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Create ncbi.py

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  1. mcp/ncbi.py +35 -0
mcp/ncbi.py ADDED
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+ # mcp/ncbi.py
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+ """
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+ NCBI E-utilities helpers – Gene, Protein, ClinVar, MeSH.
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+ """
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+
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+ import os
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+ import httpx
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+ from typing import List, Dict
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+
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+ NCBI_KEY = os.getenv("BIO_KEY") # optional but increases rate limits
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+ BASE = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/"
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+
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+ async def _get(endpoint: str, params: Dict) -> Dict:
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+ if NCBI_KEY:
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+ params["api_key"] = NCBI_KEY
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+ async with httpx.AsyncClient(timeout=20) as client:
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+ r = await client.get(f"{BASE}{endpoint}", params=params)
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+ r.raise_for_status()
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+ return r.json() if r.headers["Content-Type"].startswith("application/json") else r.text
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+
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+ # ---------- Public helpers ----------
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+ async def search_gene(term: str, retmax: int = 5) -> List[Dict]:
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+ """Return basic gene info (ID + name/symbol) by search term."""
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+ data = await _get("esearch.fcgi", {"db": "gene", "term": term, "retmode": "json", "retmax": retmax})
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+ ids = data["esearchresult"]["idlist"]
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+ if not ids:
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+ return []
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+ summary = await _get("esummary.fcgi", {"db": "gene", "id": ",".join(ids), "retmode": "json"})
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+ return list(summary["result"].values())[1:] # first key is 'uids'
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+
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+ async def get_mesh_definition(term: str) -> str:
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+ """Return MeSH term definition (first record)."""
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+ text = await _get("esummary.fcgi", {"db": "mesh", "term": term, "retmode": "json", "retmax": 1})
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+ recs = list(text["result"].values())[1:]
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+ return recs[0].get("ds_meshterms", [""])[0] if recs else ""