; lateral surface with recumbent light-coloured hairs and long, light-brown hairs at the anterolateral margin; transverse basal groove distinct, beset with sparse, light yellow ochre and torquiose round scales; dorsal surface moderately convex. Eyes medium-sized and feebly convex. Antenna clavate, scape as long as funicle, moderately covered with fine, light-coloured hairs. Funicular antennomeres I and II of the same length, nearly three times longer than wide; antennomeres III–VII as long as wide; club subovoid, nearly three times longer than wide. Prothorax globular, slightly longer than wide (LP/WP 1.07), weakly granulated with sparse pubescence, widest at mid-length, moderately convex, with a faint groove along mid-line and with the following scaly markings of metallic yellow ochre, turquoise and light blue, round scales: a) thin band approximately 1/6 length of pronotum along anterior margin, b) thin transverse band at mid-length, sometimes interrupted at centre and c) lateroventral stripe before the coxa confluent with the anterior and median bands. Elytra subelliptical (LE/WE 1.37), slightly wider and twice longer than prothorax , subglabrous, striate-punctate, weakly convex, with very minute and sparse light-coloured pubescence. Elytra with the following scaly markings of yellow ochre and turquoise, round scales: a) basal transverse band from suture towards the lateral sides, b) median transverse band, c) subtriangular patch on apical third, d) thick band along lateral margin confluent with basal band, median band and triangular patch at apical third and e) faint stripe along suture. The elytral marks seem to create four squares on the dorsum of the elytra. Apex of elytra with erect bluish piliform scales and light-coloured hairs. Legs with strongly clavate femora. Femora dark ferruginous, but black towards apical half, covered with bluish recumbent piliform scales. Tibiae dark ferruginous, but black towards apex, covered with black piliform scales towards outer surface and black erect hairs on inner margin; serrate along inner margin. Fore and mid-tibiae bearing mucro at apex. Tarsomeres covered with pubescence dorsally. Coxae with light-coloured to greenish recumbent piliform scales. Mesoventrite with sparse and minute light-coloured hairs. Metaventrite with light-coloured suberect hairs and pale yellow to turquoise, round scales at lateral sides. Ventrite I faintly depressed on disc with light-coloured, suberect hairs and sparse light-coloured piliform scales towards sides. Ventrite II with short, light-coloured, suberect hairs and sparse light-coloured piliform scales towards sides. Ventrites III–IV with sparse, light-coloured, short hairs. Ventrite V flattened, apical half finely densely punctured with suberect hairs.Male genitalia as shown in Fig. Female. Dimensions (in mm): N = 2. LB 9.0–9.3 (â: 9.2), LR 1.0–1.1 (â: 1.05), WR 1.2–1.4 (â: 1.3), LP 3.0–3.1 (â: 3.05), WP 3.0–3.1 (â: 3.05), LE 6.0–6.2 (â: 6.1), WE 4.0–4.2 (â: 4.1).Females differ from males by the following characters: a) pronotum more convex, b) elytra obovate (LE/WE 1.47–1.62), longer and wider  than in males, c) apex of elytral declivity with tuft of bristles and e) ventrite I flattened or slightly convex on disc. Otherwise, females are similar to males.Metapocyrtusged sp. nov. belongs to the subgenusMetapocyrtus s.s. for its rostrum with V-shape ridge and rounded dorsolateral edges, as well as elytra laterally elliptical or dorsally ovate. The species is distinct from the rest of Metapocyrtus s.s. by its unique elytral ornamentation.ged is after the acronym of Gloria E. Detoya, Chief Operating Officer/Quality Management Representative of the University of Mindanao for her unwavering support to the Coleoptera Research Center.The specific epithet The new species is, so far, known only in the Province of Davao del Sur.E7836DF0-F336-53BA-B427-4AF672C650C7urn:lsid:zoobank.org:act:54054f64-a5d5-457e-b40b-37165b3588f4Type status:Holotype. Occurrence: recordedBy: Local collector; individualCount: 1; sex: male; lifeStage: adult; preparations: card-mounted; disposition: in collection; Taxon: scientificName: Metapocyrtusflavomaculata; kingdom: Animalia; phylum: Arthropoda; class: Insecta; order: Coleoptera; family: Curculionidae; genus: Metapocyrtus; specificEpithet: flavomaculata; taxonRank: species; scientificNameAuthorship: Cabras & Medina, 2021; nomenclaturalCode: ICZN; Location: continent: Asia; islandGroup: Mindanao; country: Philippines; countryCode: PHL; stateProvince: Davao del Sur; municipality: Davao City; locality: Lamanan; Identification: identifiedBy: AA Cabras; Event: samplingProtocol: handpicking; year: 2018; month: July; habitat: old growth secondary forest; Record Level: institutionID: UM; collectionID: UM-CRCType status:Paratype. Occurrence: recordedBy: Local collector; individualCount: 5; sex: female; lifeStage: adult; preparations: card-mounted; disposition: in collection; Taxon: scientificName: Metapocyrtusflavomaculata; kingdom: Animalia; phylum: Arthropoda; class: Insecta; order: Coleoptera; family: Curculionidae; genus: Metapocyrtus; specificEpithet: flavomaculata; taxonRank: species; scientificNameAuthorship: Cabras & Medina, 2021; nomenclaturalCode: ICZN; Location: continent: Asia; islandGroup: Mindanao; country: Philippines; countryCode: PHL; stateProvince: Davao del Sur; municipality: Davao City; locality: Lamanan; Identification: identifiedBy: AA Cabras; Event: samplingProtocol: handpicking; year: 2018; month: July; habitat: old growth secondary forest; Record Level: institutionID: UM; collectionID: UM-CRCMale. Dimensions (in mm): N = 2. LB 6.8–7.1 , LR 1.0–1.1 , WR 1.0–1.1 , LP 2.0–2.1 , WP 2.0–2.1 , LE 4.8–5.0 , WE 3.0–3.2 .Habitus as shown in Fig. Integument black. Body surface, rostrum, head and underside with weak lustre.Body subglabrous. Head subglabrous, sparsely, very minutely pubescent; forehead between eyes slightly depressed and covered with metallic, light-yellow ochre, round scales; lateral parts with light-yellow ochre, round scales behind eye interspersed with metallic yellow-green, hairlike, elliptical scales; median groove distinct. Rostrum sparsely, minutely pubescent, slightly longer than wide (LR/WR 1.33), dorsum bearing minute, light-coloured recumbent hairs; lateral surface with metallic, yellow-green hair-like scales and long, light-coloured hairs towards anterolateral margin; transverse basal groove distinct; dorsal surface weakly convex with faint V-shaped ridge. Eyes medium-sized and moderately convex. Antenna moderately clavate, scape slightly shorter than funicle, moderately covered with fine, light-coloured hairs. Funicular antennomeres I and II almost of the same length, nearly three times longer than wide; antennomeres III–VII slightly longer than wide; club subovoid, nearly three times longer than wide. Prothorax subglobular, as long as wide (LP/WP 1.0), faintly punctured with sparse minute hairs, widest at mid-length, weakly convex and with the following scaly markings of metallic light yellow ochre and pale green, round scales: a) two medium-sized spots on basal parts, b) two medium-sized spots along apical margin and c) lateroventral stripe before the coxa. Elytra strongly ovate (LE/WE 1.6), wider and longer than prothorax , black, subglabrous, moderately convex, coarsely punctured. Each elytron with the following markings of metallic light-yellow ochre and pale green round scales: a) two sub-basal spots, b) three spots slightly before mid-length, c) three spots along apical third and d) one short apical stripe. Suture along apical declivity with light-coloured piliform scales becoming denser towards apex. Legs with strongly clavate femora. Femora covered with recumbent light-bluish hair-like scales. Tibiae covered with suberect, light-coloured bristles along inner margin and light-coloured recumbent hairs on outer margin; weakly serrate along inner edge. Fore tibiae bearing mucro at apex. Tarsomeres covered with pubescence dorsally. Coxae with light-coloured suberect hair-like scales. Mesoventrite covered with suberect light-coloured hairs. Metaventrite and ventrite I slightly depressed with light-coloured, adpressed bristles and light-yellow ochre, round scales at lateral sides. Ventrites II–V with light-coloured, adpressed bristles. Ventrite V flattened, smooth with dense, recumbent yellow-ochre hairlike-scales.Male genitalia as shown in Fig. Female. Dimensions (in mm): N = 6. LB 7.6–8.5 (â: 8.2), LR 1.0–1.2 (â: 1.13), WR 0.8–1.0 (â: 0.93), LP 2.1–2.5 (â: 2.37), WP 2.4–2.8 (â: 2.67), LE 5.5–6.0 (â: 5.83), WE 4.0–4.2 (â: 4.13).Females differ from males by the following characters: a) pronotum slightly shorter than wide in males (LP/WP 0.88–0.89), b) pronotum subtruncate, c) elytra longer and wider  than in males and with oblique faint ridge on dorsolateral surface before mid-length, d) presence of tuft of piliform scales on elytral declivity and e) elytral apex with triangular projection. Otherwise mentioned, females similar to males.Metapocyrtus (Metapocyrtus) flavomaculata sp. nov. differs from all other species of the subgenus for its unique elytral ornamentation consisting of yellow ochre spots. It bears some superficial resemblance to Metapocyrtus (Metapocyrtus) worcesteri Schultze, 1925 from Zamboanga Province, but can be easily distinguished by the shape of the rostrum and pronotum, the presence of four spots in the pronotum , compared to the two spots at mid-length of M. (M.) worcesteri. The presence of an oblique ridge on the dorsolateral surface before mid-length in the elytra of females of Metapocyrtus (Metapocyrtus) flavomaculata sp. nov. also distinguishes it.Etymology. Latin, flavus = yellow; maculata = spotted. The Latin name refers to the yellow spots on the elytra.The new species is known, so far, in Davao City and Bukidnon.Cabras & Medina, 2021sp. n.24BB00C7-FBA3-5B6A-ABE4-2AEF39242D36urn:lsid:zoobank.org:act:7f58a8b0-4f64-4f23-a798-2c3d377e9c61Type status:Holotype. Occurrence: recordedBy: Local collector; individualCount: 1; sex: female; lifeStage: adult; preparations: card-mounted; disposition: in collection; Taxon: scientificName: Metapocyrtuspseudahirakui; kingdom: Animalia; phylum: Arthropoda; class: Insecta; order: Coleoptera; family: Curculionidae; genus: Metapocyrtus; specificEpithet: pseudahirakui; taxonRank: species; scientificNameAuthorship: Cabras & Medina, 2021; nomenclaturalCode: ICZN; Location: continent: Asia; islandGroup: Mindanao; country: Philippines; countryCode: PHL; stateProvince: Bukidnon; municipality: Lantapan; Identification: identifiedBy: AA Cabras; Event: samplingProtocol: Beating sheet; year: 2018; month: July; habitat: old growth primary forest; Record Level: institutionID: UM; collectionID: UM-CRCFemale. Dimensions (in mm): LB 10.2, LR 1.0, WR 1.0, LP 3.2, WP 3.2, LE 7.0, WE 4.8, N = 1.Habitus as shown in Fig. Integument black. Body surface, rostrum, head and underside with weak lustre.Body subglabrous. Head subglabrous, sparsely, minutely pubescent; forehead between eyes flattish, covered with metallic, golden-yellow and round scales; median groove barely distinct; lateral parts behind eyes with golden-yellow and pale green round scales interspersed with hair-like scales of similar colours. Rostrum sparsely, minutely pubescent, slightly longer than wide (LR/WR 1.33), dorsum and lateral surface bearing minute, recumbent, yellowish hairlike-scales and anterolateral margin with longer, light-brown hairs; transverse basal groove distinct; basal half with pronounced V-shaped ridge beset with metallic golden-yellow, round scales. Eyes medium-sized and feebly convex. Antenna moderately covered with fine, light-coloured hairs. Funicular antennomeres I and II almost of the same length, nearly three times longer than wide. Prothorax subglobular, as long as wide (LP/WP 1.0), mostly punctured, coarsely rugose and punctured especially along middle of dorsum, weakly convex, with distinct mid-line groove. Pronotum with the following scaly markings of metallic golden-yellow and pale green, round scales: a) thin transverse band approximately one seventh of the length of pronotum at anterior margin, b) transverse band across entire width at mid-length slightly thicker than anterior band, nearly confluent with anterior band at middle of dorsum and c) lateroventral stripe before coxa, confluent with anterior and median bands. Elytra short ovate (LE/WE 1.46), wider and longer than prothorax , black, subglabrous, strongly convex; coarsely punctured with very minute and sparse light-coloured, short seta; slightly flattish on basal half of dorsum and with steep apical declivity. Elytra with eight longitudinal scaly stripes of metallic golden-yellow and pale green, round scales beginning shortly from anterior margin and extending towards apex and one longitudinal parasutural stripe from before mid-length towards apical declivity. Longitudinal stripe at striae II extending from anterior margin to apical declivity; stripe at striae II extending from anterior margin to apex of elytra, confluent with stripe at lateral margin; stripe at striae III–VII confluent at apical quarter. Base of apical declivity with brownish tuft of hairs on each elytron. Legs with strongly clavate femora. Femora covered with recumbent light-bluish hair-like scales. Tibiae covered with suberect, light-coloured bristles along inner margin and light coloured recumbent hairs on outer margin; weakly serrate along inner edge. Fore and mid-tibiae bearing mucro at apex. Tarsomeres covered with pubescence dorsally. Coxae with recumbent light-coloured hair-like scales. Mesoventrite covered with metallic and greenish, adpressed hair-like scales. Metaventrite slightly depressed on disc with subrecumbent hair-like scales and light-yellow ochre and pale green round scales at lateral sides. Ventrite I depressed on disc with light-coloured, adpressed hairs. Ventrites II–V with sparse, light-coloured, short hairs. Ventrite V flattened, finely densely punctured with short hairs.Males unknown.Metapocyrtus (M.) pseudahirakui sp. nov. differs from all other species of the subgenus for its unique elytral ornamentation consisting of golden-yellow and pale green longitudinal stripes along the elytral striae. It superficially looks similar to M. (Orthocyrtus) hirakui Cabras, Medina & Bollino, 2021 due to mimicry reasons, but can be distinguished by its rostrum, punctures of the pronotum and the tuft of brownish hairs at the base of the apical declivity. M. (M.) pseudahirakui sp. nov. has rostrum with V-shape ridge and rounded dorsolateral edges, whereas M. (O.) hirakui has a rostrum which is dorsally straight, mostly in a plane with front and, at base, the sides are rectangularly declined.M. (O.) hirakui.Etymology. The specific epithet pertains to its uncanny resemblance to Metapocyrtus (M.) pseudahirakui sp. nov. is known, so far, in Bukidnon.Metapocyrtus spp.Notes on the ecology and mimicry of the new M.jumawani sp. nov. is in Maragusan, Davao de Oro. Davao de Oro  Province in Davao Region and is part of the Eastern Mindanao Biological Corridor (EMBC). It is a long stretch of mountain ecosystems bordering the eastern seaboard of Mindanao. The mountain ecosystem of Davao de Oro, including Cagan Valley, is situated in the east side of Mt. Candalaga range. The biotype is composed of old growth secondary forests, mostly remnants of the logging concessions in the late 1950s. Due to its rugged terrain and inaccessibility for most villagers in the nearby downtown, its forests have remained intact and undisturbed for decades, including its riparian systems, making it an ideal habitat for members of the tribe Pachyrhynchini. The new species was collected on the leaves of Elatostema sp. (Urticaceae).The type locality of M. (M.) ged sp. nov. and M. (M.) flavomaculata sp. nov., both species were collected in Davao City. M. (M.) ged sp. nov. was collected in the secondary forests of Catigan, Toril  flavomaculata sp. nov., on the other hand, was collected in the montane forests bordering Lamanan and Marilog, at an elevation of approximately 1000–1200 m a.s.l. The area where the specimens were collected is a remnant of an old growth forest and the rocks were mostly covered by moss. The new species was collected in a shady area and mostly on wild Impatiens sp.  plants growing on huge mossy rocks. M. (M.) flavomaculata sp. nov. was also observed in Lantapan, Bukidnon which extends the range of the distribution of the species. The northern part of Davao City, such as Calinan, Toril, Lamanan and Marilog, share some common species with Bukidnon, such as the recently-described M.kitangladensis Cabras, Medina & Zhang, 2019 which was found abundant in Bukidnon and was also observed in Marilog and Carmen in Davao City. Lantapan Bukidnon is also the type locality of M. (M.) pseudahirakui sp. nov. The species was collected alongside M. (O.) hirakui Cabras, Medina & Bollino, 2021 and Pachyrhynchustikoi Rukmane, 2016, which were very abundant in the area. At first, it can easily be mistaken for M. (O.) hirakui until further microscopic examination.As for ril Fig.  using a Metapocyrtuspseudahirakui sp. nov. is a classic example of interspecific mimicry within the genus Metapocyrtus, which was mentioned by Pachyrhynchini is quite common, especially between Pachyrhynchus and Metapocyrtus (Schultze 1925). Amongst the four species described here, three are involved in mimicry complexes. M.jumawani sp. nov. is involved in a large and complex mimicry with several species of Metapocyrtus, as well as Pachyrhynchuskraslavae Rukmane & Barševskis 2016 and Pachyrrhynchusmiltoni Cabras & Rukmane, 2016 in Davao de Oro. Metapocyrtuspseudahirakui sp. nov. is in a mimicry complex with M. (O.) hirakui Cabras, Medina & Bollino, 2020, Pachyrhynchustikoi Rukmane, 2016, Doliopsdauvapilsi Barševskis, 2014 and Polycatusmimicus Bramanti, Bramanti, & Rukmane, 2020. Another remarkable mimicry complex is the one observed with M. (M.) flavomaculata sp. nov., wherein five species from the order Coleoptera and one species of Hemiptera were documented sharing the same ornamentations of yellow spots on their bodies within the same vicinity. Amongst the members of this mimicry complex are Pachyrhynchussulphureomaculatus, Pachyrhynchuserichsoni, Alcidodes sp. and the true bug Platynopusmelanoleucus  (Pentatomidae) (Fig. Pachyrhynchini was already noted long ago by Pachyrhynchini was first noted by early naturalists who worked in Southeast Asia such as Wallace and Schultze, who noticed sympatric species of Pachyrhynchini sharing the same integument colours and elytral patterns. The tribe Pachyrhynchini are taking advantage of their colouration as aposematic signals in deterring predators, exploiting predators’ visual system and making them unpalatable to predators (Macrocyrtus, Celebia, Alcidodes, Polycatus, Eupyrgops, Neopyrgops, Coptorhynchus and even the longhorned beetle Doliops by copying the patterns and colourations of the tribe Pachyrhynchini.redators . This de


Correction: BMC Neurol 22, 161 (2022)https://doi.org/10.1186/s12883-022-02681-7Following publication of the original article , an erroIncorrect:https://www.liebertpub.com/doi/epdf/https://doi.org/10.1089/jpm.2021. 0428. Accessed 13 Mar 2022.Intentional sedation as a means to ease suffering: a systematically constructed terminology for sedation in palliative care. Correct:Kremling, A.; Bausewein, C.; Klein, C.; Schildmann, E.; Ostgathe, C.; Ziegler, K. & Schildmann, J. Intentional Sedation as a Means to Ease Suffering: A Systematically Constructed Terminology for Sedation in Palliative Care, J Palliat Med, 2022;25:5The original article  has been


Encarsia Förster, 1878, which is the largest genus of the family Aphelinidae, contains 453 valid species worldwide. Most species of Encarsia with known biology are primary endoparasitoids of Aleyrodidae and Diaspididae.The genus Encarsialongifasciata-group from Malaysia and China are reviewed. This is the first record of this group from Malaysia. Two new species, E.borneensis Geng & Li sp. n. and E.pauroseta Geng & Li sp. n., are described and illustrated. Encarsialongifasciata is newly recorded from Malaysia (Borneo). An updated key to the longifasciata-group species  worldwide is provided.Species of the  Encarsia, amongst them the E.longifasciata-group, together with citrina-, parvella-, cubensis- and meghalayana-group share the character of the fore wing having a clear asetose area around the stigmal vein. This group was defined, established and revised by E.dewa, E.prinslooi, E.arabica, E.longifasciata and E.aleuroplati). E.cassida. Thus, currently six species are included in this group and all of them are known from the Old World tropics region. Here, we report on two new species of the Encarsialongifasciata-group and provide the first record of the species from this group from Malaysia.So far, 108 and 11 species are described from China and Malaysia, respectively . There aSpecimens were collected from Yunnan, China and Borneo, Malaysia using yellow pan traps. Specimens were dissected and mounted dorsally in Canada balsam on slides following the method of Photographs were taken with a digital CCD camera attached to an Olympus BX51 compound microscope and most measurements were made from slide-mounted specimens using an eye-piece graticule. All the specimens listed below are deposited in the Northeast Forestry University, Harbin, China.The following abbreviations are used:Fn flagellar antennomeres.Tn metasomal tergum.YPT yellow pan trapping.NEFU Northeast Forestry University, Harbin, China.NHMUK Natural History Museum, London, UK.Geng & Lisp. n.4BD44D58-BFB8-599B-85B3-3EBC9C825603Type status:Holotype. Occurrence: individualCount: 1; sex: female; lifeStage: adult; Location: country: Malaysia; countryCode: MYS; stateProvince: Borneo; county: Sabah; municipality: Keningau; locality: Jungle Girl Camp; verbatimLatitude: 5°26'55.7" N; verbatimLongitude: 116°27'08.6" E; Identification: identificationID: E432; identifiedBy: Geng Hui; Li Cheng-De; Event: year: 2016; month: August; day: 21-25; Record Level: institutionCode: NEFUFig. 1). Length, mesosoma plus metasoma, 0.57 mm. Head  small, little, referring to the sparse setation of the fore wing disc.E.longifasciata-group species have the maximum marginal fringe length at most 0.7× as long as maximum disc width. This species appears to be similar to E.dewa Pedata & Polaszek having the mid-lobe with two setae, but can be distinguished from the latter by the following: marginal fringe of fore wing as long as width (vs. 0.65-0.7×), scutellum, tegula and metasoma totally pale yellow , F2 0.67× as long as F3 and without longitudinal sensilla ，fore wing with a clear asetose area towards the apex (vs. fore wing with less asetose wing disc towards the apex).This species has unusual fore wings, the disc of which is very sparsely setose, with the maximum width as long as the maximum marginal fringe length. The remaining Subba Rao, 1984019B9B9D-C2E3-5325-82BC-E7350D131944EncarsialongifasciataEncarsialongifasciata Subba Rao: Type status:Other material. Occurrence: individualCount: 2; sex: female; lifeStage: adult; Location: country: Malaysia; countryCode: MYS; stateProvince: Borneo; county: Sabah; municipality: Keningau; locality: Jungle Girl Camp; verbatimLatitude: 5°26'55.7" N; verbatimLongitude: 116°27'08.6" E; Identification: identificationID: E448, E451; identifiedBy: Geng Hui; Event: year: 2016; month: August; day: 21-25; Record Level: institutionCode: NEFUE.longifasciata from Malaysia.Two specimens agree with the descriptions given by


Swallowed topical corticosteroids (STC) are a first-line treatment for eosinophilic esophagitis (EoE) but are not uniformly effective. Dupilumab (DPL), a fully human monoclonal antibody, blocks the shared receptor component for IL-4/IL-13, key and central drivers of type 2 inflammation. In Parts A and B of the phase 3 LIBERTY-EoE-TREET (NCT03633617) study, weekly DPL 300mg improved clinical, symptomatic, histologic, and endoscopic aspects of EoE and was generally well tolerated in adult and adolescent patients (pts) with EoE.To assess the efficacy of weekly DPL 300mg vs placebo (PBO) at Week 24 in pts from Parts A and B with/without prior history of STC use, and from Part B with/without a history of inadequate response, intolerance, or contraindication to STCs.Pts who received STCs for EoE within 8 weeks prior to baseline were excluded from the study. Co-primary endpoints at Week 24 were the proportion achieving peak eosinophil count (PEC) ≤6/high-power field (hpf) and the absolute change in Dysphagia Symptom Questionnaire (DSQ) score. Other secondary endpoints at Week 24 included: % change in PEC; absolute change in Histologic Scoring System (HSS) grade and stage scores and Endoscopic Reference Score (EREFS); % change in DSQ score.At baseline, in Parts A and B combined, 84/122 (69%) and 87/118 (74%) of DPL- and PBO-treated pts had history of STC use. For pts treated with DPL vs PBO PEC≤6/hpf was achieved by 59.5% vs 3.4% of pts with, and 57.9% vs 12.9% without, prior STC use. Difference vs PBO (95% CI) in the absolute change in DSQ score was −13.27  vs −5.21  for pts with/without prior STC use. Difference vs PBO (95% CI) for pts with/without prior STC use were: % change in PEC −80.76 /−84.87 ; absolute change in EoE-HSS grade −0.77 /−0.57  and stage −0.77 /−0.55 ; absolute change in EREFS −3.86 /−2.59 ; % change in DSQ −34.5 /-14.9 . DPL was generally well tolerated in the intent-to-treat population; the most common TEAEs for DPL/PBO were injection-site reactions (37.7/33.3%). In Part B, 38/80 (48%) and 39/79 (49%) of DPL- and PBO-treated pts had inadequate response/intolerance/contraindication to STCs. For DPL vs PBO PEC≤6/hpf was achieved by 55.3% vs 7.7% with, and 61.9% vs 5.0% of pts without, inadequate response/intolerance/contraindication to STC. Difference vs PBO (95% CI) for absolute change in DSQ score was −11.55 /−7.08  for pts with/without inadequate response/intolerance/contraindication to STCs.Conclusion: Regardless of prior STC use, in this pooled analysis from Part A and Part B of the EoE TREET Phase 3 Study, weekly DPL 300mg demonstrated substantial improvements in clinical, histologic, and endoscopic study endpoints at Week 24 in adults and adolescents with EoE.OtherResearch sponsored by Sanofi and Regeneron Pharmaceuticals, Inc.A. Bredenoord Shareholder of: SST, Grant / Research support from: Bayer, Nutricia, SST, Consultant of: Arena Pharmaceuticals, AstraZeneca, Calypso Biotech, Dr Falk, EsoCap, Gossamer Bio, Laborie, Medtronic, RB Pharma, Regeneron Pharmaceuticals, Inc., Robarts Clinical Trials, E. Dellon Grant / Research support from: Research funding; Adare Pharma Solutions, Allakos, GSK, Meritage Pharma, Miraca Life Sciences, Nutricia, Receptos/BMS, Regeneron Pharmaceuticals, Inc., Shire. Educational grant; Allakos, Banner Pharmaceuticals, Holoclara, Consultant of: Abbott, Adare Pharma Solutions, Aimmune Therapeutics, Alivio Therapeutics, Allakos, Arena Pharmaceuticals, AstraZeneca, Banner Pharmaceuticals, Biorasi, Calypso Biotech, Enumeral, EsoCap, Gossamer Bio, GSK, Receptos/BMS, Regeneron Pharmaceuticals, Inc., Robarts Clinical Trials, Salix Pharmaceuticals, Shire/Takeda, A. Lucendo Grant / Research support from: Dr Falk, Regeneron Pharmaceuticals, Inc., Consultant of: Dr Falk, EsoCap, M. Collins Grant / Research support from: Receptos/BMS, Regeneron Pharmaceuticals, Inc., Shire, Consultant of: Allakos, AstraZeneca, BMS, EsoCap, Regeneron Pharmaceuticals, Inc., Shire, A. Khodzhayev Shareholder of: Regeneron Pharmaceuticals, Inc., Employee of: Regeneron Pharmaceuticals, Inc., X. Sun Shareholder of: Regeneron Pharmaceuticals, Inc., Employee of: Regeneron Pharmaceuticals, Inc., K. Patel Employee of: Sanofi, B. Beazley Shareholder of: Regeneron Pharmaceuticals, Inc., Employee of: Regeneron Pharmaceuticals, Inc., A. Shabbir Shareholder of: Regeneron Pharmaceuticals, Inc., Employee of: Regeneron Pharmaceuticals, Inc.


A version of the article with incorrect author order was uploaded to PubMedCentral, and subsequently to PubMed. The corrected article has author order Dhananjay S, Chandhok G., Neumann B., and citation:Dhananjay, S; Chandhok, G; Neumann, B (2022). Novel putative interactors of FZO-1/mitofusin 2 identified using large-scale yeast two-hybrid screening in C. elegans. microPublication Biology. 10.17912/micropub.biology.000674. PMID: 36530473; PMCID: PMC9756088.


In Nazar‐Zadeh et al.,FIGURE 1 Histopathological images of testes in control and treatment groups including A: control, B: Nic, C: Roy 100 mg/kg, D: Roy 150 mg/kg, E: Roy 200 mg/kg, F: Nic + Roy 100 mg/kg, G: Nic + Roy 150 mg/kg, H: Nic + Roy 200 mg/kg. N = 6 mice in each group. Red arrow indicated the interstitial tissue in normal group (A), damaged group (B), and restored group (H). Blue arrow represented the normal germinal epithelium in control group (A), damaged dispersed germinal epithelium in Nic group (B), and repaired damaged epithelium after Roy administration (H). Nic, nicotine; Roy, royal jelly. Scale bar: 100 μm The Authors apologize for this error


Correction: BMC Microbiol 22, 103 (2022)https://doi.org/10.1186/s12866-022-02519-9Following the publication of the original paper , the autAdditional file 1: Table S1. List of strains of Gonium used in this study. Table S2. Specific primers used for genomic PCR for strains of Gonium pectorale  in liquid nitrogen by using a simple cryopreservation module  for two-step cooling in cryopreservation. Figure S1. Mating type determination of four newly established strains of Gonium pectorale  and mating type plus-specific gamete plasma membrane protein gene (FUS1). Actin is an autosomal gene (control). For primers used, see Additional file Figure S2. Full length, unprocessed gel images of the three genes shown in Additional file st, 6th, 11th and 17th lanes). 2nd, 3rd, 4th and 5th lanes: A, B, C and D, respectively, of MID (Additional file th, 8th, 9th and 10th lanes: A, B, C and D, respectively, of Actin (Additional file th, 13th, 14th and 15th lanes: A, B, C and D, respectively, of FUS1 (Additional file


For Dejima, K; Mitani, S (2022). Balancer-assisted outcrossing to remove unwanted background mutations. microPublication Biology. 10.17912/micropub.biology.000561.The authors correct the following:In the reference section, the PubMedID for Dejima et al., is PubMed ID: 29298424 instead of PubMed ID: 34140407Dejima K, Hori S, Iwata S, Suehiro Y, Yoshina S, Motohashi T, Mitani S. 2018. An Aneuploidy-Free and Structurally Defined Balancer Chromosome Toolkit for Caenorhabditis elegans. Cell Rep 22: 232-241. PubMed ID: 29298424.


Nematocarcinusevansi Burukovsky, 2000, N.exilis  and N.machaerophorus Burukovsky, 2003 were newly recorded from the north-western Pacific. The morphological features of these specimens are in concordance with the original description.During two scientific expeditions in the South China Sea and the Kyushu-Palau Ridge area, several specimens of thread-leg shrimp were collected from deep waters. Amongst them, three species, Nematocarcinusevansi and N.machaerophorus were recorded for the second time since their original descriptions and newly found from the South China Sea. Nematocarcinusexilis, collected from the Kyushu-Palau Ridge area, represents a great distribution expansion from the eastern Atlantic and the Mediterranean to the Pacific, making it the fourth Atlantic-Pacific distributed Nematocarcinus species. Their detailed morphological characteristics, colour patterns and partial sequences of the COI and 16S rRNA genes are provided, respectively. Nematocarcinus Milne Edwards, 1881 is the most species-rich genus amongst the caridean shrimp family Nematocarcinidae Smith, 1884, exclusively inhabiting the seafloor in deep-sea . Amongst these, more than 34 species occur in the Pacific, of which about 19 species have been recorded from the north-western Pacific: Nematocarcinusbatei Burukovsky, 2000; N.bituberculatus Chace, 1986; N.chacei Burukovsky, 2002; N.challengeri Burukovsky, 2006; N.combensis Burukovsky, 2000; N.crosnieri Burukovsky, 2000; N.gracilis Spence Bate, 1888; N.kaiensis Burukovsky, 2000; N.longirostris Spence Bate, 1888; N.manningi Burukovsky, 2003; N.nudirostris Burukovsky, 1991; N.parvus Burukovsky, 2000; N.productus Spence Bate, 1888; N.richeri Burukovsky, 2000; N.subtegulisfactus Burukovsky, 2000; N.subtilis Burukovsky, 2000; N.tenuipes Spence Bate, 1888; N.tenuirostris Spence Bate, 1888; and N.undulatipes Spence Bate, 1888 , N.machaerophorus Burukovsky, 2003 and N.undulatipes Spence Bate, 1888. Amongst these, N.machaerophorus had only been recorded in the waters of the islands of Eiao and Ua Pou  at depths of 1000–1100 m; N.evansi had only been recorded from the waters of south-western Australia at depths from 913–916 m, the Indian Ocean , Ministry of Natural Resources of the People’s Republic of China, Hangzhou. Specimens of N.evansi and N.machaerophorus were collected during a cruise within the South China Sea by the R/V “Tan Kah Kee” in June 2020 using a deep-sea Agassiz trawl. The specimens were preserved in 75% ethanol and deposited at the Marine Biological Museum of the Chinese Academy of Sciences (MBM), Qingdao, China.Specimens of https://blast.ncbi.nlm.nih.gov/Blast.cgi) was used to detect the similarity of these sequences to the nucleotide sequence collection database in GenBank (https://www.ncbi.nlm.nih.gov). Genetic distances were calculated using the Kimura 2-parameter model in MEGA X . Total genomic DNA of the specimens was extracted from the fifth pleopod using a TIANamp Marine Animals DNA Kit  according to the manufacturer’s instructions. Partial sequences of COI and 16S rRNA genes were amplified using polymerase chain reaction (PCR) with the primers LCO1490/HCO2198 and 16S-AR/16S-1472, respectively  and thenn MEGA X . All theThe size of the specimens  was measured to the nearest 0.1 mm with a vernier caliper. The following abbreviations were used: St., sampling station; CL, postorbital carapace length; AT, Agassiz trawl; Coll., collector.Burukovsky, 20000F10EE96-A529-5E40-9109-F52D13206252https://www.marinespecies.org/aphia.php?p=taxdetails&id=514308Nematocarcinusevansi : Type status:Other material. Occurrence: individualCount: 1; sex: female; lifeStage: adult (CL 29.5 mm); reproductiveCondition: non-reproductive; establishmentMeans: wild; preparations: damaged animal (ETOH), DNA extract; disposition: in collection; associatedSequences: OP093562, OP093563; occurrenceID: C836B536-48AB-5983-9712-5D897E11FE32; Taxon: scientificNameID: urn:lsid:marinespecies.org:taxname:514308; scientificName: Nematocarcinusevansi Burukovsky, 2000; order: Decapoda; family: Nematocarcinidae; genus: Nematocarcinus; specificEpithet: evansi; taxonRank: species; scientificNameAuthorship: Burukovsky, 2000; nomenclaturalCode: ICZN; taxonomicStatus: accepted; Location: higherGeography: northwestern Pacific; waterBody: Pacific Ocean; country: China; countryCode: China/CN; locality: the South China Sea; verbatimDepth: 734-736 m; verbatimCoordinates: 15.72057°N, 110.77073°E; Identification: identifiedBy: Zhibin Gan; dateIdentified: 12/12/2021; identificationReferences: Burukovsky 2000e, 2003, 2012; identificationRemarks: Nematocarcinusundulatipes Spence Bate, 1888, was collected at the same sampling station and compared with Nematocarcinusevansi Burukovsky, 2000another specimen , ; Event: samplingProtocol: Agassiz trawl; eventDate: 13/06/2020; fieldNumber: St. AT-S58; fieldNotes: Coll. Xu; Record Level: language: en; collectionID: MBM189203; institutionCode: Marine Biological Museum of the Chinese Academy of Sciences (MBM)Body robust, integument hard, surface smooth, shiny. Rostrum straight, slightly over-reaching distal end of antennular peduncle, reaching mid-length of scaphocerite; 0.34 times as long as carapace Fig. A; dorsalEyes normally developed; cornea wider than eye stalk.Third maxilliped not reaching distal end of scaphocerite; ultimate segment 0.71 times as long as penultimate segment, not markedly broadened at middle, armed with four apical spinules; antepenultimate segment shorter than distal two segments combined, armed with 4–6 spines on lateral margin and two distal spines; exopod slightly shorter than antepenultimate segment.First pereiopod slender, over-reaching the end of scaphocerite by distal half-length of carpus. Ischium of first pereiopod with four ventrolateral spines, merus unarmed; ischium of third pereiopod with one distolateral spine. Other pereiopods lost.Posterodorsal margin of third pleomere rounded, continuation of its sides forming an angle of about 120° , the Indian Ocean, at depths from 913–916 m  of the distoventral organ in the sixth pleomere. The slender specimen was consistent with this and, thus, was identified as N.undulatipes, which was previously recorded in the South China Sea . Partial sequences of the COI and 16S rRNA genes of these two samples were deposited in GenBank for future research .The present material is consistent with the original description of N.evansi , especiaN.evansi B. It clohina Sea . FurtherFD94F682-BB81-560F-AF89-870D1CB81760https://www.marinespecies.org/aphia.php?p=taxdetails&id=107574Stochasmusexilis : Nematocarcinusexilis : Type status:Other material. Occurrence: individualCount: 2; sex: 1 female (DY59-I-ROV08), 1 male (DY59-I-ROV05); lifeStage: adult ; reproductiveCondition: non-reproductive; establishmentMeans: wild; preparations: whole animal (ETOH), DNA extract; disposition: in collection; associatedSequences: OP093560, OP093561, OP089177, OP089178; occurrenceID: 6517D2A7-0EA0-5DCF-88CF-EBE8761F09E5; Taxon: scientificNameID: urn:lsid:marinespecies.org:taxname:107574; scientificName: Nematocarcinusexilis ; order: Decapoda; family: Nematocarcinidae; genus: Nematocarcinus; specificEpithet: exilis; scientificNameAuthorship: ; taxonomicStatus: accepted; Location: higherGeography: northwestern Pacific; waterBody: Pacific Ocean; locality: the Kyushu-Palau Ridge area; verbatimDepth: 1956 m (DY59-I-ROV08), 2666 m (DY59-I-ROV05); verbatimCoordinates: 13.330868°N, 134.548018°E(DY59-I-ROV08); 16.931303°N, 134.917863°E (DY59-I-ROV08); Identification: identifiedBy: Zhibin Gan; dateIdentified: 06/08/2021; identificationReferences: Crosnier and Forest, 1973; Abello and Valladares, 1988; Turkay, 1998; Burukovsky, 2012; Event: samplingProtocol: pipet of ROV; eventDate: 20/07/2020, 02/08/2020; fieldNumber: St. DY59-I-ROV05, St. DY59-I-ROV08; fieldNotes: Coll. Gan; Record Level: language: en; collectionID: SRSIO20080316; institutionCode: Sample Repository of the Second Institute of Oceanography (SRSIO)Body moderately slender, integument moderately soft, surface smooth. Rostrum nearly straight, slightly upturned at tip and concave in middle. Rostrum of female specimen over-reaching distal end of antennular peduncle by one-third of its length, reaching to distal one-third of scaphocerite, about half-length of carapace Fig. C; dorsalEyes normally developed; cornea wider than eye stalk.Third maxilliped reaching to distal quarter of scaphocerite; ultimate segment 0.76 times as long as penultimate segment, not markedly broadened at middle, armed with slender apical spinule; antepenultimate segment subequal in length to distal two segments combined, armed with 8–9 spines on lateral margin and two distal spines; exopod reaching to distal two-fifths of antepenultimate segment.First pereiopod slender, overreaching end of scaphocerite by distal one-sixth of carpus; ischium with four ventrolateral spines, merus with 1–2 ventrolateral spines; ischium of second pereiopod with one distolateral spine, merus with 6–9 ventrolateral spines; ischium of third pereiopod with one distolateral spine, merus with 6–7 ventrolateral spines; ischium of fourth pereiopod with 0–1 distolateral spine, merus with 5–6 ventrolateral spines; ischium of fifth pereiopod unarmed, merus with 1–5 ventrolateral spines.Posterodorsal margin of third pleomere rounded, continuation of its sides forming an angle slightly larger than 120° Fig. D. PleuraVentral organ at sixth pleomere formed by two single rows of long plumose setae and two spots; setae rows nearly parallel, extending to end of spots; spots 2.47–2.61 times as long as wide, distance between spots about 2.05 times spots width Fig. G.Telson armed with seven pairs of dorsolateral spines, two pairs of distal spines, without accessory spine Fig. H.Colour, crimson red in female, faint red in male Fig. C–D.Previously known in the eastern Atlantic from 62°17'N to Morocco and Canary Is-lands (900–2300 m) and the Mediterranean Sea at depths between 1033–4765 m. . PresentNematocarcinus species occur in the Indo-west Pacific origin, but only three species, N.ensifer , N.faxoni Burukovsky, 2001 and N.tenuipes , are distributed both in the Atlantic and Pacific Oceans , the antepenultimate segment of the third maxilliped , the pleuron of the fifih pleomere , the telson  and the most important, the distoventral organs of the sixth pleomere , based on which N.exilis. In view of the differences discussed above, we agree with the inference of OP093560, OP093561, OP089177, OP089178).At present, approximately 74.5% of c Oceans . Under tBurukovsky, 2003AB4F7160-5CD6-537C-B0EE-1A1BF2FB3426https://www.marinespecies.org/aphia.php?p=taxdetails&id=586809Nematocarcinusmachaerophorus : Type status:Other material. Occurrence: individualCount: 1; sex: female; lifeStage: adult (CL 23. 5 mm); reproductiveCondition: ovigerous; establishmentMeans: wild; preparations: damaged animal (ETOH), DNA extract; disposition: in collection; associatedSequences: OP093564, OP089181; occurrenceID: 9466BC66-651D-5D94-B040-34418CAA2A52; Taxon: scientificNameID: urn:lsid:marinespecies.org:taxname:586809; scientificName: Nematocarcinusmachaerophorus Burukovsky, 2003; order: Decapoda; family: Nematocarcinidae; genus: Nematocarcinus; specificEpithet: machaerophorus; scientificNameAuthorship: Burukovsky, 2003; taxonomicStatus: accepted; Location: higherGeography: northwestern Pacific; waterBody: Pacific Ocean; country: China; countryCode: China/CN; locality: the South China Sea; verbatimDepth: 811–849 m; verbatimCoordinates: 15.51795°N, 110.95654°E; Identification: identifiedBy: Zhibin Gan; dateIdentified: 06/01/2022; identificationReferences: Burukovsky, 2003, 2004, 2006b, 2012; Event: samplingProtocol: Agassiz trawl; eventDate: 14/06/2020; fieldNumber: St. AT-S59; fieldNotes: Coll. Xu; Record Level: language: en; collectionID: MBM189206; institutionCode: Marine Biological Museum ofthe Chinese Academy of Sciences (MBM)Body moderately slender, integument hard, surface smooth. Rostrum damaged, remaining part nearly horizontal, dorsal margin armed with nine articulated teeth, including four on rostrum proper and five on carapace posterior to orbital margin, space between teeth increasing distally; ventral margin unarmed at remaining part Fig. A. AntennEyes normally developed; cornea wider than eye stalk.Third maxilliped not reaching distal end of scaphocerite; ultimate segment 0.75 times as long as penultimate segment, not markedly broadened at middle, without apical spinule; antepenultimate segment subequal in length to distal two segments combined, armed with six spines on lateral margin and two distal spines; exopod falling short of distal margin of antepenultimate segment.All pereiopods lost.Posterodorsal margin of third pleomere rounded, continuation of its sides forming an angle slightly larger than 120° Fig. B. PleuraVentral organ at sixth pleomere formed by two single rows of long plumose setae and two spots; setae rows cambered laterally, extending to front of spots Fig. D; spots Telson damaged.Previously only known from type locality, the Yeiao and Ua Pou Islands  at depths of 1000–1100 m . PresentNematocarcinus are difficult to identify, not only because of their excessive morphological diversity, but also because of the fragility of the pereiopods and rostrum, which are usually damaged during collection. Nematocarcinus. The present specimen had damaged rostrum and telson that could not be identified through morphology. Fortunately, DNA barcoding provides another efficient way to validate a species. BLAST results indicated a 98.57% match in the COI sequence between the present specimen (OP093564) and the holotype of N.machaerophorus Burukovsky, 2003 , in which only seven nucleotide sites differed. The COI genetic distance between present specimen and the holotype of N.machaerophorus  is 1.8%. The 16S rRNA sequence (OP089181) was identical to that of the holotype of N.machaerophorus . Furthermore, the preserved characteristics of the present specimen, such as the tergum of the third pleomere, the pleura of the fifth pleomere and the distoventral organ, match those of N.machaerophorus, particularly the distoventral organ located on a high tubercle blister of the sixth pleomere. Its setae rows and spots exhibit a similar arrangement to that of the holotype (Species of holotype .Nematocarcinus, being obligate detritophagous and necrophagous, play an important role in the marine material energy cycle (Nematocarcinus shrimp and improving their recorded species diversity. Our report of N.evansi and N.exilis confirms these features are effective in identification. Nevertheless, some badly damaged specimens are beyond accurate morphological identification, such as the specimen of N.machaerophorus in the present research with its rostrum, pereiopods and telson lost during collection. It was unrecognisable based on morphology, but COI and 16S rRNA gene sequence confirmed that it belonged to the species N.machaerophorus. This indicates that the DNA barcoding method is efficient in taxonomy research and biodiversity monitoring. Therefore, adding DNA sequence data as one of the identifying characters for a specimen is significant.Shrimps of the genus gy cycle . They argy cycle . Howevergy cycle . Burukov


The correct name is: Johanna L. A. Paijmans. The correct citation is: Gurke M, Vidal-Gorosquieta A, Paijmans JLA, Wȩcek K, Barlow A, González-Fortes G, et al. (2021) Insight into the introduction of domestic cattle and the process of Neolithization to the Spanish region Galicia by genetic evidence. PLoS ONE 16(4): e0249537.


Correction: BMC Pregnancy Childbirth 22, 355 (2022)https://doi.org/10.1186/s12884-022-04584-4Following publication of the original article , the autThe incorrect author name is: Putora Katharina, Hornung René, Kinkel Janis, Fischer Tina, and Putora Paul Martin.The correct author name is: Katharina Putora, René Hornung, Janis Kinkel, Tina Fischer, and Paul Martin Putora.The author group has been updated above and the original article  has been


Borrelia burgdorferi and Borrelia hermsii.The word "deiminase" is misspelled in the article title. The correct title is: The arginine deiminase system plays distinct roles in Borrelia burgdorferi and Borrelia hermsii. PLoS Pathog 18(3): e1010370. https://doi.org/10.1371/journal.ppat.1010370The correct citation is: Richards CL, Raffel SJ, Bontemps-Gallo S, Dulebohn DP, Herbert TC, Gherardini FC (2022) The arginine deiminase system plays distinct roles in


In the article “Surveillance of Chronic Non-communicable Diseases: thoughts on the roleof national health surveys of Brazil”, doi: 10.1590/SS2237-9622202200010.especial,published on Epidemiology and Health Services, 31(nspe1):e20211048, 2022, in the page 1: Original text:10.1590/SS2237-9622202200010.especialCorrected text:10.1590/SS2237-9622202200013.especial


The publisher apologizes for the error. The correct name is: Norio Yasui-Furukori. The correct citation is: Tokumitsu K, Yasui-Furukori N, Adachi N, Kubota Y, Watanabe Y, et al. (2021) Real-world clinical predictors of manic/hypomanic episodes among outpatients with bipolar disorder. PLOS ONE 16(12): e0262129.


The original publication of this article  containeThe incorrect author name is: Rui Brito.The correct author name is: Rui M. M. Brito.Author nameThe affiliation “Universidade de Coimbra, CQC-IMS, Department of Chemistry, 3004-535 Coimbra, Portugal” was missing from Dr. Brito.Affiliation


People with HIV (PWH) who are initiated on guidelines-recommended first-line INSTI-based antiretroviral therapy routinely achieve rapid virologic suppression; however, those with a high baseline (BL) HIV-1 RNA and/or low CD4 count may be more challenging to manage in the short- and long-term. To further characterize long-term outcomes over 5 years in select subgroups, we analyzed results from two studies examining B/F/TAF as initial treatment stratified by BL HIV-1 RNA and/or CD4 count.Adults with HIV were randomized to receive blinded initial treatment with B/F/TAF versus dolutegravir [DTG]/abacavir/lamivudine (Study 1489) or DTG+F/TAF (1490) for 144 weeks (W) of blinded treatment followed by an optional switch to open-label B/F/TAF for 96W. We present virologic response  and study drug-related adverse events (DRAE) from a pooled analysis of participants originally randomized to B/F/TAF who had BL HIV-1 RNA 100,00-400,000 copies(c)/mL, HIV-1 RNA >400,000 c/mL and/or CD4 count < 200 cells/µL through W240.634 adults  originally randomized to B/F/TAF were included for analysis. At BL, 80 participants had a BL CD4 count < 200 cells/µL and 119 participants had HIV-1 RNA >100,000 c/mL, of whom, 20 had HIV-1 RNA >400,000 c/mL. At W240, virologic suppression was high for the low CD4 count and/or high HIV-1 RNA subgroups (Table). No participant in the final resistance analysis developed virologic resistance to any component of B/F/TAF. Across the subgroups, the most common DRAEs were nausea, headache and diarrhea and there were no serious DRAEs. There was only one discontinuation due to a DRAE in the low CD4 count subgroup, and none in the high HIV-1 RNA subgroup.Initial treatment with B/F/TAF was safe and efficacious over 5 years of follow-up in people with a high BL HIV-1 RNA and/or low CD4 count. These outcomes provide additional evidence that B/F/TAF is an effective and durable regimen for a broad range of PWH, including those with advanced disease.Moti Ramgopal, MD, FACP, FIDSA, Gilead Sciences: Advisor/Consultant|Gilead Sciences: Speakers Bureau|Janssen: Advisor/Consultant|Janssen: Speakers Bureau|Merck: Advisor/Consultant|Merck: Speakers Bureau|ViiV: Advisor/Consultant|ViiV: Speakers Bureau Axel Baumgarten, MD, AbbVie: Honoraria|Gilead Sciences: Honoraria|Janssen: Honoraria|MSD: Honoraria|ViiV: Honoraria Anton Pozniak, MD, FRCP, Gilead: Grant/Research Support|Gilead: Honoraria|Janssen: Grant/Research Support|Janssen: Honoraria|Merck: Honoraria|theratec: Honoraria|ViiV: Grant/Research Support|ViiV: Honoraria Chloe Orkin, MBChB, FRCP, MD, Gilead Sciences: Honoraria|GSK: Honoraria|Janssen: Honoraria|MSD: Honoraria Juan Manuel Tiraboschi, PhD, Gilead Sciences: Advisor/Consultant|Gilead Sciences: Grant/Research Support|Janssen: Advisor/Consultant|Janssen: Grant/Research Support|MSD: Advisor/Consultant|MSD: Grant/Research Support|ViiV Healthcare: Advisor/Consultant|ViiV Healthcare: Grant/Research Support Debbie P. Hagins, MD, FAPCR, AAHIVS, Gilead Sciences: Advisor/Consultant|Gilead Sciences: Grant/Research Support|Gilead Sciences: Speakers Bureau|Janssen: Grant/Research Support|Merck: Advisor/Consultant|Merck: Grant/Research Support|ViiV: Advisor/Consultant|ViiV: Grant/Research Support Hailin Huang, PhD, Gilead Sciences, Inc.: Employer|Gilead Sciences, Inc.: Stocks/Bonds Kristin Andreatta, MSc, Gilead Sciences, Inc: Employee of Gilead Sciences|Gilead Sciences, Inc: Stocks/Bonds Nathan Unger, PharmD, AAHIVP, Gilead Sciences: Employee|Gilead Sciences: Stocks/Bonds Jason Hindman, PharmD, MBA, Gilead Sciences: Employee|Gilead Sciences: Stocks/Bonds Hal Martin, MD, Gilead Sciences: employee|Gilead Sciences: Stocks/Bonds Jared Baeten, MD, PhD, Gilead Sciences: Employee|Gilead Sciences: Stocks/Bonds Olayemi Osiyemi, MD, Gilead: Advisor/Consultant|gsk: Advisor/Consultant|viiv: Advisor/Consultant.


Scientific Reportshttps://doi.org/10.1038/s41598-022-10560-x, published online 29 April 2022Correction to: The original version of this Article contained errors in the spelling of the authors Gerald Haidinger, Judit Simon, Monika Hackl, Eva Schernhammer & Kyriaki Papantoniou which were incorrectly given as G. Haidinger, J. Simon, M. Hackl, E. Schernhammer & K. Papantoniou respectively. The original Article has been corrected.


Correction to:Following publication of the original article [ article , the autThe incorrect name of dietary pattern score is: Planetary Healthy Dietary Index (PHDI).The correct name of dietary pattern score is: Planetary Health Diet (PHD).The incorrect reference is:Cacau LT, De Carli E, de Carvalho AM, Lotufo PA, Moreno LA, Bensenor IM, Marchioni DM. Development and validation of an index based on EAT-lancet recommendations: the planetary health diet index. Nutrients. 2021;13:1698. doi: 10.3390/nu13051698.The correct reference is:https:/eatforum.org/eat-lancet-commission/eat-lancet-commission-summary-report. Accessed 8 Oct 2021.EAT-Lancet Commission. Healthy Diets. In: EAT-Lancet Commission Summary Report about Food Planet Health: Healthy Diets From Sustainable Food Systems. EAT-Lancet Commission. 2019. The original article  has been


International travel facilitates SARS-CoV-2 spread globally. Early detection of variants among arriving international travelers could provide viral information about introduction of variants with differing infectivity, virulence, and vaccine effectiveness, enabling adjustments to treatment and prevention strategies. We initiated a genomic surveillance program at 4 US airports to detect SARS-CoV-2 variants among arriving international travelers.Between November 29, 2021-April 24, 2022, we enrolled arriving air travelers (≥18 years) from flights originating in 16 countries on 5 continents. At four airports, participants self-collected nasal swab samples that were pooled with 5–25 other samples by country of flight. Participants were also given a take-home saliva collection kit; saliva was collected 3-5 days after arrival and mailed back to the laboratory. SARS-CoV-2 reverse transcription–polymerase chain reaction (RT-PCR) was performed on all samples at the laboratory. Positives underwent whole genome sequencing. Demographic, clinical, and travel information was collected.We enrolled 28,656 travelers; median age was 42 years (interquartile range 31-55), 48% were female, and 99.4% self-reported COVID-19 vaccination. Overall, 19%  of pooled and 7.5% (285/3804) of individual samples were positive for SARS-CoV-2. Highest pool positivity of 46% occurred during January 3–10, 2022 . Omicron variant accounted for 97% of sequences . We detected the earliest reporting of Omicron sub-lineages BA.2 and BA.3 (7 and 43 days earlier than reported elsewhere) in the United States and North America, respectively. During April 4–18, we detected an increasing trend of pool positivity among travelers on South African flights, detecting one of the first US-reported BA.4 sub-lineages consistent with early surge of cases in South Africa. Weekly pooled positivity for travelers on South African flights aligned with World Health Organization (WHO)-reported 7-day COVID-19 incidence rates over the same period .This genomic sequencing surveillance platform is a model for traveler-based SARS-CoV-2 genomic surveillance that can be used as an early warning system to detect future outbreaks and pandemics.Renee Wegrzyn, PhD, Ginkgo Bioworks: Stocks/Bonds Robert C. Morfino, MBA, Ginkgo Bioworks Inc: Employee|Ginkgo Bioworks Inc: Stocks/Bonds Scott Milford, n/a, XpresSpa Group, Inc: Stocks/Bonds Scott Milford, n/a, XpresSpa Group, Inc: Stocks/Bonds Ezra T. Ernst, n/a, XpresSpa Group, Inc: Ownership Interest|XpresSpa Group, Inc: Stocks/Bonds William W. Darrow, n/a, XpresSpa Group, Inc: Stocks/Bonds Siyao Lisa Li, n/a, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Thomas Aichele, n/a, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Andrew Rothstein, n/a, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Benjamin Rome, MBA, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Gabrielle Woronoff, PhD, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Keith Robison, PhD, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Dongjuan Dai, PhD, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Allison Hicks, PhD, Ginkgo Bioworks: I am a current employee|Ginkgo Bioworks: Stocks/Bonds Bryan Cosca, n/a, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Alex Plocik, PhD, Ginkgo Bioworks, Inc: Grant/Research Support|Ginkgo Bioworks, Inc: Stocks/Bonds Birgitte Simen, PhD, Ginkgo Bioworks: I am a current employee|Ginkgo Bioworks: Stocks/Bonds.