text:   kinetics",7,"['.@Rebecca_Wade_C , @DariaKokh  and I wrote a review of computational methods to study ligand-protein binding kinetics. We assessed the performance of methods considering two benchmark systems, T4 lysozyme (T4L) and N-HSP90. (1/3)\n@HITStudies  #compchem\n<LINK> <LINK>', '@Rebecca_Wade_C @DariaKokh @HITStudies The figure below shows the times required for different methods to simulate complexes with different exp. residence times (RT). In the last two years many methods to compute relative RT were published. An increase of four orders of magnitude in exp. RT leads to a smaller,  (2/3) https://t.co/xfMw29mTgi', '@Rebecca_Wade_C @DariaKokh @HITStudies one order of magnitude increase in comp. time.\nFor T4L, results indicate that good RT estimation can be achieved without exhaustive path sampling so long as the most probable paths are sampled (table below).\nAnother highlight: two works aiming at computing RT prospectively. (3/3) https://t.co/Eaom4mwQPN', '@_Maicol_ @Rebecca_Wade_C @DariaKokh @HITStudies thanks!\n😊', '@sowmyaindrakum1 @Rebecca_Wade_C @DariaKokh @HITStudies what i showed you in your visit is related, but not the same thing.', '@Jmondal_tifrh @Rebecca_Wade_C @DariaKokh @HITStudies thanks!\n😊', '@Herr_Flow @Rebecca_Wade_C @DariaKokh @HITStudies you are welcome!\n😀\nis the arXiv paper published? send me the link, so I can correct the citation later. our work is under review on COSB right now.']",20,02,1361