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heme catabolic process heme oxidation response to hypoxia response to oxidative stress |
endosome to lysosome transport intracellular protein transport organelle assembly organelle localization positive regulation of receptor localization to synapse positive regulation of T cell mediated cytotoxicity regulation of protein localization to plasma membrane synaptic vesicle exocytosis vesicle docking vesicle fusion vesicle-mediated transport |
negative regulation of DNA-templated transcription negative regulation of gene expression negative regulation of osteoclast differentiation negative regulation of protein sumoylation negative regulation of transcription by RNA polymerase II positive regulation of gene expression positive regulation of membrane potential positive regulation of protein sumoylation protein sumoylation regulation of transcription by RNA polymerase II response to hormone TNFSF11-mediated signaling pathway |
protein ubiquitination ubiquitin-dependent protein catabolic process |
dephosphorylation |
camera-type eye development circadian rhythm detection of light stimulus involved in visual perception neural retina development response to light stimulus retina homeostasis retinal metabolic process retinoid metabolic process retinol metabolic process zeaxanthin biosynthetic process |
negative regulation of translation positive regulation of toll-like receptor 3 signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein K63-linked ubiquitination protein polyubiquitination protein transport protein ubiquitination regulation protein catabolic process at postsynapse |
peptidyl-tyrosine sulfation |
animal organ morphogenesis canonical Wnt signaling pathway cell fate commitment cell-cell signaling cellular response to starvation chondrocyte differentiation forebrain regionalization hematopoietic stem cell proliferation lung induction male gonad development mesenchymal-epithelial cell signaling neuron differentiation positive regulation of branching involved in ureteric bud morphogenesis signal transduction |
desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor internalization phosphorylation receptor internalization regulation of signal transduction signal transduction |
desensitization of G protein-coupled receptor signaling pathway phosphorylation regulation of signal transduction Wnt signaling pathway |
camera-type eye development cell population proliferation eye development positive regulation of cell population proliferation |
apoptotic process cellular response to cold lipid droplet fusion lipid metabolic process lipid storage negative regulation of cold-induced thermogenesis negative regulation of cytokine production negative regulation of execution phase of apoptosis negative regulation of lipid catabolic process negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of tumor necrosis factor production positive regulation of sequestering of triglyceride regulation of apoptotic DNA fragmentation regulation of apoptotic process response to stilbenoid temperature homeostasis |
apoptotic process COPII-coated vesicle cargo loading execution phase of apoptosis lipid droplet fusion lipid storage positive regulation of apoptotic process regulation of apoptotic process regulation of triglyceride metabolic process very-low-density lipoprotein particle assembly |
cell fate specification embryonic cranial skeleton morphogenesis embryonic skeletal system morphogenesis negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II |
cell migration cell-matrix adhesion epithelial cell-cell adhesion integrin-mediated signaling pathway stress fiber assembly transforming growth factor beta receptor signaling pathway |
cellular ketone metabolic process in utero embryonic development N-terminal peptidyl-glycine N-myristoylation protein localization to membrane |
actin cytoskeleton organization actomyosin structure organization cell cycle cell division cortical actin cytoskeleton organization positive regulation of protein localization to cell cortex regulation of cell shape |
amino acid import across plasma membrane amino acid metabolic process hormone transport negative regulation of neural precursor cell proliferation thyroid hormone generation thyroid hormone metabolic process thyroid hormone transport thyroid-stimulating hormone secretion transport across blood-brain barrier |
arachidonic acid metabolic process chromatin organization lipoxygenase pathway negative regulation of ferroptosis protein polymerization response to estradiol response to oxidative stress spermatogenesis |
cytoplasmic microtubule organization establishment of protein localization mRNA processing protein localization to microtubule regulation of postsynaptic density assembly regulation of postsynaptic density protein 95 clustering RNA splicing |
apoptotic mitochondrial changes male gonad development positive regulation of protein-containing complex assembly positive regulation of release of cytochrome c from mitochondria regulation of apoptotic process spermatogenesis |
cardiac left ventricle morphogenesis chemical synaptic transmission eating behavior G protein-coupled receptor signaling pathway generation of ovulation cycle rhythm negative regulation of acute inflammatory response to antigenic stimulus negative regulation of apoptotic process negative regulation of glutamate secretion negative regulation of synaptic transmission, GABAergic outflow tract morphogenesis positive regulation of acute inflammatory response positive regulation of cell population proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of smooth muscle cell proliferation synaptic signaling via neuropeptide |
mRNA catabolic process NAD-cap decapping nuclear mRNA surveillance nuclear-transcribed mRNA catabolic process nucleic acid metabolic process RNA destabilization |
androgen metabolic process bile acid biosynthetic process brexanolone metabolic process C21-steroid hormone metabolic process estrogen metabolic process fatty acid beta-oxidation fatty acid metabolic process isoleucine catabolic process Leydig cell differentiation male gonad development mitochondrial tRNA 3'-end processing mitochondrial tRNA 5'-end processing mitochondrial tRNA methylation mitochondrion organization protein homotetramerization |
negative regulation of T cell receptor signaling pathway positive regulation of interleukin-2 production positive regulation of T cell proliferation regulation of cytokine production T cell receptor signaling pathway |
antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen basement membrane disassembly bone resorption collagen catabolic process immune response positive regulation of apoptotic signaling pathway positive regulation of cation channel activity positive regulation of inflammatory response protein processing proteolysis proteolysis involved in protein catabolic process response to acidic pH |
DNA-templated transcription epithelial cell differentiation intestinal epithelial cell differentiation negative regulation of DNA-templated transcription negative regulation of neuron projection development negative regulation of Notch signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of neuron projection development |
exocytic insertion of neurotransmitter receptor to postsynaptic membrane exocytosis histamine secretion by mast cell membrane fusion protein-containing complex assembly regulation of exocytosis synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle priming vesicle-mediated transport vesicle-mediated transport in synapse |
cytokine-mediated signaling pathway defense response to Gram-positive bacterium negative regulation of cellular extravasation negative regulation of interleukin-17 production negative regulation of interleukin-6 production negative regulation of neuron apoptotic process negative regulation of T cell extravasation negative regulation of T-helper 17 type immune response negative regulation of tumor necrosis factor production negative regulation of type 2 immune response positive regulation of T-helper 1 type immune response positive regulation of type II interferon production regulation of isotype switching to IgG isotypes |
actin cytoskeleton organization establishment or maintenance of actin cytoskeleton polarity fibroblast migration heart development maintenance of cell polarity muscle structure development regulation of transcription by RNA polymerase II response to hypoxia stress fiber assembly |
autophagosome maturation autophagosome membrane docking cellular response to type II interferon defense response to virus establishment of localization in cell membrane fusion mucus secretion negative regulation of secretion by cell positive regulation of histamine secretion by mast cell positive regulation of pancreatic amylase secretion protein transport protein-containing complex assembly regulation of endocytosis regulation of protein localization to plasma membrane SNARE complex assembly vesicle fusion vesicle-mediated transport viral entry into host cell zymogen granule exocytosis |
embryonic brain development endoplasmic reticulum organization G1 to G0 transition involved in cell differentiation neuron differentiation positive regulation of glial cell differentiation positive regulation of neuron differentiation protein autoubiquitination protein homooligomerization regulation of cell cycle response to hydroperoxide |
atrial cardiac muscle cell development heart trabecula formation negative regulation of apoptotic process negative regulation of calcineurin-NFAT signaling cascade negative regulation of transcription by RNA polymerase II osteoblast differentiation regulation of transcription by RNA polymerase II response to hormone ventricular cardiac muscle cell development |
proteasomal protein catabolic process ubiquitin-dependent protein catabolic process |
endosome to lysosome transport intracellular protein transport organelle assembly organelle localization positive regulation of receptor localization to synapse positive regulation of T cell mediated cytotoxicity regulation of protein localization to plasma membrane vesicle docking vesicle fusion vesicle-mediated transport |
neurotransmitter secretion synaptic vesicle clustering synaptic vesicle cycle |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled serotonin receptor signaling pathway negative regulation of insulin secretion |
apoptotic process cell cycle cellular response to forskolin negative regulation of apoptotic process negative regulation of insulin secretion involved in cellular response to glucose stimulus protein phosphorylation regulation of mitotic cell cycle |
cellular response to ionizing radiation DNA damage response DNA repair DNA strand resection involved in replication fork processing homologous recombination mitotic G2/M transition checkpoint negative regulation of apoptotic process negative regulation of protein export from nucleus positive regulation of apoptotic process positive regulation of cell cycle protein K6-linked ubiquitination protein polyubiquitination regulation of DNA damage checkpoint regulation of DNA repair regulation of phosphorylation |
lactate transmembrane transport monocarboxylic acid transport plasma membrane lactate transport pyruvate transmembrane transport |
establishment of skin barrier intrinsic apoptotic signaling pathway in response to DNA damage keratinization keratinocyte development keratinocyte differentiation keratinocyte proliferation negative regulation of innate immune response negative regulation of keratinocyte proliferation negative regulation of stem cell proliferation negative regulation of transcription by RNA polymerase II positive regulation of cell growth positive regulation of epidermal cell differentiation positive regulation of protein export from nucleus protein export from nucleus protein kinase A signaling regulation of cell cycle regulation of epidermal cell division release of cytochrome c from mitochondria signal transduction skin development stem cell proliferation |
cell surface receptor signaling pathway cytokine-mediated signaling pathway oncostatin-M-mediated signaling pathway positive regulation of cell population proliferation response to cytokine |
dendritic spine morphogenesis methylation negative regulation of protein ubiquitination negative regulation of retinoic acid biosynthetic process |
negative regulation of MAPK cascade positive regulation of MAPK cascade Ras protein signal transduction transmembrane receptor protein tyrosine kinase signaling pathway |
aldehyde catabolic process cellular detoxification of aldehyde D-glucuronate catabolic process daunorubicin metabolic process doxorubicin metabolic process glucuronate catabolic process to xylulose 5-phosphate L-ascorbic acid biosynthetic process lipid metabolic process |
carbohydrate metabolic process chondroitin sulfate biosynthetic process gastrulation with mouth forming second glycosaminoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process neuron development protein hexamerization UDP-glucuronate biosynthetic process |
angiogenesis camera-type eye development erythrocyte differentiation hemopoiesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II T cell differentiation |
acyl-CoA metabolic process fatty acid biosynthetic process medium-chain fatty-acyl-CoA metabolic process |
endocytic recycling heme biosynthetic process hemoglobin biosynthetic process intralumenal vesicle formation late endosome to Golgi transport membrane invagination negative regulation of early endosome to late endosome transport negative regulation of phagocytosis negative regulation of protein catabolic process negative regulation of protein transport negative regulation of viral entry into host cell positive regulation of neuron projection development protein to membrane docking regulation of intracellular protein transport regulation of protein metabolic process regulation of Wnt signaling pathway response to bacterium transferrin transport |
B cell differentiation definitive hemopoiesis embryonic camera-type eye morphogenesis embryonic placenta development embryonic process involved in female pregnancy embryonic skeletal system development enucleate erythrocyte differentiation erythrocyte differentiation granulocyte differentiation in utero embryonic development liver development lung development megakaryocyte differentiation monocyte differentiation myeloid progenitor cell differentiation natural killer cell differentiation negative regulation of DNA-templated transcription ossification positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II T cell differentiation trophectodermal cell differentiation |
response to pH transepithelial chloride transport |
cell surface pattern recognition receptor signaling pathway complement activation, lectin pathway G protein-coupled receptor signaling pathway negative regulation of viral entry into host cell positive regulation of interleukin-8 production positive regulation of opsonization protein localization to cell surface proteolysis recognition of apoptotic cell |
estrogen biosynthetic process extracellular matrix organization fatty acid elongation, saturated fatty acid positive regulation of cell-substrate adhesion |
cell-cell signaling fibroblast growth factor receptor signaling pathway myoblast proliferation positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of myoblast proliferation |
negative regulation of signal transduction regulation of G protein-coupled receptor signaling pathway response to ethanol |
dentate gyrus development mRNA destabilization muscle organ development negative regulation of inflammatory response negative regulation of long-term synaptic potentiation negative regulation of translation negative regulation of tumor necrosis factor production non-membrane-bounded organelle assembly nuclear pore complex assembly nuclear pore localization positive regulation of miRNA-mediated gene silencing positive regulation of translation post-transcriptional regulation of gene expression regulation of circadian sleep/wake cycle, sleep regulation of neurogenesis regulation of synaptic transmission, glutamatergic spermatid development |
pexophagy protein import into peroxisome matrix protein import into peroxisome matrix, receptor recycling protein import into peroxisome matrix, substrate release protein import into peroxisome matrix, translocation protein targeting to peroxisome protein tetramerization |
chondrocyte differentiation chondrocyte proliferation ossification sulfate transmembrane transport sulfate transport |
bone mineralization cell differentiation embryonic skeletal system development multicellular organism growth negative regulation of fat cell differentiation negative regulation of Notch signaling pathway negative regulation of vascular endothelial cell proliferation ossification osteoblast differentiation positive regulation of bone resorption positive regulation of cytokine production post-embryonic development regulation of gene expression |
cholesterol efflux cholesterol homeostasis cholesterol metabolic process cholesterol storage macrophage derived foam cell differentiation positive regulation of amyloid precursor protein biosynthetic process very-low-density lipoprotein particle assembly |
adult heart development cardiac muscle cell development cardiac muscle contraction cardiac muscle hypertrophy cardiac muscle hypertrophy in response to stress cardiac muscle tissue morphogenesis cardiac myofibril assembly detection of muscle stretch otic vesicle formation sarcomere organization sarcomerogenesis skeletal muscle contraction skeletal muscle myosin thick filament assembly skeletal muscle thin filament assembly somitogenesis |
cell differentiation chromosome segregation intracellular signal transduction negative regulation of viral genome replication positive regulation of viral genome replication protein phosphorylation regulation of mRNA processing spliceosomal complex assembly |
maternal-to-zygotic transition of gene expression negative regulation of cell population proliferation negative regulation of mitotic cell cycle |
cellular response to fatty acid cellular response to starvation glucose homeostasis insulin receptor signaling pathway negative regulation of anoikis phosphorylation reactive oxygen species metabolic process regulation of acetyl-CoA biosynthetic process from pyruvate regulation of bone resorption regulation of cellular ketone metabolic process regulation of fatty acid biosynthetic process regulation of fatty acid oxidation regulation of glucose metabolic process regulation of pH response to starvation |
ceramide biosynthetic process ceramide metabolic process intracellular signal transduction positive regulation of apoptotic process response to mechanical stimulus sphingolipid catabolic process sphingomyelin catabolic process sphingomyelin metabolic process |
acetylcholine transport amine transport amino acid import across plasma membrane choline transport dopamine transport dopamine uptake epinephrine transport export across plasma membrane histamine transport histamine uptake L-alpha-amino acid transmembrane transport L-arginine import across plasma membrane monoatomic cation transport neurotransmitter transport norepinephrine transport norepinephrine uptake organic cation transport positive regulation of gene expression prostaglandin transport putrescine transport quaternary ammonium group transport serotonin transport serotonin uptake thiamine transmembrane transport toxin transport xenobiotic transport xenobiotic transport across blood-brain barrier |
calcium ion transmembrane transport establishment of localization in cell positive regulation of muscle contraction regulation of calcium ion transmembrane transport via high voltage-gated calcium channel sarcoplasmic reticulum calcium ion transport |
ADP transport AMP transport ATP transport coenzyme A transmembrane transport FAD transmembrane transport fatty acid beta-oxidation fatty acid transport NAD transport |
arachidonic acid metabolic process ceramide biosynthetic process establishment of skin barrier hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxygenase pathway positive regulation of gene expression positive regulation of MAPK cascade positive regulation of mucus secretion protein lipidation sphingolipid metabolic process |
negative regulation of microtubule depolymerization positive regulation of stress-activated MAPK cascade protein localization to microtubule regulation of microtubule cytoskeleton organization |
axonogenesis cell differentiation DNA-templated transcription epithelial cell proliferation lung development negative regulation of epithelial cell proliferation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II respiratory tube development transcription by RNA polymerase II |
neuron differentiation synaptic signaling |
calcium ion import establishment of localization in cell negative regulation of cell-matrix adhesion negative regulation of cellular response to growth factor stimulus negative regulation of keratinocyte proliferation negative regulation of wound healing phosphorylation positive regulation of calcium ion import positive regulation of dendritic spine morphogenesis positive regulation of insulin secretion positive regulation of transcription by RNA polymerase II protein localization to plasma membrane regulation of neurotransmitter secretion regulation of synaptic vesicle exocytosis regulation of transcription by RNA polymerase II |
chaperone-mediated protein folding negative regulation of ER-associated ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-dependent protein catabolic process positive regulation of ER-associated ubiquitin-dependent protein catabolic process post-translational protein targeting to endoplasmic reticulum membrane protein heterooligomerization protein homooligomerization tail-anchored membrane protein insertion into ER membrane ubiquitin-dependent ERAD pathway |
(R)-carnitine transmembrane transport (R)-carnitine transport adult heart development carnitine metabolic process carnitine transport establishment of localization in cell locomotory behavior mitochondrion organization positive regulation of intestinal epithelial structure maintenance quaternary ammonium group transport reproductive structure development response to tumor necrosis factor response to type II interferon sodium ion transport sodium-dependent organic cation transport transport across blood-brain barrier |
brain development cellular detoxification of cadmium ion heme metabolic process heme transmembrane transport heme transport intracellular copper ion homeostasis melanosome assembly porphyrin-containing compound biosynthetic process porphyrin-containing compound metabolic process skin development tetrapyrrole metabolic process transmembrane transport |
brown fat cell differentiation peroxisome fission peroxisome membrane biogenesis peroxisome organization regulation of peroxisome size signal transduction |
CD4-positive, alpha-beta T cell activation CD4-positive, alpha-beta T cell differentiation defense response to virus innate immune response negative regulation of protein secretion negative regulation of viral genome replication ossification positive regulation of immune response positive regulation of T-helper 2 cell cytokine production positive regulation of toll-like receptor 7 signaling pathway positive regulation of toll-like receptor 9 signaling pathway regulation of ossification response to virus |
adaptive immune response calcium-mediated signaling gene expression homeostasis of number of cells immune response inflammatory response integrin-mediated signaling pathway intracellular signal transduction lymphocyte homeostasis mast cell degranulation Ras protein signal transduction regulation of T cell activation T cell receptor signaling pathway |
bone development clustering of voltage-gated sodium channels ERBB2-ERBB3 signaling pathway myelination in peripheral nervous system negative regulation of cell-matrix adhesion negative regulation of Rho protein signal transduction negative regulation of stress fiber assembly neuron projection development non-canonical Wnt signaling pathway osteoblast differentiation positive regulation of cell migration positive regulation of focal adhesion assembly positive regulation of JNK cascade positive regulation of mitochondrial depolarization positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of stress fiber assembly positive regulation of substrate adhesion-dependent cell spreading regulation of MAPK cascade signal transduction skeletal muscle hypertrophy |
cGMP catabolic process cGMP metabolic process negative regulation of neural precursor cell proliferation positive regulation of cardiac muscle hypertrophy positive regulation of long-term synaptic potentiation signal transduction |
retinoid metabolic process |
protein complex oligomerization suppression by virus of host autophagy virus-mediated pore formation in host cell membrane |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral protein processing virion attachment to host cell virus-mediated perturbation of host defense response |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy |
DNA-templated transcription proteolysis viral process |
viral budding from plasma membrane viral budding via host ESCRT complex |
cellular response to glucocorticoid stimulus cellular response to steroid hormone stimulus chromatin organization positive regulation of transcription by RNA polymerase II |
dorsal/ventral neural tube patterning neural crest cell differentiation neural crest cell fate commitment neural crest formation neural plate development neurogenesis positive regulation of DNA-templated transcription positive regulation of protein import into nucleus positive regulation of transcription by RNA polymerase II positive regulation of Wnt signaling pathway Wnt signaling pathway |
calcium ion transmembrane transport calcium ion transmembrane transport via high voltage-gated calcium channel calcium ion transport into cytosol cardiac conduction regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
determination of dorsal identity nervous system development neural crest cell development neural crest formation pronephric duct development sequestering of BMP in extracellular matrix somite rostral/caudal axis specification |
chromatin organization chromosome condensation nucleate erythrocyte maturation |
angiogenesis blood vessel development endothelial cell-cell adhesion heart development phosphorylation positive regulation of angiogenesis transmembrane receptor protein tyrosine kinase signaling pathway vasculature development |
neuron cellular homeostasis removal of superoxide radicals response to metal ion response to methylmercury response to xenobiotic stimulus |
angioblast cell migration involved in selective angioblast sprouting anterior/posterior pattern specification axon guidance axon target recognition blood vessel development blood vessel morphogenesis cell adhesion cell migration involved in sprouting angiogenesis ephrin receptor signaling pathway optic vesicle morphogenesis regulation of chemotaxis rhombomere boundary formation somitogenesis synaptic target recognition |
angioblast cell migration involved in selective angioblast sprouting angiogenesis blood vessel development convergent extension ephrin receptor signaling pathway lymph vessel development phosphorylation venous blood vessel morphogenesis |
angiogenesis ephrin receptor signaling pathway Kupffer's vesicle development phosphorylation somitogenesis |
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