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Mar 12

From Microbes to Methane: AI-Based Predictive Modeling of Feed Additive Efficacy in Dairy Cows

In an era of increasing pressure to achieve sustainable agriculture, the optimization of livestock feed for enhancing yield and minimizing environmental impact is a paramount objective. This study presents a pioneering approach towards this goal, using rumen microbiome data to predict the efficacy of feed additives in dairy cattle. We collected an extensive dataset that includes methane emissions from 2,190 Holstein cows distributed across 34 distinct sites. The cows were divided into control and experimental groups in a double-blind, unbiased manner, accounting for variables such as age, days in lactation, and average milk yield. The experimental groups were administered one of four leading commercial feed additives: Agolin, Kexxtone, Allimax, and Relyon. Methane emissions were measured individually both before the administration of additives and over a subsequent 12-week period. To develop our predictive model for additive efficacy, rumen microbiome samples were collected from 510 cows from the same herds prior to the study's onset. These samples underwent deep metagenomic shotgun sequencing, yielding an average of 15.7 million reads per sample. Utilizing innovative artificial intelligence techniques we successfully estimated the efficacy of these feed additives across different farms. The model's robustness was further confirmed through validation with independent cohorts, affirming its generalizability and reliability. Our results underscore the transformative capability of using targeted feed additive strategies to both optimize dairy yield and milk composition, and to significantly reduce methane emissions. Specifically, our predictive model demonstrates a scenario where its application could guide the assignment of additives to farms where they are most effective. In doing so, we could achieve an average potential reduction of over 27\% in overall emissions.

PlotQA: Reasoning over Scientific Plots

Existing synthetic datasets (FigureQA, DVQA) for reasoning over plots do not contain variability in data labels, real-valued data, or complex reasoning questions. Consequently, proposed models for these datasets do not fully address the challenge of reasoning over plots. In particular, they assume that the answer comes either from a small fixed size vocabulary or from a bounding box within the image. However, in practice, this is an unrealistic assumption because many questions require reasoning and thus have real-valued answers which appear neither in a small fixed size vocabulary nor in the image. In this work, we aim to bridge this gap between existing datasets and real-world plots. Specifically, we propose PlotQA with 28.9 million question-answer pairs over 224,377 plots on data from real-world sources and questions based on crowd-sourced question templates. Further, 80.76% of the out-of-vocabulary (OOV) questions in PlotQA have answers that are not in a fixed vocabulary. Analysis of existing models on PlotQA reveals that they cannot deal with OOV questions: their overall accuracy on our dataset is in single digits. This is not surprising given that these models were not designed for such questions. As a step towards a more holistic model which can address fixed vocabulary as well as OOV questions, we propose a hybrid approach: Specific questions are answered by choosing the answer from a fixed vocabulary or by extracting it from a predicted bounding box in the plot, while other questions are answered with a table question-answering engine which is fed with a structured table generated by detecting visual elements from the image. On the existing DVQA dataset, our model has an accuracy of 58%, significantly improving on the highest reported accuracy of 46%. On PlotQA, our model has an accuracy of 22.52%, which is significantly better than state of the art models.