tokens: Six patients had propionic academia with a prevalence of 1:310 200 , 7 had isovaleric academia ( 1:265 900 ) , 6 had glutaric academia type 1 ( 1:310 200 ) , 27 had 3 - methylcrotonyl - CoA carboxylase deficiency ( MCC , 1:68 900 ) , 1 had 3 - hydroxy-3 - methylglutaric aciduria ( 1:1 861 300 ) , 2 had β0 - ketothiolase deficiency ( 1:960 600 ) , and 3 had biotinidase deficiency / holocarboxylase synthetase deficiency ( 1:620 400 ) .