tokens: Since aPL have the potential to cross the placental barrier , and since the pediatric population is prone to infections , re - testing for their positivity is essential to specify their role in cerebrovascular thrombosis . In this review , we aimed at assessing the prevalence of aPL , criteria or non - criteria , in neonatal and childhood ischemic stroke and sinovenous thrombosis trying to find an association between aPL and cerebrovascular thrombosis in the neonatal and pediatric population .