tokens: Patients were categorized into three groups : A - NC with liver failure ( N = 8) : tyrosinemia type I ( n = 2 ) , classic galactosemia ( n = 5 ) , mitochondrial DNA depletion syndrome ( n = 1 ) ; B - NC evolving with chronic liver disease ( N = 5 ): argininemia ( n = 2 ) ; mitochondrial cytopathy ( n = 1 ) ; congenital disorders of glycosylation type Ia ( n = 1 ) ; Zellweger syndrome ( n = 1 ) ; and C - transient NC ( N = 3 ): Niemann - Pick type C ( n = 2 ) , citrullinemia type II ( n = 1).Conclusion : MLD presenting with NC can be categorized into three main clinical phenotypes of liver injury .