diff --git "a/dev_JRCT_api/202041213.ipynb" "b/dev_JRCT_api/202041213.ipynb" new file mode 100644--- /dev/null +++ "b/dev_JRCT_api/202041213.ipynb" @@ -0,0 +1,3756 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": 45, + "metadata": {}, + "outputs": [], + "source": [ + "import pandas as pd\n", + "from OpenAITools.JRCTTools import fetch_clinical_trials, extract_jrct_links, create_dataframe_from_urls, reorder_columns" + ] + }, + { + "cell_type": "code", + "execution_count": 46, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "1 ページ目を処理しました。\n", + "2 ページ目を処理しました。\n", + "3 ページ目を処理しました。\n", + "4 ページ目を処理しました。\n", + "5 ページ目を処理しました。\n", + "6 ページ目を処理しました。\n", + "7 ページ目を処理しました。\n", + "8 ページ目を処理しました。\n", + "9 ページ目を処理しました。\n", + "10 ページ目を処理しました。\n", + "11 ページ目を処理しました。\n", + "12 ページ目を処理しました。\n", + "13 ページ目を処理しました。\n", + "14 ページ目を処理しました。\n", + "15 ページ目を処理しました。\n", + "16 ページ目を処理しました。\n", + "17 ページ目を処理しました。\n", + "次のページはありません。全ての結果を取得しました。\n" + ] + } + ], + "source": [ + "# fetch_clinical_trialsを使って検索結果を取得\n", + "results = fetch_clinical_trials(disease_name=\"がん 神経膠腫 骨髄腫 黒色腫 肉腫 間質腫瘍 膠芽腫 内分泌腫瘍 パジェット ラブドイド 癌 固形腫瘍 リンパ腫 中皮腫 新生物 SCLC\", freeword=\"\"\n", + " ,include_not_yet_recruiting=True,\n", + " include_suspended=True,\n", + " specific_clinical_research=True,\n", + " corporate_clinical_trial=True,\n", + " physician_initiated_clinical_trial=True)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# fetch_clinical_trialsを使って検索結果を取得\n", + "results = fetch_clinical_trials(disease_name=\"ラブドイド\", freeword=\"\"\n", + " ,include_not_yet_recruiting=True,\n", + " include_suspended=True,\n", + " specific_clinical_research=True,\n", + " corporate_clinical_trial=True,\n", + " physician_initiated_clinical_trial=True)" + ] + }, + { + "cell_type": "code", + "execution_count": 47, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "832" + ] + }, + "execution_count": 47, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "len(results)" + ] + }, + { + "cell_type": "code", + "execution_count": 48, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Processing URL: https://jrct.niph.go.jp/latest-detail/jRCT2031240552\n", + "Waiting for 15 seconds before the next request...\n", + "Processing URL: https://jrct.niph.go.jp/latest-detail/jRCTs052240215\n", + "Waiting for 15 seconds before the next request...\n", + "Processing URL: https://jrct.niph.go.jp/latest-detail/jRCTs051240214\n", + "Waiting for 15 seconds before the next request...\n", + "Processing URL: https://jrct.niph.go.jp/latest-detail/jRCT2031240547\n", + "Waiting for 15 seconds before the next request...\n", + "Processing URL: https://jrct.niph.go.jp/latest-detail/jRCTs031240545\n", + "Waiting for 15 seconds before the next request...\n", + "Processing URL: https://jrct.niph.go.jp/latest-detail/jRCT2031240542\n", + 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URL研究・治験の目的試験等のフェーズPhase試験の種類Study Type無作為化allocation盲検化masking...中止基準Discontinuation Criteria対象疾患名Health Condition(s) or Problem(s) Studied対象疾患キーワードKeyword介入の内容Intervention(s)JapicCTI NoNCT No
0https://jrct.niph.go.jp/latest-detail/jRCT2031...Treatment1-2NoneNoneNone単一群single arm studyNoneNone...NoneNone以下の進行固形がん患者 ・非小細胞肺癌 ・膵管腺癌 ・結腸・直腸癌Non-Small Cell Lung Cancer (NSCLC) Pancreatic ...AZD0022AZD0022NoneNCT06599502
1https://jrct.niph.go.jp/latest-detail/jRCTs052...結腸癌のロボット支援手術において、クリップ、アドバンスドバイポーラー、ステープラーをロボット...NoneNone介入研究Interventional無作為化比較randomized controlled trialNoneNone...NoneNone結腸癌colon cancerハイブリッドロボット支援手術Hybrid robotic surgeryNoneNone
2https://jrct.niph.go.jp/latest-detail/jRCTs051...エンホルツマブベドチン(EV)に伴う皮膚障害を、好発部位に予防的にステロイド外用薬を塗布する...NoneNone介入研究Interventional無作為化比較randomized controlled trialNoneNone...NoneNone尿路上皮癌Urothelial carcinomaEV標準量投与開始前日夕より28日目まで、1日2回朝夕に試験薬(デルモベート軟膏またはワセリ...The study drug (Delmovate ointment or Vaseline...NoneNone
3https://jrct.niph.go.jp/latest-detail/jRCT2031...フッ化ピリミジン系薬剤に不応または不耐となったFGFR2b陽性の切除不能進行・再発の胃腺癌又...2NoneNoneNone単一群single arm studyNoneNone...NoneNone切除不能進行・再発の胃または食道胃接合部腺癌Advanced Gastric or Gastroesophageal Junction ...・Bemarituzumab (15mg/kg, intravenous, Day1, 15...- Bemarituzumab (15mg/kg, intravenous, Day1, 1...NoneNone
4https://jrct.niph.go.jp/latest-detail/jRCTs031...広範な食道表在癌に対する内視鏡的粘膜下層剥離術(Endoscopic submucosal ...NoneNone介入研究Interventional無作為化比較randomized controlled trialNoneNone...NoneNone広範な食道表在癌Widespread superficial esophageal cancerESD+ステロイド局注療法:一期的にESDを行った直後に、トリアムシノロンアセトニド100 ...Local steroid (triamcinolone acetonide) inject...NoneNone
..................................................................
827https://jrct.niph.go.jp/latest-detail/jRCT2080...NoneNoneNone介入研究InterventionalNoneNoneNoneNone...NoneNoneNoneNoneNoneNoneNoneNoneJapicCTI-184169NCT02609776
828https://jrct.niph.go.jp/latest-detail/jRCTs031...根治切除不能または転移性腎細胞癌に対する抗PD-1抗体(Nivolumab)投与による縮小効...NoneNone介入研究Interventional無作為化比較randomized controlled trialNoneNone...NoneNone根治切除不能または転移性腎細胞癌Unresectable or metastatic renal cell carcinomaArm1:ニボルマブ4週に1回投与を計6コース行う。 Arm2:ニボルマブ4週に1回投与を計...Arm1 Patients receive Nivolumab every 4 weeks ...NoneNone
829https://jrct.niph.go.jp/latest-detail/jRCTs051...鏡視下の食道癌、胃癌、大腸癌手術症例において、リンパ流とリンパ節転移経路の解明、および過不足...NoneNone介入研究Interventional単一群single arm studyNoneNone...NoneNone消化管癌gastroenterological cancer消化管癌gastroenterological cancer癌部周囲粘膜下にIncdocyanine Greenを局注する。Indocyanine Green is injected submucosally aro...NoneNone
830https://jrct.niph.go.jp/latest-detail/jRCT2080...NoneNoneNone介入研究InterventionalNoneNoneNoneNone...NoneNoneNoneNoneNoneNoneNoneNoneJapicCTI-183824None
831https://jrct.niph.go.jp/latest-detail/jRCT2080...NoneNoneNone介入研究InterventionalNoneNoneNoneNone...NoneNoneNoneNoneNoneNoneNoneNoneJapicCTI-152780None
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" + ], + "text/plain": [ + " URL \\\n", + "0 https://jrct.niph.go.jp/latest-detail/jRCT2031... \n", + "1 https://jrct.niph.go.jp/latest-detail/jRCTs052... \n", + "2 https://jrct.niph.go.jp/latest-detail/jRCTs051... \n", + "3 https://jrct.niph.go.jp/latest-detail/jRCT2031... \n", + "4 https://jrct.niph.go.jp/latest-detail/jRCTs031... \n", + ".. ... \n", + "827 https://jrct.niph.go.jp/latest-detail/jRCT2080... \n", + "828 https://jrct.niph.go.jp/latest-detail/jRCTs031... \n", + "829 https://jrct.niph.go.jp/latest-detail/jRCTs051... \n", + "830 https://jrct.niph.go.jp/latest-detail/jRCT2080... \n", + "831 https://jrct.niph.go.jp/latest-detail/jRCT2080... \n", + "\n", + " 研究・治験の目的 試験等のフェーズ Phase 試験の種類 \\\n", + "0 Treatment 1-2 None None \n", + "1 結腸癌のロボット支援手術において、クリップ、アドバンスドバイポーラー、ステープラーをロボット... None None 介入研究 \n", + "2 エンホルツマブベドチン(EV)に伴う皮膚障害を、好発部位に予防的にステロイド外用薬を塗布する... None None 介入研究 \n", + "3 フッ化ピリミジン系薬剤に不応または不耐となったFGFR2b陽性の切除不能進行・再発の胃腺癌又... 2 None None \n", + "4 広範な食道表在癌に対する内視鏡的粘膜下層剥離術(Endoscopic submucosal ... None None 介入研究 \n", + ".. ... ... ... ... \n", + "827 None None None 介入研究 \n", + "828 根治切除不能または転移性腎細胞癌に対する抗PD-1抗体(Nivolumab)投与による縮小効... None None 介入研究 \n", + "829 鏡視下の食道癌、胃癌、大腸癌手術症例において、リンパ流とリンパ節転移経路の解明、および過不足... None None 介入研究 \n", + "830 None None None 介入研究 \n", + "831 None None None 介入研究 \n", + "\n", + " Study Type 無作為化 allocation 盲検化 masking ... \\\n", + "0 None 単一群 single arm study None None ... \n", + "1 Interventional 無作為化比較 randomized controlled trial None None ... \n", + "2 Interventional 無作為化比較 randomized controlled trial None None ... \n", + "3 None 単一群 single arm study None None ... \n", + "4 Interventional 無作為化比較 randomized controlled trial None None ... \n", + ".. ... ... ... ... ... ... \n", + "827 Interventional None None None None ... \n", + "828 Interventional 無作為化比較 randomized controlled trial None None ... \n", + "829 Interventional 単一群 single arm study None None ... \n", + "830 Interventional None None None None ... \n", + "831 Interventional None None None None ... \n", + "\n", + " 中止基準 Discontinuation Criteria 対象疾患名 \\\n", + "0 None None 以下の進行固形がん患者 ・非小細胞肺癌 ・膵管腺癌 ・結腸・直腸癌 \n", + "1 None None 結腸癌 \n", + "2 None None 尿路上皮癌 \n", + "3 None None 切除不能進行・再発の胃または食道胃接合部腺癌 \n", + "4 None None 広範な食道表在癌 \n", + ".. ... ... ... \n", + "827 None None None \n", + "828 None None 根治切除不能または転移性腎細胞癌 \n", + "829 None None 消化管癌 \n", + "830 None None None \n", + "831 None None None \n", + "\n", + " Health Condition(s) or Problem(s) Studied 対象疾患キーワード \\\n", + "0 Non-Small Cell Lung Cancer (NSCLC) Pancreatic ... \n", + "1 colon cancer \n", + "2 Urothelial carcinoma \n", + "3 Advanced Gastric or Gastroesophageal Junction ... \n", + "4 Widespread superficial esophageal cancer \n", + ".. ... ... \n", + "827 None None \n", + "828 Unresectable or metastatic renal cell carcinoma \n", + "829 gastroenterological cancer 消化管癌 \n", + "830 None None \n", + "831 None None \n", + "\n", + " Keyword \\\n", + "0 \n", + "1 \n", + "2 \n", + "3 \n", + "4 \n", + ".. ... \n", + "827 None \n", + "828 \n", + "829 gastroenterological cancer \n", + "830 None \n", + "831 None \n", + "\n", + " 介入の内容 \\\n", + "0 AZD0022 \n", + "1 ハイブリッドロボット支援手術 \n", + "2 EV標準量投与開始前日夕より28日目まで、1日2回朝夕に試験薬(デルモベート軟膏またはワセリ... \n", + "3 ・Bemarituzumab (15mg/kg, intravenous, Day1, 15... \n", + "4 ESD+ステロイド局注療法:一期的にESDを行った直後に、トリアムシノロンアセトニド100 ... \n", + ".. ... \n", + "827 None \n", + "828 Arm1:ニボルマブ4週に1回投与を計6コース行う。 Arm2:ニボルマブ4週に1回投与を計... \n", + "829 癌部周囲粘膜下にIncdocyanine Greenを局注する。 \n", + "830 None \n", + "831 None \n", + "\n", + " Intervention(s) JapicCTI No \\\n", + "0 AZD0022 None \n", + "1 Hybrid robotic surgery None \n", + "2 The study drug (Delmovate ointment or Vaseline... None \n", + "3 - Bemarituzumab (15mg/kg, intravenous, Day1, 1... None \n", + "4 Local steroid (triamcinolone acetonide) inject... None \n", + ".. ... ... \n", + "827 None JapicCTI-184169 \n", + "828 Arm1 Patients receive Nivolumab every 4 weeks ... None \n", + "829 Indocyanine Green is injected submucosally aro... None \n", + "830 None JapicCTI-183824 \n", + "831 None JapicCTI-152780 \n", + "\n", + " NCT No \n", + "0 NCT06599502 \n", + "1 None \n", + "2 None \n", + "3 None \n", + "4 None \n", + ".. ... \n", + "827 NCT02609776 \n", + "828 None \n", + "829 None \n", + "830 None \n", + "831 None \n", + "\n", + "[832 rows x 36 columns]" + ] + }, + "execution_count": 49, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "df" + ] + }, + { + "cell_type": "code", + "execution_count": 58, + "metadata": {}, + "outputs": [], + "source": [ + "# 整列後の DataFrame を作成\n", + "sorted_df = reorder_columns(df)" + ] + }, + { + "cell_type": "code", + "execution_count": 59, + "metadata": {}, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/var/folders/yw/qz00x75d7kb98f7vm8dkhkvw0000gn/T/ipykernel_78020/2717451573.py:1: SettingWithCopyWarning: \n", + "A value is trying to be set on a copy of a slice from a DataFrame.\n", + "Try using .loc[row_indexer,col_indexer] = value instead\n", + "\n", + "See the caveats in the documentation: https://pandas.pydata.org/pandas-docs/stable/user_guide/indexing.html#returning-a-view-versus-a-copy\n", + " sorted_df['JRCT ID'] = [result[0] for result in results]\n", + "/var/folders/yw/qz00x75d7kb98f7vm8dkhkvw0000gn/T/ipykernel_78020/2717451573.py:2: SettingWithCopyWarning: \n", + "A value is trying to be set on a copy of a slice from a DataFrame.\n", + "Try using .loc[row_indexer,col_indexer] = value instead\n", + "\n", + "See the caveats in the documentation: https://pandas.pydata.org/pandas-docs/stable/user_guide/indexing.html#returning-a-view-versus-a-copy\n", + " sorted_df['Title'] = [result[1] for result in results]\n", + "/var/folders/yw/qz00x75d7kb98f7vm8dkhkvw0000gn/T/ipykernel_78020/2717451573.py:3: SettingWithCopyWarning: \n", + "A value is trying to be set on a copy of a slice from a DataFrame.\n", + "Try using .loc[row_indexer,col_indexer] = value instead\n", + "\n", + "See the caveats in the documentation: https://pandas.pydata.org/pandas-docs/stable/user_guide/indexing.html#returning-a-view-versus-a-copy\n", + " sorted_df['TargetJ'] = [result[2] for result in results]\n" + ] + } + ], + "source": [ + "sorted_df['JRCT ID'] = [result[0] for result in results]\n", + "sorted_df['Title'] = [result[1] for result in results]\n", + "sorted_df['TargetJ'] = [result[2] for result in results]" + ] + }, + { + "cell_type": "code", + "execution_count": 60, + "metadata": {}, + "outputs": [], + "source": [ + "#new_order = [\"JRCT ID\", 'NCT No', 'JapicCTI No',\"Title\",'Target','対象疾患名','Health Condition(s) or Problem(s) Studied'] + [col for col in sorted_df.columns if col not in [\"JRCT ID\", 'NCT No', 'JapicCTI No',\"Title\",'Target','対象疾患名','Health Condition(s) or Problem(s) Studied']]\n", + "new_order = [\"JRCT ID\", 'NCT No', 'JapicCTI No',\"Title\",'TargetJ','対象疾患名','Health Condition(s) or Problem(s) Studied'] + [col for col in sorted_df.columns if col not in [\"JRCT ID\", 'NCT No', 'JapicCTI No',\"Title\",'TargetJ','対象疾患名','Health Condition(s) or Problem(s) Studied']]" + ] + }, + { + "cell_type": "code", + "execution_count": 61, + "metadata": {}, + "outputs": [], + "source": [ + "sorted_df = sorted_df[new_order]\n", + "sorted_df.rename(columns={\n", + " '対象疾患名': 'Target',\n", + " 'Health Condition(s) or Problem(s) Studied': 'TargetEnglish'\n", + "},inplace=True)\n" + ] + }, + { + "cell_type": "code", + "execution_count": 63, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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JRCT IDNCT NoJapicCTI NoTitleTargetJTargetTargetEnglish研究・治験の目的試験等のフェーズ試験の種類...assignmentpurposeInclusion CriteriaExclusion CriteriaAge MinimumAge MaximumGenderDiscontinuation CriteriaKeywordIntervention(s)
0jRCT2031240552NCT06599502NoneKRAS G12D 変異陽性がん患者を対象としてAZD0022 の単剤療法及び抗がん剤との併...以下の進行固形がん患者\\n・非小細胞肺癌\\n・膵管腺癌\\n・結腸・直腸癌以下の進行固形がん患者 ・非小細胞肺癌 ・膵管腺癌 ・結腸・直腸癌Non-Small Cell Lung Cancer (NSCLC) Pancreatic ...Treatment1-2None...single assignmenttreatment purpose1. Participant must be 18 years or more, or th...1. Any significant laboratory finding or any s...18age old overNo limitBothNoneAZD0022
1jRCTs052240215NoneNoneロボット支援結腸癌手術における腹腔鏡デバイスを用いたハイブリッドロボット支援手術の有効性を検...結腸癌結腸癌colon cancer結腸癌のロボット支援手術において、クリップ、アドバンスドバイポーラー、ステープラーをロボット...None介入研究...parallel assignmenttreatment purpose1. Patients whose age at registration is 18 ye...1. Patients planning combined resection of oth...18age old overNo limitBothNoneHybrid robotic surgery
2jRCTs051240214NoneNoneエンホルツマブベドチンに伴う皮膚障害に対する予防的ステロイド外用薬投与の有効性に関する多施設...尿路上皮癌尿路上皮癌Urothelial carcinomaエンホルツマブベドチン(EV)に伴う皮膚障害を、好発部位に予防的にステロイド外用薬を塗布する...None介入研究...parallel assignmentprevention purposeMale and female patients receiving EV at the s...1. Patients with a history of EV administratio...18age old overNo limitBothNoneThe study drug (Delmovate ointment or Vaseline...
3jRCT2031240547NoneNoneFGFR2b陽性切除不能進行・再発の胃または食道胃接合部腺癌を対象としたBemarituzu...切除不能進行・再発の胃または食道胃接合部腺癌切除不能進行・再発の胃または食道胃接合部腺癌Advanced Gastric or Gastroesophageal Junction ...フッ化ピリミジン系薬剤に不応または不耐となったFGFR2b陽性の切除不能進行・再発の胃腺癌又...2None...single assignmenttreatment purpose1) Histologically documented gastric or GEJ ad...1) Prior treatment with taxanes 2) Prior treat...18age old overNo limitBothNone- Bemarituzumab (15mg/kg, intravenous, Day1, 1...
4jRCTs031240545NoneNoneJCOG2315: 広範な食道表在癌に対する内視鏡的粘膜下層剥離術後の狭窄予防を目的とするス...広範な食道表在癌広範な食道表在癌Widespread superficial esophageal cancer広範な食道表在癌に対する内視鏡的粘膜下層剥離術(Endoscopic submucosal ...None介入研究...parallel assignmentprevention purpose1st inclusion criteria (1) Meet either of the ...(1) Synchronous or metachronous (within 1 year...18age old over85age old underBothNoneLocal steroid (triamcinolone acetonide) inject...
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827jRCT2080224108NCT02609776JapicCTI-184169進行性非小細胞肺癌患者を対象としてヒト二重特異性抗EGFR 及びcMet 抗体のJNJ-61...非小細胞性肺癌NoneNoneNoneNone介入研究...NoneNoneNoneNoneNoneNoneNoneNoneNoneNone
828jRCTs031180024NoneNone根治切除不能または転移性腎細胞癌に対するNivolumab併用画像誘導3次元集光式超寡分割照...根治切除不能または転移性腎細胞癌根治切除不能または転移性腎細胞癌Unresectable or metastatic renal cell carcinoma根治切除不能または転移性腎細胞癌に対する抗PD-1抗体(Nivolumab)投与による縮小効...None介入研究...parallel assignmenttreatment purposePrimary registration 1)Cytologically or histol...Primary regisration 1)Active double cancer(exc...20age old overNo limitBothNoneArm1 Patients receive Nivolumab every 4 weeks ...
829jRCTs051180001NoneNone消化器癌に対する術中ICG局注赤外線内視鏡観察による術中リンパ節、リンパ流評価の有用性につい...消化管癌消化管癌gastroenterological cancer鏡視下の食道癌、胃癌、大腸癌手術症例において、リンパ流とリンパ節転移経路の解明、および過不足...None介入研究...single assignmentdiagnostic purposePatients with the diagnosis of esophageal or g...Patients who refused to join in this study. Pa...20age old over100age old underBothNonegastroenterological cancerIndocyanine Green is injected submucosally aro...
830jRCT2080223768NoneJapicCTI-183824固形癌患者を対象としたTAS0313の第I/II相試験固形癌（尿路上皮癌など）NoneNoneNoneNone介入研究...NoneNoneNoneNoneNoneNoneNoneNoneNoneNone
831jRCT2080222728NoneJapicCTI-152780進行固形がん患者を対象にTAS-117の安全性，忍容性，薬物動態及び有効性を検討する非盲検，...固形がん患者，卵巣明細胞癌患者，子宮内膜癌患者NoneNoneNoneNone介入研究...NoneNoneNoneNoneNoneNoneNoneNoneNoneNone
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832 rows × 39 columns

\n", + "
" + ], + "text/plain": [ + " JRCT ID NCT No JapicCTI No \\\n", + "0 jRCT2031240552 NCT06599502 None \n", + "1 jRCTs052240215 None None \n", + "2 jRCTs051240214 None None \n", + "3 jRCT2031240547 None None \n", + "4 jRCTs031240545 None None \n", + ".. ... ... ... \n", + "827 jRCT2080224108 NCT02609776 JapicCTI-184169 \n", + "828 jRCTs031180024 None None \n", + "829 jRCTs051180001 None None \n", + "830 jRCT2080223768 None JapicCTI-183824 \n", + "831 jRCT2080222728 None JapicCTI-152780 \n", + "\n", + " Title \\\n", + "0 KRAS G12D 変異陽性がん患者を対象としてAZD0022 の単剤療法及び抗がん剤との併... \n", + "1 ロボット支援結腸癌手術における腹腔鏡デバイスを用いたハイブリッドロボット支援手術の有効性を検... \n", + "2 エンホルツマブベドチンに伴う皮膚障害に対する予防的ステロイド外用薬投与の有効性に関する多施設... \n", + "3 FGFR2b陽性切除不能進行・再発の胃または食道胃接合��腺癌を対象としたBemarituzu... \n", + "4 JCOG2315: 広範な食道表在癌に対する内視鏡的粘膜下層剥離術後の狭窄予防を目的とするス... \n", + ".. ... \n", + "827 進行性非小細胞肺癌患者を対象としてヒト二重特異性抗EGFR 及びcMet 抗体のJNJ-61... \n", + "828 根治切除不能または転移性腎細胞癌に対するNivolumab併用画像誘導3次元集光式超寡分割照... \n", + "829 消化器癌に対する術中ICG局注赤外線内視鏡観察による術中リンパ節、リンパ流評価の有用性につい... \n", + "830 固形癌患者を対象としたTAS0313の第I/II相試験 \n", + "831 進行固形がん患者を対象にTAS-117の安全性，忍容性，薬物動態及び有効性を検討する非盲検，... \n", + "\n", + " TargetJ Target \\\n", + "0 以下の進行固形がん患者\\n・非小細胞肺癌\\n・膵管腺癌\\n・結腸・直腸癌 以下の進行固形がん患者 ・非小細胞肺癌 ・膵管腺癌 ・結腸・直腸癌 \n", + "1 結腸癌 結腸癌 \n", + "2 尿路上皮癌 尿路上皮癌 \n", + "3 切除不能進行・再発の胃または食道胃接合部腺癌 切除不能進行・再発の胃または食道胃接合部腺癌 \n", + "4 広範な食道表在癌 広範な食道表在癌 \n", + ".. ... ... \n", + "827 非小細胞性肺癌 None \n", + "828 根治切除不能または転移性腎細胞癌 根治切除不能または転移性腎細胞癌 \n", + "829 消化管癌 消化管癌 \n", + "830 固形癌（尿路上皮癌など） None \n", + "831 固形がん患者，卵巣明細胞癌患者，子宮内膜癌患者 None \n", + "\n", + " TargetEnglish \\\n", + "0 Non-Small Cell Lung Cancer (NSCLC) Pancreatic ... \n", + "1 colon cancer \n", + "2 Urothelial carcinoma \n", + "3 Advanced Gastric or Gastroesophageal Junction ... \n", + "4 Widespread superficial esophageal cancer \n", + ".. ... \n", + "827 None \n", + "828 Unresectable or metastatic renal cell carcinoma \n", + "829 gastroenterological cancer \n", + "830 None \n", + "831 None \n", + "\n", + " 研究・治験の目的 試験等のフェーズ 試験の種類 ... \\\n", + "0 Treatment 1-2 None ... \n", + "1 結腸癌のロボット支援手術において、クリップ、アドバンスドバイポーラー、ステープラーをロボット... None 介入研究 ... \n", + "2 エンホルツマブベドチン(EV)に伴う皮膚障害を、好発部位に予防的にステロイド外用薬を塗布する... None 介入研究 ... \n", + "3 フッ化ピリミジン系薬剤に不応または不耐となったFGFR2b陽性の切除不能進行・再発の胃腺癌又... 2 None ... \n", + "4 広範な食道表在癌に対する内視鏡的粘膜下層剥離術(Endoscopic submucosal ... None 介入研究 ... \n", + ".. ... ... ... ... \n", + "827 None None 介入研究 ... \n", + "828 根治切除不能または転移性腎細胞癌に対する抗PD-1抗体(Nivolumab)投与による縮小効... None 介入研究 ... \n", + "829 鏡視下の食道癌、胃癌、大腸癌手術症例において、リンパ流とリンパ節転移経路の解明、および過不足... None 介入研究 ... \n", + "830 None None 介入研究 ... \n", + "831 None None 介入研究 ... \n", + "\n", + " assignment purpose \\\n", + "0 single assignment treatment purpose \n", + "1 parallel assignment treatment purpose \n", + "2 parallel assignment prevention purpose \n", + "3 single assignment treatment purpose \n", + "4 parallel assignment prevention purpose \n", + ".. ... ... \n", + "827 None None \n", + "828 parallel assignment treatment purpose \n", + "829 single assignment diagnostic purpose \n", + "830 None None \n", + "831 None None \n", + "\n", + " Inclusion Criteria \\\n", + "0 1. Participant must be 18 years or more, or th... \n", + "1 1. Patients whose age at registration is 18 ye... \n", + "2 Male and female patients receiving EV at the s... \n", + "3 1) Histologically documented gastric or GEJ ad... \n", + "4 1st inclusion criteria (1) Meet either of the ... \n", + ".. ... \n", + "827 None \n", + "828 Primary registration 1)Cytologically or histol... \n", + "829 Patients with the diagnosis of esophageal or g... \n", + "830 None \n", + "831 None \n", + "\n", + " Exclusion Criteria Age Minimum \\\n", + "0 1. Any significant laboratory finding or any s... 18age old over \n", + "1 1. Patients planning combined resection of oth... 18age old over \n", + "2 1. Patients with a history of EV administratio... 18age old over \n", + "3 1) Prior treatment with taxanes 2) Prior treat... 18age old over \n", + "4 (1) Synchronous or metachronous (within 1 year... 18age old over \n", + ".. ... ... \n", + "827 None None \n", + "828 Primary regisration 1)Active double cancer(exc... 20age old over \n", + "829 Patients who refused to join in this study. Pa... 20age old over \n", + "830 None None \n", + "831 None None \n", + "\n", + " Age Maximum Gender Discontinuation Criteria \\\n", + "0 No limit Both None \n", + "1 No limit Both None \n", + "2 No limit Both None \n", + "3 No limit Both None \n", + "4 85age old under Both None \n", + ".. ... ... ... \n", + "827 None None None \n", + "828 No limit Both None \n", + "829 100age old under Both None \n", + "830 None None None \n", + "831 None None None \n", + "\n", + " Keyword \\\n", + "0 \n", + "1 \n", + "2 \n", + "3 \n", + "4 \n", + ".. ... \n", + "827 None \n", + "828 \n", + "829 gastroenterological cancer \n", + "830 None \n", + "831 None \n", + "\n", + " Intervention(s) \n", + "0 AZD0022 \n", + "1 Hybrid robotic surgery \n", + "2 The study drug (Delmovate ointment or Vaseline... \n", + "3 - Bemarituzumab (15mg/kg, intravenous, Day1, 1... \n", + "4 Local steroid (triamcinolone acetonide) inject... \n", + ".. ... \n", + "827 None \n", + "828 Arm1 Patients receive Nivolumab every 4 weeks ... \n", + "829 Indocyanine Green is injected submucosally aro... \n", + "830 None \n", + "831 None \n", + "\n", + "[832 rows x 39 columns]" + ] + }, + "execution_count": 63, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "sorted_df" + ] + }, + { + "cell_type": "code", + "execution_count": 64, + "metadata": {}, + "outputs": [], + "source": [ + "sorted_df.to_csv('../JRCT20241215Cancer.csv')" + ] + }, + { + "cell_type": "code", + "execution_count": 65, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "array(['NCT06599502', None, 'NCT06003231', 'NCT06632951', 'NCT06692738',\n", + " 'NCT06573294', 'NCT06627647', 'NCT06549595', 'NCT06660654',\n", + " 'NCT06496178', 'NCT06608927', 'NCT04898634', 'NCT06393374',\n", + " 'NCT06312176', 'NCT06629779', 'NCT06698042', 'NCT06561386',\n", + " 'NCT05445778', 'NCT06641908', 'NCT06509906', 'NCT06598306',\n", + " 'NCT06486441', 'NCT05605899', 'NCT06435429', 'NCT06586515',\n", + " 'NCT06077760', 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