tokens: Common neuropathological findings in the 184 patients reviewed include microglial activation ( 42.9 % ) with microglial nodules in a subset ( 33.3 % ) , lymphoid inflammation ( 37.5 % ) , acute hypoxic - ischemic changes ( 29.9 % ) , astrogliosis ( 27.7 % ) , acute / subacute brain infarcts ( 21.2 % ) , spontaneous hemorrhage ( 15.8 % ) , and microthrombi ( 15.2 % ) .