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kidney development negative regulation of retinoic acid receptor signaling pathway response to retinoic acid response to vitamin A retinoic acid catabolic process retinoic acid metabolic process sterol metabolic process vitamin metabolic process xenobiotic metabolic process |
brain development G1 to G0 transition gamma-aminobutyric acid metabolic process glial cell development glutamine metabolic process glycine metabolic process L-serine biosynthetic process neural tube development neuron projection development regulation of gene expression spinal cord development taurine metabolic process threonine metabolic process |
actin filament polymerization activation of phospholipase C activity focal adhesion assembly negative regulation of focal adhesion assembly negative regulation of stress fiber assembly positive regulation of phospholipase activity regulation of small GTPase mediated signal transduction Rho protein signal transduction |
cell adhesion myoblast fusion positive regulation of angiogenesis proteolysis |
animal organ morphogenesis cell differentiation nervous system development positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to stimulus visual perception |
canonical NF-kappaB signal transduction cellular response to lipopolysaccharide inflammatory response interleukin-1-mediated signaling pathway intracellular signal transduction lipopolysaccharide-mediated signaling pathway MyD88-dependent toll-like receptor signaling pathway negative regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity protein phosphorylation regulation of cytokine-mediated signaling pathway response to interleukin-1 Toll signaling pathway toll-like receptor 4 signaling pathway |
chromatin organization DNA repair-dependent chromatin remodeling regulation of DNA-templated transcription |
G protein-coupled receptor signaling pathway |
G protein-coupled receptor signaling pathway |
chiasma assembly mismatch repair |
apoptotic process cytoskeleton-dependent cytokinesis flagellated sperm motility hematopoietic stem cell homeostasis neuron migration positive regulation of apoptotic process positive regulation of intrinsic apoptotic signaling pathway positive regulation of protein ubiquitination regulation of apoptotic process regulation of exocytosis spermatid differentiation |
cellular response to nerve growth factor stimulus centrosome localization microtubule cytoskeleton organization microtubule-based movement |
cell cycle proteolysis |
proteasome-mediated ubiquitin-dependent protein catabolic process regulation of protein catabolic process ubiquitin-dependent protein catabolic process |
anatomical structure development anterior/posterior pattern specification embryonic digit morphogenesis embryonic skeletal joint morphogenesis endoderm development metanephros development organ induction positive regulation of transcription by RNA polymerase II proximal/distal pattern formation regulation of transcription by RNA polymerase II |
intracellular estrogen receptor signaling pathway mRNA processing negative regulation of DNA-templated transcription nervous system development regulation of alternative mRNA splicing, via spliceosome regulation of cell population proliferation RNA metabolic process RNA splicing |
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process phosphorylation skeletal system development sulfate assimilation |
amyloid fibril formation apoptotic process canonical Wnt signaling pathway cell cycle negative regulation of apoptotic process negative regulation of canonical Wnt signaling pathway negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of extrinsic apoptotic signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination regulation of circadian rhythm regulation of protein ubiquitination rhythmic process small GTPase mediated signal transduction ubiquitin-dependent protein catabolic process |
calcium ion homeostasis chromatin remodeling heart process intestinal stem cell homeostasis muscle cell differentiation positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator positive regulation of lymphoid progenitor cell differentiation positive regulation of transcription initiation by RNA polymerase II regulation of DNA-templated transcription |
cell division endoplasmic reticulum to Golgi vesicle-mediated transport establishment of mitotic spindle orientation Golgi organization meiotic cell cycle mitotic metaphase chromosome alignment mitotic sister chromatid segregation mitotic spindle assembly checkpoint signaling protein localization to kinetochore protein transport protein-containing complex assembly regulation of attachment of spindle microtubules to kinetochore regulation of exit from mitosis retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
4-hydroxyproline catabolic process intrinsic apoptotic signaling pathway in response to oxidative stress proline catabolic process proline catabolic process to glutamate proline metabolic process regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway |
branching involved in labyrinthine layer morphogenesis cellular response to BMP stimulus epidermis development epithelium development extracellular matrix organization negative regulation of neural precursor cell proliferation neural tube closure placenta blood vessel development positive regulation of glial cell differentiation |
animal organ morphogenesis trehalose catabolic process trehalose metabolic process |
cell adhesion cell migration intracellular signal transduction transmembrane receptor protein tyrosine kinase signaling pathway |
JNK cascade peptidyl-serine phosphorylation positive regulation of axon extension positive regulation of branching morphogenesis of a nerve positive regulation of JUN kinase activity positive regulation of neuron maturation positive regulation of neuron projection arborization positive regulation of NF-kappaB transcription factor activity protein autophosphorylation protein phosphorylation stress-activated MAPK cascade |
carbohydrate metabolic process central nervous system myelination central nervous system neuron axonogenesis ganglioside biosynthetic process via lactosylceramide glycoprotein biosynthetic process glycosylation neuron maturation O-glycan processing poly-N-acetyllactosamine biosynthetic process positive regulation of embryonic development protein glycosylation regulation of protein stability |
maturation of 5S rRNA mRNA cis splicing, via spliceosome mRNA splicing, via spliceosome positive regulation of cytotoxic T cell differentiation spliceosomal snRNP assembly |
basement membrane organization cellular response to BMP stimulus epithelial cell morphogenesis involved in placental branching establishment or maintenance of cell polarity negative regulation of cell motility negative regulation of cell-cell adhesion negative regulation of neural precursor cell proliferation neural tube closure |
attachment of GPI anchor to protein protein retention in ER lumen protein-containing complex assembly |
apoptotic process apoptotic signaling pathway cellular response to type II interferon chromatin organization intracellular signal transduction negative regulation of translation positive regulation of apoptotic process positive regulation of canonical Wnt signaling pathway positive regulation of cell migration protein autophosphorylation protein phosphorylation regulation of actin cytoskeleton organization regulation of apoptotic process regulation of autophagy regulation of cell motility regulation of cell shape regulation of DNA-templated transcription regulation of focal adhesion assembly regulation of mitotic cell cycle regulation of mitotic nuclear division regulation of myosin II filament organization regulation of smooth muscle contraction |
cell adhesion cell fate commitment epithelial cell differentiation fat cell differentiation morphogenesis of embryonic epithelium negative regulation of cell population proliferation negative regulation of fat cell differentiation positive regulation of DNA-templated transcription positive regulation of epithelial to mesenchymal transition positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of ubiquitin-dependent protein catabolic process Wnt signaling pathway |
regulation of transcription by RNA polymerase II |
regulation of transcription by RNA polymerase II |
long-term synaptic potentiation negative regulation of receptor internalization positive regulation of synapse assembly regulation of postsynaptic density assembly synapse organization |
regulation of postsynaptic specialization assembly regulation of small GTPase mediated signal transduction |
regulation of transcription by RNA polymerase II |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay regulation of translational initiation |
actin cytoskeleton organization adherens junction maintenance cell adhesion cellular response to fluid shear stress epithelial cell proliferation involved in renal tubule morphogenesis glomerulus morphogenesis microspike assembly negative regulation of epithelial cell proliferation nephron tubule epithelial cell differentiation plasma membrane organization positive regulation of actin filament bundle assembly renal tubule morphogenesis transmembrane receptor protein tyrosine kinase signaling pathway |
DNA damage response motile cilium assembly positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of non-motile cilium assembly positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II |
amine transport canalicular bile acid transport cellular response to cAMP glycerol transmembrane transport purine nucleobase transport pyrimidine nucleobase transport response to pain urea transmembrane transport water transport |
anatomical structure development animal organ morphogenesis cell differentiation regulation of transcription by RNA polymerase II |
animal organ morphogenesis cell differentiation cell-cell signaling fibroblast growth factor receptor signaling pathway positive regulation of cell population proliferation positive regulation of endothelial cell chemotaxis to fibroblast growth factor positive regulation of gene expression positive regulation of protein phosphorylation response to temperature stimulus signal transduction |
cell fate specification cell-cell signaling Leydig cell differentiation male sex determination myelination osteoblast differentiation positive regulation of smoothened signaling pathway protein autoprocessing regulation of gene expression regulation of steroid biosynthetic process response to estradiol response to estrogen self proteolysis smoothened signaling pathway spermatid development |
anterior/posterior pattern specification brain segmentation cell fate determination cellular response to retinoic acid dorsal/ventral pattern formation embryonic viscerocranium morphogenesis middle ear morphogenesis motor neuron axon guidance muscle structure development negative regulation of neuron differentiation negative regulation of osteoblast differentiation osteoblast development pharyngeal system development positive regulation of transcription by RNA polymerase II rhombomere 2 development rhombomere 3 morphogenesis segment specification |
angiogenesis animal organ formation anterior/posterior pattern specification blood vessel remodeling cartilage development embryonic skeletal system morphogenesis gene expression glossopharyngeal nerve morphogenesis parathyroid gland development positive regulation of stem cell proliferation regulation of transcription by RNA polymerase II specification of animal organ position stem cell proliferation thymus development thyroid gland development |
cellular response to calcium ion intracellular signal transduction negative regulation of GTPase activity negative regulation of Ras protein signal transduction |
mRNA processing mRNA splicing, via spliceosome |
mRNA processing mRNA splicing, via spliceosome RNA splicing RNA splicing, via transesterification reactions spliceosomal tri-snRNP complex assembly |
carbohydrate metabolic process regulation of cell population proliferation |
regulation of cell shape sensory perception of sound |
cerebellar granule cell differentiation excitatory postsynaptic potential excitatory synapse assembly glutamate receptor signaling pathway heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules modulation of chemical synaptic transmission positive regulation of long-term synaptic depression positive regulation of synapse assembly prepulse inhibition protein localization regulation of neuron apoptotic process regulation of neuron projection development regulation of postsynaptic density assembly regulation of presynapse assembly synaptic transmission, glutamatergic |
fibroblast growth factor receptor signaling pathway platelet aggregation |
DNA-templated transcription intestinal epithelial cell differentiation negative regulation of DNA-templated transcription negative regulation of neuron projection development negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of neuron projection development |
mRNA splicing, via spliceosome positive regulation of viral genome replication protein folding protein peptidyl-prolyl isomerization protein-containing complex assembly |
potassium ion transport regulation of potassium ion transmembrane transport |
ATF6-mediated unfolded protein response bone maturation cholesterol metabolic process endoplasmic reticulum unfolded protein response membrane protein intracellular domain proteolysis mitotic G2 DNA damage checkpoint signaling positive regulation of transcription by RNA polymerase II protein maturation regulation of cholesterol biosynthetic process regulation of response to endoplasmic reticulum stress response to endoplasmic reticulum stress |
cell cycle cell differentiation cellular response to glucose starvation cellular response to hypoxia chromatin organization circadian rhythm DNA damage response energy homeostasis epigenetic programming in the zygotic pronuclei methylation negative regulation of cell cycle negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of histone deacetylation rDNA heterochromatin formation regulation of transcription by glucose rRNA processing |
cell communication cell division CENP-A containing chromatin assembly chromosome segregation |
carbohydrate metabolic process cellular aldehyde metabolic process daunorubicin metabolic process doxorubicin metabolic process lipid metabolic process |
camera-type eye photoreceptor cell differentiation glomerular parietal epithelial cell differentiation photoreceptor cell maintenance podocyte differentiation positive regulation of nephron tubule epithelial cell differentiation retina layer formation retina morphogenesis in camera-type eye |
actomyosin structure organization cell cycle cell division cortical actin cytoskeleton organization positive regulation of protein localization to cell cortex |
DNA recombination DNA repair double-strand break repair via homologous recombination female meiosis sister chromatid cohesion male meiosis I meiotic DNA recombinase assembly positive regulation of G2/M transition of mitotic cell cycle reciprocal meiotic recombination sister chromatid cohesion spermatogenesis telomere maintenance via recombination |
axon guidance keratan sulfate biosynthetic process protein O-linked mannosylation |
male gonad development proteolysis single fertilization |
angiogenesis apoptotic process cell differentiation endothelial cell migration extrinsic apoptotic signaling pathway immune response positive regulation of angiogenesis positive regulation of endothelial cell proliferation positive regulation of extrinsic apoptotic signaling pathway positive regulation of protein catabolic process signal transduction |
inorganic anion transport iodide transport monoatomic ion transport regulation of pH regulation of protein localization sensory perception of sound sulfate transport |
positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II protein ubiquitination regulation of transcription by RNA polymerase II RNA polymerase II preinitiation complex assembly somatic stem cell population maintenance transcription initiation at RNA polymerase II promoter |
actin filament-based movement actin polymerization or depolymerization protein-containing complex assembly response to other organism |
action potential initiation apoptosome assembly cellular response to calcium ion cellular response to xenobiotic stimulus chemical synaptic transmission endocytosis excitatory chemical synaptic transmission exocytosis gene expression inhibitory chemical synaptic transmission membrane hyperpolarization mitochondrial depolarization nerve development neuron apoptotic process neuron remodeling neuronal action potential potassium ion transmembrane transport protein import into nucleus protein targeting psychomotor behavior regulation of action potential firing threshold regulation of synaptic plasticity response to auditory stimulus response to organic cyclic compound sensory perception of sound substantia propria of cornea development |
chemical synaptic transmission nervous system development potassium ion transmembrane transport |
androgen metabolic process carbohydrate biosynthetic process cell adhesion estrogen metabolic process learning long-term memory proteoglycan biosynthetic process |
DNA damage response DNA recombination DNA repair double-strand break repair via homologous recombination double-strand break repair via synthesis-dependent strand annealing interstrand cross-link repair positive regulation of mitotic cell cycle spindle assembly checkpoint regulation of centrosome duplication resolution of mitotic recombination intermediates response to organic substance t-circle formation telomere maintenance via recombination telomere maintenance via telomere trimming telomeric loop disassembly |
centrosome cycle DNA repair DNA strand invasion double-strand break repair via homologous recombination in utero embryonic development meiotic cell cycle mitotic cell cycle multicellular organism growth negative regulation of neuron apoptotic process neurogenesis positive regulation of neurogenesis regulation of fibroblast apoptotic process response to gamma radiation response to X-ray somitogenesis |
epidermis development protein modification process |
apoptotic process cellular response to mechanical stimulus immune response positive regulation of myoblast differentiation positive regulation of myoblast fusion positive regulation of non-canonical NF-kappaB signal transduction positive regulation of T cell chemotaxis signal transduction T cell activation T cell chemotaxis T cell costimulation T cell homeostasis T cell proliferation |
fibroblast growth factor receptor signaling pathway signal transduction |
adaptive immune response calcium-mediated signaling gene expression immune response inflammatory response integrin-mediated signaling pathway intracellular signal transduction lymphocyte homeostasis mast cell degranulation positive regulation of protein kinase activity Ras protein signal transduction regulation of T cell activation T cell activation T cell receptor signaling pathway |
cell division chromosome segregation G protein-coupled receptor signaling pathway learning long-term memory long-term synaptic potentiation mitotic cell cycle negative regulation of ERK1 and ERK2 cascade negative regulation of G protein-coupled receptor signaling pathway negative regulation of MAP kinase activity negative regulation of synaptic plasticity nucleocytoplasmic transport platelet-derived growth factor receptor signaling pathway positive regulation of neurogenesis regulation of G protein-coupled receptor signaling pathway response to oxidative stress spindle organization visual learning zygote asymmetric cell division |
organelle localization positive regulation of stress-activated protein kinase signaling cascade protein autoubiquitination ubiquitin-dependent protein catabolic process |
chloride ion homeostasis estrous cycle one-carbon metabolic process |
protein localization signal transduction |
calcium ion regulated lysosome exocytosis calcium ion-regulated exocytosis of neurotransmitter cellular response to calcium ion phagocytosis phagosome-lysosome fusion plasma membrane repair positive regulation of calcium ion-dependent exocytosis regulation of bone remodeling regulation of calcium ion-dependent exocytosis regulation of dopamine secretion regulation of glucagon secretion regulation of insulin secretion regulation of phagocytosis regulation of synaptic vesicle endocytosis short-term synaptic potentiation synaptic vesicle recycling vesicle fusion vesicle-mediated cholesterol transport |
actin filament polymerization cell adhesion endocytosis inflammatory response innate immune response signal transduction |
intracellular protein transport tRNA export from nucleus tRNA re-export from nucleus |
deoxyribonucleoside monophosphate catabolic process epithelial cell differentiation nucleoside salvage positive regulation of cell growth purine nucleotide catabolic process |
axoneme assembly central nervous system development intracellular signal transduction nervous system development neuron migration retina development in camera-type eye |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell surface receptor signaling pathway feeding behavior galanin-activated signaling pathway inositol phosphate metabolic process learning or memory muscle contraction neuron projection development neuropeptide signaling pathway phosphatidylinositol metabolic process phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of large conductance calcium-activated potassium channel activity positive regulation of transcription by RNA polymerase II |
chemical synaptic transmission eating behavior excitatory postsynaptic potential negative regulation of DNA replication negative regulation of potassium ion transport negative regulation of transmission of nerve impulse neuropeptide signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of calcium ion transport positive regulation of cold-induced thermogenesis positive regulation of cytosolic calcium ion concentration positive regulation of transmission of nerve impulse protein kinase C-activating G protein-coupled receptor signaling pathway regulation of neurotransmitter secretion response to starvation sleep temperature homeostasis |
cellular response to hormone stimulus chemical synaptic transmission feeding behavior neuropeptide signaling pathway positive regulation of ERK1 and ERK2 cascade regulation of cytosolic calcium ion concentration |
cellular response to hormone stimulus chemical synaptic transmission circadian sleep/wake cycle process feeding behavior locomotion neuropeptide signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway regulation of circadian sleep/wake cycle, wakefulness regulation of cytosolic calcium ion concentration |
intracellular protein transport protein import into mitochondrial matrix protein targeting to mitochondrion |
autophagosome maturation autophagy endosome transport via multivesicular body sorting pathway ESCRT III complex disassembly establishment of protein localization exit from mitosis late endosome to lysosome transport late endosome to vacuole transport macroautophagy membrane fission membrane invagination midbody abscission mitotic metaphase chromosome alignment multivesicular body assembly multivesicular body sorting pathway multivesicular body-lysosome fusion negative regulation of centriole elongation nuclear membrane reassembly nucleus organization plasma membrane repair positive regulation of exosomal secretion protein homooligomerization protein polymerization protein transport regulation of centrosome duplication regulation of mitotic spindle assembly ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway vesicle fusion with vacuole viral budding from plasma membrane viral budding via host ESCRT complex viral release from host cell |
actin filament organization cell migration dendritic spine development ephrin receptor signaling pathway epidermal growth factor receptor signaling pathway immunological synapse formation lamellipodium assembly negative regulation of cell population proliferation negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation negative regulation of PERK-mediated unfolded protein response negative regulation of transcription by RNA polymerase II positive regulation of actin filament polymerization positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of peptidyl-serine dephosphorylation positive regulation of T cell proliferation positive regulation of transcription by RNA polymerase II positive regulation of translation in response to endoplasmic reticulum stress signal complex assembly signal transduction T cell activation |
negative regulation of ERK1 and ERK2 cascade regulation of neurotransmitter receptor activity |
cell division microtubule cytoskeleton organization mitotic spindle elongation mitotic spindle midzone assembly positive regulation of cell population proliferation regulation of cytokinesis |
G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway negative regulation of signal transduction positive regulation of GTPase activity regulation of G protein-coupled receptor signaling pathway |
attachment of spindle microtubules to kinetochore cell division microtubule bundle formation microtubule polymerization mitotic sister chromatid segregation mitotic spindle assembly mitotic spindle assembly checkpoint signaling protein stabilization regulation of chromosome segregation |
cellular component biogenesis epithelial structure maintenance hair follicle development negative regulation of transcription by RNA polymerase II nervous system development positive regulation of cellular component biogenesis positive regulation of transcription by RNA polymerase II regulation of cell migration regulation of kinase activity somatic stem cell population maintenance |
branching involved in ureteric bud morphogenesis branchiomeric skeletal muscle development bronchiole development developmental process diaphragm development embryonic digestive tract morphogenesis epithelial cell differentiation gland development glomerulus development kidney development lung alveolus development lung morphogenesis lung vasculature development metanephric glomerular capillary formation metanephric mesenchymal cell differentiation morphogenesis of a branching structure negative regulation of androgen receptor signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II reproductive structure development respiratory system development roof of mouth development Sertoli cell differentiation sex determination spleen development ureteric bud development vasculature development |
post-translational protein targeting to endoplasmic reticulum membrane protein insertion into ER membrane tail-anchored membrane protein insertion into ER membrane |
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