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In chemistry, an enantiomer (/ɪˈnænti.əmər, ɛ-, -oʊ-/ ih-NAN-tee-ə-mər; from Ancient Greek ἐναντίος (enantíos) opposite, and μέρος (méros) part) – also called optical isomer, antipode, or optical antipode – is one of two stereoisomers that are nonsuperposable onto their own mirror image. Enantiomers are much like one's right and left hands; without mirroring one of them, hands cannot be superposed onto each other. No amount of reorientation in three spatial dimensions will allow the four unique groups on the chiral carbon (see chirality) to line up exactly. The number of stereoisomers a molecule has can be determined by the number of chiral carbons it has.
A molecule with chirality rotates plane-polarized light. A mixture of equal amounts of each enantiomer, a racemic mixture or a racemate, does not rotate light.
Stereoisomers include both enantiomers and diastereomers. Diastereomers, like enantiomers, share the same molecular formula and are also nonsuperposable onto each other; however, they are not mirror images of each other. | 0 | Theoretical and Fundamental Chemistry |
The process of detonation spraying was first developed in 1955 by H.B. Sargent, R.M. Poorman and H. Lamprey and was subsequently patented. It was first made commercially available as the D-Gun Process by Union Carbide in the same year. It was further developed in the 1960s by the Paton Institute in Kiev (Ukraine), into a technology that is still currently commercially available in the US by Demeton Technologies (West Babylon). | 1 | Applied and Interdisciplinary Chemistry |
;BLOSUM: Blocks Substitution Matrix, a substitution matrix used for sequence alignment of proteins.
;Scoring metrics (statistical versus biological): When evaluating a sequence alignment, one would like to know how meaningful it is. This requires a scoring matrix, or a table of values that describes the probability of a biologically meaningful amino-acid or nucleotide residue-pair occurring in an alignment. Scores for each position are obtained frequencies of substitutions in blocks of local alignments of protein sequences.
;BLOSUM r:
:The matrix built from blocks with less than r% of similarity
:* E.g., BLOSUM62 is the matrix built using sequences with less than 62% similarity (sequences with ≥ 62% identity were clustered)
:* Note: BLOSUM 62 is the default matrix for protein BLAST. Experimentation has shown that the BLOSUM-62 matrix is among the best for detecting most weak protein similarities.
Several sets of BLOSUM matrices exist using different alignment databases, named with numbers. BLOSUM matrices with high numbers are designed for comparing closely related sequences, while those with low numbers are designed for comparing distant related sequences. For example, BLOSUM80 is used for closely related alignments, and BLOSUM45 is used for more distantly related alignments. The matrices were created by merging (clustering) all sequences that were more similar than a given percentage into one single sequence and then comparing those sequences (that were all more divergent than the given percentage value) only; thus reducing the contribution of closely related sequences. The percentage used was appended to the name, giving BLOSUM80 for example where sequences that were more than 80% identical were clustered. | 1 | Applied and Interdisciplinary Chemistry |
PED possesses many advantageous attributes that make it well suited to investigating crystal structures via direct methods approaches:
# Quasi-kinematical diffraction patterns: While the underlying physics of the electron diffraction is still dynamical in nature, the conditions used to collect PED patterns minimize many of these effects. The scan/de-scan procedure reduces ion channeling because the pattern is generated off of the zone axis. Integration via precession of the beam minimizes the effect of non-systematic inelastic scattering, such as Kikuchi lines. Few reflections are strongly excited at any moment during precession, and those that are excited are generally much closer to a two-beam condition (dynamically coupled only to the forward-scattered beam). Furthermore, for large precession angles, the radius of the excited Laue circle becomes quite large. These contributions combine such that the overall integrated diffraction pattern resembles the kinematical pattern much more closely than a single zone axis pattern.
# Broader range of measured reflections: The Laue circle (see Ewald sphere) that is excited at any given moment during precession extends farther into reciprocal space. After integration over multiple precessions, many more reflections in the zeroeth order Laue zone (ZOLZ) are present, and as stated previously, their relative intensities are much more kinematical. This provides considerably more information to input into direct methods calculations, improving the accuracy of phase determination algorithms. Similarly, more higher order Laue zone (HOLZ) reflections are present in the pattern, which can provide more complete information about the three-dimensional nature of reciprocal space, even in a single two-dimensional PED pattern.
# Practical robustness: PED is less sensitive to small experimental variations than other electron diffraction techniques. Since the measurement is an average over many incident beam directions, the pattern is less sensitive to slight misorientation of the zone axis from the optic axis of the microscope, and resulting PED patterns will generally still display the zone axis symmetry. The patterns obtained are also less sensitive to the thickness of the sample, a parameter with strong influence in standard electron diffraction patterns.
# Very small probe size: Because x-rays interact so weakly with matter, there is a minimum size limit of approximately 5 µm for single crystals that can be examined via x-ray diffraction methods. In contrast, electrons can be used to probe much smaller nano-crystals in a TEM. In PED, the probe size is limited by the lens aberrations and sample thickness. With a typical value for spherical aberration, the minimum probe size is usually around 50 nm. However, with Cs corrected microscopes, the probe can be made much smaller. | 0 | Theoretical and Fundamental Chemistry |
While plastics based on organic materials were manufactured by chemical companies throughout the 20th century, the first company solely focused on bioplastics—Marlborough Biopolymers—was founded in 1983. However, Marlborough and other ventures that followed failed to find commercial success, with the first such company to secure long-term financial success being the Italian company Novamont, founded in 1989.
Bioplastics remain less than one percent of all plastics manufactured worldwide. Most bioplastics do not yet save more carbon emissions than are required to manufacture them. It is estimated that replacing 250 million tons of the plastic manufactured each year with bio-based plastics would require 100 million hectares of land, or 7 percent of the arable land on Earth. And when bioplastics reach the end of their life cycle, those designed to be compostable and marketed as biodegradable are often sent to landfills due to the lack of proper composting facilities or waste sorting, where they then release methane as they break down anaerobically.
COPA (Committee of Agricultural Organisation in the European Union) and COGEGA (General Committee for the Agricultural Cooperation in the European Union) have made an assessment of the potential of bioplastics in different sectors of the European economy: | 0 | Theoretical and Fundamental Chemistry |
Following Albrecht Kossel's original proposal in 1891, natural products are often divided into two major classes, the primary and secondary metabolites. Primary metabolites have an intrinsic function that is essential to the survival of the organism that produces them. Secondary metabolites in contrast have an extrinsic function that mainly affects other organisms. Secondary metabolites are not essential to survival but do increase the competitiveness of the organism within its environment. Because of their ability to modulate biochemical and signal transduction pathways, some secondary metabolites have useful medicinal properties.
Natural products especially within the field of organic chemistry are often defined as primary and secondary metabolites. A more restrictive definition limiting natural products to secondary metabolites is commonly used within the fields of medicinal chemistry and pharmacognosy. | 1 | Applied and Interdisciplinary Chemistry |
A comparison between a pulsed and non-pulsed dc current electrolysers was explored in 1993 by Shaaban, that demonstrated a non-pulsed current used the least electrical power. This opposes the previous and future works conducted.
The experimental electrolyser separated the anolyte and catholyte compartments and used a 324-Naflon membrane to allow the ion exchange. The distance between the anode, made with platinum coated titanium, and the cathode, stainless steel, was 3mm and was immersed in a 10 weight percent sulfuric acid electrolyte. He conducted tests under several different frequencies that included 0.01 Hz, 0.5 kHz, 5 kHz, i kHz, 10 kHz, 25 kHz, and 40 kHz and with four duty cycles, 10, 25, 50, and 80%.
Initial observations revealed that the off-period resulted in a reversal in polarity, causing the reaction to reverse. This effected the cathode, which displayed a 2g loss after experimentation. A diode was input into the circuit to rectify the polarity. However, the cell was prevented from dropping to 0 V during the off-period, maintaining a higher value of 2.3V. This further impacted the experiment, distorting the square wave produced by the function generator Shaaban used, as the electrical potential provided needed to overcome the cell voltage of 2.3V before current could flow. Bokris et al. records that current would continue to flow, discharging ions from the EDL, but this was contradicted in this experiment. This only occurred when the diode was in place but it prevented a current spike in the duty cycle as well.
With a 10% duty cycle at a 1 kHz pulse, temperature increases of nearly 7 °C greater than in the non-pulsed experimental electrolysis, were found. Temperature increases can prevent the circuit
Calculating the power consumption, it was determined a non-pulsed current had power demand losses of 3.5%, and a pulsed current resulted in 13 - 16% losses. It also opposes the idea from Bockris et al. that the effectiveness of non-pulsed dc current electrolysis increases by a factor of 2 when a pulsed current is applied. | 0 | Theoretical and Fundamental Chemistry |
Andreas Hierlemann (17 August 1964) is a German chemist and professor of Biosystems Engineering at ETH Zurich. He is known for his work in the field of CMOS-based chemical and biomicrosensors and high-density microelectrode arrays. | 0 | Theoretical and Fundamental Chemistry |
The PubChem links gives access to more information on the compounds, including other names, ids, toxicity and safety. | 0 | Theoretical and Fundamental Chemistry |
Hydroacylation is a type of organic reaction in which an electron-rich unsaturated hydrocarbon inserts into a formyl C-H bond. With alkenes, the product is a ketone:
:RCHO + CH=CHR → RC(O)CHCHR
With an alkyne instead, the reaction produces an α,β-unsaturated ketone.
The reaction requires a metal catalyst or a radical initiator. It is almost invariably practiced as an intramolecular reaction using homogeneous catalysts, often based on rhodium phosphines. | 0 | Theoretical and Fundamental Chemistry |
Dixanthogen disulfides are a class of organosulfur compounds with the formula . Usually yellow solids, they are the product of the oxidation of xanthate salts. A common derivative is diethyl dixanthogen disulfide. Diisopropyl dixanthogen disulfide is commercially available. They are structurally related to thiuram disulfides. | 0 | Theoretical and Fundamental Chemistry |
Uranium oxides react with fluorine to form gaseous uranium hexafluoride, most of the plutonium reacts to form gaseous plutonium hexafluoride, a majority of fission products (especially electropositive elements: lanthanides, strontium, barium, yttrium, caesium) form nonvolatile fluorides. Few metals in the fission products (the transition metals niobium, ruthenium, technetium, molybdenum, and the halogen iodine) form volatile (boiling point <200 °C) fluorides that accompany the uranium and plutonium hexafluorides, together with inert gases. Distillation is then used to separate the uranium hexafluoride from the mixture.
The nonvolatile alkaline fission products and minor actinides is most suitable for further processing with dry electrochemical processing (pyrochemical) non-aqueous methods. The lanthanide fluorides are difficult to dissolve in the nitric acid used for aqueous reprocessing methods, such as PUREX, DIAMEX and SANEX, which use solvent extraction. Fluoride volatility is only one of several pyrochemical processes designed to reprocess used nuclear fuel.
The [https://archive.today/20070609212936/http://www.nri.cz/eng/index.html Řež nuclear research institute] at Řež in the Czech Republic tested screw dosers that fed ground uranium oxide (simulating used fuel pellets) into a fluorinator where the particles were burned in fluorine gas to form uranium hexafluoride.
Hitachi has developed a technology, called FLUOREX, which combines fluoride volatility, to extract uranium, with more traditional solvent extraction (PUREX), to extract plutonium and other transuranics]. The FLUOREX-based fuel cycle is intended for use with the Reduced moderation water reactor. | 0 | Theoretical and Fundamental Chemistry |
A single, broad singlet is observed at 3.2 ppm at room temperature in the solution state phosphorus nuclear magnetic resonance (PNMR) of ((Dipp)P)Ge. This signal is consistent with rapid exchange between the planar and pyramidal phosphorus centers. As the temperature is reduced to -80 C, the signal becomes two broad, equal intensity singlets at -42.0 ppm and 8.0.
Two peaks with isotropic chemical shifts of 81.9 and -61.6 ppm, in a 1:1 ratio are observed in the solid state PNMR. No other signals are observed in the PNMR. In general diphosphagermylenes with pyramidal phosphorus centers exhibit a chemical shift close to those of free phosphine. In addition, planar phosphorus centers of Ge=P compounds generally have a downfield PNMR shift. Consequently, peaks at 81.9 and -61.6 ppm have been assigned as planar and pyramidal phosphorus centers of ((Dipp)P)Ge, respectively. This has been supported by DFT calculations that predict PNMR shifts of planar and pyramidal phosphorus centers of ((Dipp)P)Ge are at 100 and -61 ppm. | 0 | Theoretical and Fundamental Chemistry |
Suspensions of nanoparticles are possible since the interaction of the particle surface with the solvent is strong enough to overcome density differences, which otherwise usually result in a material either sinking or floating in a liquid. | 0 | Theoretical and Fundamental Chemistry |
The common name for an aldehyde is derived from the common name of the corresponding carboxylic acid by dropping the word acid and changing the suffix from -ic or -oic to -aldehyde.
*Formaldehyde
*Acetaldehyde | 0 | Theoretical and Fundamental Chemistry |
Sucrose esters are used as food additives in a variety of food. European Parliament and Council Directive No 95/2/EC limited the use of sucrose esters under E 473 in each kind of food. No longer in force, Date of end of validity: 20/01/2010; Repealed by [https://eur-lex.europa.eu/legal-content/en/TXT/?uri=CELEX:32008R1333 32008R1333] . | 0 | Theoretical and Fundamental Chemistry |
Agmatine hypoglycemic effects are the result of simultaneous modulation of several molecular mechanisms involved in blood glucose regulation. | 1 | Applied and Interdisciplinary Chemistry |
Conventional deuteron fusion is a two-step process, in which an unstable high-energy intermediary is formed:
:H + H → HeNuclear isomer| + 24 MeV
Experiments have shown only three decay pathways for this excited-state nucleus, with the branching ratio showing the probability that any given intermediate follows a particular pathway. The products formed via these decay pathways are:
:He → n + He + 3.3 MeV (ratio=50%)
:He → p + H + 4.0 MeV (ratio=50%)
:He → He + γ + 24 MeV (ratio=10)
Only about one in a million of the intermediaries take the third pathway, making its products very rare compared to the other paths. This result is consistent with the predictions of the Bohr model. If 1 watt (6.242 × 10 eV/s) were produced from ~2.2575 × 10 deuteron fusions per second, with the known branching ratios, the resulting neutrons and tritium (H) would be easily measured. Some researchers reported detecting He but without the expected neutron or tritium production; such a result would require branching ratios strongly favouring the third pathway, with the actual rates of the first two pathways lower by at least five orders of magnitude than observations from other experiments, directly contradicting both theoretically predicted and observed branching probabilities. Those reports of He production did not include detection of gamma rays, which would require the third pathway to have been changed somehow so that gamma rays are no longer emitted.
The known rate of the decay process together with the inter-atomic spacing in a metallic crystal makes heat transfer of the 24 MeV excess energy into the host metal lattice prior to the intermediary's decay inexplicable by conventional understandings of momentum and energy transfer, and even then there would be measurable levels of radiation. Also, experiments indicate that the ratios of deuterium fusion remain constant at different energies. In general, pressure and chemical environment cause only small changes to fusion ratios. An early explanation invoked the Oppenheimer–Phillips process at low energies, but its magnitude was too small to explain the altered ratios. | 0 | Theoretical and Fundamental Chemistry |
The nephelauxetic effect is a term used in the inorganic chemistry of transition metals. It refers to a decrease in the Racah interelectronic repulsion parameter, given the symbol B, that occurs when a transition-metal free ion forms a complex with ligands. The name "nephelauxetic" comes from the Greek for cloud-expanding and was proposed by the Danish inorganic chemist C. K. Jorgensen. The presence of this effect highlights the disadvantages of crystal field theory, which treats metal-ligand interactions as purely electrostatic, since the nephelauxetic effect reveals the covalent character in the metal-ligand interaction. | 0 | Theoretical and Fundamental Chemistry |
Aptamers were originally discovered in 1990 when Lary Gold and Craig Tuerk utilized a method of directed evolution known as SELEX to isolate a small single stranded RNA molecule that was capable of binding to T4 bacteriophage DNA polymerase. Additionally, the term “aptamer” was coined by Andrew Ellington, who worked with Jack Szostak to select an RNA aptamer that was capable of tight binding to certain organic dye molecules. The term itself is a conglomeration of the Latin “aptus” or “to fit” and the Greek “meros” or “part."
RNA aptamers are not so much “created” as “selected.” To develop an RNA aptamer capable of selective binding to a molecular target, a method known as Systematic Evolution of Ligands by EXponential Enrichment (SELEX) is used to isolate a unique RNA aptamer from a pool of ~10^13 to 10^16 different aptamers, otherwise known as a library. The library of potential aptamer oligonucleotides is then incubated with a non-target species so as to remove aptamers that exhibit non-specific binding. After subsequent removal of the non-specific aptamers, the remaining library members are then exposed to the desired target, which can be a protein, peptide, cell type, or even an organ (in the case of live animal-based SELEX). From there, the RNA aptamers which were bound to the target are transcribed to cDNA which then is amplified through PCR, and the PCR products are then re-transcribed to RNA. These new RNA transcripts are then used to repeat the selection cycle many times, thus eventually producing a homogeneous pool of RNA aptamers capable of highly specific, high-affinity target binding. | 1 | Applied and Interdisciplinary Chemistry |
When metabolites from the TCA cycle or glutamate are used as a precursor for glyceroneogenesis, the regulator in the TCA cycle can also cause fluctuations in the levels of products formed by glyceroneogenesis. Regulation of the TCA cycle is mainly determined by product inhibition and substrate availability. The TCA cycle will slow down when the environment contains excess product, or deficiency of the substrate such as ADP and NAD+. | 1 | Applied and Interdisciplinary Chemistry |
Gram-positive bacteria use autoinducing peptides (AIP) as their autoinducers.
When gram-positive bacteria detect high concentration of AIPs in their environment, that happens by way of AIPs binding to a receptor to activate a kinase. The kinase phosphorylates a transcription factor, which regulates gene transcription. This is called a two-component system.
Another possible mechanism is that AIP is transported into the cytosol, and binds directly to a transcription factor to initiate or inhibit transcription. | 1 | Applied and Interdisciplinary Chemistry |
Higher values of TFQI are associated with obesity, metabolic syndrome, impaired renal function, diabetes, and diabetes-related mortality. In a large population of community-dwelling euthyroid subjects the thyroid feedback quantile-based index predicted all-cause mortality, even after adjustment for other established risk factors and comorbidities.
A cross-sectional study from Spain observed increased prevalence of type 2 diabetes, atrial fibrillation, ischemic heart disease and hypertension in persons with elevated PTFQI.
Serum Concentrations of Adipocyte Fatty Acid-Binding Protein (A-FABP) are significantly correlateted to TFQI, suggesting some form of cross-talk between adipose tissue and HPT axis.
TFQI results are also elevated in takotsubo syndrome, potentially reflecting type 2 allostatic load in the situation of psychosocial stress. Reductions have been observed in subjects with schizophrenia after initiation of therapy with oxcarbazepine and quetiapine, potentially reflecting declining allostatic load.
Despite positive association to metabolic syndrome and type 2 allostatic load a large population-based study failed to identify an association to risks of dyslipidemia and non-alcoholic fatty liver disease (NAFLD). | 1 | Applied and Interdisciplinary Chemistry |
The body's acid–base balance is tightly regulated. Several buffering agents exist which reversibly bind hydrogen ions and impede any change in pH. Extracellular buffers include bicarbonate and ammonia, while proteins and phosphate act as intracellular buffers. The bicarbonate buffering system is especially key, as carbon dioxide (CO) can be shifted through carbonic acid (HCO) to hydrogen ions and bicarbonate (HCO) as shown below.
Acid–base imbalances that overcome the buffer system can be compensated in the short term by changing the rate of ventilation. This alters the concentration of carbon dioxide in the blood, shifting the above reaction according to Le Chateliers principle, which in turn alters the pH. For instance, if the blood pH drops too low (acidemia), the body will compensate by increasing breathing, expelling CO, and shifting the reaction above to the right such that fewer hydrogen ions are free–thus the pH will rise back to normal. For alkalemia', the opposite occurs.
The kidneys are slower to compensate, but renal physiology has several powerful mechanisms to control pH by the excretion of excess acid or base. In responses to acidosis, tubular cells reabsorb more bicarbonate from the tubular fluid, collecting duct cells secrete more hydrogen and generate more bicarbonate, and ammoniagenesis leads to increased formation of the NH buffer. In responses to alkalosis, the kidney may excrete more bicarbonate by decreasing hydrogen ion secretion from the tubular epithelial cells, and lowering rates of glutamine metabolism and ammonia excretion. | 0 | Theoretical and Fundamental Chemistry |
Biological activities of metal ion-binding compounds can be changed in response to the increment of the metal concentration, and based on the latter compounds can be classified as "metal ionophores", "metal chelators" or "metal shuttles". If the biological effect is augmented by increasing the metal concentration, it is classified as a "metal ionophore". If the biological effect is decreased or reversed by increasing the metal concentration, it is classified as a "metal chelator". If the biological effect is not affected by increasing the metal concentration, and the compound-metal complex enters the cell, it is classified as a "metal shuttle". The term ionophore (from Greek ion carrier or ion bearer) was proposed by Berton Pressman in 1967 when he and his colleagues were investigating the antibiotic mechanisms of valinomycin and nigericin.
Many ionophores are produced naturally by a variety of microbes, fungi and plants, and act as a defense against competing or pathogenic species. Multiple synthetic membrane-spanning ionophores have also been synthesized.
The two broad classifications of ionophores synthesized by microorganisms are:
*Carrier ionophores that bind to a particular ion and shield its charge from the surrounding environment. This makes it easier for the ion to pass through the hydrophobic interior of the lipid membrane. However, these ionophores become unable to transport ions under very low temperatures. An example of a carrier ionophore is valinomycin, a molecule that transports a single potassium cation. Carrier ionophores may be proteins or other molecules.
*Channel formers that introduce a hydrophilic pore into the membrane, allowing ions to pass through without coming into contact with the membrane's hydrophobic interior. Channel forming ionophores are usually large proteins. This type of ionophores can maintain their ability to transfer ions at low temperatures, unlike carrier ionophores. Examples of channel-forming ionophores are gramicidin A and nystatin.
Ionophores that transport hydrogen ions (H, i.e. protons) across the cell membrane are called protonophores. Iron ionophores and chelating agents are collectively called siderophores. | 0 | Theoretical and Fundamental Chemistry |
The main uses of nephelometers relate to air quality measurement for pollution monitoring, climate monitoring, and visibility. Airborne particles are commonly either biological contaminants, particulate contaminants, gaseous contaminants, or dust.
The accompanying chart shows the types and sizes of various particulate contaminants. This information helps understand the character of particulate pollution inside a building or in the ambient air, as well as the cleanliness level in a controlled environment.
Biological contaminants include mold, fungus, bacteria, viruses, animal dander, dust mites, pollen, human skin cells, cockroach parts, or anything alive or living at one time. They are the biggest enemy of indoor air quality specialists because they are contaminants that cause health problems. Levels of biological contamination depend on humidity and temperature that supports the livelihood of micro-organisms. The presence of pets, plants, rodents, and insects will raise the level of biological contamination. | 0 | Theoretical and Fundamental Chemistry |
An acid–alkali reaction is a special case of an acid–base reaction, where the base used is also an alkali. When an acid reacts with an alkali salt (a metal hydroxide), the product is a metal salt and water. Acid–alkali reactions are also neutralization reactions.
In general, acid–alkali reactions can be simplified to
by omitting spectator ions.
Acids are in general pure substances that contain hydrogen cations () or cause them to be produced in solutions. Hydrochloric acid () and sulfuric acid () are common examples. In water, these break apart into ions:
The alkali breaks apart in water, yielding dissolved hydroxide ions: | 0 | Theoretical and Fundamental Chemistry |
Apoptotic cells degrade their DNA in a characteristic nucleosome ladder pattern. This generates DNA fragments that can be ligated and amplified during the DamID procedure (van Steensel laboratory, unpublished observations). The influence of these nucleosomal fragments on the binding profile of a protein is not known. | 1 | Applied and Interdisciplinary Chemistry |
MedChemComm publishes Research Articles (original scientific work, usually between 4-10 pages in length) and Reviews (critical analyses of specialist areas). | 1 | Applied and Interdisciplinary Chemistry |
Esters are widespread in nature and are widely used in industry. In nature, fats are, in general, triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Several billion kilograms of polyesters are produced industrially annually, important products being polyethylene terephthalate, acrylate esters, and cellulose acetate. | 0 | Theoretical and Fundamental Chemistry |
* Tikhomirov, Sergey Michailovich (1 (14) February 1905 – 25 November 1982) – Soviet political and economic figure. Member of the CPSU Central Committee (1956–1961).
* Furtseva, Catherine Alekseevna (24 November (7 December), 1910, Vishny Volochek – 25 October 1974, Moscow) – Soviet statesman and party leader. The Minister of Culture of the USSR from 1960 to 1974. | 1 | Applied and Interdisciplinary Chemistry |
Malate dehydrogenase is also involved in gluconeogenesis, the synthesis of glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by pyruvate carboxylase to form oxaloacetate, a citric acid cycle intermediate. In order to get the oxaloacetate out of the mitochondria, malate dehydrogenase reduces it to malate, and it then traverses the inner mitochondrial membrane. Once in the cytosol, the malate is oxidized back to oxaloacetate by cytosolic malate dehydrogenase. Finally, phosphoenolpyruvate carboxykinase (PEPCK) converts oxaloacetate to phosphoenolpyruvate (PEP). | 1 | Applied and Interdisciplinary Chemistry |
Bromophenol blue is also used as a dye. At neutral pH, the dye absorbs red light most strongly and transmits blue light. (Its peak absorbance is 590 nm at a basic pH of 12.) Solutions of the dye, therefore, are blue. At low pH, the dye absorbs ultraviolet and blue light most strongly and appears yellow in solution.
In solution at pH 3.6 (in the middle of the transition range of this pH indicator) obtained by dissolution in water without any pH adjustment, bromophenol blue has a characteristic green red colour, where the apparent colour shifts depending on the concentration and/or path length through which the solution is observed. This phenomenon is called dichromatic color. Bromophenol blue is the substance with the highest known value of Kreft's dichromaticity index. This means it has the largest change in colour hue, when the thickness or concentration of observed sample increases or decreases. | 0 | Theoretical and Fundamental Chemistry |
This photosystem is known as PSI because it was discovered before Photosystem II, although future experiments showed that Photosystem II is actually the first enzyme of the photosynthetic electron transport chain. Aspects of PSI were discovered in the 1950s, but the significance of these discoveries was not yet recognized at the time. Louis Duysens first proposed the concepts of Photosystems I and II in 1960, and, in the same year, a proposal by Fay Bendall and Robert Hill assembled earlier discoveries into a coherent theory of serial photosynthetic reactions. Hill and Bendall's hypothesis was later confirmed in experiments conducted in 1961 by the Duysens and Witt groups. | 0 | Theoretical and Fundamental Chemistry |
*Nature-based solutions (European Union)
*Water-sensitive urban design (Australia)
*Sponge city (China)
*[https://www.pub.gov.sg/abcwaters ABC water] (Singapore) | 1 | Applied and Interdisciplinary Chemistry |
Although PFASs are not manufactured in Canada, they may be present in imported goods and products. In 2008, Canada prohibited the import, sale, or use of PFOS or PFOS-containing products, with some exceptions for products used in firefighting, the military, and some forms of ink and photo media.
Health Canada has published drinking water guidelines for maximum concentrations of PFOS and PFOA to protect the health of Canadians, including children, over a lifetime's exposure to these substances. The maximum allowable concentration for PFOS under the guidelines is 0.0002 milligrams per litre. The maximum allowable concentration for PFOA is 0.0006 milligrams per litre. | 0 | Theoretical and Fundamental Chemistry |
The copper coulometer is a one application for the copper-copper(II) sulfate electrode. Such a coulometer consists of two identical copper electrodes immersed in slightly acidic pH-buffered solution of copper(II) sulfate. Passing of current through the element leads to the anodic dissolution of the metal on anode and simultaneous deposition of copper ions on the cathode. These reactions have 100% efficiency over a wide range of current density. | 0 | Theoretical and Fundamental Chemistry |
CellCognition uses a computational pipeline which includes image segmentation, object detection, feature extraction, statistical classification, tracking of individual cells over time, detection of class-transition motifs (e.g. cells entering mitosis), and HMM correction of classification errors on class labels.
The software is written in Python 2.7 and binaries are available for Windows and Mac OS X. | 1 | Applied and Interdisciplinary Chemistry |
In bypass transition flow, the pre-transitional flow structures are different from those of very low turbulence free-stream flow. Through various laboratory experiments and computational studies, it has been observed that low frequency streaky flow structures are present in the laminar boundary layers. These streaky structures are called Klebanoff modes or K-modes. | 1 | Applied and Interdisciplinary Chemistry |
Alvircept sudotox is a form of recombinant CD4 derived from Pneumonas aeruginosa exotoxin A, or 'PE40, which has a size of 59,187 daltons and is an anti-viral agent. | 1 | Applied and Interdisciplinary Chemistry |
Glass microspheres are microscopic spheres of glass manufactured for a wide variety of uses in research, medicine, consumer goods and various industries. Glass microspheres are usually between 1 and 1000 micrometers in diameter, although the sizes can range from 100 nanometers to 5 millimeters in diameter. Hollow glass microspheres, sometimes termed microballoons or glass bubbles, have diameters ranging from 10 to 300 micrometers.
Hollow spheres are used as a lightweight filler in composite materials such as syntactic foam and lightweight concrete. Microballoons give syntactic foam its light weight, low thermal conductivity, and a resistance to compressive stress that far exceeds that of other foams. These properties are exploited in the hulls of submersibles and deep-sea oil drilling equipment, where other types of foam would implode. Hollow spheres of other materials create syntactic foams with different properties: ceramic balloons e.g. can make a light syntactic aluminium foam.
Hollow spheres also have uses ranging from storage and slow release of pharmaceuticals and radioactive tracers to research in controlled storage and release of hydrogen. Microspheres are also used in composites to fill polymer resins for specific characteristics such as weight, sandability and sealing surfaces. When making surfboards for example, shapers seal the EPS foam blanks with epoxy and microballoons to create an impermeable and easily sanded surface upon which fiberglass laminates are applied.
Glass microspheres can be made by heating tiny droplets of dissolved water glass in a process known as ultrasonic spray pyrolysis (USP), and properties can be improved somewhat by using a chemical treatment to remove some of the sodium. Sodium depletion has also allowed hollow glass microspheres to be used in chemically sensitive resin systems, such as long pot life epoxies or non-blown polyurethane composites.
Additional functionalities, such as silane coatings, are commonly added to the surface of hollow glass microspheres to increase the matrix/microspheres interfacial strength (the common failure point when stressed in a tensile manner).
Microspheres made of high quality optical glass, can be produced for research on the field of optical resonators or cavities.
Glass microspheres are also produced as waste product in coal-fired power stations. In this case the product would be generally termed "cenosphere" and carry an aluminosilicate chemistry (as opposed to the sodium silica chemistry of engineered spheres). Small amounts of silica in the coal are melted and as they rise up the chimneystack, expand and form small hollow spheres. These spheres are collected together with the ash, which is pumped in a water mixture to the resident ash dam. Some of the particles do not become hollow and sink in the ash dams, while the hollow ones float on the surface of the dams. They become a nuisance, especially when they dry, as they become airborne and blow over into surrounding areas. | 0 | Theoretical and Fundamental Chemistry |
Corundum is the name for a structure prototype in inorganic solids, derived from the namesake polymorph of aluminum oxide (α-AlO). Other compounds, especially among the inorganic solids, exist in corundum structure, either in ambient or other conditions. Corundum structures are associated with metal-insulator transition, ferroelectricity, polar magnetism, and magnetoelectric effects. | 0 | Theoretical and Fundamental Chemistry |
The synthesis and degradation of (p)ppGpp have been most extensively characterized in the bacterial model organism Escherichia coli. | 1 | Applied and Interdisciplinary Chemistry |
Training & Education program offers scientific, regulatory, and professional development training courses in person at the Annual Meeting and Midyear Meeting and as online courses and webinars. | 0 | Theoretical and Fundamental Chemistry |
Overall, the evolution of light producing cells (photocytes) is believed to have happened twice in sharks through convergence. Evidence suggests that the bioluminescent properties of the shark, Etmopterus spinax, came about as a mechanism of camouflage. It is thought that luminescence has other functions as well due to camouflage not being a logical explanation for the luminescence on the lateral sides of the shark. Bioluminescence is believed to have only evolved in sharks among the cartilaginous fishes. The function of bioluminescence among sharks has not been fully ascertained. | 1 | Applied and Interdisciplinary Chemistry |
Wrought iron is no longer made. The particles of slag present in the iron after preparation by puddling were drawn into long fibres during the forging or rolling process. The proportion of slag was intended to be about 3%, but the process was difficult to control and examples with up to 10% slag were produced. | 1 | Applied and Interdisciplinary Chemistry |
The PPM family, which includes PP2C and pyruvate dehydrogenase phosphatase, are enzymes with Mn/Mg metal ions that are resistant to classic inhibitors and toxins of the PPP family. Unlike most PPPs, PP2C exists in only one subunit but, like PTPs, it displays a wide variety of structural domains that confer unique functions. In addition, PP2C does not seem to be evolutionarily related to the major family of Ser/Thr PPs and has no sequence homology to ancient PPP enzymes. The current assumption is that PPMs evolved separately from PPPs but converged during evolutionary development. | 1 | Applied and Interdisciplinary Chemistry |
Some azides are valuable as bioorthogonal chemical reporters, molecules that can be "clicked" to see the metabolic path it has taken inside a living system.
The antiviral drug zidovudine (AZT) contains an azido group. | 0 | Theoretical and Fundamental Chemistry |
Studies of solid single- and double-base propellant reactions suggest a series of zones or phases as the reaction proceeds from the surface into the solid. The deepest portion of the solid experiencing heat transfer melts and begins phase transition from solid to gas in a foam zone. The gaseous propellant decomposes into simpler molecules in a surrounding fizz zone. Energy is released in a luminous outer flame zone where the simpler gas molecules react to form conventional combustion products like steam and carbon monoxide. Propellants designed for a minimum heat transfer pressure may fail to sustain the flame zone at lower pressures. | 0 | Theoretical and Fundamental Chemistry |
The reagent appears as a clear, yellow liquid without odour. It is harmful if inhaled, a recognised carcinogen and can cause eye burns. | 0 | Theoretical and Fundamental Chemistry |
Azolla has been deemed a "super-plant" as it can draw down as much as a tonne of nitrogen per acre per year (0.25 kg/m/yr); this is matched by 6 tonnes per acre of carbon drawdown (1.5 kg/m/yr). Its ability to use atmospheric nitrogen for growth means that the main limit to its growth is usually the availability of phosphorus: carbon, nitrogen and sulphur being three of the key elements of proteins, and phosphorus being required for DNA, RNA and in energy metabolism. The plant can grow at great speed in favourable conditions – modest warmth and 20 hours of sunlight, both of which were in evidence at the poles during the early Eocene – and can double its biomass over two to three days in such a climate. This rate of growth pushes the plants deep under away from sunlight where death and carbon sequestration occur. | 1 | Applied and Interdisciplinary Chemistry |
When atoms join into molecules, their inner electrons remain bound to their original nucleus while the outer valence electrons are distributed around the molecule. The charge distribution of these valence electrons determines the electronic energy level of a molecule, and can be described by molecular orbital theory, which closely follows the atomic orbital theory used for single atoms. Assuming that the momenta of the electrons are on the order of ħ/a (where ħ is the reduced Planck's constant and a is the average internuclear distance within a molecule, ~1Å), the magnitude of the energy spacing for electronic states can be estimated at a few electron volts. This is the case for most low-lying molecular energy states, and corresponds to transitions in the visible and ultraviolet regions of the electromagnetic spectrum.
In addition to the electronic energy levels shared with atoms, molecules have additional quantized energy levels corresponding to vibrational and rotational states. Vibrational energy levels refer to motion of the nuclei about their equilibrium positions in the molecule. The approximate energy spacing of these levels can be estimated by treating each nucleus as a quantum harmonic oscillator in the potential produced by the molecule, and comparing its associated frequency to that of an electron experiencing the same potential. The result is an energy spacing about 100x smaller than that for electronic levels. In agreement with this estimate, vibrational spectra show transitions in the near infrared (about 1 - 5 μm). Finally, rotational energy states describe semi-rigid rotation of the entire molecule and produce transition wavelengths in the far infrared and microwave regions (about 100-10,000 μm in wavelength). These are the smallest energy spacings, and their size can be understood by comparing the energy of a diatomic molecule with internuclear spacing ~1Å to the energy of a valence electron (estimated above as ~ħ/a).
Actual molecular spectra also show transitions which simultaneously couple electronic, vibrational, and rotational states. For example, transitions involving both rotational and vibrational states are often referred to as rotational-vibrational or rovibrational transitions. Vibronic transitions combine electronic and vibrational transitions, and rovibronic transitions combine electronic, rotational, and vibrational transitions. Due to the very different frequencies associated with each type of transition, the wavelengths associated with these mixed transitions vary across the electromagnetic spectrum. | 0 | Theoretical and Fundamental Chemistry |
The belt filter (sometimes called a belt press filter, or belt filter press) is an industrial machine, used for solid/liquid separation processes, particularly the dewatering of sludges in the chemical industry, mining and water treatment. Belt filter presses are also used in the production of apple juice, cider and winemaking. The process of filtration is primarily obtained by passing a pair of filtering cloths and belts through a system of rollers. The system takes a sludge or slurry as a feed, and separates it into a filtrate and a solid cake. | 1 | Applied and Interdisciplinary Chemistry |
The Naiyyayikas believe that the bondage of the world is due to false knowledge, which can be removed by constantly thinking of its opposite (pratipakshabhavana), namely, the true knowledge. So the opening aphorism of the states that only the true knowledge lead to niḥśreyasa (liberation). But the Nyāya school also maintains that the Gods grace is essential for obtaining true knowledge. Jayanta, in his Nyayamanjari' describes salvation as a passive stage of self in its natural purity, unassociated with pleasure, pain, knowledge and willingness. | 1 | Applied and Interdisciplinary Chemistry |
* Lyophilized bovine plasma gamma globulin
* Coomassie brilliant blue 1
* 0.15 M NaCl
* Spectrophotometer and cuvettes or a mobile smartphone camera (RGBradford method).
* Micropipettes | 0 | Theoretical and Fundamental Chemistry |
Bili light. A type of phototherapy that uses blue light with a range of 420–470 nm, used to treat neonatal jaundice. | 0 | Theoretical and Fundamental Chemistry |
The reaction mechanism involves the formation of a positively charged halonium ion in a molecule that also contains a carboxylic acid (or other functional group that is a precursor to it). The oxygen of the carboxyl acts as a nucleophile, attacking to open the halonium ring and instead form a lactone ring. The reaction is usually performed under mildly basic conditions to increase the nucleophilicity of the carboxyl group. | 0 | Theoretical and Fundamental Chemistry |
Rubber elasticity refers to a property of crosslinked rubber: it can be stretched by up to a factor of 10 from its original length and, when released, returns very nearly to its original length. This can be repeated many times with no apparent degradation to the rubber. Rubber is a member of a larger class of materials called elastomers and it is difficult to overestimate their economic and technological importance. Elastomers have played a key role in the development of new technologies in the 20th century and make a substantial contribution to the global economy. Rubber elasticity is produced by several complex molecular processes and its explanation requires a knowledge of advanced mathematics, chemistry and statistical physics, particularly the concept of entropy. Entropy may be thought of as a measure of the thermal energy that is stored in a molecule.
Common rubbers, such as polybutadiene and polyisoprene (also called natural rubber), are produced by a process called polymerization. Very long molecules (polymers) are built up sequentially by adding short molecular backbone units through chemical reactions. A rubber polymer follows a random, zigzag path in three dimensions, intermingling with many other rubber molecules. An elastomer is created by the addition of a few percent of a cross linking molecule such as sulfur. When heated, the crosslinking molecule causes a reaction that chemically joins (bonds) two of the rubber molecules together at some point (a crosslink). Because the rubber molecules are so long, each one participates in many crosslinks with many other rubber molecules forming a continuous molecular network.
As a rubber band is stretched, some of the network chains are forced to become straight and this causes a decrease in their entropy. It is this decrease in entropy that gives rise to the elastic force in the network chains. | 0 | Theoretical and Fundamental Chemistry |
Volcanic gases were directly responsible for approximately 3% of all volcano-related deaths of humans between 1900 and 1986. Some volcanic gases kill by acidic corrosion; others kill by asphyxiation. Some volcanic gases including sulfur dioxide, hydrogen chloride, hydrogen sulfide and hydrogen fluoride react with other atmospheric particles to form aerosols. | 1 | Applied and Interdisciplinary Chemistry |
The total boron (B) is the sum of boron species in a solution. In the environment these species usually include boric acid and borate, for example:
:B = [] + []
where
*B is the total boron concentration
*[] is the dihydrogen borate concentration
*[] is the boric acid concentration
Total boron is an important quantity when determining alkalinity due to borates contribution to a solutions acid neutraling capacity. Total boron is a conservative element in seawater, and can thus be calculated by simply knowing the salinity. | 0 | Theoretical and Fundamental Chemistry |
SMAs display a phenomenon sometimes called superelasticity, but is more accurately described as pseudoelasticity. “Superelasticity” implies that the atomic bonds between atoms stretch to an extreme length without incurring plastic deformation. Pseudoelasticity still achieves large, recoverable strains with little to no permanent deformation, but it relies on more complex mechanisms.
SMAs exhibit at least 3 kinds of pseudoelasticty. The two less-studied kinds of pseudoelasticity are pseudo-twin formation and rubber-like behavior due to short range order.
The main pseudoelastic effect comes from a stress-induced phase transformation. The figure on the right exhibits how this process occurs.
Here a load is isothermally applied to a SMA above the austenite finish temperature, A, but below the martensite deformation temperature, M. The figure above illustrates how this is possible, by relating the pseudoelastic stress-induced phase transformation to the shape memory effect temperature induced phase transformation. For a particular point on A it is possible to choose a point on the M line with a higher temperature, as long as that point M also has a higher stress. The material initially exhibits typical elastic-plastic behavior for metals. However, once the material reaches the martensitic stress, the austenite will transform to martensite and detwin. As previously discussed, this detwinning is reversible when transforming back from martensite to austenite. If large stresses are applied, plastic behavior such as detwinning and slip of the martensite will initiate at sites such as grain boundaries or inclusions. If the material is unloaded before plastic deformation occurs, it will revert to austenite once a critical stress for austenite is reached (σ). The material will recover nearly all strain that was induced from the structural change, and for some SMAs this can be strains greater than 10 percent. This hysteresis loop shows the work done for each cycle of the material between states of small and large deformations, which is important for many applications.
In a plot of strain versus temperature, the austenite and martensite start and finish lines run parallel. The SME and pseudoelasticity are actually different parts of the same phenomenon, as shown on the left.
The key to the large strain deformations is the difference in crystal structure between the two phases. Austenite generally has a cubic structure while martensite can be monoclinic or another structure different from the parent phase, typically with lower symmetry. For a monoclinic martensitic material such as Nitinol, the monoclinic phase has lower symmetry which is important as certain crystallographic orientations will accommodate higher strains compared to other orientations when under an applied stress. Thus it follows that the material will tend to form orientations that maximize the overall strain prior to any increase in applied stress. One mechanism that aids in this process is the twinning of the martensite phase. In crystallography, a twin boundary is a two-dimensional defect in which the stacking of atomic planes of the lattice are mirrored across the plane of the boundary. Depending on stress and temperature, these deformation processes will compete with permanent deformation such as slip.
It is important to note that σ is dependent on parameters such as temperature and the number of nucleation sites for phase nucleation. Interfaces and inclusions will provide general sites for the transformation to begin, and if these are great in number, it will increase the driving force for nucleation. A smaller σ will be needed than for homogeneous nucleation. Likewise, increasing temperature will reduce the driving force for the phase transformation, so a larger σ will be necessary. One can see that as you increase the operational temperature of the SMA, σ will be greater than the yield strength, σ, and superelasticity will no longer be observable. | 1 | Applied and Interdisciplinary Chemistry |
Glass-ceramic materials share many properties with both non-crystalline glasses and crystalline ceramics. They are formed as a glass, and then partially crystallized by heat treatment, producing both amorphous and crystalline phases so that crystalline grains are embedded within a non-crystalline intergranular phase.
Glass-ceramics are used to make cookware (originally known by the brand name CorningWare) and stovetops that have both high resistance to thermal shock and extremely low permeability to liquids. The negative coefficient of thermal expansion of the crystalline ceramic phase can be balanced with the positive coefficient of the glassy phase. At a certain point (~70% crystalline) the glass-ceramic has a net coefficient of thermal expansion close to zero. This type of glass-ceramic exhibits excellent mechanical properties and can sustain repeated and quick temperature changes up to 1000 °C.
Glass ceramics may also occur naturally when lightning strikes the crystalline (e.g. quartz) grains found in most beach sand. In this case, the extreme and immediate heat of the lightning (~2500 °C) creates hollow, branching rootlike structures called fulgurite via fusion. | 0 | Theoretical and Fundamental Chemistry |
The basic leaching chemical formula that drives this process is:
This is achieved in practice through a process called double leaching. The calcine is first leached in a neutral or slightly acidic solution (of sulfuric acid) in order to leach the zinc out of the zinc oxide. The remaining calcine is then leached in strong sulfuric acid to leach the rest of the zinc out of the zinc oxide and zinc ferrite. The result of this process is a solid and a liquid; the liquid contains the zinc and is often called leach product; the solid is called leach residue and contains precious metals (usually lead and silver) which are sold as a by-product. There is also iron in the leach product from the strong acid leach, which is removed in an intermediate step, in the form of goethite, jarosite, and haematite. There is still cadmium, copper, arsenic, antimony, cobalt, germanium, nickel, and thallium in the leach product. Therefore, it needs to be purified. | 1 | Applied and Interdisciplinary Chemistry |
Radioactive waste is a type of hazardous waste that contains radioactive material. Radioactive waste is a result of many activities, including nuclear medicine, nuclear research, nuclear power generation, nuclear decommissioning, rare-earth mining, and nuclear weapons reprocessing. The storage and disposal of radioactive waste is regulated by government agencies in order to protect human health and the environment.
Radioactive waste is broadly classified into 3 categories: low-level waste (LLW), such as paper, rags, tools, clothing, which contain small amounts of mostly short-lived radioactivity; intermediate-level waste (ILW), which contains higher amounts of radioactivity and requires some shielding; and high-level waste (HLW), which is highly radioactive and hot due to decay heat, thus requiring cooling and shielding.
In nuclear reprocessing plants about 96% of spent nuclear fuel is recycled back into uranium-based and mixed-oxide (MOX) fuels. The residual 4% is minor actinides and fission products the latter of which are a mixture of stable and quickly decaying (most likely already having decayed in the spent fuel pool) elements, medium lived fission products such as strontium-90 and caesium-137 and finally seven long-lived fission products with half lives in the hundreds of thousands to millions of years. The minor actinides meanwhile are heavy elements other than uranium and plutonium which are created by neutron capture. Their half lives range from years to millions of years and as alpha emitters they are particularly radiotoxic. While there are proposed - and to a much lesser extent current - uses of all those elements, commercial scale reprocessing using the PUREX-process disposes of them as waste together with the fission products. The waste is subsequently converted into a glass-like ceramic for storage in a deep geological repository.
The time radioactive waste must be stored for depends on the type of waste and radioactive isotopes it contains. Short-term approaches to radioactive waste storage have been segregation and storage on the surface or near-surface. Burial in a deep geological repository is a favored solution for long-term storage of high-level waste, while re-use and transmutation are favored solutions for reducing the HLW inventory. Boundaries to recycling of spent nuclear fuel are regulatory and economic as well as the issue of radioactive contamination if chemical separation processes cannot achieve a very high purity. Furthermore, elements may be present in both useful and troublesome isotopes, which would require costly and energy intensive isotope separation for their use - a currently uneconomic prospect.
A summary of the amounts of radioactive waste and management approaches for most developed countries are presented and reviewed periodically as part of a joint convention of the International Atomic Energy Agency (IAEA). | 0 | Theoretical and Fundamental Chemistry |
Zeotropic mixtures that are used in refrigeration are assigned a number in the 400 series to help identify its component and their proportions as a part of nomenclature. Whereas for azeotropic mixtures they are assigned a number in the 500 series. According to ASHRAE, refrigerants names start with R followed by a series of numbers—400 series if it is zeotropic or 500 if it is azeotropic—followed by uppercase letters that denote the composition.
Research has proposed using zeotropic mixtures as substitutes to halogenated refrigerants due to the harmful effects that hydrochlorofluorocarbons (HCFC) and chlorofluorocarbons (CFC) have on the ozone layer and global warming. Researchers have focused on using new mixtures that have the same properties as past refrigerants to phase out harmful halogenated substances, in accordance to the Montreal Protocol and Kyoto Protocol. For example, researchers found that zeotropic mixture R-404A can replace R-12, a CFC, in household refrigerators. However, there are some technical difficulties for using zeotropic mixtures. This includes leakages, as well as the high temperature glide associated with substances of different boiling points, though the temperature glide can be matched to the temperature difference between the two refrigerants when exchanging heat to increase efficiency. Replacing pure refrigerants with mixtures calls for more research on the environmental impact as well as the flammability and safety of refrigerant mixtures. | 1 | Applied and Interdisciplinary Chemistry |
*Goldschmidt was created a Knight of the Order of St. Olav in 1929.
*While at the Macaulay Institute, Goldschmidt was elected a Foreign Member of the Royal Society, given an honorary Doctor of Laws (LLD) by the University of Aberdeen and awarded the Wollaston Medal, the highest honor of the Geological Society of London.
*The mountain ridge Goldschmidtfjella in Oscar II Land at Spitsbergen is named after him.
*The mineral goldschmidtite (KNbO) was named in his honour (IMA2018-034).
*The V. M. Goldschmidt Medal is awarded annually by The Geochemical Society | 0 | Theoretical and Fundamental Chemistry |
The most popular methods rely on adsorbing floral VOCs on an adsorbent material such as SPME fibers or cartridges by pumping air sampled around inflorescences through the adsorbent material.
It is also possible to extract chemicals stocked in petals by immersing them in a solvent and then analyze the liquid residue. This is more adapted to the study of heavier organic compounds, and/or VOCs that are stored in floral tissue before being emitted into air. | 1 | Applied and Interdisciplinary Chemistry |
Most protein separations are performed using a "discontinuous" (or DISC) buffer system that significantly enhances the sharpness of the bands within the gel. During electrophoresis in a discontinuous gel system, an ion gradient is formed in the early stage of electrophoresis that causes all of the proteins to focus into a single sharp band. The formation of the ion gradient is achieved by choosing a pH value at which the ions of the buffer are only moderately charged compared to the SDS-coated proteins. These conditions provide an environment in which Kohlrausch's reactions determine the molar conductivity. As a result, SDS-coated proteins are concentrated to several fold in a thin zone of the order of 19 μm within a few minutes. At this stage all proteins migrate at the same migration speed by isotachophoresis. This occurs in a region of the gel that has larger pores so that the gel matrix does not retard the migration during the focusing or "stacking" event. Separation of the proteins by size is achieved in the lower, "resolving" region of the gel. The resolving gel typically has a much smaller pore size, which leads to a sieving effect that now determines the electrophoretic mobility of the proteins. At the same time, the separating part of the gel also has a pH value in which the buffer ions on average carry a greater charge, causing them to "outrun" the SDS-covered proteins and eliminate the ion gradient and thereby the stacking effect.
A very widespread discontinuous buffer system is the tris-glycine or "Laemmli" system that stacks at a pH of 6.8 and resolves at a pH of ~8.3-9.0. A drawback of this system is that these pH values may promote disulfide bond formation between cysteine residues in the proteins because the pKa of cysteine ranges from 8-9 and because reducing agent present in the loading buffer doesn't co-migrate with the proteins. Recent advances in buffering technology alleviate this problem by resolving the proteins at a pH well below the pKa of cysteine (e.g., bis-tris, pH 6.5) and include reducing agents (e.g. sodium bisulfite) that move into the gel ahead of the proteins to maintain a reducing environment. An additional benefit of using buffers with lower pH values is that the acrylamide gel is more stable at lower pH values, so the gels can be stored for long periods of time before use. | 1 | Applied and Interdisciplinary Chemistry |
In a mass of continuum that is rotating like a rigid body, the vorticity is twice the angular velocity vector of that rotation. This is the case, for example, in the central core of a Rankine vortex.
The vorticity may be nonzero even when all particles are flowing along straight and parallel pathlines, if there is shear (that is, if the flow speed varies across streamlines). For example, in the laminar flow within a pipe with constant cross section, all particles travel parallel to the axis of the pipe; but faster near that axis, and practically stationary next to the walls. The vorticity will be zero on the axis, and maximum near the walls, where the shear is largest.
Conversely, a flow may have zero vorticity even though its particles travel along curved trajectories. An example is the ideal irrotational vortex, where most particles rotate about some straight axis, with speed inversely proportional to their distances to that axis. A small parcel of continuum that does not straddle the axis will be rotated in one sense but sheared in the opposite sense, in such a way that their mean angular velocity about their center of mass is zero.
Another way to visualize vorticity is to imagine that, instantaneously, a tiny part of the continuum becomes solid and the rest of the flow disappears. If that tiny new solid particle is rotating, rather than just moving with the flow, then there is vorticity in the flow. In the figure below, the left subfigure demonstrates no vorticity, and the right subfigure demonstrates existence of vorticity. | 1 | Applied and Interdisciplinary Chemistry |
Gradation affects many properties of an aggregate, including bulk density, physical stability and permeability. With careful selection of the gradation, it is possible to achieve high bulk density, high physical stability, and low permeability. This is important because in pavement design, a workable, stable mix with resistance to water is important. With an open gradation, the bulk density is relatively low, due to the lack of fine particles, the physical stability is moderate, and the permeability is quite high. With a rich gradation, the bulk density will also be low, the physical stability is low, and the permeability is also low. The gradation can be affected to achieve the desired properties for the particular engineering application. | 1 | Applied and Interdisciplinary Chemistry |
These relations can be quite complicated; a simple case is shown here: the decay scheme of the radioactive cobalt isotope cobalt-60. Co decays by emitting an electron (beta decay) with a half-life of 5.272 years into an excited state of Ni, which then decays very fast to the ground state of Ni, via two gamma decays.
All known decay schemes can be found in the Table of Isotopes.,
Nickel is to the right of cobalt, since its proton number (28) is higher by one than that of cobalt (27). In beta decay, the proton number increases by one. For a positron decay and also for an alpha decay (see below), the oblique arrow would go from right to left since in these cases, the proton number decreases.
Since energy is conserved and since the particles emitted carry away energy, arrows can only go downward (vertically or at an angle) in a decay scheme.
A somewhat more complicated scheme is shown here: the decay of the nuclide Au which can be produced by irradiating natural gold in a nuclear reactor. Au decays via beta decay to one of two excited states or to the ground state of the mercury isotope Hg. In the figure, mercury is to the right of gold, since the atomic number of gold is 79, that of mercury is 80. The excited states decay after very short times (2.5 and 23 ps, resp.; 1 picosecond is a millionth of a millionth of a second) to the ground state.
While excited nuclear states are usually very short lived, decaying almost immediately after a beta decay (see above), the excited state of the technetium isotope shown here to the right is comparatively long lived. It is therefore called "metastable" (hence the "m" in Tc ). It decays to the ground state via gamma decay with a half-life of 6 hours.
Here, to the left, we now have an alpha decay. It is the decay of the element Polonium discovered by Marie Curie, with mass number 210. The isotope Po is the penultimate member of the uranium-radium-decay series; it decays into a stable lead-isotope with a half-life of 138 days. In almost all cases, the decay is via the emission of an alpha particle of 5.305 MeV. Only in one case of 100000, an alpha particle of lower energy appears; in this case, the decay leads to an excited level of Pb, which then decays to the ground state via gamma radiation. | 0 | Theoretical and Fundamental Chemistry |
Gregory M. Fahy is a California-based cryobiologist, biogerontologist, and businessman. He is Vice President and Chief Scientific Officer at Twenty-First Century Medicine, Inc, and has co-founded Intervene Immune, a company developing clinical methods to reverse immune system aging. He is the 2022–2023 president of the Society for Cryobiology. | 1 | Applied and Interdisciplinary Chemistry |
Libby's first detector was a Geiger counter of his own design. He converted the carbon in his sample to lamp black (soot) and coated the inner surface of a cylinder with it. This cylinder was inserted into the counter in such a way that the counting wire was inside the sample cylinder, in order that there should be no material between the sample and the wire. Any interposing material would have interfered with the detection of radioactivity, since the beta particles emitted by decaying are so weak that half are stopped by a thickness of aluminium.
Libby's method was soon superseded by gas proportional counters, which were less affected by bomb carbon (the additional created by nuclear weapons testing). These counters record bursts of ionization caused by the beta particles emitted by the decaying atoms; the bursts are proportional to the energy of the particle, so other sources of ionization, such as background radiation, can be identified and ignored. The counters are surrounded by lead or steel shielding, to eliminate background radiation and to reduce the incidence of cosmic rays. In addition, anticoincidence detectors are used; these record events outside the counter and any event recorded simultaneously both inside and outside the counter is regarded as an extraneous event and ignored.
The other common technology used for measuring activity is liquid scintillation counting, which was invented in 1950, but which had to wait until the early 1960s, when efficient methods of benzene synthesis were developed, to become competitive with gas counting; after 1970 liquid counters became the more common technology choice for newly constructed dating laboratories. The counters work by detecting flashes of light caused by the beta particles emitted by as they interact with a fluorescing agent added to the benzene. Like gas counters, liquid scintillation counters require shielding and anticoincidence counters.
For both the gas proportional counter and liquid scintillation counter, what is measured is the number of beta particles detected in a given time period. Since the mass of the sample is known, this can be converted to a standard measure of activity in units of either counts per minute per gram of carbon (cpm/g C), or becquerels per kg (Bq/kg C, in SI units). Each measuring device is also used to measure the activity of a blank sample – a sample prepared from carbon old enough to have no activity. This provides a value for the background radiation, which must be subtracted from the measured activity of the sample being dated to get the activity attributable solely to that sample's . In addition, a sample with a standard activity is measured, to provide a baseline for comparison. | 0 | Theoretical and Fundamental Chemistry |
The thermodynamic activity of volatiles needs to be higher in the polymer than in the other phase for them to leave the polymer. In order to design such a process, the activity needs to be calculated. This is usually done via the Flory–Huggins solution theory. This effect can be enhanced via higher temperatures or lower partial pressure of the volatile component by applying an inert gas or lower pressure. | 1 | Applied and Interdisciplinary Chemistry |
There are a number of common formats for performing gel filtration for smaller (less than 4mL) volumes:
* Chromatography columns
* Gravity-flow columns
* Chromatography cartridges
* Centrifuge columns
* Centrifuge plates
Gravity-flow, or drip, columns use head-pressure from a buffer-chase to push the sample through the gel filtration matrix. Sample is loaded into the top of an upright column and allowed to flow into the resin bed. The sample is then chased through the column by adding additional buffer or water to the top of the column. During this process, small fractions are typically collected and each is tested for the macromolecules of interest. In some cases, several fractions might contain the protein and may have to be pooled to improve yield. In order to eliminate the time and monitoring assorted with drip columns, fractions often equal to the full exclusion volume of the column are collected regardless of sample volume resulting in significant dilution of sample.
Sealed chromatography cartridges or columns work similarly except the sample and buffer is pumped into and through the resin by an external device such as a liquid chromatographic (LC) system, also requiring collection and monitoring of several fractions. Even though this method is often semi-automated, using chromatography cartridges is typically limited to processing one sample at a time and some sample dilution from the chase buffer is still likely to occur.
To eliminate sample dilution and the collecting and monitoring of fractions, centrifuge column or plate -based gel filtration, also referred to as spin desalting, methods are commonly used. Spin desalting is unique in that a centrifuge is used to first clear the void volume of liquid in the resin, followed by sample addition and centrifugation. After centrifugation, the macromolecules in the sample have moved through the column in approximately the same initial volume, but the small molecules have been forced into the pores of the resin and replaced by the buffer that was used to pre-equilibrate the gel-filtration matrix. Spin columns and plates eliminate the need to wait for samples to emerge by gravity flow and require no chromatography system, allowing for multiple-sample processing simultaneously. | 0 | Theoretical and Fundamental Chemistry |
RoXaN is capable of interacting with NSP3 in vivo and during rotavirus infection. Domains of interaction correspond to the dimerization domain of NSP3 (amino acids 163 to 237) and the LD domain of RoXaN (amino acids 244 to 341). The interaction between NSP3 and RoXaN does not impair the interaction between NSP3 and eIF4G I, and a ternary complex made of NSP3, RoXaN, and eIF4G I can be detected in rotavirus-infected cells, implicating RoXaN in translation regulation.
Expression of RoXaN was found to be correlated with a higher tumor grad in GIST (gastrointestinal stromal tumors). | 1 | Applied and Interdisciplinary Chemistry |
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by the PCAF gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. | 1 | Applied and Interdisciplinary Chemistry |
Trimmed sequences from the previous step are aligned to the reference genome using a Burrows–Wheeler aligner (BWA) and the unmapped reads are removed. The aligned reads that have the same 24-base pair tag sequence and genomic region are detected and grouped (family αβ and βα in Figure 2). Each group represents a “tag family.” Tag families with fewer than three members are not analyzed. To remove errors that arise during PCR amplification or sequencing, mutations that are supported by less than 70% of the members (reads) are filtered out from the analysis. A consensus sequence is then generated for each family using the identical sequences in each position of the remaining reads. The consensus sequence is called the SSCS. It increases the NGS accuracy to about 20 fold higher; however, this method relies on the sequencing information from single strands of DNA and therefore is sensitive to the errors induced at the first round or before PCR amplification. | 1 | Applied and Interdisciplinary Chemistry |
In Canada, the provinces of Quebec and Ontario were always RHT because they were created out of the former French colony of New France. The province of British Columbia changed to RHT in stages from 1920 to 1923, New Brunswick, Nova Scotia, and Prince Edward Island in 1922, 1923, and 1924 respectively, and the British colony of Newfoundland (part of Canada since 1949) in 1947, in order to allow traffic (without side switch) to or from the United States.
In the West Indies, colonies and territories drive on the same side as their parent countries, except for the United States Virgin Islands. Many of the island nations are former British colonies and drive on the left, including Jamaica, Antigua and Barbuda, Barbados, Dominica, Grenada, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines, Trinidad and Tobago, and The Bahamas. However, most vehicles in The Bahamas, Cayman Islands, Turks and Caicos Islands and both the British Virgin Islands, and the United States Virgin Islands are LHD due to their being imported from the United States.
Brazil, a Portuguese colony until the early 19th century, had in the 19th and the early 20th century mixed rules, with some regions still on LHT, switching these remaining regions to RHT in 1928, the same year Portugal switched sides. Other Central and South American countries that later switched from LHT to RHT include Argentina, Chile, Panama, Paraguay, and Uruguay.
Suriname, along with neighbouring Guyana, are the only two remaining LHT countries in South America. | 0 | Theoretical and Fundamental Chemistry |
In the late 20th century and early 21st century, some "health mines" were established in Basin, Montana, which attracted people seeking relief from health problems such as arthritis through limited exposure to radioactive mine water and radon. The practice is controversial because of the well-documented ill effects of high-dose radiation on the body. Pseudoscientific doctors claim beneficial long-term effects, although proper clinical trials have not been performed. The claim of the study is of concern as the authors excluded results from patients requiring cortisone injections as a result of exacerbation of their arthritis during the course of treatment. This study also assumes 60 patients represents all patients. This study also did not record if any patients taken any NSAIDS. The study also claims that the therapeutic benefit comes from the "integration of radon into the skin". | 1 | Applied and Interdisciplinary Chemistry |
A mode of vibration is characterized by a modal frequency and a mode shape. It is numbered according to the number of half waves in the vibration. For example, if a vibrating beam with both ends pinned displayed a mode shape of half of a sine wave (one peak on the vibrating beam) it would be vibrating in mode 1. If it had a full sine wave (one peak and one trough) it would be vibrating in mode 2.
In a system with two or more dimensions, such as the pictured disk, each dimension is given a mode number. Using polar coordinates, we have a radial coordinate and an angular coordinate. If one measured from the center outward along the radial coordinate one would encounter a full wave, so the mode number in the radial direction is 2. The other direction is trickier, because only half of the disk is considered due to the anti-symmetric (also called skew-symmetry) nature of a disk's vibration in the angular direction. Thus, measuring 180° along the angular direction you would encounter a half wave, so the mode number in the angular direction is 1. So the mode number of the system is 2–1 or 1–2, depending on which coordinate is considered the "first" and which is considered the "second" coordinate (so it is important to always indicate which mode number matches with each coordinate direction).
In linear systems each mode is entirely independent of all other modes. In general all modes have different frequencies (with lower modes having lower frequencies) and different mode shapes. | 0 | Theoretical and Fundamental Chemistry |
As of 2009 the total amount in the atmosphere is estimated at 5500 PBq due to anthropogenic sources. At the end of the year 2000, it was estimated to be 4800 PBq, and in 1973, an estimated 1961 PBq (53 megacuries). The most important of these human sources is nuclear fuel reprocessing, as krypton-85 is one of the seven common medium-lived fission products. Nuclear fission produces about three atoms of krypton-85 for every 1000 fissions (i.e., it has a fission yield of 0.3%). Most or all of this krypton-85 is retained in the spent nuclear fuel rods; spent fuel on discharge from a reactor contains between 0.13–1.8 PBq/Mg of krypton-85. Some of this spent fuel is reprocessed. Current nuclear reprocessing releases the gaseous Kr into the atmosphere when the spent fuel is dissolved. It would be possible in principle to capture and store this krypton gas as nuclear waste or for use. The cumulative global amount of krypton-85 released from reprocessing activity has been estimated as 10,600 PBq as of 2000. The global inventory noted above is smaller than this amount due to radioactive decay; a smaller fraction is dissolved into the deep oceans.
Other man-made sources are small contributors to the total. Atmospheric nuclear weapons tests released an estimated 111–185 PBq. The 1979 accident at the Three Mile Island nuclear power plant released about . The Chernobyl accident released about 35 PBq, and the Fukushima Daiichi accident released an estimated 44–84 PBq.
The average atmospheric concentration of krypton-85 was approximately 0.6 Bq/m in 1976, and has increased to approximately 1.3 Bq/m as of 2005. These are approximate global average values; concentrations are higher locally around nuclear reprocessing facilities, and are generally higher in the northern hemisphere than in the southern hemisphere.
For wide-area atmospheric monitoring, krypton-85 is the best indicator for clandestine plutonium separations.
Krypton-85 releases increase the electrical conductivity of atmospheric air. Meteorological effects are expected to be stronger closer to the source of the emissions. | 0 | Theoretical and Fundamental Chemistry |
The surface chemistry of paper is responsible for many important paper properties, such as gloss, waterproofing, and printability. Many components are used in the paper-making process that affect the surface. | 0 | Theoretical and Fundamental Chemistry |
To perform a pulsed EDMR experiment, the system is first initialised by placing it in a magnetic field. This orients the spins of the electrons occupying the donor and acceptor in the direction of the magnetic field. To study the donor, we apply a microwave pulse ("γ" in the diagram) at a resonant frequency of the donor. This flips the spin of the electron on the donor. The donor electron can then decay to the acceptor energy state (it was forbidden from doing that before it was flipped due to the Pauli exclusion principle) and from there to the valence band, where it recombines with a hole. With more recombination, there will be fewer conduction electrons in the conduction band and a corresponding increase in the resistance, which can be directly measured. Above-bandgap light is used throughout the experiment to ensure that there are many electrons in the conduction band.
By scanning the frequency of the microwave pulse, we can find which frequencies are resonant, and with knowledge of the strength of the magnetic field, we can identify the donors energy levels from the resonant frequency and knowledge of the Zeeman effect. The donors energy levels act as a fingerprint by which we can identify the donor and its local electronic environment. By changing the frequency slightly, we can study the acceptor instead. | 0 | Theoretical and Fundamental Chemistry |
Dendrimers also are used in the synthesis of monodisperse metallic nanoparticles. Poly(amidoamide), or PAMAM, dendrimers are utilized for their tertiary amine groups at the branching points within the dendrimer. Metal ions are introduced to an aqueous dendrimer solution and the metal ions form a complex with the lone pair of electrons present at the tertiary amines. After complexation, the ions are reduced to their zerovalent states to form a nanoparticle that is encapsulated within the dendrimer. These nanoparticles range in width from 1.5 to 10 nanometers and are called dendrimer-encapsulated nanoparticles. | 0 | Theoretical and Fundamental Chemistry |
Levacetylmethadol (INN), levomethadyl acetate (USAN), OrLAAM (trade name) or levo-α-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone. It has a long duration of action due to its active metabolites. | 0 | Theoretical and Fundamental Chemistry |
ZMapp was first used during the 2014 West Africa Ebola Virus outbreak, having not previously undergone any human clinical trials to determine its efficacy or potential risks. By October 2014, the United States Food and Drug Administration had approved the use of several experimental drugs, including ZMapp, to be used on patients infected with Ebola virus. The use of such drugs during the epidemic was also deemed ethical by the World Health Organization. In 2014, a limited supply of ZMapp was used to treat 7 individuals infected with the Ebola virus; of these 2 died. The outcome is not considered to be statistically significant. Mapp announced in August 2014, that supplies of ZMapp had been exhausted. | 1 | Applied and Interdisciplinary Chemistry |
In designing copolymers for thermally induced shape-memory effect it is very important to keep in mind that a slight change in chemical structure (cis/trans ratios, tacticity, molecular mass, etc.) produces a significant change in the shape-memory polymer. An example is the copolymer of poly(methylmethacrylate-co-methacrylic acid) or poly(MAA-co-MMA) compared to poly(MAA-co-MMA)-PEG, where PEG is short for poly(ethylene glycol) which forms complexes in the copolymer.
Changes in the morphology of the material including PEG provide shape-memory effect to the copolymer, showing two phases, the three-dimensional network providing a stable phase and the reversible phase formed by the amorphous part of the PEG-PMAA complexes. The complexes show a high modulus storage capacity, so when a PEG of higher molecular mass is introduced into the copolymer, an increase in the elastic modulus, higher modulus in the glassy state and faster recovery are observed.
Its properties can be studied with differential scanning calorimetry (DSC), wide-angle X-ray diffraction (WAXD) and dynamic mechanical analysis (DMA) techniques to determine its physicochemical arrangement. | 0 | Theoretical and Fundamental Chemistry |
Sophorolipids are glycolipids consisting of a hydrophobic fatty acid tail of 16 or 18 carbon atoms and a hydrophilic carbohydrate head sophorose, a glucose-derived di-saccharide with an unusual β-1,2 bond and can be acetylated on the 6′- and/or 6′′- positions. One terminal or sub terminal hydroxylated fatty acid is β-glycosidically linked to the sophorose module. The carboxylic end of this fatty acid is either free (acidic or open form) or internally esterified at the 4′′ or in some rare cases at the 6′- or 6′′-position (lactonic form). The physicochemical and biological properties of sophorolipids are significantly influenced by the distribution of the lactone vs. acidic forms produced in the fermentative broth. In general, lactone sophorolipids are more efficient in reducing surface tension and are better antimicrobial agents, whereas acidic sophorolipids display better foaming properties. Acetyl groups can also lower the hydrophilicity of sophorolipids and enhance their antiviral and cytokine stimulating effects.
Sophorolipids are produced by various non pathogenic yeast species such as Candida apicola, Rhodotorula bogoriensis, Wickerhamiella domercqiae, and Starmerella bombicola. Recent research has meant sophorolipids can be recovered during a fermentation using a gravity separator in a loop with the bioreactor, enabling the production of >770 g/L sophorolipid at a productivity 4.24 g/L/h, some of the highest values seen in a fermentation process Desirable properties of biosurfactants are biodegradability and low toxicity. Sophorolipids produced by several yeasts belonging to candida and the starmerella clade, and Rhamnolipid produced by Pseudomonas aeruginosa etc.
Besides biodegradability, low toxicity, and high production potential, sophorolipids have a high surface and interfacial activity. Sophorolipids are reported to lower surface tension (ST) of water from 72 to 30-35 mN/m and the interfacial tension (IT) water/hexadecane from 40 to 1 mN/m. In addition to this, sophorolipids are reported to function under wide ranges of temperatures, pressures and ionic strengths; and they also possess a number of other useful biological activities including Antimicrobial, virucidal, Anticancer, Immuno-modulatory properties. | 0 | Theoretical and Fundamental Chemistry |
Diatoms can also be used to study oxygen isotopes and are especially useful in regions of the ocean where foraminifera do not preserve in marine sediments. One example of vital effects in diatoms is a difference in δO between two different species, Coscinodiscus marginatus and Coscinodiscus radiatus, which is attributed to their difference in size. | 0 | Theoretical and Fundamental Chemistry |
In Runyon et al. 2006, the researchers demonstrate how the parasitic plant, Cuscuta pentagona (field dodder), uses VOCs to interact with various hosts and determine locations. Dodder seedlings show direct growth toward tomato plants (Lycopersicon esculentum) and, specifically, tomato plant volatile organic compounds. This was tested by growing a dodder weed seedling in a contained environment, connected to two different chambers. One chamber contained tomato VOCs while the other had artificial tomato plants. After 4 days of growth, the dodder weed seedling showed a significant growth towards the direction of the chamber with tomato VOCs. Their experiments also showed that the dodder weed seedlings could distinguish between wheat (Triticum aestivum) VOCs and tomato plant volatiles. As when one chamber was filled with each of the two different VOCs, dodder weeds grew towards tomato plants as one of the wheat VOCs is repellent. These findings show evidence that volatile organic compounds determine ecological interactions between plant species and show statistical significance that the dodder weed can distinguish between different plant species by sensing their VOCs.
Tomato plant to plant communication is further examined in Zebelo et al. 2012, which studies tomato plant response to herbivory. Upon herbivory by Spodoptera littoralis, tomato plants emit VOCs that are released into the atmosphere and induce responses in neighboring tomato plants. When the herbivory-induced VOCs bind to receptors on other nearby tomato plants, responses occur within seconds. The neighboring plants experience a rapid depolarization in cell potential and increase in cytosolic calcium. Plant receptors are most commonly found on plasma membranes as well as within the cytosol, endoplasmic reticulum, nucleus, and other cellular compartments. VOCs that bind to plant receptors often induce signal amplification by action of secondary messengers including calcium influx as seen in response to neighboring herbivory. These emitted volatiles were measured by GC-MS and the most notable were 2-hexenal and 3-hexenal acetate. It was found that depolarization increased with increasing green leaf volatile concentrations. These results indicate that tomato plants communicate with one another via airborne volatile cues, and when these VOC's are perceived by receptor plants, responses such as depolarization and calcium influx occur within seconds. | 1 | Applied and Interdisciplinary Chemistry |
Admission in M.Sc. through Departmental Entrance Test conducted by Department itself followed by personal interview.
M.Sc. (Chemistry, Applied Chemistry and Pharmaceutical Chemistry)
* Total number of seats for each course: 20
* Course duration: Four Semesters (two years)
* Reservation for various categories will be as per Government Rules.
* Basic qualification: B.Sc. with 65% marks and Chemistry as one of the subjects.
* Admission of candidate with less than 50% marks will not be considered.
Admission in PhD is through DET conducted by Department. Relaxation to those candidates who have qualified NET or GATE examination followed by personal interview. | 1 | Applied and Interdisciplinary Chemistry |
Selenium is an essential micronutrient for animals, though it is toxic in large doses. In plants, it sometimes occurs in toxic amounts as forage, e.g. locoweed. Selenium is a component of the amino acids selenocysteine and selenomethionine. In humans, selenium is a trace element nutrient that functions as cofactor for glutathione peroxidases and certain forms of thioredoxin reductase. Selenium-containing proteins are produced from inorganic selenium via the intermediacy of selenophosphate (PSeO). | 1 | Applied and Interdisciplinary Chemistry |
Catalytic resonance theory is constructed on the Sabatier principle of catalysis developed by French chemistry Paul Sabatier. In the limit of maximum catalytic performance, the surface of a catalyst is neither too strong nor too weak. Strong binding results in an overall catalytic reaction rate limitation due to product desorption, while weak binding catalysts are limited in the rate of surface chemistry. Optimal catalyst performance is depicted as a volcano peak using a descriptor of the chemical reaction defining different catalytic materials. Experimental evidence of the Sabatier principle was first demonstrated by Balandin in 1960.
The concept of catalytic resonance was proposed on dynamic interpretation of the Sabatier volcano reaction plot. As described, extension of either side of the volcano plot above the peak defines the timescales of the two rate-limiting phenomena such as surface reaction(s) or desorption. For binding energy oscillation amplitudes that extend across the volcano peak, the amplitude endpoints intersect the transiently accessible faster timescales of independent reaction phenomena. At the conditions of sufficiently fast binding energy oscillation, the transient binding energy variation frequency matches the natural frequencies of the reaction and the rate of overall reaction achieves turnover frequencies greatly in excess of the volcano plot peak. | 0 | Theoretical and Fundamental Chemistry |
In ionic bonding, the atoms are bound by attraction of oppositely charged ions, whereas, in covalent bonding, atoms are bound by sharing electrons to attain stable electron configurations. In covalent bonding, the molecular geometry around each atom is determined by valence shell electron pair repulsion VSEPR rules, whereas, in ionic materials, the geometry follows maximum packing rules. One could say that covalent bonding is more directional in the sense that the energy penalty for not adhering to the optimum bond angles is large, whereas ionic bonding has no such penalty. There are no shared electron pairs to repel each other, the ions should simply be packed as efficiently as possible. This often leads to much higher coordination numbers. In NaCl, each ion has 6 bonds and all bond angles are 90°. In CsCl the coordination number is 8. By comparison carbon typically has a maximum of four bonds.
Purely ionic bonding cannot exist, as the proximity of the entities involved in the bonding allows some degree of sharing electron density between them. Therefore, all ionic bonding has some covalent character. Thus, bonding is considered ionic where the ionic character is greater than the covalent character. The larger the difference in electronegativity between the two types of atoms involved in the bonding, the more ionic (polar) it is. Bonds with partially ionic and partially covalent character are called polar covalent bonds. For example, Na–Cl and Mg–O interactions have a few percent covalency, while Si–O bonds are usually ~50% ionic and ~50% covalent. Pauling estimated that an electronegativity difference of 1.7 (on the Pauling scale) corresponds to 50% ionic character, so that a difference greater than 1.7 corresponds to a bond which is predominantly ionic.
Ionic character in covalent bonds can be directly measured for atoms having quadrupolar nuclei (H, N, Br, Cl or I). These nuclei are generally objects of NQR nuclear quadrupole resonance and NMR nuclear magnetic resonance studies. Interactions between the nuclear quadrupole moments Q and the electric field gradients (EFG) are characterized via the nuclear quadrupole coupling constants
:QCC =
where the eq term corresponds to the principal component of the EFG tensor and e is the elementary charge. In turn, the electric field gradient opens the way to description of bonding modes in molecules when the QCC values are accurately determined by NMR or NQR methods.
In general, when ionic bonding occurs in the solid (or liquid) state, it is not possible to talk about a single "ionic bond" between two individual atoms, because the cohesive forces that keep the lattice together are of a more collective nature. This is quite different in the case of covalent bonding, where we can often speak of a distinct bond localized between two particular atoms. However, even if ionic bonding is combined with some covalency, the result is not necessarily discrete bonds of a localized character. In such cases, the resulting bonding often requires description in terms of a band structure consisting of gigantic molecular orbitals spanning the entire crystal. Thus, the bonding in the solid often retains its collective rather than localized nature. When the difference in electronegativity is decreased, the bonding may then lead to a semiconductor, a semimetal or eventually a metallic conductor with metallic bonding. | 0 | Theoretical and Fundamental Chemistry |
Conductive metal−organic frameworks are a class of metal–organic frameworks with intrinsic ability of electronic conduction. Metal ions and organic linker self-assemble to form a framework which can be 1D/2D/3D in connectivity. The first conductive MOF, Cu[Cu(2,3-pyrazinedithiol)] was described in 2009 and exhibited electrical conductivity of 6 × 10 S cm at 300 K. | 0 | Theoretical and Fundamental Chemistry |
Mechanically stimulated gas emission (MSGE) is a complex phenomenon embracing various physical and chemical processes occurring on the surface and in the bulk of a solid under applied mechanical stress and resulting in emission of gases. MSGE is a part of a more general phenomenon of mechanically stimulated neutral emission. MSGE experiments are often performed in ultra-high vacuum. | 0 | Theoretical and Fundamental Chemistry |
In England and Wales acceptable levels for drinking water supply are listed in the "Water Supply (Water Quality) Regulations 2000." | 0 | Theoretical and Fundamental Chemistry |
The FSP is used when metals properties want to be improved using other metals for support and improvement of the first. This is promising process for the automotive and aerospace industries where new material will need to be developed to improve resistance to wear, creep, and fatigue. (Misha) Examples of materials successfully processed using the friction stir technique include AA 2519, AA 5083 and AA 7075 aluminum alloys, AZ61 magnesium alloy, nickel-aluminium bronze and 304L stainless steel. | 1 | Applied and Interdisciplinary Chemistry |
*MCM3AP possibly a primase
*XRCC5 NM_021141 Ku80
*XRCC6 NM_001469 Homo sapiens thyroid autoantigen: Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. | 1 | Applied and Interdisciplinary Chemistry |
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