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# Systems Chemical Biology of Infection and Resistance Laboratory

<img src="https://cdn-uploads.huggingface.co/production/uploads/6572ef05cba827dcf8318dad/vdCkUb1iGQJKh3hEts8x3.png" alt="Logo of SCBIR lab" width="300">

The SCBIR lab is based the [Francis Crick Institute](https://crick.ac.uk) in London. We use large-scale genetics and chemical biology to study 
how pathogenic bacteria infect and evolve resistance to antibiotics.

Ultimately, we aim to enable antimicrobial therapies which exploit key weaknesses in the ability of pathogenic bacteria to infect and evolve resistance to antibiotics.

Our work focuses on these areas (click the links for more information):

- [Accelerating discovery of new small molecules with new targets](https://www.scbir.org/research.html#accelerating-discovery-of-new-small-molecules-with-new-targets)
    - [Rapid target annotation](https://www.scbir.org/research.html#rapid-target-annotation)
    - [Optimising chemical library design](https://www.scbir.org/research.html#optimising-chemical-library-design)
- [Defining targets for bacterial survival and infection](https://www.scbir.org/research.html#defining-targets-for-bacterial-survival-and-infection)

Find out more about our research [here](https://scbir.org)!