tokens: The authors conclude by affirming the undoubted efficacy of the anabolizing steroids in experimental myopathic disease , but they have reservations as to the transfer of the results into the human field , where high dosage cannot be carried out continuously because of the effects of the drug on virility ; because the tissue injury too often occurs at an irreversible stage vis - a - vis the " regeneration " of the muscle tissue ; and finally because the dystrophic injurious agent is certainly not the lack of vitamin E but something as yet unknown .