jfaustin commited on
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924cdcd
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1 Parent(s): 640e974

add text to explain the correlation tab purpose

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  1. folding_studio_demo/app.py +14 -0
folding_studio_demo/app.py CHANGED
@@ -154,6 +154,20 @@ def model_comparison(api_key: str) -> None:
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  def create_correlation_tab():
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  gr.Markdown("# Correlation with experimental binding affinity data")
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  spr_data_with_scores = pd.read_csv("spr_af_scores_mapped.csv")
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  prettified_columns = {
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  "antibody_name": "Antibody Name",
 
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  def create_correlation_tab():
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  gr.Markdown("# Correlation with experimental binding affinity data")
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+ gr.Markdown("""
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+ This analysis explores the relationship between protein folding model confidence scores and experimental binding affinity data.
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+
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+ The experimental dataset contains binding affinity measurements (KD in nM) between antibody-antigen pairs.
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+ Each data point includes:
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+ - The antibody's light and heavy chain sequences
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+ - The antigen sequence
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+ - The experimental KD value
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+
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+ The analysis involves submitting these sequences to protein folding models for 3D structure prediction.
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+ The models generate various confidence scores for each prediction. These scores are then correlated
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+ with the experimental binding affinity measurements to evaluate their effectiveness as predictors
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+ of binding strength.
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+ """)
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  spr_data_with_scores = pd.read_csv("spr_af_scores_mapped.csv")
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  prettified_columns = {
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  "antibody_name": "Antibody Name",