tokens: The magnitude of transformation of the microglia assessed by the number of intersections was significantly higher in the PDN groups than in controls in the prefrontal cortex ( moderate - dose , 24 . 1 ; high - dose , 23 . 6 ; controls 18 . 7 ; p < 0 . 01 ) and striatum ( moderate - dose 25 . 6 ; high - dose 26 . 3 ; controls 18 . 9 ; p < 0 . 01 ) , but not in hippocampus .