Update README.md

README.md

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 short_description: Chat with biological sequences with ChatNT.
 ---
 
-Check out the configuration reference at https://huggingface.co/docs/hub/spaces-config-reference
+# Chat with Biological Sequences with ChatNT
+
+Interact with ChatNT, an AI agent for biological sequences. Upload your FASTA files and ask natural language questions to gain insights and democratize complex biological analysis.
+
+## Key Features:
+
+* **Natural Language Interaction:** Ask questions about your biological sequences in plain English.
+
+* **FASTA File Support:** Easily upload your sequence data.
+
+* **Democratized Access:** Make advanced biological analysis accessible to everyone.
+
+* **Intuitive Interface:** Simple and user-friendly for researchers and enthusiasts alike.
+
+## How to Use:
+
+1. **Upload your FASTA file:** Drag and drop your `.fasta` file into the designated area.
+
+2. **Ask your question:** Type your query in natural language into the chat interface.
+
+3. **Get insights:** Receive immediate, relevant answers about your biological sequences.
+
+## Why This Space?
+
+This demo space provides immediate, free access to ChatNT's capabilities, allowing you to explore the intersection of AI and life sciences without needing specialized hardware or software. It's designed to accelerate discovery, facilitate learning, and inspire innovation within the biological and AI communities.
+
+## About ChatNT:
+
+ChatNT is an AI agent specifically designed to understand and interact with biological sequence data. Its novel approach was recently published in **Nature Machine Intelligence** (find the article here: <https://www.nature.com/articles/s42256-025-01047-1>). It was also featured on the **cover of the June issue of Nature Machine Intelligence** (<https://www.nature.com/natmachintell/>).