instruction,input,output
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intravenous azithromycin-induced ototoxicity.,Ototoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Immobilization, while Paget's bone disease was present, and perhaps enhanced activation of dihydrotachysterol by rifampicin, could have led to increased calcium-release into the circulation.",Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Unaccountable severe hypercalcemia in a patient treated for hypoparathyroidism with dihydrotachysterol.,Hypercalcemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: We report two cases of pseudoporphyria caused by naproxen and oxaprozin.,Pseudoporphyria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Naproxen, the most common offender, has been associated with a dimorphic clinical pattern: a PCT-like presentation and one simulating erythropoietic protoporphyria in the pediatric population.",Porphyria non-acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: A 44-year-old man taking naproxen for chronic low back pain and a 20-year-old woman on oxaprozin for rheumatoid arthritis presented with tense bullae and cutaneous fragility on the face and the back of the hands.,Skin fragility
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,BACKGROUND: How to best treat psychotic patients who have had past clozapine-induced agranulocytosis or granulocytopenia remains a problem.,Granulocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: The results suggest that olanzapine may be useful in treating patients with clozapine-induced granulocytopenia without the risk of recurrence of hematologic side effects.,Granulocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prolonged severe 5-fluorouracil-associated neurotoxicity in a patient with dihydropyrimidine dehydrogenase deficiency.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe the side effects of 5-FU in a colon cancer patient who suffered severe mucositis, desquamating dermatitis, prolonged myelosuppression, and neurologic toxicity that required admission to the intensive care unit.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case suggests that BH-AC, a derivative of cytosine arabinoside (1-beta-D-arabinofuranosylcytosine) could be a cause of reversible encephalopathy syndrome.",Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of reversible encephalopathy syndrome in a 16-year-old girl with acute myelogenous leukemia (AML), who is undergoing during consolidation chemotherapy composed of BH-AC (N4-behenoyl-1-beta-D-arabinofuranosyl cytosine) and idarubicin.",Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In one case, the readministration of riluzole was followed by the relapse of hepatitis.",Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the cases of two patients who developed acute hepatitis after taking riluzole at the recommended dose (100 mg daily) for 7 and 4 weeks, respectively.",Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lupus-like syndrome caused by 5-aminosalicylic acid in patients with inflammatory bowel disease.,Lupus-like syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although the two local anesthetics usually do not cause methemoglobinemia, we suspect that the displacement of lidocaine from protein binding by bupivacaine, in combination with metabolic acidosis and treatment with other oxidants, was the reason for the development of methemoglobinemia.",Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methemoglobinemia after axillary block with bupivacaine and additional injection of lidocaine in the operative field.,Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient with chronic renal failure and ischemic heart disease who developed clinically significant methemoglobinemia after an axillary block with bupivacaine and additional injection of lidocaine in the operative field.,Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Detection of activated eosinophils in nasal polyps of an aspirin-induced asthma patient.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An episode of subacute encephalopathy after the infusion of a moderate dose of methotrexate (1500 mg/m2) (MTX) is reported in a young adult with metastastic gastric cancer.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We believe that this represents an unusual case of moderate-dose MTX-induced neurotoxicity in a patient with gastric cancer, which has not previously been reported.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a life threatening side effect of acute epoprostenol infusion (pulmonary edema) in a patient with pulmonary hypertension associated with limited scleroderma and discuss its management and potential etiology.,Pulmonary OOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 14-year-old girl with newly diagnosed SLE developed a pruritic bullous eruption while on prednisone.,Dermatitis bullous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hydroxyurea-induced acute interstitial pneumonitis in a patient with essential thrombocythemia.,Acute Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The clinical course suggests that the interstitial pneumonitis was induced by hydroxyurea.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first case of hydroxyurea-induced acute interstitial pneumonitis reported in the literature.,Acute Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Allergic and irritant contact dermatitis to calcipotriol.,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The present observation suggests, that a batch of different testing doses, including lower testing doses may help to differentiate between an allergic type of contact dermatitis and an irritant type of reaction after treatment with calcipotriol.",Skin irritation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myotonia associated with sarcoidosis: marked exacerbation with pravastatin.,Myotonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pravastatin is associated with myotonia in animals.,Myotonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case suggests that sarcoidosis and pravastatin, two entities not frequently associated with myotonia, may interact in a synergistic manner to produce severe clinical myotonia in humans.",Myotonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Hypersensitivity to aspirin can be manifested as acute asthma, urticaria and/or angioedema, or a systemic anaphylactoid reaction.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Fixed drug eruption is associated with many drugs but this is the first such report with omeprazole.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fixed drug eruption in hands caused by omeprazole.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The objective of this report is to describe a case of fixed drug eruption that occurred during omeprazole treatment.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 26-year-old Japanese man, who had been receiving medical attention for ulcerative colitis for one year, presented with diffuse erythema and pustules on his face and trunk, malaise, and fever up to 39 degrees C one day after the administration of salazosulfapyridine.",Erythema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute generalized exanthematous pustulosis induced by salazosulfapyridine in a patient with ulcerative colitis.,Acute generalised exanthematous pustulosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of acute generalized exanthematous pustulosis (AGEP) induced by salazosulfapyridine in a patient with ulcerative colitis.,Acute generalised exanthematous pustulosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE SUMMARY: A 39-year-old white Jewish schizophrenic man treated with olanzapine developed an elevated serum CK concentration with a peak concentration of 4000 IU/L (normal < 230).,Blood creatine phosphokinase increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: Olanzapine, like other atypical antipsychotic drugs, may cause muscle injury with concomitant elevations of serum CK of muscle origin.",Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Marked elevation of serum creatine kinase associated with olanzapine therapy.,Blood creatine phosphokinase increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of marked elevation of serum creatine kinase (CK) associated with olanzapine therapy.,Blood creatine phosphokinase increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diclofenac-associated hepatitis.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This patient, who had a history of osteoarthritis, had severe hepatitis 5 weeks after being started on diclofenac for increasing pain in the joints.",Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"2-CdA induces lymphocytopenia, which may explain the improvement in this patient's psoriasis.",Lymphopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One case of priapism occurred during heparin therapy for a previous surgical operation to the knee is reported.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Priapism as a complication of heparin therapy.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The association between heparin and priapism is often recognized; abnormal platelet aggregation could play a role in the pathogenesis of this side effect.,Platelet aggregation abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It carries a well-known risk of neutropenia and agranulocytosis, which necessitates the immediate discontinuation of clozapine.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: We report a patient who developed neutropenia on clozapine, but behind the cell count decrease showed to be a diurnal variation of the white blood cells (WBC).",Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute neutrophilic dermatosis induced by all-trans-retinoic acid treatment for acute promyelocytic leukemia.,Acute febrile neutrophilic dermatosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Findings on discontinuation and rechallenge supported the assumption that the hair loss was a side effect of the paroxetine.,Alopecia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hair loss associated with paroxetine treatment: a case report.,Alopecia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on a 37-year-old female who complained of moderate hair loss during paroxetine treatment.,Alopecia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: Patients with insulin allergy may not have complete resolution of their symptoms after standard desensitization, particularly those patients with concomitant protamine allergy.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"METHODS: The patient required insulin desensitization for severe urticaria, angioedema, and occasional wheezing resulting from her insulin dose.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: The purpose of this study was to determine whether desensitization to NPH insulin, as well as standard insulin desensitization, could control allergic symptoms in a patient allergic to both NPH and regular insulin.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patients receiving neutral protamine Hagedorn (NPH) insulin are at increased risk for the development of protamine hypersensitivity.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Protamine allergy as a complication of insulin hypersensitivity: A case report.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She continued to receive regular insulin 4 times per day over the following 3 years with only occasional hives.,Urticaria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient had recurrence of urticaria and angioedema a year and a half later, at which point the NPH was stopped and she was desensitized to regular insulin.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 5-month-old infant became lethargic and poorly responsive after receiving 1 drop of brimonidine in each eye.,Lethargy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An 11-day-old infant became lethargic and apneic after a single drop of brimonidine.,Apnoeic attack
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Apparent central nervous system depression in infants after the use of topical brimonidine.,Depressed level of consciousness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Topical brimonidine may be associated with central nervous system depression in infants.,Depressed level of consciousness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report two cases in which topical brimonidine resulted in apparent central nervous system depression and unresponsiveness in an infant.,Depressed level of consciousness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ceftriaxone was approved in 1997 for the treatment of otitis media despite previous studies that documented an association of ceftriaxone with elevated hepato-biliary enzymes and transient biliary stasis.,Hepatic enzyme increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepato-biliary abnormalities secondary to ceftriaxone use: a case report.,Hepato-biliary abnormalities
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anterior lumbosacral radiculopathy after intrathecal methotrexate treatment.,Anterior lumbosacral radiculopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reported are three children who developed progressive paraparesis after intrathecal methotrexate administration followed by complete or partial recovery.,Progressive paraparesis chronic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 22-year-old black man developed fever, chills, fatigue, night sweats, tender lymphadenopathy, and a generalized, pruritic, macular eruption 3 weeks after starting minocycline therapy for acne.",Chills
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"With the negative viral serologies, the clinical picture was most consistent with an infectious mononucleosis-like syndrome produced by the minocycline ingestion.",Infectious mononucleosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We conclude that the presence of this metabolic defect combined with topical 5-FU (a drug demonstrating a narrow therapeutic index) results in the unusual presentation of life-threatening toxicity after treatment with a topical drug.,Metabolic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We now report the first known cancer patient who developed life-threatening complications after treatment with topical 5-FU and was shown subsequently to have profound DPD deficiency.,Brief resolved unexplained event
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An acute ischaemic event associated with the use of venlafaxine: a case report and proposed pathophysiological mechanisms.,Ischaemic Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The association of venlafaxine treatment with ischaemic events could be explained by its unique pharmacological and haemodynamic properties.,Ischaemic Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of a possible association between an acute cardiovascular event and venlafaxine.,Myocardial ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a case of an elderly woman with a pre-existing history of ischaemic heart disease, who was treated with venlafaxine, and developed acute myocardial ischaemia within the first week of treatment.",Myocardial ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Apparent cyclophosphamide (cytoxan) embryopathy: a distinct phenotype?,Thalidomide embryopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The purpose of this report is to document a new case of in utero CP exposure with multiple congenital anomalies and to establish an apparent CP embryopathy phenotype.,Thalidomide embryopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient: growth deficiency, developmental delay, craniosynostosis, blepharophimosis, flat nasal bridge, abnormal ears, and distal limb defects including hypoplastic thumbs and oligodactyly.",Blepharophimosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In all cases, seizures were controlled by withdrawal of phenytoin and reduction of drug levels.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Paradoxical seizures in phenytoin toxicity.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present three patients with paradoxical seizures; their serum phenytoin levels were 43.5 mcg/mL, 46.5 mcg/mL and 38.3 mcg/mL.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: This case suggests that losartan can induce late-onset angioedema in patients with normal renal function and that the reaction can recur after initial resolution of the symptoms.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Losartan-induced angioedema.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of angioedema associated with losartan administration.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The incidence of angioedema secondary to losartan, an angiotensin II receptor antagonist, is unknown.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a female acromegalic patient in whom multiple hepatic adenomas appeared soon after danazol treatment for uterine fibromatosis.,Acromegaly
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Heparin-induced thrombocytopenia is a rare and serious complication of anticoagulation therapy.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pediatric heparin-induced thrombocytopenia: management with Danaparoid (orgaran).,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"There remains a paucity of information pertaining to alternative anticoagulation strategies for use during cardiopulmonary bypass concomitant with heparin-induced thrombocytopenia, especially in children.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the successful treatment of heparin-induced thrombocytopenia and subsequent hemorrhagic complications postoperatively in a 2-year-old child with Danaparoid (orgaran).,Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Taxane-induced glaucoma.,GlauComa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of glaucoma induced by doxetaxel therapy for metastatic breast cancer.,GlauComa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute hyperphosphatemia caused by sodium phosphate enema in a patient with liver dysfunction and chronic renal failure.,Hyperphosphataemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of acute hyperphosphatemia secondary to rectal administration of sodium phosphate and sodium biphosphate (Fleet enema).,Hyperphosphataemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of recurrent torsades de pointes following treatment with pentavalent antimonial drugs and amiodarone.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Emphasis is given to the differentiation of diphenylhydantoin induced gingival hyperplasia from the angiomatous enlargement of the gingiva before any treatment is planned.,Gingival hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 66-year-old Japanese woman with severe scleroderma developed anemia and thrombocytopenia due to D-penicillamine (D-Pen) treatment, although the leukopenia was not markedly severe.",Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cessation of D-Pen and the start of corticosteroid therapy were followed by recovery from bicytopenia.,Bicytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,In vitro inhibition of hematopoiesis in a patient with systemic sclerosis treated with D-penicillamine.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These findings suggest that bicytopenia in this patient was caused by D-Pen and may be due to different sensitivities in the hematopoietic lineage.,Bicytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 48-year-old woman who was treated for thyrotoxicosis with methimazole developed agranulocytosis.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Postoperative hypocalcemic tetany caused by fleet phospho-soda preparation in a patient taking alendronate sodium: report of a case.,Tetany
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case report describes a patient who was previously prescribed alendronate (Fosamax) and presented with postoperative hypophosphatemia and hypocalcemic tetany after bowel preparation with Fleet Phospho-Soda.,Tetany
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Described here are 2 patients who developed thrombotic microangiopathy of the kidneys after receiving high cumulative doses of the new anticancer drug gemcitabine.,Thrombotic microangiopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombotic microangiopathy with renal failure in two patients undergoing gemcitabine chemotherapy.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The first patient was a 61-year-old man with a 30-year history of fistulizing CD in whom B-cell non-Hodgkin's lymphoma was diagnosed 9 months after treatment with infliximab.,B-cell lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The relationship between infliximab treatment and lymphoma in Crohn's disease.,Lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The second is a 29-year-old man with CD in whom nodular sclerosing Hodgkin's lymphoma was diagnosed 3 weeks after infusion with infliximab.,Hodgkin's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the clinical course of 2 patients with Crohn's disease (CD) in whom lymphoma was diagnosed after treatment with infliximab.,B-cell lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hydroxyurea (HU) and sodium phenylbutyrate (SPB) have been shown to increase fetal hemoglobin (Hb F) levels in patients with thalassemia intermedia.,Lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Of the four patients who responded to HU with an increase in total Hb, all reported symptomatic improvement and three have not required further transfusions.",Hodgkin's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prolonged responses were achieved with low doses of HU (3-10 mg/kg/day) and higher doses were associated with mild reversible hematologic or hepatic toxicity and no further increases in Hb.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Sodium phenylbutyrate was added to treatment with HU in two patients, but failed to produce an increase in total Hb despite increasing Hb F levels.",Haemoglobin increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We conclude that low-dose HU therapy in patients with thalassemia intermedia may increase total Hb levels sufficiently to eliminate the need for transfusions.,Haemoglobin increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe the clinical response, as determined by increases in total Hb and decreased transfusion needs, in five patients with thalassemia intermedia treated with HU alone or in combination with SPB.",Haemoglobin increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 36-y-o patient with schizophrenia, who had consumed gradually increasing quantities of oolong tea that eventually reached 15 L each day, became delirious and was admitted to a psychiatric hospital.",Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,After abstinence from oolong tea his delirium resolved.,Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The clinical course suggests that caffeine, which is present in oolong tea, was mainly responsible for the rhabdomyolysis as well as the delirium, although severe hyponatremia has been reported to cause rhabdomyolysis on rare occasions.",Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The possibility of severe rhabdomyolysis should be considered in a patient with water intoxication due to massive ingestion of caffeine-containing beverages.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report 3 cases of HIV-1 infected patients who experienced symptomatic angiolipomas shortly after starting antiretroviral therapy including the protease inhibitor indinavir.,Angiolipoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Elevated serum triglycerides with clozapine resolved with risperidone in four patients.,Blood triglycerides increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,In two patients clozapine was reinstated after risperidone was discontinued; serum triglyceride levels increased.,Blood triglycerides increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This increase when clozapine was switched to risperidone and vice versa is consistent with our previous report of elevated serum triglyceride levels in clozapine-treated patients.,Blood triglycerides increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intravenous valproate associated with significant hypotension in the treatment of status epilepticus.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first report of significant hypotension associated with intravenous valproate in the treatment of status epilepticus in the pediatric population.",Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of severe hypotension associated with intravenous valproate used to treat status epilepticus in an 11-year-old girl.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,In both patients the rippling phenomena worsened with pyridostigmine treatment but markedly improved after immunosuppression with azathioprine.,Rippling muscle disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A diagnosis of masked theophylline poisoning should be considered in similar situations involving a rapid decrease of insulin requirements.,Poisoning
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Salicylate intoxication was excluded, and theophylline was finally incriminated.",Poisoning
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Theophylline intoxication mimicking diabetic ketoacidosis in a child.,Poisoning
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This compound, used by adults in the child's home, had caused accidental theophylline poisoning, mimicking diabetic ketoacidosis.",Poisoning
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methylene blue in the treatment and prevention of ifosfamide-induced encephalopathy: report of 12 cases and a review of the literature.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ten to 15% of patients treated with ifosfamide develop an encephalopathy.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We conclude that MB is an effective treatment for ifosfamide-induced encephalopathy.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Portal vein thrombosis in a patient with severe haemophilia A and F V G1691A mutation during continuous infusion of F VIII after intramural jejunal bleeding--successful thrombolysis under heparin therapy.,Portal vein Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on a 14-year-old boy with severe haemophilia A who developed a portal vein thrombosis during continuous infusion of F VIII.,Portal vein Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 60-year-old woman with diabetes mellitus (type 2) developed an acute icteric hepatitis-like illness 6 weeks after the initiation of gliclazide therapy.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gliclazide-induced acute hepatitis.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In conclusion, this case strongly suggests that gliclazide can induce acute icteric liver necro-inflammation which may be misdiagnosed clinically as acute viral hepatitis.",Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We believe that this is the first description of acute hepatitis caused by an idiosyncratic adverse reaction to gliclazide or to one of its metabolites.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe the case of acute hepatitis induced by gliclazide, a second generation sulfonylurea.",Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Caution is, therefore, needed to prevent undesired accumulation of TCA that may lead to protracted Cushing's syndrome.",Cushing's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cushing's syndrome persisted more than 6 months while TCA concentrations remained detectable for at least 80 days.,Cushing's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The presented patient was treated with 200 mg TCA and developed Cushing's syndrome 6 weeks later (cortisol and ACTH concentrations were below limits of detection, TCA concentrations were > 3 micrograms/l).",Cushing's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Both had impaired lung function and abnormal computed tomographic scans, and their condition improved when nitrofurantoin was withdrawn and corticosteroid treatment commenced.",Pulmonary function test decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bronchiolitis obliterans organising pneumonia associated with the use of nitrofurantoin.,Bronchiolitis obliterans organising pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The case histories are presented of two patients who developed lung disease associated with the use of nitrofurantoin with histological features of bronchiolitis obliterans organising pneumonia (BOOP), a rare but recognised form of drug induced injury.",HepatitisOrganising pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The favourable outcome in these two patients contrasts with the fatal outcome of the two other reported cases of nitrofurantoin induced BOOP.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The spectrum of nitrofurantoin lung injury continues to widen.,Pulmonary radiation injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The two middle aged women presented with respiratory symptoms after prolonged treatment with nitrofurantoin.,Respiratory disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We suggest that the previous classification of nitrofurantoin induced lung injury into ""acute"" and ""chronic"" injury is an oversimplification in view of the wide variety of pathological entities that have subsequently emerged.",Pulmonary radiation injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intravenous administration of levodopa ameliorated a refractory akathisia case induced by interferon-alpha.,Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The present report illustrates a rare case of refractory akathisia after interferon-alpha treatment and also that levodopa treatment would be theoretically and practically useful in reducing the neurotoxicity associated with interferon-alpha.,Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute erythroid leukemia after cyclophosphamide therapy for multiple myeloma: report of two cases.,Acute erythroid leukemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The development of erythroid leukemia plus carcinoma in these two men suggests mutagenic change secondary to cyclophosphamide therapy.,Neoplasm malignant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Scleroderma-like reaction induced by uracil-tegafur (UFT), a second-generation anticancer agent.",Scleroderma-like reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of UFT-induced scleroderma-like reaction.,Scleroderma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of a scleroderma-like reaction induced by long-term administration of UFT.,Scleroderma-like reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Central nervous system manifestations of an ibuprofen overdose reversed by naloxone.,Central nervous system manifestations
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ibuprofen overdose is usually characterized by GI upset, dizziness, and mild sedation.",Dizziness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of an 11-month-old female infant with a depressed level of consciousness after ingestion of ibuprofen whose mental status markedly improved with administration of naloxone.,Depressed level of consciousness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Flecainide-associated pneumonitis with acute respiratory failure in a patient with the LEOPARD syndrome.,Acute Respiratory failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Flecainide is a rare cause of hypersensitivity pneumonitis, and few cases have been reported.",Hypersensitivity Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a case of interstitial hypoxaemiant pneumonitis probably related to flecainide in a patient with the LEOPARD syndrome, a rare congenital disorder.",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sagittal sinus thrombosis associated with transient free protein S deficiency after L-asparaginase treatment: case report and review of the literature.,Superior sagittal sinus Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of an adult patient with acute lymphoblastic leukemia who presented with repeated transient ischemic attacks followed by a seizure during consolidation treatment with L-asparaginase.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on a young adolescent with benign intracranial hypertension which we attribute to the use of minocycline for acne.,Idiopathic intracranial hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report 2 patients who developed polyarteritis nodosa following vaccination against hepatitis B.,Polyarteritis nodosa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this case, it was suspected that a combination of cigarette smoking, pulmonary fibrosis, and low-dose methotrexate therapy might have promoted the development of lung cancer.",Lung neoplasm malignant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case report illustrates the use of continuous high-dose intracoronary nitroglycerin infusion through a 6 French coronary guiding catheter in the treatment of a patient with cocaine-induced refractory coronary vasospasm.,Arteriospasm coronary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, as illustrated by these and other cases reported to date, the onset of troglitazone-induced liver injury is insidious and temporally variable.",Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It remains to be seen whether the hepatotoxicity associated with troglitazone is a drug-class effect or specific to troglitazone.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Other thiazolidinediones currently in clinical trials may be able to provide the therapeutic benefits of troglitazone without significant hepatotoxicity.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The three reported cases demonstrate that troglitazone is an idiosyncratic hepatotoxin that can lead to irreversible liver injury.,Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Troglitazone-induced fulminant hepatic failure.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nitrofurantoin-induced lung disease: two cases demonstrating resolution of apparently irreversible CT abnormalities.,Lung disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present two cases of nitrofurantoin-induced pulmonary toxicity in which the initial HRCT showed a widespread reticular pattern and associated distortion of the lung parenchyma, thought to represent established fibrosis.",Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fluoxetine-related death in a child with cytochrome P-450 2D6 genetic deficiency.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The medical examiner's report indicated death caused by fluoxetine toxicity.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of a fluoxetine-related death in a child with a confirmed genetic polymorphism of the CYP2D6 gene that results in impaired drug metabolism.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Spinal cord infarction during use of zolmitriptan: a case report.,Spinal cord infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The temporal relationship suggests that the spinal cord infarction may be related to the use of zolmitriptan.,Spinal cord infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE SUMMARY: A 10-year-old white girl with bilateral optic glioma developed a hypersensitivity reaction to carboplatin after nine courses.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This regimen could prove useful for other patients who develop hypersensitivity reactions to carboplatin and allow therapy to continue.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Perinatal vasoconstrictive renal insufficiency associated with maternal nimesulide use.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of an adverse effect of fetal renal circulation by maternal ingestion of nimesulide.,Foetal Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although the t-AML developed following oral etoposide therapy, the child had previously received high-dose, multiagent chemotherapy, and rearrangement of the MLL gene was not demonstrated.",Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Secondary leukemia in a child with neuroblastoma while on oral etoposide: what is the cause?,Leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors present a case of t-AML that developed in a child with metastatic neuroblastoma 18 months after he received oral etoposide, given for palliation purpose.",Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: Cyanamide, an aversive agent widely used in Japan, is known to induce various degrees of hepatic lesion with ground-glass inclusion bodies.",Hepatic lesion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case 2: A 43-year-old male alcoholic remained completely abstinent with cyanamide treatment for 5 years and complained of general fatigue.,Fatigue
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case 3: A 29-year-old female alcoholic complained of general fatigue and a slight fever after 1.5 years of abstinence with cyanamide treatment.,Fatigue
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case 4: A 61-year-old male alcoholic who remained completely abstinent while taking cyanamide for 3 years showed slight elevation of serum transaminases.,Transaminases increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: In some abstainers who take cyanamide for several years, thin septum-like liver fibrosis progresses along with the emergence of ground-glass hepatocytes.",Hepatic fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cyanamide-induced liver dysfunction after abstinence in alcoholics: a long-term follow-up study on four cases.,Hepatic function abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When cyanamide-treated alcoholics relapse into drinking, more severe inflammation develops in the liver.",Inflammation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with an allergy to a macrolide antibiotic was given tacrolimus and developed a sudden cutaneous reaction.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 77-year-old woman with no history of epilepsy presented a probable nonconvulsive status epilepticus while receiving continuous intravenous morphine for back pain relating to vertebral metastasis of a malignant lymphoma.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A generalized tonic-clonic seizure occurred a few minutes after injection of the morphine antagonist naloxone.,Generalised tonic-clonic seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nonconvulsive status epilepticus: the role of morphine and its antagonist.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Spontaneous bacterial peritonitis induced by intraarterial vasopressin therapy.,Peritonitis bacterial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although the literature on the use of risperidone in elderly patients with dementia consists largely of uncontrolled trials, case reports, and chart reviews, it appears that this agent is effective for managing agitation in this population and does so with a low frequency of extrapyramidal symptoms (EPS).",Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three months following splenectomy, multiple abscesses occurred in the muscles of both thighs while the patient was receiving the third course of the CHOP regimen.",Abscess
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After seven months' continuous treatment for suspected tuberculosis with rifampicin and ethambutol a nine-year-old boy developed polyarthritis, rash and hepatitis in association with anti-native DNA antibodies and positive antinuclear factor.",Polyarthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Polyarthritis, hepatitis and anti-native DNA antibodies after treatment with ethambutol and rifampicin.",Polyarthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of normotensive scleroderma renal crisis after high-dose methylprednisolone treatment.,Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,HUS has been reported after several anticancer chemotherapies and most often after mitomycin C-based chemotherapy regimens.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe hemolytic uremic syndrome in an advanced ovarian cancer patient treated with carboplatin and gemcitabine.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a case of HUS in an advanced ovarian cancer patient treated with carboplatin and gemcitabine, and described its favorable outcome after chemotherapy interruption and supportive care with a 1 year follow-up.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"An evaluation of ovarian structure and function should be considered in women of reproductive age being treated with valproate for epilepsy, especially if they develop menstrual cycle disturbances during treatment.",Menstrual disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: Reproductive endocrine disorders characterized by menstrual disorders, polycystic ovaries, and hyperandrogenism seem to be common among women treated with sodium valproate for epilepsy.",Hyperandrogenism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The 3 cases presented here illustrate the development of reproductive endocrine disorders after the initiation of valproate therapy in women with epilepsy.,Endocrine disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe the development of valproate-related reproductive endocrine disorders in women with epilepsy.,Endocrine disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PATIENTS: Three patients developed a reproductive endocrine disorder during treatment with valproate.,Endocrine disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The polycystic changes disappeared from the ovaries in 2 of the women after valproate therapy was discontinued, and the 2 women who had gained weight and developed amenorrhea while being treated with valproate lost weight and resumed menstruating after the change in medication.",Amenorrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, recurrent staphylococcus aureus sepsis developed during CyA therapy.",Staphylococcal sepsis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Recurrent septicemia with lethal outcome during and after cyclosporine therapy in severe ulcerative colitis.,Angiocentric lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 60 year-old woman with chronic renal failure developed acute proximal muscle weakness after receiving a regular dosage of colchicine.,Muscular weakness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Colchicine-induced myopathy in renal failure.,Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Muscle biopsy revealed variation in muscle fiber size and few vacuolated fibers which were features of colchicine-induced myopathy.,Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A third patient experienced disabling neurotoxicity in the extremity of a prior ulnar nerve and tendon transposition after receiving paclitaxel.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Phantom limb pain as a manifestation of paclitaxel neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Physicians should be aware that PLP can occur after initiation of paclitaxel.,Neuropathy peripheral peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe 2 patients with prior amputation who experienced phantom limb pain (PLP) after receiving paclitaxel therapy.,Phantom limb syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Skin manifestations of a case of phenylbutazone-induced serum sickness-like reactions.,Serum sickness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Allergic reaction to gemfibrozil manifesting as eosinophilic gastroenteritis.,Gastroenteritis eosinophilic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of EGE manifested as an allergy to gemfibrozil.,Eosinophilic granulomatosis with polyangiitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the second report of lactic acidosis in a patient on stavudine and lamivudine.,Lactic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present an AIDS patient with severe and prolonged lactic acidosis on stavudine and lamivudine.,Lactic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ataxia caused by propafenone has been reported to the pharmaceutical companies and drug monitoring agencies, but has not been well described or emphasized in the medical literature.",Ataxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A wide variety of adverse central nervous system effects have been reported in association with propafenone; dizziness is the most common.,Dizziness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propafenone-induced ataxia: report of three cases.,Ataxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe 3 elderly patients with moderate to severe ataxia that occurred while they were taking propafenone.,Ataxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 74-year-old man received oral administration of pilsicainide, a pure sodium channel blocker with slow recovery kinetics, to convert paroxysmal atrial fibrillation to sinus rhythm and developed loss of consciousness two days later.",Loss of consciousness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When pilsicainide is prescribed in patients with coronary artery disease or renal dysfunction, close attention must be paid to avoid life-threatening arrhythmias due to high plasma concentrations of the drug.",Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The cases are important in documenting that drug-induced dystonias do occur in patients with dementia, that risperidone appears to have contributed to dystonia among elderly patients, and that the categorization of dystonic reactions needs further clarification.",Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Provocation of non-convulsive status epilepticus by tiagabine in three adolescent patients.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The events of non-convulsive status epilepticus subsided following reduction in tiagabine dosages.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of non-convulsive status epilepticus provoked by tiagabine in adolescent patients.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There have been many reports of probable lithium-induced organic brain syndromes occurring when serum lithium levels are within or close to the therapeutic range.,Organic brain syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When the acute manic state is characterized by marked psychotic symptoms and intense anxiety, it may be associated with increased vulnerability to the development of severe lithium neurotoxicity.",Anxiety
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ritonavir acted as a CYP3A4 inhibitor, diminishing carbamazepine metabolism and provoking an increase in serum levels and clinical toxicity.",Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylaxis to calcitonin.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: We have introduced a case of anaphylaxis by calcitonin that suggest an IgE mediated hypersensitivity reaction.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The intramuscular challenge test with 25 UI of Miacalcic was positive with an immediate anaphylactic reaction.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We introduce a case of a sixty years old woman with several previous episodes of rhinitis, conjunctivitis and perspiration immediately after the administration of salmon calcitonin with nasal spray or intramuscular administration (Calsynar).",Conjunctivitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Minocycline as a cause of drug-induced autoimmune hepatitis.,Autoimmune Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Minocycline-induced autoimmune hepatitis is usually identical to sporadic autoimmune hepatitis.,Autoimmune Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the clinical and liver biopsy morphologic features for 4 patients with minocycline-induced autoimmune hepatitis (group 1).,Autoimmune Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,L-asparaginase-provoked seizures as singular expression of central nervous toxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patients treated with L-asparaginase may present with hemorrhagic and thrombotic cerebrovascular events.,Haemorrhage intracranial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of seizure associated with L-asparaginase therapy but no evidence of hemorrhagic or thrombotic cerebrovascular events.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Eighty-two patients with various malignancies who received imipenem/cilastatin 143 times for neutropenic fever between March 1994 and October 1999 in Department of Pediatric Oncology, Gazi University, were identified.",Febrile Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Incidence of seizures in pediatric cancer patients treated with imipenem/cilastatin.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Proconvulsive tendency of imipenem/cilastatin is one of its well-known side effects.,Proconvulsive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three of these patients had convulsions attributed to imipenem/cilastatin; 3.6% of the patients had seizure, or 2% of imipenem/cilastatin administrations was followed by a seizure attack.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gabapentin-induced mood changes with hypomanic features in adults.,Affective disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two adults who received gabapentin (GBP) and subsequently developed behavioural side effects.,Behaviour disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute pancreatitis in a child with idiopathic ulcerative colitis on long-term 5-aminosalicylic acid therapy.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a 10-year-old boy with ulcerative colitis who developed acute pancreatitis while on long-term treatment with 5-aminosalicylic acid.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Marked visual field constriction appears to be associated with vigabatrin therapy.,Visual field defect
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Electro-oculography, electroretinography, visual evoked potentials, and multifocal electroretinography in patients with vigabatrin-attributed visual field constriction.",Visual field defect
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: Symptomatic visual field constriction thought to be associated with vigabatrin has been reported.,Visual field defect
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The current study investigated the visual fields and visual electrophysiology of eight patients with known vigabatrin-attributed visual field loss, three of whom were reported previously.",Visual field defect
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The field defects and some electrophysiological abnormalities persist when vigabatrin therapy is withdrawn.,Visual field defect
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Depressive symptoms disappeared after interferon therapy was stopped.,Depressed mood
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.,Psychiatric disorder prophylaxis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"While for ribavirin antidepressant effects are not known, we suppose that antidepressants may prevent changes in serotonergic or noradrenergic neurotransmission caused by IFN-alpha.",Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe 2 children with cerebral palsy who suffered significant morbidity immediately after treatment with hyperbaric oxygen.,Multimorbidity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 33-year-old male presented with brown discolouration of the fingernails following the application of 4% hydroquinone in sorbolene cream and 0.1% tretinoin cream to the face intermittently for 9 months.,Nail Pigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nail staining from hydroquinone cream.,Nail discolouration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gangrene of the fingertips after bleomycin and methotrexate.,Gangrene
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This supports the well-reported potential of bleomycin to trigger acral vascular toxicity.,Peripheral vascular disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a 57-year-old man with acral erythrocyanosis progressing to acute digital ischemia and gangrene that developed after combined chemotherapy (bleomycin and methotrexate) used to treat a metastatic squamous cell carcinoma of the hypopharynx.,Gangrene
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diarrhea-associated over-anticoagulation in a patient taking warfarin: therapeutic role of cholestyramine.,Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of significant over-anticoagulation temporally associated with a bout of protracted diarrhea in a patient on warfarin therapy.,Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"MI related to the use of activated and non-activated PCCs predominantly affects young patients who often have no preceding history of, or risk factors for, MI and tends to be associated with large cumulative doses of concentrate.",Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Recombinant VIIa concentrate in the management of bleeding following prothrombin complex concentrate-related myocardial infarction in patients with haemophilia and inhibitors.,Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We have safely used recombinant factor VIIa to treat bleeding in the immediate and long-term period following PCC-related MI.,Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Even after a strict warning, he took another quinine tablet that evening, which triggered his fifth episode of severe thrombocytopenia, and confirmed the etiology of quinine-induced thrombocytopenia.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Occult quinine-induced thrombocytopenia.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Only after three subsequent episodes of severe, symptomatic thrombocytopenia over the next four weeks did he say, upon repeat questioning, that he had continued to take quinine for night leg cramps.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute myeloid leukemia and lung cancer occurring in a chronic lymphocytic leukemia patient treated with fludarabine and autologous peripheral blood stem-cell transplantation.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the exceptional development of AML and lung cancer in a patient with previously diagnosed CLL in minimal residual disease status after fludarabine treatment followed by autologous peripheral blood stem-cell transplantation.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In 2 of the 3 cases the patients were also taking lithium carbonate and beta-blockers, both of which could have contributed to the incontinence.",Incontinence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the present paper the authors describe 2 female patients who developed incontinence secondary to the selective serotonin reuptake inhibitors paroxetine and sertraline, as well as a third who developed this side effect on venlafaxine.",Incontinence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This concerns 2 male patients who experienced incontinence while taking venlafaxine.,Incontinence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case studies in heparin-induced thrombocytopenia.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Type II heparin-induced thrombocytopenia (HIT) is an immunological disorder characterized by antibodies to heparin-platelet factor 4 complexes and a high risk of thrombotic complications.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After several unrevealing medical work-ups, he was found to have a high blood lead level (122 microg/dL); he has a history of scraping and sanding lead paint without adequate protective measures.",Metal poisoning
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It also highlights a current major etiologic question, that is, whether and to what degree lead exposure contributes to the development of hypertension, and raises the issue of whether lead-induced hypertension constitutes a subset of hypertension that is especially amenable to therapy with dietary calcium.",Hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Severe rash, including the Stevens-Johnson syndrome (SJS), is the major toxicity of nevirapine and is described in the package labeling with a prominent, boxed warning.",Severe Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine.,Stevens-Johnson syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Though physicians treating large populations of patients with HIV are well aware of this complication, only one other report of nevirapine-associated SJS has been documented in the dermatology literature.",SJS-Toxic epidermal necrolysis overlap-Toxic epidermal necrolysis overlap
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe 2 cases of SJS related to nevirapine use and review the literature on this newly recognized association.,SJS-Toxic epidermal necrolysis overlap-Toxic epidermal necrolysis overlap
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Oral intake and acarbose were withheld and the ileus spontaneously resolved after 2 days.,Ileus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"There is evidence that the angiotensin II receptor antagonist, losartan, increases urate excretion by reducing reabsorption of urate in the renal proximal tubule.",Blood uric acid increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atrial fibrillation occurring in a patient taking etanercept plus methotrexate for rheumatoid arthritis.,Atrial fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A review of the literature revealed two other cases of hepatic angiosarcoma in patients after long-term cyclophosphamide treatment.,Hepatic angiosarComa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatic angiosarcoma occurring after cyclophosphamide therapy: case report and review of the literature.,Hepatic angiosarComa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We propose that cyclophosphamide be added to the list of exposures potentially associated with hepatic angiosarcoma.,Hepatic angiosarComa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"ARA-C is frequently associated with dermatologic toxicity, but this is only the second case of toxic epidermal necrolysis described in connection with this drug.",Arthropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On the fifth day after administration of a high dose of ARA-C (2 g/m2 intravenously every 12 hours), she developed bullous lesions on the hands and soles that disseminated, evolving to necrosis, sepsis, and death on the 22nd day.",Dermatitis bullous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Toxic epidermal necrolysis after the use of high-dose cytosine arabinoside.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a fatal case of toxic epidermal necrolysis (TEN) resulting from a high dose of cytosine arabinoside (ARA-C).,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Quetiapine and obsessive-compulsive symptoms (OCS): case report and review of atypical antipsychotic-induced OCS.,Obsessive-compulsive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The first known report of quetiapine exacerbating OCS in a 43-year-old man with obsessive-compulsive disorder (OCD), trichotillomania, delusional disorder and bipolar II disorder is presented.",Obsessive-compulsive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,He was diagnosed with possible serotonin syndrome; his symptoms resolved after clomipramine was stopped but before clozapine was restarted eight days later.,Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report on the possible development of serotonin syndrome in a patient receiving clomipramine after clozapine was withdrawn from the treatment regimen.,Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Possible serotonin syndrome associated with clomipramine after withdrawal of clozapine.,Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The day after clozapine was stopped, while he was still receiving clomipramine 150 mg/d, he began behaving oddly, started sweating profusely, shivering, and became tremulous, agitated, and confused.",Agitation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Quinine induced coagulopathy--a near fatal experience.,Coagulopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The cause of his bleeding was a severe thrombocytopoaenia, induced by chronic ingestion of quinine.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dose-dependent olanzapine-associated leukopenia: three case reports.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"These cases suggest the possibility that, in some patients, leukopenia or agranulocytosis during olanzapine treatment might be dose-related.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report three cases of patients who developed leukopenia during olanzapine treatment.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Differential diagnoses included ocular rosacea with cicatrizing conjunctivitis and 5-FU-induced ectropion.,Ectropion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: Patients with 5-FU-induced ectropion experience tender, red, scaled lids, making contact lens wear difficult.",Ectropion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ectropion secondary to bolus injection of 5-fluorouracil.,Ectropion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Exacerbation of 5-FU dermatologic toxicities in patients with preexisting conditions suggests the importance of aggressive ocular prophylaxis, using frequent ocular lubrication and topical steroid preparations with concurrent medical management of pre-existing dermatologic conditions.",Dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Presented is a case of acute renal failure induced by acetazolamide therapy for glaucoma.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Renal failure associated with acetazolamide therapy for glaucoma.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This sulfonamide like nephropathy should be differentiated from acetazolamide-related calcium phosphate nephrolithiasis.,Nephrolithiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ischaemic colitis in a patient taking meloxicam.,Ischaemic Colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Symptoms and endoscopic lesions quickly regressed within 1 week of meloxicam withdrawal.,Gastric mucosal lesion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient who presented with bloody diarrhoea after 15 mg meloxicam daily for 10 days for osteoarthritis.,Diarrhoea haemorrhagic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We suggest that meloxicam might have intestinal toxic effects when taken in high doses, because of reduced COX-2 selectivity.",Enteritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"As these cases revealed, close monitoring of blood chemistry is mandatory after starting spironolactone, and patients should be advised to stop spironolactone immediately if diarrhoea develops.",Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In patients with chronic heart failure, spironolactone added to conventional treatment may lead to serious and, occasionally, fatal hyperkalaemia.",Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,In some cases this seems to happen because spironolactone causes diarrhoea.,Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Serious adverse events experienced by patients with chronic heart failure taking spironolactone.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient with advanced colonic carcinoma who was treated with concomitant chemoirradiation with oxaliplatin and developed a peculiar dermnatitis in the irradiated field after being exposed to subsequent chemotherapy with oxaliplatin.,Colorectal cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An 11-year-old boy developed a severe enteropathy 2 years after initiation of clofazimine treatment for graft-versus-host disease.,Autoimmune enteropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clofazimine enteropathy caused by crystal deposition can be life-threatening.,Autoimmune enteropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clofazimine enteropathy in a pediatric bone marrow transplant recipient.,Autoimmune enteropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She developed a severe urticarial rash 3 weeks following initiation of therapy with Enoxaparin.,Urticaria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We cared for a patient with progressive renal impairment who presented with blurred vision, QRS broadening and cardiac failure due to chronic cibenzoline intoxication.",Vision blurred
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Indolent aspergillus arthritis complicating fludarabine-based non-myeloablative stem cell transplantation.,Arthritis fungal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe two patients with aspergillus arthritis of the knee joint following fludarabine-based non-myeloablative stem cell transplantation.,Arthritis fungal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: The present findings suggest that fluvoxamine can cause increased libido in some patients.,Libido increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Increased libido in a woman treated with fluvoxamine: a case report.,Libido increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: The aim of this paper is to describe a case of increased libido during fluvoxamine therapy.,Libido increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: The patient, a 27-year-old married Japanese woman with borderline personality disorder, developed an increased libido with the administration of fluvoxamine.",Libido increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The increased libido disappeared after fluvoxamine was discontinued.,Libido increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An infant who developed pancreatitis during meglumine antimoniate treatment for visceral leishmaniasis and who was successfully treated with a combination of allopurinol and ketoconazole is reported.,Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in an infant who developed pancreatitis caused by meglumine antimoniate.,Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: This case report showed that the clinical appearance of Hashimoto's disease after IFN-alpha therapy for chronic C hepatitis in our patient was associated with a specific genetic predisposition (DR5) for this pathology.,Autoimmune thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Further studies are necessary to evaluate whether the study of HLA antigens may be a very useful tool to detect the patients with a predisposition to develop autoimmune thyroiditis, in order to make a early diagnosis of thyroid disorders during the IFN-alpha treatment.",Autoimmune thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hashimoto's disease during interferon-alpha therapy in a patient with pre-treatment negative anti-thyroid autoantibodies and with the specific genetic susceptibility to the thyroid disease.,Autoimmune thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVES: The authors described a case of Hashimoto's disease during interferon-alpha (IFN-alpha) treatment for chronic viral C hepatitis in a patient with the specific genetic susceptibility associated with the thyroid disease.,Autoimmune thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"During dose-finding studies for intravenous proton pump inhibitors omeprazole and pantoprazole, three of six young female volunteers receiving omeprazole and two young female volunteers receiving pantoprazole developed peripheral edema within 8 hr when high doses of the proton pump inhibitors were applied by continuous infusion together with large volumes of fluid.",OOedema peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pheripheral edema was observed in five female patients after taking proton pump inhibitors omeprazole, lansoprazole, or pantoprazole for 7-15 days for peptic acid diseases in recommended standard doses.",OOedema peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Motor fluctuations appear after 2-3 years of levodopa treatment, and affect at least 50% of patients after five years.",On and off phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Significant weight loss is a potential adverse event in patients with rheumatoid arthritis treated with leflunomide.,Weight decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Leflunomide-associated weight loss in rheumatoid arthritis.,Weight decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: We queried 35 rheumatologists at the Robert Breck Brigham Arthritis Center to determine if weight loss had occurred as an adverse event in patients treated with leflunomide between November 1998 and January 2000.,Weight decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To determine the frequency of weight loss in patients treated with leflunomide for rheumatoid arthritis at an arthritis referral center.,Weight decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Five of 70 patients who had begun leflunomide therapy had significant weight loss that could not be linked to other identifiable etiologies.,Weight decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is increasingly recognized that dose adjustment of oral valacyclovir in renal failure is necessary to avoid neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neurotoxicity of valacyclovir in peritoneal dialysis: a pharmacokinetic study.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She developed neurotoxicity with an adjustment dosage of valacyclovir for a cutaneous zoster infection.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Avascular necrosis of the femoral head in patients with prostate cancer treated with cyproterone acetate and radiotherapy.,Osteonecrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case histories of two patients with histologically confirmed adenocarcinoma of the prostate, both of whom had been treated with steroidal anti-androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation, and who subsequently developed femoral head avascular necrosis.",Osteonecrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Levofloxacin induced polymorphic ventricular tachycardia with normal QT interval.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of polymorphic ventricular tachycardia with normal QT interval associated with the oral use of levofloxacin in the absence of other etiologies known to cause these arrhythmias.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"So far, few cases of pulmonary side effects caused by ticlopidine have been reported.",Respiratory disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Special care should be taken when pulmonary symptoms appear in association with ticlopidine treatment.,Respiratory disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ticlopidine-induced interstitial pulmonary disease: a case report.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of interstitial pulmonary disease that occurred together with lymphocytic colitis during treatment with ticlopidine.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient that received methadone for cancer-associated pain developed myoclonus as a side effect.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methadone-induced myoclonus in advanced cancer.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of fatal hyperkalemia owing to succinylcholine administration in a patient with mucositis secondary to chemotherapy.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Succinylcholine-induced hyperkalemia in a patient with mucositis secondary to chemotherapy.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We believe that mucositis was a contributing factor to this case of fatal hyperkalemia after administration of succinylcholine, with a mechanism similar to that reported with thermal injury.",Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cutaneous seeding after ultrasound-guided percutaneous ethanol injection for treatment of hepatocellular carcinoma.,Skin infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of needle-track cutaneous seeding of hepatocellular carcinoma (HCC) after sonographically guided percutaneous ethanol injection (PEI).,Skin infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Adenosine-induced ventricular fibrillation.,Ventricular fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, adenosine shortens the antegrade refractoriness of accessory atrioventricular connections and may cause acceleration of the ventricular rate during atrial fibrillation.",Tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We observed ventricular fibrillation in 2 patients who presented to the emergency department with pre-excited atrial fibrillation and were given 12 mg of adenosine.,Ventricular fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After the dose of methylprednisolone was reduced from 40 mg to 20 mg i.v. q6h and shifted to other anti-asthma treatment by procaterol metered dose inhaler via spacer, the psychotic reaction disappeared a few hours later.",Acute Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Continuous EEG monitoring is helpful in managing seizures that occur as a complication of CBZ OD, after the course of recovery or worsening, and in providing assistance with prognosis.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Massive CBZ OD may produce a reversible encephalopathy that includes cortical hyperexcitability, a profound burst-suppression EEG pattern, and cranial nerve areflexia.",Hyperexcitability
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Massive plasmocytosis due to methimazole-induced bone marrow toxicity.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge this is the first report of pancytopenia due to MMI, where the usual hypoplasia found is replaced by massive plasmocytosis.",Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of fulminant hepatic failure associated with didanosine and masquerading as a surgical abdomen and compare the clinical, biologic, histologic, and ultrastructural findings with reports described previously.",Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report details a case of bilateral avascular necrosis of the femoral heads in a patient receiving 'standard' doses of dexamethasone as part of the antiemetic regimen used in cisplatin-based combination chemotherapy.,Osteonecrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although no coagulation study was done and the Meckel's diverticulum is normally associated with bleeding, the particular intensity of the following hemorrhage may have been favored by metformin.",Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"An obese patient, not diabetic, treated with metformin for some weeks, was referred to us with severe inferior digestive hemorrhage, diagnosed with Meckel's diverticulum.",Gastrointestinal Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Digestive hemorrhage caused by a Meckel's diverticulum in a metformin-treated patient: is there any connection?,Digestive Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ulcer became worse after tobramycin and gentamycin treatment for 2 days.,Ulcer became worse
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac.,Haemorrhage intracranial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The bleeding resolved on discontinuation of APV.,Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the occurrence of spontaneous intracranial bleeding in an human immunodeficiency virus (HIV)-infected adolescent with hemophilia A who was receiving amprenavir (APV).,Haemorrhage intracranial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"According to the Naranjo probability scale, the relationship of gemcitabine treatment with cutaneous eruption in our patient is possible.",Toxic skin eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: We report the first case of gemcitabine-induced LABD.,Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Linear immunoglobulin A bullous dermatosis induced by gemcitabine.,Dermatitis bullous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of linear immunoglobulin (Ig) A bullous dermatosis (LABD) induced by gemcitabine.,Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Twenty-four hours after the administration of gemcitabine, a symmetric, bullous, herpetiform eruption appeared on his trunk and upper limbs.",Dermatitis bullous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Vancomycin is the most frequently implicated drug, but other agents have been reported to cause LABD.",Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although taxol has shown significant activity in advanced ovarian cancer, peripheral neuropathy is likely to become the major dose-limiting toxicity.",Neuropathy peripheral peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A rare case of advanced ovarian carcinoma who developed difficulty walking 25 days after treatment with weekly paclitaxel.,Gait disturbance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of advanced ovarian carcinoma who developed difficulty walking because of marked pain in the lower extremities and loss of proprioception 25 days after treatment with weekly taxol (80 mg/m(2)x3).,Gait disturbance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Relief by naloxone of morphine-induced spasm of the sphincter of Oddi in a post-cholecystectomy patient.,Sphincter of Oddi dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present the case of a patient who had undergone cholecystectomy previously, but in whom morphine given in the Emergency Department precipitated pain consistent with biliary colic; the pain resolved promptly after administration of naloxone.",Biliary colic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myasthenia gravis during low-dose IFN-alpha therapy for chronic hepatitis C.,Myasthenia gravis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with rheumatoid arthritis developed an acute intrahepatic cholestasis after 100 mg of sodium aurothiomalate.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute lung injury associated with 5-fluorouracil and oxaliplatinum combined chemotherapy.,Acute lung injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Diarrhoea, T-CD4+ lymphopenia and bilateral patchy pulmonary infiltrates developed in a male 60 yrs of age, who was treated with oxaliplatinum and 5-fluorouracil for unresectable rectum carcinoma.",Lung infiltration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It is concluded that the aforementioned pathological manifestations were due to chemotherapy and included a pulmonary adverse reaction, a feature never previously associated with oxaliplatinum and 5-fluorouracil regimens.",Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: Accutane a teratogenic prescription drug licensed to treat severe, recalcitrant nodular acne.",Teratogenicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: The estimated number of Accutane prescriptions for reproductive-aged women has more than doubled in the past 10 years; it is the most widely used teratogenic drug in the United States, with approximately 2.5 per 1,000 reproductive-aged women exposed to Accutane in 1999.",Teratogenicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 62-year-old woman treated with pranlukast for 2 months developed interstitial pneumonitis with a high fever.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acute interstitial pneumonia induced by ONO-1078 (pranlukast), a leukotriene receptor antagonist.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An asymptomatic HIV-infected woman experienced right-sided renal colicky pain during treatment with indinavir.,Renal colic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Indinavir-associated nephrolithiasis and chronic interstitial nephritis were the only possible causes identified in this patient.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Papillary necrosis associated with the HIV protease inhibitor indinavir.,Renal papillary necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Physicians should be aware that indinavir nephrolithiasis may cause papillary necrosis.,Nephrolithiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The HIV protease inhibitor indinavir may cause nephrolithiasis and interstitial nephritis.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The renal consequences of indinavir-associated nephrotoxicity are uncertain.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of papillary necrosis in a patient treated with indinavir.,Renal papillary necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe 2 male patients, a 49-year-old with psoriatic arthritis and impaired renal function and a 43-year-old renal transplant recipient, who both sustained a marked decline in glomerular filtration rate in conjunction with a selective inhibitor of cyclooxygenase-2 (COX-2), rofecoxib.",Glomerular filtration rate decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: LTG overdose may result in a severe but reversible encephalopathy, a previously undescribed phenomenon.",Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: A 55-year-old woman became stuporous after overdose with lamotrigine (LTG) and valproic acid (VPA) tablets.,Catatonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report that acute lamotrigine poisoning may result in severe encephalopathy.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Stupor from lamotrigine toxicity.,Stupor
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The cause of death was determined to be acute intoxication by olanzapine, and the manner of death was accidental.",Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This article describes the case of a 25-year-old man found dead at home who had been prescribed olanzapine for schizophrenia.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lichenoid drug eruption to salsalate.,Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This eruption emerged after 1 month of therapy with salsalate, persisted for as long as salsalate was administered, and cleared within 3 weeks of discontinuing the medication.",Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient who experienced a lichenoid eruption after the initiation of salsalate for relief of arthritic pain.,lichenoid eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amphotericin B-induced seizures in a patient with AIDS.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARY: A 46-year-old African-American man experienced recurrent grand mal seizures during intravenous infusion of amphotericin B, then petit mal seizures as the infusion was stopped and the drug concentrations decreased with time.",Generalised tonic-clonic seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Amphotericin B seems to be the probable cause of the seizures.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Despite administration of phenytoin and lorazepam, the seizures persisted and occurred only during amphotercin B administration.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Didanosine also has a potential for inducing seizures.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of multiple episodes of seizure activity in an AIDS patent following amphotericin B infusion.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The time course of events suggested that amphotericin B was the cause of the seizures in this AIDS patient.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To date, only three cases of seizures associated with amphotericin B have been reported in the literature, but healthcare providers should be aware of the potential for this rare adverse effect.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Vocal cord paralysis as a consequence of peritonsillar infiltration with bupivacaine.,Vocal cord paralysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present the case of a 5-year-old girl who developed bilateral vocal cord paralysis following preoperative peritonsillar bupivacaine infiltration.,Vocal cord paralysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 53 year old Greenlandic male was admitted twice over a period of 4 years with a new complete right bundle branch block after ingestion of 10 g and 4 g of carbamazepine respectively.,Bundle branch block right
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carbamazepine induced right bundle branch block in a Greenlandic patient.,Bundle branch block right
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cicatricial entropion associated with chronic dipivefrin application.,Entropion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Cicatrization in the substantia propria of the conjunctiva by excessive lymphocytic infiltration after topically administered antiglaucoma drugs including dipivefrin is a possible mechanism of action for entropion.,Entropion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Nine eyes from 6 patients, 74 years to 90 years of age, referred by ophthalmologists for repair of cicatricial entropion after at least 2 years of twice-a-day application of dipivefrin.",Entropion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report patients who presented to the oculoplastics department for repair of cicatrical entropion after topical use of dipivefrin.,Entropion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 34-year-old lady developed a constellation of dermatitis, fever, lymphadenopathy and hepatitis, beginning on the 17th day of a course of oral sulphasalazine for sero-negative rheumatoid arthritis.",Dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It is thought that the clinico-pathological features and chronology of this case bore the hallmarks of the so-called ""3-week sulphasalazine syndrome"", a rare, but often fatal, immunoallergic reaction to sulphasalazine.",Fatal familial insomnia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Interestingly, the use of carboplatin (CBDCA) and VDS in the subsequent treatment course was well tolerated indicating that the SIADH was most likely to have been induced by administration of CDDP.",Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Syndrome of inappropriate secretion of ADH (SIADH) following cisplatin administration in a pulmonary adenocarcinoma patient with a malignant pleural effusion.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following systemic chemotherapy with cisplatin (CDDP) and vindesine (VDS).,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After extensive neurological 'work up', we realized that the anisocoria was related to the transdermal scopolamine patch that we had prescribed for weaning off the opioid.",Anisocoria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anisocoria from transdermal scopolamine.,Anisocoria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,De novo absence status of late onset following withdrawal of lorazepam: a case report.,Petit mal epilepsy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The aim of this report is to describe the clinical and electroencephalographic findings seen in an elderly woman without previous history of seizures who developed a nonconvulsive generalized status epilepticus following acute withdrawal of lorazepam.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Recognizing early signs of HMSN, such as areflexia and pes cavus deformity, can prevent severe neurotoxicity of polychemotherapy by avoiding vincristine.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The disease predisposes to severe vincristine neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 31-year-old women with recurrent Hodgkin's lymphoma and unrecognized HMSN-1 who developed severe motor neuropathy 3 weeks after the first cycle of treatment including 2 mg of vincristine.,Hodgkin's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute asymptomatic hepatitis in a healthy normal volunteer exposed to 2 oral doses of amodiaquine and artesunate.,Asymptomatic viral Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report describes an unexpected drug-induced hepatitis in a previously healthy young woman exposed to 2 doses of amodiaquine and artesunate.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).,Systemic allergic contact dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient who had a systemic allergic contact dermatitis to 8-MOP develop during her second course of PUVA treatment for psoriasis.,systemic allergic contact dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 33-year-old man with a history of recreational benztropine abuse presented to the emergency department with confusion, abdominal pain, and distention.",Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Agranulocytosis and granulocytopenia associated with quetiapine.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: Although a definite association has not been proven, clinicians should be aware of the possibility of agranulocytosis while using quetiapine.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Quetiapine was associated with leucopenia in two patients and clinically apparent agranulocytosis in one patient.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: There is very little published information regarding ofloxacin-induced toxic epidermal necrolysis.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, a large case-control study included three cases of either Stevens-Johnson syndrome or toxic epidermal necrolysis associated with ofloxacin use, but no details of the cases were given.",Stevens-Johnson syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is hoped that this case report creates awareness that ofloxacin-induced toxic epidermal necrolysis is possible.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a fatal case of toxic epidermal necrolysis in a man who was treated with oral ofloxacin for epididymitis.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ofloxacin: a probable cause of toxic epidermal necrolysis.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report rules out other causes of toxic epidermal necrolysis and implicates ofloxacin in what appears to be an atypical presentation of drug-induced toxic epidermal necrolysis.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A boy with chronic neutropenia and recurrent inflammatory skin lesions developed multiple erythematous nodules following administration of G-CSF.,Milker's nodules
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A girl with cystic fibrosis and cyclic neutropenia developed an erythematous papular eruption without fever or neutrophilia 7 months after commencing therapy with G-CSF.,Rash erythematous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neutrophilic dermatoses in two children with idiopathic neutropenia: association with granulocyte colony-stimulating factor (G-CSF) therapy.,Neutrophilic dermatosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Painful neutrophilic skin lesions were observed in two children receiving granulocyte colony-stimulating factor (G-CSF) for treatment of idiopathic neutropenia.,Neutrophilic dermatosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We believe that these skin eruptions belong to a spectrum of neutrophilic dermatoses that can be induced or aggravated by G-CSF therapy.,Neutrophilic dermatosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There is a putative role of liothyronine administration in precipitating or activating hyperthyroidism.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Triiodothyronine-induced thyrotoxicosis in ophthalmic Graves disease.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case report describes the development of asymptomatic visual field defects (VFDs) in a psychiatric patient with bipolar disorder receiving adjunctive tiagabine treatment.,Visual field defect
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary toxicity with mefloquine.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the second report of acute lung injury and diffuse alveolar damage caused by mefloquine.,Acute lung injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This report presents a case of acute lung injury developing within hours after administration of mefloquine for a low-level Plasmodium falciparum malaria, which was persistent despite halofantrine therapy.",Acute lung injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An adult male presented with central blindness after ingesting methanol.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversal of severe methanol-induced visual impairment: no evidence of retinal toxicity due to fomepizole.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Extra caution should be taken in using octreotide or its long-acting analog in patients otherwise predisposed to intrahepatic bile stasis.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gallstones and bile sludge are common side effects of octreotide therapy but rarely become symptomatic or require treatment.,Cholelithiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatolithiasis (intrahepatic stone) during octreotide therapy for acromegaly: a case report.,Hepatolithiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first reported case of hepatolithiasis during octreotide therapy.,Hepatolithiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of hepatolithiasis (intrahepatic stone) complicated by gram-negative sepsis in a 37 year old male with acromegaly being treated with octreotide.,Hepatolithiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, in the mid-to-late 1980s, a series of letters to the editor and case reports announced an association between tamoxifen therapy in women with breast cancer and the development of endometrial carcinoma.",Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this healthy population, the relative risk of developing endometrial carcinoma in the tamoxifen arm was 2.54, although when stratified by age, in women over 50, the risk grew to 4.01.",Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"INH, which is a leading cause of drug eruptions in the above group of drugs was withdrawn.",Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Isonicotinic acid hydrazide induced anagen effluvium and associated lichenoid eruption.,Diffuse alopecia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Such anagen effluvium with lichenoid eruption following INH therapy has not been observed previously.,Diffuse alopecia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Linear IgA bullous dermatosis occurring after carbamazepine.,Linear IgA disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient who experienced LABD shortly after starting carbamazepine therapy.,Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After a second dose of metoclopramide, these symptoms recurred and were associated with confusion, agitation, fever, diaphoresis, tachypnea, tachycardia, and hypertension.",Agitation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Clinicians should be aware of a risk of serotonin syndrome with serious extrapyramidal reactions in patients receiving sertraline or venlafaxine when metoclopramide is coadministered even in a single, conventional dose.",Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.,Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Serotonin syndrome caused by selective serotonin reuptake-inhibitors-metoclopramide interaction.,Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"She was administered metoclopramide because of nausea and, within 2 hours, developed agitation, dysarthria, diaphoresis, and a movement disorder.",Agitation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"She was admitted following a fall and, after being given metoclopramide, developed movement disorder and a period of unresponsiveness.",Movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient suffering from a rare enzyme deficiency developed a malignant neuroleptic syndrome after having been treated with one single dose of haloperidol.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,BACKGROUND: reports on delated cutaneous reactions to captopril have been seldom reported.,Type IV Hypersensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Captopril is an angiotensin-converting enzyme (ACE) inhibitor and their cutaneous side-effects are documented, but little has been published concerning the usefulness of patch test when they occur.",Severe cutaneous adverse reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dermatitis to captopril.,Dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We presented the case of a patient who developed a cutaneous reaction induced by captopril with positive patch test.,Severe cutaneous adverse reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 62-year-old Caucasian man with atrial fibrillation who was taking warfarin reported an episode of hematochezia; his international normalized ratio (INR) was 1.74.,Haematochezia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Warfarin-associated bleeding complication saved life.,Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Warfarin-associated bleeding generally is considered deleterious; however, in our patient it unmasked an early stage of colon cancer and thus may have saved the patient's life.",Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of polymyositis with dilated cardiomyopathy associated with interferon alpha treatment for hepatitis B.,Dilated Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this case, interferon alpha induced polymyositis and cardiomyopathy is diagnosed in a 33-yr-old male patient with history of chronic hepatitis B.",CardioMyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Polymyositis is a rare complication of interferon alpha treatment as a result of immune-modulating role of the drug itself.,PolyMyositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To treat hepatitis B, interferon alpha was administered until the proximal muscle weakness developed.",Muscular weakness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Aggressive endometrial carcinoma in a breast cancer patient treated with tamoxifen with normal transvaginal ultrasonography.,Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since tamoxifen therapy can induce endometrial disorders, surveillance schemes of women taking tamoxifen have been recommended.",Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We described a very atypical case of a high stage, high grade endometrial cancer associated with tamoxifen in a 64-year-old woman with a past history of breast cancer.",Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Beginning ductopenia was present in two, suggesting that itraconazole might be responsible for the occurrence of prolonged drug-induced cholangiopathy.",Biliary tract disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Itraconazole-induced liver injury presents with a cholestatic pattern of injury with damage to the interlobular bile ducts, possibly leading to ductopenia.",Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity related to itraconazole: report of three cases.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: Three patients with apparent itraconazole-induced liver injury were studied.,Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The occurrence of acute hepatitis is best known for ketoconazole.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report on three patients who developed acute liver damage during therapy with itraconazole, and in whom liver biopsy specimens were obtained.",Hepatocellular injury neonatal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We suggest that itraconazole should be added to the list of drugs that may be responsible for a drug-induced vanishing bile duct syndrome.,Vanishing bile duct syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"With itraconazole, hepatotoxic reactions have only very rarely been reported, and histologic data are lacking.",Hepatitis toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombotic stroke associated with the use of porcine factor VIII in a patient with acquired haemophilia.,Thrombotic Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We have recently encountered a patient with acquired haemophilia who developed a thrombotic left middle cerebral artery distribution stroke while being treated with pFVIII.,Thrombotic Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We speculate that platelet activation induced by pFVIII may have contributed to thrombosis and suggest that pFVIII be used with caution in elderly patients with pre-existing cardiovascular risk factors.,Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cutaneous sarcoidosis during interferon alfa and ribavirin treatment of hepatitis C virus infection: two cases.,Cutaneous Sarcoidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There have been more than 20 observations of the appearance or aggravation of this granulomatosis with interferon alfa and more recently with the combination of interferon alfa plus ribavirin.,Chronic granulomatous disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two new cases of sarcoidosis in two patients with hepatitis C virus infection treated with interferon alfa and ribavirin.,Sarcoidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Although mirtazapine offers clinicians a combination of strong efficacy and good safety, we suggest bearing SS in mind when prescribing this drug, especially in frail, elderly patients with underlying chronic conditions.",Systemic sclerosis pulmonary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: A review of the cases of SS with implication of mirtazapine as the cause was performed.,Systemic sclerosis pulmonary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: To document a case of serotonin syndrome (SS) associated with mirtazapine monotherapy, review the previously reported cases of SS associated with this tetracyclic antidepressant, and discuss the possible pathogenic mechanisms leading to this serious adverse drug reaction.",Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe serotonin syndrome induced by mirtazapine monotherapy.,Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary toxicity secondary to procarbazine.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 64-year-old man presented with proteinuria during postoperative interferon (IFN)-beta therapy against malignant melanoma.,Proteinuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Minimal change nephrotic syndrome developing during postoperative interferon-beta therapy for malignant melanoma.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,To our knowledge this is the first report that demonstrates histological abnormalities of the glomerulus associated with postoperative IFN-beta therapy for the malignant melanoma.,Glomerular vascular disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Clinicians should be aware of the possible association of thrombocytopenia with lansoprazole and discontinue the drug if thrombocytopenia becomes apparent.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: After exclusion of other causes, the onset of thrombocytopenia after administration of lansoprazole, the resolution of the adverse reaction after discontinuation of the drug, and the fact that no other medicines were introduced during this time frame lead us to believe that this was most likely an idiosyncratic thrombocytopenic response to lansoprazole.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"He was started on oral lansoprazole 60 mg twice daily and, on hospital day 2, his platelet count decreased to 102 x 10(3)/mm(3); on hospital day 3, the platelet count was 36 x 10(3)/mm(3).",Platelet count decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lansoprazole-induced thrombocytopenia.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe a case of thrombocytopenia associated with the administration of lansoprazole.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To date, this is the first reported case of what appears to be isolated thrombocytopenia associated with lansoprazole.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Life-threatening anaphylactoid reaction to amifostine used with concurrent chemoradiotherapy for nasopharyngeal cancer in a patient with dermatomyositis: a case report with literature review.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient suffered a life-threatening anaphylactoid reaction to amifostine.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Agranulocytosis during clozapine therapy.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Granulocytopenia and agranulocytosis are considered among the most dangerous adverse effects of clozapine.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The female patient received clozapine in a daily dose of 400 mg, which induced agranulocytosis after 2 months.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The male patient was treated with 225-mg/day clozapine and the time to the diagnosis of agranulocytosis was 6 weeks.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 53-year-old man developed NMS without rigidity while taking olanzapine.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atypical neuroleptic malignant syndrome associated with olanzapine.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARY: We report the case of a 31-year-old patient hospitalized due to behavioral alterations and treated with oral zuclopenthixol, an antipsychotic from the thioxanthene family, who developed an acute, painful erection.",Painful erection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Priapism is an uncommon but potentially serious adverse effect of zuclopenthixol that practitioners, as with many other antipsychotics, should be aware of.",Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: The occurrence of priapism in our patient was related to zuclopenthixol.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To present a single case of zuclopenthixol-induced priapism and a literature review.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Priapism associated with zuclopenthixol.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The capacity of zuclopenthixol to induce priapism is thought to be due to its antagonist activity on alpha-adrenergic receptors.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After identification of the index patient, additional inquiry revealed that the patient's mother was hospitalized previously for overwhelming sepsis associated with metamizole use.",Sepsis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Metamizole, a nonsteroidal antiinflammatory agent, is prohibited in the United States because of the risk of agranulocytosis but is widely used in Mexico and other countries.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Erythropoietin is beneficial in mitomycin-induced hemolytic-uremic syndrome.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient who developed HUS after treatment with mitomycin C (total dose 144 mg/m2) due to a carcinoma of the ascending colon.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Levofloxacin-induced toxic epidermal necrolysis in an elderly patient.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this case is the first published report of levofloxacin-induced TEN.",Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 31-year-old female developed multiple episodes of grand mal seizures after combination chemotherapy with cisplatin, vinblastine and bleomycin for germ cell ovarian cancer stage Ic.",Generalised tonic-clonic seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Posterior leukoencephalopathy following cisplatin, bleomycin and vinblastine therapy for germ cell tumor of the ovary.",Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After 5 days of treatment with IL-2, the patient developed a hemorrhagic lesion that progressed to toxic epidermal necrolysis, as well as grade 4 pancytopenia.",Hemorrhagic lesion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of cutaneous and hematologic toxicity in a patient treated with IL-2.,cutaneous and hematologic toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Toxic epidermal necrolysis associated with interleukin-2.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case of anaphylactoid reaction due solely to the use of Gelofusine in a patient with non-haemorrhagic hypovolaemia is presented, with a discussion on the management and the use of allergy identification jewellery.",Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gelofusine allergy--the need for identification jewellery.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors describe valproate-induced hyperammonemia and mental status changes in an 88-year-old man, the first known reported case in an elderly patient.",Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Valproate-induced hyperammonemia as a cause of altered mental status.,Altered state of consciousness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Leiomyosarcoma in urinary bladder after cyclophosphamide therapy for retinoblastoma and review of bladder sarcomas.,LeiomyosarComa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The epivodes of NMS occured under treatment with clozapine, risperidone, and amisulpride.",Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 73-year-old woman presented with fever and cough 2 weeks after completing the third cycle of fludarabine for chronic lymphocytic leukemia (CLL).,Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fludarabine induced lung toxicity must be considered in all patients who develop unexplained lung disease while receiving fludarabine.,Lung disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Multiple pulmonary nodules: an unusual presentation of fludarabine pulmonary toxicity: case report and review of literature.,Milker's nodules
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case extends the spectrum of fludarabine pulmonary toxicity to include pulmonary nodules.,Milker's nodules
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, four cases of interstitial pneumonitis associated with fludarabine have been reported in medical literature.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Epoprostenol may be associated rarely with severe erythroderma.,Dermatitis exfoliative generalised
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe erythroderma as a complication of continuous epoprostenol therapy.,Dermatitis exfoliative generalised
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of a patient with pulmonary hypertension and undifferentiated connective tissue disease who, after 2 months of treatment with epoprostenol, presented with rapidly progressive erythema, scaling, nausea and vomiting, and fever.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 50-year-old diabetic and hypertensive male patient is reported who had ticlopidine-induced marrow aplasia partially responsive to colony-stimulating factors and corticosteroids, but experienced complete recovery with cyclosporine.",Febrile bone marrow aplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There is no consensus on the treatment of ticlopidine-induced marrow aplasia.,Febrile bone marrow aplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ticlopidine-induced marrow aplasia treated with cyclosporine.,Febrile bone marrow aplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 53-year-old man developed lower leg edema 4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day.,OOedema peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 75-year-old man developed bilateral lower leg edema 6 months after switching from troglitazone to pioglitazone.,OOedema peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 77-year-old man developed ankle, hand, and facial swelling 2 weeks after starting rosiglitazone.",Peripheral swelling
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two cases of polymorphic ventricular tachycardia induced by the administration of verapamil against paroxysmal supraventricular tachycardia.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Verapamil is widely used for the termination of paroxysmal supraventricular tachycardia (PSVT) with little proarrhythmic effect.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe two cases of PSVT that changed to non-sustained polymorphic ventricular tachycardia after administration of verapamil.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Epsilon-aminocaproic acid and renal complications: case report and review of the literature.,Mydriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a neonate with a seizure disorder who acutely developed pupillary mydriasis secondary to lidocaine overdose.,Mydriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We suggest adding this side effect to the list of untoward effects of lidocaine and to the differential diagnosis of fixed dilated pupils in neonates treated with lidocaine.,Mydriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myelodysplasia terminating in acute myeloid leukemia in a hairy cell leukemia patient treated with 2-deoxycoformycin.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To the best of our knowledge only two previous cases of AML have been linked to treatment of HCL with purine analogs, both with 2-chlorodeoxyadenosine.",Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Peripheral administration of low-dose vasopressin for septic shock should be discouraged because of the risk of ischemic skin complications.,Skin ischemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe a case of severe skin necrosis resulting from peripheral intravenous administration of low-dose vasopressin in a patient with catecholamine-resistant septic shock.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Skin necrosis after extravasation of low-dose vasopressin administered for septic shock.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mitomycin-C induced hemolytic uremic syndrome: a case report.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mitomycin-C is used widely in the treatment of malignancies and is associated with serious dose related adverse effects including the occurrence of hemolytic uremic syndrome.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although vasculitis has been reported in the course of hairy cell leukaemia, it has only rarely been reported as the consequence of cladribine treatment.",Vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Systemic vasculitis complicating hairy cell leukaemia treatment with cladribine.,Vasculitis necrotising
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a 73-year-old woman who developed serious systemic vasculitis with associated thrombocytopenia in the course of treatment with cladribine.,Vasculitis necrotising
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug-induced mammary hyperplasias have been reported as rare complications of D-penicillamine and Neothetazone.,Breast hyperplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gigantomastia induced by bucillamine.,Breast enlargement
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Retrospectively, bucillamine was believed to be the cause of the giant hypertrophy because of its structural similarity to D-penicillamine, which was the subject of an abundance of reports of mammary hyperplasia.",giant hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report the first case of bucillamine-induced giant mammary hyperplasia.,Breast enlargement
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors describe three families in whom the occurrence of FVS in all the siblings strongly suggests hereditary susceptibility to valproic acid-induced adverse outcome.,Foetal anticonvulsant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The fetal valproate syndrome (FVS) is characterized by distinctive facial appearance, major and minor malformations, and developmental delay.",Developmental delay
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Valproate embryopathy in three sets of siblings: further proof of hereditary susceptibility.,Foetal anticonvulsant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Generalised pustular psoriasis induced by cyclosporin a withdrawal responding to the tumour necrosis factor alpha inhibitor etanercept.,Pustular Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a 50-year-old male patient with a 15-year history of psoriasis including mutilating psoriatic arthritis, in whom the withdrawal of cyclosporin A induced a generalised pustular exacerbation and a aggravation of the joint condition.",Arthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The first case concerns a 70-year-old man who developed severe aplastic anemia 7 weeks after treatment with 500 mg of ticlopidine daily.,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The second was an 82-year-old man receiving ticlopidine for 2 years when, during a febrile episode, he was found neutropenic with marrow aplasia.",Bone marrow failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ticlopidine-induced aplastic anemia (TIAA) is considered very uncommon.,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ticlopidine-induced aplastic anemia: two new case reports, review, and meta-analysis of 55 additional cases.",Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When the data of the 57 patients are evaluated, a reversible direct cytotoxic effect of ticlopidine on the pluripotent/bipotent hematopoietic progenitor stem cell is proposed.",Cell-mediated cytotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fixed drug eruption to rofecoxib.,Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Rofecoxib, used for dysmenorrhea, caused a herpetiform fixed drug eruption predominantly involving the lips with classic clinical and histological findings in a red-brown lesion on the dorsal hand.",Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient who had been treated with large doses of thyroid hormone for several years developed features of secondary hypothyroidism after thyroid hormone withdrawal.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: Gemcitabine has mild renal toxicity, but cases of gemcitabine-associated hemolytic-uremic syndrome (HUS) have been reported.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: There are only a few confirmed cases of gemcitabine-associated HUS despite the widespread use of the drug.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gemcitabine-associated hemolytic-uremic syndrome.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Mean time between initiation of gemcitabine therapy and onset of HUS was 7.4 +/- 3.5 months, or 21.9 +/- 10.9 doses of gemcitabine.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: A case is presented of a 45-year-old woman on prolonged gemcitabine treatment for ovarian cancer who developed HUS and recovered after drug discontinuation.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: Including our own patient, a total of 26 cases of gemcitabine-associated HUS were identified.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An amiodarone optic neuropathy has been described.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Biomicroscopy revealed amiodarone corneal deposits.,Corneal deposits
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE REPORT: Soon after initiation of amiodarone HCl (200 mg/day), a 76-year-old man came to us with symptoms of visual ""shining,"" glare, color vision anomalies, and gradually decreased vision.",Colour vision tests abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Visual changes secondary to initiation of amiodarone: a case report and review involving ocular management in cardiac polypharmacy.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"While both amiodarone and digoxin can cause permanent visual changes, the ocular effects are often reversible.",Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Infant twins sustained severe circumoral and pharyngeal burns from a concentrated solution of benzalkonium (Zephiran) chloride prescribed for treatment of candidiasis.,Airway burns
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Long-term treatment with rifabutin may have a reversible and previously undescribed side-effect on retinal function.,Retinal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To describe the clinical and electrophysiological findings in a young boy with decreased vision possibly due to retinal damage by rifabutin.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Retinal dysfunction and anterior segment deposits in a patient treated with rifabutin.,Corneal deposits
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We suggest that objective evaluation of retinal function with electrophysiological methods should be performed in patients with visual disturbance during treatment with rifabutin.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case is presented of a patient who experienced benzodiazepine withdrawal symptoms on discontinuation of nefazodone, an antidepressant that inhibits the cytochrome P450 3A4 isoenzyme.",Drug Withdrawal syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of SIADH induced by mizoribin administration.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"ADH hypersecretion in relation to plasma osmolality was reversed by mizoribin withdrawal, suggesting that bredinin might adversely induce SIADH.",Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In summary, we report herein the first case of SIADH believed to be an adverse effect of mizoribin, which may therefore needed to be added to the list of drugs which can induce SIADH.",Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a 74-year-old man with rheumatoid arthritis (RA) who developed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) 1.5 months after commencement of mizoribin prescription when his arthritis was improved.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The disease-modifying drugs he was taking, cyclosporin and methotrexate, were stopped, and the lymphoma resolved spontaneously without the use of chemotherapy.",Lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute onset of nephrotic syndrome during interferon-alpha retreatment for chronic active hepatitis C.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We herein report this rare case of acute onset of nephrotic syndrome during interferon-alpha retreatment.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 21-year-old man with Tourette's syndrome, pedophilia, Asperger's syndrome, and multiple sclerosis experienced seizures after receiving therapy with interferon beta-1a.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine.",Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 68-year-old female patient with advanced ovarian carcinoma collapsed whilst receiving a carboplatin and cyclophosphamide infusion.,Circulatory collapse
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carboplatin hypersensitivity presenting as coronary vasospasm - a case report.,Arteriospasm coronary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypersensitivity to carboplatin is a rare but real complication of therapy and should be considered in patients presenting with hyperacute changes on ECG whilst receiving carboplatin therapy.,Electrocardiogram abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 60-year-old white man with chronic bronchitis was noted to develop acute respiratory failure and metabolic acidosis four days after being started on methazolamide (Neptazane) for an ophthalmologic problem.,Acute Respiratory failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Capecitabine was discontinued and the allergic reactions resolved after the woman took diphenhydramine for 1 week.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The use of fluorouracil treatment with careful monitoring can be considered in a patient with mild allergic reactions to capecitabine.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fluorouracil for allergic reactions to capecitabine.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It was postulated that the allergic reaction was most likely caused by capecitabine or the intermediate metabolites based on the immediate reappearance of symptoms from the rechallenge, pharmacokinetic data, and well-tolerance of fluorouracil.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the safe use of fluorouracil in a patient with breast cancer who had allergic reactions to capecitabine.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"She developed a generalized rash and itching, sore throat, and dizziness approximately 4 hours after the first dose of capecitabine.",Dizziness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After five and six weeks of continuous oral administration of methylprednisolone, the boys developed steroid diabetes.",Steroid Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reduction of methylprednisolone dosage rather than insulin therapy resulted in better control of glycemia.,Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Contrary to previous recommendations, our experience cautions against the further use of high-dose cytarabine in patients who develop PPE, and is a timely reminder of the potential toxicity of this agent, which is now increasingly being used as first-line treatment in the management of haematologic malignancies.",Palmar-plantar erythrodysaesthesia syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It has been suggested that PPE caused by cytarabine does not recur with subsequent cytarabine re-challenge.,Palmar-plantar erythrodysaesthesia syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Recurrent palmar-plantar erythrodysaesthesia following high-dose cytarabine treatment for acute lymphoblastic leukemia.,Palmar-plantar erythrodysaesthesia syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a patient with recurrent, increasingly severe episodes of PPE, ultimately complicated by a severe bullous eruption, following successive cycles of high-dose cytarabine for the treatment of acute lymphoblastic leukaemia.",Dermatitis bullous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atypical endometriosis may act as a precancerous lesion in the process of tamoxifen-induced malignant transformation of endometriosis.,Endometriosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,BACKGROUND: Ovarian cancer arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy is rare.,Ovarian cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Tamoxifen may cause malignant transformation of endometriosis through atypical endometriosis even in the postmenopausal state.,Endometriosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ovarian endometrioid adenocarcinoma arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy for breast cancer: a case report.,Ovarian endometrioid carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Clinical, spectroscopic, and imaging abnormalities resolved with discontinuation of metronidazole.",Investigation abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Proton MRS examination demonstrated a persistent lactate elevation during metronidazole treatment.,Lactic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,After nine previous uncomplicated cycles she developed severe anaphylaxis to cisplatin.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylaxis to cisplatin following nine previous uncomplicated cycles.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylaxis to cisplatin is an infrequent life-threatening complication which may occur even in patients who have received prior treatment with cisplatin.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although isradipine has been associated with hepatocellular injury, there are no reports of fulminant liver failure with this agent, and our patient had been treated for >2 years without signs of toxicity.",Hepatocellular injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A second possibility is an interaction between clarithromycin and isradipine, potentially increasing the hepatic toxicity of isradipine.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE SUMMARY: A 58-year-old white woman developed fulminant liver failure while being treated with the macrolide antibiotic clarithromycin for pneumonia.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Clarithromycin may be a cause of fulminant liver failure either alone or by inhibiting the metabolism of other drugs.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fulminant liver failure associated with clarithromycin.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a patient developing fulminant liver failure while being treated with clarithromycin for pneumonia.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The most likely cause of liver failure in this patient was, therefore, clarithromycin, which undergoes hepatic metabolism and has been reported to cause fulminant hepatic failure.",Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A paradoxical ocular effect of brimonidine.,Ocular vascular disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Under certain circumstances topical brimonidine can cause paradoxical raised IOP necessitating vigilance in follow-up of patients on topical brimonidine.,Ocular hyperaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: We report an unusual paradoxical effect of brimonidine.,Paradoxical drug reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: Brimonidine was observed to cause IOP elevation, confirmed on rechallenge, scoring 8 (strong probability) on an adverse drug reaction probability score.",Intraocular pressure increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although gabapentin withdrawal has been previously reported and usually consists of anxiety, diaphoresis, and palpitations, this is the first reported patient with generalized seizures and status epilepticus secondary to gabapentin withdrawal.",Anxiety
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gabapentin withdrawal presenting as status epilepticus.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although visual hallucinations have not been reported as an adverse effect of this agent, we describe three patients who experienced complex visual hallucinations and altered mental status after zonisamide treatment was begun or its dosage increased.","Hallucination, visual"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Visual hallucinations associated with zonisamide.,Visual Hallucination
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Doxycycline-induced hypoglycemia in a nondiabetic young man.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of doxycycline-induced hypoglycemia in a young nondiabetic man.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"For patients who suffer from osteogenic sarcoma and have anaphylactic reactions to MTX, this desensitization protocol will allow these patients to continue with needed therapeutic or palliative chemotherapy.",Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"He had an immediate hypersensitivity reaction during the initiation of the MTX infusion with diffuse urticaria, facial swelling, cough, and chest tightness.",Chest discomfort
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,He was later skin tested to confirm allergy to MTX.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Successful desensitization to high-dose methotrexate after systemic anaphylaxis.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The successful development and implementation of this protocol will have impact on patients who have anaphylactic reactions to MTX but require this medication for specific diseases.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report a case of Balint syndrome with irreversible posterior leukoencephalopathy on MRI following intrathecal methotrexate and cytarabine.,Balint syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a unique case of GTBM in a patient with myeloma following treatment with Melphalan.,Plasma cell myeloma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patients with lymphoblastic lymphoma who had treatment with L-asparaginase and steroid are predisposed to the development of cortical venous thrombosis and may have this syndrome in addition to a dural puncture headache.,Cerebral venous Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interstitial pneumonitis associated with sirolimus: a dilemma for lung transplantation.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Rapamycin/sirolimus-induced pneumonitis has been described previously in renal transplant recipients, and this report describes a stable heart-lung transplant recipient who developed a pulmonary infiltrate that reversed after ceasing SR therapy.",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 16-year-old boy developed fever, generalized rigidity, leukocytosis, and increased serum transaminase and creatine kinase levels while receiving treatment with olanzapine and lithium.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Concomitant administration of lithium with olanzapine may place patients at risk for NMS.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neuroleptic malignant syndrome in an adolescent receiving olanzapine-lithium combination therapy.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Both 6-MP and AZA are widely used and are known to cause hepatotoxicity in a proportion of patients.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity associated with 6-thioguanine therapy for Crohn's disease.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case highlights the need to monitor liver enzymes in patients treated with 6-TG and identifies the need for additional research focused on the mechanism of thiopurine-induced hepatic injury.,Drug-induced Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We believe the temporal association of the abnormal liver enzymes in this patient, in the absence of other offending agents, argues strongly in favor of 6-TG as a cause of liver enzyme abnormalities.",Liver function test abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of significant elevation of serum transaminases in a patient treated with 6-TG for a flare of Crohn's disease.,Transaminases increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Early peritoneal dialysis has not previously been reported for lisinopril induced multiorgan failure.,Multiple organ dysfunction syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We observed transient panhypogammaglobulinaemia in a patient with neuropsychiatric SLE after treatment with prednisolone and cyclophosphamide.,Hypogammaglobulinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fulminant hepatic failure developed in a 24-year-old black woman who had been treated with propylthiouracil and propranolol for hyperthyroidism.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fulminant hepatitis and lymphocyte sensitization due to propylthiouracil.,Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These observations indicate that submassive hepatic necrosis may result from treatment with propylthiouracil and are consistent with the notion that sensitization mechanisms may be responsible for the hepatic injury induced by this drug.,Drug-induced Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The diagnosis of hypothermia was delayed until it was apparent for several days but resolved with the discontinuation of risperidone and continuation of clozapine.,Hypothermia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This is a case report of subtle, mild hypothermia in a 54-year old female patient receiving risperidone for schizophrenia.",Hypothermia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Akathisia is a relatively rare side effect with the newer atypical antipsychotic agents, particularly clozapine, and is easily misdiagnosed in children.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clozapine-induced akathisia in children with schizophrenia.,Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two cases of childhood-onset schizophrenia associated with clozapine-induced akathisia responsive to beta-blocker treatment are described.,Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,After reviewing the literature we suggest the CPM was a complication of lithium toxicity which affected the lateral geniculate nucleus which produced blindness.,Blindness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Central pontine myelinolysis manifested by temporary blindness: a possible complication of lithium toxicity.,Osmotic demyelination syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Antithyroid treatment with propylthiouracil (PTU) resulted in elevated hepatic enzymes and after the 12th week of pregnancy treatment was changed to carbimazole (CBZ).,Hepatic enzyme increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Successful treatment with carbimazole of a hyperthyroid pregnancy with hepatic impairment after propylthiouracil administration: a case report.,Hepatic function abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interferon-alpha (IFN-alpha) may precipitate or exacerbate the occurrence of MPGN.,Hepatic function abnormalImmune-complex membranoproliferative glomerulonephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Minimal change disease in a patient receiving IFN-alpha therapy for chronic hepatitis C virus infection.,Glomerulonephritis minimal lesion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 58-yr-old male patient with essential thrombocythaemia (ET) developed chronic myeloid leukaemia (CML) after continuous uneventful treatment with hydroxyurea for 18 yr.,Chronic myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Emergence of Philadelphia positive chronic myeloid leukaemia during treatment with hydroxyurea for Philadelphia negative essential thrombocythaemia.,Philadelphia positive Chronic myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There are no previous reports in the literature about the emergence of CML during treatment with hydroxyurea.,Chronic myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 72-year-old woman with a history of thyrotoxicosis presented with sore throat and fever two weeks after starting carbimazole.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Treatment of carbimazole-induced agranulocytosis and sepsis with granulocyte colony stimulating factor.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present the management of agranulocytosis and neutropenic sepsis secondary to carbimazole with recombinant human granulocyte colony stimulating factor (G-CSF).,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Comeoscleral perforation after pterygium excision and intraoperative mitomycin C.,Corneal perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To the best of our knowledge, corneoscleral melting in the first postoperative week after a single intraoperative application of mitomycin C has not been reported.",Corneal perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 71-year-old man, who had a history of a previous bullous drug reaction to a sulfonamide, began receiving an ophthalmic preparation that contained sulfacetamide sodium.",Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient received only the ophthalmic sulfonamide, and it was used for one day, but he developed Stevens-Johnson syndrome.",Stevens-Johnson syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The sulfonamides are the best verified drug-trigger for erythema multiforme and Stevens-Johnson syndrome.,Erythema multiforme
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Based on these findings, the patient was diagnosed with diabetes insipidus secondary to lithium therapy and was treated successfully with amiloride.",Diabetes insipidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Treatment of lithium-induced diabetes insipidus with amiloride.,Diabetes insipidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Systemic capillary leak syndrome after granulocyte colony-stimulating factor (G-CSF).,Granulocyte-colony stimulating factor level increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present two cases in which both patients suffered with CLS, which we believe was caused following administration of granulocyte colony-stimulating factor, to our knowledge not described in the intensive care patient previously.",Kawasaki's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"FK506, which began to be administered 12 days earlier, rose to a level of 44 ng/mL (normal range, 10-20 ng/mL) 1 day before neurologic abnormalities began.",Immune-mediated neurological disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rapid identification of speech loss linked to FK506 may be important because reduction or cessation of the drug may be associated with reverse of speech loss.,Aphasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Tacrolimus (FK506), an immunosuppressant, has been associated with mutism in adults after liver transplant.",Mutism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tacrolimus (FK506)-induced mutism after liver transplant.,Mutism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin oedema?",OOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Soon after introduction of insulin therapy, she developed severe anasarca, including marked peripheral oedema, ascites and pleural effusion.",Ascites
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The induced hyperglycaemia could not be controlled sufficiently, despite a high dose of insulin (> 110 units/day), suggesting the existence of insulin insensitivity and hyperinsulinaemia.",Hyperinsulinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intrathecal methotrexate-induced acute cerebellar syndrome.,Cerebellar syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient who developed acute cerebellar syndrome after prophylactic intrathecal methotrexate administration and recovered spontaneously.,Cerebellar syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Angioimmunoblastic lymphadenopathy with dysproteinemia following doxycycline administration.,Angioimmunoblastic T-cell lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of AILD in an 80-year-old male who presented with a generalized pruritic maculopapular eruption and fever following doxycycline administration.,Angioimmunoblastic T-cell lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylaxis from isoniazid is a possible side effect to this commonly prescribed antibiotic.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Isoniazid-induced anaphylaxis.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case is reported in which severe hypocalcemia, with a low plasma parathyroid hormone (PTH) concentration, resulted from the therapeutic use of magnesium sulfate for toxemia of pregnancy.",Hypoparathyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carbamazepine-related hyponatremia following cardiopulmonary bypass.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We discuss the association between carbamazepine and hyponatremia and the causes of hyponatremia after cardiopulmonary bypass.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After 5-ASA was discontinued, the polyneuropathy symptoms recovered gradually.",PolyNeuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sensorimotor polyneuropathy with 5-aminosalicylic acid: a case report.,Peripheral sensorimotor Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This clinical course suggests that the sensorimotor polyneuropathy may have been caused by 5-ASA.,Peripheral sensorimotor Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When SASP was changed to 5-aminosalicylic acid (5-ASA), his skin eruptions were resolved, however, he developed weakness and atrophy in his right arm as well as progressive worsening of the dysesthesia in his legs and gait disturbance.",Atrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disseminated cellulitic cryptococcosis in the setting of prednisone monotherapy for pemphigus vulgaris.,Cryptococcosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In both cases, high fever, skin rash, liver dysfunction and atypical lymphocytosis developed 3 weeks after initiating treatment with SASP.",Lymphocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Slow acetylator genotypes as a possible risk factor for infectious mononucleosis-like syndrome induced by salazosulfapyridine.,Infectious mononucleosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two patients with infectious mononucleosis-like syndrome induced by salazosulfapyridine (SASP).,Infectious mononucleosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 45-year-old woman with steroid-dependent Crohn's colitis, successfully managed with maintenance infliximab infusions and methotrexate, developed a lupus-like syndrome eight months after her initial infusion.",Lupus-like syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A lupus-like syndrome associated with infliximab therapy.,Lupus-like syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Infliximab therapy may cause a lupus-like syndrome that is reversible upon discontinuing this agent.,Lupus-like syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report in detail an unusual adverse reaction to infliximab therapy, a drug-induced lupus-like clinical syndrome.",Lupus-like syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Chronic myelogenous leukemia (CML), hepatitis C, and interferon alpha (IFNalpha) have all been associated with renal dysfunction.",Renal tubular dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Despite the underlying hepatitis C, this case represents renal abnormalities consistent with IFNalpha therapy for CML.",Renal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interferon-alpha-induced focal segmental glomerulosclerosis in chronic myelogenous leukemia: a case report and review of the literature.,Focal segmental glomerulosclerosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The renal biopsy showed focal segmental glomerulosclerosis, which has only been previously reported in two cases of CML treated with IFNalpha.",Focal segmental glomerulosclerosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe autoimmune hemolytic anemia following rituximab therapy in a patient with a lymphoproliferative disorder.,Autoimmune haemolytic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The pathophysiological mechanisms remain unknown, although the drug could act through massive cytokines liberation after destruction of CD20 positive cells by rituximab.",B-cell depletion therapy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the first case, to our knowledge, of rituximab-related autoimmune hemolytic anemia.",Autoimmune haemolytic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Early-onset acute transverse myelitis following hepatitis B vaccination and respiratory infection: case report.,Myelitis transverse
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this paper, we report a case of 3 years-old boy who developed acute onset tetraparesia following a viral respiratory infecction and hepatitis B vaccination.",Quadriparesis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although it would be expected that, like other type IA toxicities, diphenhydramine-induced cardiotoxicity could be responsive to hypertonic sodium bicarbonate, this finding is largely unappreciated.",Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diphenhydramine-induced wide complex dysrhythmia responds to treatment with sodium bicarbonate.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, because diphenhydramine also exhibits type IA sodium channel blockade, cardiac toxicity is also possible.",Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe 3 cases of diphenhydramine-induced cardiac toxicity that were responsive to bicarbonate.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient with extranodal non-Hodgkin lymphoma who developed systemic candidiasis after treatment with a cyclophosphamide-based chemotherapy regimen.,Systemic candida
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Stevens-Johnson syndrome in a boy with nephrotic syndrome during prednisolone therapy.,Stevens-Johnson syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of SJS in a 14-year-old male with nephrotic syndrome, who was treated with oral prednisolone for 6 weeks.",SJS-Toxic epidermal necrolysis overlap
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 25-year-old man with a history of mid-borderline (BB) Hansen's disease developing a reversal reaction after starting dapsone and rifampin therapy is presented.,Leprosy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, in order to avoid neuropathic side effects, patients under thalidomide therapy should be monitored every 6 months with nerve conduction studies while taking the drug.",Neuropathy peripheral peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After a two-month interruption of interferon administration, natural interferon alpha was given but followed by another episode of the same neurological manifestations.",Diabetic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Case 1, a 62-year-old woman, developed bilateral optic neuritis with decreased sensation of vibration and increased deep tendon reflex in the lower extremities after a seven-month use of recombinant interferon alpha-2a for chronic active hepatitis C.",Optic neuritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Case 2, a 29-year-old woman, developed bilateral optic neuritis combined with numbness of the lower extremities as well as bowel and bladder dysfunction after a 22-month use of recombinant interferon alpha-2b for chronic myelogenous leukemia.",Optic neuritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Optic neuritis in combination with other neurological signs, simulating multiple sclerosis, should be included in the list of adverse effects of recombinant and natural interferon alpha administration.",Neurological symptom
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Multiple sclerosis-like disease secondary to alpha interferon.,Autoimmune demyelinating disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To describe bilateral optic neuritis that occurred as an adverse effect of recombinant and natural interferon alpha administration.,Optic neuritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute abdomen due to endometriosis in a premenopausal woman taking tamoxifen.,Acute abdomen
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a premenopausal woman who, while having tamoxifen due to a diagnosis of in situ ductal carcinoma, developed endometriosis requiring surgery.",Endometriosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case report of fatal dapsone-induced agranulocytosis in an Indian mid-borderline leprosy patient.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fatal agranulocytosis in an Indian male receiving 100mg of dapsone daily, hospitalized for mid-borderline leprosy in type I reaction with triple nerve paralysis is reported.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Various case reports concerning dapsone-induced agranulocytosis are reviewed.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Massive pulmonary embolism due to late-onset heparin-induced thrombocytopenia following coronary artery bypass graft surgery: successful treatment with lepirudin.,Pulmonary embolism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Most cardiac surgical patients have had previous exposure to heparin for diagnostic or therapeutic interventions and hence have an increased susceptibility to developing heparin-induced thrombocytopenia (HIT) postoperatively.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute psychosis associated with levetiracetam.,Acute Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A twelve year-old-girl with idiopathic partial epilepsy with secondary generalization, developed acute psychosis 10 days after the administration of levetiracetam.",Acute Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The psychotic behavior resolved completely soon after the discontinuation of levetiracetam.,Psychotic behaviour
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASES: ""A"" was an 8-year-old boy with attention deficit and chronic tic disorder who developed obsessive-compulsive symptoms within 2 weeks of starting risperidone.",Obsessive-compulsive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Obsessive-compulsive symptoms suddenly emerged 10 days after starting risperidone and resolved within 3 days of discontinuation.,Obsessive-compulsive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Risperidone-induced obsessive-compulsive symptoms in two children.,Obsessive-compulsive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Proliferation of abnormal bone marrow histiocytes, an undesired effect of granulocyte macrophage-colony-stimulating factor therapy in a patient with Hurler's syndrome undergoing bone marrow transplantation.",Histiocytic sarComa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Possible heart failure exacerbation associated with rosiglitazone: case report and literature review.,Cardiac failure congestive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Enoxaparin-induced generalized exanthem.,Acute generalised exanthematous pustulosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Only one case of a generalized maculopapular rash with enoxaparin has been reported in Europe.,Rash maculo-papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first case reported in the English literature of a generalized exanthem due to subcutaneous injection of enoxaparin.",Acute generalised exanthematous pustulosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Behavioral side effects associated with clonazepam may include agitation, aggression, hyperactivity, irritability, property destruction, and temper tantrums.",Aggression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This report describes an individual with mental retardation who experienced behavioral exacerbation associated with clonazepam prescribed at 2 mg/day (0.02 mg/kg/day) to treat aggression, self-injurious behavior, property destruction, and screaming, which was measured with a 15-minute partial interval recording measurement method.",Neuropsychological symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cefuroxime-induced immune hemolysis.,Warm autoimmune haemolytic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of IHA associated with cefuroxime administration.,Autoimmune haemolytic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After 39 hours on argatroban, the infusion was stopped when minor bleeding was observed with a concurrent activated partial thromboplastin time (aPTT) of 100 seconds.",Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Argatroban for heparin-induced thrombocytopenia in hepato-renal failure and CVVHD.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Argatroban is hepatically cleared and may be the preferred direct thrombin inhibitor in the presence of significant renal impairment, but conversely has prolonged effects in hepatic failure.",Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of significant hepatic and renal failure with the use of argatroban in a patient with heparin-induced thrombocytopenia (HIT) requiring continuous veno-veno hemodialysis (CVVHD).,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Schneiderian first-rank symptoms associated with fluvoxamine treatment: a case report.,"Hallucination, auditory"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient, a 28-year-old man suffering from panic disorder, developed several first-rank symptoms during fluvoxamine administration.","Hallucination, auditory"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This communication describes a patient who developed Schneiderian first-rank symptoms in the course of treatment with fluvoxamine.,"Hallucination, auditory"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This finding suggests that fluvoxamine can precipitate Schneiderian first-rank symptoms in some susceptible patients.,"Hallucination, auditory"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a surprising case of a woman schizophrenic patient treated with clozapine suffering from EPS.,Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hyperpigmentation during interferon-alpha therapy for chronic hepatitis C virus infection.,HyperPigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These skin lesions may be induced or worsened during antiviral therapy with interferon-alpha (IFN).,Yaws of skin
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe two dark-skinned patients who developed hyperpigmented skin and tongue lesions during combination therapy with IFN and ribavirin.,Skin hyperPigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is concluded that simultaneous administration of ciprofloxacin and tazobactam/piperacillin may cause marked thrombocytosis.,Thrombocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since the thrombocyte count started to increase immediately after initiation and dropped immediately after discontinuation of ciprofloxacin and tazobactam/piperacillin and all other drugs were discontinued already before or were started after the nadir of the thrombocyte count, these two antibiotics were regarded causative.",Thrombocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombocytosis under ciprofloxacin and tazobactam/piperacillin.,Thrombocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylaxis after the injection of chymopapain occurs in about 1% of such cases.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Both patients suddenly became hypotensive after injection of chymopapain into a disk.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lethargy in a newborn: lithium toxicity or lab error?,Lethargy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The newborn manifested a four day course of lethargy with unexplained high lithium levels in the adult toxic range.,Lethargy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carbamazepine-induced systemic lupus erythematosus-like disease.,Lupus-like syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The cases of CBZ-induced SLE reported in the literature were reviewed.,Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After four months, while receiving RH, he developed painful bilateral gynaecomastia.",GynaeComastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gynaecomastia is a rarely reported adverse drug reaction due to isoniazid therapy.,GynaeComastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Isoniazid associated, painful, bilateral gynaecomastia.",GynaeComastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient suffering from heparin-associated thrombocytopenia (HAT), recurrent arteriothromboses, and acute renal failure after treatment with standard heparin is described.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"By means of the in vitro heparin-induced platelet activation (HIPA) assay it was shown that standard heparin and the LMW heparins Fragmin and Fraxiparin (Sanofi Labaz, Munich, FRG), as well as the enoxaparine Clexane (Nattermann, Cologne, FRG), all induced platelet activation with the patient's serum.",Heparin-induced thrombocytopenia test
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Heparin-associated thrombocytopenia: successful therapy with the heparinoid Org 10172 in a patient showing cross-reaction to LMW heparins.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hemodynamic collapse following labetalol administration in preeclampsia.,Shock
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient with Parkinson's disease, initially treated with bromocriptine and subsequently with cabergoline, developed progressive pleuropulmonary abnormalities during the latter therapy.",Lung disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pleuropulmonary changes during treatment of Parkinson's disease with a long-acting ergot derivative, cabergoline.",Lung disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thus cabergoline may cause similar pleuropulmonary abnormalities to bromocriptine.,Lung disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute myopathy with selective degeneration of myosin filaments following status asthmaticus treated with methylprednisolone and vecuronium.,Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Flaccid quadriparesis was noted after discontinuation of vecuronium.,Quadriparesis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This entity is probably related to a combination of high doses of corticosteroids, vecuronium administration and metabolic abnormalities associated with respiratory failure.",Respiratory failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient with ulcerative colitis developed skin pigmentation and diffuse pulmonary shadowing without respiratory symptomatology, while taking sulfasalazine.",Lung infiltration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary infiltrates and skin pigmentation associated with sulfasalazine.,Lung infiltration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Sulfasalazine-induced lung disorder is an extremely rare entity which must be considered in all ulcerative colitis patients while on sulfasalazine therapy, despite the absence of pulmonary symptomatology.",Lung disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although an association between exposure to bleomycin and the development of scleroderma has been suspected, few cases are reported.",Scleroderma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Our series of 3 patients supports a causal connection between bleomycin and scleroderma.,Scleroderma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Scleroderma in association with the use of bleomycin: a report of 3 cases.,Scleroderma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the development of cutaneous scleroderma in 3 patients coincident with the use of bleomycin in low cumulative doses of less than 100 U.,Scleroderma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient presented with dilated cardiomyopathy after many years of overusing an adrenaline inhaler.,Dilated Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dilated cardiomyopathy associated with chronic overuse of an adrenaline inhaler.,Dilated Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 21-year-old woman suffering from bipolar affective disorder developed systemic lupus erythematosus (SLE) with characteristic laboratory findings, 18 months after starting carbamazepine maintenance treatment.",Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although both the spontaneous occurrence of SLE and the psychosis as a sign of CNS involvement of SLE cannot be excluded, SLE could be considered as an adverse effect of carbamazepine.",Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carbamazepine-induced systemic lupus erythematosus.,Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,SLE receded after withdrawal of carbamazepine and treatment with anti-inflammatory drugs.,Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of acne fulminans occurring during treatment with 13-cis-retinoic acid for cystic acne.,Acne fulminans
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma.,Coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Valproic acid induced coma is presented in an adult patient without a history of metabolic disease.,Coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Asterixis induced by carbamazepine therapy.,Asterixis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this report we present four patients treated with a combination of different psychotropic drugs, in whom asterixis was triggered either by adding carbamazepine (CBZ) to a treatment regimen, or by increasing its dosage.",Asterixis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We consider asterixis to be an easily overlooked sign of neurotoxicity, which may occur even at low or moderate dosage levels, if certain drugs as lithium or clozapine are used in combination with CBZ.",Asterixis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Encephalopathy and seizures induced by intravesical alum irrigations.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hemorrhagic cystitis is a significant toxic effect of cyclophosphamide therapy.,Cystitis haemorrhagic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Seizure with hyponatremia in a child prescribed desmopressin for nocturnal enuresis.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of hyponatremia associated with a grand mal seizure in a 28 month-old child after intra-nasal desmopressin administration for high fluid intake with nocturnal enuresis.,Generalised tonic-clonic seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case report describes a 38-year-old male in whom SIADH was strongly suspected secondary to Tegretol therapy to control a seizure disorder.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Gestational diabetes was no less severe (degree of hyperglycaemia, need for insulin therapy) when associated with norethisterone.",Gestational Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, follow-up revealed that gestational diabetes when associated with norethisterone had a lesser risk of emerging diabetes mellitus and impaired glucose tolerance.",Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In a single practice during the 21 years 1971-1991, the incidence of gestational diabetes in pregnancies in which norethisterone was prescribed was 32.4% (22 of 69) in comparison with 7.1% in pregnancies in which the women did not take norethisterone (137 of 1,684) (p < 0.001).",Gestational Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Masculinization of a female fetus occurred in 5 of 39 (12.8%) exposed to norethisterone; all were cases of clitoral hypertrophy not requiring surgical treatment.,Hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Norethisterone in these 69 pregnancies accounted for 33.3% (5 of 15) cases of clitoral hypertrophy diagnosed in 100,756 consecutive births.",Hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An adverse reaction to IFN was strongly suspected as the cause of CHF.,Cardiac failure congestive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Multiple myeloma complicated by congestive heart failure following first administration of recombinant alpha-interferon.,Cardiac failure congestive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Sixteen hours after the first administration of IFN, IFN was suspended by the symptoms of congestive heart failure (CHF).",Cardiac failure congestive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neutrophilic eccrine hidradenitis mimicking cutaneous vasculitis in a lupus patient: a complication of cyclophosphamide.,Hidradenitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of NEH masquerading as cutaneous vasculitis in a woman receiving cyclophosphamide for lupus nephritis.,Hidradenitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Generalised cutaneous rash associated with ganciclovir therapy has rarely been reported in literature.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Skin rash and splinter hemorrhages from ganciclovir.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Can roxithromycin and betamethasone induce acute pancreatitis? A case report.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE REPORT: We report the case of a 58 year old patient who, after 2 days of treatment with roxithromycin and betamethasone, manifested acute pancreatitis.",Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Renal tubular acidosis secondary to FK506 in living donor liver transplantation: a case report.,Renal tubular acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RTA is one type of nephrotoxicity induced by FK506, and it is reversible in mild cases when appropriately treated.",Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Surgeons and physicians should therefore be aware of the potential for RTA to occur with FK506 after any organ transplantation.,Renal tubular acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The mechanism of RTA induced by FK506 has not yet been clearly elucidated.,Renal tubular acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The treatment for acidosis and hyperkalaemia should be started as soon as RTA is diagnosed, and the dosage of FK506 should also be reduced if possible.",Renal tubular acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of RTA secondary to FK506 administration in liver transplantation.,Renal tubular acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 74-year-old patient with idiopathic Parkinson's disease was evaluated for unintended sleep episodes that occurred after long-term treatment with 400 mg/day of L-dopa.,Somnolence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,L-DOPA-induced excessive daytime sleepiness in PD: a placebo-controlled case with MSLT assessment.,Somnolence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors' results suggest that L-dopa may cause daytime somnolence in some patients with Parkinson's disease.,Somnolence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neurotoxicity of intrathecal methotrexate: MR imaging findings.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We attribute the clinical and radiographic findings to cytotoxic edema secondary to intrathecal methotrexate.,Cytotoxic oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of intrathecal methotrexate neurotoxicity manifesting as left arm weakness and aphasia.,Aphasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this article lithium is not discussed, although there are a number of concerns about lithium's potential teratogenicity, and it has been implicated in Epstein's anomaly, a congenital heart defect among infants born to women taking lithium; as with other medications, however, the data have specific limitations.",Ebstein's anomaly
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a case of a 20-year-old woman who ingested 900 mg of glyburide causing refractory hypoglycemia resistant to treatment with intravenous dextrose, glucagon, and diazoxide.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ocular ethambutol toxicity.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The most commonly recognized toxic effect of ethambutol is optic neuropathy, which generally is considered uncommon and reversible in medical literature.",Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case and a review of the literature show the severe and unpredictable nature of ethambutol toxicity and its potential for irreversible vision loss despite careful ophthalmologic monitoring.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a 43-year-old man who developed signs and symptoms of bilateral optic neuropathy during treatment with ethambutol.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The case history and toxicological findings of an infant fatality involving pseudoephedrine, brompheniramine, and dextromethorphan are presented.",Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Early overanticoagulation with acenocoumarol due to a genetic polymorphism of cytochrome P450 CYP2C9.,Coagulation time prolonged
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a young healthy woman who presented an early overanticoagulation when receiving acenocoumarol for a first thromboembolic episode.,Coagulation time prolonged
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Colchicine-induced myopathy in a teenager with familial Mediterranean fever.,Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Colchicine-induced myopathy should be excluded in patients with FMF who present with generalized muscle weakness.,Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: Colchicine, the most important drug in treatment of FMF, can cause myopathy in patients with impaired renal and hepatic function.",Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In our patient, an objective causality scale showed that therapeutic doses of colchicine for FMF were the definite cause of myopathy, even though his renal and hepatic function were normal.",Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of colchicine-induced myopathy in a teenager with familial Mediterranean fever (FMF).,Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Angioedema and dysphagia caused by contact allergy to inhaled budesonide.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a 43-year-old woman who developed sore throat, swelling of the lips and oral cavity and dysphagia, 2 weeks after the use of budesonide spray (Budefat) for treatment of bronchial asthma.",Dysphagia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Infectious toxicity of dexamethasone during all remission-induction chemotherapy: report of two cases and literature review.,Infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the infectious toxicities experienced by the first two patients in our institution treated with dexamethasone (10 mg/m(2)/day for 4 weeks with gradual tapering) during induction according to the dexamethasone arm of BFM 2000 and review the relevant literature that suggests an increased risk of infectious complications with dexamethasone.,Infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient who developed NEH on three separate occasions provoked by two different chemotherapeutic agents--cytarabine and mitoxantrone.,Hidradenitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A diagnosis of infliximab-induced lupus was made and the drug treatment was withdrawn.,Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Infliximab-induced lupus in Crohn's disease: a case report.,Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This is the first case, to our knowledge, of onset of prolonged infliximab-induced lupus.",Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Treatment with infliximab is known to produce an increase of autoantibodies (antinuclear antibodies, anti-double-stranded DNA), but not clinical disease.",Double stranded DNA antibody
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe Raynaud's phenomenon with yohimbine therapy for erectile dysfunction.,Raynaud's phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a patient with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia) who paradoxically experienced worsening of Raynaud's phenomenon when using yohimbine for ED.",Raynaud's phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After initiation of topical vitamin D3 ointment (20 micro g/g of tacalcitol) 10 g/day for the skin lesions, both the serum level of calcium and urinary excretion of calcium increased gradually.",Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Iatrogenic hypercalcemia due to vitamin D3 ointment (1,24(OH)2D3) combined with thiazide diuretics in a case of psoriasis.",Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The present case is the first report of hypercalcemia induced by vitamin D3 ointment and thiazide simultaneously.,Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We experienced a male patient with psoriasis and hypertension whose conditions were treated with tacalcitol ointment and thiazide, respectively, resulting in hypercalciuria and hypercalcemia.",Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,2-CdA typically causes a long-lasting state of immunodeficiency and the profound influence of this drug on the immune system has raised questions concerning the emergence of secondary neoplasms after its use.,Immunodeficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,2-Chloro-deoxyadenosine induces durable complete remission in Castleman's disease but may accelerate its transformation to non-Hodgkin's lymphoma.,Non-Hodgkin's lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Therefore, it is reasonable to conclude that: 1) 2-CdA can induce durable complete remission in MCD patients but unfortunately it cannot cure the disease; 2) the possibility that 2-CdA may accelerate the transformation of MCD to NHL cannot be ruled out.",Non-Hodgkin's lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since this amount of FAB was insufficient to bind all DGTX present in the serum, cardiac DGTX toxicity (total AV-block) persisted.",Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,All patients had taken phenytoin for variable time periods (range 16-80 days; mean: 40) and were on the medication when the skin lesions first appeared.,Yaws of skin
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Erythema multiforme associated with phenytoin and cranial radiation therapy: a report of three patients and review of the literature.,Erythema multiforme
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In conclusion, RSDS is a relevant osteoarticular complication in patients receiving either anticalcineurinic drug (CyA or tacrolimus), even under monotherapy or with a low steroid dose.",Complex regional pain syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reflex sympathetic dystrophy syndrome in renal transplanted patients under immunosuppression with tacrolimus.,Complex regional pain syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We now present four cases of RSDS in kidney transplant recipients treated with tacrolimus.,Complex regional pain syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Topiramate may be associated with ciliochoroidal effusion with forward displacement of the lens-iris diaphragm and anterior chamber shallowing, resulting in acute myopia and angle-closure glaucoma.",Acute myopia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mechanism of topiramate-induced acute-onset myopia and angle closure glaucoma.,Acute myopia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"METHODS: In an institutional practice setting, two women, aged 25 and 45, developed acute myopia after starting topiramate for epilepsy.",Acute myopia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Doxycycline-induced photo-onycholysis.,Photoonycholysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of photo-onycholysis in a patient treated with doxycycline for acne vulgaris.,Photoonycholysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A new type of minocycline-induced cutaneous hyperpigmentation.,Skin hyperPigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This fourth type of cutaneous minocycline hyperpigmentation may be a variant of Type I, but based on clinical, pathological and microanalytical differences, appears to be a new entity.",Skin hyperPigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three distinct types of minocycline-induced cutaneous pigmentation have been described.,Skin hyperPigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two patients with acne vulgaris with a fourth type of minocycline-induced cutaneous pigmentation.,Skin hyperPigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ciprofloxacin-induced toxic epidermal necrolysis in a patient with systemic lupus erythematosus.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report here a case of TEN after administration of ciprofloxacin.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 56-year-old Caucasian man who received concomitant chemotherapy and radiation for head and neck cancer developed fever concurrent with the administration of amifostine.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amifostine-induced fever: case report and review of the literature.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Patients receiving amifostine who develop only fever should be evaluated for an adverse drug reaction, as well as for sepsis and fevers of neutropenia, and it may be necessary to discontinue the drug.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first case report that demonstrates the occurrence of fever with low-dose amifostine therapy without the manifestation of accompanying rash or hypotension.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute interstitial nephritis due to pantoprazole.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After 5 weeks of therapy, she stopped taking pantoprazole due to general malaise.",Malaise
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: To describe what is believed, as of November 4, 2003, to be the first case published in the literature of acute interstitial nephritis (AIN) due to pantoprazole.",Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The Naranjo probability scale suggests a highly probable relationship between AIN and pantoprazole therapy in this patient.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There have been several reported cases of omeprazole-induced AIN.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It was highly suspected that finasteride was associated with the anterior subcapsular opacity on the lens, and the patient therefore discontinued use of finasteride.",Cataract subcapsular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propecia-associated bilateral cataract.,Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To the best of the authors' knowledge, this is the first reported case of Propecia-associated cataract.",Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Scleromyxedema in a patient with multiple sclerosis and monoclonal gammopathy on interferon beta-1a.,Lichen myxoOedematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE SUMMARY: Two children with attention deficit disorder treated with methylphenidate as a simple drug developed fixed drug eruption of the scrotum.,Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Fixed drug rash induced by methylphenidate is a possible but rare phenomenon.,Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fixed drug eruption of the scrotum due to methylphenidate.,Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report two cases of fixed drug eruption induced by methylphenidate.,Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate pneumonitis in nonsurgical treatment of ectopic pregnancy.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of pneumonitis following local administration of methotrexate for nonsurgical termination of an ectopic pregnancy.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: The risk/benefit ratio of warfarin therapy changes in the over 75s, when haemorrhagic side-effects become more common.",Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE REPORT: A woman of 80 years, on long-term warfarin therapy presented with an acute dissecting thoracic aortic aneurysm; on investigation the only precipitating factor found was an international normalised ratio of 4.8.",Aortic dissection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Warfarin-associated thoracic aortic dissection in an elderly woman.,Aortic dissection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cutaneous vasculitis secondary to ramipril.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Here we report ramipril-induced cutaneous vasculitis in a patient who required steroid therapy to control it.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ramipril-induced cutaneous vasculitis is particularly rare and our case was atypical because the patient had tolerated lisinopril before.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: This is, to our knowledge, the first report of severe myelopathy following accidental intrathecal administration of doxorubicin.",Myelopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neurological improvement and rehabilitation potential following toxic myelopathy due to intrathecal injection of doxorubicin.,Myelopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Evidence of neurological improvement and rehabilitation potential after severe myelopathy due to intrathecal injection of doxorubicin.,Myelopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,STUDY DESIGN: Case report of a 31-year-old woman who presented with toxic myelopathy due to intrathecal administration of doxorubicin.,Myelopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After infliximab treatment, additional sleep studies revealed an increase in the number of apneic events and SaO2 dips suggesting that TNFalpha plays an important role in the pathophysiology of sleep apnea.",Apnea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thus, clinical recognition of sleep disordered breathing should be taken into account when rheumatoid arthritis patients are to be treated with infliximab.",Sleep apnoea syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypernatraemia induced by sodium polystyrene sulphonate (Kayexalate) in two extremely low birth weight newborns.,Hypernatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe two ELBW infants affected by hyperkalaemia, treated with Kayexalate, who developed serious hypernatraemia, that has never been reported before in preterm infants.",Hypernatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bull's-eye maculopathy associated with quinacrine therapy for malaria.,Maculopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Low dosages of quinacrine used for malaria prophylaxis can be associated with a delayed, severe maculopathy indistinguishable from chloroquine maculopathy in certain patients.",Maculopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: A patient developed a bilaterally symmetric bull's-eye maculopathy 45 years after taking quinacrine for 18 months as prophylaxis against malaria.,Maculopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The clinical picture was identical to that of chloroquine and hydroxychloroquine maculopathy.,Maculopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Cerebral infarcts in a pediatric patient secondary to phenylpropanolamine, a recalled medication.",Cerebral infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Phenylpropanolamine (PPA) recently has been publicly implicated as a cause of stroke and other neurologic events.,Neuropathic arthropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient developed occipital infarcts and was found to have extremely elevated levels of PPA in his blood and dialysis fluid.,Neuropathic arthropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of stroke after PPA ingestion that occurred 4 months after the recall in an 8-year-old boy on chronic peritoneal dialysis.,Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Central nervous system effects secondary to ciprofloxacin treatment are uncommon and usually consist only of minor dizziness or mild headache, although rare occurrences of seizures and hallucinations have been reported.",Hallucination
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ciprofloxacin-induced psychosis.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DATA SYNTHESIS: A 49-year-old man developed symptoms of severe psychosis concomitant with ciprofloxacin (250 mg bid) treatment.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: To report a case of ciprofloxacin-induced psychosis and to discuss occurrence rates, risk factors, possible etiologies, preventive measures, and treatment courses for this adverse reaction.",Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Agranulocytosis induced by vancomycin in an ESRD patient on CAPD.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Agranulocytosis is a rare adverse effect associated with prolonged vancomycin therapy, and is potentially serious, especially in end stage renal disease (ESRD) patients.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a continuous ambulatory peritoneal dialysis (CAPD) patient that developed vancomycin-induced agranulocytosis during treatment for methicillin-resistant Staphylococcus aureus (MRSA)-associated external cuff infection and pneumonia.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is very likely that the dexamethasone used in the antiemetic drug regimen contributed to the development of osteonecrosis in these patients.,Osteonecrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Osteonecrosis is a serious side effect of antiemetic treatment with dexamethasone and this serious complication should be incorporated in the current guidelines.,Osteonecrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patients should be informed about the risk of osteonecrosis when taking dexamethasone as an antiemetic drug.,Osteonecrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of Peyronie's disease during long-term colchicine treatment.,Peyronie's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However here we reported two patients, presenting with PD during high dose colchicine treatment for familiar mediterranean fever (FMF).",Peyronie's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient developed cholestatic hepatitis while being treated with nitrofurantoin.,Hepatitis cholestatic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A second episode of jaundice followed the intravaginal administration of a mixture of furazolidone and nifuroxime.,Jaundice
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of unintentional overdose of oral pilocarpine tablets that resulted in bradycardia, mild hypotension, and muscarinic symptoms in a patient with Sjogren's syndrome.",Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although combinations of belladonna, ergotamine, and phenobarbital have been used for medical treatment of menopausal symptoms since the 1960s, this is the first known case report of its association with anticonvulsant hypersensitivity syndrome.",Drug reaction with Eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Anticonvulsant hypersensitivity syndrome associated with Bellamine S, a therapy for menopausal symptoms.",Drug reaction with Eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of a previously healthy, postmenopausal woman who developed anticonvulsant hypersensitivity syndrome while taking Bellamine S (belladonna alkaloids; ergotamine; phenobarbital) for hot flashes.",Drug reaction with Eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of heatstroke is reported in a 32-year-old man diagnosed with schizophrenia and on clozapine monotherapy.,Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Heat stroke in schizophrenia during clozapine treatment: rapid recognition and management.,Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gemcitabine-related radiation recall preferentially involves internal tissue and organs.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors also determined that their case of myositis developing in the rectus abdominus muscle of a patient with pancreatic adenocarcinoma was the manifestation of radiation recall, thereby bringing the number of patients who developed radiation recall to gemcitabine and were discussed in the current study to 13.",Myositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The literature search found 12 cases of radiation recall caused by gemcitabine.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The majority of radiation recall reactions attributed to gemcitabine are reported to affect internal tissue or organs.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cystoid macular edema in a low-risk patient after switching from latanoprost to bimatoprost.,Cystoid macular oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema.,Cystoid macular oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report a case of angiographically documented cystoid macula edema occurring after switching a pseudophakic patient from latanoprost to bimatoprost.,Cystoid macular oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An immediate hemolytic reaction induced by repeated administration of oxaliplatin.,Haemolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE REPORT: We report a patient who developed a DAT-positive hemolytic episode after a red cell (RBC) transfusion was delivered during the infusion of her 17th cycle of oxaliplatin.,Haemolytic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although neurotoxicity is a frequent complication of methotrexate therapy, fatal acute neurotoxicity is extremely uncommon, especially in adults.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Clinicians should be aware of the signs and symptoms of neurotoxicity during treatment, as well as predisposing factors that put patients receiving methotrexate at risk for neurotoxic effects.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal acute encephalomyelitis after a single dose of intrathecal methotrexate.,Acute disseminated encephalomyelitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The day after methotrexate administration, the patient complained of severe back pain and urinary retention.",Back pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This patient rapidly progressed from mild neurotoxicity to fatal encephalopathy after one dose of intrathecal methotrexate during his third cycle of chemotherapy.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a third case of a 6-week-old infant with Escherichia coli sepsis who received ampicillin and other antibiotics and subsequently developed TEN.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One patient developed large intramural esophageal hematoma as a complication of heparin therapy.,Oesophageal intramural haematoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Eosinophilic cystitis after bladder instillation with dimethyl sulfoxide.,Eosinophilic cystitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of an acute flare of eosinophilic cystitis in a 51-year-old woman after bladder instillation with dimethyl sulfoxide (DMSO) for presumed interstitial cystitis.,Eosinophilic cystitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute dystonia during pegylated interferon alpha therapy in a case with chronic hepatitis B infection.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this case report, we present clinical and laboratory findings of a case with chronic hepatitis B that developed acute dystonia soon after the first dose of pegylated interferon alpha.",Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Therapy with IFN-alpha may be associated with a number of neuropsychiatric symptoms, such as Parkinsonism, akathisia, seizure, and depressive disorders.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient developed restless legs symptoms paralleling the course of interferon-alpha (IFN alpha) therapy for chronic hepatitis C.,Restless legs syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Restless legs syndrome due to interferon-alpha.,Restless legs syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Restless legs syndrome may thus be an adverse effect of IFN alpha treatment.,Restless legs syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Many clinicians appear to be concerned about the potential hepatotoxicity of the opiate antagonist naltrexone (NTX) and this may be one reason why it is not used more widely in treating both heroin and alcohol abusers.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a heroin abuser in whom clinical and laboratory manifestations of acute hepatitis B and C appeared a few days after the insertion of a subcutaneous naltrexone implant.,Hepatic necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sweet's syndrome associated with sargramostim (granulocyte-macrophage colony stimulating factor) treatment.,Acute febrile neutrophilic dermatosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Sweet's syndrome is an acute febrile neutrophilic dermatosis that is a known complication of the administration of filgrastim, a drug that causes increased neutrophil proliferation and differentiation.",Acute febrile neutrophilic dermatosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of Sweet's syndrome in association with sargramostim treatment following chemotherapy for acute myelogenous leukemia.,Acute febrile neutrophilic dermatosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sudden cardiac death due to hypersensitivity myocarditis during clozapine treatment.,Hypersensitivity myocarditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The autopsy findings and a detailed medical history supported the conclusion that clozapine-induced hypersensitivity myocarditis was the most likely cause of death.,Hypersensitivity myocarditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The case concerns the sudden death of a 29-year-old male during clozapine therapy started 2 weeks before.,Sudden Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Purple glove syndrome, named for its distinctive purple discoloration and swelling of the hands in the distribution of a glove, is an uncommon complication of intravenous phenytoin administration through small dorsal veins of the hands.",Purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The findings were judged to be consistent with soft-tissue injury associated with intravenous administration of phenytoin, also termed purple glove syndrome.",Purple glove syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Our patient was a 72-year-old man with advanced Parkinson's disease (PD) who received levodopa and anti-cholinergic drugs and whose head had become almost completely bald.,Alopecia totalis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient with monocular open-angle glaucoma had trichiasis, a condition associated with the use of a prostaglandin analog.",Trichiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Increased lash length, thickness, and pigmentation are well-documented side effects of prostaglandin analog glaucoma drops.",Eyelash changes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Trichiasis associated with prostaglandin analog use.,Trichiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fatal pulmonary fibrosis associated with BCNU: the relative role of platelet-derived growth factor-B, insulin-like growth factor I, transforming growth factor-beta1 and cyclooxygenase-2.",Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary fibrosis is a severe complication associated with bis-chloronitrosourea (BCNU) therapy.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These novel findings may offer specific therapeutic targets in the treatment of BCNU-associated pulmonary fibrosis.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We further used immunohistochemistry (IHC) to examine the relative role of platelet-derived growth factor-B (PDGF-B), insulin-like growth factor I (IGF-I), transforming growth factor-beta1 (TGF-beta1) and cyclooxygenase-2 (COX-2) in the pathogenesis of BCNU-related pulmonary fibrosis.",Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report here a 26-year-old female with diffuse large B-cell lymphoma who died of severe pulmonary fibrosis 81 days after the administration of high-dose BCNU (600 mg/m2).,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dorzolamide-induced choroidal detachment in a surgically untreated eye.,Choroidal detachment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: A 76-year-old woman with primary open-angle glaucoma and no history of ocular surgery developed a choroidal detachment 12 hours after initiation of therapy with dorzolamide eye drops.,Choroidal detachment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We document the abrupt development of an extensive choroidal detachment after initiation of dorzolamide therapy in a surgically untreated eye with primary open-angle glaucoma.,Choroidal detachment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Deepening of lid sulcus from topical bimatoprost therapy.,Periorbital fat atrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In each of the three reported patients, alteration of eyelid appearance with deepening of the lid sulcus was evident as the result of topical bimatoprost therapy.",Eyelid vellus hair changes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lichen planus induced by hepatitis B vaccination: a new case and review of the literature.,Lichen planus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Case report: life-threatening hypoglycaemia associated with sulfadoxine-pyrimethamine, a commonly used antimalarial drug.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this report, we present a case of hypoglycaemic coma associated with SP, an adverse reaction that is likely to be underreported and expected to occur with greater frequency as the use of SP increases.",Hypoglycaemic coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Initial treatment with heparin was substituted with thrombolysis, which resulted in clinical improvement and dissolution of right heart thrombus but was followed by fatal intracerebral haemorrhage.",Cerebral Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Extensive forearm deep venous thrombosis following a severe infliximab infusion reaction.,Deep vein Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here we describe a patient with Crohn's disease who developed a severe infliximab infusion reaction (IIR), complicated 1 day later by severe swelling of the forearm and hand ipsilateral to the site of infliximab infusion.",Infusion related reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The site of thrombosis and the chronological relationship with the IIR implicates a hypersensitivity to infliximab in the causation of the venous thrombosis in this case.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After 3- to 13-month period of therapy without indapamide, glucose levels of all patients decreased and diabetes disappeared.",Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After stopping indapamide, glucose tolerance impairing may be reversed.",Glucose tolerance impaired
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Therapy with indapamide may induce diabetes in essential hypertension patients.,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: To study therapy with indapamide impairing carbohydrate metabolism in essential hypertension patients and achieve earlier prevention, diagnoses and treatment of diabetes induced by indapamide.",Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Possible induction of diabetes by treatment of hypertension with indapamide (with four case reports).,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: After 4- to 14-month period of therapy with the combination of indapamide (2.5 mg/day) and fosinopril (10 mg/day) in three patients and 6-month period of monotherapy with indapamide (2.5 mg/day) in one patient, glucose levels of all patients increased and achieve criteria of diabetes diagnoses.",Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Despite a hematologic response in all 3 patients, none of them achieved cytogenetic remission, and all progressed to blast crisis at 7 to 10 months of imatinib therapy.",Blast cell crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition to disease refractoriness, rare instances of disease progression from chronic phase to blast crisis during imatinib therapy have recently been anecdotally reported.",Blast cell crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVES: To describe the clinicopathologic features of 3 patients with CML who rapidly progressed from chronic phase to blast crisis while taking imatinib and to perform a review of the literature.,Blast cell crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Our findings suggest that significant progression of marrow reticulin fibrosis during imatinib therapy can be an indicator for a return or progression of CML and, in some patients with CML, imatinib may promote cytogenetic clonal evolution, resulting in a poor response to treatment.",Bone marrow reticulin fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Progression of chronic myeloid leukemia to blast crisis during treatment with imatinib mesylate.,Blast cell crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Easily reversible hypoxemia and hypotension induced by nimodipine.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this paper we report a case of nimodipine overdosage resulting in prolonged hypotension and hypoxemia, which was successfully treated with calcium gluconate.",Hypoxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Refractory hypoglycemia from ciprofloxacin and glyburide interaction.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a case of a diabetic patient taking glyburide who was prescribed ciprofloxacin and developed prolonged hypoglycemia, which persisted for over 24 hours.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Aminophylline hypersensitivity apparently due to ethylenediamine.,Drug hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of ethylenediamine-induced delayed hypersensitivity reaction in a 46-year-old woman who received parenteral aminophylline for an acute asthma exacerbation.,Type IV hypersensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,L-asparaginase-induced severe necrotizing pancreatitis successfully treated with percutaneous drainage.,Pancreatitis necrotising
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Most cases of pancreatitis associated with L-asparaginase toxicity are self-limiting and respond favorably to nasogastric decompression and intravenous hyperalimentation.,Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pancreatitis has been noted to be a complication in 2-16% of patients undergoing treatment with L-asparaginase for a variety of pediatric neoplasms.,Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a pediatric patient with leukemia and a severe, L-asparaginase-induced necrotizing pancreatitis, treated successfully with percutaneous drainage used to flush the infected necrotic parts.",Pancreatitis necrotising
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disulfiram-induced fulminant hepatic failure in an active duty soldier.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fulminant hepatic failure is a rare complication of disulfiram treatment for alcoholism.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case describes fulminant hepatic failure in a patient taking disulfiram with no previous liver disease and report of being compliant with alcohol abstinence.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Tiagabine overdose causes an unusual array of neurological symptoms, many similar to reported adverse effects during therapeutic use.",Neurological symptom
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case of sideroblastic anemia is presented in a patient with a left ventricular assist device drive-line infection who was receiving linezolid, an antibiotic used for serious infections with gram-positive organisms.",Sideroblastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"As linezolid has been shown to have hematologic side effects, blood count monitoring is recommended in patients receiving this drug for long-term therapy.",hematologic side effects
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sideroblastic anemia due to linezolid in a patient with a left ventricular assist device.,Sideroblastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acute renal insufficiency is known to occur in patients who are taking ciprofloxacin, particularly the elderly.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ciprofloxacin-induced renal insufficiency in cystic fibrosis.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Multiple mechanisms for ciprofloxacin-induced nephrotoxicity have been proposed.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two young patients with cystic fibrosis who presented with acute renal insufficiency after 2-3 weeks of oral ciprofloxacin therapy.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sensory neuropathy revealing necrotizing vasculitis during infliximab therapy for rheumatoid arthritis.,Vasculitis necrotising
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe 2 patients with severe erosive rheumatoid arthritis and rheumatoid vasculitis, respectively, in whom infliximab therapy was associated with peripheral neuropathy due to necrotizing vasculitis in one patient and to progression of preexisting mononeuritis multiplex in the other.",Vasculitis necrotising
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Progressive anemia following combination therapy with interferon-alpha and interleukin-2 in a patient with metastatic renal cell carcinoma.,Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of severe anemia, which responded well to steroid therapy, in a patient receiving IL-2 plus IFN-alpha for metastatic renal cell carcinoma.",Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"An objective causality assessment indicated a probable relationship between clotting abnormality and warfarin administration, although the degree of elevation of the INR was unusual in the light of the daily warfarin dose and duration of its exposure.",Coagulopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Based on the clinical status of the patient, it was suspected that several conditions contributed to the abnormal hypersensitivity to warfarin.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Despite the low dosage of warfarin, international normalized ratio (INR) was markedly elevated from 1.15 to 11.28 for only 4 days, and bleeding symptoms concurrently developed.",Haemorrhage symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In view of our experience in the present case, it should be stressed that close monitoring of coagulation capacity is necessary in critically ill patients in order to avoid fatal haemorrhage after initiating warfarin therapy regardless of the dosage.",Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Unusual hypersensitivity to warfarin in a critically ill patient.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report an allogeneic bone marrow transplant recipient who developed CMV infection refractory to sequential therapy with ganciclovir, foscarnet, and cidofovir.",Cytomegalovirus infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,5-fluorouracil (5-FU)-associated peripheral neuropathy is an uncommon event.,Neuropathy peripheral peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"During analysis of 28 patients receiving CAP with concomitant radiation (XRT) for pancreatic cancer (resected or locally advanced), two patients developed signs and symptoms consistent with peripheral neuropathy.",Neuropathy peripheral peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Knowledge regarding potential adverse effects of CAP is paramount and dose modification is indicated with development of neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Neurologic symptoms resolved after stopping CAP for 4 weeks in Patient A, with no recurrence after reinitiating CAP alone at 2000 mg/m2.",Neuropathy peripheral peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patient A reported right leg weakness (foot drop) during week 4 of CAP-XRT (1600 mg/m2).,Peroneal nerve palsy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patient B developed perioral and upper extremity paresthesias during the fourth cycle of CAP alone (2500 mg/m2).,Paraesthesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Peripheral neuropathy associated with capecitabine.,Neuropathy peripheral peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We conclude peripheral neuropathy with 5-FU is rare.,Neuropathy peripheral peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe hypo-alpha-lipoproteinemia during treatment with rosiglitazone.,Hypo HDL cholesterolaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report three patients, all of whom had preexisting diabetic dyslipidemia, who showed a profound reduction in plasma HDL cholesterol and apolipoprotein AI levels soon after the initiation of rosiglitazone therapy.",High density lipoprotein decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe leukopenia associated with mild hepatotoxicity in an HIV carrier treated with nevirapine.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report an HIV-infected woman who developed mild leukopenia as the first sign of a nevirapine-related adverse event, which was followed by skin and hepatic toxicity associated with a more severe leukopenia.",Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In all cases, drugs in addition to quetiapine were detected, but in cases #1 and #2, the cause of death was considered to be a quetiapine overdose and the other drugs were not considered to be contributory.",Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These cases were chosen for study because they were all deaths as a result of suicidal ingestion of drugs in which quetiapine was considered a significant factor.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present three cases from the Provincial Toxicology Center of British Columbia, Canada in which suicidal overdose deaths were associated with quetiapine.",Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,After approximately two weeks of sertraline treatment he noted an intense itching sensation in his scalp after eating a piece of chocolate cake.,Pruritus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Itch and skin rash from chocolate during fluoxetine and sertraline treatment: case report.,Pruritus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary lymphohistiocytic reactions temporally related to etanercept therapy.,Lymphocytic infiltration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This report details the pulmonary pathologic findings in four patients with rheumatoid arthritis, who developed new onset of pulmonary signs and symptoms with alveolar infiltrates temporally related to the institution of etanercept therapy.",Lung infiltration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Paradoxical cerebral cortical hyperexcitability following flupirtine overdose.,Agitation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a patient with increased cerebral cortical excitability following intoxication with flupirtine, a centrally acting analgesic and antispastic drug.",Agitation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,AIM: Report of a case of a woman patient who developed celiac disease after pegylated interferon alpha-2a and ribavirin use for chronic hepatitis C.,Coeliac disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Celiac disease onset after pegylated interferon and ribavirin treatment of chronic hepatitis C.,Coeliac disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"PATIENT AND METHOD: A 34-year-old woman with chronic hepatitis C, genotype 3, receiving pegylated interferon alpha-2a and ribavirin for 6 months, developed progressive malaise and anemia 6 months after the end of treatment.",Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present two cases of anaphylaxis under anaesthesia where return of spontaneous circulation was refractory to epinephrine, but occurred following the administration of the alpha-agonist metaraminol.",Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this article, we describe another case of subcutaneous changes following repeated glatiramer acetate injection, presented as localized panniculitis in the area around the injection sites, in a 46-year-old female patient who was treated with glatiramer acetate for 18 months.",Panniculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Localized panniculitis and subsequent lipoatrophy with subcutaneous glatiramer acetate (Copaxone) injection for the treatment of multiple sclerosis.,Lipoatrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In a postoperative patient with pre-existent myasthenia gravis, oral verapamil caused a marked exacerbation in myasthenic weakness.",Myasthenia gravis crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In four patients, thrombosis occurred 2-45 days after severe hepatic veno-occlusive disease (HVOD) secondary to intensive chemotherapy containing busulfan.",Venoocclusive liver disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PVT during chemotherapy in children is a rare event and appears to be closely related to intensive chemotherapy containing busulfan and to be associated with HVOD.,Venoocclusive liver disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here, we describe a case of Vogt-Koyanagi-Harada disease occurring 4 months after the start of interferon alpha treatment, probably induced by the immunomodulatory effects of interferon.",Vogt-Koyanagi-Harada disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Retinal abnormalities, including retinal hemorrhage and ""cotton-wool"" spots, often occur within the first 8 weeks in the course of interferon therapy in patients with chronic hepatitis C.",Retinal exudates
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Vogt-Koyanagi-Harada disease occurring during interferon alpha therapy for chronic hepatitis C.,Vogt-Koyanagi-Harada disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute hepatic failure is a rare and potentially lethal complication of propylthiouracil (PTU) use for hyperthyroidism.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After an extensive review of the literature, we believe that this is the first communication of the successful use of amiodarone to control hyperthyroidism in a patient with PTU-induced fulminant hepatitis.",Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a 20-year-old woman with Basedow-Graves' disease who developed PTU-induced fulminant hepatitis, which progressed to acute hepatic failure with grade III hepatic encephalopathy.",Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Epstein-Barr virus-associated lymphoproliferative disorder in a patient with rheumatoid arthritis on methotrexate and rofecoxib: idiosyncratic reaction or pharmacogenetics?,Epstein-Barr virus associated lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Methotrexate (MTX) is a commonly used second line agent for RA, and there have been several recent reports of Epstein-Barr virus (EBV)-associated polyclonal B cell lymphoproliferative disorder in MTX-treated RA patients.",Epstein-Barr virus associated lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Previous studies have demonstrated the interaction of MTX and a variety of non-steroidal, anti-inflammatory drugs (NSAIDs) with various clinical manifestations including acute renal failure, pancytopenia, vomiting, diarrhea, elevated liver transaminases, jaundice, mucosal ulcerations, and pyrexia.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We hypothesize that decreased renal elimination of MTX induced by the COX-2 inhibitor resulted in enhanced hematopoietic toxicity and immunosuppression causing the EBV-associated lymphoproliferative disease.,Epstein-Barr virus associated lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBSERVATIONS: We observed aggravation and spreading of a psoriatic plaque when treated topically with the toll-like receptor (TLR) 7 agonist imiquimod.,Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors.,Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since imiquimod induces large amounts of type I interferon production from TLR7-expressing plasmacytoid dendritic cell precursors (PDCs), the natural interferon-producing cells of the peripheral blood, we asked whether PDCs are present in psoriatic skin.",Interferon alpha level increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The exacerbation of psoriasis was accompanied by a massive induction of lesional type I interferon activity, detected by MxA expression after imiquimod therapy.",Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Vision declined after treatment with methylprednisolone, after which fundus examination became consistent with progressive outer retinal necrosis.",Visual acuity reduced
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Allergic side effects of AZA are rare, and reported allergic skin eruptions from AZA are very limited in Japan.",Dermatitis allergic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DLST is a good diagnostic tool for AZA allergy, especially for severe drug allergy cases.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug eruption caused by azathioprine: value of using the drug-induced lymphocytes stimulation test for diagnosis.,Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report AZA-induced drug eruption that developed in two cases of systemic scleroderma with polymyositis.,Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tardive dyskinesia in 2 patients treated with ziprasidone.,Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two of our patients developed TD after 23 months and 34 months of ziprasidone monotherapy, respectively.",Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ziprasidone is an atypical antipsychotic drug that is believed to have a low propensity for inducing extrapyramidal symptoms, including tardive dyskinesia (TD).",Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Asthenozoospermia: possible association with long-term exposure to an anti-epileptic drug of carbamazepine.,Asthenospermia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient was found to have no motile sperm with a normal sperm count, while taking a dose of 400 mg/day of carbamazepine.",Asthenospermia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Scrotal ulceration induced by all-trans retinoic acid in a patient with acute promyelocytic leukemia.,Scrotal Ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The ulcer did not respond to antibiotic treatment and healed shortly after withholding ATRA.,Ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the development of scrotal ulcer in a patient with acute promyleocytic leukemia (APL) within 10 days of treatment with ATRA at a dose of 40 mg orally twice daily.,Scrotal Ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of clozapine-induced tonic-clonic seizures managed with valproate: implications for clinical care.,Generalised tonic-clonic seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Following discontinuation of clozapine, she was rechallenged and again was observed to have seizures.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"These findings suggest that clozapine-induced seizures can be successfully treated, that gradual dose titration can reduce the likelihood of further episodes of seizures and that concomitant use of a suitable mood stabilizer/anti-epileptic medication can improve the outcome of treatment-resistant schizophrenia.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of clozapine-induced seizures in a patient with treatment-resistant schizophrenia.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Symptoms and pathologic changes of colitis are associated with exposure to rofecoxib.,Colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVES: To describe clinical and pathologic findings in patients noted to develop lower gastrointestinal symptoms when exposed to rofecoxib.,Lower gastrointestinal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Three patients who developed symptoms of inflammatory bowel disease (IBD) during rofecoxib exposure are described along with pathology findings.,Inflammatory bowel disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To the best of our knowledge, this is the first reported patient with captopril-induced pemphigus in whom no new lesions developed after subsequent treatment with enalapril.",Pemphigus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of drug-induced pemphigus caused by an angiotensin-converting enzyme inhibitor, captopril.",Pemphigus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Neuropathy is a significant side effect of thalidomide therapy, which may limit its clinical use.",Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thalidomide neuropathy in childhood.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thalidomide neuropathy is often associated with proximal weakness and may progress even after discontinuation of treatment, in the phenomenon of 'coasting'.",Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thalidomide was withdrawn from world markets in 1961 following recognition of its teratogenic effects.,Teratogenicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report four cases of sensorimotor axonal neuropathy in children aged 10-15 years, treated with thalidomide for myxopapillary ependymoma, Crohn's disease and recurrent giant aphthous ulceration.",Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cerebral edema associated with Gliadel wafers: two case studies.,Brain oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Following are two clinical case reports demonstrating profound cerebral edema associated with implantation of Gliadel wafers.,Brain oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"While the introduction of carmustine wafers (Gliadel wafers) into the tumor resection cavity has been shown to be a beneficial therapy for malignant glioma, it is recognized that clinically significant cerebral edema is a potential adverse effect.",Brain oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cis-retinoic acid (RA) may further increase the risk of developing BMTN.,Meningitis bacterial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is likely that RA contributed to the deterioration in renal function in these patients.,Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Retinoic acid may increase the risk of bone marrow transplant nephropathy.,Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The occurrence of BMTN in two children treated with RA in our unit is unlikely to be coincidental.,Meningitis bacterial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,He developed a late secondary infection in some sites treated with imiquimod.,Infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 64-year-old man with schizophrenia developed myoclonic jerks when given higher doses of quetiapine.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Quetiapine-induced myoclonus.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of myoclonus induced by quetiapine.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma.,Myelodysplastic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 44-year-old woman with t-MDS (refractory anemia with excess blasts) following treatment of recurrent anaplastic astrocytoma with temozolomide (TMZ).,Myelodysplastic syndrome with excess blasts
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Typically, drug-induced neutropenia occurs in a patient receiving a semisynthetic penicillin for two weeks or more.",Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Livedo reticularis associated with interferon alpha therapy in two melanoma patients.,Livedo reticularis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These cases highlight the occurrence of livedo reticularis as an uncommon side-effect of interferon alpha treatment.,Livedo reticularis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two patients who developed intense livedo reticularis clearly related to the administration of interferon alpha 2b as an adjuvant therapy for melanoma.,Livedo reticularis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: This rare case of PTU-induced ANCA-associated vasculitis manifested with ototoxicity in combination with systemic involvement.,Anti-neutrophil cytoplasmic antibody positive vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the case of a young woman with Graves' disease in whom ototoxicity developed because of propylthiouracil (PTU)-induced antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis.,Anti-neutrophil cytoplasmic antibody positive vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propylthiouracil-induced sensorineural hearing loss associated with antineutrophil cytoplasmic antibodies.,Anti-neutrophil cytoplasmic antibody positive vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: In a 22-year-old Thai woman with Graves' disease, tinnitus, hearing impairment in the left ear (with progression to the right ear), and vertigo developed after 3 years of therapy with PTU.",Hypoacusis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The hearing impairment and tinnitus were gradually reduced after PTU withdrawal and corticosteroid and azathioprine treatment.,Hypoacusis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anti-tuberculous drugs had been stopped on the 2nd day of therapy due to development of optic neuritis secondary to ethambutol administration at another hospital.,Optic neuritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"During the anti-tuberculous therapy, visual loss can be related to ethambutol toxicity or the tuberculosis infection itself.",Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition, ethambutol rarely causes visual loss during the early period or when given at lower doses.",Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Flucloxacillin-induced aplastic anaemia and liver failure.,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is well-recognized that flucloxacillin may occasionally result in fatal hepatic injury.,Drug-induced Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a 40-year-old woman who developed fulminant hepatic failure and aplastic anaemia following a course of oral flucloxacillin.,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Four days after intravenous Zoledronic acid, the patient presented to emergency room with complaints of carpopedal spasm and bronchospasm.",Bronchospasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Zoledronic acid-induced severe hypocalcaemia in a prostate cancer patient with extensive osteoblastic bone metastases.,Hypocalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case report describes an adolescent with severe lupus erythematosus who received cyclophosphamide (CY) paired with taste (cod liver oil) and smell (rose perfume) as conditioned stimuli.,Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mucosal pigmentation after oral lichen planus treatment with topical tacrolimus.,Mucosal Pigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The relation between tacrolimus treatment and staining was suggested by the appearance of pigmentation during topical tacrolimus treatment and its clinical disappearance when treatment was stopped.,Pigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first histopathologically documented case of oral mucosa pigmentation after OLP treatment with topical tacrolimus.,Pigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Recently, some studies have also reported association between patients with juvenile rheumatoid arthritis (JRA) treated with Methotrexate (MTX) and malignant lymphoma developing.",Lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Risperidone is a frequently used member of a new class of atypical antipsychotics-the serotonin-dopamine antagonists (SDAs)-due to its comparatively high efficacy and low D2/5HT2 binding ratio, which results in a low incidence of extrapyramidal side effects including tardive dyskinesia (TD).",Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Risperidone withdrawal-related respiratory dyskinesia: a case diagnosed by spirography and fibroscopy.,Respiratory Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors present an elderly patient with mixed dementia who developed TD at multiple sites, (including respiratory dyskinesia [RD], limb dyskinesia, and orofacial dyskinesia) following abrupt withdrawal of risperidone therapy.",Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this study, we report on three individual patients who received BTX-B and who subsequently developed parasympathetic dysfunction of the visual system after injections of BTX-B at remote sites.",Nervous system disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To date, there have been few reports of visual disturbances associated with BTX-B use.",Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Visual system side effects caused by parasympathetic dysfunction after botulinum toxin type B injections.,Nervous system disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Enalapril-induced anemia in two kidney transplant recipients.,Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two renal transplant patients developed anemia during treatment of hypertension with enalapril medication.,Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 74-year-old hypercholestrerolaemic woman taking cerivastatin (0.15 mg/day) for 22 days complained of general muscle weakness and muscle pain.,Myalgia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on a patient who developed acute rhabdomyolysis after taking cerivastatin.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carboplatin hypersensitivity induced by low-dose paclitaxel/carboplatin in multiple platinum-treated patients with recurrent ovarian cancer.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, one patient exhibited severe hypersensitivity reactions including cardiac arrest and apnea, and another four patients developed eruptions, hypotension, and tachycardia soon after administration of CBDCA.",Apnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Our report suggested that CBDCA hypersensitivity was correlated with the total dose of previously administered platinum agents and that CBDCA should be excluded in patients who have received multiple platinum-based chemotherapy, even in platinum-sensitive cases, because CBDCA hypersensitivity can occur even with low-dose CBDCA administration.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report five cases of carboplatin (CBDCA) hypersensitivity after weekly low-dose paclitaxel (60 mg/m2)/CBDCA (area under the concentration curve = 2) therapy in patients with recurrent ovarian cancer receiving multiple platinum-based chemotherapy.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,TREATMENT/OUTCOME: Standard anti-tuberculosis therapy was administered but was complicated by interaction with cyclosporine and drug-induced cholestasis.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chronic fentanyl application induces adrenocortical insufficiency.,Adrenocortical insufficiency acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of a 64-year-old man with secondary adrenocortical insufficiency who has been on a chronic transdermal fentanyl treatment because of sciatic pain syndrome.,Adrenocortical insufficiency acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fluphenazine-induced neuroleptic malignant syndrome in a schizophrenic patient.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of neuroleptic malignant syndrome (NMS) associated with fluphenazine in a schizophrenic patient and review the literature related to this condition.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intraventricular vancomycin-induced cerebrospinal fluid eosinophilia: report of two patients.,Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We propose a mechanism of vancomycin-induced mast cell degranulation and subsequent release of eosinophil chemotactic factor as a cause of CSFE.,Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two cases of cerebrospinal fluid eosinophilia (CSFE) secondary to the intraventricular administration of vancomycin.,Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Successful recovery from interstitial pneumonitis, induced by bicalutamide and leuprorelin acetate given as treatment for prostate cancer.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of interstitial pneumonitis induced by bicalutamide and/or leuprorelin acetate given as therapy for prostate cancer, in which the pneumonitis was successfully managed by steroid treatment.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: In these 3 cases, the unique positive ocular finding was corneal endothelial deposits, which may be related to the use of rifabutin.",Corneal deposits
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Corneal endothelial deposits associated with rifabutin use.,Corneal deposits
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: The aim of this study was to report on the possible development of corneal endothelial deposits resulting from the use of rifabutin.,Corneal deposits
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: All cases developed corneal endothelial deposits after previous use of rifabutin.,Corneal deposits
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE: A malignant mixed mesodermal tumor was diagnosed in a 64-year-old woman with a bicornuate uterus while she was taking raloxifene for osteoporosis prevention.,Uterine cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: There may be an association between raloxifene and the development of malignant mixed mesodermal tumor.,Uterine cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Malignant mixed mullerian tumor of the uterus in a patient taking raloxifene.,Uterine cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of a women in whom a malignant mixed mesodermal tumor was diagnosed while she was taking raloxifene, which is also a selective estrogen receptor modulator.",Uterine cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Herein we report four patients who underwent liver transplantation and developed neutropenia while receiving MMF.,Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mycophenolate mofetil-induced neutropenia in liver transplantation.,Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The mean time from starting MMF to the development of neutropenia was 4 months.,Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The side effects of MMF, such as bone marrow toxicity, have been reported.",Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A previous review described data on 15 patients who experienced acute hemoglobinemia or hemoglobinuria following anti-D IGIV administration for ITP or secondary thrombocytopenia.,Haemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disseminated intravascular coagulation associated with acute hemoglobinemia or hemoglobinuria following Rh(0)(D) immune globulin intravenous administration for immune thrombocytopenic purpura.,Haemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"That review suggested that patients receiving anti-D IGIV be monitored for those and other potential complications of hemoglobinemia, particularly disseminated intravascular coagulation (DIC).",Disseminated intravascular coagulation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The purpose of this review is to increase awareness among physicians and other health care professionals that DIC may be a rare but potentially severe complication of anti-D IGIV treatment.,Disseminated intravascular coagulation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This review presents the first case series of DIC associated with acute hemoglobinemia or hemoglobinuria following anti-D IGIV administration for ITP.,Haemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After the second infliximab infusion, he was found to have a severe transient neutropenia (0.5 x 10(9)/L).",Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug-induced agranulocytosis during treatment with infliximab in enteropathic spondyloarthropathy.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These data indicated that infliximab possibly triggered production of granulocyte and neutrophil autoantibodies with resultant autoimmune agranulocytosis.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, peripheral neuropathy and bone marrow depression led to linezolid withdrawal in seven patients, and neuropathy may not be fully reversible in all patients.",Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Six patients developed peripheral neuropathy and five patients bone marrow depression, blood transfusions were given to three patients and in all five patients bone marrow function normalized after cessation of linezolid.",Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case of high-grade endometrial stromal sarcoma, confined into an intrauterine polypoid growth, in a woman with a history of breast cancer who was treated with adjuvant tamoxifen.",Endometrial stromal sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,High-grade endometrial stromal sarcoma after tamoxifen therapy for breast cancer.,Endometrial stromal sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In deciding if tamoxifen therapy is warranted, all potentially life-threatening adverse events associated with tamoxifen should be considered, including endometrial adenocarcinoma or uterine sarcoma.",Endometrial stromal sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After only the third dose of pentamidine, it was noted that the patient's heart rate had decreased to 48 beats/minute.",Heart rate decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although various manifestations of pentamidine-induced cardiotoxicity have been reported, to our knowledge, second-degree heart block associated with this agent has not been described.",Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinicians should be vigilant when monitoring for cardiotoxicity in patients receiving pentamidine throughout the duration of therapy.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Early-onset pentamidine-associated second-degree heart block and sinus bradycardia: case report and review of the literature.,Atrioventricular block second degree
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Falling backward in two elderly patients taking bupropion.,Fall
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Both patients experienced a previously unreported side effect--falling backward--associated with bupropion use.,Fall
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The knowledge concerning VGB-associated visual dysfunction in pediatric patients, particularly in those who have been exposed to VGB in utero is limited.",Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Vigabatrin-induced visual field defects are at present the most important safety issue in the use of the drug.,Visual field defect
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: Interferon (IFN)-associated retinopathy is typically characterized by retinal hemorrhages and cotton wool spots at the posterior fundus, but visual function is usually maintained.",Retinal exudates
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinical course of macular edema in two cases of interferon-associated retinopathy observed by optical coherence tomography.,Macular oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: During and after IFN therapy, OCT is a useful examination technique for revealing macular edema in patients who have decreased vision.",Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ophthalmologists should be aware of the ocular side effects of IFN therapy and carefully monitor patients for the possible occurrence of hypoalbuminemia and thrombocytopenia.,Hypoalbuminaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The former patient had complained once that his visual acuity had decreased after the termination of IFN therapy, and the latter patient complained twice during IFN therapy that his visual acuity had decreased.",Visual acuity reduced
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"With the use of optical coherence tomography (OCT), two patients with IFN-associated retinopathy who had developed macular edema and reduced visual acuity during the clinical course of IFN therapy were observed.",Macular oOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Late development of diabetes mellitus after interferon-alfa and ribavirin therapy for chronic hepatitis C: a case report.,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the late development of immune-mediated diabetes mellitus after completion of alfa-interferon therapy for hepatitis C in an Asian patient.,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cutaneous necrosis after injection of polyethylene glycol-modified interferon alfa.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Cutaneous necrosis as a result of interferon alfa is an infrequent complication with unknown pathogenesis, in which a cutaneous local immune-mediated inflammatory process might be involved.",Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report 5 patients (3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We review the literature on previously reported cases of cutaneous necrosis after injection of standard interferon alfa or pegylated interferon alfa-2b and discuss the different pathophysiologic mechanisms that might be involved.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Potential mechanisms involved in the occurrence of ischemic colitis in patients receiving tegaserod are also discussed.,Colitis ischaemic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tegaserod-associated ischemic colitis.,Colitis ischaemic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe the development of ischemic colitis in a woman who was treated with tegaserod and review the relationship among ischemic colitis, tegaserod use, and irritable bowel syndrome.",Irritable bowel syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 57-year-old man developed chronic, watery diarrhea four weeks after Helicobacter pylori eradication therapy including lansoprazole followed by lansoprazole monotherapy for gastroesophageal reflux disease.",Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lansoprazole-associated collagenous colitis: a case report.,Colitis microscopic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The reported case represents an unusual association between medication with the proton pump inhibitor lansoprazole and the development of collagenous colitis suggesting the importance of evaluation of drug use in patients with microscopic colitis.,Colitis microscopic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,46-year-old woman developed painful ulcers over her lower abdomen in the form of reticulate erythema after injecting interferon beta-1b subcutaneously for multiple sclerosis.,Ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Abdominal wall ulceration and mucinosis secondary to recombinant human interferon-beta-1b.,Ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Itraconazole-related increased vincristine neurotoxicity: case report and review of literature.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nineteen cases of unusual enhanced vincristine neurotoxicity related to itraconazole have been reported in children.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ten days after itraconazole was started, he developed paralytic ileus, neurogenic bladder, mild left ptosis, and absence of deep reflexes, with severe paralysis of the lower extremities and mild weakness of the upper extremities.",Areflexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE REPORT: We report a case of intracerebral hemorrhage occurring in a middle-aged man who suffered from chronic sinusitis and had been ingesting pseudoephedrine daily for one year.,Cerebral haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Only one report links phenylpropanolamine consumption to an intracerebral hemorrhage in a patient with an AVM.,Cerebral haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pseudoephedrine-induced hemorrhage associated with a cerebral vascular malformation.,Congenital cerebrovascular anomaly
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since 1979, over 30 published case reports have documented the relationship between phenylpropanolamine and stroke.",Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is a case of pseudoephedrine-induced intracerebral hemorrhage in a patient with an underlying vascular malformation.,Cerebral haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rapid onset of quetiapine-induced diabetic ketoacidosis in an elderly patient: a case report.,Diabetic ketoacidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of reversible DKA and new-onset DM that developed in a demented patient who was treated with quetiapine for 14 days.,Diabetic ketoacidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary leukostasis secondary to all-trans retinoic acid in the treatment of acute promyelocytic leukemia in first relapse.,Leukostasis syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Eruptive epidermoid cysts resulting from treatment with imiquimod.,Dermoid cyst
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: A 79-year-old woman being treated with imiquimod 5 days per week for a nodular basal cell developed a verrucous plaque over the treatment area after 7 weeks of therapy.,Skin papilloma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The multiple comedones and ruptured epidermoid cysts are newly reported adverse effects of imiquimod therapy.,Acne
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report an unusual case of massive fluoxetine ingestion resulting in neurological and cardiovascular toxicity resulting in death.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child.,Hepatocellular injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The case reported here is of a child given a large dose of intravenous iron sucrose (16 mg/kg) over 3 hours, who subsequently developed features of systemic iron toxicity.",Systemic toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Five personal observations of an acute amnestic episode in younger individuals after intake of clioquinol are described together with three observations from the medical literature.,Amnesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The clinical aspect closely resembled classical transient global amnesia but the episode after clioquinol lasted longer (24 hours to three days) and a more or less extensive retrograde amnesia persisted permanently.,Retrograde Amnesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient global amnesia after clioquinol: five personal observations from outside Japan.,Transient global Amnesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the other patient, a 78-year-old woman, Neisseria mucosa knee arthritis occurred after a single sodium hyaluronate injection.",Arthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One patient was an 80-year-old woman who was admitted for Staphylococcus aureus knee arthritis after several intraarticular injections of sodium hyaluronate and corticosteroids.,Arthritis bacterial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Septic knee arthritis after intra-articular hyaluronate injection.,Arthritis bacterial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute dystonia induced by lamivudine.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"ADR induced by drug treatment can be a side effect of treatment with antipsychotic drugs and other drugs; however, there have been no reports of lamivudine-induced ADR in the English literature.",Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report two cases of acute dystonic reactions (ADRs) as a side effect of lamivudine.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors think that although lamivudine is widely used and well tolerated, it can cause ADRs, which are reversible after drug withdrawal.",Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pleuropulmonary fibrosis after long-term treatment with the dopamine agonist pergolide for Parkinson Disease.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: To our knowledge, this is the first published case report of an adolescent girl with a mitochondrial disorder and depression who displayed both new-onset psychotic and increased mood symptoms during treatment with risperidone.",Affective disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Risperidone-induced psychosis and depression in a child with a mitochondrial disorder.,Depression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal radiation myelopathy after high-dose busulfan and melphalan chemotherapy and radiotherapy for Ewing's sarcoma: a review of the literature and implications for practice.,Radiation myelopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gemcitabine-induced pericardial effusion and tamponade after unblocked cardiac irradiation.,Pericardial Effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gemcitabine therapy has been associated with radiation recall reactions when used in the treatment of carcinoma.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Physicians should be aware of the potential for developing a gemcitabine-induced radiation recall reaction resulting in hemodynamically significant pericardial effusion.,Pericardial Effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report four cases of hemodynamically significant pericardial effusion in patients with refractory lymphoma who were receiving gemcitabine, all of whom had a history of mediastinal radiation without subcarinal blocking.",Pericardial Effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with generalized MG was effectively managed with MM but developed CNS lymphoma after 3 years of treatment.,Central nervous system lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil.,Central nervous system lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Primary CNS lymphoma regressed on withdrawal of MM.,Central nervous system lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Baclofen withdrawal: a cause of prolonged fever in the intensive care unit.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Baclofen withdrawal syndrome resulting from underdosing of oral baclofen should be considered as a potential source of prolonged fever in the intensive care unit.,Withdrawal syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient continued to have fever and autonomic instability without evidence of infection which entirely resolved within 24 hours of reinstitution of full preadmission dosing of oral baclofen.,Autonomic nervous system imbalance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of baclofen withdrawal syndrome resulting from oral baclofen underdosing.,Withdrawal syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After discontinuing captopril and starting systemic steroids, her symptomatology rapidly improved, and her eosinophilia and radiographic abnormalities both resolved.",Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Captopril-induced pulmonary infiltrates with eosinophilia in an infant with congenital heart disease.,Eosinophilic pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of an infant with complex congenital heart disease who was placed on captopril for afterload reduction following cardiac surgery and subsequently developed pulmonary infiltrates with eosinophilia.,Eosinophilic pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Can propofol precipitate pancreatitis in patients with Cushing's syndrome?,Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since elevated cortisol levels in Cushing's disease poses a threat for pancreatitis, there is a possibility that patients with Cushing's disease might be more prone to acute pancreatitis following propofol administration.",Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since recent studies have reported no negative interactions with concurrent use, we here report three cases (one case of a prolonged seizure, a serotonin syndrome and a focal seizure) of severe lithium-induced side effects while patients underwent ECT without complications and lithium serum levels were still subtherapeutic.",Partial seizures
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CD20-negative T-cell-rich B-cell lymphoma as a progression of a nodular lymphocyte-predominant Hodgkin's lymphoma treated with rituximab: a molecular analysis using laser capture microdissection.,B-cell lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Recently, CD20-negative tumors have been described after Rituximab therapy.",B-cell lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 51-year old physically fit woman experienced angio-oedema and hypotensive shock after irbesartan ingestion requiring noradrenaline infusion.,angio-OOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, our report is one of the first on shock and angio-oedema from irbesartan.",angio-OOedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She died within six weeks of developing congestive heart failure coupled with liver failure due to haemosiderosis despite regular use of desferrioxamine.,Cardiac failure congestive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transfusion haemosiderosis inspite of regular use of desferrioxamine: case report.,Haemochromatosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"One of the side-effects of intravitreal triamcinolone is the development of cataract, and it is known that cataract extraction can exacerbate macular degeneration.",Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe loss of vision after removal of cataract caused by intravitreal triamcinolone in combination with photodynamic therapy for exudative age-related macular degeneration.,Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rhabdomyolysis caused by tocolysis with oral ritodrine hydrochloride in a pregnant patient with myotonic dystrophy.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rhabdomyolysis has been recognized as a complication of tocolytic therapy with ritodrine hydrochloride.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report here a rare case of ritodrine-hydrochloride-induced rhabdomyolysis in a pregnant patient with myotonic dystrophy.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute myocardial ischemia following accidental intravenous administration of epinephrine in high concentration.,Myocardial ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a case of acute epinephrine toxicity resulting in acute myocardial ischemia in a young boy with combined variable immunodeficiency syndrome who developed severe allergic reaction to intravenous immunoglobulin, and was subsequently given epinephrine by mistake intravenously rather than subcutaneously.",Myocardial ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Polysomnographic and pharmacokinetic findings in levodopa-induced augmentation of restless legs syndrome.,Restless legs syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Videopolysomnographic and pharmacokinetic studies with monitoring of plasma levodopa levels demonstrated marked motor hyperactivity during augmentation, with anarchic discharges of motor unit potentials, tonic grouped discharges and flexor spasms, associated with painful dysesthesia.",Muscle contractions involuntary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The major side effect of infliximab is infection.,Infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report describes a probable case of infliximab-induced membranous nephropathy.,Glomerulonephritis membranous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Linezolid-induced dyserythropoiesis: chloramphenicol toxicity revisited.,Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report here two cases of dyserythropoietic anaemia associated with long-term linezolid use that share striking similarities to chloramphenicol-associated myelotoxicity.,Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A selective association between fluoxetine and extensive, prominent eye movements in nonrapid eye movement (NREM) sleep was detected, utilizing Fisher's exact one-tailed statistic (p less than 0.00001 for each comparison).",Sleep disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition, a 31-year-old man with obsessive-compulsive disorder developed RBD soon after starting fluoxetine therapy, which persisted at PSG study 19 months after fluoxetine discontinuation.",Sleep disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder.,Sleep disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because of serious side effects of an increase in the QT interval causing torsades de pointes, dofetilide must be initiated with close monitoring of the QT interval in an inpatient setting.",Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Marked QT prolongation and torsades de pointes secondary to acute ischemia in an elderly man taking dofetilide for atrial fibrillation: a cautionary tale.,Myocardial ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report marked QT prolongation and torsades de pointes in a setting of flash pulmonary edema resulting from acute myocardial ischemia in a patient who was being treated with dofetilide for atrial fibrillation.,Myocardial ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prominent positive U waves appearing with high-dose intravenous phenylephrine.,Electrocardiogram abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"While on a maximal dose of phenylephrine she developed prominent positive U waves, which disappeared with the cessation of the drug.",Electrocardiogram abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatoxicity is a rare complication of SRL therapy and may be connected with some diagnostic and/or therapeutic problems.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sirolimus-associated hepatotoxicity in the kidney graft recipient.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The aim of our paper was to describe hepatotoxicity of sirolimus (SRL) in a kidney graft recipient.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE REPORT: We present a case of a 28-yr-old male who developed a severe case of nephrotic syndrome while being treated for relapsing/remitting Multiple Sclerosis (RRMS) with weekly injections of interferon beta 1a.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nephrotic syndrome in a multiple sclerosis patient treated with interferon beta 1a.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,SUBSEQUENT COURSE: The nephrosis resolved almost completely once the interferon was stopped and after immunosuppressive treatment.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This latest (third) report suggests that the safety profile should be reexamined and at least raises the question of potential renal toxicity of interferons in MS.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Capecitabine-induced multifocal leukoencephalopathy: a report of five cases.,Progressive multifocal leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report five additional cases of capecitabine-induced multifocal leukoencephalopathy.,Progressive multifocal leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 56-year-old white woman with a diagnosis of reactive depression developed severe UI after a 30 days' treatment with venlafaxine 75 mg/day.,Urinary Incontinence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report a case of urinary incontinence (UI) that occurred in a woman after administration of venlafaxine.,Urinary Incontinence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Venlafaxine-induced urinary incontinence resolved after switching to sertraline.,Urinary Incontinence
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diagnosis of hypothyroidism during treatment can be difficult because of the common side effects of alpha interferon.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sustained hypothyroidism induced by recombinant alpha interferon in patients with chronic hepatitis C.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thyroid dysfunction has been reported in patients with malignant disease treated with recombinant alpha interferon.,Thyroid disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two cases of hypothyroidism in patients with chronic hepatitis C treated with recombinant alpha interferon are reported.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atrial fibrillation after vardenafil therapy.,Atrial fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case admitted with a first-detected, symptomatic paroxysmal atrial fibrillation in a healthy patient after self-medication with vardenafil.",Atrial fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of infection with Mycobacterium abscessus in a 67-year-old woman receiving infliximab as a component of her therapy for RA.,Mycobacterium abscessus infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DIAGNOSIS: Interferon alpha-2b-induced cardiomyopathy.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible cardiomyopathy caused by administration of interferon alpha.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,In this case senna was likely the cause of a subacute cholestatic hepatitis exemplifying again the potential role of herbal related liver injury.,Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation.,Hepatitis cholestatic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of senna-induced cholestatic hepatitis which was not diagnosed at presentation.,Hepatitis cholestatic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Based on the history and clinical features, a diagnosis of insulin-induced lipohypertrophy was made.",Lipohypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Insulin-induced lipohypertrophy: report of a case with histopathology.,Lipohypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thus, the possible in vivo effects of insulin on adipocytes were clearly observed in this case of insulin-induced lipohypertrophy.",Lipohypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first report of insulin-induced lipohypertrophy with detailed histological examinations.",Lipohypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 7-year-old girl developed diabetes mellitus and exocrine pancreatic insufficiency after 3.5 years of almost continuous treatment with azathioprine and/or prednisone for idiopathic auto-immune haemolytic anaemia.,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An objective causality assessment suggests that the JHR in our patient was probably related to penicillin.,Jarisch-Herxheimer reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE SUMMARY: A 45-year-old HIV-positive man (CD4+ count 450 cells/mm(3) and history of AIDS-defining illness) presented with JHR after an initial intravenous dose of penicillin G for presumed neurosyphilis.,Jarisch-Herxheimer reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Penicillin-induced Jarisch-Herxheimer reaction.,Jarisch-Herxheimer reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient described feeling cold with worsening headache and chills approximately one hour after infusion of the first dose of penicillin.,Chills
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute respiratory distress syndrome after rituximab infusion.,Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"ARDS has been associated with the administration of other monoclonal antibodies, such as infliximab, gemtuzumab ozogamicin, and OKT3 and is believed to be directly mediated by release of proinflammatory cytokines.",Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"ARDS is rarely associated with rituximab infusion for lympho-proliferative disorders, but it should be considered by those administering rituximab, especially when a patient develops severe pulmonary symptoms soon after infusion.",Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Dyspnea, hypoxemia, and pleuritic chest pain occurred within 24 hours of rituximab administration, and there was no other apparent explanation.",Dyspnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Progressive hypoxemia mandated endotracheal intubation 1 week after rituximab administration and led to death 4 weeks after admission.,Hypoxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a 43-year-old man with ITP refractory to steroids and intravenous immunoglobulin who developed acute respiratory distress syndrome (ARDS) after a single infusion of rituximab.,Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Symptomatic hypocalcaemia and renal impairment associated with bisphosphonate treatment in patients with multiple myeloma.,Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report three cases of severe hypocalcaemia associated with i.v. bisphosphonate treatment in patients with multiple myeloma.,Hypocalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gemcitabine-related radiation recall in a patient with pancreatic cancer.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gemcitabine should be added to the list of drugs known to cause radiation recall.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Radiation recall from gemcitabine is rare, but can potentially arise in any site that has been previously irradiated.",Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Radiation recall related to gemcitabine has been reported in lung and breast cancer.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient with inoperable pancreatic cancer who developed gastrointestinal bleeding secondary to radiation-recall related to gemcitabine and review literature.,Gastrointestinal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We suggest discontinuing gemcitabine if radiation recall is observed.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 17-year-old boy with acute lymphoblastic leukemia developed acute renal failure within 48 h of an intravenous high-dose methotrexate (5 g/m2) infusion.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,High-dose methotrexate-associated acute renal failure may be an avoidable complication.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Methotrexate-associated nephropathy is a rare complication in pediatric oncology, and a review of the literature suggests that exposure to nephrotoxic agents may be a significant but perhaps underrecognized risk factor for its development.",Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Massive prolapse of the urethral mucosa following periurethral injection of calcium hydroxylapatite for stress urinary incontinence.,Urethral prolapse
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors present a case report of a granulomatous reaction leading to urethral prolapse, 3 months after the transurethral injection of calcium hydroxylapatite.",Granuloma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first granulomatous reaction described after calcium hydroxylapatite injection.",Granuloma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARY: A 57-year-old female with cardiomyopathy and ""sulfa"" (trimethoprim/sulfamethoxazole) allergy documented as pancreatitis presented with symptoms consistent with pancreatitis after use of furosemide.",Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition, while cases of loop diuretic-induced pancreatitis, including furosemide, have been published, the allergic manifestations with both sulfonamide antibiotics and non-antibiotics in our patient suggest possible cross-reactivity between these 2 drug classes.",Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Torsemide appears to also be a part of a long list of agents that can cause pancreatitis.,Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Heparin-induced thrombocytopenia complicated with massive thrombosis of the inferior vena cava after filter placement.,Vena cava Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On the 3rd day, an inferior vena cava (IVC) filter was placed with a heparin flush, after which massive IVC thrombosis developed.",Vena cava Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient was positive for antibody against complexes of heparin and platelet factor 4, and was diagnosed as heparin-induced thrombocytopenia with thrombosis syndrome (HITTS).",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When thrombosis develops during heparin treatment, it is important to suspect HITTs and to assay for the associated antibodies, regardless of the actual platelet count.",Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After gastric-outlet obstruction was recognized in several infants who received prostaglandin E1, we studied the association between the drug and this complication.",Obstruction gastric
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The administration of prostaglandin E1 to neonates can cause gastric-outlet obstruction due to antral hyperplasia.,Gastric mucosal hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Moreover, treatment with immunosuppressive drugs such as cyclosporine, cisplatin, tacrolimus, and interferon-alpha can induce a condition resembling RPLS.",Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible posterior leukoencephalopathy syndrome in systemic lupus erythematosus with thrombocytopenia treated with cyclosporine.,Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of a young woman with SLE and thrombocytopenia, who developed severe perspiration, headache, and seizure after receiving cyclosporine.",Headache
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe a case of exacerbated mania potentially related to an interaction between lopinavir/ritonavir and valproic acid (VPA) and propose a mechanism of action for this interaction.,Mania
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Possible interaction between lopinavir/ritonavir and valproic Acid exacerbates bipolar disorder.,Bipolar disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After intravitreal injection of triamcinolone acetonide, cataract may rapidly develop in eyes that have been intensively treated, topically and systemically, by corticosteroids for several years.",Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Arthritis and bursitis in multiple sclerosis patients treated with interferon-beta.,Arthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Our literature review revealed an additional six cases of onset of inflammatory arthritis in MS patients receiving IFN-beta.,Arthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The first patient developed a monoarthritis 2 weeks after initiation of IFN-beta, which persisted during the 14 months of therapy and resolved with discontinuation of the medication.",Arthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present the cases of two female patients diagnosed with relapsing-remitting multiple sclerosis (RRMS) who developed inflammatory musculoskeletal manifestations, following IFN-beta therapy.",Inflammation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Trimethoprim-sulfamethoxazole-induced aseptic meningitis.,Meningitis aseptic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a 46-year-old African-American man with AIDS who was admitted on two different occasions within three weeks for signs and symptoms of meningitis after using trimethoprim/sulfamethoxazole (TMP/SMX).,Meningitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We reviewed the literature in an attempt to characterize the pattern and predictors of TMP/SMX-induced aseptic meningitis.,Meningitis aseptic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this paper, we report a patient with primary anti-phospholipid syndrome treated by corticosteroid, who developed disseminated nocardiosis.",Nocardiosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chloroquine-induced bilateral ptosis.,Eyelid ptosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ptosis occurring 24 h after chloroquine therapy, with full recovery 48 h after cessation of chloroquine, has not been described previously.",Ptosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report describes a case of bilateral ptosis induced by chloroquine.,Eyelid ptosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DESIGN: We reviewed the medical records of four patients, who were seen by us between July 2000 and February 2004 for sudden onset of a central neurological syndrome within days of intrathecal MTX.",Immune-mediated neurological disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diffusion-weighted MRI correlates of subacute methotrexate-related neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVES: A delayed stroke-like leukoencephalopathy has been observed in patients receiving methotrexate (MTX) for childhood leukemia.,Cerebrovascular accident-like leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Our objective is to present a retrospective analysis of the DWI findings in four patients who suffered subacute neurotoxicity after intrathecal MTX.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is a rare case of ARDS associated with lithium intoxication.,Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: The present findings suggest that: (i) amantadine probably exerts its anti-dyskinetic effect by acting on the ""indirect"" pathway; (ii) the pathophysiological mechanisms of subthalamotomy induced dyskinesias may differ from those involved in L-dopa induced dyskinesias; (iii) dyskinesias induced by STN surgery resolve spontaneously as compensatory mechanisms develop.",Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Prior to surgery, levodopa induced dyskinesia had improved (< or = 50%) under treatment with amantadine (400 mg/day, po) in all three patients.",Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A combination of behavioural and cognitive adverse effects is illustrated in this case report of a recurrent triazolam-induced eating disorder.,Eating disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Triazolam-induced nocturnal bingeing with amnesia.,Amnesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although interferon gamma has been implicated in the pathogenesis of sarcoidosis, only a few cases of sarcoidosis associated with interferon alpha therapy have been reported.",Sarcoidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of sarcoidosis during interferon alpha 2b and ribavirin combination therapy for chronic hepatitis C--a case report and review of the literature.,Sarcoidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case with chronic hepatitis C (CHC) who developed sarcoidosis after the treatment by interferon alpha and ribavirin.,Sarcoidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We suggest that sarcoidosis may develop in chronic hepatitis C patients during interferon alpha and/or ribavirin treatment, and diagnostic tests for this adverse effect should be performed during the follow-ups.",Sarcoidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neutropenic colitis during standard dose combination chemotherapy with nedaplatin and irinotecan for testicular cancer.,Neutropenic colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this paper, we report a case of severe hypercalcemia of immobilization in a 40-year-old hemodialyzed woman treated by cinacalcet HCl for a severe HPTH-II (PTH>1,000 pg/mL).",Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here, we present a case of sirolimus-associated interstitial pneumonitis in a cardiac transplant recipient that resolved completely with withdrawal of the drug and treatment with corticosteroids.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible sirolimus-associated pneumonitis after heart transplantation.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two cases of sirolimus-associated pneumonitis have been reported after cardiac transplantation.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An objective causality assessment by use of the Naranjo probability scale revealed that NCSE due to ifosfamide was probable.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE SUMMARIES: Two patients who received ifosfamide-containing chemotherapy developed NCSE.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Among the many presentations of ifosfamide neurotoxicity, clinicians should consider NCSE as a possible explanation for changes in consciousness in a patient receiving this agent.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"NCSE, an epileptic disorder in which typical convulsive activity is absent, has previously been reported in only 4 patients receiving ifosfamide.",Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nonconvulsive status epilepticus due to ifosfamide.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report 2 cases of nonconvulsive status epilepticus (NCSE) following infusion of ifosfamide.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of intraoperative gelatine-induced anaphylaxis whose diagnosis was delayed as the use of gelatine during surgical procedures was omitted for two times in patient's medical records.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cutaneous mycobacterial infection post intravesical BCG installation.,Mycobacterial infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disseminated tuberculous lesions post intravesical BCG therapy are rare but need to be identified and treated quickly.,Disseminated tuberculosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Some patients develop hypersensitivity rash in response to HCQ.,Hypersensitivity Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Administration of sumatriptan in subarachnoid haemorrhage (SAH) patients, misdiagnosed as migraine patients, may induce symptomatic cerebral vasospasm with potentially dangerous consequences.",Cerebral vasoconstriction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"METHOD: We describe two patients who presented with diabetic ketoacidosis after treatment with quetiapine and risperidone, respectively.",Diabetic ketoacidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.",Lymphocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first case of TMP-SMX-induced hypersensitivity syndrome associated with the reactivation of a latent viral infection.,Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Trimethoprim-sulfamethoxazole-induced hypersensitivity syndrome associated with reactivation of human herpesvirus-6.,Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report a case of severe corticosteroid-induced glaucoma after intravitreal injection of triamcinolone acetate in a 34-year-old man without a history of glaucoma.,Glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: A 34-year-old man acquired visual field defects and severe vision loss in both eyes after intravitreal injection of triamcinolone for diabetic macular edema.,severe vision loss
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe steroid-induced glaucoma following intravitreal injection of triamcinolone acetonide.,Glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This treatment has the potential to cause severe vision loss as a result of intractable corticosteroid-induced glaucoma.,Glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Autoimmune thyroid disease is a common side-effect of interferon-alpha (IFN-alpha) treatment of viral hepatitis C.,Autoimmune thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Destructive thyrotoxicosis appeared 4-6 months after starting IFN-alpha, followed by Graves' hyperthyroidism within 8 to 11 months.",Graves' disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Hence, hyperthyroidism induced by IFN-alpha could correspond to the first phase of silent thyroiditis, to Graves' disease or to the succession of both.",Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interferon-alpha-induced hyperthyroidism: a three-stage evolution from silent thyroiditis towards Graves' disease.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We have described three patients with hepatitis C for whom IFN-alpha and ribavirin were prescribed and who developed two successive phases of silent thyroiditis followed by hyperthryroidism relapse due to Graves' disease.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Dipyrone, also known as metamizole, is an analgesic and antipyretic drug that was banned by the United States Food and Drug Administration because of its association with agranulocytosis.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dipyrone-induced granulocytopenia: a case for awareness.,Granulocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient who developed granulocytopenia and fever after taking dipyrone and discuss the available literature.,Granulocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Herein, we describe 2 patients who developed unusual CD8+ cutaneous lymphoproliferative disorders after treatment with efalizumab and infliximab.",Lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines.",Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case underscores problems in clinical management with sulfadiazine hypersensitivity, potential immunosuppression from corticosteroids and selection of medications for recurrences of toxoplasmic chorioretinitis.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fatal lung fibrosis caused by paclitaxel toxicity has not been reported In this report, we describe the case of a 62-year-old woman who received six cycles of paclitaxel and carboplatin as combination chemotherapy for advanced ovarian cancer.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal pulmonary fibrosis induced by paclitaxel: a case report and review of the literature.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Physicians should keep in mind that taxanes such as paclitaxel have the potential to cause pneumonitis and lung fibrosis.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary fibrosis is a complication of paclitaxel therapy that may occur despite treatments with corticosteroids.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this case report, we have described a patient with Crohn's disease who developed subfulminant hepatitis B after the fourth infusion of infliximab due to an unrecognized HBs-antigen carrier state.",Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Subfulminant hepatitis B after infliximab in Crohn's disease: need for HBV-screening?,Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute unilateral total visual loss after retrogasserian phenol injection for the treatment of trigeminal neuralgia: a case report.,Sudden visual loss
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The visual loss in this patient seems to result from phenol neurotoxicity rather than mechanical compression of the intraorbital optic nerve.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 78-year-old man who had acute unilateral total visual loss after retrogasserian phenol injection for the treatment of trigeminal neuralgia.,Sudden visual loss
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug induced liver injury secondary to interferon-beta (IFN-beta) in multiple sclerosis.,Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Grade 3 hepatotoxicity (AST and ALT > 5 to 20 upper limit normal) or higher has been observed in as many as 1.4% of MS patients on IFN beta.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Post marketing studies of Interferon-beta (IFN beta) therapy in multiple sclerosis (MS) have demonstrated surprisingly high rates of hepatotoxicity.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report three cases of IFN beta induced hepatitis in MS and discuss the pathology findings and possible mechanisms of drug-induced liver injury.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 55-year-old woman presented an episode of acute urticaria and labial angioedema 60 minutes after ingesting 500 mg of cloxacillin for a skin abscess.,Urticaria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Allergy to cloxacillin with normal tolerance to amoxicillin and cefuroxime.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Several hypersensitivity reactions to cloxacillin have been reported, although IgE-mediated allergic reactions to the drug are rare and there is little information about possible tolerance to other semisynthetic penicillins or cephalosporins in patients with cloxacillin allergy.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiac toxicity related to BCNU has not been described well.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myocardial ischemia associated with high-dose carmustine infusion.,Myocardial ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three patients are reported without a history of angina pectoris who had clinical and electrocardiographic evidence of myocardial ischemia during and immediately after BCNU infusion.,Myocardial ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Adverse reaction in a patient with aspirin-induced asthma treated with zafirlukast.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of hypereosinophilia related to zafirlukast therapy.,Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Shortly after chemotherapy and an injection of pegfilgrastim, the patient developed poorly defined, rapidly progressive erythema, edema, and pain in his right forearm.",Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A few recent individual case reports have suggested that a myasthenic syndrome may be associated with statin treatment, but this association is not well described.",Myasthenic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Statin-associated myasthenia gravis: report of 4 cases and review of the literature.,Myasthenia gravis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report 4 patients who developed symptoms of myasthenia gravis within 2 weeks of starting treatment with a statin drug.,Myasthenia gravis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reactivation of cytomegalovirus probably followed the treatment of Wegener's granulomatosis with corticosteroids and azathioprine.,Cytomegalovirus infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After excluding other causes of long QT syndrome, the HCQ was suspected as the cause of her ventricular tachycardia.",Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chronic hydroxychloroquine use associated with QT prolongation and refractory ventricular arrhythmia.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: The chronic use of HCQ for rheumatic diseases, or as an anti-malarial drug, should be balanced against the risk of developing potentially lethal cardiac arrhythmias.",Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of chronic use of HCQ associated with torsade de pointes.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The increasing prevalence of Type 2 diabetes and its treatment with metformin might result in more cases of lactic acidosis.,Lactic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe acidosis in patients taking metformin--rapid reversal and survival despite high APACHE score.,Acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case report: lack of control of diabetes and weight gain in a patient on initiation and rechallenge of therapy with olanzapine.,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The following is a case report analysis intended to draw attention to the need for better care coordination by describing the observed relationship of olanzapine to metabolic changes manifested as uncontrolled diabetes mellitus and weight gain.,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient was enrolled in a weight-loss clinic, and his diabetes medications were adjusted.Subsequently, olanzapine was discontinued because of weight gain and uncontrolled diabetes.",Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report a case of traumatic flap dehiscence and Enterobacter keratitis 34 months after LASIK.,Keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Traumatic late flap dehiscence and Enterobacter keratitis following LASIK.,Keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a lung cancer patient with bronquiloalveolar carcinoma (BAC) presenting with BOOP after chemotherapy with docetaxel and gemcitabine producing severe respiratory insufficiency, and simulating a progression of the tumor.",Organising pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 65-year-old man on warfarin therapy with a sudden spontaneous onset of sub-conjunctival haematoma associated with bloody tears was assessed in the clinic following a referral from an optometrist.,Epistaxis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An unusual presentation of spontaneous sub-conjunctival haematoma in a patient receiving warfarin.,Conjunctival haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Due to discomfort, diplopia and lagophthalmos, the haematoma necessitated suspension of warfarin therapy and a surgical evacuation.",Diplopia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The sub-conjunctival haematoma in a patient receiving warfarin can pose a significant management challenge.,Conjunctival haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Angioedema and maculopapular eruptions associated with carbamazepine administration.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Angioedema, a rare side effect of carbamazepine, involves vascular leakage in dermis and subcutis mediated by immunoglobulin E and/or bradykinins.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cutaneous eruptions occur in 3% of individuals administered carbamazepine.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Cutaneous rashes and eruptions can be caused by many medications, including carbamazepine.",Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a 27-year-old Indian woman who developed maculopapular rash and angioedema secondary to carbamazepine administration.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe adenovirus pneumonia (AVP) following infliximab infusion for the treatment of Crohn's disease.,Pneumonia adenoviral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of severe AVP three weeks following the administration of infliximab for the treatment of Crohn's disease (CD).,Pneumonia adenoviral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,First case of ivermectin-induced severe hepatitis.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first case of ivermectin-induced severe liver disease published in the literature.",Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a 20-year-old woman originally from Cameroon who was infected by the L. loa parasite and developed severe hepatitis, identified 1 month after a single dose of ivermectin.",Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE REPORT: We hereby report a case of radiation recall dermatitis and myositis occurring on gemcitabine monotherapy, five months after completing chemoradiation for locally advanced pancreatic cancer.",Myositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: This is the second case report that describes gemcitabine-induced radiation recall in rectus abdominus muscles after gemcitabine-based radiation therapy.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gemcitabine-induced rectus abdominus radiation recall.,Recall phenomenon
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sporadic rippling muscle disease unmasked by simvastatin.,Rippling muscle disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 53-year-old-man who developed rippling muscle disease (RMD) 2 months after starting simvastatin therapy for hypercholesterolemia.,Rippling muscle disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute coronary syndrome induced by capecitabine therapy.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case highlights the possible development of acute coronary syndrome as a side effect of Capecitabine therapy.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acute severe intoxication with carbamazepine is associated with seizures, coma and respiratory depression.",Coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After rechallenge with monotherapy pegvisomant, however, the hepatic enzyme disturbances reappeared within a few weeks, indicating that most likely pegvisomant alone and not the long-acting somatostatin analog or the combination of these two drugs was responsible for this case of drug-induced hepatitis.",Hepatic enzyme increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug-induced hepatitis in an acromegalic patient during combined treatment with pegvisomant and octreotide long-acting repeatable attributed to the use of pegvisomant.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The hepatic enzyme disturbances normalized after discontinuation of pegvisomant.,Hepatic enzyme increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on a patient with acromegaly who developed severe drug-induced hepatitis during combined treatment with the long-acting somatostatin-analog octreotide and the GH receptor antagonist pegvisomant.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Amphotericin B (AmB) is effective, but its use is limited by toxicity: renal impairment, anaemia, fever, malaise, and hypokalaemia are common.",Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DIAGNOSIS: Severe temozolomide-induced immunosuppression, exacerbated by corticosteroids, with profound T-cell lymphocytopenia and simultaneous opportunistic infections with Pneumocystis jiroveci pneumonia, brain abscess with Listeria monocytogenes, and cutaneous Kaposi's sarcoma.",Brain abscess
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after temozolomide.",Kaposi's sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: Topiramate-induced angle-closure glaucoma (TiACG) is believed to be related to its sulfonamide moiety.,Angle closure glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rapid resolution of topiramate-induced angle-closure glaucoma with methylprednisolone and mannitol.,Angle closure glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Spontaneous splenic infarction associated with sumatriptan use.,Splenic infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Though they are generally considered safe, there have been a few reports of myocardial infarction and stroke associated with triptan use.",Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient who developed spontaneous splenic infarction after the use of sumatriptan for the treatment of migraine headache.,Splenic infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute myocardial infarction during high-dose methylprednisolone therapy for Graves' ophthalmopathy.,Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Except hypothyroidism after radioiodine treatment (euthyroid under substitutional therapy), she suffered from no other diseases.",Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here we present the case of a woman who received high doses of methylprednisolone (1 g iv daily) for active Graves' ophthalmopathy, and developed severe hypertension followed by myocardial infarction on the fifth day of treatment.",Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We conclude that myocardial infarction may develop in patients treated with high-dose glucocorticoids for Graves' ophthalmopathy, and increased blood pressure may herald this complication.",Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Presented is a case story of a woman with classical rheumatoid arthritis, who during introduction of sulphasalazine (SASP) therapy developed a severe and lasting psoriasis-like skin reaction.",Psoriasis-like skin reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Psoriasis-like skin reaction in a patient with rheumatoid arthritis after sulphasalazine therapy.,Psoriasis-like skin reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Five days after the fourth dose of vincristine, she presented with bilateral ptosis.",Eyelid ptosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Vincristine induced cranial polyneuropathy.,Cranial nerve disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a 5-year-old girl showed recovery of vincristine induced cranial polyneuropathy with pyridoxine and pyridostigmine treatment.,Cranial nerve disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acute generalized exanthematous pustulosis caused by morphine, confirmed by positive patch test and lymphocyte transformation test.",Acute generalised exanthematous pustulosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Morphine, an opium alkaloid, frequently causes side effects such as hyperhidrosis and facial flushing, but serious cutaneous adverse drug reactions are seldom observed.",Flushing
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of a man treated with an EGFR-inhibitor (erlotinib) for a cell lung cancer who developed skin manifestations localized in an uncommon area and with an atypical evolution.,Dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Olanzapine-associated neuroleptic malignant syndrome.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Allergic contact angioedema to benzoyl peroxide.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Factors that suggested an association between the severe angioedematous reaction and BP topical application include the strong reaction to BP in the patch-test, the temporal relationship, the complete resolution of symptoms after the drug was withdrawn and the absence of other identified explanations.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 35-year-old woman presented with neurotoxicity correlated to an i.v. regimen of 5-fluorouracil as episodes of acute confusional state and abnormalities of symmetrically restricted diffusion in the periventricular white matter and corpus callosum.,Confusional state
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible findings of restricted diffusion in 5-fluorouracil neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present the case of a 58-year-old woman who ingested more than 35 g of caffeine in a suicide attempt.,Suicide attempt
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome.,Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe dapsone hypersensitivity syndrome.,Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a 21-year-old female patient with dapsone hypersensitivity syndrome.,Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylaxis to intrathecal diamorphine.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We believe this is the first report of intrathecal diamorphine causing anaphylaxis.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We highlight two instances of systemic allergic reaction, and discuss the potential side effects of local aprotinin injections in the orthopaedic setting as well as the evidence base for its use.",Drug hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"METHOD: Case analysis of a poly-drug overdose (venlafaxine, topiramate, divalproex sodium, risperidone, and carbamazepine) presenting with mixed SS/NMS features and whose clinical management suggests a practical algorithm for treatment of undifferentiated SS/NMS in critical care settings.",Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fever and maculopapular rashes appeared at 10 days after phenytoin initiation, and then the drug was discontinued.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Localized purpura associated with lamotrigine.,Purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case study is the second report of localized purpura after prolonged lamotrigine treatment suggesting this may be an atypical lamotrigine-induced drug reaction.,Purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report describes a 13-year-old female with a right frontal high-grade glioma and complex partial seizures who developed localized purpura after 23 months of lamotrigine monotherapy.,Purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure during lisinopril and losartan therapy for proteinuria.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report describes a case of acute compromise of renal function associated with hypotension in a 7-year-old boy treated with the ACE inhibitor lisinopril and the ARB losartan.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bronchiolitis obliterans with organizing pneumonia after rituximab therapy for non-Hodgkin's lymphoma.,Organising pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Moreover, these findings suggest that the incidence of BOOP following rituximab therapy may be higher than has been previously appreciated.",Organising pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This is the first reported case of BOOP associated with single-agent rituximab, and along with two other patients we describe, as well as two prior reports of BOOP in NHL patients receiving rituximab-based combinations, strengthens the possibility of a causal relationship.",Organising pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a case of an NHL patient who received rituximab and developed symptomatic, biopsy-proven multinodular bronchiolitis obliterans with organizing pneumonia (BOOP).",Organising pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lower extremity arterial thrombosis following sonographically guided thrombin injection of a femoral pseudoaneurysm.,Arterial thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Native arterial thrombosis, though recognized as a severe complication of thrombin injection, has not been well described in the literature.",Arterial thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of successful surgical management of arterial thrombosis after percutaneous thrombin injection of a femoral artery pseudoaneurysm in a 69-year-old woman.,Arterial thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A small number of oxaliplatin-related hemolytic and/or thrombocytopenic reactions have been reported.,Haemolytic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hemolytic uremic syndrome following the infusion of oxaliplatin: case report.,Hemolytic uremic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a case of hemolytic-uremic syndrome that developed during the 4th cycle of combination chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"First, a review of the literature produced 41 anecdotic cases of neutropenia or agranulocytosis during treatment with olanzapine (Zyprexa) reported in a total of 24 publications.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neutropenia and agranulocytosis are risks known to occur with phenothiazines and clozapine.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Second, we report a case of neutropenia, which proved to be fatal in a schizophrenia patient receiving olanzapine and thiazide.",Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thus any case of severe neutropenia occurring in a patient receiving olanzapine is alarming to clinicians.,Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a depressive patient who developed mild parkinsonian signs and camptocormia after the introduction of olanzapine.,Camptocormia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Five months after initiating mirtazapine therapy, she developed symptomatic hyponatremia.",Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this case, unlike those previously reported, hyponatremia recurred 5 months after switching from citalopram to mirtazapine, which is believed to be a safe antidepressant.",Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Recurrent hyponatremia associated with citalopram and mirtazapine.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 43-year-old woman with multiple sclerosis (MS) had nephrotic syndrome 21 months after starting treatment with interferon (IFN)-beta-1b (subcutaneous administration).,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because nephrotic syndrome may be induced by IFN therapy, the IFN was stopped.",Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nephrotic syndrome associated with interferon-beta-1b therapy for multiple sclerosis.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Though proteinuria and nephrotic syndrome is a rare adverse effect of IFN-beta-1b therapy, physicians treating MS patients with this agent should pay careful attention to new clinical symptoms and laboratory findings.",Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 70-year-old man was admitted to our hospital because of dyspnea after taking an antihistaminic agent (homochlorcyclizine hydrochloride) for itching.,Dyspnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acute eosinophilic pneumonia caused by calcium stearate, an additive agent for an oral antihistaminic medication.",Eosinophilic pneumonia acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Therefore, we concluded that this patient's pulmonary disease was caused by calcium stearate, an additive for an antihistaminic drug.",Autoimmune lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Scleritis complicating zoledronic acid infusion.,Scleritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of severe unilateral posterior scleritis associated with zoledronic acid administration that was recognized and treated in a timely manner.,Scleritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Late lethal hepatitis B virus reactivation after rituximab treatment of low-grade cutaneous B-cell lymphoma.,Hepatitis B reactivation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Several such HBV reactivations were reported after combined rituximab and multiagent chemotherapy for B-cell lymphomas.,Hepatitis B reactivation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first case of HBV reactivation occurring during the year following rituximab monotherapy in the absence of any other immunosuppressive factor.,Hepatitis B reactivation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is a case report of fatal cryptococcal meningitis in a child with systemic lupus erythematosus being treated with prednisolone and azathioprine.,Meningitis cryptococcal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An intertrigo-like eruption from pegylated liposomal doxorubicin.,Intertrigo
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This eruption appears to be a distinct cutaneous toxicity of PLD.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a 60-year-old woman who developed erythema and erosions in the axilla and groin while on PLD for breast cancer.,Skin erosion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Herein is reported an unusual case of coexistent warfarin-induced skin necrosis and heparin-induced thrombocytopenia following mitral valve replacement for thromboembolic phenomena associated with marantic endocarditis and bronchial adenocarcinoma.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Warfarin-induced skin necrosis and heparin-induced thrombocytopenia following mitral valve replacement for marantic endocarditis.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Exposure of the fetus to indomethacin by administration of the drug to the mother may cause many side effects, including premature closure of the ductus arteriosus.",Ductus arteriosus premature closure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypoxia is a predisposing factor for premature ductal closure and often occurs after maternal indomethacin therapy.,Hypoxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Premature closure of the ductus arteriosus: variable response among monozygotic twins after in utero exposure to indomethacin.,Ductus arteriosus premature closure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This selective closure of the ductus arteriosus suggests that the affected twin was predisposed to hypoxia and thus was more susceptible to ductal closure in response to indomethacin exposure.,Ductus arteriosus premature closure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: These cases suggest that moxifloxacin may interfere with the healing of corneal ulcers.,Ulcerative keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Both cases presented here describe corneal ulcers that persisted and showed signs of worsening during weeks of frequent topical dosing with moxifloxacin.,Ulcerative keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe corneal toxicity after topical fluoroquinolone therapy: report of two cases.,Corneal toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute generalized exanthematous pustulosis induced by nimesulide.,Acute Acute generalised exanthematous pustulosisatous pustulosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of acute generalized exanthematous pustulosis (AGEP) in a 50-year-old woman that was attributed to the ingestion of nimesulide.,acute Acute generalised exanthematous pustulosisatous pustulosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: Amphotericin B deoxycholate has been reported to produce significant cardiac toxicity, with ventricular arrhythmias and bradycardia reported in overdoses in children and in adults with preexisting cardiac disease, even when administered in conventional dosages and infusion rates.",Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the clinical course of a woman with cryptococcal meningitis and no previous cardiac disease who developed a fatal cardiac arrhythmia after an acute overdose of amphotericin B and to review its toxicity.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Use of the Naranjo probability scale indicated a highly probable relationship between the observed cardiac toxicity and amphotericin B deoxycholate therapy in this patient.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors describe a case of valvular heart disease in a 48-year-old woman receiving benfluorex (150 mg t.i.d. for 8 years) and leading to surgical mitral valve replacement.,Cardiac valve disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Valvular heart disease in a patient taking benfluorex.,Cardiac valve disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The main side-effects of Lp-TAE combined with HT were low-grade fever, localized pain, myelo-suppression and liver dysfunction, but these were transient and eventually disappeared.",Hepatic function abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tacrolimus-induced HUS: an unusual cause of acute renal failure in nephrotic syndrome.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thus, tacrolimus-induced HUS is a rare cause of ARF in nephrotic syndrome.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Liver transplantation for fulminant hepatitis related to nevirapine therapy.,Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation.,Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cholelithiasis and thrombosis of the central retinal vein in a renal transplant recipient treated with cyclosporin.,Cholelithiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this report, a patient who had undergone a renal transplantation as a result of malignant hypertension, and who was on immunosuppressive therapy consisting of cyclosporin, prednisone and azathioprine, developed thrombosis of the central retinal vein 5 years following the transplantation.",Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The use of cyclosporin has been associated with the development of cholelithiasis in transplant recipients.,Cholelithiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity induced by cyproterone acetate: a report of three cases.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three male patients aged 78-83 years are presented, in whom severe hepatotoxic reactions emerged after CPA administration.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE PRESENTATION: Three cases of Leishmania infantum leishmaniasis in corticosteroid (CS)-treated patients are reported: an isolated lingual leishmaniasis in a farmer treated with CS for asthma, a severe visceral leishmaniasis associated with cutaneous lesions in a woman with myasthenia gravis, and a visceral involvement after cutaneous leishmaniasis in a man receiving CS.",Cutaneous leishmaniasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Leishmania infantum leishmaniasis in corticosteroid--treated patients.,Visceral leishmaniasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, an association of Ritalin with glaucoma has been reported.",Glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Large dose of methylphenidate may cause cataract and glaucoma.,Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methylphenidate (Ritalin)-associated cataract and glaucoma.,Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of Ritalin-associated cataract and glaucoma.,Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: We report a typical symptoms of Charles-Bonnet syndrome (CBS) in patients with severe AMD after intravitreal Avastin-injections.,Charles Bonnet syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"PURPOSE: To describe transient structured visual hallucinations in a patient with vascular age-related macular degeneration (AMD), following an intravitreal Avastin-injection.","Hallucination, visual"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Visual hallucinations after intravitreal injection of bevacizumab in vascular age-related macular degeneration.,"Hallucination, visual"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of metoclopramide-induced oculogyric crisis in a 16-year-old girl with cystic fibrosis.,Oculogyric crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of oculogyric crisis induced by metoclopramide is described in this paper.,Oculogyric crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, cyclosporine dependency is associated with the risk of nephrotoxicity.",Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Quinapril is an angiotensin-converting enzyme inhibitor (ACE-inhibitor) and overdose can lead to prolonged hypotension and, less frequently, transient renal impairment.",Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiomyopathy after widely separated courses of adriamycin exacerbated by actinomycin-D and mithramycin.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Exacerbations of the heart failure were temporally related to the administration of the antitumor antibiotics actinomycin-D (NSC-3053) and mithramycin (NSC-24559).,Cardiac failure congestive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The pathogenic mechanisms involved in the development of adriamycin cardiomyopathy are reviewed, and the possible synergistic effect of other antitumor antibiotics is discussed.",Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiac hypersensitivity and myopericarditis have been reported during long-term treatment with mesalazine.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a man, treated with mesalazine for Crohn's disease who developed drug-induced pericarditis.",Pericarditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute drug induced hepatitis due to erlotinib.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE REPORT: We report a case of acute severe hepatitis resulting from erlotinib monotherapy in a patient with locally advanced pancreatic cancer.,Hepatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Acute severe hepatitis though rare is occasionally observed with EGFR inhibitors gefitinib or erlotinib.,Hepatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity resolved once erlotinib was discontinued and serum transaminases returned to baseline normal values.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Heparin-associated thrombocytopenia and thrombosis is a severe complication of systemic heparin therapy.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This experience supports the hypothesis that heparin can be readministered early to patients with heparin-associated thrombocytopenia and thrombosis, provided antiplatelet therapy is given.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Usefulness of antiplatelet drugs in the management of heparin-associated thrombocytopenia and thrombosis.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: A clinical diagnosis of fixed drug eruption owing to use of the PDE5 inhibitor tadalafil (Cialis) was made.,Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Even though only a few cases of this adverse event have been reported in the literature, severe docetaxel-induced pulmonary toxicity needs to be considered in the differential diagnosis when such patients present with respiratory symptoms.",Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal interstitial pneumonitis associated with docetaxel administration in a patient with hormone-refractory prostate cancer.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The case is presented of a 72-year-old man with hormone-refractory prostate cancer and weekly administration of 30 mg/m2 docetaxel who developed subacute interstitial pneumonitis-related pulmonary fibrosis after seven doses and died despite mechanical ventilation and high-dose corticosteroid treatment.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient presented with fulminant microangiopathic hemolytic anemia and thrombocytopenia within 48 hr of initiating therapy with trimethoprim-sulfamethoxazole.,Microangiopathic haemolytic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombotic thrombocytopenic purpura induced by trimethoprim-sulfamethoxazole in a Jehovah's Witness.,Thrombotic thrombocytopenic purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of Thrombotic Thrombocytopenic Purpura occurring as an allergic response to trimethoprim-sulfamethoxazole therapy (Bactrim, Septra) in a Jehovah's Witness patient.",Thrombotic Thrombocytopenic Purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Juvenile absence epilepsy exacerbated by valproic acid.,Juvenile absence epilepsy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This report describes a case of paradoxical, intravenous valproic acid-induced seizure exacerbation in a child with juvenile absence epilepsy, documented by video-electroencephalography.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute endophthalmitis following intravitreal bevacizumab (Avastin) injection.,Endophthalmitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Infectious endophthalmitis is a potential complication of intravitreal bevacizumab injection.,Endophthalmitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: Two patients with exudative age-related macular degeneration were treated sequentially with an intravitreal injection of bevacizumab and developed signs of severe but painless infectious endophthalmitis 2 days later.,Age-related macular degeneration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report two cases of acute endophthalmitis following intravitreal bevacizumab injection.,Endophthalmitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary hypertension during lithium therapy: clinical case study.,Pulmonary hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors presented a case of pulmonary hypertension during lithium therapy, while she has been on lithium for 6 years.",Pulmonary hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of pulmonary hypertension in an adult patient during lithium therapy.,Pulmonary hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient's arthritis flared after the second infusion of infliximab, which was discontinued.",arthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 32-year-old man with a family history of type 2 diabetes mellitus presented with circulatory collapse and deep coma after 9 days of treatment with perospirone hydrochloride, a recently developed atypical antipsychotic agent available only in Japan.",Circulatory collapse
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The risk of new-onset diabetic ketoacidosis in patients with diabetic risk factors who are taking perospirone hydrochloride or other atypical antipsychotics should be kept in mind.,Diabetic ketoacidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal venous thrombembolism complicating imatinib therapy in a patient with metastatic gastrointestinal stromal tumor.,Embolism venous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The possibility of deep vein thrombosis caused by the compression of the veins by necrotic tumor should be considered in patients with abdominal or pelvic metastases of GIST, including patients treated with imatinib.",Deep vein thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the case of a 50-year-old woman with advanced non-small cell lung cancer who developed status epilepticus shortly after receiving cisplatin and gemcitabine chemotherapy.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Of particular interest in this patient is the fluctuation of the QT interval at a stable dose of methadone, suggesting that a single normal electrocardiogram (ECG) does not guarantee that the patient is not at risk of ventricular arrhythmias.",Electrocardiogram QT interval abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case report of a patient who developed a prolonged QT while being treated with oral methadone for a chronic pain syndrome.,Electrocardiogram QT interval abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"AIMS: To present a case of piloerection after replacing fluvoxamine maleate with milnacipran hydrochloride, and to analyse this effect based on receptor occupancy theory.",Piloerection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The piloerection observed after the replacement of fluvoxamine with milnacipran in this patient appears to have been due to an increase in the alpha(1)-adrenoceptor occupancy by endogenous norepinephrine induced by milnacipran.,Piloerection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Piloerection induced by replacing fluvoxamine with milnacipran.,Piloerection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE PRESENTATION: We report a patient with CF who developed recurrent eosinophilia and severe persistent bronchospasm following repeated administration of preservative-free tobramycin by inhalation, beginning at 16 months of age.",Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Hypersensitivity reaction should be considered in patients who develop recurrent eosinophilia and deterioration of pulmonary function following the use of tobramycin by inhalation or by intravenous administration.,Pulmonary function test decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Inhaled tobramycin solution-associated recurrent eosinophilia and severe persistent bronchospasm in a patient with cystic fibrosis: a case report.,Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The most serious dental side effect of bisphosphonate treatment (particularly when it is administered intravenously) is, paradoxically, osteonecrosis of the mandible or the maxilla represented by exposed nonhealing bone.",Osteonecrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Adverse effects of amiodarone including pulmonary toxicity, hepatotoxicity, aggravation of arrhythmia, and thyroid diseases are well understood.",Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pancreatitis is a very rare adverse effect associated with the use of amiodarone, and only four cases of amiodarone-induced pancreatitis have been reported in literature.",Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Under the suspicion of amiodarone-induced acute pancreatitis, amiodarone was substituted by propafenone.",Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient who developed acute pancreatitis during amiodarone therapy.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: To our knowledge this is the first reported case of tuberculous uveitis following treatment with etanercept.,Uveitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tuberculous uveitis after treatment with etanercept.,Uveitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of tuberculous uveitis due to etanercept.,Uveitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A complex pattern of melanonychia and onycholysis after treatment with pemetrexed for lung cancer.,Nail pigmentation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Infliximab and its serious adverse effects are discussed, and other cases of osteomyelitis with infliximab use are also reviewed.",Osteomyelitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Osteomyelitis occurring during infliximab treatment of severe psoriasis.,Osteomyelitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Based on the Naranjo probability scale, serotonin syndrome was a probable adverse reaction associated with co-administration of citalopram and fentanyl.",Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.",Agitation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Healthcare professionals should be aware of the possible development of serotonin syndrome as a complication of initiation of fentanyl and other phenylpiperidine opioids in patients treated with SSRIs.,Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: To report a case of serotonin syndrome associated with interaction between fentanyl and citalopram, as evidenced by medication history, clinical features and reversal following discontinuation of fentanyl.",Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Serotonin syndrome caused by interaction between citalopram and fentanyl.,Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Renal failure after high-dose methotrexate in a child homozygous for MTHFR C677T polymorphism.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of an 11-year-old female treated for mediastinal T-cell lymphoma who presented renal failure following the second cycle of high-dose methotrexate (HDMTX).,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Docetaxel induced Meibomian duct inflammation and blockage is the likely cause of this presentation in a patient with no history of eyelid masses in the past.,Meibomian gland dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Docetaxel-induced Meibomian duct inflammation and blockage leading to chalazion formation.,Chalazion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 71-year male with castration-resistant metastatic prostate cancer who was treated with weekly docetaxel for 12 weeks and developed significant eye irritation and dryness during treatment.,Eye irritation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of recall pneumonitis induced by gemcitabine is reported.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After having received gemcitabine on day 1 of the second course, the patient developed dry cough, subfebrile temperatures and dyspnea within 48 h.",Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Gemcitabine-induced recall pneumonitis is a rarely reported phenomenon and should be taken into account even after extended time interval to the previous radiotherapy.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Radiation recall pneumonitis induced by gemcitabine.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: For all patients with vancomycin-induced neutropenia, possible cross-reactivity of teicoplanin should be monitored.",Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, a new episode of neutropenia, with a WBC count of 2.8 x 10(3)/mm3 and ANC of 0.448 x 10(3)/mm3, occurred 11 days after teicoplanin initiation.",Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report teicoplanin-related neutropenia that developed after an episode of neutropenia induced by vancomycin therapy.,Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Teicoplanin-induced agranulocytosis that followed vancomycin-induced agranulocytosis suggests a possible cross-reactivity between the 2 drugs.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cutaneous ulceration: an unusual complication of intravenous pentamidine therapy.,Skin ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is a report of a renal transplant patient with Pneumocystis pneumonia who developed chemical cellulitis and ulceration following the extravasation of intravenous pentamidine into the soft tissues of the left hand and forearm.,Cellulitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBSERVATIONS: A 48-year-old woman presented with disfiguring facial edema 10 weeks after she began antiviral therapy with peginterferon alfa-2a and ribavirin for chronic hepatitis C infection.,Face oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tumor-volume increase at beginning of primary treatment with topical interferon alpha 2-beta in a case of conjunctiva-cornea intraepithelial neoplasia.,Tumour marker increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Flecainide overdose can rapidly result in profound cardiovascular collapse, and is associated with a relatively high mortality.",Circulatory collapse
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Managing cardiovascular collapse in severe flecainide overdose without recourse to extracorporeal therapy.,Circulatory collapse
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ezetimibe-induced acute pancreatitis.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since its FDA approval in 2002, there are no known citations of ezetimibe-induced pancreatitis.",Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Selective estrogen receptor modulator raloxifene-associated aggravation of nonalcoholic steatohepatitis.,Non-alcoholic steatohepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first histologically confirmed case of NASH that was aggravated by raloxifene.,Non-alcoholic steatohepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of liver damage following treatment with Danazol for fibrocystic breast disease is reported.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatic damage after danazol treatment.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypersensitivity pneumonitis-like syndrome associated with the use of lenalidomide.,Hypersensitivity pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this report, we describe a patient receiving lenalidomide in whom dyspnea, fever, hypoxia, and diffuse pulmonary infiltrates developed.",Lung infiltration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Physicians should be cognizant of this potential complication in patients receiving thalidomide or thalidomide-like drugs who present with fever and pulmonary infiltrates and fail to improve despite treatment with broad-spectrum antibiotics.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thus, the patient's clinical course and workup strongly support a diagnosis of lenalidomide-induced hypersensitivity pneumonitis-like syndrome.",Hypersensitivity pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intravitreal triamcinolone may have had an influence on the exacerbation of retinochoroiditis in the posterior pole of the patient.,Chorioretinitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 40-year-old man with advanced HIV infection and Mycobacterium avium complex infection experienced rapid cognitive decline after commencement of ethambutol, and symptoms fully resolved with cessation.",Cognitive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ethambutol toxicity manifesting as acute onset psychosis.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Psoriasis induced by interferon-alpha.,Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Recombinant human interferon-alpha has been used in the treatment of several cancers, but there have been several reports that it may exacerbate psoriasis or trigger off its onset.",Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report four patients, three of whom first developed psoriasis and one who had an aggravation of the condition during treatment with interferon-alpha.",Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 61-year-old man with early diffuse cutaneous scleroderma with myositis and progressive interstitial pneumonia developed generalized erythema with high fever 3 weeks after taking sulfamethoxazole/trimethoprim.,Erythema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,INTRODUCTION: We describe the neurointensive care (NIC) management of a patient with severe cerebral swelling and raised intracranial pressure (ICP) after severe sodium valproic acid (VPA) intoxication.,Intracranial pressure increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neurointensive care management of raised intracranial pressure caused by severe valproic acid intoxication.,Intracranial pressure increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bleomycin induced hyperpigmentation with yolk sac tumor.,Pigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The hyperpigmentation was diffuse scattered, flagellate like and linear streaking which was thought to be mainly related to the skin toxicity of bleomycin.",Skin toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a child with yolk sac tumor who developed localized pigmentation after the first course of chemotherapy regimen that included cisplatin, etoposide and bleomycin.",Pigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A cause-effect relationship to capecitabine was suggested due to resolution of headache with capecitabine withdrawal and reappearance with capecitabine rechallenge.,Headache
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,BACKGROUND: Headaches have been reported as a potential side effect of capecitabine therapy.,Headaches
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Capecitabine-induced headache responding to diltiazem.,Headache
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CCBs should be considered in the treatment of 5-FU or capecitabine-induced headaches.,Headaches
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient developed grade 3 capecitabine-induced headache.,Headache
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We hypothesize that capecitabine-induced headache is vascular in nature.,Headache
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Brugada type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome.,Brugada syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of ST elevation in right precordial leads compatible with type 1 Brugada syndrome following administration of propafenone in a patient with Wolff-Parkinson-White syndrome who was receiving lithium at concentrations within therapeutic levels.,Electrocardiogram ST segment elevation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We postulate that gastritis caused by dexamethasone, mucositis caused by doxorubicin, and the unique anatomic nature of a Meckel diverticulum may have contributed to this extremely unlikely and previously unreported event.",Gastritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bortezomib-induced paralytic ileus is a potential gastrointestinal side effect of this first-in-class anticancer proteasome inhibitor.,Gastrointestinal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Paralytic ileus in patients undergoing bortezomib treatment has been reported, although a definite attribution to bortezomib administration has not been established.",Ileus paralytic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a myeloma patient who developed severe paralytic ileus during bortezomib therapy, which presented in the context of progressive constipation without other known causes and which regressed promptly with medical management after drug cessation, suggesting a direct causal relationship.",Ileus paralytic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A woman developed delusional parasitosis when taking phenelzine.,Delusion of parasitosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Delusional parasitosis associated with phenelzine.,Delusion of parasitosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interstitial pneumonitis and alveolar hemorrhage complicating use of rituximab: case report and review of the literature.,Pulmonary alveolar haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The use of rituximab has been uncommonly associated with delayed pulmonary toxicity.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fulminant metoclopramide induced neuroleptic malignant syndrome rapidly responsive to intravenous dantrolene.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of fulminant neuroleptic malignant syndrome in a man aged 70 developing within 12 hours of starting six-hourly intravenous metoclopramide.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The clinical symptoms of gastric mucosa foveolar hyperplasia due to long-term PGE1 therapy simulate hypertrophic pyloric stenosis.,Gastric mucosal hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The results of the ultrasound examination combined with clinical anamnesis allowed diagnosis of gastric mucosa foveolar hyperplasia due to prolonged PGE1 therapy.,Gastric mucosal hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 79-year-old man with ischemic heart disease, chronic atrial fibrillation, chronic renal failure, hypothyroidism, and gout arthritis was hospitalized because of fatigue, myalgia, and leg weakness, shortly after starting treatment with colchicine.",Fatigue
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of colchicine-induced rhabdomyolysis is reported.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Colchicine-induced rhabdomyolysis is a rare complication, and the postulated mechanisms and risk factors for this severe complication are discussed.",Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Colchicine-induced rhabdomyolysis.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Investigation confirmed the diagnosis of rhabdomyolysis, and discontinuation of colchicine resulted in resolution of clinical and biochemical features of rhabdomylysis.",Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,5-Fluorouracil cardiotoxicity complicating treatment of stage IIB cervical cancer--case report.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Acetic acid is corrosive and may cause vagina bleeding.,Vaginal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Induction of systemic lupus erythematosus by interferon-gamma in a patient with rheumatoid arthritis.,systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The development of systemic lupus erythematosus (SLE) after 38 months of therapy with recombinant human interferon gamma (rIFN-gamma) was observed in a patient with rheumatoid arthritis.,Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We assume that rIFN-gamma induced the de novo development of SLE in our patient.,Systemic Systemic lupus erythematosus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bisphosphonate induced osteochemonecrosis of the jaw mimicking a tumour.,Osteonecrosis of jaw
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clozapine-induced eosinophilia and switch to quetiapine in a patient with chronic schizophrenia with suicidal tendencies.,Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug-induced eosinophilia is a non-dose-dependent side effect of clozapine.,Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Occasionally, despite good therapeutic response, clozapine must be stopped due to dangerous side effects such as agranulocytosis.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metformin-associated lactic acidosis (MALA) is a serious metabolic complication that occurs because of metformin accumulation in patients who become dehydrated or developed acute renal failure.,Lactic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metformin-associated lactic acidosis precipitated by diarrhea.,Lactic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An apparent link is described between the use of MMF with prednisone to treat pemphigus vulgaris and the development of red blood cell anemia.,Red blood cell abnormality
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Red blood cell anemia in a patient with pemphigus vulgaris induced by the use of mycophenolate mofetil and prednisone.,Red blood cell abnormality
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The dermatology literature heretofore has not noted that anemia is a side effect of patients taking MMF to treat pemphigus.,Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This report suggests that anemia can occur due to MMF, in particular when it is given with prednisone, a side effect well documented in the transplantation literature when the triple combination of MMF, cyclosporine and prednisone is used.",Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A search of the United States Food and Drug Administration's Adverse Event Reporting System identified nine cases of oxcarbazepine-associated angioedema in pediatric patients aged 16 years and younger.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinical profile of oxcarbazepine-related angioneurotic edema: case report and review.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Oxcarbazepine-associated angioedema manifested by swelling of the face, eyes, lips, or tongue or difficulty swallowing or breathing (or both) is a rare but potentially life-threatening reaction for which early recognition and management are vital.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe in detail the first U.S. case report, of a 4(1/2)-year-old boy who experienced angioedema during treatment with oxcarbazepine.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here we describe another case of VOD occurring after LT, but in which the causative role was played by azathioprine.",Venoocclusive disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One case of tacrolimus-induced hepatic VOD developing after lung transplantation (LT) has been recently reported.,Venoocclusive disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Carbamazepine hypersensitivity syndrome is a rare, life-threatening condition.",Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with chronic myelomonocytic leukemia developed drug-induced pulmonary toxicity after using low dose oral etoposide.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because etoposide-induced pulmonary toxicity is an uncommon but serious adverse event, clinicians must be vigilant about the possibility of it, so that the optimal treatment can start as soon as possible.",Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PET scintigraphy of etoposide-induced pulmonary toxicity.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Detection of antineutrophil cytoplasmic antibody in a patient with L-tryptophan induced eosinophilia-myalgia syndrome.,Eosinophilia-myalgia syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The Center for Disease Control has received numerous reports of an eosinophilia-myalgia syndrome related to products containing L-tryptophan.,Eosinophilia-myalgia syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here, we report a case of RFP-induced hypothyroidism without underlying thyroid disease.",Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rifampin-induced hypothyroidism without underlying thyroid disease.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Rifampin (RFP) increases hepatic microsomal enzyme activity, and there are case reports of RFP-induced hypothyroidism, all associated with Hashimoto's thyroiditis.",Autoimmune thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient is described who developed a rapid onset of pulmonary fibrosis following treatment with a new non-steroidal anti-inflammatory drug, nabumetone.",Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary fibrosis associated with nabumetone.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Cyclosporine is a potent inhibitor of simvastatin metabolism, and may therefore facilitate simvastatin-induced rhabdomyolysis.",Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Discontinuation of simvastatin and cyclosporine resulted in resolution of rhabdomyolysis and normalization of renal function.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Simvastatin-induced rhabdomyolysis following cyclosporine treatment for uveitis.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Generalized lichen nitidus with involvement of the palms following interferon alpha treatment.,Lichen nitidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Here we present the case of a generalized lichen nitidus with involvement of the palms in a patient with hepatitis C after systemic treatment with interferon alpha and ribavirin.,Lichen nitidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is tempting to speculate that interferon alpha may be involved in the pathogenesis of lichen nitidus.,Lichen nitidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sirolimus-eluting stent thrombosis several years after clopidogrel discontinuation.,Vascular stent thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Treatment of APL in pregnancy is controversial as the use of ATRA has been questioned due to the teratogenic effect of retinoids.,Teratogenicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interstitial lung disease (ILD) related to therapy with the drug gefitinib has been well reported.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary toxicity associated with erlotinib.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Similar to reports in patients receiving gefitinib, those with pathologic findings of UIP on resected lung specimens or known pulmonary fibrosis may be at particular risk for erlotinib pulmonary toxicity.",Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case and other published evidence should alert physicians to the possibility of fatal erlotinib-induced ILD.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of fatal pulmonary toxicity in a patient with advanced non-small cell lung cancer who received erlotinib.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It has been reported that fluoroquinolone antimicrobials prolong the corrected QT interval but rarely cause torsade de pointes.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Torsade de pointes associated with moxifloxacin: a rare but potentially fatal adverse event.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,AIM: To report three cases of extensive skin necrosis in cirrhotic patients treated with the vasoconstrictor agent terlipressin (Glypressin).,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Both colchicine and statin therapy may be associated with myopathy, which usually occurs after several months of therapy.",Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rapid onset of muscle weakness (rhabdomyolysis) associated with the combined use of simvastatin and colchicine.,Muscular weakness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The concomitant use, however, of colchicine and statin has been associated with the rapid onset of muscle weakness.",Muscular weakness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of a patient with mild chronic renal insufficiency who had been taking simvastatin for over a year and developed acute weakness within 3 weeks after the start of treatment with colchicine for acute gouty bursitis.,Asthenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pneumocystis carinii pneumonia as a complication of methotrexate treatment of asthma.,Pneumocystis jirovecii pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pneumocystis pneumonia should be considered in asthmatic patients taking methotrexate who present with fever, pulmonary infiltrates, and hypoxia.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE REPORT: A six-year-old boy with transfusion-dependent beta-thalassaemia developed a unilateral hearing loss shortly after commencing desferrioxamine therapy.,Deafness unilateral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Eleven patients developed infection requiring hospitalization while taking leflunomide including: lower respiratory tract infections (3), cellulitis (2), disseminated herpes zoster (2), probable TB liver (1), abdominal sepsis (1), mycotic aneurysm (1) and gastroenteritis (1).",Abdominal sepsis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 58-year-old woman with rheumatoid arthritis (RA) developed fever, skin eruptions, leukocytopenia, and thrombocytopenia, 3 weeks after treatment with sulfasalazine.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sulfasalazine-induced hypersensitivity syndrome and hemophagocytic syndrome associated with reactivation of Epstein-Barr virus.,Haemophagocytic lymphohistiocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case illustrates that the hemophagocytic syndrome associated with reactivation of EBV can occur as part of drug hypersensitivity reactions in RA patients taking sulfasalazine.,Haemophagocytic lymphohistiocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The goal of this study is to describe three patients diagnosed with migraine and epilepsy (both under control) who evolved into status migrainosus after the introduction of oxcarbazepine (OXC), as part of a switch off from carbamazepine (CBZ).",Status migrainosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Uncontrolled headache induced by oxcarbazepine.,Headache
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: A patient with CHF and ESRD developed myoclonic muscle spasms after receiving dobutamine by continuous i.v. infusion.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myoclonus associated with continuous dobutamine infusion in a patient with end-stage renal disease.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: The occurrence of myoclonus associated with continuous i.v. infusion of dobutamine in a patient with end-stage renal disease (ESRD) is described.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reports of colonic perforation as a result of the administration of calcium polystyrene sulfonate and sorbitol are rare.,Large intestine perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We concluded that the colonic ulcer and the sigmoidovesical fistula had been caused by the administration of calcium polystyrene sulfonate and sorbitol.,Large intestinal ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Psychosis in a 12-year-old HIV-positive girl with an increased serum concentration of efavirenz.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report (to our knowledge, for the first time in a child) the emergence of psychosis in a 12-year old white girl with an increased efavirenz concentration and heterozygous gene polymorphism of the CYP2B6-G516T.",Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Mycobacterium marinum infection complicating Crohn's disease, treated with infliximab.",Mycobacterium marinum infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sustained monomorphic ventricular tachycardia after adenosine infusion.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of a sustained monomorphic ventricular tachycardia following adenosine infusion.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Surprisingly, we found that three patients appeared to develop tardive OGC while taking clozapine.",Oculogyric crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tardive oculogyric crisis during treatment with clozapine: report of three cases.,Oculogyric crisis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metronidazole neuropathy.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients are described who developed sensory neuropathy after the ingestion of 30.6 and 114 g metronidazole respectively.,Peripheral sensory neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DIAGNOSIS: Sustained ventricular tachycardia possibly owing to thalidomide treatment.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Multiple syncopal episodes started to occur during thalidomide treatment, and a Holter electrocardiogram showed multiple abnormalities, with an episode of sustained ventricular tachycardia.",Syncope
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sustained ventricular tachycardia in a thalidomide-treated patient with primary plasma-cell leukemia.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient developed typical ECM after subcutaneous selfinjection of glatiramer acetate for multiple sclerosis.,Embolia cutis medicamentosa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Embolia cutis medicamentosa following subcutaneous injection of glatiramer acetate.,Embolia cutis medicamentosa
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case is remarkable since 1) ECM developed after subcutaneous and not after intramuscular injection, 2) the injection was given by the patient himself, and 3) glatiramer acetate can induce skin necrosis as a side effect.",Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although it is difficult to be certain of the direct link of amiodarone on the basis of a single case, it is reasonable to presume that this histopathology is associated with amiodarone-induced hypothyroidism and that involution changes represent the hypofunctional status of this drug-induced disorder.",Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amiodarone is well recognized as an anti-arrhythmic drug containing a high dose of iodine with considerable potential to cause thyroid dysfunction.,Thyroid disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Histopathology of the thyroid in amiodarone-induced hypothyroidism.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report on the histopathological findings of thyroid tissue from a patient with amiodarone-induced hypothyroidism.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although adverse effects are usually mild, the author reports here a case of leucocytopenia and thrombocytopenia with quetiapine treatment that required its discontinuation.",Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Quetiapine-induced leucopenia and thrombocytopenia.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amphotericin B-induced cutaneous leucocytoclastic vasculitis: case report.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Palpable purpuric skin lesions on the anterior surface of both legs appeared on the 55th day of amphotericin B treatment.,Purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of cutaneous leucocytoclastic vasculitis in which amphotericin B might presumably be the aetiological factor.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The incidence of 5-fluorouracil (5-FU)-related cardiotoxicity seems to be dosage and schedule dependent.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient asymptomatic bradycardia in patients on infusional 5-fluorouracil.,Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report such a series of patients who had transient asymptomatic bradycardia after being treated with continuous infusion 5-FU.,Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"According to the Naranjo probability scale, the papular eruption was probably caused by methotrexate.",Rash papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The pathogenesis of methotrexate-induced papular eruption in collagen vascular diseases may suggest cutaneous small-vessel vasculitis.,Rash papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: Methotrexate-induced papular eruption is rarely reported shortly after beginning methotrexate therapy in patients with acute exacerbation of collagen vascular diseases.,Rash papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate-induced papular eruption following treatment of psoriasis has not been previously reported.,Rash papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate-induced papular eruption following treatment of psoriasis.,Rash papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of a diffuse papular eruption following treatment of psoriasis with methotrexate injections.,Rash papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pathogenesis of methotrexate-induced papular eruption in psoriasis may involve immune mechanisms other than those of methotrexate-induced cutaneous vasculitis in collagen vascular disease.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ten hours after the second methotrexate injection, the patient experienced a diffuse pruritic papular eruption located mainly on the limbs.",Rash papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metabolic acidosis induced by acetazolamide.,Metabolic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pericardial hemorrhage due to acetylsalicylic acid in a patient with essential thrombocythemia.,Pericardial haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors describe pericardial hemorrhage, which is related to the use of low-dose acetylsalicylic acid in a patient with essential thrombocythemia.",Pericardial haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"From 1996 to 2002 several medications were changed due to their adverse effects: indinavir (renal colic and fever), nelfinavir (cutaneous rash), and efavirenz (nausea and temporary memory loss).",Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Conventional and diffusion-weighted MRI findings of methotrexate related sub-acute neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case demonstrates the value of DWI in evaluation and diagnosis of sub-acute toxic leukoencephalopathy in patients being treated with methotrexate.,Toxic leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe longitudinal diffusion-weighted MRI findings of sub-acute leukoencephalopathy following methotrexate therapy in a 24-year-old man diagnosed with pre-B-cell acute lymphoblastic leukemia (ALL), presenting with right-sided paralysis and aphasia after second consolidation with intrathecal triple-drug therapy given intrathecally.",Toxic leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,New onset of CD may be considered as an immune-mediated injury induced by etanercept.,Crohn's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,New onset of Crohn's disease during treatment of active ankylosing spondylitis with etanercept.,Crohn's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Typical symptoms of active CD occurred 11, 12, and 26 months after start of etanercept therapy, respectively.",Crohn's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe 3 AS patients treated with etanercept for active AS who developed new onset of CD while AS related symptoms responded well to etanercept.,Crohn's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Upper gastrointestinal haemorrhage is a serious complication of aspirin and clopidogrel (dual) anti-platelet therapy with a high morbidity and mortality.,Upper gastrointestinal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"While doxorubicin was administered, the patient presented thoracic pain and breathing distress due to superior vena cava perforation by the central catheter and subsequent extravasation of the drug into the mediastinum.",Dyspnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe hepatocellular dysfunction following cyproterone acetate therapy.,Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report 3 patients with severe hepatocellular damage due to CPA therapy, 2 with fatal fulminant hepatitis.",Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She was treated with acyclovir and subsequently developed VZV antigen-positive zoster.,Herpes zoster
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"According to the Naranjo adverse drug reaction probability scale, the likelihood that temozolomide was responsible for the adverse drug reaction of fever was probable (score of 6).",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Clinicians should be aware that an erythematous and exfoliative rash may be induced by temozolomide, and be familiar with the pharmacologic and supportive measures necessary for its treatment.",Exfoliative Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Due to the severity of the rash, temozolomide was permanently discontinued.",Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Temozolomide-induced desquamative skin rash in a patient with metastatic melanoma.,Dermatitis exfoliative
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Temozolomide was restarted 2 months later; the patient again developed a fever.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Exfoliative dermatitis secondary to tobramycin sulfate.,Dermatitis exfoliative
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of exfoliative dermatitis clearly linked to intravenous and intraperitoneal administration of tobramycin.,Dermatitis exfoliative
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rituximab-CHOP induced interstitial pneumonitis in patients with disseminated extranodal marginal zone B cell lymphoma.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Phenytoin toxicity: an easily missed cause of cerebellar syndrome.,Cerebellar syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A diagnosis of trastuzumab-induced pneumonitis was made.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A female patient with HER2 positive, metastatic breast cancer presented with pulmonary infiltrates, and a plural effusion dyspnoea after several months of trastuzumab treatment.",Dyspnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Life-threatening interstitial lung disease associated with trastuzumab: case report.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 30-year-old pharmacist suffered from acute allergic contact dermatitis due to 4-chloro-7-nitrobenzofurazan (NBD-Cl).,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Allergic contact dermatitis from 4-chloro-7-nitrobenzofurazan.,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Photo-onycholysis caused by olanzapine and aripiprazole.,Photo-onycholysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a woman who developed photo-onycholysis on multiple nails after uptake of olanzapine.,Photoonycholysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis.,Pulmonary alveolar haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a young man, affected by rheumatoid arthritis who developed a rapid-onset short-of-breath, hemoptysis, and severe weakness, about 2 weeks after the administration of leflunomide.",Haemoptysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hyponatraemia developed after rechallenge with controlled release carbamazepine.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hyponatraemia during low-dose carbamazepine therapy.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the syndrome of inappropriate antidiuresis as a much earlier side-effect of carbamazepine administration in a 29-year Nigerian female patient with generalized tonic-elonic seizures.,antidiuresis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the present paper, we describe two patients with active UC who developed a severe systemic CMV infection during a treatment with an oral microemulsion form of cyclosporine.",Cytomegalovirus infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A short review on imatinib-related hepatotoxicity is also presented.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Imatinib mesylate-related fatal acute hepatic failure in a patient with chronic myeloid leukaemia and chronic hepatitis B infection.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Up to four percent of patients treated with imatinib may develop hepatotoxicity, which usually resolves with discontinuation of the drug.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a 45-year-old Chinese man with CML and chronic hepatitis B virus infection, on imatinib treatment, presenting with herpetic rash and acute liver failure.",Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Clinicians treating elderly patients with olanzapine should be aware of the potential for rapidly developing hyperglycemia and monitor such patients accordingly.,Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of rapidly occurring hyperglycemia that occurred in a geriatric patient 3 days after treatment with olanzapine.,Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rapidly developing hyperglycemia during treatment with olanzapine.,Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Subsequently, he developed hyperglycemia (fasting blood glucose 138 mg/dL) that resolved when olanzapine was stopped and recurred (fasting blood glucose 150 mg/dL) after 2 days of rechallenge with olanzapine 2.5 mg twice daily.",Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"There have been numerous case reports of hyperglycemia with olanzapine in the literature, but none reported hyperglycemia within days of initiation of the medication.",Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin.,Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure.",Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bilateral anterior uveitis associated with clomiphene citrate.,Iridocyclitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report a case of bilateral anterior uveitis associated with ovulation induction therapy using clomiphene citrate.,Iridocyclitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of tics in a thirteen-year-old male following atomoxetine use.,Tic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"There are, however, case studies describing patients experiencing recurrences of tics following treatment with atomoxetine.",Tic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 51-year-old man developed type 1 diabetes mellitus following 24 weeks of treatment with recombinant alpha-2b peginterferon plus ribavirin for chronic hepatitis C.,Type 1 diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The clinical course suggested that recombinant alpha-2b peginterferon plus ribavirin provoked type 1 diabetes mellitus, therefore, in patients who are candidates for interferon therapy the presence of pancreatic autoantibodies and the fasting plasma glucose level should be investigated before and during treatment.",Type 1 diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Type 1 diabetes mellitus provoked by peginterferon alpha-2b plus ribavirin treatment for chronic hepatitis C.,Type 1 diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,BACKGROUND: To describe the occurrence of ocular hypertension in four patients following injection of ranibizumab intravitreally.,Ocular hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Severe and sustained ocular hypertension may occur after intravitreal ranibizumab.,Ocular hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ocular hypertension occurred 1 month after the second ranibizumab injection in patients 1 and 3, and 1 month after the first ranibizumab in patient 2.",Ocular hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Persisent ocular hypertension following intravitreal ranibizumab.,Ocular hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methylphenidate and dextroamphetamine-induced peripheral vasculopathy.,Peripheral vascular disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report 4 patients, 2 on methylphenidate and 2 on dextroamphetamine who presented with acral cyanosis, livedo reticularis, or Raynaud phenomenon.",Cyanosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disseminated eruptive giant mollusca contagiosa in an adult psoriasis patient during efalizumab therapy.,Molluscum contagiosum
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 45-year-old psoriasis patient who developed eruptive mollusca contagiosa during an antipsoriatic treatment with efalizumab.,Molluscum contagiosum
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Gastric tumor, endometrial carcinoma and cervical adenocarcinoma in situ were detected after treatment with tamoxifen for breast cancer.",Cervix carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Incomplete posterior hyaloid detachment after intravitreal pegaptanib injection in diabetic macular edema.,Vitreous detachment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report one case of incomplete posterior hyaloid detachment (PHD) following intravitreal pegaptanib to treat DME.,Vitreous detachment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Enalaprilat induced acute parotitis.,Parotitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present here a female patient who developed acute bilateral parotitis within minutes of i.v. enalaprilat injection and recovered within 24 hours of stopping the drug and with symptomatic treatment.,Parotitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a 4-year-old girl who presented with acute bilateral blindness, a focal seizure and hypertension 10 days after commencing oxybutynin to treat enuresis.",Blindness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe symptomatic hyponatremia during sibutramine therapy: a case report.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The known side effects of sibutramine, ie, hypertension and tachycardia, depend on its adrenergic and serotoninergic effects.",Hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of life-threatening hyponatremia associated with sibutramine use in an obese woman.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Our findings reveal that even in patients without a history of seizures, pregabalin can cause a cortical negative myoclonus.",Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pregabalin-induced cortical negative myoclonus in a patient with neuropathic pain.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a patient who, after receiving his first dose of pregabalin to relieve neuropathic pain, presented with a negative myoclonus.",Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Muzolimine-induced severe neuromyeloencephalopathy: report of seven cases.,Neuromyelitis optica spectrum disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report on 7 patients (2 women, 5 men) with chronic renal failure, who developed under a high dosage of the new diuretic muzolimine (range 240 to 1440 mg per day) fatal neuromyeloencephalopathy.",Neuromyelitis optica spectrum disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,L-asparaginase-induced posterior reversible encephalopathy syndrome during acute lymphoblastic leukemia treatment in children.,Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The purpose of this article is to present the first case-series of posterior reversible encephalopathy syndrome (PRES) associated with L-asparaginase treatment.,Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anastrozole-associated sclerosing glomerulonephritis in a patient with breast cancer.,Glomerulosclerosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Anastrozole may be the causative factor in patients with sclerosing glomerulonephritis.,Glomerulosclerosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Diagnosis of sclerosing glomerulonephritis occurred in this patient during anastrozole use, suggesting a newly defined side effect of anastrozole.",Glomerulosclerosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Renal injury due to anastrozole has not been published in the English literature.,Renal injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"There are major side effects of anastrozole including decrease in both lumbar spine and total hip bone mineral density, increase in the incidence of all bone fractures (especially fractures of spine, hip and wrist), joint disorders and increase in the cholesterol level.",Spinal osteoarthritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We believe that the acute renal failure in our patient was associated with anastrozole.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARY: A 61-year-old woman with no apparent risk factors for liver injury developed acute hepatitis one week after the final dose of a long-term course of pulse itraconazole therapy (200 mg orally twice daily, 1 wk on, 3 wk off, for 24 wk) for onychomycosis.",Hepatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Prolonged exposure to itraconazole, administered either continuously or intermittently, may precipitate severe and irreversible hepatotoxic events.",Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal hepatitis after long-term pulse itraconazole treatment for onychomycosis.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the occurrence of acute cytolytic hepatitis in a patient exposed to pulse itraconazole therapy for 24 weeks and provide a concise review of the literature on cases of itraconazole-induced hepatitis.,Hepatic cytolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Only one case of severe symptomatic hepatitis occurring after pulse therapy with itraconazole for onychomycosis and requiring transplantation has been reported previously.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Intrathecal baclofen can impair sexual function and ejaculation in some patients.,Sexual dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: A male and a female patient with spasticity treated with intrathecal baclofen were recognized to have sexual dysfunction side effects from treatment.,Sexual dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sexual dysfunction associated with intrathecal baclofen use: a report of two cases.,Sexual dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylactic reaction to recombinant insulin-like growth factor-I.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 13 year-old male who developed life-threatening anaphylaxis early in the course of Increlex therapy.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Increasing the olanzapine dosage severely aggravated the symptoms of RLS.,Restless legs syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Restless legs syndrome and periodic limb movements during sleep probably associated with olanzapine.,Periodic limb movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The fifth patient exhibited paraesthesia and agitation caused by olanzapine that was misdiagnosed as psychotic agitation.,Agitation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The fourth patient showed RLS symptoms that were initially caused by a 20-mg daily olanzapine dosage and were later mitigated when olanzapine was reduced and ropinirole was administered.,Restless legs syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The second patient exhibited sudden PLMS following olanzapine injection.,Periodic limb movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The third patient had been suffering from serious akathisia while on risperidone, and was cured after switching to olanzapine, but thereafter the patient suffered from RLS at nighttime.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report five cases of restless legs syndrome (RLS) and periodic limb movements during sleep (PLMS) that were probably associated with olanzapine.,Periodic limb movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Alendronate led to nodular scleritis and rechallenge caused recurrence of scleritis.,Scleritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nodular scleritis following alendronate therapy.,Scleritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To report a case of nodular scleritis following alendronate sodium.,Scleritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two weeks following rechallenge with alendronate sodium resulted in recurrence of his scleritis.,Scleritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition, there is a report on prolonged ECT seizure related to ciprofloxacin, which has an epileptogenic property with a similar action to beta-lactam antibiotics.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thus, tardive seizures in our cases are thought to be related to piperacillin and cefotiam.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute delirium resulting from levofloxacin therapy is an exceedingly rare complication that has been thought to occur more commonly in elderly patients.,Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.",Dizziness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here, we describe levofloxacin-induced delirium with psychotic features in a relatively young, otherwise healthy female.",Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Levofloxacin-induced delirium with psychotic features.,Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: A previously healthy 42-year-old woman presented with acute-onset delirium with psychotic features as a consequence of levofloxacin therapy.,Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Clinicians should be aware that Crohn's disease is a potential novel adverse drug effect of Copaxone.,Crohn's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of Crohn's disease in a patient with multiple sclerosis treated with copaxone.,Crohn's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Our patient developed Crohn's disease while on Copaxone treatment as a consequence of long-term immunosuppression.,Crohn's disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She had been on Copaxone 20 mg/day treatment for 2 years when she first exhibited gastrointestinal symptoms.,Gastrointestinal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors present a case study of a mentally healthy man who repeatedly experienced short-lived, obsessional-like suicidal ideas and images after ingestion of the anti-fungal drug ketoconazole.",Suicidal ideation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"During intravenous treatment with terlipressin for recurrent gastrointestinal (GI) bleeding, a 50-year-old male with no history of heart disease developed a newly prolonged QT interval and torsade de pointes.",Electrocardiogram QT prolonged
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Terlipressin-induced ventricular arrhythmia.,Ventricular arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Spontaneous nasal septal perforation with antiangiogenic bevacizumab therapy.,Nasal septal operation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case describes a 52-year-old white woman who developed a spontaneous nasal septal perforation after given the antiangiogenic drug, bevacizumab, for metastatic ovarian cancer treatment.",Nasal septal operation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 37-year-old woman with relapsing invasive vertebral aspergillosis received intravenous VRC and developed angio-oedema 10 days after starting therapy.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Angio-oedema as an unusual tolerable side effect of voriconazole therapy.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here, we report a case of angio-oedema associated with VRC therapy.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first report of an angio-oedema associated with VRC.",Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Voriconazole (VRC) has not previously been reported to cause angio-oedema.,Angioedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Multiple seizures after bupropion overdose in a small child.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient experienced hallucinations, agitation, vomiting, tachycardia and seizures after ingestion of 1050 (48 mg/kg) of extended-release bupropion.",Agitation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of pediatric bupropion ingestion resulting in multiple seizures.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methylphenidate-associated enuresis in attention deficit hyperactivity disorder.,Enuresis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is a case report of possible association of methylphenidate and enuresis in an 11-year-old boy with attention deficit hyperactivity disorder.,Enuresis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cephalosporin-induced leukopenia following rechallenge with cefoxitin.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Cefazolin was a probable cause of this patient's leukopenia.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe a case of cefazolin-induced leukopenia in a critically ill patient who developed this adverse reaction upon rechallenge with cefoxitin.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Use of the Naranjo probability scale determined the association between cephalosporin use and leukopenia to be probable.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Posterior reversible encephalopathy syndrome (PRES) induced by cyclosporine use in a patient with collapsing focal glomeruloesclerosis.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of PRES in a patient with collapsing focal glomeruloesclerosis (collapsing FGS) with complete recovery after withdrawal of cyclosporine (CSA).,Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Stuttering priapism complicating warfarin therapy in a patient with protein C deficiency.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This therapy was also complicated by Warfarin-induced skin necrosis.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a rare case of recurrent (stuttering) priapism in a patient with protein C deficiency while maintained on Warfarin therapy.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient expired after seven cycles of treatment had been completed because of pulmonary fibrosis and the drug toxicity of bleomycin.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARY: An 80-year-old white female, followed up at the Memory Clinic for mild cognitive impairment, had been taking propafenone 900 mg/d for >10 years for paroxysmal atrial fibrillation without adverse effects.",Cognitive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: This is the first report of a possible interaction between propafenone and citalopram, which caused propafenone adverse effects (eg, dizziness, falls) and mimicked coronary artery disease.",Coronary artery disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three months after starting citalopram, she experienced episodes of chest tightness and dizziness.",Chest discomfort
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Clinicians should be aware of this adverse reaction when facing similar complex neurologic symptoms in patients who are receiving the antibiotic treatment described here, especially vancomycin.",Neurological symptom
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: To our knowledge, this is the first case report illustrating neuralgic amyotrophy triggered by exposure to the antibiotics vancomycin, tobramycin, and piperacillin/tazobactam.",Neuralgic amyotrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Seizures and transient blindness following intravenous pulse methylprednisolone in children with primary glomerulonephritis.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two children, 1 with idiopathic nephrotic syndrome and 1 with endo-extracapillary glomerulonephritis, presented an episode of seizures and transient blindness at different times after i.v. pulse methylprednisolone (IVPMP) treatment.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Based on the Naranjo algorithm, the adverse reaction observed was probably related to the hydroxyurea treatment (score = 6); however, the hydroxyurea chemotherapy could not be discontinued because of the myeloproliferative disorder.",Myeloproliferative neoplasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Both the longitudinal melanonychia and the multiple skin cancers first appeared after approximately 6 months of hydroxyurea treatment.,Nail pigmentation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: We report this case of the concomitant appearance of multiple skin cancers and nail changes associated with hydroxyurea use.,Skin cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hydroxyurea associated with concomitant occurrence of diffuse longitudinal melanonychia and multiple squamous cell carcinomas in an elderly subject.,Nail pigmentation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: The purpose of this study was to report the concomitant occurrence of multiple squamous cell carcinomas and diffuse nail hyperpigmentation associated with hydroxyurea treatment, and to describe a successful therapeutic approach using imiquimod 5%.",Nail pigmentation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient completed a 10-month follow-up, maintaining a complete resolution of the treated skin lesions; however, the development of a painful hand ulcer, possibly associated with the hydroxyurea, and new skin cancers were observed at the last follow-up visit.",Ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Vanishing bile duct and Stevens-Johnson syndrome associated with ciprofloxacin treated with tacrolimus.,Stevens-Johnson syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of a patient with ciprofloxacin-induced SJS and acute onset of VBDS, and reviewed the related literature.",Stevens-Johnson syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 64 year old woman with previous history of coronary stenting five days before was admitted in our institution for intracranial bleeding while receiving aspirin and clopidogrel.,Haemorrhage intracranial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disseminated salmonellosis in a patient treated with temozolomide.,Salmonellosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the first case of disseminated salmonellosis in a patient treated with temozolomide.,Salmonellosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ceftriaxone-induced fixed drug eruption: first report.,Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"FDE from cephalosporins has been rarely reported, and to the best of our knowledge there is no published report of ceftriaxone-induced FDE in the literature.",Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of a 54-year-old Turkish woman who presented with ceftriaxone-induced FDE.,Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: All doctors need to be aware of the need to review the indications for gabapentin use during periods of acute illness, especially with regard to renal impairment.",Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gabapentin toxicity in renal failure: the importance of dose adjustment.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: This case report outlines a significant type of morbidity due to continued use of gabapentin during an episode of acute renal failure.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute syphilitic posterior placoid chorioretinitis following intravitreal triamcinolone acetonide injection.,Chorioretinitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,BACKGROUND: We describe the ophthalmic features and clinical course of two cases of acute syphilitic posterior placoid chorioretinitis (ASPPC) that developed after intravitreal triamcinolone acetonide (IVTA) injection.,Chorioretinitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The fundus picture shown in these cases may be typical of ASPPC after IVTA injection.,Chorioretinitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Two patients with ocular inflammation of unknown origin developed severe chorioretinitis after IVTA injection.,Chorioretinitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although it is difficult to solely attribute intratumoral hemorrhage to aspirin, we have to be careful when prescribing aspirin for patients who have asymptomatic meningioma.",Tumour haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hemorrhage from a falx meningioma after internal use of low-dose aspirin.,Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On the other hand, aspirin may have promoted the enlargement of spontaneous hemorrhage from meningioma.",enlargement of spontaneous Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Our case is the second one in which hemorrhage from a meningioma may have been induced by aspirin prophylaxis.,Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case in which hemorrhage occurred in an asymptomatic falx meningioma known beforehand, after the internal use of low-dose aspirin for 16 months.",Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute coronary syndromes can be associated with the infusion of rituximab.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute coronary syndromes complicating the first infusion of rituximab.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The aim of this study was to describe the occurrence of acute coronary syndromes in 3 cases of rituximab infusions.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The occurrence of symptoms that could be ascribed to an acute coronary syndrome should always be taken seriously during the first rituximab infusion and investigated aggressively.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We reviewed the records of 3 patients with lymphoproliferative disorders who experienced acute coronary syndromes associated with their initial infusion of rituximab.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: This report describes a case of a probable interaction between topical econazole lotion 1% and acenocoumarol that resulted in overanticoagulation and a life-threatening laryngeal hematoma in this elderly patient.,Laryngeal haematoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Laryngeal dyspnea in relation to an interaction between acenocoumarol and topical econazole lotion.,Laryngeal dyspnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Adrenal suppression in a fetus due to administration of methylprednisolone has hitherto been rarely published.,Adrenal insufficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Life-threatening adrenal suppression, requiring hydrocortisone supplementation and intensive therapy, was observed and successfully treated in a newborn, whose mother had received high-dose methylprednisolone in late pregnancy.",Adrenal insufficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,High-dose methylprednisolone in a pregnant woman with Crohn's disease and adrenal suppression in her newborn.,Adrenal insufficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 10-year-old asthmatic boy began to suffer from urticarial rash and moderately severe bronchospasm after 8 weeks' treatment with disodium cromoglycate.,Bronchospasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Asthma and urticaria during disodium cromoglycate treatment.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When DSCG was withdrawn, urticaria vanished and the child remained symptom-free.",Urticaria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After the first oral dose of propranolol, syncope developed together with atrioventricular block.",Atrioventricular block
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Syncope induced by propranolol in hypertrophic cardiomyopathy.,Syncope
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Olanzapine-induced hyperglycaemic coma and neuroleptic malignant syndrome: case report and review of literature.,Diabetic hyperglycaemic coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: The main adverse effects of leflunomide consist of diarrhea, nausea, liver enzyme elevation, hypertension, alopecia, and allergic skin reactions.",Dermatitis allergic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Leflunomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this report we described a case of juvenile idiopathic arthritis patient who developed thymic enlargement (true thymic hyperplasia), mediastinal lymphadenopathy and pleurisy associated with systemic symptoms under Etanercept treatment.",Lymphadenopathy mediastinal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thymic enlargement in a patient with juvenile idiopathic arthritis during etanercept therapy.,Hyperplasia of thymic epithelium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Oxcarbazepine-induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).,Drug reaction with eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is an image and brief case report of a 13-year-old boy who presented with severe rash and systemic symptoms after starting oxcarbazepine.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,After treatment with a beta-sympathomimetic drug (Partusisten) one fetus developed supraventricular tachycardia.,Supraventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rosaceiform eruption induced by erlotinib.,Rosacea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The aim of this paper is to report the case of rosaceiform eruption induced by erlotinib in an 81-year-old-man and to discuss the pathogenetic role of Demodex folliculorum mites, found in the present patient, using skin scraping.",Rosacea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In patients with methotrexate-induced anaphylaxis, discontinuation of treatment may increase the risk of death due to cancer progression.",Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Management and successful desensitization in methotrexate-induced anaphylaxis.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thus, we confirm that desensitization may be a safe procedure in patients with cancer who experience methotrexate-induced anaphylaxis.",Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a child with metastatic osteosarcoma, who experienced an anaphylactic/anaphylactoid reaction to methotrexate.",Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug-induced fever due to diltiazem.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug-induced fever should be considered in patients who have unexplained high temperatures during diltiazem therapy.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, drug-induced fever has not been reported with the use of diltiazem hydrochloride, a commonly prescribed calcium channel blocker.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of congestive heart failure in a child with Wilms' tumor treated Adriamycin is presented and discussed.,Cardiac failure congestive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Radiologic recognition of adriamycin cardiotoxicity.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The role of Adriamycin in the production of cardiotoxicity is reviewed.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carbamazepine-induced Diabetes mellitus.,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diabetes Mellitus was observed in a patient given carbamazepine.,Diabetes Mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although heparin-dependent antibodies (HDAs) typically manifest with thrombocytopenia as in heparin-induced thrombocytopenia (HIT), they may also manifest with preserved platelet counts.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinicians should be cognizant of this possibility and consider a diagnosis of HDAs in patients with ongoing thrombosis who are receiving heparin therapy.,Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Heparin-dependent antibodies and thrombosis without heparin-induced thrombocytopenia.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Despite these antithrombotic effects, the patient developed repeated venous thromboembolism during treatment with low-molecular-weight heparin.",Embolism venous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Four months after receiving an orthotopic liver transplant, a 51-year-old man was admitted for progressive liver failure and severe hepatocellular necrosis thought to be due to tacrolimus.",Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Initiation of posaconazole led to clinical improvement until the patient's demise from bacteremic vancomycin-resistant enterococcal peritonitis.,Peritonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Iatrogenic Cushing syndrome after epidural triamcinolone injections in an HIV type 1-infected patient receiving therapy with ritonavir-lopinavir.,Cushing's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the first case of a human immunodeficiency virus type 1 (HIV-1)-infected individual receiving combination antiretroviral therapy, which included ritonavir, who developed Cushing syndrome with profound complications after epidural triamcinolone injections.",Cushing's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 22-year-old drug-abuser injected flunitrazepam tablets dissolved in tap water into her left femoral artery and presented with clinical signs of acute ischaemia of the left leg.,Peripheral ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute ischaemia of the leg following accidental intra-arterial injection of dissolved flunitrazepam tablets.,Peripheral ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 17-year-old boy with refractory psoriatic arthritis and alpha-1 antitrypsin deficiency who developed a syringotropic hypersensitivity reaction after 9 months of therapy with infliximab and leflunomide is described.,Sweat gland tumour
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Syringotropic hypersensitivity reaction associated with infliximab and leflunomide combination therapy in a child with psoriatic arthritis.,Sweat gland tumour
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of severe aplastic anemia secondary to treatment with lenalidomide for multiple myeloma.,Aplastic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although moderate myelosuppression is not uncommonly seen in patients treated with lenalidomide, aplastic anemia has not previously been reported to be associated with this agent.",Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of severe aplastic anemia (AA) that was probably induced by lenalidomide.,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After cessation of amantadine, the edema resolved, and the endothelial cell densities were <or=600/mm.",Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Amantadine can cause reversible corneal edema but can irreversibly reduce the density of endothelial cells.,Corneal oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Corneal edema recurred when the administration of amantadine was resumed.,Corneal oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Corneal endothelial dysfunction associated with amantadine toxicity.,Corneal dystrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To describe bilateral corneal endothelial dysfunction in a patient with Parkinson disease who was treated with long-term amantadine.,Corneal dystrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: A 52-year-old woman with Parkinson disease who had taken amantadine for 6 years had bilateral corneal edema for 2 months at baseline.,Corneal oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Biopsy-proven acute interstitial nephritis associated with the tyrosine kinase inhibitor sunitinib: a class effect?,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first biopsy confirmed occurrence of acute interstitial nephritis in a patient receiving treatment with Sunitinib for metastatic renal cell cancer.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Extrapyramidal symptoms are well-documented complications of therapy with haloperidol, even when small doses are used.",Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report highlights a case of drug-induced dysphagia in a patient receiving haloperidol for obsessive nocturnal thoughts and auditory disturbances.,Dysphagia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 52 year-old male patient diagnosed of ankylosing spondylitis presented with an iron deficiency anemia after a ten-month treatment of methotrexate.,Iron deficiency anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate induced sprue-like syndrome.,Malabsorption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Only 3 cases of imatinib-induced tumor lysis syndrome have been reported.,Tumour lysis syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We herein described an additional patient with BCR-ABL (ela2) positive acute lymphoblastic leukemia who developed tumor lysis syndrome after 10-day treatment with imatinib.,Tumour lysis syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,IFNalpha-induced recurrence of Graves' disease ten years after thyroidectomy in chronic viral hepatitis C.,Graves' disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In contrast to chronic or subacute thyroiditis, Graves' disease rarely complicates IFN-alpha therapy for chronic viral C hepatitis.",Graves' disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a 51-year-old man in whom IFN-alpha treatment was followed by recurrence of Graves' disease 10 years after thyroidectomy was performed and the patient was declared cured.,Graves' disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interstitial granulomatous dermatitis associated with darifenacin.,Interstitial granulomatous dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors describe a case of interstitial granulomatous dermatitis associated with darifenacin.,Interstitial granulomatous dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Gemcitabine is a known risk factor for hemolytic uremic syndrome (HUS), which can often have a rapidly fatal clinical course despite intervention with steroids, plasmapheresis and hemodialysis.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"METHODS: A retrospective report of the first case of gemcitabine-related HUS, in a patient with metastatic pancreatic adenocarcinoma, treated with a variety of standard therapies in addition to rituximab is presented.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rituximab-based therapy for gemcitabine-induced hemolytic uremic syndrome in a patient with metastatic pancreatic adenocarcinoma: a case report.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia.,Drug reaction with eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of chlorambucil-induced DRESS syndrome in a 70-year-old man recently diagnosed with chronic lymphocytic leukaemia.,Drug reaction with eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 10-year-old boy with osteosarcoma and normal renal function manifested laboratory evidence of impending renal toxicity and extreme elevation of aspartate aminotrasferase and alanine aminotransferase within 2 hours after the completion of a 4-hour infusion of high-dose methotrexate (MTX) (12 g/m2), and went on to develop acute renal failure with life-threatening hyperkalemia 29 hours later.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although his renal function recovered completely with high-dose leucovorin, hemodialysis, charcoal hemoperfusion, and carboxypeptidase G2, we present this case to emphasize that signs of renal toxicity may be present as early as 2 hours after the completion of a 4-hour MTX infusion, and to suggest that monitoring for MTX toxicity should perhaps begin within a few hours after the completion of 4-hour MTX infusion.",Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Early recognition of renal toxicity of high-dose methotrexate therapy: a case report.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Multifocal electroretinographic abnormalities in ethambutol-induced visual loss.,Loss of visual contrast sensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These are the first reported patients to show mfERG abnormalities that correspond to bitemporal visual field defects and add to the growing evidence that ethambutol damages the retina.,Hemianopia heteronymous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients who developed decreased visual acuity after several months of ethambutol treatment for Mycobacterium avium-intracellulare infection had bitemporal visual field defects that suggested optic chiasm damage.,Hemianopia heteronymous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tenofovir-associated nephrotoxicity in two HIV-infected adolescent males.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, these cases represent the first reports of TDF-associated irreversible renal failure and rickets in pediatric patients.",Chronic kidney disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two cases of tenofovir (TDF)-associated nephrotoxicity in perinatally HIV-infected adolescents.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this case, discontinuing piroxicam, a nonsteroidal anti-inflammatory drug, and starting a palliative treatment plan helped resolve a patient's ulcers.",Ulcers
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure following intravenous immunoglobulin therapy in a HIV-infected patient.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure is a rare complication following the administration of intravenous immunoglobulin (IVIG).,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The exact mechanism of IVIG-associated acute renal failure remains unclear.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 58-year-old man with advanced renal cell carcinoma developed grade 3 proteinuria (8.5 g/24 h) without microscopic hematuria or renal insufficiency five days after temsirolimus infusion.,Proteinuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Temsirolimus-induced glomerulopathy.,Glomerulonephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Hypoglycemia can be a serious side effect of etanercept in patients already on antidiabetic medications known to cause hypoglycemia, such as sulfonylureas, meglitinides, and insulin.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Persistent hypoglycemia in a patient with diabetes taking etanercept for the treatment of psoriasis.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a patient with type 2 diabetes mellitus who, while treated with the antitumor necrosis factor-alpha blocking agent etanercept for severe plaque psoriasis, experienced persistent hypoglycemia requiring the lowering and eventual elimination of his previous insulin regimen.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on three cases wherein treatment of dexmedetomidine-induced bradycardia with i.v. glycopyrrolate (5.0 microg/kg) not only resulting in resolution of bradycardia but also resulting in an exaggerated increase of arterial blood pressure.,Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is reported in up to 18.6% of patients treated with intravenous bisphosphonates and can result in significant morbidity.,Osteonecrosis of the jaw
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bisphosphonate-related osteonecrosis of the skull base.,Osteonecrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A previous study of patients with ""quinine-associated TTP/HUS"" found that ADAMTS13 activities were not abnormal in 12/12 patients.",Thrombotic thrombocytopenic purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A retrospective review of TTP patients with quinine-associated thrombotic microangiopathy (TMA) for whom ADAMTS13 was measured before plasma exchange was performed.,Thrombotic microangiopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thrombocytopenia with or without microangiopathy following quinine is often referred to as quinine ""hypersensitivity."" When schistocytes are present it is frequently termed ""quinine-associated TTP/HUS."" A severe deficiency of the vWF-cleaving protease, ADAMTS13, is associated with idiopathic TTP.",Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We conclude that while thrombocytopenia and schistocytosis can be seen in quinine-associated TTP/HUS, the pathophysiology seems to be distinct from that seen in most cases of idiopathic TTP (i.e., severely decreased ADAMTS13 with an inhibitor).",Schistocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We recommend that a TMA in association with quinine be consistently referred to as quinine-associated thrombotic microangiopathy (quinine-TMA) to better distinguish this entity from idiopathic TTP.,Thrombotic microangiopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Complications associated with primary and secondary perforation of the bladder following immediate instillations of epirubicin after transurethral resection of superficial urothelial tumours.,Bladder perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,MATERIALS AND METHODS: We present two cases of significant morbidity related to primary and secondary perforation of the bladder following two instillations of epirubicin.,Bladder perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Aliskiren-associated acute renal failure with hyperkalemia.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of acute renal failure with hyperkalemia associated with the recently marketed direct renin inhibitor aliskiren.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of acute cardiomyopathy and pericarditis associated with methylphenidate.,Cardiomyopathy acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, acute cardiomyopathy and pericarditis secondary to methylphenidate use has been rarely reported.",Cardiomyopathy acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a 17-year-old male who developed chest pain, elevated cardiac biomarkers, and acute left ventricular dysfunction following a single dose of methylphenidate.",Left ventricular dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"According to the Naranjo et al. adverse-reaction probability scale, enoxaparin was the probable cause of hepatotoxicity in this patient.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: A woman receiving enoxaparin every 12 hours developed signs and symptoms of hepatotoxicity after the second dose.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Probable enoxaparin-induced hepatotoxicity.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: A case of probable enoxaparin-induced hepatotoxicity is described.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Posterior reversible encephalopathy syndrome associated with methotrexate neurotoxicity: conventional magnetic resonance and diffusion-weighted imaging findings.,Posterior reversible encephalopathy syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The addition of intrathecal methotrexate to treatment protocols has increased survival rates in children with acute lymphoblastic leukemia but is also associated with varying degrees of neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a 15-year-old female patient diagnosed with acute lymphoblastic leukemia presenting with status epilepticus after receiving intrathecal methotrexate.,Acute lymphocytic leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cyclosporine-induced pain syndrome in a child undergoing hematopoietic stem cell transplant.,Pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this case, CIPS was considered to be probably associated with cyclosporine according to the Naranjo probability scale.",Chronic inflammatory demyelinating polyradiculoneuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of calcineurin-induced pain syndrome (CIPS) in a child undergoing his second hematopoietic stem cell transplant (HSCT).,Pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"With the first cyclosporine dose, the patient complained of leg pain that was most severe during the cyclosporine infusion.",Pain in extremity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neuroleptic malignant syndrome due to risperidone treatment in a child with Joubert syndrome.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report describes a case of neuroleptic malignant syndrome due to risperidone in a child with Joubert syndrome.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of tuberculosis in a patient on Efalizumab and Etanercept for treatment of refractory palmopustular psoriasis and psoriatic arthritis.,Tuberculosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The most common complication of warfarin use is adverse bleeding.,Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE REPORT: We describe here a case of a 60 year old female that experienced a relapse of symptomatic hyperlactatemia after being switched from stavudine to zidovudine and how the case was managed at the Infectious Diseases Institute, Kampala, Uganda.",Hyperlactacidaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: This case shows that switching to zidovudine potentially can lead to a hyperlactatemia relapse.,Lactic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,INTRODUCTION: In resource limited settings patients on antiretroviral treatment who develop stavudine induced hyperlactatemia are often switched to zidovudine on the basis of published studies that demonstrate that this agent can be a safe alternative.,Hyperlactacidaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylactic reaction to bacitracin ointment.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of an 11-year-old boy who experienced an anaphylactic reaction after administration of bacitracin ointment.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Herein, we present a patient with severe and prolonged hypoglycemia after long-acting octreotide treatment.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypoglycemia induced by long-acting somatostatin analogues in a patient with nonfunctional neuroendocrine tumor.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In these patients, long-acting octreotide may trigger serious hypoglycemia.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Leukopenia due to parvovirus B19 in a Crohn's disease patient using azathioprine.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The uncomplicated long-term use of adequately-dosed AZA and stable non-toxic metabolite levels could not acknowledge TPMT deficiency as a primary cause of the leukopenia.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present the case of an adult Crohn's disease patient with a parvovirus B19 infection and leukopenia during long-term AZA therapy.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Isoniazid causing breast tissue enlargement has been very rarely reported.,Breast enlargement
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Isoniazid induced gynaecomastia: a case report.,Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cryptococcus neoformans fatal sepsis in a chronic lymphocytic leukemia patient treated with alemtuzumab: case report and review of the literature.,Sepsis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The international literature regarding opportunistic infections after immunosuppressive therapy with alemtuzumab with particular attention on fungal infections has also been reviewed.,Fungal infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Secondary acute myeloid leukemia after etoposide therapy for haemophagocytic lymphohistiocytosis.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The risk of developing sAML is estimated to be between 1% and 5%, 2-20 years after exposure to etoposide but may also be related to cumulative drug doses, treatment schedules, host factors and co-administration of other antineoplastic agents.",Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients with HLH developed etoposide-related secondary acute myeloid leukemia (sAML) following therapy for HLH.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Polymyoclonus seizure resulting from accidental injection of tranexamic acid in spinal anesthesia.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rhabdomyolysis following clarithromycin monotherapy.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of rhabdomyolysis related to the administration of clarithromycin without concurrent use of other medications.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, re-initiation of sunitinib treatment was followed by bilateral breast enlargement again.",Breast enlargement
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Onset of male gynaecomastia in a patient treated with sunitinib for metastatic renal cell carcinoma.,Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The mechanism by which sunitinib induces gynaecomastia is thought to be associated with an unknown direct action on breast hormonal receptors.,Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The more common grade 3 or 4 adverse effects of sunitinib include hypertension, fatigue, hand-foot syndrome, elevated lipase and lymphopenia.",Lipase increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Divalproex sodium-induced eosinophilic pleural effusion.,Eosinophilic pleural Effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of 48-year-old woman with seizure disorder on divalproex sodium (Depakote) who presented with dyspnea.,Dyspnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Withdrawal of Depakote resulted in resolution of the effusion.,Effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Flurbiprofen-associated acute tubulointerstitial nephritis.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of biopsy-proven acute tubulointerstitial nephritis associated with a second course of flurbiprofen, a nonsteroidal anti-inflammatory drug of the propionic acid class.",Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Stupor and fast activity on electroencephalography in a child treated with valproate.,Stupor
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The case of a 4-year-old girl with valproate-induced stupor and electroencephalographic pattern of increased fast activity is reported.,Stupor
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This article presents a case of an atypical localized cutaneous eruption with an unusual course and protracted resolution time associated with sorafenib therapy.,Dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"According to the Naranjo adverse drug reaction probability scale, tigecycline was the probable cause of her acute pancreatitis.",Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Following 7 days of tigecycline she developed severe abdominal pain and elevated pancreatic enzymes suggesting acute pancreatitis.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pancreatitis has been associated with the tetracycline class of antibiotics and concerns about tigecycline-induced acute pancreatitis have recently been raised.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tigecycline-induced acute pancreatitis: case report and literature review.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We recommend that clinicians monitor patients for signs and symptoms of pancreatitis, including abdominal pain, during treatment with tigecycline.",Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug induced polymyositis secondary to leuprolide acetate (Lupron) therapy for prostate carcinoma.,Polymyositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of biopsy proven myositis whose symptoms began within 10 days of receiving leuprolide acetate therapy for prostate cancer.,Myositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Aripiprazole-induced hiccups: a case report.,Hiccups
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient of organic bipolar affective disorder who developed hiccups with the atypical antipsychotic aripiprazole.,Hiccups
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: This patient's rhabdomyolysis was probably induced by sertraline therapy.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: The Naranjo probability scale indicated a probable relationship between sertraline treatment and the onset of rhabdomyolysis.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe a case of sertraline-induced rhabdomyolysis in an elderly patient with dementia and comorbidities.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sertraline-induced rhabdomyolysis in an elderly patient with dementia and comorbidities.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient's other comorbidities and medications have not been suggested as possible interactions with sertraline that can cause rhabdomyolysis.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tumor lysis syndrome after transcatheter arterial infusion of cisplatin and embolization therapy for liver metastases of melanoma.,Tumour lysis syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,He had priapism following the use of olanzapine.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Priapism associated with olanzapine.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Can ketamine prescribed for pain cause damage to the urinary tract?,Urinary tract injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Presentation of three palliative care patients who were given ketamine as an analgesic and subsequently developed significant and debilitating urological symptoms.,Lower urinary tract symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These two cases highlight the importance of considering lopinavir/ritonavir induced arrhythmias when dealing with HIV-positive individuals.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Colitis as a manifestation of infliximab-associated disseminated cryptococcosis.,Colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After three weeks of carbamazepine therapy, the patient arrived at the emergency department (ED) with severe agitation and aggressive behavior.",Aggression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carbamazepine-induced hyperammonemia.,Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: A 26-year-old man with bipolar disorder developed hyperammonemia three weeks after initiating carbamazepine therapy.,Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,He had also developed elevated serum ammonia levels while on valproic acid.,Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: A case of carbamazepine-induced hyperammonemia is presented.,Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Adriamycin-induced cardiomyopathy aggravated by cis-platinum nephrotoxicity requiring dialysis.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Complications of chemotherapy for a synovial sarcoma in an eight-year old boy included cisplatinum nephrotoxicity and adriamycin cardiotoxicity.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 65-year-old female patient presented with jaundice followed 2 days later by severe dyspnea and tachypnea which worsened when patient was lying flat, 1 week after the fourth dose of adalimumab.",Jaundice
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of acute respiratory failure due to diaphragmatic weakness following adalimumab therapy for psoriasis is described.,Acute Respiratory failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute bilateral phrenic neuropathy following treatment with adalimumab.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The potential development of SJS/TEN, a severe life-threatening illness, emphasizes the need for judicious use of TMP-Sx and close monitoring and follow-up for patients who were given TMP-Sx for SSTIs.",SJS-TEN overlap
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) secondary to trimethoprim-sulfamethoxazole (TMP-Sx) therapy for presumed community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection.,SJS-TEN overlap
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Spontaneous hemothorax is a rare phenomenon in conjunction with LMWH but should be considered in cases of acute respiratory distress following commencement of LMWH.,Haemothorax
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On day 4, following 3 doses of dalteparin, the patient developed acute respiratory distress attributable to a massive right hemothorax confirmed by computed tomography pulmonary angiography (CTPA) and intercostal drainage of 1500 mL of frank blood.",Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Spontaneous hemothorax following anticoagulation with low-molecular-weight heparin.,Haemothorax
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute vision loss after intravitreal injection of bevacizumab (avastin) associated with ocular ischemic syndrome.,Blindness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,AIM: To report a patient with diabetic rubeosis who suffered from acute retinal ischemic change and stroke after intravitreal injection of bevacizumab.,Retinal vein occlusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Patients receiving intravitreal injections of bevacizumab should be evaluated for potential systemic risk factors such as carotid insufficiency, coagulopathy and poorly controlled diabetes mellitus.",Carotid artery insufficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three days after intravitreal injection of bevacizumab, acute ocular ischemic syndrome occurred.",Retinal vein occlusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three days after receiving intravitreal injection of bevacizumab (1.25 mg in 0.1 ml), he developed acute vision loss and change of consciousness.",Blindness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Herein, we describe a patient with AIDS who presented to medical attention with pancytopenia 48 months postchemotherapy with etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (R-EPOCH) for diffuse large B-cell lymphoma.",Pancytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Favorable outcome of de novo hepatitis B infection after liver transplantation with lamivudine and adefovir therapy.,Hepatic infection bacterial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Linezolid-associated acute interstitial nephritis and drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On day 7 of linezolid treatment, the patient developed severe pruritus, macular rash, facial edema, eosinophilia, marked increase in serum creatinine level, and mild hepatitis.",Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case of linezolid-associated acute interstitial nephritis within the context of a drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a patient treated with linezolid raises concerns about the presumed renal safety of this drug.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Increased awareness is needed on the possible occurrence of LPD resembling gastric cancer in rheumatoid arthritis patients treated with MTX.,Lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible methotrexate-associated lymphoproliferative disorder resembling advanced gastric cancer in a patient with rheumatoid arthritis.,Lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She was diagnosed with Epstein-Barr virus-associated polymorphic lymphoproliferative disorder (LPD) due to immunodeficiency caused by MTX administration.,Lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first case of spontaneous remission of MTX-associated gastric LPD after discontinuation of MTX therapy.",Lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, he developed acute renal failure, hyperkalemia, and hyperuricemia 30 d after receiving the sorafenib treatment.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sorafenib induced tumor lysis syndrome in an advanced hepatocellular carcinoma patient.,Tumour lysis syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Are nasal decongestants safer than rhinitis? A case of oxymetazoline-induced syncope.,Syncope
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report here a case of cardiovascular and neurological depression induced by oxymetalzoline in a toddler.,Depression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Given that discontinuation of nitrofurantoin and introduction of methylprednisolon therapy significantly lowered liver enzyme levels, restoring most of them to normal, we concluded that this was probably the case of toxic liver damage caused by nitrofurantoin.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nitrofurantoin-induced acute liver damage in pregnancy.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 40-year-old man with relapsing-remitting multiple sclerosis (MS) developed primary central nervous system lymphoma (PCNSL) after having received 21 doses of natalizumab monotherapy.,Central nervous system lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Primary central nervous system lymphoma in a patient treated with natalizumab.,Central nervous system lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The first patient is undergoing hemodialysis and, though responding to sunitinib, is having significant fatigue and hypertension.",Fatigue
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of severe apnea in an infant exposed to lamotrigine through breast-feeding.,Apnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe apnea in an infant exposed to lamotrigine in breast milk.,Apnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The Naranjo probability scale indicated a probable relationship between apnea and exposure to lamotrigine through breast-feeding in this infant.,Apnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although there have been numerous reports of effusions, none have provided complete pleural fluid analysis; therefore, we report 2 patients with dasatinib-induced pleural effusion with complete pleural fluid analysis.",Pleural effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dasatinib-induced pleural effusions: a lymphatic network disorder?,Pleural effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: One case of recurrent primary peritoneal carcinoma previously treated with a carboplatin-based regimen, developed a platinum hypersensitivity.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"One week after the initial-dose of adalimumab (160 mg), which was initiated due to an acute exacerbation of Crohn's disease, the patient developed a fulminant cardiomyopathy.",Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe cardiomyopathy following treatment with the tumour necrosis factor-alpha inhibitor adalimumab for Crohn's disease.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amikacin-induced type 5 Bartter-like syndrome with severe hypocalcemia.,Hypocalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Recovery of the tubular dysfunction took 15 days following cessation of the offending drug, Amikacin.",Renal tubular dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We discuss a patient who developed severe renal tubular dysfunction secondary to short-term therapy with Amikacin, resulting in refractory hypokalemia, hypocalcemia, hypomagnesemia, metabolic alkalosis, and polyuria.",Hypocalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Postoperatively, the first two patients treated with 1 to 2 cc of thrombin were slow to awaken; one had evidence of vasospasm by transcranial Doppler ultrasound studies and multiple infarcts on cranial computerized tomography, while the other had a moderate-sized frontal hematoma with intracranial hypertension.",Cerebral infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thrombin is highly effective for stopping intractable arterial hemorrhage during stereotactic brain biopsy; however, it is a vasospastic agent and may have been responsible for the cerebral infarctions in one patient.",Cerebral infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ciprofloxacin-induced hemorrhagic vasculitis.,Haemorrhagic vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ciprofloxacin-induced hemorrhagic vasculitis is a rare side effect.,Haemorrhagic vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ciprofloxacin is among the standard treatments for infected ischemic ulcers; in the rare case of ciprofloxacin-induced hemorrhagic vasculitis, it might be interpreted as progression of infection, instead of a complication of the treatment, thus leading to faulty diagnosis and treatment.",Haemorrhagic vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In one patient the vasculitis resolved after termination of the ciprofloxacin therapy; in the other patient the ciprofloxacin-induced hemorrhagic vasculitis was superimposed on a severe forefoot infection, leading to progressive gangrene and a below-knee amputation.",Leg amputation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, a recent post-marketing survey in Japan revealed that interstitial pneumonia occurred in 4 among approximately 2 000 Japanese patients treated with sorafenib.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interstitial pneumonia probably associated with sorafenib treatment: An alert of an adverse event.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this article, we describe a Japanese patient with severe interstitial pneumonia probably caused by sorafenib treatment for metastatic renal cell carcinoma.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Oncologists supervising future clinical trials for lung cancer should be alert to the fact that sorafenib can potentially induce serious interstitial lung disease, although this might depend on racial differences.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal gemcitabine-induced pulmonary toxicity in metastatic   gallbladder adenocarcinoma.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gemcitabine-induced pulmonary toxicity is usually a dramatic condition.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this report, we describe a fatal gemcitabine-induced pulmonary toxicity in a patient with gallbladder metastatic adenocarcinoma.",Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"He had hypokalemia (K 2.3 mmol/L) induced by licorice and also had received disopyramide for arrhythmia, bicalutamide for prostate cancer, and silodosin for prostate hypertrophy.",Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Therefore, although garenoxacin reportedly causes fewer adverse reactions for cardiac rhythms than third-generation quinolone antibiotics, one must be cautious of the interference of other drugs during hypokalemia in order to prevent TdP.",Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Torsades de Pointes induced by a combination of garenoxacin and disopyramide and other cytochrome P450, family 3, subfamily A polypeptide-4-influencing drugs during hypokalemia due to licorice.",Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report an 82-year-old man who developed ventricular tachycardia and Torsades de Pointes (TdP) after oral administration of garenoxacin, a novel quinolone antibiotic agent that differs from the third-generation quinolones, for pneumonia.",Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Of 371 patients treated with 8MOP, three (0.8%) developed an acute dermatitis in the PUVA-treated areas.",Dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity after high-dose methylprednisolone for demyelinating disease.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We observed 2 cases of hepatotoxicity after a high-dose methylprednisolone treatment of a demyelinating disease and evaluated the potential relationship in the light of available evidence.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Colonic mucosal necrosis following administration of calcium polystryrene sulfonate (Kalimate) in a uremic patient.,Mucosal necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Colonic necrosis is known as a rare complication following the administration of Kayexalate (sodium polystryrene sulfonate) in sorbitol.,Mucosal necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two days after administration of Kalimate enema, he had profuse hematochezia, and a sigmoidoscopy showed diffuse colonic mucosal necrosis in the rectum and sigmoid colon.",Mucosal necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a rare case of colonic mucosal necrosis following Kalimate (calcium polystryrene sulfonate), an analogue of Kayexalate without sorbitol in a 34-yr-old man.",Mucosal necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clozapine-induced tardive dyskinesia in schizophrenic patients taking clozapine as a first-line antipsychotic drug.,Tardive dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: These results suggest that clozapine may cause TD; however, the prevalence is low and the severity is relatively mild, with no or mild self-reported discomfort.",Discomfort
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, several case reports have suggested that clozapine could also cause TD.",Tardive dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: Clozapine causes few extrapyramidal symptoms and is recommended as a treatment drug for severe tardive dyskinesia (TD).,Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"All-trans retinoic acid-induced focal myositis, synovitis, and mononeuritis.",Focal myositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Here we report a patient with newly diagnosed acute promyelocytic leukemia who developed acute focal myositis, synovitis, and possible vasculitis, after receiving all-trans retinoic acid therapy.",Focal myositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: To assess the nature, incidence, and risk factors of retinopathy associated with pegylated interferon and ribavirin combination therapy in chronic hepatitis C patients.",Retinopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Significant ocular complications such as an irreversible decrease of visual acuity may develop in patients treated with pegylated interferon.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Retinopathy in hepatitis C patients due to combination therapy with pegylated interferon and ribavirin.,Retinopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Administration of cisplatin in three patients with carboplatin hypersensitivity: is skin testing useful?,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Hypersensitivity to carboplatin has been reported in up to 44% of patients receiving this antineoplastic agent, usually occurring after several courses of treatment.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prick tests and intradermal tests with a series of dilutions of carboplatin and cisplatin were performed on three patients who had exhibited medium and severe hypersensitivity reactions to carboplatin.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension in a patient treated with trimethoprim-sulfamethoxazole.",Meningitis aseptic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: A 37-year-old African- American man with G6PD deficiency developed hemolytic anemia, hepatitis, orthostatic hypotension, and aseptic meningitis simultaneously after using trimethoprim-sulfamethoxazole.",Meningitis aseptic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.",Speech disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"PURPOSE: The case of a patient who developed aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension simultaneously during treatment with trimethoprim-sulfamethoxazole is described.",Meningitis aseptic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient, while on intravenous ritodrine therapy for preterm labor, experienced an episode of acute chest pain.",Chest pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The electrocardiogram (ECG), which was read as normal prior to ritodrine infusion, demonstrated a type I second-degree AV block which disappeared upon discontinuation of ritodrine therapy.",Atrioventricular block second degree
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Type I second-degree AV block (Mobitz type I, Wenckebach AV block) during ritodrine therapy for preterm labor.",Atrioventricular block second degree
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Exacerbation of anthracycline-induced early chronic cardiomyopathy with ATRA: role of B-type natriuretic peptide as an indicator of cardiac dysfunction.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a 14-year-old female with acute promyelocytic leukemia who developed symptomatic cardiomyopathy only 4 months into treatment with a combination of daunomycin and all-trans retinoic acid (ATRA).,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: We present a case of a patient with CML who developed KS 12 months after starting treatment with imatinib 400 mg/d.,Kaposi's sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Flare of Kaposi's sarcoma (KS) is well described in immunosuppressed patients treated with corticosteroids and rituximab, but has not yet been reported during treatment with imatinib.",Kaposi's sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Kaposi's sarcoma in a patient treated with imatinib mesylate for chronic myeloid leukemia.,Kaposi's sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: We report a case of cutaneous KS lesions in a patient affected by CML treated with imatinib.,Kaposi's sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bulbar and pseudobulbar palsy complicating therapy with high-dose cytosine arabinoside in children with leukemia.,Bulbar palsy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Interferon-based treatments have the potential to decrease the burden of disease, but are complicated by side effects, including neuropsychiatric symptoms.",Neuropsychological symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Interferon-induced psychosis as a ""psychiatric contraindication"" to hepatitis C treatment: a review and case-based discussion.",Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHOD: The authors followed a patient with chronic HCV who received interferon and ribavirin and who developed hallucinations ultimately requiring psychiatric hospitalization.,Hallucination
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: The authors described a case of interferon-induced psychosis as a framework to review the literature and discuss the decision to pursue antiviral treatment in psychiatrically ill patients with hepatitis C.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Zidovudine is well a known cause of anaemia and thus should be used with caution in the initiation of antiretroviral therapy.,Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of Zidovudine induced anaemia and bone marrow aplasia in a patient infected with HIV.,Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Zidovudine induced pure red cell aplasia: a case report.,Aplasia pure red cell
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: SD-OCT and AO detected abnormalities that correlate topographically with visual field loss from hydroxychloroquine toxicity as demonstrated by HVF 10-2 and may be useful in the detection of subclinical abnormalities that precede symptoms or objective visual field loss.,Loss of visual contrast sensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To describe spectral-domain optical coherence tomography (SD-OCT) and adaptive optics (AO) imaging in hydroxychloroquine retinal toxicity.,Retinal toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Spectral-domain optical coherence tomography and adaptive optics may detect hydroxychloroquine retinal toxicity before symptomatic vision loss.,Retinal toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient trazodone-induced hypomanic symptoms occurred in three depressed patients.,Hypomania
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Trazodone-induced transient hypomanic symptoms and their management.,Hypomania
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Introduction of etanercept was also clinically effective but followed by development of severe heart failure.,Cardiac failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible heart failure in a patient receiving etanercept for ankylosing spondylitis.,Cardiac failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Combining methylephedrine and Chinese herbal drugs might carry a risk of stroke.,Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a patient who experienced chronic nausea and an episode of confusion while treated with a small, stable dose of oral morphine in the setting of mild renal insufficiency.",Nausea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Common adverse events (frequency 10%) of lacosamide doses up to 600 mg/day include nonspecific central nervous system effects (e.g., dizziness, ataxia, diplopia, and somnolence).",Ataxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of aseptic pleuropericarditis in a patient with chronic plaque psoriasis under methotrexate therapy.,Pleuropericarditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Methotrexate may rarely provoke serositis, even with low doses and after just a few weeks of therapy.",Serositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report here a rare case of pleuropericarditis due to methotrexate.,Pleuropericarditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors report five cases of tremor related to itraconazole therapy, which occurred within 1-12 months of initiating treatment and resolved gradually following itraconazole withdrawal.",Tremor
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tremor: a newly described adverse event with long-term itraconazole therapy.,Tremor
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypersensitivity to zonisamide was confirmed by the skin patch test.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of acute kidney injury due to zonisamide-induced DRESS/DIHS.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Only two case reports of adults with allergic contact dermatitis to this chemical exist in the literature, and we describe three more cases of children with recalcitrant atopic dermatitis found to have potential allergic contact dermatitis to bisabolol- a component of the Aquaphor emollient they were using to treat their atopic dermatitis.",Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case report: acute renal failure after administering intravenous immunoglobulin.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The hospital course of the acute renal failure is presented with a review of the literature on cases of acute renal failure after IVIG.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of an 87-year-old white woman with myasthenia gravis who presented with nausea, shortness of breath, azotemia, and hyperkalemia shortly after completing a course of intravenous immunoglobulin (IVIG).",Azotaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, the use of lithium should be avoided with any patient who is purging, since it may exacerbate the loss of intracellular potassium, thereby increasing the risk of cardiac toxicity.",Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe vancomycin-induced anaphylactic reaction.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Vancomycin is widely used against methicillin-resistant Staphylococcus aureus infections, but it is associated with many adverse effects such as nephrotoxicity, ototoxicity, gastrointestinal disturbances, blood disorders, and two types of hypersensitivity reactions - an anaphylactoid reaction known as ""red man syndrome"" and anaphylaxis.",Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of a 23-year-old man who developed a vancomycin-induced anaphylactic reaction in the treatment of methicillin-resistant Staphylococcus aureus infection.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Four patients in whom pulmonary oedema developed during tocolysis with hexoprenaline are described and the aetiological factors and pathogenesis of this potentially lethal complication discussed.,Pulmonary oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary oedema after hexoprenaline administration in preterm labour.,Pulmonary oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal interstitial lung disease after erlotinib administration in a patient with radiation fibrosis.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"High-resolution computed tomography scan findings were consistent with ILD, which was sufficient to diagnose as erlotinib-induced ILD.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"INTRODUCTION: Although gefitinib used for the treatment of non-small-cell lung cancer is a well-known cause of interstitial lung disease (ILD), few case reports on erlotinib-induced ILD have been issued.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: We recently experienced a case of fatal erlotinib-induced ILD, diagnosed based on clinical and radiologic findings, which occurred in a patient with radiation fibrosis.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case had radiation fibrosis, so we suggest that radiation fibrosis may be another contributor of the occurrence of ILD in patients taking erlotinib.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"One patient suffered coronary artery vasospasm, attributed to the use of topical 1:1000 epinephrine during surgery.",Arteriospasm coronary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The other patient developed transient intraoperative hypertension immediately after inadvertent submucosal injection of concentrated epinephrine.,Procedural hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cisplatin-induced syndrome of inappropriate antidiuretic hormone (SIADH) in a patient with neuroendocrine tumor of the cervix: a case report and review of the literature.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of the syndrome of inappropriate antidiuretic hormone (SIADH) secondary to cisplatin therapy in a patient with advanced-stage large cell neuroendocrine carcinoma of the cervix.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, to our knowledge, in newborns there have been no reported cases to date of thrombocytosis induced by enoxaparin.",Thrombocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombocytosis associated with enoxaparin: A very rare cause in newborns.,Thrombocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombocytosis induced by enoxaparin has been reported as a rare adverse effect of this medication in adults.,Thrombocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: 1) To describe a patient with rheumatoid arthritis receiving adalimumab who developed fever, pancytopenia, splenomegaly, and extreme hyperferritinemia.",Hyperferritinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Visceral leishmaniasis and macrophagic activation syndrome in a patient with rheumatoid arthritis under treatment with adalimumab.,Haemophagocytic lymphohistiocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case presentation is of a patient who had the clinical appearance of epiglottitis, but actually had an oro-pharyngeal dystonic reaction to prochlorperazine.",Epiglottitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Normalization of generalized retinal function and progression of maculopathy after cessation of therapy in a case of severe hydroxychloroquine retinopathy with 19 years follow-up.,Retinopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After other potential causes of liver toxicity were excluded, TMP-SMX was determined to be the cause of his acute liver toxicity.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although this combination agent has been associated with a hypersensitivity syndrome involving cutaneous skin eruptions, pediatric cases of TMP-SMX-induced hepatotoxicity are rare.",Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Due to the increasing use of TMP-SMX in children, clinicians should be aware of this potentially life-threatening, immunemediated hypersensitivity reaction.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Trimethoprim-sulfamethoxazole-induced hepatotoxicity in a pediatric patient.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Use of the Naranjo adverse drug reaction probability scale indicated a probable relationship (score of 5) between the patient's development of hepatotoxicity and the TMP-SMX therapy.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a relatively healthy, 9-year-old boy who developed a CA-MRSA skin and soft tissue infection and was treated with TMP-SMX.",Soft tissue infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Amiodarone was discontinued, and thyrotoxicosis gradually abated.",Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Goiter and hypothyroidism during re-treatment with amiodarone in a patient who previously experienced amiodarone-induced thyrotoxicosis.,Goiter
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: Aphthous stomatitis, a common mucocutaneous disorder, is a well accepted complication of sirolimus therapy.",Aphthous ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE: We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.,Aphthous ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe aphthous stomatitis associated with oral calcineurin and mTOR inhibitors.,Aphthous ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"These findings mean that the effect of the MP pulse therapy on renal function depends on the clinical state of the patient and that renal deterioration after the pulse therapy may be more marked in patients who are more nephrotic and more impaired in renal function and suggest that increasing sodium and water retention during an MP therapy and the associated renal interstitial edema, proposed as one of the mechanisms of acute renal failure occurring in patients with minimal-change nephrotic syndrome, may be responsible for the MP-induced transient renal failure.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three nephrotic patients who had reduced renal function and active renal disease with progressive deterioration of renal function prior to the use of MP developed transient renal failure following an MP pulse therapy.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 67-year-old patient, with primary polymyositis and without previous evidence of liver disease, developed clinical and biochemical features of severe cholestasis 3 months after initiation of azathioprine therapy.",Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is believed that this is the first reported case of reversible azathioprine-induced cholestasis associated with histological evidence of bile duct injury.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible cholestasis with bile duct injury following azathioprine therapy.,Abdominal injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of the Rett syndrome with acute encephalopathy induced during calcium hopantenate treatment.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a girl with the Rett syndrome who had acute encephalopathy probably induced by calcium hopantenate (HOPA).,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Persistent light reactivity from systemic quinine.,Photophobia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The photosensitivity is still present 3 years after the withdrawal of quinine.,Photosensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two cases are reported of patients who developed a hematologic malignancy several years after intravesical chemotherapy of superficial bladder cancer with etoglucid, doxorubicin, and mitomycin C.",Haematological malignancy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with Wegener's granulomatosis rapidly developed a circumferential subglottic stenosis while on a cyclophosphamide regimen that had caused resolution of systemic symptoms and pulmonary infiltrates.,Laryngeal stenosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Subglottic stenosis in Wegener's granulomatosis: development during cyclophosphamide treatment with response to carbon dioxide laser therapy.,Laryngeal stenosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case is described of severe splenic hemorrhage and rupture which developed 3 h after completion of tPA infusion for suspected acute myocardial infarction.,Splenic rupture
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Splenic hemorrhage: a complication of tissue plasminogen activator treatment.,Splenic haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombolytic therapy with tissue plasminogen activator (tPA) for acute myocardial infarction may result in major bleeding complications such as gastrointestinal or intracranial bleeding.,Haemorrhage intracranial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of severe acute hepatitis caused by cyproterone acetate in a 71 year old man with prostatic carcinoma is reported with a review of the literature on hepatic reactions to this drug.,Hepatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Monitoring of liver function tests should be mandatory in patients receiving high doses of cyproterone acetate; the drug should be withdrawn immediately if abnormal liver function tests are found.,Liver function test abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe hepatitis caused by cyproterone acetate.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A unique case of a transient, nonpigmenting fixed drug eruption caused by the radiopaque contrast medium iothalamate is reported.",Fixed eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One patient with systemic lupus erythematosus developed erythema multiforme after taking griseofulvin.,Erythema multiforme
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Aminoglutethimide was discontinued until completion of radiotherapy, and the rash resolved.",Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Concomitant irradiation apparently enhanced the skin toxicity of aminoglutethimide or possibly aminoglutethimide had a radiosensitizing role in this patient.,Skin toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of radiotherapy-enhanced aminoglutethimide skin toxicity in a patient with metastatic breast cancer.,Skin toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Data have been published regarding the possibility that tamoxifen may be responsible for the subsequent development of carcinoma of the corpus uteri in these patients.,Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors intend to carry out a case-control study on patients treated with tamoxifen for breast carcinoma to reveal the possible presence of endometrial carcinoma.,Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disulfiram-induced hepatitis.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Our patient had headache, mild fever, nausea, vomiting, rash, and eosinophilia after 3 weeks of disulfiram therapy.",Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We reported a case of disulfiram-induced hepatitis with unique clinical features and compared our case with others in the literature.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"An episode of leukoencephalopathy is reported in a 13-year-old girl who, after standard radiotherapy for a posterior fossa medulloblastoma, received 8 treatments with a protocol containing a 4-hour infusion of 500 mg/m2 methotrexate and 12 mg intrathecal methotrexate.",Leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate-induced leukoencephalopathy is treatable with high-dose folinic acid: a case report and analysis of the literature.,Leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe heparin associated thrombocytopenia is a rare complication of heparin therapy.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient who developed heparin associated thrombocytopenia during continuous arteriovenous haemofiltration and discuss its implications and alternative anticoagulant treatment.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An encephalopathy and cardiomyopathy developed in a seventeen-year-old girl with chemotherapy-induced renal failure while receiving an intravesical aluminum infusion for hemorrhagic cystitis.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 62-year-old woman who was being treated for squamous cell carcinoma of the head and neck developed a chemotherapy-related hemolytic-uremic syndrome during the second cycle of neoadjuvant chemotherapy consisting of cisplatin, bleomycin, and methotrexate.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Awareness of this route of intoxication might be important in patients in whom neurologic or psychiatric symptoms develop while large amounts of lidocaine cream are being used.,Neuropsychological symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nitrendipine-induced gingival hyperplasia.,Gingival hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nitrendipine is an experimental calcium channel blocking agent that also appears to cause the side effect of drug-induced gingival hyperplasia.,Gingival hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Physicians using this ""new"" drug must be aware of the potential danger of sulfonamide-induced injury to the urinary tract.",Urinary tract injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sulfadiazine crystalluria revisited.,Crystalluria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe two cases of sulfadiazine-induced crystalluria and renal failure in patients with acquired immunodeficiency syndrome, review the pertinent literature, and discuss the pathogenesis.",Crystalluria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Glaucoma secondary to epithelial downgrowth and 5-fluorouracil.,Glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of secondary glaucoma caused by epithelial downgrowth in which filtration surgery was performed with adjunctive use of subconjunctival 5-fluorouracil.,Glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Antacid and sucralfate-induced hypophosphatemic osteomalacia: a case report and review of the literature.,Hypophosphataemic osteomalacia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because of a hypersensitivity reaction, initial therapy with penicillin G and gentamicin was stopped and substituted with cefazolin.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prenatal cytomegalovirus (CMV) infection associated with severe brain damage was detected in an infant whose mother had been treated with prednisolone and azathioprine for systemic lupus erythematosus (SLE).,Brain injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute coronary events following cisplatin-based chemotherapy.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Six patients with no previous signs or symptoms suggestive of coronary artery disease developed acute coronary ischemia/infarction shortly after cis-diamine-dichloroplatinum II (cisplatin) -based chemotherapy.,Acute coronary syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bowel perforation associated with intraperitoneal chromic phosphate instillation.,Intestinal perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Delayed bowel injury is an infrequently observed complication of chromic phosphate administration.,Intestinal perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report presents a case of colon perforation which occurred 4 months after treatment with intraperitoneal chromic phosphate for stage IB ovarian papillary serous cystadenocarcinoma.,Large intestine perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Despite a response of the meningeal tumor the patient developed in the third week of MTX treatment a progressive visual loss and loss of consciousness which worsened during subsequent Ara-C treatment and led to death within 3 weeks.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 59-year-old woman with myasthenia gravis who received a large dose of pyridostigmine bromide developed postoperative psychosis and was diagnosed as having bromide intoxication.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bromide intoxication secondary to pyridostigmine bromide therapy.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge , this is the first reported case of bromide intoxication due to pyridostigmine bromide administration.",Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diazepam use by pregnant women can be associated with a later presentation of withdrawal symptoms in the neonate than that induced by the use of other drugs.,Drug withdrawal syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We conclude that neurosurgeons and neurologists should be aware of calcium antagonist--related ileus in patients treated with nimodipine.,Ileus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report on a patient with subarachnoid haemorrhage who developed an acute life-threatening pseudo-obstruction of the colon, a variant of adynamic ileus, while being treated with intravenous nimodipine.",Ileus paralytic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,After discontinuation of danazol the diabetes completely resolved.,Diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Insulin-dependent diabetes mellitus associated with danazol.,Type 1 diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Insulin-dependent diabetes mellitus developed in a young woman 8 weeks after the initiation of danazol for treatment of pelvic endometriosis.,Type 1 diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An 83-year-old man receiving glipizide 10 mg bid developed symptomatic hypoglycemia within three days of adding trimethoprim/sulfamethoxazole (TMP/SMX) to his regimen.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Symptomatic hypoglycemia secondary to a glipizide-trimethoprim/sulfamethoxazole drug interaction.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A sixty-year-old woman with advanced breast cancer, previously treated with cisplatin, developed an irreversible lethal renal failure with anuria, the day after 5 g/m2 bolus ifosfamide.",Anuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lethal anuria complicating high dose ifosfamide chemotherapy in a breast cancer patient with an impaired renal function.,Anuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We strongly suspect that this lethal anuria was mainly due to ifosfamide, occurring in a patient having received previous cisplatin chemotherapy and with poor kidney perfusion due to transient hypotension.",Anuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ciprofloxacin is one drug that has been reported to cause interstitial nephritis.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Renal toxicities have been reported in less than one percent of the patients receiving ciprofloxacin therapy.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Suspected ciprofloxacin-induced interstitial nephritis.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This article describes a patient with suspected ciprofloxacin-induced interstitial nephritis.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In a female with acute lymphoblastic leukemia, inadvertent doxorubicin administration intrathecally caused severe, life-threatening, acute encephalopathy with high-pressure hydrocephalus.",Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe acute encephalopathy following inadvertent intrathecal doxorubicin administration.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Phenobarbital hepatotoxicity in an 8-month-old infant.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe hepatotoxicity from phenobarbital occurred in an infant boy who had a complicated illness with chronic bilateral subdural hematomas and sepsis.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Skin rash began after 2 weeks of treatment, and signs of hepatocellular failure developed 3 weeks after phenobarbital had been started.",Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atenolol-induced pseudolymphoma.,Pseudolymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although tardive dyskinesia is a known adverse reaction of sustained treatment with traditional neuroleptic agents, it was only rarely reported in association with sulpiride, a selective D2-receptor antagonist.",Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tardive dyskinesia induced by sulpiride.,Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These cases indicate that sulpiride can cause tardive dyskinesia and that this drug should be administered with caution.,Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe six patients who developed tardive dyskinesia after treatment with sulpiride for depression or gastrointestinal symptoms.,Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with seropositive rheumatoid arthritis developed ascites while taking weekly doses of methotrexate (MTX).,Ascites
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatitis with bridging fibrosis and reversible hepatic insufficiency in a woman with rheumatoid arthritis taking methotrexate.,Fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the third report of reversible hepatic decompensation associated with prolonged MTX therapy in patients with rheumatoid arthritis.,Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Upon discontinuation of MTX, her ascites resolved, and her arthritis became more active.",Ascites
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although high-dose methotrexate has been shown to be useful in the treatment of primary osteogenic sarcoma, the tumoricidal effects of therapy appear to have caused a fatal rise in intracranial pressure.",Intracranial pressure increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with intracranial osteosarcoma that arose 16 years after radiation therapy for hereditary retinoblastoma developed fatal cerebral edema and brainstem herniation after she received a single dose of intravenous methotrexate.,Brain herniation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transtentorial herniation caused by an intracranial mass lesion following high-dose methotrexate.,Intracranial tumour haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fever, pulmonary infiltrates, and pleural effusion following acyclovir therapy for herpes zoster ophthalmicus.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Following the institution of intravenous therapy with acyclovir, the patient developed fever, hemoptysis, and a pleural friction rub.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The fever abated promptly following discontinuation of acyclovir, and radiographic abnormalities resolved over ten days.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, the syndrome of fever, pulmonary infiltrates, and pleural effusion following use of acyclovir has not been previously reported.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Quinine-induced hearing loss.,Deafness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sensorineural hearing loss due to quinine therapy for malaria has frequently been mentioned in the literature but has not been a subject of research during the last decades.,Deafness neurosensory
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The case of a 29-year-old man suffering from falciparum malaria disease who got a reversible hearing loss from quinine therapy is presented.,Deafness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The ototoxicity of quinine can accurately be studied with ultrahigh frequency audiometry (up to 20 kHz).,Ototoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Hemolytic uremic syndrome in a patient on cis-platinum, vinblastine and bleomycin.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of a 53-year-old man who developed acute pneumonitis after bleomycin and moderate oxygen administration is presented.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Autopsy findings were consistent with bleomycin and oxygen-induced pulmonary damage.,Traumatic lung injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bleomycin pneumonitis potentiated by oxygen administration.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Oxygen potentiation of bleomycin-induced pulmonary toxicity is discussed.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with the Wolff-Parkinson-White syndrome presented with incessant orthodromic atrioventricular tachycardia following initiation of procainamide therapy.,Supraventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Escape atrial complexes, which occurred following junctional premature complexes, failed to initiate tachycardia in the control state but tachycardia was always reinitiated by an identical escape sequence after procainamide.",Tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition, the tachycardia persisted and was repeatedly spontaneously reinitiated for prolonged periods after procainamide.",Tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Procainamide-induced incessant supraventricular tachycardia in the Wolff-Parkinson-White syndrome.,Supraventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The pro-arrhythmic effects of procainamide may be explained on the basis of both its vagolytic action on the atrioventricular node as well as by prolongation of refractoriness in the accessory pathway.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Multicentric hepatocellular carcinoma following phosphate diethylstilbestrol therapy for prostatic cancer.,Hepatocellular carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is a unique autopsy case of hepatocellular carcinoma closely related to diethylstilbestrol (DES) therapy for prostatic cancer.,Hepatocellular carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 52-year-old woman developed symmetric sensorimotor polyneuropathy and cerebellar syndrome after 24 months of amiodarone treatment.,Cerebellar syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Peripheral neuropathy and cerebellar syndrome associated with amiodarone therapy.,Cerebellar syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Life-threatening hyponatremia caused by vinblastine.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The most likely cause of such hyponatremic episode is vinblastine.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although this type of hyperpigmentation has been previously seen in patients with cancer who are receiving bleomycin, this is, to our knowledge, the first reported case of bleomycin-induced hyperpigmentation in an AIDS patient and should be added to the growing list of cutaneous eruptions seen in these patients.",Pigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of hyperpigmentation due to bleomycin treatment in a patient with acquired immune deficiency syndrome (AIDS).,Pigmentation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A typical case of dextran-40 associated acute renal failure is presented.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Renal failure associated with the use of dextran-40.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Several possible explanations of the mechanism of renal failure associated with the use of dextran-40 are discussed.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"While the mechanism of dextran-associated renal failure remains unsolved, plasma exchange seems to be effective therapy.",Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,MR findings in methotrexate-induced CNS abnormalities.,Nervous system disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 57-year-old man developed morphea while taking bromocriptine.,Morphoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Morphea after bromocriptine therapy.,Morphoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 35-year-old female with borderline lepromatous (BL) leprosy who suffered from dapsone-induced erythroderma is reported.,Dermatitis exfoliative generalised
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dapsone-induced erythroderma with Beau's lines.,Dermatitis exfoliative generalised
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Akathisia appeared to be a common side effect of fluoxetine and generally responded well to treatment with the beta-adrenergic antagonist propranolol, dose reduction, or both.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Five patients receiving fluoxetine for the treatment of obsessive compulsive disorder or major depression developed akathisia.,Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fluoxetine-induced akathisia: clinical and theoretical implications.,Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors suggest that fluoxetine-induced akathisia may be caused by serotonergically mediated inhibition of dopaminergic neurotransmission and that the pathophysiology of fluoxetine-induced akathisia and tricyclic antidepressant-induced ""jitteriness"" may be identical.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three patients who had experienced neuroleptic-induced akathisia in the past reported that the symptoms of fluoxetine-induced akathisia were identical, although somewhat milder.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Horner's syndrome and demyelinating peripheral neuropathy caused by high-dose cytosine arabinoside.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Peripheral nerve dysfunction is a potentially serious complication of high-dose cytosine arabinoside.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Peripheral nervous system disturbances caused by cytosine arabinoside have rarely been reported.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient with acute leukemia who developed Horner's syndrome and a severe demyelinating peripheral neuropathy leading to death after receiving high-dose cytosine arabinoside.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nail-changes induced by penicillamine.,Nail disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Peculiar nail-changes in a 70-year-old woman with rheumatoid arthritis occurring after approximately 1 year of penicillamine treatment are described.,Nail disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reinstitution of penicillamine treatment caused a recurrence thus proving a causal relationship between penicillamine and the described nail-changes.,Nail disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ibuprofen-induced meningitis: detection of intrathecal IgG synthesis and immune complexes.,Meningitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of ibuprofen-induced meningitis in an otherwise healthy individual.,Meningitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Metoclopramide-induced parkinsonism is not rare, and appropriate dose reduction in patients with renal failure will help reduce the incidence of this morbidity.",Parkinsonism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metoclopramide-induced parkinsonism.,Parkinsonism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Their parkinsonism improved on discontinuation of metoclopramide therapy.,Parkinsonism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We have reported six cases of metoclopramide-induced parkinsonism seen in consultation over a two-year period.,Parkinsonism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is suggested that the fatal stroke may have resulted from arterial spasm caused by ergotamine overdosage and possibly complicated by thrombosis.,Arterial spasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide.,Water intoxication
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clofazimine induced nail changes.,Nail disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These nail changes gradually disappeared when the dose of clofazimine was reduced.,Nail disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two cases of lepromatous leprosy with erythema nodosum leprosum who were on high doses of clofazimine, showed discoloration of nail plate, subungual hyperkeratosis and onycholysis.",Nail discoloration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Attenuation of asparaginase-induced hyperglycemia after substitution of the Erwinia carotovora for the Escherichia coli enzyme preparation.,Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of persistent late onset asthma following treatment with captopril.,Asthma late onset
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the first case of de novo asthma following treatment with the angiotensin converting enzyme (ACE) inhibitor captopril.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case report of a patient with probable cisplatin and bleomycin-induced TMA is presented.,Thrombotic microangiopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient with chronic myeloid leukaemia treated with busulphan for 4-5 years, developed signs of busulphan toxicity and portal hypertension with ascites, oesophageal varices and jaundice.",Ascites
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although a lot of amiodarone-induced torsades de pointe have been published, a review of all these cases and the underlying risk-factors has never been made.",Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amiodarone induced torsades de pointe.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report three cases of amiodarone-induced torsades de pointe.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The syndrome of irreversible lithium-effectuated neurotoxicity (SILENT).,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Long lasting respiratory depression induced by morphine-6-glucuronide?,Respiratory depression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of long lasting respiratory depression after intravenous administration of morphine to a 7 year old girl with haemolytic uraemic syndrome.,Respiratory depression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rifampin-associated thrombocytopenia secondary to poor compliance.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Rifampin can be associated with severe adverse effects such as hepatitis, acute renal failure, hemolytic anemia, and thrombocytopenia.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This article reports the occurrence of rifampin-associated thrombocytopenia in an indigent patient after a four-month lapse in therapy for pulmonary tuberculosis.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present the first case of WES in an infant born to a mother taking haloperidol during her pregnancy.,Withdrawal syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Withdrawal emergent syndrome in an infant associated with maternal haloperidol therapy.,Withdrawal syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This report describes two patients who developed acute myelocytic leukemia only after exposure to cyclophosphamide, methotrexate, and 5-fluorouracil adjuvant therapy.",Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ulcerative proctitis in juvenile systemic lupus erythematosus after ibuprofen treatment.,Ulcerative proctitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of ulcerative proctitis after ibuprofen treatment in a girl with juvenile systemic lupus erythematosus.,Ulcerative proctitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intravenous cytarabine and methotrexate appear to act synergistically to enhance the potential for central nervous system toxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present two children with acute lymphocytic leukemia who developed leukoencephalopathy following administration of a combination of intravenous ara = C and methotrexate during the consolidation phase of chemotherapy.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dexamethasone treatment of amiodarone-induced thyrotoxicosis (AIT) with or without persistent administration of the drug.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Treatment of amiodarone-induced thyrotoxicosis (AIT) with thionamide, lithium or radioactive iodine is ineffective.",Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute myelogenous leukemia in patients receiving chlorambucil as long-term adjuvant chemotherapy for stage II breast cancer.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After the chlorambucil was discontinued, the wbc count began to slowly rise and the patient developed clinical AML.",Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Panic anxiety after abrupt discontinuation of mianserin.,Panic attack
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This panic anxiety was not relieved by taking etizolam and flunitrazepam again, but subsided rapidly by the re-administration of mianserin 30 mg/day, and because of that the depressive symptom also disappeared.",Panic attack
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prior neurologic illness and the syndrome of irreversible lithium-effectuated neurotoxicity (SILENT).,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prior neurologic illness or CNS insult of any kind is known to increase the vulnerability to neurotoxicity of lithium.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors describe a patient with hemiparesis who developed the syndrome of irreversible lithium-effectuated neurotoxicity (SILENT) while being treated with lithium for a manic episode.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Abrupt, accidental withdrawal of trihexyphenidyl triggered severe exacerbation of the cranial dystonia associated with inspiratory stridor and acute respiratory difficulties, prompting emergency admission.",Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Life-threatening cranial dystonia following trihexyphenidyl withdrawal.,Torticollis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Administration of intrathecal Ara-C in the same dose over longer intervals within 3-5 days between consecutive doses resulted in mild, transient neurological symptoms (paresthesias) in only one of 30 patients so treated.",Paraesthesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Paraplegia following intrathecal cytosine arabinoside.,Paraplegia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Paraplegia following prophylactic intrathecal cytosine arabinoside (Ara-C) is described in a patient with acute myelogenous leukemia in remission who received doses of 100 mg/m2/d for 5 consecutive days.,Paraplegia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Both patients developed hypoadrenalism while on o,p'-DDD and apparently adequate dexamethasone replacement therapy.",Adrenal insufficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Alprazolam-induced mania: two clinical cases.,Mania
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors caution that treatment with alprazolam may be complicated by the induction of mania.,Mania
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients treated with alprazolam had histories suggestive of a bipolar disorder and developed lithium-responsive manic episodes.,Mania
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case is presented in which a 68-year-old man became delirious after being withdrawn from a low dosage of alprazolam.,Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Alprazolam withdrawal delirium unresponsive to diazepam: case report.,Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We discuss a variety of bronchopulmonary complications of IBD and their association with sulfasalazine.,Inflammatory bowel disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Administration of amantadine was associated with psychotic decompensations in two schizophrenic patients being maintained on concomitant neuroleptic medication.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Despite a postulated dopaminergic mechanism, there seems to have been only one previous report of amantadine's precipitating psychosis in a schizophrenic patient.",Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Exacerbation of schizophrenia associated with amantadine.,Schizophrenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Soon after its introduction in 1952, chlorpromazine was noted to induce symptoms resembling Parkinson's disease.",Parkinsonism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It is suggested that the patient had sulfasalazine-induced lupus, which manifested with serositis and pulmonary parenchymal involvement in the absence of joint symptoms.",Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Physicians who use sulfasalazine to treat patients with inflammatory bowel disease should be aware of the signs of sulfasalazine-induced lupus syndrome.,Systemic lupus erythematosus syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pneumonitis, bilateral pleural effusions, echocardiographic evidence of cardiac tamponade, and positive autoantibodies developed in a 43-year-old man, who was receiving long-term sulfasalazine therapy for chronic ulcerative colitis.",Pleural effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sulfasalazine-induced lupus erythematosus.,Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute myocardial infarction due to coronary spasm associated with L-thyroxine therapy.,Acute myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Electrocardiographic findings and laboratory data indicated a diagnosis of acute myocardial infarction due to the L-thyroxine therapy.,Acute myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We believe this is the first report of myocardial infarction due to coronary spasm, demonstrated by angiography associated with L-thyroxine therapy.",Arteriospasm coronary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A study of in vitro reactivity to L-T4, as assessed by peripheral blood lymphocyte transformation, was carried out in a patient with Hashimoto's disease who developed leukopenia during treatment with L-T4.",Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,L-Thyroxine-induced leukopenia in a patient with Hashimoto's disease: involvement of suppressor-cytotoxic T cells.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ampicillin-induced interstitial nephritis with generalised exfoliative dermatitis.,Dermatitis exfoliative generalised
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, there are few reports in the literature of ampicillin as a cause of acute interstitial nephritis.",Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the following case report, a patient developed acute interstitial nephritis with renal failure and exfoliative dermatitis following ampicillin therapy.",Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The diagnosis was based on the rapid onset of renal failure, presence of eosinophilia, skin rash, and characteristic renal biopsy finding, following the administration of ampicillin.",Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient receiving vancomycin for a serious staphylococcal infection had a lupus-like syndrome characterized by a malar rash, pain and erythema of the cartilage of both ears, and tender erythematous and hemorrhagic lesions of the finger tips.",Erythema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The possible development of a drug-induced vasculitis or lupus-like syndrome should be added to the list of rare toxic effects of vancomycin.,Lupus-like syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Vancomycin-induced vasculitis.,Vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Abnormal retinal function associated with isotretinoin therapy for acne.,Retinal function test abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three of 50 patients treated with isotretinoin (1 mg/kg/day) for cystic acne complained of poor night vision and/or excessive glare sensitivity.,Photophobia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ethambutol is frequently used in the treatment of tuberculosis, and, although optic neuropathies have been reported with the use of ethambutol, this adverse side effect has been considered to be rare and generally reversible with discontinuation of the medication.",Optic neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, we recently saw two patients with renal tuberculosis treated with ethambutol in whom visual loss from toxic optic neuropathies was severe and irreversible despite careful ophthalmological monitoring and prompt discontinuation of the agent at the first sign of impaired visual function.",Optic neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Optic neuropathy in ethambutol-treated renal tuberculosis.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since ethambutol is actively excreted via the renal system, compromise of renal function such as due to renal tuberculosis may lead to serum concentration elevations of ethambutol sufficient to produce optic neuropathy.",Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 57-year-old woman presented with a 3-week history of dysphagia for solids, 6 months after starting treatment with nifedipine.",Dysphagia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gastro-oesophageal reflux associated with nifedipine.,Gastrooesophageal reflux disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Nifedipine may induce, or aggravate, pre-existing, gastro-oesophageal reflux.",Gastrooesophageal reflux disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A young diamond dealer developed visual impairment attributed to bilateral posterior subcapsular cataracts following only four courses of intermittent Decadron used as part of a five-drug antiemetic regimen for cisplatin-associated nausea.,Cataract
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cataracts induced by intermittent Decadron used as an antiemetic.,Cataracts
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Recent reports have shown that Decadron (dexamethasone; Merck Sharp & Dohme, West Point, Pa) has a significant antiemetic effect on cisplatin-induced vomiting.",Vomiting
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient phenytoin induced IgA deficiency and permanent IgE increase.,Selective IgA immunodeficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The pharmacology and toxicology of chloral hydrate are discussed with particular reference to the cardiac arrhythmias that are seen with overdosage.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Adrenaline dacryolith: detection by ultrasound examination of the nasolacrimal duct.,Dacryolith
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Histological examination of the dacryolith suggested its derivation from breakdown products of adrenaline.,Dacryolith
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Possible pathophysiological mechanisms which may have been operative in this case include: a direct central nervous system (CNS) toxic effect of valproic acid; a paradoxical epileptogenic effect secondary to the drug; and an indirect CNS toxic effect mediated through valproic acid-induced hyperammonemia.,Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible valproic acid-induced dementia: a case report.,Dementia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible valproic acid-induced dementia was documented in a 21-year-old man with epilepsy who had a 3-year history of insidious progressive decline in global cognitive abilities documented by serial neuropsychological studies.,Dementia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Co-trimoxazole red cell aplasia in leukaemia.,Aplasia pure red cell
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,When co-trimoxazole was stopped the red cell aplasia resolved.,Aplasia pure red cell
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient developed optic neuropathy while being treated with isoniazid and ethambutol.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A well-recognized complication of ethambutol use is optic neuropathy, but the potential ocular toxicity of isoniazid is often overlooked.",Ocular toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Isoniazid and ethambutol as a cause of optic neuropathy.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A woman 38-year-old, suffering for about ten years from multiple sclerosis and treated with repeated therapy cycles of intrathecal Depo-Medrol, developed a spastic paraparesis at the lower limbs.",Paraparesis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A young woman with epilepsy had tonic-clonic seizures during antineoplastic therapy with adriamycin and cisplatin.,Generalised tonic-clonic seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hyperkalemia as a late side effect of prolonged adrenocorticotropic hormone therapy for infantile spasms.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two infants developed hyperkalemia shortly after cessation of prolonged ACTH therapy for infantile spasms.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We wish to call for cautious approach at time of cessation of prolonged ACTH therapy because of possible unexpected and only partially understood hazardous side effects such as hyperkalemia.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three patients, in whom tumour overkill by cytotoxic treatment, including high dose methotrexate with folinic acid rescue, resulted in the 'phosphate shower syndrome' (hyper-uricaemia, hyperkalaemia and hyperphosphataemia with hypocalcaemia and tetany, with metabolic acidosis and acute renal impairment) are described.",Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Accordingly, camptocormia is a dose-dependent side effect of valproate.",Camptocormia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Camptocormia, a new side effect of sodium valproate.",Camptocormia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Four weeks earlier she had developed hepatopathy during a regimen of carbamazepine, lynestrenol and sodium valproate.",Liver disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatopathy subsided after the cessation of carbamazepine and lynestrenol.,Liver disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 10-year-old girl with Lennox-Gastaut syndrome who received intravenous lorazepam for atypical absence status seizures is reported.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Paradoxical precipitation of tonic seizures by lorazepam in a child with atypical absence seizures.,Tonic convulsion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atrial fibrillation following methylprednisolone pulse therapy.,Atrial fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Isotretinoin, a drug used for the treatment of acne, has been shown to have teratogenic effects.",Teratogenicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Isotretinoin teratogenicity.,Teratogenicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case of allopurinol hypersensitivity, possibly the first in a black African, is reported.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Allopurinol hypersensitivity.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The allopurinol hypersensitivity syndrome is a rare adverse drug reaction.,Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bone formation induced in an infant by systemic prostaglandin-E2 administration.,Bone formation increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of severe visual loss following a single dose of vincristine is described.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Although differential diagnostic alternatives can be considered in all described cases it is very likely that vincristine does cause severe visual loss in a small number of patients.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe visual loss after a single dose of vincristine in a patient with spinal cord astrocytoma.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The literature of vincristine optic nerve toxicity is reviewed.,Optic neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Visual loss after a single small dose of vincristine has never been reported.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Niacin causes a reversible toxic cystoid maculopathy that occurs in approximately 0.67% of patients taking high doses of the drug.,Cystoid macular oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Niacin maculopathy.,Maculopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors conclude that among patients taking high doses of oral niacin only those who experience visual symptoms need to be ophthalmologically evaluated.,Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three patients with niacin-induced visual symptoms had cystoid maculopathy without leakage on fluorescein angiography, and a fourth patient with no fundus abnormality experienced cessation of visual symptoms upon discontinuation of niacin.",Cystoid macular oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case report of the hypersensitivity syndrome occurring in a patient being treated with dapsone for a brown recluse spider bite is presented.,Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case report: dapsone hypersensitivity syndrome associated with treatment of the bite of a brown recluse spider.,Hypersensitivity syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rifampicin-induced adrenal insufficiency in the acquired immunodeficiency syndrome: difficulties in diagnosis and treatment.,Adrenal insufficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a patient with the acquired immunodeficiency syndrome treated with rifampicin who had a 'normal' screening test for adrenal insufficiency, yet had clinical evidence of adrenal failure.",Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two cases of widespread cutaneous vasculitis are described in association with diltiazem, a recently introduced calcium antagonist.",Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Widespread cutaneous vasculitis associated with diltiazem.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intraventricular nafcillin-induced seizures in a neonate.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a premature infant who developed seizures associated with intraventricular administration of nafcillin and discuss the need for electroencephalographic monitoring of patients receiving intraventricular antibiotics.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 58-year old patient is reported who developed an ischaemic cerebrovascular accident 22 hours after successful thrombolysis with streptokinase for life-threatening pulmonary emboli.,Ischaemic stroke
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombo-embolic complication after streptokinase therapy of pulmonary emboli.,Embolism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Renal hypophosphatemia in this patient was caused by the erroneous intake of 1 g doxycycline.,Hypophosphataemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A clinically atypical, neuropathologically verified case of Creutzfeldt-Jakob disease is described in a 32-year-old New Zealand woman with idiopathic hypopituitarism who had been treated in late adolescence (1970 to 1973) with human growth hormone processed from pooled cadaveric pituitary glands.",Creutzfeldt-Jakob disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A new case of Creutzfeldt-Jakob disease associated with human growth hormone therapy in New Zealand.,Creutzfeldt-Jakob disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of a 21-year-old woman who had developed mild hepatotoxicity while receiving choline magnesium trisalicylate therapy is described.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity associated with choline magnesium trisalicylate: case report and review of salicylate-induced hepatotoxicity.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Salicylate-induced hepatotoxicity is reviewed.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,They continued to rise for five more days before salicylate hepatotoxicity was suspected.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 51-yr-old nonsmoking male patient without any history of previous allergies, asthma, hay fever, or urticaria developed attacks of asthma when captopril was added to the nadolol and dyazide treatment for his high blood pressure.",Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Captopril-related (and -induced?) asthma.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This confirmed the history of captopril-related asthma.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We also describe a case of timolol-induced ocular pemphigoid.,Ocular pemphigoid
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The observations suggest that testicular swelling and pain are side effects of desipramine.,Pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients are described who developed testicular swelling and pain during treatment with desipramine.,Pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Benzocaine, an ester-type local anesthetic, was believed responsible for apparent methemoglobinemia in a cat.",Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Benzocaine-induced methemoglobinemia has been reported in man, dogs, and cats.",Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methemoglobinemia associated with dermal application of benzocaine cream in a cat.,Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 43-year-old white man developed a shallow erosion of a psoriatic plaque after chronic administration of methotrexate.,Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Erosion of psoriatic plaques after chronic methotrexate administration.,Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Unexpected severe reversible cyclosporine A-induced nephrotoxicity in a patient with systemic lupus erythematosus and tubulointerstitial renal disease.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient is presented with typical hyperthyroidism, who developed a severe proximal muscle weakness and a raised creatine phosphokinase after treatment for hyperthyroidism with propylthiouracil (100 mg orally, three times a day).",Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Polymyositis after propylthiouracil treatment for hyperthyroidism.,Polymyositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiopulmonary arrest following intravenous phenytoin loading.,Cardio-respiratory arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Evidence obtained indicated that the Reye-like syndrome might be caused by calcium hopantenate possibly due to the induction of pantothenic acid deficiency.,Pantothenic acid deficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Reye-like syndrome following treatment with the pantothenic acid antagonist, calcium hopantenate.",Reye's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three senile patients developed fatal acute encephalopathy while receiving calcium hopantenate.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dyspnea possibly associated with controlled-release morphine sulfate tablets.,Dyspnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anhedonic ejaculation with desipramine.,Ejaculation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two patients with anhedonic ejaculation (ejaculation without orgasm) associated with initiation of treatment with desipramine.,Ejaculation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myoclonic spasms following intrathecal morphine.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of halothane induced hepatitis is reported in a middle aged woman who underwent gastric surgery for morbid obesity.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Halothane hepatitis and prompt resolution with methionine therapy: case report.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of porphyria cutanea tarda after treatment with cyclophosphamide.,Porphyria non-acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 46-yr-old woman with ovarian carcinoma who developed porphyria cutanea tarda while undergoing treatment with cisplatin and cyclophosphamide.,Porphyria non-acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure in a patient treated by continuous povidone-iodine mediastinal irrigation.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a 63 year old woman with a suppurative mediastinitis, treated with continuous PI irrigation who developed an acute oliguric renal failure.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,D-penicillamine induced crescentic glomerulonephritis: report and review of the literature.,Glomerulonephritis rapidly progressive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The 9 other reported cases of D-penicillamine induced rapidly progressive glomerulonephritis have been reviewed.,Glomerulonephritis rapidly progressive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gold-induced pneumonitis is a rare complication of gold salt therapy.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gold-induced pneumonitis.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case supports the view that in gold-induced pneumonitis a prolonged treatment with corticosteroids may be necessary, as lung function continued to improve.",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a patient with rheumatoid arthritis treated with gold salts, who developed bilateral interstitial pulmonary abnormalities and showed a dramatic response on corticosteroid therapy.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gold-induced aplastic anemia.,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three patients receiving gold salt treatment for rheumatoid arthritis developed severe aplastic anemia.,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pharmacokinetic determinants of 6-mercaptopurine myelotoxicity and therapeutic failure in children with acute lymphoblastic leukemia.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because the cerebellar toxicity may be worsened by continuation of therapy after initial onset of symptoms, prompt termination of HDARAC is recommended.",Spinocerebellar disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cytarabine-induced cerebellar syndrome: case report and literature review.,Spinocerebellar disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"During the first treatment, dysarthria and ataxia were seen after completion of the patient's eighth and final dose of HDARAC.",Ataxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The neurotoxicity seen with HDARAC is dose-related and has occurred in up to 60 percent of treated patients.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case report illustrates the neurotoxicity unique to HDARAC.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Macular infarction after endophthalmitis treated with vitrectomy and intravitreal gentamicin.,Macular ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A woman with a 20-year history of acral pustular psoriasis of Hallopeau and recurrent pustular lesions of the forearms and lower legs, developed a B-cell lymphoma of the lip following 4 1/2 years of treatment with razoxane.",B-cell lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Extensive immunological investigations were performed in a patient with definite seronegative rheumatoid arthritis who developed hypogammaglobulinemia in the course of gold therapy.,Hypogammaglobulinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypogammaglobulinemia associated with gold therapy: evidence for a partial maturation blockade of B cells.,Hypogammaglobulinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient leucopenia and thrombocytopenia associated with sodium nitroprusside infusion.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Herpes simplex esophagitis in a renal transplant patient treated with cyclosporine A: a case report.,Herpes simplex oesophagitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of herpes esophagitis in a renal transplant patient treated with Cyclosporine A while on chronic steroid therapy.,Herpes oesophagitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"With the increasing use of Cyclosporine A in transplant patients, the incidence of herpes esophagitis may increase.",Herpes oesophagitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Administration of excessive insulin induced hypoglycemia within 4 to 8 hours, followed by rebound hyperglycemia.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Posthypoglycemic hyperglycemia (rebound hyperglycemia) after overdosing of insulin was diagnosed in 6 cats with diabetes mellitus.,Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rebound hyperglycemia following overdosing of insulin in cats with diabetes mellitus.,Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Rebound hyperglycemia was observed with both intermediate (neutral protamine hagedorn) and long-acting (protamine zinc iletin) insulins, and the range of insulin doses at which the disorder developed overlapped previously determined therapeutic doses for these insulins in the cat.",Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Captopril-induced lichen planus pemphigoides with pemphigus-like features.,Lichen planus pemphigoides
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of a bullous lichenoid eruption due to the intake of captopril.,Lichenoid keratosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"An 8-year-old girl, who had been vaccinated with BCG without subsequent regional reactions, developed osteomyelitis in the left calcaneus 7 months later.",Osteomyelitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metastatic osteomyelitis following BCG vaccination.,Metastatic bone disease prophylaxis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One of the subjects who was using extemporaneous topical minoxidil had hypertension and arteriosclerotic disease and the other died of a myocardial infarction.,Arteriosclerosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amoxapine-induced cognitive impairment in two patients.,Cognitive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients are described in whom subtle cognitive impairments are associated with therapeutic doses of amoxapine.,Cognitive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 23-year-old woman with systemic lupus erythematosus had a severe hypersensitivity reaction to the drug ibuprofen.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe systemic hypersensitivity reaction to ibuprofen occurring after prolonged therapy.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A brief review of reported cases of chloramphenicol hypersensitivity in the English-language literature, as well as possible alternative explanations in this case, are provided.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypersensitivity reaction following chloramphenicol administration in a patient with typhoid fever.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypersensitivity reactions due to chloramphenicol are rarely reported in the literature.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case report of a patient with typhoid fever who experienced a hypersensitivity reaction subsequent to the infusion of chloramphenicol sodium succinate.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Replicate brain magnetic resonance imaging examinations after six weeks and 11 months of penicillamine therapy documented the development of new brain lesions during this period, while liver biopsy specimen data disclosed that excellent hepatic decoppering had occurred.",Central nervous system lesion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a patient with Wilson's disease who presented with neurologic disease, was treated with D-penicillamine, and suffered sudden neurologic deterioration coincident with therapy.",Neurological decompensation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Other upper tract neoplasms after cyclophosphamide are reviewed.,Malignant respiratory tract neoplasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Upper tract urothelial malignancy after cyclophosphamide therapy: a case report and literature review.,Transitional cell carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report an unusual case of simultaneous transitional cell carcinoma of the renal pelvis and distal ureter without transitional cell carcinoma of the bladder occurring after chronic cyclophosphamide therapy for nonHodgkin's lymphoma.,Ureteral neoplasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Progressive pulmonary fibrosis complicating cyclophosphamide therapy.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The changes were progressive regardless of discontinuation of cyclophosphamide and led to severe restrictive ventilatory defect.,Restrictive pulmonary disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Torsade de pointes during loading with amiodarone.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Torsade de pointes represents a potential complication of chronic amiodarone therapy.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of torsade de pointes following a single oral dose of amiodarone (1400 mg or 30 mg kg-1) administered after short intravenous loading for prevention of paroxysmal atrial flutter.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary edema as a delayed complication of ritodrine therapy.,Pulmonary Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary edema occurred 24 hours after intravenous ritodrine therapy and 10 hours after subcutaneous terbutaline therapy.,Pulmonary Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Cyclosporin side effects included hirsutism, hypertension, increased blood levels of urea and creatinine, and abnormalities in liver function tests.",Liver function test abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rupture of a cerebral aneurysm associated with nifedipine treatment.,Ruptured cerebral aneurysm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe rupture of a cerebral arterial aneurysm in a 32 year old hypertensive woman following the introduction of nifedipine treatment.,Ruptured cerebral aneurysm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A small initial dose of prazosin ranging from 0.5 to 1 mg has been recommended to avoid the first-dose phenomenon characterized by a sudden and severe drop in blood pressure after the administration of the first dose of prazosin.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prazosin-induced first-dose phenomenon possibly associated with hemorrhagic stroke: a report of three cases.,Haemorrhagic stroke
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A fatal massive pulmonary embolus developed in a patient treated with streptokinase for acute deep vein thrombosis.,Pulmonary embolism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Massive pulmonary embolism complicating streptokinase treatment for deep vein thrombosis.,Pulmonary embolism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal digoxin poisoning: an unsuccessful resuscitation with use of digoxin-immune Fab.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case of phenytoin-induced hepatitis with mononucleosis is reported, and syndromes associated with phenytoin hypersensitivity reactions are discussed.",Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Phenytoin-induced hypersensitivity reactions.,Hypersensitivity reactions
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Phenytoin was discontinued after admission; however, phenytoin 1 g i.v. was given for a tonic-clonic seizure two days after admission, after which swelling of the face and legs and pruritus developed.",Pruritus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She was receiving phenytoin sodium 300 mg/day; carbamazepine 200 mg four times daily had been discontinued four days before admission because of leukopenia.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The possibility of phenytoin hypersensitivity reactions should be considered when patients receiving phenytoin have unusual symptoms, particularly fever, rash, and lymphadenopathy.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It was restarted 6 weeks later, and 10 weeks after that, the patient presented with fulminant hepatic failure, which resolved rapidly after cessation of nicotinic acid therapy.",Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nicotinic acid-induced fulminant hepatic failure.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We suggest that nicotinic acid was the cause of his liver disease, that this case is of particular note because of the rather short period of therapy before the onset of liver injury and the severity of the hepatic failure, and that the probable increased use of nicotinic acid for serum cholesterol control makes it especially important for physicians and their patients to be alert to the signs of hepatotoxicity.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"An infant girl with choanal atresia, athelia, minor anomalies, and mild to moderate mental retardation was born to a woman treated for hyperthyroidism throughout pregnancy with methimazole and propranolol.",Athelia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Choanal atresia and athelia: methimazole teratogenicity or a new syndrome?,Athelia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient's defects may be due to methimazole teratogenicity or could represent a previously undescribed syndrome affecting ectodermal structures.,Teratogenicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Toxic epidermal necrolysis resulted after 19 days of treatment with 5-fluorocytosine and amphotericin B.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Five and one-half years after the diagnosis of myeloma, while in remission on cyclophosphamide therapy, the patient experienced severe abdominal right lower quadrant pain due to a large cecal lymphoma.",Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After therapy with parenteral amiodarone (2300 mg in 3 days) and other measures, signs of congestive heart failure disappeared; subsequently the patient developed jaundice, marked increase in serum transaminase levels and fall in prothrombin time, and histologic changes of severe centrilobular necrosis were observed in hepatic biopsy.",Prothrombin time shortened
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with acute changes suggesting acute hepatitis after parenteral amiodarone administration is described.,Hepatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Probable early acute hepatitis with parenteral amiodarone.,Hepatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Therefore, parenteral amiodarone was implicated as the cause of acute hepatitis in this patient.",Hepatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,He became hyperkalemic on rechallenge with timolol and normokalemic following its withdrawal.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Severe hyperkalemia as a complication of timolol, a topically applied beta-adrenergic antagonist.",Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe hyperkalemia occurred in a patient with radiation pneumonitis and glaucoma shortly after beginning prednisone therapy.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Noncardiogenic pulmonary edema during intrabiliary infusion of mono-octanoin.,Non-cardiogenic pulmonary oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient in whom noncardiogenic pulmonary edema developed during intrabiliary infusion of monooctanoin.,Non-cardiogenic pulmonary oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Paroxysmal supraventricular tachycardia during treatment with cisplatin and etoposide combination.,Supraventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of a 60-year-old woman affected by squamous lung carcinoma, who developed paroxysmal supraventricular tachycardia during cisplatin and etoposide combination chemotherapy.",Supraventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case is reported of theophylline intoxication due to a dramatic decrease in theophylline clearance following concomitant administration of viloxazine.,Drug clearance decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Theophylline intoxication following viloxazine induced decrease in clearance.,Drug clearance decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Idiosyncratic pulmonary reactions to nitrofurantoin are not unusual, often presenting as eosinophilic pneumonia.",Eosinophilic pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute myocardial necrosis during administration of amsacrine.,Myocardial necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition to the recognized arrhythmic complications, the authors emphasize myocardial necrosis as a possible further manifestation of amsacrine-related cardiotoxicity.",Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors report a case of focal myocardial necrosis, presenting clinically as an acute myocardial infarction during the administration of the antineoplastic drug, amsacrine, in a patient without coronary artery disease.",Acute myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A child in whom a phenobarbital hypersensitivity drug reaction developed which consisted of fever, a pruritic desquamating erythrodermic rash, alopecia, icterus, protein-losing enteropathy, myositis, and nephritis, is described.",Alopecia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Graft versus host-like illness in a child with phenobarbital hypersensitivity.,Graft versus host disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The clinical findings and laboratory studies suggested an autoimmune cell-mediated hypersensitivity reaction triggered by phenobarbital.,Autoimmune disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Duodenal ulceration: a complication of tolazoline therapy.,Duodenal ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients who were receiving Tolazoline by infusion developed duodenal ulceration and subsequent intestinal perforation.,Duodenal ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The latter form (Macrodantin) is reported to engender less gastrointestinal intolerance but it can produce the same adverse effects as the conventional form--liver damage, acute and chronic pulmonary reactions, peripheral neuropathy, blood dyscrasias and allergic reactions--and does so just as rapidly and floridly; one such case is reported here.",Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Generalized pustular psoriasis precipitated by trazodone in the treatment of depression.,Pustular psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a patient in whom the anti-depressant trazodone hydrochloride (Molipaxin, Roussel), a serotonin antagonist, provoked generalized pustular psoriasis (GPP).",Pustular psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Intravenous verapamil therapy in babies may cause apnea, hypotension, and bradycardia; continued episodes of atrial flutter in a child may cause sudden death; quinidine may be related to the death; children with ""familial seizure disorders"" may in fact have the long QT interval syndrome.",Apnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methimazole-associated cholestatic liver injury: case report and brief literature review.,Cholestatic liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report a further case of methimazole-associated liver damage and present a brief review of eleven previous cases found in the literature.,Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The main clinical features of this 58-year-old female patient were laboratory evidence of leucopenia and cholestasis, and biopsy features of fatty liver parenchyma degeneration with granulocytic portal infiltration and bile stasis, demonstrated 20 days after the initiation of antithyroid therapy with 20 mg methimazole daily.",Biliary obstruction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 57-year-old woman developed pulmonary sarcoidosis during therapy with interferon beta for advanced renal cell carcinoma metastatic to mediastinal lymph nodes.,Pulmonary sarcoidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The possible role of interferon beta in the pathogenesis of sarcoidosis in this patient is discussed.,Sarcoidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fatal outcome of intravesical formalin instillation, with changes mimicking renal tuberculosis.",Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present a case report of a patient with alveolar hydatid disease, whose treatment with mebendazole was brief due to side effects of alopecia and granulocytopenia; and review the features of this disease which, with increasing international migration, may be encountered more frequently in Australia.",Alopecia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Antibiotic-associated colitis (pseudomembranous colitis) developed in four patients with spinal cord injury and taking oral trimethoprim-sulfamethoxazole.,Colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pseudomembranous colitis readily occurs in at least certain population groups receiving trimethoprim-sulfamethoxazole.,Pseudomembranous colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The condition should be suspected in patients who develop unexplained abdominal pain or collapse following vasopressin treatment.,Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although adverse reactions to protamine are reported infrequently and are usually mild, we recently observed the first fatal case of type I anaphylaxis resulting from protamine.",Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Protamine-induced fatal anaphylaxis.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ototoxicity as a result of cis-platinum administration is well documented.,Ototoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Controversy concerning the nephrotoxicity of lithium is discussed, and recommendations for the evaluation of renal failure during lithium therapy are provided.",Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atrioventricular block complicating amiodarone-induced hypothyroidism in a patient with pre-excitation and rate-dependent bilateral bundle branch block.,Atrioventricular block
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Such a case induced by hypothyroidism complicating long-term therapy with amiodarone in a 45 year old woman with pre-excitation is presented.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ampicillin may aggravate clinical and experimental myasthenia gravis.,Myasthenia gravis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myasthenic patients receiving ampicillin should be closely monitored for possible acute exacerbations.,Bronchitis haemophilus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One patient had severe temporary weakness after an ampicillin sodium challenge.,Muscular weakness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A study following large patient groups on theophylline and a combination of theophylline and steroids might clarify the risk of ulcer formation in patients being treated with these medications for asthma.,Ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We presented a patient with status asthmaticus treated with a combination of theophylline and prednisone who developed a perforated gastric ulcer.,Gastric ulcer perforation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of propranolol overdose complicated by esophageal spasm preventing extrication of an orogastric lavage tube and relieved by intravenous glucagon is presented.,Oesophageal spasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Esophageal spasm following propranolol overdose relieved by glucagon.,Oesophageal spasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypotension and sinus arrest with nifedipine in pulmonary hypertension.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient presented with a painful, oedematous, cyanosed hand having injected a solution of diamorphine and methylphenidate into his radial artery.",Oedema peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ischaemia following selfadministered intra-arterial injection of methylphenidate and diamorphine.,Ischaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chronic photosensitivity associated with hydrochlorothiazide ingestion occurred in four patients.,Photosensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiac decompensation following verapamil therapy in infants with supraventricular tachycardia.,Cardiac failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, each infant demonstrated hemodynamic decompensation shortly after verapamil administration and required cardiopulmonary resuscitation.",Haemodynamic instability
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The risk of cardiac decompensation in infants with supraventricular tachycardia and congestive cardiac failure should be kept in mind prior to administration of verapamil.,Cardiac failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pneumonitis with pleural and pericardial effusion and neuropathy during amiodarone therapy.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Review of this and previously reported cases indicates the need for early diagnosis of amiodarone pneumonitis, immediate withdrawal of amiodarone, and prompt but continued steroid therapy to ensure full recovery.",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Heparin-induced hyperkalemia.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Our findings suggest that hyperkalemia can develop with the use of low-dose heparin, within seven days of initiating heparin therapy, and that patients with diabetes mellitus or chronic renal insufficiency are especially predisposed to this complication.",Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present four cases in which the use of heparin was associated with hyperkalemia and discuss the pathophysiology.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"While most physicians are aware of heparin-induced thrombocytopenia and skin necrosis, the association of heparin and hyperkalemia is less well recognized.",Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Careful follow-up of so-called ""self-limited"" insulin edema is encouraged, and the early institution of diuretic therapy is advocated in elderly patients to prevent the development of overt cardiac failure.",Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Insulin-induced cardiac failure.,Cardiac failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Self-limited edema is a well-recognized complication of insulin therapy.,Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report describes the first case of insulin-induced cardiac failure in a patient without underlying heart disease.,Cardiac failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of pyridoxine-dependent seizures is reported.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Administration of pyridoxine to an infant after a long period of convulsions was followed by acute hypotonia.,Hypotonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prolonged severe cholestasis induced by oxacillin derivatives.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients with osteomyelitis who developed reversible cholestatic jaundice during treatment with oxacillin derivatives are described.,Jaundice cholestatic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In all the patients, pellagra symptoms appeared during isoniazid therapy.",Nicotinic acid deficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Isoniazid inhibits the conversion of tryptophan to niacin and may induce pellagra, particularly in poorly nourished patients.",Nicotinic acid deficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pellagra encephalopathy among tuberculous patients: its relation to isoniazid therapy.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pellagra should be suspected whenever tuberculous patients under treatment with isoniazid develop mental, neurological or gastrointestinal symptoms, even in the absence of typical pellagra dermatitis.",Gastrointestinal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Physicians should be aware of the potential for the development of RS among children who are receiving long-term aspirin therapy for the treatment of systemic inflammatory illnesses.,Reye's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reye syndrome (RS) is believed to occur infrequently among children receiving long-term aspirin therapy.,Reye's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These findings support previous studies that showed that the use of aspirin during the antecedent illness may be a risk factor for the development of RS.,Reye's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atrial fibrillation was induced by diltiazem in two patients and verapamil induced syncope in one patient.,Atrial fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 54-year-old man, treated with amiodarone, developed thyrotoxicosis.",Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"IV propranolol was used as the initial treatment for his hyperadrenergic state, resulting in a decrease in heart rate but a paroxsymal increase in blood pressure.",Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propranolol-induced hypertension in treatment of cocaine intoxication.,Hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"According to the literature, chlorambucil central nervous toxicity is found almost exclusively in childhood nephrotic syndrome.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,EEG abnormalities were observed in two of the nine children during chlorambucil therapy.,Electroencephalogram abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 35-year-old man with seropositive rheumatoid arthritis developed selective IgA deficiency during treatment with fenclofenac.,Selective IgA immunodeficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fenclofenac-induced selective IgA deficiency in rheumatoid arthritis.,Selective IgA immunodeficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case demonstrates the association of selective IgA deficiency with remission in rheumatoid arthritis induced by fenclofenac as well as aurothiomalate and sulphasalazine.,Selective IgA immunodeficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 65-year-old woman with bipolar disorder and complicated cardiovascular disease who was on maintenance lithium therapy developed a movement disorder following high doses of trazodone for treatment of an acute depression.,Movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although the movement disorder could not with certainty be attributed to trazodone alone, the drug at least acted as an eliciting agent.",Movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The elicitation of a movement disorder by trazodone: case report.,Movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When the trazodone was reduced, the involuntary movements promptly ceased.",Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A review of the literature showed no previous description of this pattern in benzodiazepine coma.,Coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Spindle coma in benzodiazepine toxicity: case report.,Spindle cell sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two reports of spindle coma are noted with alcohol and imipramine.,Spindle cell sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A literature review revealed 83 other reported cases of rifampicin-induced renal insufficiency.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Renal failure is a rare complication associated with the use of rifampicin for the treatment of tuberculosis, usually occurring well into the course of therapy.",Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rifampicin-induced renal failure.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The following is a report of 2 cases of rifampicin-induced renal insufficiency.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two of these patients, who also received the anti-emetic prochlorperazine, lost consciousness for 48-72 h and then fully recovered.",Loss of consciousness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two other patients who did not receive prochlorperazine, developed retinal problems which later improved, one after only 15 g of desferrioxamine.",Retinal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gold nephropathy: tissue analysis by X-ray fluorescent spectroscopy.,Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"These findings are consistent with an immune-complex form of glomerulopathy in which gold is neither the antigen nor a hapten in the glomerular deposits, and they suggest the hypothesis that antibodies to tubular epithelial antigens induced by gold therapy may be a causative factor in the renal disease associated with gold therapy in rheumatoid arthritis.",Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three patients developed proteinuria following gold therapy for rheumatoid arthritis.,Proteinuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Four cases of fat embolism are described in infants receiving prolonged intravenous infusion of fat (Intralipid 20%).,Fat embolism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Conversely, diffuse interstitial pulmonary fibrosis should be considered in the differential diagnosis of patients receiving methotrexate who develop bilateral pulmonary infiltrates seen on chest roentgenograms.",Lung infiltration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In all three cases, autopsy revealed gross and microscopic features indistinguishable from those seen in the Hamman-Rich syndrome, and methotrexate hepatotoxicity was present in one.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is suggested therefore that methotrexate be added to the list of agents capable of inducing diffuse interstitial pulmonary fibrosis.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate-induced diffuse interstitial pulmonary fibrosis.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pulmonary eosinophilia or granulomas, classically seen in previously reported cases of methotrexate pneumonitis, were not observed.",Granuloma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three patients received respectively 190 mg, 175 mg, and 196 mg of methotrexate and developed bilateral pulmonary infiltrates without evidence of peripheral blood eosinophilia.",Lung infiltration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with disseminated herpes zoster developed a syndrome of inappropriate antidiuretic hormone and profound hyponatremia secondary to the administration of adenine arabinoside.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Inappropriate antidiuretic hormone following adenine arabinoside administration.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The toxic effects of methotrexate included elevated liver transaminases (3/4), nausea (2/4), abdominal pain (2/4), bone pain (2/4), mild neutropenia (1/4), and mild pruritus (1/4).",Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dystonia associated with carbamazepine administration: experience in brain-damaged children.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In one child, a second course of carbamazepine resulted in a return of the dystonia.",Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The currently available clinical and neuropharmacologic data suggest that carbamazepine may be an antagonist of dopamine and that this property is responsible for the production of dystonia.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We have cared for three children in whom four episodes of dystonia proceeding to opisthotonus occurred in association with carbamazepine use.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Aplastic anemia and agranulocytosis in patients using methazolamide for glaucoma.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Several case reports of aplastic anemia with use of acetazolamide, and two cases with use of methazolamide, have appeared in the literature.",Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This article describes two cases of aplastic anemia, at least one of which was almost certainly induced by the use of methazolamide, and one case of agranulocytosis related to the use of methazolamide.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Squamous-cell carcinoma arising in a basal-cell epithelioma treated with 5-fluorouracil.,Squamous cell carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the development of squamous-cell carcinoma within a basal-cell epithelioma that was treated with intralesional injections of 5-FU.,Squamous cell carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lower extremity arterial insufficiency after long-term methysergide maleate therapy.,Arterial insufficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient whose case is reviewed had migraine headaches and received methysergide maleate for 13 years.,Migraine
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of Erythema Multiforme Bullosum in patient of lepromatous leprosy with pulmonary tuberculosis due to Rifampicin is described.,Erythema multiforme
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Erythema multiforme bullosum due to rifampicin.,Erythema multiforme
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Renal damage associated with long term use of lithium carbonate.,Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report 2 cases of renal damage associated with lithium carbonate treatment.,Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In two patients with mycosis fungoides, a squamous cell carcinoma developed during therapy with psoralens plus long-wave ultraviolet radiation (PUVA).",Squamous cell carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hyperglycemia and diabetic coma: possible relationship to diuretic-propranolol therapy.,Diabetic coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients developed diabetic coma when taking a combination of a thiazide diuretic and propranolol.,Diabetic coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An insulin-dependent diabetic patient with nephropathy developed severe acidosis after treatment with acetazolamide for glaucoma.,Acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe acidosis from acetazolamide in a diabetic patient.,Acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This progressed to tracheal compression with stridor after he had taken some aspirin for relief of the neck pain.,Tracheal compression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Five cases of clindamycin-associated pseudomembranous colitis in leukaemic patients are reported.,Pseudomembranous colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An infertile patient with amenorrhea-galactorrhea syndrome lost vision during a pregnancy occurring after Bromocryptine treatment.,Blindness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal acute tubular necrosis occurred in 1 patient in whom intravesical formalin was used to control massive persistent hemorrhage from radiation cystitis.,Renal tubular necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal complication of intravesical formalin during control of intractable hemorrhage from radiation cystitis.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intravenous sodium bicarbonate appears to be indicated prophylactically in combating the associated metabolic acidosis due to absorbed formic acid.,Metabolic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A young woman developed galactorrhea during treatment with a new dibenzoxazepine antidepressant, amoxapine.",Galactorrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 15-kg weight gain developed in a patient during the third week of ibuprofen therapy.,Weight increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Edema associated with ibuprofen therapy.,Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It should be recognized that ibuprofen may be associated with salt and water retention in the same fashion as previously described with phenylbutazone and indomethacin.,Fluid retention
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Allopurinol-associated hand and foot deformities in chronic tophaceous gout.,Limb deformity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Telescoped digits of the hands and feet developed in a 69-year-old male with severe chronic tophaceous gout during allopurinol treatment.,Syndactyly
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient with coccidioidal meningitis was treated with intrathecally administered amphotericin B, and an acute toxic delirium with EEG abnormalities developed.",Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neurotoxicity of intrathecal administration of amphotericin B.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In keeping with findings in the literature, the aortic wall in this case was damaged by secondary changes following irradiation and Bleomycin treatment.",Aortic dissection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Cardiac glycosides are thought to prevent doxorubicin cardiomyopathy by competitively inhibiting doxorubicin at its receptor sites, but ouabain has a much shorter half life than doxorubicin and its metabolites and so is less effective than digoxin.",Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Doxorubicin cardiotoxicity: possible role of digoxin in its prevention.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Minor electrocardiographical changes were noted in five out of six patients who were not receiving a cardiac glycoside and four out of six who were receiving ouabain, and none of the 16 who were receiving digoxin.",Electrocardiogram abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One other patient on digoxin stopped taking it and developed cardiomyopathy.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One patient on ouabain also developed cardiomyopathy.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A healthy, 30-year-old man, exposed to sulindac on two separate occasions, had an incapacitating isolated idential sensory neuropathy.",Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, we describe the first reported case of isolated paresthesia and peripheral neuropathy, without systemic involvement, secondary to sulindac administration.",Paraesthesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition, loading with one low oral dose of serine produced psychotic symptoms 5 h later which lasted 3-6 h.",Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversal of ergotamine-induced arteriospasm by mechanical intra-arterial dilatation.,Arterial spasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two patients with imminent gangrene of the extremities caused by ergot-induced arteriospasm underwent mechanical dilatation of the arteries when conventional measures such as anticoagulation, vasodilation, and sympathetic blockade produced no improvement.",Arterial spasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors describe a case of combined lithium and haloperidol toxicity characterized by hyperpyrexia, severe rigidity, mutism, and development of irreversible tardive dyskinesia.",Hyperpyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors postulate that two types of combined lithium-neuroleptic toxicity occur: a neuroleptic malignant extrapyramidal syndrome and a lithium toxicity that occurs in combination with phenothiazines, primarily thioridazine.",Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chlorambucil-induced chromosome damage to human lymphocytes is dose-dependent and cumulative.,Acquired chromosomal abnormality
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylactoid reaction to 50% solution of dextrose.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Preliminary results suggest that the higher concentrations of dextrose induce increased histamine release from blood cells, and that this phenomenon is more marked in diabetic, and particularly diabetic-allergic, individuals.",Histamine release test
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients with extrinsic asthma and coexistent insulin-dependent diabetes mellitus sustained an anaphylactoid reaction after the intravenous administration of 50% solution of dextrose.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Salicylate hepato toxicity in rheumatic fever.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two children with rheumatic fever developed anicteric hepatitis while on high-dose aspirin therapy.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 36-year-old man being treated with cisplatinum, vinblastine, and bleomycin for testicular carcinoma developed a dense left homonymous hemianopsia, encephalopathy, and a partial nondominant parietal lobe syndrome.",Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Transient left homonymous hemianopsia and encephalopathy following treatment of testicular carcinoma with cisplatinum, vinblastine, and bleomycin.",Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"An association of granulocytopenia, eosinophilia, skin reaction and hepatitis during propylthiouracil (PTU) therapy for thyrotoxicosis in a 47 year old black female is reported.",Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Multiple complications of propylthiouracil treatment: granulocytopenia, eosinophilia, skin reaction and hepatitis with lymphocyte sensitization.",Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A toxic encephalopathy characterized by depressed level of consciousness, marked irritability, and ataxia developed in seven children, 5 years of age and younger, following administration of an antiemetic combination of pentobarbital and pyrilamine maleate.",Ataxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Optic neuropathy associated with penicillamine therapy in a patient with rheumatoid arthritis.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Optic neuropathy developed in a patient with rheumatoid arthritis who had been receiving D-penicillamine for about 1 year.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The case resembles two previously reported cases of optic neuropathy which occurred in patients with Wilson's disease who were receiving penicillamine.,Optic Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient developed transient, acute myopia while on isotretinoin (Accutane) therapy for acne.",Acute myopia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There was a clear relationship between restarting the Accutane and recurrence of the transient myopia.,Pseudomyopia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient acute myopia resulting from isotretinoin (accutane) therapy.,Pseudomyopia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Allergic contact dermatitis to compound tincture of benzoin.,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nineteen cases of allergic contact dermatitis to compound tincture of benzoin are described.,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Autopsy evidence of herpesvirus infection was found in visceral organs of four leukemic patients who had received large doses of cytarabine (cytosine arabinoside; Ara-C) shortly before their death.,Herpes virus infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In three of these patients the infection was clinically unsuspected; in the fourth, cutaneous herpes zoster developed after administration of 300 mg of cytarabine daily for the preceding five days.",Herpes zoster cutaneous disseminated
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Visceral herpesvirus infections in leukemic patients receiving cytarabine.,Herpes virus infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinical and morphological features of gold neuropathy.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three cases of gold-related neuropathy are reported.,Neuropathy peripheral
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe neurotoxicity with methyl G: CALGB experience.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A young patient experienced marked sinus tachycardia while smoking marijuana and receiving therapeutic doses of nortriptyline.,Sinus tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Marked sinus tachycardia resulting from the synergistic effects of marijuana and nortriptyline.,Sinus tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It is concluded that 'cerebral atrophy' on CT scans may represent an accumulative effect of ACTH and that ACTH should be given with the utmost discretion, and in as low a dose as possible.",Cerebral atrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disulfiram-like reactions with newer cephalosporins: cefmenoxime.,Alcohol intolerance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of a disulfiram-like reaction with cefmenoxime.,Alcohol intolerance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"k bipolar manic-depressive patient, developed while on lithium prophylaxis, akathisia at therapeutic serum lithium levels and subsequently bucco-linguo-masticatory dyskinesia.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute leukopenia associated with silver sulfadiazine therapy.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patients from endemic areas referred to transplant centers may be at high risk for disseminated histoplasmosis when treated with long-term prednisone for graft-versus-host disease.,Histoplasmosis disseminated
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure most likely was secondary to the nephrotoxic effect of captopril on chronically hypoperfused kidneys.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In a patient with severe renovascular hypertension, nonoliguric acute renal failure developed after she received captopril treatment.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nonoliguric acute renal failure after captopril therapy.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Captopril-induced acute reversible renal failure.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The 5 patients had severe renovascular disease which might thus represent a significant risk factor in the development of captopril-induced acute renal failure.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report 5 cases of acute reversible renal failure coinciding with the onset of treatment with captopril in patients with severe drug-resistant hypertension.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of mania associated with fluoxetine.,Mania
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A depressed woman with no history of bipolar illness developed a manic episode during treatment with fluoxetine.,Mania
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Alopecia, nausea, and vomiting were attributed to the cyclophosphamide component of the therapy.",Alopecia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Haemolytic-uraemic syndrome complicating long-term mitomycin C and 5-fluorouracil therapy for gastric carcinoma.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three cases of acute renal toxicity in patients receiving long-term therapy with mitomycin C and 5-fluorouracil are reported.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Oral 25-hydroxyvitain D3 in treatment of osteomalacia associated with ileal resection and cholestyramine therapy.,Ileectomy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe histological osteomalacia developed in a woman with Crohn's disease 2 years after ileal resection and the start of cholestyramine therapy.,Osteomalacia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Treatment of lithium tremor with metoprolol.,Tremor
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients with bipolar affective disorder and a history of bronchospastic phenomena experienced tremor during lithium carbonate therapy.,Tremor
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intravenous diazepam exacerbated the seizures.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 52-year-old Black woman on phenytoin therapy for post-traumatic epilepsy developed transient hemiparesis contralateral to the injury.,Hemiparesis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A possible mechanism for focal neurological deficit in brain-damaged patients on phenytoin therapy is discussed.,Delayed ischaemic neurological deficit
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient hemiparesis caused by phenytoin toxicity.,Hemiparesis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 7-year-old boy developed a severe unilateral grand mal seizure at the age of 5 years (phenobarbitone therapy); 1.5 years later valproate (2-propylpentanoic acid, VPA) was added to the therapy.",Generalised tonic-clonic seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cefoxitin therapy for Mycobacterium fortuitum bacteremia with associated granulomatous hepatitis.,Granulomatous liver disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Stroke-like syndrome after gold sodium thiomalate induced vasomotor reaction.,Transient ischaemic attack
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gold nephropathy due to auranofin obscured by tolmetin pseudoproteinuria.,Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 52-year-old, white female developed low-grade fever, cough, and dyspnea after 8 weeks treatment with sodium aurothiomalate for rheumatoid arthritis.",Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary gold toxicity.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cyclophosphamide can rarely cause interstitial pneumonitis and fibrosis.,Fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cyclophosphamide pneumonitis.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The temporal sequence of the respiratory insufficiency and the histopathology, when compared to the previous examples in the literature, suggest that cyclophosphamide was aetiologically responsible for the lung disease.",Lung disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A reversible toxic liver damage was observed in a non-alcoholic woman treated with disulfiram.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Toxic hepatitis induced by disulfiram in a non-alcoholic.,Hepatitis toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One type of SMON is associated with acrodermatitis enteropathica which has a very high frequency of occurrence in association with administration of clioquinol.,Acrodermatitis enteropathica
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Four patients receiving high-dose tamoxifen for greater than 1 year have demonstrated similar retinal changes.,Retinal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tamoxifen retinopathy.,Retinopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These findings suggest that the corneal and retinal changes are the result of a toxic effect of tamoxifen when used in the doses and duration described.,Retinal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mammary gigantism is a rare complication of D-penicillamine treatment.,Breast hyperplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although they had complex medical problems, the high serum concentrations of ampicillin at the time of seizures without their recurrence after discontinuing the antibiotic suggest that the seizures were related to the ampicillin therapy.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ampicillin-associated seizures.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients had ampicillin-associated seizures.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After the patient discontinued rifampicin, the skin lesions cleared completely within 5 weeks without any systemic medication.",Yaws of skin
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pemphigus foliaceus induced by rifampicin.,Pemphigus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pemphigus foliaceus was seen in a patient with pulmonary tuberculosis during rifampicin therapy.,Pemphigus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Hyponatremia in patients treated with lorcainide, a new antiarrhythmic drug.",Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In eight patients, a mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L was observed after a single 200 mg intravenous dose of lorcainide.",Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It is concluded that SIADH is an important side effect of lorcainide therapy.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One patient developed severe hyponatremia with serum Na+ of 108 mEq/L when hydrochlorothiazide was given to control hypertension.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sixteen of 33 patients developed significant hyponatremia and hypoosmolality during oral treatment with lorcainide.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acute intravascular hemolysis developed when a diabetic patient, previously treated with glyburide, was started on another oral sulfonylurea drug, chlorpropamide.",Haemolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chlorpropamide-induced hemolytic anemia.,Haemolytic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,In a 61-year-old man receiving chronic low-dosage amiodarone an interstitial pneumopathy was observed.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interstitial pneumopathy and low-dosage amiodarone.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Alternating sinus rhythm and intermittent sinoatrial block induced by propranolol.,Sinus arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Alternating sinus rhythm and intermittent sinoatrial (S-A) block was observed in a 57-year-old woman, under treatment for angina with 80 mg propranolol daily.",Sinus arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The abnormal rhythm disappeared with the withdrawal of propranolol and when the drug was restarted a 2/1 S-A block was seen.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This was accepted as evidence for propranolol being the cause of this conduction disorder.,Conduction disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A further case of anaphylactoid reaction to methylprednisolone is reported.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylactoid reaction to methylprednisolone pulsed therapy for multiple sclerosis.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although lung specimens were lacking from these three patients, it is suggested that the pulmonary toxicity of CCNU may be dose-related.",Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary fibrosis subsequent to high doses of CCNU for chronic myeloid leukemia.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The responsibility of CCNU in the pathogenesis of pulmonary fibrosis seems very likely.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two patients treated for chronic myeloid leukemia with high doses of CCNU (1100 mg/m2 and 1240 mg/m2, respectively) developed a fatal pulmonary fibrosis.",Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Additive pulmonary toxicity with melphalan and busulfan therapy.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a 59-year-old patient with chronic myeloid leukemia, who developed severe interstitial lung fibrosis after short term and sequential treatment with melphalan and busulfan.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After taking cholestyramine II sachets twice daily for two months she presented with lethargy, confusion and drowsiness.",Confusional state
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cholestyramine induced hyperchloremic metabolic acidosis.,Metabolic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It is presumed that her hyperchloremic metabolic acidosis was secondary to cholestyramine because of the similarity to pediatric reports; the rapid and lasting response to intravenous sodium bicarbonate; the absence of another etiology; normal serum potassium, chloride and bicarbonate despite continued spironolactone therapy after recovery.",Metabolic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The first reported case, in an adult, of cholestyramine induced hyperchloremic metabolic acidosis is a 70 year old female with a two year history of primary biliary cirrhosis confirmed by histologic and immunologic criteria.",Metabolic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although myelosuppression is mild, immunosuppression and superinfection are potential hazards of treatment with DCF.",Immunosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The ocular toxicity of DCF, previously described as conjunctivitis, appears to be a keratitis of moderate severity which requires further study.",Conjunctivitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because there were no other obvious causes of renal failure in either patient, we propose that skeletal muscle ischemia developed during vasopressin infusion, followed by release of myoglobin and renal damage.",Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myoglobinuria and acute renal failure associated with intravenous vasopressin infusion.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myoglobinuria and acute renal failure were observed in two patients with vasopressin-treated gastrointestinal hemorrhage.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A major limitation in the use of amphotericin B is its potential to cause nephrotoxicity.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amphotericin B nephrotoxicity in humans decreased by salt repletion.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Experience with five patients in whom impaired renal function developed early during amphotericin B therapy is reported.,Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gynecomastia developed in two epileptic patients some months after the addition of oral fluoresone 750 mg daily to the phenobarbital and phenytoin already being administered.,Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Gynecomastia in epileptics treated with phenobarbital, phenytoin and fluoresone: two case reports.",Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case report of withdrawal dyskinesia associated with amoxapine.,Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Occurrence of withdrawal dyskinesia indicates that the neuroleptic effects of amoxapine may be clinically significant.,Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors describe a case of oral-facial dyskinesia that occurred after discontinuation of amoxapine, and antidepressant which may also have neuroleptic effects.",Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of toxic hepatitis caused by combination therapy with methotrexate and etretinate in the treatment of severe psoriasis is presented in a 47-year-old woman.,Hepatitis toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Toxic hepatitis due to combination therapy with methotrexate and etretinate in psoriasis.,Hepatitis toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metabolic balance studies and rechallenge with hydrochlorothiazide were undertaken to investigate the mechanism of the thiazide-induced hyponatremia.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 58-year-old woman developed unilateral acute angle-closure glaucoma four days after the application of a patch of transdermal scopolamine delivery system (TRANSDERM-V).,Angle closure glaucoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case history of a 15-year-old boy who developed incapacitating tardive dyskinesia that resolved during treatment with deanol is presented.,Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cephalosporins are most likely associated with Vitamin K deficiency.,Vitamin K deficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Coagulopathy associated with the use of cephalosporin or moxalactam antibiotics in acute and chronic renal failure.,Coagulopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Moxalactam is more likely to be associated with platelet dysfunction.,Platelet dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Nevertheless, the coagulopathy seemed to be most closely associated with the administration of the cephalosporin.",Coagulopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nine azotemic patients who developed a coagulopathy associated with the use of either cephalosporin or moxalactam antibiotics are reported.,Coagulopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fatal pulmonary fibrosis following 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) therapy.",Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombotic thrombocytopenic purpura during penicillamine therapy in rheumatoid arthritis.,Thrombotic thrombocytopenic purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thrombotic thrombocytopenic purpura (TTP) developed in a patient with seropositive rheumatoid arthritis (RA) after 2 1/2 months of treatment with penicillamine.,Thrombotic thrombocytopenic purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, no prior cases of penicillamine-induced TTP in RA have been reported.",Thrombotic thrombocytopenic purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Amiodarone hydrochloride, a new antiarrhythmic agent, has been associated with pulmonary toxicity characterized by cough, dyspnea and diffuse pulmonary infiltrates.",Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Possible recurrence of amiodarone pulmonary toxicity following corticosteroid therapy.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this recurrence of amiodarone pulmonary toxicity has not been reported previously.",Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a case of fibrosing alveolitis, diagnosed by lung biopsy, in a patient receiving amiodarone which responded to corticosteroid therapy.",Idiopathic pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 61 year-old male patient developed gynecomastia after starting theophylline.,Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gynecomastia associated with theophylline.,Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,No other endogenous or exogenous cause for the gynecomastia could be found except for the theophylline.,Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The gynecomastia regressed when the theophylline was discontinued.,Gynaecomastia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Parenteral-verapamil-induced sustained hypotension.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The incidence of oral-verapamil-induced hypotension in the presence of concomitant beta-adrenergic blockade by the oral route is quite rare.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of sustained hypotension after administration of parenteral verapamil.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 69-year-old man developed pure red cell aplasia after taking fenoprofen for ten months.,Aplasia pure red cell
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pure red cell aplasia associated with fenoprofen.,Aplasia pure red cell
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case represents the third example of erythroid aplasia associated with an anti-inflammatory agent and the first instance due to fenoprofen.,Aplastic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Drug-induced psychosis resulted from the administration of quinacrine hydrochloride at a dosage of 100 mg twice daily for the treatment of discoid lupus.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of priapism associated with trazodone is described.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Priapism associated with trazodone therapy: case report.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Charcoal haemoperfusion and cysteamine therapy led to the rapid removal of the paracetamol from the body and consequently prevented the development of severe hepatic necrosis.,Hepatic necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Anaphylactoid shock, disseminated intravascular coagulation, and anuric renal failure requiring dialysis occurred in a patient receiving zomepirac sodium for toothache.",Anaphylactoid shock
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Focal renal cortical necrosis associated with zomepirac.,Renal cortical necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The mechanism of anaphylactoid reaction to zomepirac in this case, therefore, remains unclear.",Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cimetidine-induced fever.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cimetidine is a rare cause of drug-induced fever.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 56-year-old male parkinsonian patient developed a unique behavioral change following the oral administration of cinepazide, a cerebral vasodilator.",Neuropsychological symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Unique behavioral change with cinepazide in parkinsonism.,Neuropsychological symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 65-year-old woman, in the intensive care unit because of septic shock and acute renal failure, had a small-bowel obstruction due to Amphojel concretions.",Small intestinal obstruction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with alcoholic cerebellar degeneration had periodic alternating nystagmus during a period of phenytoin intoxication.,Nystagmus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although the data indicate an immune-complex cause for gold-salt nephropathy, the incident antigen (or antigens) and mechanism of action remain unidentified.",Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gold nephropathy.,Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Gold-salt therapy may result in damage to proximal tubules that leak renal tubular antigens, which in turn complex with autoantibody and produce an autoimmune membranous nephropathy.",Renal tubular injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The nephrotic syndrome developed in a patient receiving therapy with gold for rheumatoid arthritis.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intrahepatic cholestasis and cutaneous bullae associated with glibenclamide therapy are described in a 61-year-old diabetic patient who presented wit hypoglycaemic coma.,Dermatitis bullous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intrahepatic cholestasis and cutaneous bullae associated with glibenclamide therapy.,Dermatitis bullous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"These features have not previously been reported as side effects of glibenclamide therapy, but intrahepatic cholestasis may occur with chlorpropamide, a similar sulphonylurea agent.",Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors describe a woman with chronic schizophrenia who experienced delirium, grand mal seizure, and photosensitivity after the addition of propranolol to her neuroleptic regimen.",Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Catatonia associated with disulfiram therapy.,Catatonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neurophysiological mechanisms which aid in elucidating the role of disulfiram in the etiology of catatonia are discussed.,Catatonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first report of a catatonic syndrome occurring in a patient receiving disulfiram treatment.,Catatonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatic reactions to cyclofenil.,Liver disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thirty patients with hepatic reactions to cyclofenil, a non-steroidal drug with a stimulating effect on ovulation, are reviewed.",Liver disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since early symptoms of the toxic effects of theophylline can mimic peptic ulcer disease, cimetidine might be prescribed for the gastrointestinal symptoms with subsequent worsening of theophylline poisoning.",Peptic ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of SIADH associated with desipramine treatment in an elderly depressed woman is described.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Desipramine-associated SIADH in an elderly woman: case report.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The spectrum of renal lesions occurring during antituberculous therapy, particularly in association with rifampin, may be wider than previously suspected.",Renal lesion excision
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Within 3 weeks of beginning continuous daily isoniazid and rifampin therapy for pulmonary tuberculosis, a patient developed acute renal failure.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nephrotic range pseudoproteinuria in a tolmetin-treated patient.,Proteinuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fulminant hepatitis associated with disulfiram.,Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of fatal fulminant hepatitis caused by the use of disulfiram in a man with previously normal hepatocellular function.,Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 45-year-old woman with thyrotoxicosis developed agranulocytosis after treatment with propylthiouracil.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient was given methimazole instead of propylthiouracil but, 10 weeks later, agranulocytosis again occurred.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This is, to the best of our knowledge, the first report of a case in which agranulocytosis followed treatment with both propylthiouracil and methimazole in the same patient.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 55-yr-old man developed prolonged jaundice and sicca complex after a course of thiabendazole therapy.,Jaundice
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intrahepatic cholestasis and sicca complex after thiabendazole.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The literature on thiabendazole-induced cholestasis and its association with sicca complex is reviewed.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intracranial hemorrhage and focal seizures secondary to use of L-asparaginase during induction therapy of acute lymphocytic leukemia.,Partial seizures
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Dural sinus thrombosis developed in two children with acute lymphoblastic leukemia during induction treatment with vincristine sulfate, prednisone, and asparaginase.",Cerebral venous thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The cause is presumed to be secondary to hypercoagulability due to asparaginase-induced antithrombin III deficiency.,Antithrombin III deficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Six patients with rheumatoid arthritis developed a syndrome resembling lupus erythematosus while being treated with penicillamine.,Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Systemic lupus erythematosus during penicillamine therapy for rheumatoid arthritis.,Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, the amount of prednisone required to maintain normotension resulted in Cushingoid features and has been discontinued.",Cushing's syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinicians should be aware of fasting hypoglycemia as an unusual but potentially serious complication of disopyramide therapy.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disopyramide (Norpace)-induced hypoglycemia.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cefoxitin-associated renal failure.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The other woman had rheumatoid arthritis and developed acute tubular necrosis after treatment with gentamicin and cefoxitin.,Renal tubular necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two elderly women suffered an acute deterioration of renal function after treatment with cefoxitin sodium.,Renal tubular necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient anuria following administration of angiotensin I-converting enzyme inhibitor (SQ 14225) in a patient with renal artery stenosis of the solitary kidney successfully treated with renal autotransplantation.,Transient anuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on a patient with renal artery stenosis who had only 1 kidney and in whom acute renal impairment developed with transient anuria after the administration of captopril.,Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 44-year-old woman is described in whom amiodarone, disopyramide, and quinidine, administered alone separately, induced atypical ventricular tachycardia (AVT, torsade de pointes).",Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amiodarone was the third drug to induce AVT in this patient; she received 200 mg/day six days per week for six months.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atypical ventricular tachycardia (torsade de pointes) induced by amiodarone: arrhythmia previously induced by quinidine and disopyramide.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two years later, 24 hours following an increase in the dose of disopyramide from 300 to 600 mg/day, AVT with syncope occurred; isoproterenol abolished the arrhythmia instantly.",Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although the existence of an acute pericarditis or an acute myocarditis as possible causes of the ST elevation cannot be fully ruled out, the sudden onset, prominent magnitude, and brief duration of the ST elevation are perhaps more indicative of an acute ischemic event, possibly related to a transient coronary vasoconstriction induced by the dopamine infusion.",Arteriospasm coronary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Complete remission of the nephrosis occurred after discontinuation of hydroxychloroquine therapy.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatitis following cimetidine administration.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The case of an adult who developed both hepatic dysfunction and an impaired macrophage migration after exposure to cimetidine is discussed.,Hepatic function abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There have been only two reports of cimetidine-induced hepatitis.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 66-year-old mand suffering from severe coronary heart disease took digoxin with suicidal intent an was treated for the ensuing complete atrioventricular block with digoxin-specific antibody fragments.,Atrioventricular block complete
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Verapamil in effort-induced angina pectoris in patients with normal coronary arteries.,Angina pectoris
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Flucytosine-associated diarrhea has been previously described in 6%-10% of patients receiving the drug.,Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ulcerating enteritis associated with flucytosine therapy.,Enteritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Papilledema without peripheral neuropathy in a patient taking perhexiline maleate.,Papilloedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An adolescent male developed acute pancreatitis and pseudocyst of the pancreas 16 weeks after cessation of intramuscular L-asparaginase.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Delayed pseudocyst of the pancreas can be a complication of intramuscular L-asparaginase.,Pancreatic pseudocyst
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,L-asparaginase-induced pancreatitis has been reported during or closely following administration of the drug.,Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three cases of pseudocyst of the pancreas in two women and one man have previously been reported with the use of intravenous L-asparaginase.,Pancreatic pseudocyst
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nine delirious patients suffering from lithium intoxication were examined with the Mini-Mental State Exam (MMS) to describe the clinical course of the disorder.,Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The course of delirium due to lithium intoxication.,Delirium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Life-threatening hyperkalemia induced by arginine.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Marked hyperkalemia was observed during and immediately after an infusion of arginine monohydrochloride in two patients with severe hepatic disease and moderate renal insufficiency.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 58-year-old man with rheumatoid arthritis developed lichen planus during treatment with gold.,Lichen planus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acne provoked by gold seems not to have been described elsewhere.,Acne
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lichen planus and acne provoked by gold.,Acne
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The case history confirms that gold treatment, even in the same patient, can give rise to a wide range of skin disturbances, which in many cases do not break out until long after the drug has been withdrawn.",Skin disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Secondary hyperparathyroidism in certain patients with lithium nephrotoxicity is also possible.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These results indicate that lithium may cause biochemical hyperparathyroidism.,Hyperparathyroidism primary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 57-year-old woman with right bundle branch block +LPH and ventricular premature contractions developed complete heart block (CHB) following administration of disopyramide phosphate (Norpace).,Atrioventricular block complete
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disopyramide-induced heart block.,Atrioventricular block
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although transient increases in ectopy after bretylium therapy have been described, presumably due to catecholamine release, the occurrence of life-threatening ventricular arrhythmia leading to cardiac arrest has not previously been emphasized.",Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the first patient, two episodes of ventricular tachycardia requiring cardioversion occurred in close temporal sequence with administering bretylium.", 
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the second case, five cardiac arrests due to ventricular tachycardia and fibrillation occurred during several hours after beginning a trial of bretylium maintenance therapy for complex ventricular ectopy.",Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Paradoxical ventricular tachycardia and fibrillation after intravenous bretylium therapy.,Cardiac fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Lithium is known to cause acute renal failure and tubulo-interstitial disease, but the recently described association with proteinuria or nephrotic syndrome is little recognized.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nephrotic syndrome associated with lithium therapy.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients on long-term lithium therapy developed the nephrotic syndrome.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 67-year-old man developed diarrhea shortly after a 10-day course of oral ampicillin.,Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 73-year-old woman with non-Hodgkin's lymphoma had two episodes of severe, bilateral, sensori-neural hearing loss after vincristine therapy.",Deafness neurosensory
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bilateral acoustic (VIII) nerve palsy in this patient was most likely a manifestation of vincristine neurotoxicity.,Facial paralysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of timolol-associated heart failure in a 73-year old white man is reported.,Cardiac failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bradycardia and congestive heart failure associated with ocular timolol maleate.,Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On the second day of hospitalization, it was noted that the patient's dyspnea and sinus bradycardia could be related to a recent increase in his timolol dosage.",Dyspnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal ventricular fibrillation after treatment with digoxin in a 27-year-old man with mitral leaflet prolapse syndrome.,Ventricular fibrillation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Liver disease induced by perhexiline maleate.,Liver disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This paper reports a case of fatal perhexiline maleate liver injury.,Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute non-lymphocytic leukemia in patients with ovarian carcinoma following long-term treatment with Treosulfan (= dihydroxybusulfan).,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute non-lymphocytic leukemia occurred in eight women following long-term treatment with Treosulfan (= dihydroxybusulfan) for ovarian carcinoma.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Seven of the eight cases of acute leukemia occurred in a series of 553 patients treated with Treosulfan for ovarian cancer in the period from 1970 to 1977 and followed closely for a total of 1159 patient-years up to February 1978.,Acute leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The probability of developing acute leukemia in this study was not significantly correlated to the total cumulative dosage of Treosulfan.,Acute leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propranolol-related bronchospasm in patients without history of asthma.,Bronchospasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Regardless of a negative history of asthma, therefore, life-threatening bronchospasm must be considered a possible complication of propranolol therapy.",Bronchospasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since the bronchospasm was relieved with discontinuation of propranolol and supportive bronchodilator therapy, the bronchospasm was believed to be caused by propranolol.",Bronchospasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three patients with no history of asthma or allergy developed bronchospasm while taking propranolol for hypertension.,Bronchospasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propranolol: an unrecognized cause of central nervous system dysfunction in patients undergoing cardiopulmonary bypass.,Nervous system disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The potential role of propranolol in inducing central nervous system disturbances is emphasized, and the literature on the subject is reviewed.",Nervous system disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interstitial fibrosis of the lung is a potential complication of methotrexate therapy for psoriasis.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Progressive interstitial fibrosis with roentgenographic honeycombing developed in the case of a psoriatic patient who had been on a regimen of methotrexate for 18 years.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Progressive interstitial lung disease from prolonged methotrexate therapy.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A transient tonic pupillary response, denervation supersensitivity, and abnormal visual-evoked potentials in quinine toxicity, to our knowledge, have not been previously reported.",Visual evoked potentials abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Total blindness with a transient tonic pupillary response, denervation supersensitivity, and abnormal visual-evoked potentials developed in a 54-year-old man after the use of quinine sulfate for leg cramps.",Visual evoked potentials abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diagnosis: practolol induced sclerosing peritonitis.,Encapsulating peritoneal sclerosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case of skeletal fluorosis induced by prolonged treatment with niflumic acid, a fast-acting non-steroid antiinflammatory agent, is reported in a 35-year-old woman suffering from rheumatoid arthritis and treated, in addition, with corticosteroids.",Fluorosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After ruling out a hydrotelluric source of fluorine, the patient's fluorosis was linked to chronic use of niflumic acid, following the publication in 1978 of the 2 previously reported cases affected by this drug.",Fluorosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Niflumic acid-induced skeletal fluorosis: iatrogenic disease or therapeutic perspective for osteoporosis?,Fluorosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The fluorine contained in niflumic acid induced a marked densification of trabecular bone in all 3 cases.,Bone density increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity associated with use of D-penicillamine in rheumatoid arthritis.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"These cases and a review of the literature suggested that hepatotoxicity, though rare, should be added to the list of adverse reactions to D-penicillamine.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients with rheumatoid arthritis developed evidence of hepatotoxicity while receiving D-penicillamine.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 62-year-old Indian with diabetic nephropathy controlled with metformin, developed miliary tuberculosis for which he was treated with rifampicin, isoniazid and ethambutol.",Disseminated tuberculosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Para-aminosalicylic acid-induced hypoglycaemia in a patient with diabetic nephropathy.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The induction of hypoglycaemia with PAS in this patient suggests a potential role for PAS in the treatment of diabetes mellitus.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The introduction of para-aminosalicylic acid (PAS) led to hypoglycaemic coma.,Hypoglycaemic coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient developed papilloedema and hepatic dysfunction while being treated with perhexiline maleate.,Hepatic function abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Papilloedema and hepatic dysfunction apparently induced by perhexiline maleate (Pexid).,Hepatic function abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Markedly increased pigmementation of skin immediately overlying veins used for multiple 5-fluorouracil infusions was noted.,Skin hyperpigmentation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Unusual pigmentary changes associated with 5-fluorouracil therapy.,Skin discolouration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although useful in the management of chronic alcoholism, disulfiram is being increasingly associated with a wide spectrum of side effects and untoward medical sequelae, which now include catatonia.",Catatonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disulfiram encephalopathy as a cause of the catatonia syndrome.,Catatonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors describe a case of the catatonia syndrome associated with disulfiram therapy.,Catatonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Inappropriate antidiuretic hormone secretion after high dose vinblastine.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on a patient with an embryonal teratocarcinoma of the testicle who had the syndrome of inappropriate secretion of antidiuretic hormone after receiving a high dose of vinblastine.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Four cases of oesophageal damage associated with ingestion of the urinary anti-spasmodic agent emepronium bromide are described.,Oesophageal injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Oesophageal ulceration due to emepronium bromide.,Oesophageal ulcer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiorespiratory toxicity due to miconazole.,Cardiopulmonary failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"None of them had a history of cardiac disease, and with the possible exception of one case of cardiac arrest, where the patient received doxorubicin, no predisposing factors could be found.",Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Seven patients with hematologic malignancies who were treated with miconazole for either suspected or proven fungal infections developed eight episodes of major adverse cardiorespiratory and anaphylactic reactions.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clofibrate-induced myopathy in patients with diabetes insipidus.,Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, we have recently had four cases of clofibrate-induced myopathy in patients with diabetes insipidus due to hypothalamic lesions.",Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Physicians should therefore be aware of its occurrence and carefully monitor serum levels of CPK, GOT and GPT during the treatment of diabetes insipidus with clofibrate, especially in patients with associated hypothyroidism, latent or overt, which possibly favors the development of myopathy.",Myopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity of hycanthone in patients with metastatic breast cancer.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In a phase II study of hycanthone in patients with breast cancer we have recently observed severe hepatotoxicity, even at lower doses, which resulted in two drug-related deaths.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal interstitial pneumonitis following high-dose intermittent chlorambucil therapy for chronic lymphocyte leukemia.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Following several of these courses of therapy, respiratory distress occurred 9 to 12 days after the chlorambucil was given.",Respiratory distress
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of barbiturate-induced submassive hepatic necrosis is presented and the literature is reviewed.,Hepatic necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Barbiturate-induced submassive hepatic necrosis.,Hepatic necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient's clinical presentation, histologic features on liver biopsy and favorable course after stopping the drug suggest that barbiturates can be added to the list of agents which can cause submassive hepatic necrosis.",Hepatic necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 71-year-old man with paroxysmal atrial fibrillation who had a previous anterior myocardial infarction exhibited granulocytopenia 8 days following the administration of oral sustained-release procainamide (750 mg/day).,Granulocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sustained-release procainamide-induced reversible granulocytopenia after myocardial infarction.,Granulocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The frequency and relationship of granulocytopenia caused by sustained-release procainamide in patients with tachyarrhythmias are briefly discussed, and prior reported cases are reviewed.",Granulocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Monoclonal gammopathy and subsequent multiple myeloma in a patient on chronic diphenylhydantoin therapy.,Monoclonal gammopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The development of an IgG lambda-type monoclonal gammopathy and subsequent multiple myeloma in an epilepsy patient on diphenylhydantoin (DILANTIN) therapy for 20 years is reported.,Monoclonal gammopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We recommended periodic examination of the serum proteins in patients receiving diphenylhydantoin in order to detect development of monoclonal gammopathy.,Monoclonal gammopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Atovaquone should be added to the list of agents causing vortex keratopathy involving the corneal epithelium.,Cornea verticillata
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: We studied a case of vortex keratopathy that was associated with the use of atovaquone.,Cornea verticillata
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: Similar to previous findings of drug-induced vortex keratopathy, atovaquone vortex keratopathy is presumably caused by its lipophilic properties.",Cornea verticillata
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Vortex keratopathy associated with atovaquone.,Cornea verticillata
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Used injudiciously, naloxone can lead to withdrawal syndrome, return of severe pain, and other adverse effects.",Pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, there remain questions concerning whether these drugs, especially methimazole (MMI), may be associated with aplasia cutis congenita (ACC) and how best to avoid impairment of fetal thyroid function during their use.",Aplasia cutis congenita
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 73 year-old patient with Wolff-Parkinson-White syndrome and paroxysmic supraventricular tachycardia developed an acute reversible encephalopathy within 15 days of initiation of flecainide.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 64 year old man with recurrent metastatic squamous cell carcinoma of the head and neck developed severe skin rash and bone marrow aplasia 4 and 7 days, respectively, following a single dose of 40 mg/m2 methotrexate (MTX).",Bone marrow failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bone marrow aplasia and severe skin rash after a single low dose of methotrexate.,Bone marrow failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of an extensive skin rash following a single dose of MTX may be an early warning sign for life-threatening bone marrow aplasia.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the absence of mucositis or diarrhea, severe dermatologic toxicity following a single low dose of the drug suggests an 'allergic' or acute hypersensitivity reaction to MTX in this patient.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chlormadinone acetate withdrawal syndrome under combined androgen blockade for advanced prostate cancer.,Withdrawal syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The second had acute cystitis and was treated by sulphonamide and the third developed myopia coincident with metronidazole treatment for trichomonas vaginalis.,Myopia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nephrotic syndrome related to systemic lupus erythematosus after griseofulvin therapy.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, this is the first case of griseofulvin-exacerbated lupus in which nephrotic syndrome has been observed.",Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 16-year-old male who developed nephrotic syndrome related to membranous glomerulopathy with clinical and serological evidence of systemic lupus erythematosus after treatment with griseofulvin.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The first patient developed mild nitritoid symptoms and pain in a band-like distribution, corresponding to T10-T12 dermatomes, shortly after gold sodium thiomalate (GSTM) injection.",Nitritoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The second patient experienced mild nitritoid symptoms following several GSTM injections prior experiencing a cerebrovascular accident within several hours of her next injection.,Nitritoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute sensorineural hearing loss following intravenous ketoralac administration.,Deafness neurosensory
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Both PAN and methotrexate have been independently demonstrated to cause sensorineural hearing loss.,Deafness neurosensory
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We recommend the cautious use of ketorolac in patients with underlying illnesses where NSAID-induced ototoxicity could result in adverse otologic consequences.,Ototoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a 20-year-old female with polyarteritis nodosa (PAN) who developed bilateral sensorineural hearing loss 25 minutes after receiving 30 mg of intravenous ketoralac.,Deafness neurosensory
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylactoid reactions with intraperitoneal cisplatin.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARIES: While conducting a protocol evaluating the efficacy of intraperitoneal cisplatin and hyperthermia in the treatment of recurrent ovarian cancer, 3 patients were noted to exhibit anaphylactoid reactions.",Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: We conclude that a high dose combined with a short infusion time increases the risk of anaphylactoid reactions with the administration of intraperitoneal cisplatin.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: Anaphylactoid reactions have been described previously with cisplatin administration.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"During her third cycle, she again received cisplatin 100 mg/m2 over 30 minutes and developed palmar pruritus, urticaria, and edema.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the occurrence of anaphylactoid reactions to intraperitoneal cisplatin in 3 patients.,Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We observed 5 reactions in 3 patients that appear to be related to a high dose-infusion time ratio, indicating that dose and rate of infusion may be important factors in precipitating anaphylactoid reactions with cisplatin.",Anaphylactoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Etoposide-related myocardial infarction.,Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The occurrence of a myocardial infarction is reported after chemotherapy containing etoposide, in a man with no risk factors for coronary heart disease.",Myocardial infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 9-year-old boy developed acute renal failure following intravenous acyclovir (30 mg/kg per day) administered for 6 days to treat herpetic encephalitis.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure in a child associated with acyclovir.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anterior ischemic optic neuropathy secondary to interferon alfa.,Optic ischaemic neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Anterior ischemic optic neuropathy may complicate treatment with interferon alfa.,Optic ischaemic neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the occurrence of anterior ischemic optic neuropathy as a complication of treatment with interferon alfa and to consider the possible underlying mechanisms for this association.,Optic ischaemic neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"PATIENTS: Two patients, ages 40 and 51 years, undergoing treatment with interferon alfa for malignant neoplasms experienced sudden bilateral, sequential visual loss with disc-related field defects and segmental optic disc edema.",Blindness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The interval between initiating treatment with interferon alfa and onset of anterior ischemic optic neuropathy was similar to that of interferon-associated vascular retinopathy.,Optic ischaemic neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors describe a case of neuroleptic malignant syndrome that occurred in a patient on amitriptyline and lithium carbonate.,Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE SUMMARIES: Two patients with stable hypothyroidism experienced symptoms of hypothyroidism with increased serum thyroid-stimulating hormone (TSH) concentrations after switching from 1 levothyroxine product to another.,Blood thyroid stimulating hormone increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Evidence is shown in this report that adenosine was associated with dangerous worsening of arrhythmia in patients with atrial flutter.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Life-threatening alterations in heart rate after the use of adenosine in atrial flutter.,Heart rate abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Comparable adverse effects, such as disorientation and temporary amnesia, have been reported in patients in the analogous agent, propranolol.",Disorientation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe a probable case of transient global amnesia caused by propafenone.,Transient global amnesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Probable propafenone-induced transient global amnesia.,Transient global amnesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of acute subdural haematoma originating spontaneously from an angiomatous meningioma in a patient receiving prophylactic aspirin therapy is presented.,Subdural haematoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intracranial haemorrhage from a meningioma in a patient receiving aspirin prophylaxis: a case report.,Haemorrhage intracranial
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Beneficial effect of low-dose mianserin on fluvoxamine-induced akathisia in an obsessive-compulsive patient.,Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Extrapyramidal side effects induced by some selective serotonin reuptake inhibitors (SSRIs), i.e. fluoxetine and sertraline, have been previously reported in patients with depression and obsessive-compulsive disorder (OCD).",Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, the occurrence and management of akathisia induced by fluvoxamine have not been described.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the presented case fluvoxamine-induced akathisia in an OCD patient was partially resistant to the anticholinergic agent biperiden, and was successfully treated with the 5-HT2A/5-HT2C antagonist mianserin.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 42 year old man, treated for testicular carcinoma with combination chemotherapy that included bleomycin, developed life threatening interstitial pneumonitis.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe bleomycin lung toxicity: reversal with high dose corticosteroids.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report suggests that bleomycin lung toxicity may be reversible if treated aggressively.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversal of gold-induced neutropenia with granulocyte colony-stimulating factor (G-CSF).,Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We have successfully overcome severe neutropenia in an RA patient treated with gold salts, using granulocyte colony-stimulating factor (G-CSF), reducing the duration of neutropenia and risk of infection.",Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Arrhythmias and cardiac arrest have been reported during amphotericin B administration but no effective technique has been described to prevent them.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Correction of serum electrolyte imbalance prevents cardiac arrhythmia during amphotericin B administration.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,I saw two patients with kala-azar resistant to sodium stibogluconate who developed cardiac arrest after amphotericin infusion (in spite of tolerating a test dose).,Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe two cases that illustrate the use of lithium in the treatment of veterans with PTSD who complained of serious problems with irritability or angry outbursts.,Aggression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Graves' hyperthyroidism following transient thyrotoxicosis during interferon therapy for chronic hepatitis type C.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case showed sequential manifestation from transient thyrotoxicosis to the appearance of TSH-receptor autoantibodies, and then the occurrence of Graves' hyperthyroidism during IFN therapy.",Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of Graves' hyperthyroidism induced by long-term interferon (IFN) therapy.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acute INH neurotoxicity was not suspected on the first admission; however, when readmitted 4 weeks later with another seizure, the diagnosis of acute INH neurotoxicity was made.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute isoniazid neurotoxicity in an urban hospital.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: We have seen an increased incidence of acute INH neurotoxicity because of the resurgence of TB in New York City.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In patients with a known access to INH, seizures should be considered to be caused by INH toxicity unless proved otherwise.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVES: To describe the presentation and treatment of acute isoniazid (INH) neurotoxicity appearing at an inner-city municipal hospital.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Parenteral pyridoxine, the specific antidote for INH-induced refractory seizures, should be readily available in every emergency department in the areas similarly experiencing increasing trends of TB.",Epilepsy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: At our institution, no children appeared with acute INH neurotoxicity in the period 1985 through 1990, whereas seven patients were treated from 1991 through 1993.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Arterial hypertension associated with topical ocular use of phenylephrine in dogs.,Hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Squamous metaplasia in these cases appears to be a consequence of progestin therapy.,Metaplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the finding of squamous metaplasia within endometrial glands occurring as a result of progestin therapy of hyperplasia.,Metaplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Extensive squamous metaplasia was found in endometrial glands following progestin therapy.,Metaplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fever caused by the use of furosemide was proved; the fever resolved after discontinuation of this medication and recurred after its reintroduction.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Furosemide-associated fever.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The dose-limiting toxicity of KW-2149 is pulmonary toxicity.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Musculoskeletal complaints were the presenting symptoms in four of 44 children (9%) treated for relapsed Wilms' tumors with ifosfamide, a derivative of cyclophosphamide.",Musculoskeletal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Recognition of a potential drug-induced Fanconi syndrome is important when managing pediatric oncology patients previously treated with ifosfamide.,Fanconi syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Our cases constitute the most severe cases of benzarone hepatotoxicity reported so far, and comprise the first cases of (sub)fulminant hepatitis and cirrhosis related to benzarone.",Hepatic cirrhosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe hepatotoxicity related to benzarone: a report of three cases with two fatalities.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report three cases of severe hepatotoxicity related to benzarone, a benzofuran derivative.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We stress the potential of benzarone to cause hepatotoxicity, which usually resembles severe chronic active hepatitis.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case study: a modified topical treatment regimen for sodium warfarin-induced necrotizing fasciitis.,Necrotising fasciitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case study describes an atypical case of refractory, sodium warfarin-induced necrotizing fasciitis and myonecrosis.",Muscle necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Clinicians who manage cachectic patients, particularly those with protracted diarrhoea and/or receiving anti-malarial drugs including mefloquine, should be aware of the risk of severe hypoglycaemia.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mechanisms and triggering factors of hypoglycaemia induced by mefloquine and some other anti-malarial quinine analogues are discussed.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mefloquine-associated hypoglycaemia in a cachectic AIDS patient.,Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Quinine and its isomer quinidine are well-known causes of iatrogenic hypoglycaemia, due to excessive insulin secretion.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of hypoglycaemia after mefloquine therapy (1,500 mg over two days) for severe gastrointestinal cryptosporidiasis in a cachectic AIDS patient with protracted diarrhoea.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because sumatriptan can cause coronary artery vasospasm, patients with significant risk factors for coronary artery disease should be carefully evaluated for cardiovascular disease prior to the use of sumatriptan.",Arteriospasm coronary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiac arrest following use of sumatriptan.,Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,I report a 35-year-old woman with occult coronary artery disease who experienced cardiac arrest within minutes after receiving a first-time dose of subcutaneous sumatriptan for migraine.,Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sotalol-induced bradycardia reversed by glucagon.,Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of sotalol-induced bradycardia reversed by glucagon.,Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Secretory endometrial adenocarcinoma in a patient on tamoxifen for breast cancer: a report of a case.,Endometrial stromal sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This unusual pattern of low-grade endometrial carcinoma adds to the spectrum of uterine neoplasia associated with tamoxifen therapy.,Endometrial stromal sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We believe that this is the first report of secretory carcinoma of the endometrium associated with tamoxifen use.,Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Well-differentiated endometrial adenocarcinoma of the secretory type (FIGO Grade 1) with minimal myometrial invasion occurred in a postmenopausal patient on tamoxifen therapy 5 years after mastectomy for breast carcinoma.,Endometrial stromal sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Esophageal candidiasis following omeprazole therapy: a report of two cases.,Oesophageal candidiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Esophageal candidiasis was diagnosed at endoscopy in two patients receiving omeprazole therapy.,Oesophageal candidiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,High-grade atrioventricular block during dipyridamole stress testing.,Atrioventricular block second degree
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case in which dipyridamole induced high-grade atrioventricular (AV) block that responded promptly to intravenous aminophylline but not to atropine.,Atrioventricular block second degree
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Aggressive management of doxorubicin-induced cardiomyopathy associated with 'low' doses of doxorubicin.,Cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There is a dose-effect relationship between doxorubicin and the incidence of symptomatic cardiac failure.,Cardiac failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ovarian endometrioid carcinoma and endometriosis developing in a postmenopausal breast cancer patient during tamoxifen therapy: a case report and review of the literature.,Endometriosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The association with prolonged unopposed estrogen-like stimulation with tamoxifen as a possible factor in the development of ovarian endometrioid carcinoma is discussed.,Ovarian endometrioid carcinoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present the first case of ovarian endometrioid carcinoma and endometriosis in a postmenopausal patient who was treated with tamoxifen for breast cancer.,Endometriosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Multifocal inflammatory leukoencephalopathy associated with levamisole therapy.,Leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Observations in our patient suggest that the leukoencephalopathy that developed in previously reported patients who received 5-fluorouracil and levamisole may have been caused at least partly by levamisole.,Leukoencephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of noncardiogenic pulmonary edema by ethanolamine oleate.,Non-cardiogenic pulmonary oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, EO-induced noncardiogenic pulmonary edema has not been reported in human.",Non-cardiogenic pulmonary oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of noncardiogenic pulmonary edema developed after therapeutic trial of EO as sclerosing agent for esophageal varix.,Non-cardiogenic pulmonary oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Five patients are described in whom only gentamicin sulfate appeared responsible for acute renal failure.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Gentamicin-associated acute renal failure.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Renal failure appeared 8 to 17 days after beginning gentamicin therapy and was characterized by creatinine clearances 4 to 10 ml/min, urine to plasma creatinine ratios less than 20, urinary sodium concentrations 16 to 60 mEq/liter, proteinuria, and cylindruria.",Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 15-year follow-up of phenytoin-induced unilateral gingival hyperplasia: a case report.,Gingival hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,INTRODUCTION-The aim of this case report is to present a 15-year follow-up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH).,Gingival hypertrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of generalized cutaneous sclerosis associated with muscle and oesophageal involvement in a patient exposed to herbicides containing bromocil, diuron and aminotriazole.",Scleroderma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Albuterol-induced hypokalemia and its potential cardiac toxicity are discussed briefly.,Cardiotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypokalemia after normal doses of neubulized albuterol (salbutamol).,Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The cases of two asthmatic patients who became hypokalemic after inhalation of normal doses of albuterol are presented.,Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propoxyphene-induced wide complex dysrhythmia responsive to sodium bicarbonate therapy has not been previously reported in the literature.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case report: mannitol nephrotoxicity syndrome: role of hemodialysis and postulate of mechanisms.,Nephropathy toxic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hemodialysis should be performed for rapid reversal of mannitol-induced ARF.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,High-dose intravenous mannitol infusion in various clinical settings may result in acute renal failure (ARF).,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mannitol-induced ARF responds promptly to hemodialysis with rapid resolution of anuria and recovery of renal failure.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The literature is also reviewed for ARF associated with mannitol infusion in patients who received dialysis and those who did not receive dialysis; and the possible mechanism(s) of mannitol nephrotoxicity are discussed.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is a report of a case of anuric ARF after high-dose mannitol infusion for treatment of narrow-angle glaucoma that readily responded to acute hemodialysis.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients with extrapyramidal side effects after the use of fluphenazine decanoate were evaluated by means of IBZM-SPECT.,Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Flumazenil reversal of benzodiazepine-induced sedation for a patient with severe pre-ECT anxiety.,Sedation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARY: A 68-year-old woman developed a dry, irritating cough within one month of starting quinapril therapy for the treatment of essential hypertension.",Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cough induced by quinapril with resolution after changing to fosinopril.,Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"OBJECTIVE: To report a case of chronic, nonproductive cough secondary to the angiotensin-converting enzyme (ACE) inhibitor quinapril, with complete resolution after switching to another ACE inhibitor, fosinopril.",Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The cough continued for the duration of therapy with quinapril.,Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of cough following the administration of quinapril, with complete resolution after changing to the alternative ACE inhibitor fosinopril in a patient with essential hypertension.",Cough
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fracture of the femoral neck occurred in one patient during PSL therapy, although the relationship between the fracture and PSL therapy was uncertain.",Femoral neck fracture
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cefuroxime-induced acute renal failure.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In our patient, DIAN possibly was related to cefuroxime, but the patient did not experience associated allergic symptoms.",Drug hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The diagnosis was supported by the temporal course of renal deterioration during exposure to cefuroxime and improvement on its discontinuation; the pattern repeated with rechallenge.,Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This is the first reported case of suspected DIAN due to cefuroxime.,Drug hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of basilar invagination which is thought to have arisen from the patient's intrauterine exposure to phenytoin is presented.,Platybasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Basilar invagination and mid-line skeletal abnormalities due to in utero exposure to phenytoin.,Platybasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This patient developed sequential symptoms including alternative hemiparesis, dysarthria and altered consciousness 5 days after the second course of HD-MTX (8 gm/m2 by 6 h continuous infusion) with leucovorin rescue.",Altered state of consciousness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transient neurological disturbances induced by the chemotherapy of high-dose methotrexate for osteogenic sarcoma.,Transient ischaemic attack
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a 5-year-old boy with CF who had a stricture of the hepatic flexure region with associated narrowing due to submucosal fibrosis of the transverse colon, secondary to high-lipase pancreatin therapy.",Large intestinal stenosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute pancreatitis associated with danazol treatment for endometriosis.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Additionally, danazol produces hepatocellular damage in approximately 10% of women.",Hepatocellular injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypo-oestrogenic and anabolic/androgenic side-effects of danazol are well known by the gynaecologist and some of them are present in > 50% of patients being treated for endometriosis.,Hypo-oestrogenic and anaOestrogen deficiencybolic/androgenic side-effects
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The present report describes the first case of acute pancreatitis associated with danazol treatment of endometriosis.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acyclovir neurotoxicity: clinical experience and review of the literature.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acyclovir produces neurologic symptoms that resemble extension of viral infection into the central nervous system.,Neurological symptom
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Systemic disease, most commonly renal dysfunction, preceded all 30 reported cases of acyclovir neurotoxicity.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We discuss our observations in the cases of two patients with acyclovir neurotoxicity and review the findings of all previous reports in the English language literature.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Response of a promethazine-induced coma to flumazenil.,Coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the first case of a patient in a promethazine-induced coma responding to treatment with flumazenil.,Coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amebic abscess of the spleen complicated by metronidazole-induced neurotoxicity: case report.,Hepatic amoebiasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a patient with a liver abscess due to Entamoeba histolytica, in whom metronidazole therapy (total dose, 21 g over 14 days) was complicated by reversible deafness, tinnitus, and ataxia and who relapsed 5 months later with a splenic abscess.",Ataxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Actinomycin D associated hepatic veno-occlusive disease--a report of 2 cases.,Venoocclusive liver disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There are now reports of liver failure following treatment of childhood cancers with AMD.,Hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Phenylpropanolamine-induced psychosis.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a cae of paranoid psychosis following use of a decongestant containing PPA and summarize the case report literature of psychiatric adverse effects to PPA in which doses were known and stated to be within recommended guidelines.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Although budesonide may be beneficial because of its anti-inflammatory effects, clinicians should be alert to its potential for causing contact dermatitis.",Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Contact dermatitis due to budesonide: report of five cases and review of the Japanese literature.,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"METHODS: Five cases of contact dermatitis due to budesonide, a nonhalogenated steroid, are described.",Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,RESULTS: Budesonide use can cause contact dermatitis.,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although other nitrites induce methemoglobinemia, exposure to methyl nitrite during phenylpropanolamine production appears to be a new cause of occupational methemoglobinemia.",Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methemoglobinemia: an occupational hazard of phenylpropanolamine production.,Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,During and after IFN therapy we should consider the possibility of occurrence of IDDM as well as other autoimmune diseases and observe the clinical course carefully.,Type 1 diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Four years after the beginning of IFN therapy, he acutely developed moderate hyperglycemia and severe ketonuria with positive islet cell antibody, and then 28 units/day of insulin injection was started.",Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Occurrence of IDDM during interferon therapy for chronic viral hepatitis.,Type 1 diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of IDDM which occurred during interferon therapy for chronic hepatitis.,Type 1 diabetes mellitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Four patients who manifested symptoms of the antiepileptic drug (AED) hypersensitivity syndrome during therapy with carbamazepine are reported.,Drug reaction with eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Recurrent hypotension immediately after seizures in nortriptyline overdose.,Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The use of methotrexate (MTX) has been contraindicated for treatment of severe psoriasis in HIV infection on the basis of six previously reported cases in which MTX appeared to potentiate opportunistic infections and accelerate HIV disease.,HIV infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: This case describes the clinically significant increase of INR in an elderly patient after adding a chemotherapy regimen of levamisole and 5-FU to a previous regimen of warfarin alone.,Prothrombin time prolonged
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, prolongation of 5-FU half-life and an increase in INR have been reported with the concurrent use of 5-FU and warfarin.",Prothrombin time prolonged
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cholestatic liver disease with ductopenia (vanishing bile duct syndrome) after administration of clindamycin and trimethoprim-sulfamethoxazole.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"One patient who received clindamycin had liver biopsy findings of marked cholestasis, portal inflammation, bile duct injury and bile duct paucity (ductopenia).",Gallbladder injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The second patient, who developed cholestasis after receiving trimethoprim-sulfamethoxazole, had marked duct paucity in the liver biopsy.",Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This is the first description, to our knowledge, of ductopenia apparently caused by clindamycin.",Vanishing bile duct syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Three years later, treatment with ampicillin caused another episode of cholestatic hepatitis with cholestasis and duct paucity on rebiopsy.",Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"METHODS: A patient who developed dramatic, permanent vision loss after a 9-month course of treatment with ethambutol and isoniazid for pulmonary tuberculosis is presented.",Blindness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"RESULTS: Ethambutol, and to a lesser extent isoniazid, are both implicated in the development of visually related side effects.",Visual impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,There is documentation of ocular toxicity with ethambutol when administered at dosages generally pronounced as being safe.,Ocular toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Toxic optic neuropathy associated with ethambutol: implications for current therapy.,Toxic optic neuropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Currently the use of zidovudine is one of the few specific measures available, and as a potentially teratogenic and fetotoxic agent, any decision for its use requires evaluation of the potential for fetal damage.",Foetal damage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In a series of 104 cases of intentional or inadvertent use of zidovudine at differing gestations in pregnancy, there were eight spontaneous first trimester abortions, eight therapeutic terminations, and eight cases of fetal abnormality occurring among a total of 88 cases where the pregnancy progressed.",Congenital anomaly
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Zidovudine use in pregnancy: a report on 104 cases and the occurrence of birth defects.,Congenital anomaly
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Celiprolol pneumonitis.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Inadvertent subsequent rechallenge with celiprolol led to recurrence of the pneumonitis, 10 weeks after drug readministration.",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report on a patient who developed hypersensitivity pneumonitis during treatment with the beta-blocker, celiprolol.",Hypersensitivity pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ibopamine-induced reversible leukopenia during treatment for congestive heart failure.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible leukopenia was documented in an 81-year-old woman treated with adjunctive ibopamine 100 mg t.i.d. for chronic congestive heart failure.,Leukopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Diphenylhydantoin apparently adversely affected both the clinical and biochemical parameters of the acute intermittent porphyria.,Porphyria acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Significant clinical improvement of the porphyria followed withdrawal of the diphenylhydantoin.,Porphyria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 53-year-old male, without any prior history of psychosis, developed schizophrenia 4 days after starting low-dose bromocriptine therapy for a macroprolactinoma.",Schizophrenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Bromocriptine-induced schizophrenia.,Schizophrenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Concurrent acute megaloblastic anaemia and pneumonitis: a severe side-effect of low-dose methotrexate therapy during rheumatoid arthritis.,Anaemia megaloblastic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In a patient suffering from rheumatoid arthritis, we report the first simultaneous occurrence of two side effects of low-dose methotrexate: an acute megaloblastic anaemia and a pneumonitis.",Anaemia megaloblastic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"An 11-year-old boy who was treated with a relatively high dose of methotrimeprazine meleate (Levemepromazine) a phenothiazine antipsychotic drug, was admitted to the pediatric intensive care unit suffering from respiratory distress syndrome.",Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The association of phenothiazine overdose and respiratory distress syndrome merits consideration.,Acute respiratory distress syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In two patients, apomorphine remained effective in the morning, but increased the intensity of the dyskinesias in the afternoon.",Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report on three observations of parkinsonian patients with levo-dopa-induced diphasic dyskinesias, who received subcutaneous apomorphine to reduce the duration of abnormal movements.",Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fulminant hepatitis with severe lactate acidosis in HIV-infected patients on didanosine therapy.,Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This prompted us to suspect that ddI might be responsible for fulminant hepatitis in all three AIDS patients.,Hepatitis fulminant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two cases of fulminant hepatic failure in HIV-1-infected patients treated with didanosine (ddI).,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Generalized argyria after habitual use of AgNO3.,Argyria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A case of fluoxetine induced seizures, in a person with Down syndrome, is described.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Seizures associated with fluoxetine therapy are uncommon.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Seizures associated with fluoxetine therapy.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although fluoxetine-induced headache occurred in one patient, the other five reported no side effects at the doses used.",Headache
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Sodium valproate and carbamazepine, antiepileptic drugs that are associated with a relatively low rate of adverse cutaneous reactions, should be added to the growing list of drugs that produce psoriasiform eruptions.",Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present findings from three patients who experienced a psoriasiform eruption apparently due to the antiepileptic agents sodium valproate and carbamazepine.,Psoriasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe diffuse interstitial pneumonitis induced by carmustine (BCNU).,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a fatal case of acute interstitial pneumonitis in a patient treated with carmustine (BCNU) for a brain tumor.,Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 78-year-old man with a transvenous cardioverter defibrillator system developed frequent shocks during oral procainamide therapy.,Phantom shocks
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Electrical proarrhythmia with procainamide: a new ICD-drug interaction.,Proarrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Based on our experience and on previously published data, serum ammonia levels appear to be indicated in all ED patients on valproic acid therapy who present with altered mental status.","Hallucination, visual"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hyperammonemia has been described as a complication of valproic acid therapy but may often be overlooked as a cause of lethargy in the postictal patient who presents to the emergency department.,Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hyperammonemia secondary to valproic acid as a cause of lethargy in a postictal patient.,Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We present the case of a postictal patient with lethargy, hyperammonemia, otherwise normal liver function tests, and a therapeutic valproic acid level.",Hyperammonaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Central nervous system toxicity associated with meperidine use in hepatic disease.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"She received an accidental 450-mg bolus injection of morphine intrathecally and developed hypertension, status epilepticus, intracerebral hemorrhage, and respiratory failure.",Hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mitomycin C (MMC) is an alkylating agent that has been recently associated with the hemolytic-uremic syndrome (HUS).,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pulmonary hemorrhage as a clinical manifestation of hemolytic-uremic syndrome associated with mitomycin C therapy.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pulmonary hemorrhage is an uncommon feature in the HUS, and seems to appear especially in the HUS associated with MMC therapy.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe two women who developed HUS after MMC therapy and presented massive pulmonary bleeding.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clonidine-induced bradycardia in patients with spinal cord injury.,Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Possible mechanisms by which clonidine decreases spasticity are described, probable mechanisms of induced bradycardia are reviewed, and specific treatment recommendations for the use of clonidine in spinal cord injured patients are presented.",Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Though hypotension, dry mouth, and constipation are well-documented possible adverse effects, the possibility of clonidine-induced bradycardia is less well recognized and is rare.",Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A high dose of cotrimoxazole induced hyperkalaemia with the elevation of serum creatinine and blood urea, and increased urinary N-acetyl glucosaminase after several days of the drug administration in these patients; one patient became unconscious.",Renal impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Hyperkalaemia with renal tubular dysfunction by oral therapy of sulfamethoxazole-trimethoprim (co-trimoxazole) is described in 2 elderly Japanese patients with lymphoid malignancy, who developed Pneumocystis carinii pneumonia and improved.",Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hyperkalaemia with renal tubular dysfunction by sulfamethoxazole-trimethoprim for Pneumocystis carinii pneumonia in patients with lymphoid malignancy.,Hyperkalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Five cases (four from the literature and one new case) are presented in which patients unsuspected of having vitamin B12 deficiency developed subacute combined degeneration of the spinal cord following nitrous oxide anesthesia.,Subacute combined cord degeneration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Neurologic degeneration associated with nitrous oxide anesthesia in patients with vitamin B12 deficiency.,Congenital neurological degeneration
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patients with vitamin B12 deficiency are exceedingly sensitive to neurologic deterioration following nitrous oxide anesthesia.,Neurological decompensation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: Fluoxetine, a highly specific serotonin reuptake inhibitor, has been reported to cause sexual dysfunction in a minority of patients.",Sexual dysfunction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Captopril-induced bone marrow suppression in two cardiac patients with trisomy 21.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Neutropenia is an infrequent complication following administration of the angiotensin-converting enzyme (ACE) inhibitor, captopril.",Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two cases of neutropenia following captopril use in cardiac patients with trisomy 21.,Neutropenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Can magnesium sulfate therapy impact lactogenesis?,Lactation disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"No explanation for this delay was found, other than the possibility that magnesium sulfate treatment impeded lactogenesis.",Delayed onset of lactation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Four days after the initial injection of 3.6 mg of goserelin acetate, severe dyspnea developed due to worsening pleuritis carcinomatosa, which was considered as a flare-up.",Autoimmune disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cerebrovascular complications of L-asparaginase therapy in children with leukemia: aphasia and other neuropsychological deficits.,Aphasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Children with acute lymphoblastic leukemia (ALL), treated with L-asparaginase are at risk for cerebral thrombosis or hemorrhage because of coagulation protein deficiencies.",Cerebral thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myoclonus and seizures disappeared after discontinuation of L-dopa and the introduction of valproate sodium (VPA).,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Myoclonus and seizures in a patient with parkinsonism: induction by levodopa and its confirmation on SEPs.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Myoclonus was induced and enhanced by L-dopa, developing into generalized seizures.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We described the occurrence of L-dopa-induced myoclonus and seizures in a case of parkinsonism with its SEPs findings.,Myoclonus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Unintended exposure to acyclovir early in pregnancy, which is not uncommon, may cause excessive maternal and physician anxiety.",Anxiety
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A severe form of exophthalmos resulting from lithium therapy has not been described in the literature.,Exophthalmos
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lithium therapy was discontinued because of poor compliance to the medication and intolerable polyuria.,Polyuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Regression of thyrotoxic ophthalmopathy following lithium withdrawal.,Endocrine ophthalmopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The case of a bipolar patient who developed thyrotoxicosis with severe exophthalmos while on lithium therapy is described.,Exophthalmos
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The exophthalmos improved dramatically within 72 hours of the withdrawal of lithium.,Exophthalmos
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe abdominal pain in low dosage clofazimine.,Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a 41 yr old leprosy patient treated for 10 yrs with clofazimine who underwent laparotomy for severe abdominal pain.,Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amphotericin B overdose in pediatric patients with associated cardiac arrest.,Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Amphotericin B overdose can be fatal in children and infants.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hydrocortisone may decrease the incidence of mortality associated with cardiac arrhythmias in children receiving amphotericin B overdoses.,Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,INTERVENTIONS AND RESULTS: Cardiac complications were observed in five pediatric patients who received between 4.6 and 40.8 mg/kg/d of amphotericin B.,Cardiac disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report the first five cases of amphotericin B overdose with secondary cardiac complications in a pediatric population.,Cardiac disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypertension develops in most patients after transplantation when immunosuppression is based on cyclosporine and prednisone.,Hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Sudden death in an infant from methemoglobinemia after administration of ""sweet spirits of nitre"".",Sudden death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The administration of ""sweet spirits of nitre"" (4% ethyl nitrite CH3CH2ONO in 70% ethyl alcohol) was followed by acute methemoglobinemia and severe anoxic metabolic acidosis in infant twins, Methylene blue administration reversed methemoglobinemia in both, but one twin died from the consequences of hypoxemia.",Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxic effects in a child receiving valproate and carnitine.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,L-Carnitine supplementation has been recommended to prevent the fatal hepatotoxic effects associated with valproic acid.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report on a child with fatal valproate-related hepatotoxic effects despite this supplementation.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case is reported of a 40 year old woman treated with intraventricular IL-2 for leptomeningeal disease who developed progressive cognitive dysfunction.,Cognitive disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Delayed neurotoxicity of intraventricular interleukin-2: a case report.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The potential for progressive brain injury and subsequent disability related to intraventricular IL-2 therapy is discussed.,Brain injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Albeit rare among Western patients, such lithium-associated thyroid dysfunctions appeared to be more likely to occur in Hong Kong Chinese.",Thyroid disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Four Chinese female patients who suffered from manic-depressive disorder and underlying autoimmune thyroiditis developed transient episodes of thyrotoxicosis during maintenance lithium therapy.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lithium-associated transient thyrotoxicosis in 4 Chinese women with autoimmune thyroiditis.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"They seemed to involve multiple aetiological factors, such as autoimmune thyroid disease, the toxic and immunomodulatory roles of lithium and perhaps genetic and dietary factors.",Transfusion-related immunomodulation reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although retinoic acid is well tolerated by the majority of patients with this disease, a potentially fatal complication of this kind of treatment has been reported: ""the retinoic acid syndrome"".",Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: It is probable that foscarnet contributed to the electrolyte disorders and symptomatology in this patient.,Electrolyte imbalance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: Electrolyte disorders associated with foscarnet are reviewed.,Electrolyte imbalance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Foscarnet-induced severe hypomagnesemia and other electrolyte disorders.,Electrolyte imbalance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of possible foscarnet-induced severe hypomagnesemia and other electrolyte disorders.,Electrolyte imbalance
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient experienced muscle twitches, tremulousness, and anxiety on day 17 of foscarnet therapy.",Anxiety
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Interference with the cortisol axis by the microtubule antagonist, CPH82.",Adrenal insufficiency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The results clearly demonstrate that CPH82 was associated with suppression of the endogeneous production of ACTH and cortisol with a concomitant paradoxical picture of clinical hypercortisolism.,Hyperadrenocorticism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A variety of movement disorders are known to occur in association with carbamazepine (CBZ) therapy in adults and children, but development of tics has been described infrequently and only in patients with underlying Tourette's syndrome or other movement disorders.",Movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Carbamazepine-induced tics.,Tic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the third child, the tics ceased after CBZ discontinuation.",Tic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These cases demonstrate that CBZ can induce simple motor tics in children.,Tic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report 3 children with epilepsy who developed facial motor tics after initiation of CBZ for complex partial seizures.,Tic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acyclovir-induced neurotoxicity: concentration-side effect relationship in acyclovir overdose.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The observation that neurotoxicity developed with a delay of 24 to 48 hours after acyclovir peak serum concentrations could explain the wide range of acyclovir levels reported in similar cases.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: Repeated blood samples were drawn in a patient with severe acyclovir overdose who developed coma and nonoliguric renal failure.,Coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To investigate the concentration-side effect relationship in a patient with severe acyclovir-induced neurotoxicity and to summarize the information available in the literature about central nervous system side effects due to acyclovir.,Nervous system disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 16-year-old white male with acute biphenotypic leukemia developed evidence of the eosinophilia myalgia syndrome associated with total parenteral nutritional support with solutions containing tryptophan, which were given during his initial induction chemotherapy and also after autologous marrow transplantation.",Eosinophilia myalgia syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan.,Eosinophilia myalgia syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thus, the eosinophilia myalgia syndrome can be associated with parenteral tryptophan administration.",Eosinophilia myalgia syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with acute esophageal variceal bleeding developed fatal rhabdomyolysis during treatment with a continuous intravenous infusion of vasopressin.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rhabdomyolysis associated with the use of intravenous vasopressin.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These multiple overlapping factors probably lead to rhabdomyolysis in a minority of patients receiving vasopressin infusion.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nonspecific but significant abnormalities have been described in the infants of women treated with disulfiram in the first trimester of their pregnancies.,Investigation abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although the essential cause of PV is unclear, its onset has occasionally been associated with drug therapy, in particular penicillamine.",Pemphigus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pemphigus vulgaris precipitated by glibenclamide therapy.,Pemphigus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient described in this paper was a 78-year-old diabetic man who developed oral lesions of PV following institution of glibenclamide therapy.,Pemphigus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Piritrexim-induced pulmonary toxicity.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The pulmonary toxicity is probably induced by piritrexim.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a patient with transitional cell carcinoma of the renal pelvis who developed respiratory dysfunction and an abnormal chest x-ray with diffuse interstitial opacities while on chemotherapy with piritrexim, a methotrexate analog.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 12 year old patient with atrial flutter is presented, in whom intravenous adenosine was followed by acceleration of the heart rate to a potentially dangerous arrhythmia.",Tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lymphoma developing in a patient with rheumatoid arthritis taking methotrexate.,Lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoproliferative diseases, but coincidence cannot be excluded.",Lymphoproliferative disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period.",Non-Hodgkin's lymphoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatotoxicity of paracetamol enhanced by ingestion of alcohol: report of two cases.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The biochemistry of paracetamol hepatotoxicity is outlined and the increased susceptibility of alcoholic patients to the hepatotoxic effects of paracetamol is remarked upon.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two fatal cases of poisoning by paracetamol are described.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of drug-induced Kaposi's sarcoma (KS) on the sole of the right foot in a 71-year-old man, treated for 6 months with corticosteroid therapy (prednisolone 25 mg/day) for pericardial effusion.",Kaposi's sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute dystonic reaction with low-dose pimozide.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This paper reports on a 6.9-year-old autistic male who developed repeated episodes of acute dystonic reactions associated with pimozide administration at the doses of 0.096 mg/kg/day and 0.032 mg/kg/day and 32 hours following pimozide withdrawal, as well as during subsequent thioridazine administration.",Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although there is one case report of cholesterol crystal embolization following t-PA therapy with only extrarenal manifestations (N Engl J Med 321:1270, 1989), this is the first reported case of atheroembolic acute renal failure following t-PA therapy.",Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cholesterol crystal embolization-associated renal failure after therapy with recombinant tissue-type plasminogen activator.,Embolism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the occurrence of renal failure due to cholesterol crystal embolization following thrombolytic therapy with intravenous recombinant tissue-type plasminogen activator (t-PA).,Embolism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Intravenous haloperidol is generally well tolerated, but multiform ventricular tachycardia has been reported.",Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anterior spinal artery syndrome--a complication of cervical intrathecal phenol injection.,Anterior spinal artery syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We have seen a case of terminal malignant melanoma in which clinical manifestations, indicative of anterior spinal artery syndrome, developed following the injection of 0.3 ml of 10% phenol-glycerine into the cervical subarachnoid space at the C4--C5 level for the control of severe right arm pain.",Anterior spinal artery syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"One patient required nursing home placement and a feeding gastrostomy as a result of the worsening parkinsonism during risperidone treatment, but was able to return home and have the gastrostomy removed after switching from risperidone to clozapine.",Gastrostomy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two of the five patients who worsened motorically also developed encephalopathy during risperidone treatment; the encephalopathy resolved when the patients were switched to clozapine treatment.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Azathioprine can cause severe myelosuppression.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Azathioprine-induced myelosuppression due to thiopurine methyltransferase deficiency in a patient with autoimmune hepatitis.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The azathioprine dose was low (1 mg/kg) and pancytopenia occurred after 56 days therapy.,Pancytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thiopurine methyltransferase deficiency occurs at a frequency of one in 300 and is associated with profound myelosuppression after a short course of azathioprine.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the first documented case of azathioprine-induced severe myelosuppression due to thiopurine methyltransferase deficiency in autoimmune liver disease.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nabumetone-associated interstitial nephritis.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"She had been taking nabumetone for 6 months, but had discontinued the agent 2 weeks before admission due to progressive edema.",Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute myeloid leukemia evolving from essential thrombocythemia in two patients treated with hydroxyurea.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this report, two cases of ET which evolved into AL without prior exposure to radiation or alkylating agents, and which were treated with long-term hydroxyurea therapy, are described.",Acute leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prolonged used of hydroxyurea in patients with ET may lead to therapy-associated acute leukemia.,Acute leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, in 1993, a clinical study involving 400 patients on the Thai-Burmese border revealed cardiac effects of antimalarial treatment with halofantrine, including one sudden death after the treatment.",Cardiac disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In the present paper, we discuss the first Japanese vivax malaria patient whose QT interval was prolonged after treatment with halofantrine.",Electrocardiogram QT prolonged
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prolongation of the QT interval observed in a Japanese patient with vivax malaria following treatment with halofantrine.,Electrocardiogram QT prolonged
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The pharmaceutical company producing Halfan has reported 8 cardiac arrests, leading to 6 deaths, when a higher dose than recommended was used, there was recent or concomitant treatment with mefloquine, there was pre-existing prolongation of the QT interval or the patient had a thiamine deficiency.",Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Supravenous hyperpigmentation in association with CHOP chemotherapy of a CD30 (Ki-1)-positive anaplastic large-cell lymphoma.,Serpentine supravenous hyperpigmentation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report an unusual pattern of supravenous hyperpigmentation occurring after CHOP chemotherapy.,Serpentine supravenous hyperpigmentation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nephrogenic diabetes insipidus and renal tubular acidosis secondary to foscarnet therapy.,Nephrogenic diabetes insipidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"No cases of renal acidosis, and only one case of nephrogenic diabetes insipidus, has been previously reported as a complication of foscarnet treatment.",Nephrogenic diabetes insipidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Our patient developed both nephrogenic diabetes insipidus and renal tubular acidosis with a temporal pattern that demonstrated a link between foscarnet therapy and these abnormalities.,Nephrogenic diabetes insipidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a patient with human immunodeficiency virus infection under treatment with foscarnet for CMV retinitis who complained of thirst and polyuria.,Polyuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Choroidal hemorrhage associated with systemic tissue plasminogen activator.,Choroidal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: The administration of tissue plasminogen activator was responsible for the large extent of hemorrhage and should be considered in the differential diagnosis of hemorrhagic choroidal detachment.,Haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To determine the cause of spontaneous choroidal hemorrhage in a 67-year-old man after a myocardial infarction and administration of tissue plasminogen activator.,Choroidal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Accelerated nodulosis during methotrexate therapy for juvenile rheumatoid arthritis.,Rheumatoid nodule
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe two patients with rheumatoid factor-positive, polyarticular-onset juvenile rheumatoid arthritis in whom accelerated nodulosis developed during methotrexate therapy.",Rheumatoid nodule
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A macrophage activation syndrome, possibly related to methotrexate toxicity, developed in a boy with systemic juvenile rheumatoid arthritis.",Haemophagocytic lymphohistiocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Jaundice induced by streptokinase.,Jaundice
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Only a few reports of overt jaundice are associated with streptokinase.,Jaundice
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although both patients recovered from the colitis after the administration of vancomycin, the first case demonstrated a relapse of the colitis after receiving a subsequent course of the same chemotherapy with cisplatin.",Colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Based on our findings, it is thus concluded that cisplatin may cause C. difficile colitis.",Clostridium difficile colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Both patients were then treated with a carboplatin alternative to cisplatin in the following courses, which resulted in neither a relapse of the colitis nor a recurrence of the malignancies up to this time.",Colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clostridium difficile colitis associated with cisplatin-based chemotherapy in ovarian cancer patients.,Clostridium difficile colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe C. difficile colitis occurred in 2 patients (6.1%) after receiving cisplatin-based combination chemotherapy for ovarian malignancies.,Clostridium difficile colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The purpose of this study was to examine the incidence and cause of Clostridium difficile colitis occurring after cisplatin-based combination chemotherapy in ovarian cancer patients.,Clostridium difficile colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with severe cholestatic jaundice induced by captopril is presented.,Jaundice cholestatic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Patients treated with captopril who develop ""atypical cholangitis"" should be suspected of having captopril-associated liver damage.",Cholangitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of nephrotic syndrome in a patient with acute myeloblastic leukemia after treatment with macrophage-colony-stimulating factor.,Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"It should be emphasized that the recurrence of nephrotic syndrome was observed after the following chemotherapy, including M-CSF, whereas the bone marrow still remained completely remitted.",Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The possibility can be raised that M-CSF accelerated the underlying renal disease in this case through enhancing macrophage accumulation into the glomerulus, leading to the development of nephrotic syndrome.",Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These evolutional changes in both proteinuria and glomerular histology suggest a close linkage between the M-CSF treatment and macrophage-related glomerular injury.,Glomerulonephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a patient with acute myeloblastic leukemia (AML) who developed nephrotic syndrome after receiving several courses of chemotherapy, including macrophage-colony-stimulating factor (M-CSF).",Nephrotic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On the fifth day of tocolysis with magnesium sulfate, nifedipine, terbutaline and betamethasone, edema developed in both labia.",Oedema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Milk-alkali syndrome induced by 1,25(OH)2D in a patient with hypoparathyroidism.",Milk-alkali syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This article presents a patient with hypoparathyroidism who was treated with calcium carbonate and calcitriol resulting in two admissions to the hospital for milk-alkali syndrome.,Milk-alkali syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After receiving 3 doses of ifosfamide/mesna, she was found to be unresponsive.",Unresponsive to stimuli
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: There was a temporal relationship between the onset of nonconvulsive status epilepticus and initiation of ifosfamide infusion.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: Central nervous system (CNS) toxicity has been described with ifosfamide, with most cases reported in the pediatric population.",Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ifosfamide-induced nonconvulsive status epilepticus.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe a patient with ifosfamide-induced nonconvulsive status epilepticus.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This represents the first report of nonconvulsive status epilepticus induced by ifosfamide.,Status epilepticus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Albendazole-induced pseudomembranous colitis.,Pseudomembranous colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although a few case reports link metronidazole with the development of pseudomembranous colitis, albendazole has not been associated with the development of this condition.",Pseudomembranous colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"While undergoing treatment with albendazole, he developed worsening diarrhea with abdominal pain and fever.",Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Oculomotor disturbances associated with 5-fluorouracil chemotherapy.,IIIrd nerve disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The ocular motor disturbances are probably an expression of regional 5-FU neurotoxicity primarily affecting the brain stem.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two patients treated with 5-fluorouracil (5-FU) for disseminated adenocarcinoma of the colon developed cerebellar dysfunction typical of 5-FU neurotoxicity.,Cerebellar syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Assessment of cortisol response was by insulin-induced hypoglycaemia in three cases, by short tetracosactrin test in two, and by low-dose tetracosactrin and 24-hour urinary cortisol/creatinine ratio in one.",Hypoglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,FINDINGS: Six children with growth retardation noted after treatment with high-dose fluticasone propionate were found to have adrenal suppression.,Adrenal suppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Growth and adrenal suppression in asthmatic children treated with high-dose fluticasone propionate.,Adrenal suppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"INTERPRETATION: When high doses of fluticasone propionate are used, growth may be retarded and adrenal suppression may occur.",Adrenal suppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: Growth retardation was observed in six severely asthmatic children after introduction of high-dose fluticasone propionate treatment (dry powder).,Growth retardation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metipranolol associated granulomatous anterior uveitis: not so uncommon as thought.,Iridocyclitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two case reports of bilateral granulomatous anterior uveitis are described in patients with open angle glaucoma treated with metripranolol 0.6% eye drops.,Uveitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A review of the literature found 11 children and 2 adults in whom intranasal desmopressin was associated with hyponatremia, all of whom experienced seizures or altered mental status.","Hallucination, visual"
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Intranasal desmopressin-induced hyponatremia.,Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When vague symptoms develop during desmopressin therapy, hyponatremia must be considered as part of the differential diagnosis.",Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Within 24 hours of fluid restriction and cessation of desmopressin, her symptoms and hyponatremia resolved.",Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Without other causes for the hyponatremia, she was diagnosed with the syndrome of inappropriate antidiuretic hormone, presumably caused by desmopressin.",Hyponatraemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Uveitis during treatment of disseminated Mycobacterium avium-intracellulare complex infection with the combination of rifabutin, clarithromycin and ethambutol.",Uveitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Does acyclovir increase serum lithium levels?,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Six days after starting acyclovir she exhibited signs of lithium toxicity.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case suggests that acyclovir when given intravenously in doses of 10 mg/kg may result in increased serum lithium concentrations.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Until additional data are available, if intravenous acyclovir is administered concurrently with lithium, we recommend closely monitoring patients for signs of lithium toxicity and measuring serum lithium levels every second or third day.",Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When measured, the serum lithium level had increased 4-fold during acyclovir therapy.",Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dapsone syndrome in cutaneous lupus erythematosus.,Drug reaction with eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe 2 patients with cutaneous lupus erythematosus who developed severe dapsone reaction after low dose therapy, with a fatal outcome in one.",Drug reaction with eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case is presented which illustrates a probably fatal interaction between minoxidil and a coagulation disorder.,Drug interaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nephrogenic diabetes insipidus (NDI) is a well-documented complication of lithium use.,Nephrogenic diabetes insipidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Potential mechanisms regarding the pathophysiology of lithium-associated CDI are discussed.,Crohn's diseaseI
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The association of central diabetes insipidus (CDI) with lithium use is rare.,Crohn's diseaseI
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"This case emphasizes the importance of the evaluation of lithium-associated polyuria with a direct measurement of plasma vasopressin, interpreted with simultaneous plasma and urine osmolality to secure the correct diagnosis and ensure appropriate therapeutic management.",Polyuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To the best of our knowledge, this is the first case of lithium-associated CDI and NDI presenting concurrently.",Crohn's diseaseI
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a patient receiving chronic lithium therapy who presented with a transient CDI occurring in the setting of underlying chronic NDI.,Crohn's diseaseI
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE: We report a case of a woman with severe human insulin-induced lipoatrophy who has been treated exclusively with recombinant DNA human insulin since the onset of IDDM.,Lipoatrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Jet-injection devices might constitute a helpful method to treat those patients affected by severe human insulin-induced lipoatrophy.,Lipoatrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Human insulin-induced lipoatrophy.,Lipoatrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To evaluate the efficacy of the administration of insulin by a jet-injector device in stopping and reversing severe human insulin-induced lipoatrophy.,Lipoatrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Improved awareness of and further investigation into the neurotoxic effects of ofloxacin may enhance its safe use.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Seizures associated with ofloxacin therapy.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The renal insufficiency of three patients and the timing of the seizures implicate accumulation of ofloxacin as a contributing factor.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe four patients who had seizures while receiving ofloxacin; no other causes were evident.,Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient is described with the characteristic features of phenytoin hypersensitivity syndrome (PHS) including fever, erythroderma, tibial and facial oedema, pinhead-sized facial pustules and abnormal liver function tests.",Liver function test abnormal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Systemic corticosteroids in the phenytoin hypersensitivity syndrome.,Drug reaction with eosinophilia and systemic symptoms
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient is described who developed a poorly differentiated sarcoma after cyclophosphamide was used to treat his rheumatoid arthritis.,Sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sarcoma complicating therapy with cyclophosphamide.,Sarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A chronic reaction associated with long-term treatment with nitrofurantoin has also been reported and causes irreversible pulmonary fibrosis.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute pulmonary reactions to nitrofurantoin are an uncommon side effect of therapy and can cause minor or life-threatening pulmonary dysfunction.,Pulmonary fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Despite the known pulmonary side effects of nitrofurantoin, there is no report of this toxicity occurring in pregnant patients.",Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nitrofurantoin-induced pulmonary toxicity during pregnancy: a report of a case and review of the literature.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of respiratory failure occurring in a woman at 16 weeks' gestation who was being treated with nitrofurantoin for a urinary tract infection.,Respiratory failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints.",Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Methemoglobinemia is another common finding among patients receiving dapsone therapy, but rarely does it result in prominent symptoms other than transient pallor.",Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acetazolamide-accelerated anticonvulsant osteomalacia.,Osteomalacia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acetazolamide may have accelerated the development of osteomalacia by several mechanisms, including increased renal calcium excretion.",Osteomalacia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Severe osteomalacia was present in two epileptic patients who were under long-term treatment with congeners of phenytoin, phenobarbital, and acetazolamide.",Osteomalacia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The delayed encephalopathy developed 9 and 22 months respectively after the first dose of intrathecal methotrexate.,Encephalopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case histories of identical twin brothers who developed concordant acute lymphoblastic leukemia at the age of 4 years and who later developed leukoencephalopathy and hydrocephalus related to central nervous system prophylaxis by, in the first case intrathecally administered methotrexate and, in the second by intrathecally administered methotrexate and cranial irradiation.",Hydrocephalus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,a 67-year-old man with bipolar disorder developed a Creutzfeldt-Jakob like syndrome during lithium carbonate treatment.,Creutzfeldt-Jakob disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lithium-induced Creutzfeldt-Jakob syndrome.,Creutzfeldt-Jakob disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Lithium neurotoxicity should be considered in Creutzfeldt-Jakob disease differential diagnosis, serial electroencephalograms being the most valuable.",Creutzfeldt-Jakob disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Several cases of lithium-induced Creutzfeldt-Jakob syndrome have been reported to date; all of them were elderly patients and a half had ""therapeutic"" lithium serum levels.",Creutzfeldt-Jakob disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A noninvasive method in the differential diagnosis of vecuronium-induced and magnesium-induced protracted neuromuscular block in a severely preeclamptic patient.,Neuromuscular blockade
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The occurrence of neuromuscular blockade and the resulting potentiation of muscle relaxants during magnesium sulfate (MgSO4) administration is well known.,Neuromuscular blockade
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We also describe a new, noninvasive method to assess magnesium-induced neuromuscular block when curariform muscle relaxant was given simultaneously.",Neuromuscular blockade
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hepatobiliary disorders associated with orally administered terbinafine have rarely been reported.,Hepatobiliary disorder prophylaxis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Terbinafine-induced cholestatic liver disease.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a case of prolonged terbinafine-induced cholestatic liver disease.,Cholestasis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A patient with a large hydatid cyst of the left lobe of the liver developed metabolic acidosis following rather liberal use of cetrimide-chlorhexidine solution as a scolicidal agent.,Metabolic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Metabolic acidosis induced by cetrimide-chlorhexidine solution in hydatid cyst surgery.,Metabolic acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An unusual case of Ecstasy poisoning.,Poisoning
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a case of poisoning with 3,4-methylenedioxymet-amphetamine Ecstasy that presented with all the features suggestive of a fatal outcome, including a creatinine phosphokinase level markedly higher than any previously reported.",Poisoning
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, dermatologists should be cautious about a photosensitivity reaction induced by mequitazine or other phenothiazine-derivative drugs.",Photosensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In addition, an immediate erythematous macule was observed on the photopatch test site of mequitazine directly after UV exposure which was similar to the immediate erythema noted in chlorpromazine photoallergy.",Erythema
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In case no. 2, the pathogenic mechanism seemed to be persistent light reaction preceded by systemic photoallergy, as he had taken mequitazine for 6 months, and there were strong positive photopatch test results with immediate erythema reaction, cross-reaction to promethazine, decreased MED to both UVA and UVB, and persistence of the photosensitivity over a 3-year follow-up period after discontinuation of the mequitazine.",Drug hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Mequitazine seemed to play a part similar to chlorpromazine, and absence of mequitazine-induced photosensitivity may be due to a relatively low dosage of the drug.",Photosensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Two cases of mequitazine-induced photosensitivity reactions.,Photosensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We experienced 2 cases of mequitazine-induced photosensitivity reaction in patients who took mequitazine for their dermatologic problems.,Photosensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Keratitis in methamphetamine abusers.,Keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Methamphetamine's extensive physiologic effects, inconsistent street purity, and multiple routes of administration offer many possibilities for injury to the cornea.",Injury corneal
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Potential causes of methamphetamine-related keratitis can be divided into four categories resulting from (a) direct pharmacologic and physical effects of methamphetamine; (b) the toxic effects of diluting or ""cutting"" agents such as lidocaine and quinine; (c) effects related to the route of drug administration (intravenous, inhalation, smoking); and (d) manufacture-related effects of exposure to unintentional caustic contaminants in the final product.",Keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The increasing prevalence of methamphetamine abuse and the severity of the associated ulcers should alert ophthalmologists to the problem of methamphetamine-related keratitis.,Keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report four cases of severe corneal ulceration in methamphetamine abusers.,Ulcerative keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"BACKGROUND: Methotrexate (MTX) may induce liver damage, which in some psoriatics will lead to fibrosis or cirrhosis.",Hepatic cirrhosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: This study confirmed that in most patients MTX-induced liver cirrhosis is not aggressive.,Hepatic cirrhosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, continued low-dose MTX led, in spite of normal liver tests, 8 years after the last biopsy to liver failure and death in 1 of our patients.",Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate-induced liver cirrhosis.,Hepatic cirrhosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Studies performed 10 years ago on 25 patients with MTX-induced liver cirrhosis indicated that this type of cirrhosis was not of an aggressive nature.,Hepatic cirrhosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After therapy for diabetic coma with insulin (containing the preservative cresol) and electrolyte solutions was started, the patient complained of increasing myalgia, developed a high fever and respiratory and metabolic acidosis and lost consciousness.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, other factors or drugs (e.g. cresol) are thought to induce MH.",Hyperthermia malignant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This case supports the assessment that MH and diabetes are associated diseases and that cresol could possibly trigger MH.,Hyperthermia malignant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The use of beclomethasone diproprionate inhaler complicated by the development of an eosinophilic pneumonia reaction.,Eosinophilic pneumonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal intravascular autoimmune hemolytic anemia after fludarabine treatment for chronic lymphocytic leukemia.,Autoimmune haemolytic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Physicians should be aware of the risk of severe AIHA in CLL patients with a history of AIHA or positivation of the DAT during previous fludarabine administration, or in case of secondary fixation of complement to the red cell membrane occurring during fludarabine treatment.",Autoimmune haemolytic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The occurrence of severe AIHA in CLL patients treated with fludarabine has been reported by several authors.,Autoimmune haemolytic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of a patient with chronic lymphocytic leukemia (CLL) who developed fatal intravascular autoimmune hemolytic anemia (AIHA) after fludarabine treatment.,Autoimmune haemolytic anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"When the patient was treated again with fludarabine nine months later, the DAT became positive with anti-IgG and anti-C3d antiglobulins after the second course of treatment.",Coombs direct test positive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,She had just finished a 3-week course of intravenous tobramycin for bronchiectasis and had an elevated serum tobramycin trough level 1 week before the onset of tetany.,Tetany
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tetany in a child with AIDS receiving intravenous tobramycin.,Tetany
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This pattern is suggestive of renal toxicity due to tobramycin.,Nephropathy toxic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Insulin-induced lipoatrophy in type I diabetes.,Lipoatrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To test the hypothesis that tumor necrosis factor (TNF)-alpha may mediate the loss and the dedifferentiation of subcutaneous fat tissue in the insulin-induced lipoatrophies of a diabetic patient who presented extensive lesions.,Lipoatrophy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate is an effective but potentially toxic treatment for psoriasis.,Exposure to toxic agent
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Painful erosion of psoriatic plaques is a less common sign of methotrexate toxicity that may precede evidence of bone marrow suppression.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Well-known signs of methotrexate toxicity include bone marrow suppression and oral and gastrointestinal ulceration.,Myelosuppression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After treatment with cimetidine, there was a rapid deterioration with decreased oxygen saturation and arterial PO2 values.",Hypoxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Caution with use of cimetidine in tolazoline induced upper gastrointestinal bleeding.,Upper gastrointestinal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, given the clinically significant result to the interaction between tolazoline and cimetidine we report, the use of cimetidine in tolazoline induced upper gastrointestinal hemorrhage should deserve more attention.",Upper gastrointestinal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Hypoxemia improved during continuous tolazoline infusion, but gastrointestinal bleeding occurred.",Gastrointestinal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Zolpidem (Ambien), a relatively new nonbenzodiazepine sedative-hypnotic, was involved in the death of a 39-year-old obese male who was being treated for depression and insomnia.",Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Zolpidem tissue concentrations in a multiple drug related death involving Ambien.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Infants are particularly susceptible to chronic nitrate-induced methemoglobinemia because of their low stomach acid production, large numbers of nitrite-reducing bacteria, and the relatively easy oxidation of fetal hemoglobin.",Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After induction of general anesthesia and administration of a standard dose of intravenous esmolol hydrochloride, her cardiac rhythm progressed to asystole.",Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiac arrest after esmolol administration: a review of acute beta-blocker toxicity.,Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Atenolol induced memory impairment: a case report.,Memory impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,His impaired memory was found to be due to the atenolol he was on and he made a complete recovery on withdrawing the beta-blocker.,Memory impairment
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A potential role for renal and hepatic impairment in the observed protracted course of amiodarone-induced thyrotoxicosis is suggested.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Failure of plasmapheresis, corticosteroids and thionamides to ameliorate a case of protracted amiodarone-induced thyroiditis.",Thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of amiodarone-induced thyrotoxicosis of protracted duration, unresponsive to conventional thionamide therapy, with therapy limited by severe adverse drug reactions.",Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Psychotic disorder associated with isoniazid.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We evaluated a patient who developed a psychotic disorder after 4 months of isoniazid prophylaxis for a positive tuberculosis tine test.,Psychotic disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case report is presented concerning the administration of ketanserin in the treatment of pulmonary vasoconstriction and right ventricular failure following the infusion of protamine in a patient undergoing coronary artery bypass surgery and mitral valve replacement.,Vasoconstriction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ketanserin in the treatment of protamine-induced pulmonary hypertension.,Pulmonary hypertension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The reversal of heparin by protamine may cause severe hemodynamic deterioration, characterized by systemic hypotension, pulmonary hypertension, and bronchoconstriction.",Bronchospasm
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A drug addict with staphylococcal endocarditis treated with methicillin, who developed massive proteinuria and acute nephritic syndrome is described.",Nephritic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Focal glomerulonephritis and interstitial nephritis in methicillin-treated, heroin-related infective endocarditis.",Glomerulonephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS/RESULTS: This paper presents a new case of rifabutin uveitis and a review of the various published reports to date.,Uveitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,over the past 3 years there have been several reports of uveitis associated with rifabutin therapy.,Uveitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Uveitis associated with rifabutin therapy: a clinical alert.,Uveitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE DESCRIPTION: A 59-year-old man with known neurocysticercosis developed a large cerebral infarction during praziquantel therapy.,Cerebral infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Large cerebral infarction during praziquantel therapy in neurocysticercosis.,Cerebral infarction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DATA SYNTHESIS: Genetic deficiencies in DPD, the rate-limiting enzyme responsible for 5-FU catabolism, may occur in 3% or more of patients with cancer putting them at increased risk for unusually severe adverse reactions (e.g., diarrhea, stomatitis, mucositis, myelosuppression, neurotoxicity) to standard doses of 5-FU.",Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dihydropyrimidine dehydrogenase deficiency: a pharmacogenetic defect causing severe adverse reactions to 5-fluorouracil-based chemotherapy.,Adverse reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"PURPOSE/OBJECTIVES: To describe the pharmacogenetic syndrome of dihydropyrimidine dehydrogenase (DPD) deficiency, which predisposes patients with cancer to potentially lethal adverse reactions following 5-fluorouracil (5-FU)-based chemotherapy.",Adverse reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The principle treatment for DPD-deficient patients with severe acute 5-FU reactions is supportive care; however, the administration of thymidine potentially may reverse severe 5-FU-induced neurologic symptoms such as encephalopathy and coma.",Coma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 49-year-old man with Crohn's disease treated with prednisone and mesalamine (5-ASA) developed worsening respiratory distress and fever.,Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mesalamine-induced hypersensitivity pneumonitis.,Hypersensitivity pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mesalamine may cause hypersensitivity pneumonitis in patients with Crohn's disease.,Hypersensitivity pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Immunosuppression elicited by the extensive administration of prednisolone was suspected for the initiation of the generalized mite infestation.,Infestation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,BACKGROUND: Colchicine has a known adverse effect on wound healing through its inhibitory effect on tubulin-dependent cell functions and through collagenase activation.,Impaired healing
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: The findings in these two patients suggest that colchicine may delay corneal wound healing.,Impaired healing
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Delay of corneal wound healing in patients treated with colchicine.,Impaired healing
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report on two patients with corneal ulcers refractory to conventional treatment while the patients were undergoing oral colchicine therapy.,Ulcerative keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors suggest that in patients with corneal ulcers refractory to conventional treatment who are receiving colchicine, cessation of colchicine therapy should be considered.",Ulcerative keratitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fulminant hepatic failure associated with bicalutamide.,Acute hepatic failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 17-year-old female patient who had been taking oral minocycline (50 mg twice daily) for 3 weeks for acne developed an eruption that progressed to an exfoliative dermatitis.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fever, lymphadenopathy, eosinophilia, lymphocytosis, hepatitis, and dermatitis: a severe adverse reaction to minocycline.",Dermatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Delayed hypersensitivity to flurbiprofen.,Type IV hypersensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Eye movement disorders in bone marrow transplant patients on cyclosporin and ganciclovir.,Binocular eye movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We postulate that cyclosporin, possibly together with ganciclovir, can produce transient brain stem or neuromuscular dysfunction with eye movement abnormality in occasional patients.",Binocular eye movement disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSION: While thrombosis has been reported with GnRH-a therapy in men with prostate cancer, its association with treatment in this benign case may have been a consequence of the massive tumor size.",Thrombosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The possible effects of tamoxifen upon the uterus are discussed in this article, in view of reports of tamoxifen associated with endometrial carcinoma and endometriosis.",Endometrial cancer
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Case study: adverse response to clonidine.,Adverse reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Four cases of adverse experiences with clonidine are described.,Adverse reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,In one instance a systemic hypoglycemic reaction resulting in head trauma and confusion ended in an emegency hospital admission following the substitution of acetohexamide for acetazolamide.,Confusional state
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Discontinuation of the itraconazole caused resolution of the drug eruption.,Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Primary cutaneous coccidioidomycosis and subsequent drug eruption to itraconazole in a dog.,Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Its overall toxicity is considerably less compared to standard induction chemotherapy; however, it is associated with a high incidence of a potentially fatal symptom complex referred to as ""retinoic acid syndrome."" This report describes a patient with APL who developed the syndrome a few weeks after initiating induction therapy with ATRA despite being treated for hyperleukocytosis.",Adverse event
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Eleven days after initiation of therapy with amiodarone, the patient experienced syncope and was noted to have recurrent episodes of polymorphous ventricular tachycardia.",Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nonsustained polymorphous ventricular tachycardia during amiodarone therapy for atrial fibrillation complicating cardiomyopathy.,Ventricular tachycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The probable proarrhythmic action of amiodarone, although rare, is reviewed along with a discussion of the novel use of intravenous magnesium sulfate therapy.",Arrhythmia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute asthma associated with sustained-release verapamil.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although dyspnea associated with verapamil administration has been reported, this is the first report of an elderly asymptomatic asthmatic patient with hypertension who developed an acute asthma attack following sustained-release verapamil administration.",Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Sustained-release verapamil is thought to be the cause of the asthma attack in this patient because she was not taking any other preparations; the symptoms started with the administration of sustained-release verapamil and were relieved after its discontinuation.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe a patient with asymptomatic bronchial asthma and hypertension who developed an acute asthma attack after receiving sustained-release verapamil.,Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"She continued taking verapamil for 6 months, then, on her own, stopped all medications including the sustained-release verapamil, and her asthma symptoms disappeared.",Asthma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cephalexin rash in infectious mononucleosis.,Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The ampicillin rash occurring in cases of infectious mononucleosis is well documented.,Drug eruption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The case of a patient with infectious mononucleosis treated with cephalexin who later showed a rash is presented and the previous literature is reviewed.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The rash seen in this patient, who was treated with cephalexin, may be similar to the rash seen with ampicillin treatment of patients with infectious mononucleosis.",Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A possible case of carbamazepine induced pancreatitis.,Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors report a case of acute pancreatitis (AP) occurring in a patient under treatment with carbamazepine (CBZ) for post-traumatic petit mal epilepsy, and review the current literature of drug-induced AP.",Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The evidence of high plasmatic levels of CBZ and the absence of other aetiologic factors lead the authors to conclude that the overdose of CBZ could have represented the precipitating of the episode of acute pancreatitis.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although risk factors for MTX-induced pulmonary toxicity are poorly understood, the presence in 3 out of 5 of our patients of pre-existing lung disease, represented by diffuse interstitial changes on chest X-ray, and mild bronchial asthma in two RA patients and by pulmonary silicosis in the patient with PsA may account for a predisposition to the development of MTX pneumonitis.",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate-induced pneumonitis in patients with rheumatoid arthritis and psoriatic arthritis: report of five cases and review of the literature.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On the other hand, MTX-induced pneumonitis seems to be very rare in psoriatic arthritis (PsA).",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Our review of 194 RA patients and 38 PsA patients receiving MTX has identified four RA patients and one PsA patient with MTX-induced pneumonitis, giving a prevalence of 2.1% and 0.03%, respectively.",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Pneumonitis is emerging as one of the most unpredictable and potentially serious, adverse effects of treatment with MTX.",Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The presence of a lymphocyte alveolitis with a predominance of CD4+ T cells in 3 RA patients and CD8+ T cells with a concomitant increase in neutrophils in another case suggests that immunologically mediated reactions may be one damage mechanism in MTX-induced pneumonitis.,Pneumonitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A retrospective epidemiological study of deaths from hepatic angiosarcoma (HAS) in the U.S. showed that during 1964--74 there were 168 such cases, of which 37 (22%) were associated with previously known causes (vinyl chloride, 'Thorotrast', and inorganic arsenic) and 4 (3.1%) of the remaining 131 cases with the use of androgenic-anabolic steroids.",Hepatic angiosarcoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Recent studies have shown that under experimental conditions ferrous sulfate may reduce the gastrointestinal absorption of orally administered levothyroxine sodium in patients with primary hypothyroidism.,Malabsorption
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient who became hypothyroid while taking ferrous sulfate.,Hypothyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, as the use of hepatitis B vaccination is growing, adverse side effects, including mental nerve neuropathy, should be observed with an increased frequency.",Numb chin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mental nerve neuropathy as a result of hepatitis B vaccination.,Numb chin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although its side effects are few, tamoxifen increases the incidence of proliferative lesions of the endometrium, which theoretically should be preventable with progestational agents.",Endometrial hyperplasia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASES: Two postmenopausal women treated with tamoxifen and progestational agents for breast carcinoma developed uterine enlargement and intermittent spotting.,Postmenopausal haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: The value of multihormonal therapy in breast carcinoma is not established, and the addition of progestogens to tamoxifen may not reduce of developing endometrial lesions, including carcinoma.",Neoplasm malignant
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Thoracoscopic biopsy to confirm metastasis revealed instead fibrotic lesions apparently attributable to bleomycin or cyclophosphamide.,Fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An elderly man with procainamide hydrochloride-induced lupus syndrome had a circulating anticoagulant against factor XI and a biologic false-positive (BFP) test result for syphilis.,Systemic lupus erythematosus syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Circulating anticoagulant in the procainamide-induced lupus syndrome.,Systemic lupus erythematosus syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinical signs of hypermagnesemia are an uncommon complication following oral administration of magnesium sulfate.,Hypermagnesaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Establishment of diuresis with fluids and IV administration of calcium may provide successful treatment of magnesium toxicosis in horses.,Hypermagnesaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Magnesium toxicosis in two horses.,Hypermagnesaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Overdose of magnesium sulfate in combination with renal insufficiency, hypocalcemia, or compromise of intestinal integrity may predispose horses to magnesium toxicosis.",Hypermagnesaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CASE SUMMARIES: In each case, the patients were treated over 5 years with lovastatin and developed rhabdomyolysis that coincided with the completion of a prescribed regimen of a newer macrolide antibiotic.",Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: The risk of drug-induced rhabdomyolysis due to the potential interaction between lovastatin and azithromycin or clarithromycin should be considered before the concomitant use of these agents.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"DISCUSSION: Rhabdomyolysis is a clinical syndrome resulting from the destruction of skeletal muscle that may progress to renal failure Several drugs have been associated with rhabdomyolysis, including lovastatin, a hydroxymethylglutaryl-coenzyme A reductase inhibitor.",Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Erythromycin is a macrolide antibiotic that may increase the risk of lovastatin-induced rhabdomyolysis.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe two cases of rhabdomyolysis in patients taking lovastatin that were precipitated by the use of the newer macrolide antibiotics clarithromycin and azithromycin.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To our knowledge, these cases are the first published reports of lovastatin-induced rhabdomyolysis associated with azithromycin and clarithromycin.",Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These cases were considered unusual in light of the short delay of their onset after initiation of immunosuppressive therapy and their fulminant course: 3 of these patients died of PCP occurring during the first month of treatment with prednisone.,Death
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the specifics of 12 cases of severe hypertension after the intraoperative use of topical phenylephrine, submucosal epinephrine, or both.",Hypertensive urgency
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute leukaemia during tamoxifen therapy.,Acute leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tamoxifen is suggested to be carcinogenic both through direct genotoxic and epigenetic mechanisms.,Carcinogenicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report two cases that developed acute myeloid leukaemia (AML) during tamoxifen therapy for breast cancer.,Acute myeloid leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Relapse in the external auditory canal of acute promyelocytic leukemia after treatment with all-trans retinoic acid.,Acute promyelocytic leukaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cutaneous reactions to propylthiouracil and methimazole occur in 3%-5% of adults.,Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Generalized maculopapular and papular purpuric eruptions are perhaps the most common thionamide-induced reactions.,Rash maculo-papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Propylthiouracil-induced cutaneous vasculitis.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The observation of cutaneous vasculitis during administration of propylthiouracil suggested that clinical awareness of this complication should be of considerable importance.,Cutaneous vasculitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 2-year-old mentally retarded boy with frontal lobe epilepsy presented with an episode that resembled heat stroke during the administration of zonisamide.,Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Children receiving zonisamide should be monitored for oligohidrosis and the development of neurological symptoms associated with an elevation of body temperature.,Neurological symptom
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Heat stroke-like episode in a child caused by zonisamide.,Heat stroke
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure in a patient receiving treatment with suramin.,Acute Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure should be recognized as a potential complication of suramin treatment.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Other potential causes of renal failure were not present in our patient and his renal function gradually recovered with the cessation of suramin treatment.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient with metastatic prostate cancer who developed nonoliguric renal failure during treatment with suramin.,Renal failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clozapine induced polyserositis.,Polyserositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the case of a patient who developed polyserositis (pericardial effusion, pleural effusion, and pericarditis) after being started on clozapine, and whose symptoms remitted upon discontinuation of clozapine.",Pericardial effusion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thirty-six patients with AL received, in a three-month period, 51 cycles of combined chemotherapy which included, in all of them, cytosine arabinoside (ARA-C); among them, along with myelosuppression, five experienced fever, infectious complications, gastrointestinal tract symptoms and severe myalgias.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: We believe this to be the first reported case of rhGH-induced hypercalcemia in an HIV-infected patient.,Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypercalcemia in an AIDS patient treated with growth hormone.,Hypercalcemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The hypercalcemia responded to discontinuation of rhGH and a single dose of intravenous pamidronate disodium and has not recurred in 8 months of follow-up.,Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a male patient with advanced AIDS who developed hypercalcemia 2 weeks after institution of rhGH therapy.,Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hypersensitivity reactions to cisplatin following multiple uncomplicated courses: a report on two cases.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.",Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report an unusually short lived and asymptomatic episode of severe cisplatin-induced renal tubular salt wasting in a fit 41-year-old patient with malignant teratoma.,Renal tubular acidosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinicians should include phenolphthalein in their list of possible causes of drug-induced TEN.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: Phenolphthalein is the active ingredient in several over-the-counter laxative preparations and has only rarely been reported to cause TEN.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of phenolphthalein-induced toxic epidermal necrolysis (TEN) in a patient maintained on several other medications more commonly known to be associated with TEN.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Phenolphthalein-induced toxic epidermal necrolysis.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The patient's previous rash and the temporal relation of this event and the ingestion of phenolphthalein, as well as the similarity of this case to other reports, point to phenolphthalein as the cause of TEN in this patient.",Rash
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"During clarithromycin coadministration, four out of the seven patients developed moderate-to-severe toxic symptoms of carbamazepine, such as drowsiness, dizziness, and ataxia, which resolved within 5 days after clarithromycin discontinuation.",Ataxia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"As far as we know, this is the first case report of acute hemorrhagic gastritis associated with AZ intoxication.",Gastritis haemorrhagic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We experienced a case of chronic renal failure in a patient suffering from acute hemorrhagic gastritis associated with AZ intoxication.,Gastritis haemorrhagic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In association with this tocolysis, urinary calculus of magnesium ammonium phosphate occurred at 34 weeks gestation.",Calculus urinary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Magnesium tocolysis as the cause of urinary calculus during pregnancy.,Calculus urinary
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Danazol induced thrombocytopenia.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"On the next day, after a total dose of only 600 mg of danazol, gingival bleeding and purpura occurred.",Gingival bleeding
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We diagnosed this case as danazol induced thrombocytopenia.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It occasionally accompanies the heparin-associated thrombocytopenia and thrombosis syndrome.,Thrombocytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Skin necrosis is a rare complication of subcutaneous heparin therapy that usually occurs at injection sites.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Skin necrosis secondary to low-molecular weight heparin in a patient with antiphospholipid antibody syndrome.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient with the antiphospholipid syndrome who had skin necrosis develop from low-molecular weight heparin therapy at sites distant from injection sites.,Skin necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of contact dermatitis due to sodium bisulfite in an ophthalmic solution.,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Therefore, we diagnosed her eruption as contact dermatitis due to sodium bisulfite.",Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of contact dermatitis due to sodium bisulfite in Tathion eye drops.,Dermatitis contact
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute pancreatitis after long-term 5-aminosalicylic acid therapy.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Acute pancreatitis is a known, although rare, complication of mesalamine treatment.",Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A rechallenge, performed in both patients, confirmed the diagnosis of mesalamine-induced pancreatitis.",Pancreatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,These case reports provide evidence that 5-aminosalicylic acid may induce acute pancreatitis after long term treatment.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe two cases of acute pancreatitis that occurred after long term mesalamine therapy for ulcerative colitis.,Pancreatitis acute
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 35-year-old nephrotic man developed acute renal failure with serum creatinine to 1543 micromol/l after a month of therapy with enalapril.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute renal failure with severe tubulointerstitial changes in a patient with minimal change nephrotic syndrome treated with enalapril.,Acute kidney injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Early ritonavir-induced maculopapular eruption.,Rash maculo-papular
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report 2 cases of maculopapular eruption and fever in patients infected with human immunodeficiency virus (HIV) on the 2nd day of first administration of ritonavir, a protease inhibitor.",Pyrexia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Nephropathy caused by methicillin therapy for staphylococcal septicemia.,Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Review of the literature relating to methicillin-induced nephropathy suggests a hypersensitivity origin for this disorder, but immunologic and ultrastructural investigation to date has failed to elucidate pathogenesis.",Nephropathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 25-year-old woman sought medical attention because of iliocaval manifestations of retroperitoneal fibrosis while she was taking methysergide.,Retroperitoneal fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methysergide-induced retroperitoneal fibrosis: successful outcome and two new laboratory features.,Retroperitoneal fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Vitiligo associated with alpha-interferon in a patient with chronic active hepatitis C.,Vitiligo
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of vitiligo that occurred during the second month of interferon alpha 2a therapy for chronic active hepatitis C.,Vitiligo
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case is reported of an elderly woman who developed febrile agranulocytosis several weeks after commencing ticlopidine but who had a favorable outcome after cessation of that drug and treatment with filgastrim.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Agranulocytosis associated with ticlopidine: a possible benefit with filgastim.,Agranulocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Ticlopidine is an oral antiplatelet agent frequently utilized in the treatment of cerebrovascular disease and is rarely associated with severe bone marrow suppression, typically aplastic anemia.",Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Hemodialysis was also shown to reverse ifosfamide-related neurotoxicity.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ifosfamide-associated neurotoxicity was noted within hours of drug administration and improved rapidly following hemodialysis.,Neurotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 55-year-old woman developed symptoms suggestive of hepatitis 12 weeks after first receiving methyldopa for hypertension.,Hepatitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methyldopa-induced liver injury.,Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Such a rapid and relentless progression of methyldopa-induced liver injury is undoubtedly rare, but it may be prevented by careful supervision of patients who exhibit liver function abnormalities early in the course of therapy.",Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute respiratory depression as a complication of nebulised morphine.,Respiratory depression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Approximately 15 min after the first administration of nebulised morphine the patient became markedly bradypneic (respiratory rate: 4-5 bpm), hypotensive (BP 70/40 mmHg), and responded only partially to command.",Bradypnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,PURPOSE: To present a case of respiratory depression following the administration of nebulised morphine.,Respiratory depression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute dystonia with thalamic and brainstem lesions after initial penicillamine treatment in Wilson's disease.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"From these data, acute generalized dystonia with brainstem and thalamic lesions may occur in WD patients after an initial d-penicillamine therapy.",Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We reported 3 patients who developed acute generalized dystonia and akinetic rigid syndrome following an initial therapy with d-penicillamine 125-500 mg daily.,Dystonia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Ballistic movements due to ischemic infarcts after intravenous heroin overdose: report of two cases.,Ballismus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Patient 1 presented bilateral ballism 1 week after intravenous heroin injection.,Ballismus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Stroke is an infrequent but recognized complication of heroin addiction.,Cerebrovascular accident
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two heroin addicts, aged 34 and 19 years, developed ballistic movements after intravenous heroin overdose.",Ballismus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A MEDLINE search identified all the reported cases of hypersensitivity reactions to cyclosporine.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylaxis to intravenous cyclosporine and tolerance to oral cyclosporine: case report and review.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,BACKGROUND: Hypersensitivity reactions to cyclosporine are rare.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Hypersensitivity reactions to cyclosporine are due to Cremophor EL.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Fortunately, a hypersensitivity reaction to one formulation of cyclosporine does not preclude use of a different formulation.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,METHODS: We report a patient who had an anaphylactic reaction during the intravenous infusion of cyclosporine.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To investigate the mechanisms involved in hypersensitivity reactions to cyclosporine and determine the feasibility of future cyclosporine use.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The literature search revealed 22 cases of hypersensitivity reaction to cyclosporine.,Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prothipendylhydrochloride-induced priapism: case report.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present the first case of a patient with priapism after oral intake of the phenothiazine prothipendylhydrochloride.,Priapism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The chemotherapeutics, including vincristine, actinomycin D, and epirubicin in case 1 and vincristine and actinomycin D in case 2, were given before the hepatotoxicity developed.",Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We conclude that vincristine and actinomycin D were the cause of this rare from of hepatotoxicity and that chemotherapy for the underlying malignant disease could be given safely after clinical recovery.,Hepatotoxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because the combination of bleomycin and vinca alkaloids is commonly used for the treatment of AIDS-related Kaposi's sarcoma, clinicians should be aware of the risk of provoking acral necrosis in patients who develop Raynaud's phenomenon under chemotherapy.",Necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this report, one patient who developed gangrene after bleomycin and vincristine/vinblastine chemotherapy for AIDS-related Kaposi's sarcoma and another HIV-infected patient who exhibited symptoms of severe Raynaud's phenomenon related to the same regimen are presented.",Gangrene
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Development of essential thrombocythemia in a patient treated with interferon alfa and pentostatin for hairy cell leukemia.,Thrombocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Second cancers including various types of hematological malignancy have been reported in patients with hairy cell leukemia treated with chemotherapy or interferon alfa.,Haematological malignancy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Effect of beta-blockade on symptomatic dexamethasone-induced hypertrophic obstructive cardiomyopathy in premature infants: three case reports and literature review.,Hypertrophic cardiomyopathy
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"One patient had a lower average heart rate and two patients had lower average mean blood pressure values during propranolol treatment, none of which was clinically significant.",Bradycardia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CASE SUMMARY: A 25-year-old postpartum white woman developed multiple watery stools and abdominal cramping on day 6 of therapy with clindamycin vaginal cream for bacterial vaginosis.,Abdominal pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clostridium difficile toxin-induced colitis after use of clindamycin phosphate vaginal cream.,Clostridium difficile colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: This report indicates clindamycin phosphate vaginal cream as the most probable cause of CDIC due to the temporal relationship between the occurrence of diarrhea and clindamycin administration, lack of concomitant medications, and documentation of C. difficile toxin.",Clostridium difficile colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,DISCUSSION: No published clinical studies in patients receiving clindamycin vaginal cream for bacterial vaginosis have documented C. difficile toxin in stool samples of patients with diarrhea.,Clostridium test positive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of toxin-positive Clostridium difficile-induced colitis (CDIC) after use of clindamycin phosphate vaginal cream.,Clostridium difficile colitis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 54-year-old man developed TEN 4 weeks after beginning lamotrigine for complex partial seizures related to a glioblastoma multiforme brain tumor.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Administration of lamotrigine, especially in combination with valproic acid, may lead to the development of TEN.",Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Fatal toxic epidermal necrolysis related to lamotrigine administration.,Toxic epidermal necrolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"To date, eight cases of TEN and one of SJS related to lamotrigine administration have been reported in the literature.",SJS-TEN overlap
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A syndrome of increased affect in response to risperidone among patients with schizophrenia.,Affective disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Six of 13 outpatients with schizophrenia who participated in a ten-week open trial of risperidone had an initial good response to the medication followed by development of intolerable affect, including feelings of agitation and depression and periods of crying and insomnia.",Depression
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The authors suggest that risperidone may increase affect in patients with schizophrenia and that some patients, especially those with anxiety, may have difficulty managing the increase.",Inappropriate affect
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 28 year old white schizophrenic male has been under risperidone monotherapy for about one year when he developed dyskinetic movements.,Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Risperidone-induced tardive dyskinesia.,Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This report presents a potential case of risperidone-induced tardive dyskinesia.,Tardive Dyskinesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Increased ocular pressure in two patients with narrow angle glaucoma treated with venlafaxine.,Intraocular pressure increased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 61-year-old man developed clinical lupus syndrome with positive antinuclear antibody, positive lupus erythematosus (LE) cell preparation, and diffuse proliferative glomerulonephritis following 26 months of procainamide therapy.",Systemic lupus erythematosus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature.,Glomerulonephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a 76-year-old man who developed an acute blistering eruption following high-dose penicillin treatment for pneumococcal septicaemia.,Dermatitis bullous
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A case of prolonged suxamethonium apnoea successfully terminated by the infusion of a commercial preparation of serumcholinesterase is reported.,Apnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Suxamethonium apnoea terminated with commercial serumcholinesterase.,Apnoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Cardiac arrest associated with sulprostone use during caesarean section.,Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We postulate that the bolus of sulprostone resulted in possible coronary spasm that resulted in cardiac arrest.,Cardiac arrest
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Prolonged prostate-specific antigen response in flutamide withdrawal syndrome despite disease progression.,flutamide Drug withdrawal syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Anaphylactic reaction to oral prednisone: a case report and review of the literature.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe the case of a nonatopic 17-year-old girl with bronchial asthma and aspirin intolerance who developed a dramatic anaphylactic reaction to oral prednisone.,Anaphylactic reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"METHODS: Double-blind, placebo-controlled titrated oral challenges with pancreatic enzymes resulted in definite vomiting within 1 to 1.5 hours after challenges with Viokase and Pancrease MT 16, but not with placebo.",Vomiting
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"She was treated with Pancrease MT 16, but had consistent vomiting 1 to 2 hours after administration of enzymes.",Vomiting
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The vomiting occurred on switching to different pancreatic enzymes preparations, ie, Creon 10, Viokase, and Pancrease MT 16.",Vomiting
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Acute valproate ingestion induces symptomatic methemoglobinemia.,Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report for the first time the development of symptomatic methemoglobinemia after an acute ingestion of divalproex sodium (Depakote), resulting in serum concentrations 10 times greater than the therapeutic range.",Methaemoglobinaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In rare cases mitomycin C (MMC) may induce cancer-associated hemolytic uremic syndrome, which is characterized by hemolytic anemia, thrombocytopenia and progressive renal failure.",Haemolytic anaemia enzyme specific
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Mitomycin C-related hemolytic uremic syndrome in cancer patients.,Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of MMC-related hemolytic uremic syndrome, and discuss the etiologic parameters, clinical aspects, prognosis and treatment modalities of this severe syndrome.",Haemolytic uraemic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CD4 T-lymphocyte depletion, myelosuppression, and subsequent severe infections are the major side effects of fludarabine phosphate therapy.",Lymphocyte count decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe respiratory syncytial virus pulmonary infection in a patient treated with fludarabine for chronic lymphocytic leukemia.,Respiratory syncytial virus infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report here on a heretofore undescribed respiratory syncytial virus (RSV) infection in a patient with a long-standing history of refractory CLL that was treated with fludarabine phosphate.,Respiratory syncytial virus infection
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Serotonin syndrome induced by transitioning from phenelzine to venlafaxine: four patient reports.,Serotonin syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Although this G-CSF-driven leucocytosis was alarming it did not appear to have adversely affected the patient's prognosis.,Leukocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Leukaemoid monocytosis in M4 AML following chemotherapy and G-CSF.,Leukaemoid reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a patient with M4 AML treated with standard chemotherapy followed by G-CSF who developed marked monocytosis on day 8 of G-CSF therapy.,Monocytosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Case 2 demonstrated after 40 months on chlorambucil the presence of a balanced translocation, t (1;5) (p36;q31) in 90% of the cells.",Autosomal chromosome anomaly
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Chromosome abnormalities after chlorambucil therapy of polycythaemia vera.,Acquired chromosomal abnormality
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Administration of steroid and decreasing the dose of PTU produced a good clinical response and the ANCA disappeared.,Antineutrophil cytoplasmic antibody
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis associated with propylthiouracil therapy.,Antineutrophil cytoplasmic antibody
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A teenage girl with crescentic glomerulonephritis had antineutrophil cytoplasmic antibody (ANCA) detected after she had received propylthiouracil (PTU) for hyperthyroidism without cutaneous vasculitis.,Antineutrophil cytoplasmic antibody
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It was concluded that ANCA is closely related to the pathogenesis of crescentic glomerulonephritis and that treatment with PTU appeared to induce ANCA.,Antineutrophil cytoplasmic antibody
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A drug interaction between zafirlukast and theophylline.,Drug interaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Attempts were made to stop and then restart the theophylline therapy at progressively lower doses; however, with each attempt, the patient's reaction to the drug became more toxic, with serum theophylline levels ranging between 99.9 and 149.9 micromol/L (18 and 27 microg/mL).",Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present the first case (to our knowledge) of a potentially serious drug-drug interaction between zafirlukast and theophylline.,Drug interaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 21-year-old patient developed rhabdomyolysis during his nineteenth week of treatment with clozapine for drug-resistant schizophrenia.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clozapine is speculated to cause rhabdomyolysis in patients with defective calcium-activated K+ channels.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Rhabdomyolysis associated with clozapine treatment in a patient with decreased calcium-dependent potassium permeability of cell membranes.,Rhabdomyolysis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe children and adolescents with chronic hematologic and oncologic diseases who exhibited drug-seeking behavior or anticholinergic symptoms with the use of diphenhydramine.,Anticholinergic syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Excluding other causes, Pentasa-associated pancytopenia was considered.",Pancytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"He developed fever, nausea, diarrhea, and malaise and stopped taking on the third day after commencing Pentasa.",Diarrhoea
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pancytopenia associated with 5-aminosalicylic acid use in a patient with Crohn's disease.,Pancytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report a case of pancytopenia in a 23-year-old man with Crohn's disease who was treated with 5-aminosalicylic acid (Pentasa; Nisshin, Tokyo, Japan) 3.0 g/day.",Pancytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We describe a renal transplant recipient maintained on cyclosporine and prednisone developing Nocardia Asteroides brain abscess.,Nocardiosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Young children undergoing cisplatin chemotherapy are known to be at risk for progressive sensorineural hearing loss.,Deafness neurosensory
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A 47 year-old woman who had a 4-year history of intramuscular pentazocine injections in the lower extremities, developed gradual stiffness and weakness of the lower extremities.",Musculoskeletal stiffness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Caution in longterm usage and early recognition of pentazocine toxicity as a neuromuscular complication are important in order to prevent irreversible drug-induced fibrous myopathy and localized neuropathy.,Muscle fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pentazocine-induced fibrous myopathy and localized neuropathy.,Muscle fibrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In two of these cases akathisia resolved after withdrawal of olanzapine and substitution by a classical or an atypical neuroleptic agent, respectively.",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Like other atypical neuroleptics olanzapine is considered to show a reduced prevalence of extrapyramidal side effects when compared to classical neuroleptic drugs.,Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,One should therefore be aware of possible extrapyramidal side effects with olanzapine that are reduced compared to classical neuroleptic drugs but not completely eliminated.,Extrapyramidal disorder
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Severe akathisia during olanzapine treatment of acute schizophrenia.,Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report on three patients with acute schizophrenia, who developed severe akathisia during treatment with olanzapine (20-25 mg/d).",Akathisia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Seizures occurred in two patients with probable Alzheimer's disease who were receiving long-term treatment with metrifonate, an irreversible acetylcholinesterase inhibitor.",Seizure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, 1 eye had vitreous hemorrhage after repeated injections of tPA.",Vitreous haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"However, repeated intracameral tPA injections may cause unwanted complications such as vitreous hemorrhage.",Vitreous haemorrhage
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although praziquantel administration may have been effective in killing the parasite in both patients, we are concerned about the production of marked inflammation as a result of treatment.",Inflammation
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"NMS is a drug-related response to various medications, such as Haloperidol, which the patient was receiving.",Neuroleptic malignant syndrome
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methimazole-induced aplastic anemia in third exposure: successful treatment with recombinant human granulocyte colony-stimulating factor.,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We present a case of a 58-year-old female patient with Graves' disease who developed AA in the third exposure to methimazole (MMI).,Aplastic Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"FSGS induced by Adriamycin (Pharmacia & Upjohn, Columbus, OH) has been observed experimentally in rats.",Focal segmental glomerulosclerosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The case demonstrates that hypersensitivity reaction to pranlukast and resultant ATIN is possible, and that periodic urine testing in patients receiving pranlukast should be considered.",Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Tubulointerstitial nephritis induced by the leukotriene receptor antagonist pranlukast.,Tubulointerstitial nephritis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Within 6 months of pranlukast withdrawal, anemia resolved and urinary sediment and renal function normalized.",Anaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 65-year-old woman with angina pectoris presented with syncope after sublingual ingestion of isosorbide dinitrate (5 mg).,Syncope
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Elderly patients for whom nitrate has been prescribed should be warned of the occurrence of hypotension, leading to unconsciousness.",Hypotension
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In a postural challenge test after administration of isosorbide dinitrate (5 mg), blood pressure decreased from 120/67 to 65/35 mmHg, followed by syncope with a sudden decrease in pulse rate from 85 to 60 beats/min.",Blood pressure decreased
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Syncope in a 65-year-old woman after nitrate ingestion.,Syncope
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Three diabetic cases of acute dizziness due to initial administration of voglibose.,Dizziness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We observed 3 diabetic patients with intolerable dizziness followed by nausea and vomiting immediately after an initial administration of the alpha-glucosidase inhibitor, voglibose.",Dizziness
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Naproxen-associated sudden sensorineural hearing loss.,Deafness neurosensory
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Naproxen is a commonly used nonsteroidal anti-inflammatory drug (NSAID) whose side effects include tinnitus and transient hearing loss.,Tinnitus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,This article reports the case of an otherwise healthy patient who experienced permanent sensorineural hearing loss after a brief course of naproxen and reviews the literature on NSAID-related permanent sensorineural hearing loss.,Deafness neurosensory
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Dental and gingival pain as side effects of niacin therapy.,Gingival pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The cause of these previously unreported side effects of niacin therapy is uncertain but may be related to prostaglandin-mediated vasodilatation, hyperalgesia of sensory nerve receptors, and potentiation of inflammation in the gingiva with referral of pain to the teeth.",Hyperaesthesia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Two 65-year-old white men with coronary heart disease, given niacin therapy for dyslipidemia for 5 months, developed intense dental and gingival pain that was associated with increases in dose and that was relieved with discontinuance of niacin treatment.",Gingival pain
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Although major hazards of treatment of hypophosphatemic osteomalacia with phosphate and calcitriol are secondary hyperparathyroidism and vitamin D intoxication, potassium loss also should be kept in mind.",Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,High-dose phosphate treatment leads to hypokalemia in hypophosphatemic osteomalacia.,Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,It was concluded that potassium loss occurred by a non-renal (intestinal) route in phosphate-induced hypokalemia.,Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Progressive hypokalemia developed during phosphate treatment.,Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"The mechanism of the decrease in plasma potassium induced by phosphate treatment was investigated in a 24-year-old hypertensive patient with hypophosphatemic osteomalacia, who was the youngest of four patients, belonging to a 23 number kindred of five generations.",decrease in plasma potassium
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Transtubular potassium gradient (TTKG) also decreased and an inverse correlation was found between TTKG and doses of phosphate (r = -0.37; p < 0.02; N = 38).,Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Alveolar-interstitial pneumopathy after gold-salts compounds administration, requiring mechanical ventilation.",Interstitial lung disease
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The pulmonary toxicity of gold salts is an uncommon cause of life-threatening respiratory failure.,Pulmonary toxicity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report a case of severe respiratory failure due to gold salt toxicity in a patient suffering from rheumatoid arthritis requiring mechanical ventilation.,Respiratory failure
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"As this relapse coincided with development of a strong delayed-type hypersensitivity response to tuberculin and improved after treatment with the anti-inflammatory agent oxpentifylline, it was probably caused by restoration of pathogen-specific cellular immunity.",Hypersensitivity
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion.",Glycosuria
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%.,Hyperglycaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"After 1 week of nefazodone therapy the patient experienced headache, confusion, and ""gray areas"" in her vision, without abnormal ophthalmologic findings.",Confusional state
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Coadministration of antidepressant agents such as nefazodone, or any other drug that inhibits the CYP3A4 isoenzyme subfamily, should be anticipated to interfere with tacrolimus metabolism.",Drug interaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Interaction between tacrolimus and nefazodone in a stable renal transplant recipient.,Drug interaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We suspect that nefazodone inhibits metabolism of tacrolimus.,Drug interaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,We report the case of intoxication of a 41-year-old female patient suffering from major depression with mirtazapine complicated by severe hypothermia.,Poisoning
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: We report a case of the use of pamidronate for significant hypercalcemia secondary to acute vitamin D poisoning.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pamidronate therapy should be considered in patients with hypercalcemia secondary to acute vitamin D poisoning.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The patient was initially treated with hydration and furosemide but developed congestive heart failure.,Cardiac failure congestive
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The use of pamidronate for hypercalcemia secondary to acute vitamin D intoxication.,Toxicity to various agents
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report the use of pamidronate for acute, severe hypercalcemia secondary to iatrogenic vitamin D poisoning.",Hypercalcaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A 40-year-old man with a long standing history of rheumatoid arthritis was treated with MTX over a 6 month period and developed an overwhelming hepatic necrosis.,Hepatic necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Methotrexate-induced hepatic necrosis requiring liver transplantation in a patient with rheumatoid arthritis.,Hepatic necrosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"MTX-induced hepatic injury and liver enzyme elevations have been demonstrated after treatment of leukemia, gestational disease and during treatment of psoriasis and rheumatoid arthritis.",Drug-induced Liver injury
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Clinicians should be aware of the possibility that vinorelbine may cause SIADH and possibly hypokalemia.,Hypokalaemia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"CONCLUSIONS: Because of its structural similarity to the other vinca alkaloids, vinorelbine is believed to be responsible for SIADH in our patient.",Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To describe onset of syndrome of inappropriate antidiuretic hormone (SIADH) associated with vinorelbine therapy for advanced breast cancer.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Syndrome of inappropriate antidiuretic hormone associated with vinorelbine therapy.,Inappropriate antidiuretic hormone secretion
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Pirmenol hydrochloride-induced QT prolongation and T wave inversion on electrocardiogram during treatment for symptomatic atrial fibrillation.,Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Thus, an immunological mechanism might be involved in the mechanism of pirmenol-induced QT prolongation and T wave inversion on the electrocardiogram.",Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We report on a 56-year-old female who exhibited drug refractory paroxysmal atrial fibrillation, in which marked prolongation of the QT interval and T wave inversion on electrocardiogram was demonstrated reproducibly shortly after the administration of oral pirmenol therapy.",Torsade de pointes
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Disseminated muscular cysticercosis with myositis induced by praziquantel therapy.,Myositis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"We describe a case of disseminated muscular cysticercosis followed by myositis (fever, diffuse myalgia, weakness of the lower limbs, and inflammatory reaction around dying cysticerci) induced by praziquantel therapy, an event not described previously.",Myalgia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Massive subfascial hematoma after alteplase therapy for acute myocardial infarction.,Haematoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Physicians should be aware of the possible association between the use of alteplase and the development of subfascial hemorrhage.,Haematoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The authors report a case of a patient who received alteplase for acute myocardial infarction and developed spontaneous subfascial hematoma without any evidence of direct trauma.,Haematoma
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,The development of cutaneous ecchymosis associated with a sudden fall in hemoglobin after the administration of alteplase should strongly suggest the possibility of diffuse subfascial hematoma.,Ecchymosis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,A fatal case of pancytopenia due to levomepromazine.,Pancytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"A fatal pancytopenia occurred in a patient with an history of depression with hypomanic rebounds, admitted for a manic episode and treated with levomepromazine, diazepam and lithium carbonate.",Pancytopenia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Amiodarone-induced thyrotoxicosis associated with thyrotropin receptor antibody.,Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Among 12 thyrotoxic patients, a patient with arrhythmogenic right ventricular dysplasia, who had been taking amiodarone for 4 years, developed thyrotoxicosis with subacute onset, accompanied by transiently positive thyrotropin (TSH) receptor antibody (TRAb), or thyrotropin-binding inhibiting immunoglobulin (TBII).",Hyperthyroidism
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Since amiodarone was first marketed in 1992 in Japan, the incidence of amiodarone-induced thyrotoxicosis (AIT) has been increasing.",Autoimmune thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"These in vitro findings and clinical course suggest that TRAb/TBII without thyroid-stimulating activity may develop in patients with amiodarone-induced destructive thyroiditis, as reported in patients with destructive thyroiditis, such as subacute and silent thyroiditis.",Thyroiditis
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSION: Lipoid pneumonia as a result of mineral oil aspiration still occurs in the pediatric population.,Pneumonia lipoid
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lipoid pneumonia: a silent complication of mineral oil aspiration.,Pneumonia lipoid
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Our case points to the need for increased awareness by the general pediatricians of the potential hazards of mineral oil use for chronic constipation.,Adverse event
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,An unusual cause of burn injury: unsupervised use of drugs that contain psoralens.,Photosensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Because psoralens sensitize skin to ultraviolet A light, phototoxic reactions are the most frequent adverse effect of this treatment.",Photosensitivity reaction
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"In this article, we present the case of a vitiligo patient who was admitted to our facility with an intense burn after the topical use of 8-methoxypsoralen solution as a suntanning agent.",Thermal burn
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Sunburn may sometimes be a major injury in psoralen users because high doses or inappropriate use of the drug may render the skin extremely sensitive.,Dermatitis allergic
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,CONCLUSIONS: Metoclopramide may cause reversible nonthrombocytopenic vascular-type palpable purpura.,Palpable purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,OBJECTIVE: To report a case of reversible nonthrombocytopenic palpable purpura associated with metoclopramide.,Palpable purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Reversible nonthrombocytopenic palpable purpura associated with metoclopramide.,Palpable purpura
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,Lithium treatment was terminated in 1975 because of lithium intoxication with a diabetes insipidus-like syndrome.,Diabetes insipidus
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Eosinophilia caused by clozapine was observed in challenge, preceded by a faster neutrophil production and consecutive decrease (z = 2.27, p = 0.01).",Eosinophilia
Map Adverse Drug Events (ADEs) mentioned in text data to their most relevant Preferred MeDDRA terms.,"Eosinophilia has been encountered from 0.2 to 61.7% in clozapine-treated patients, mostly with a transient course and spontaneous remission.",Eosinophilia
,Successful challenge with clozapine in a history of eosinophilia.,Eosinophilia