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bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion protein-containing complex assembly |
chromatin organization negative regulation of transcription by RNA polymerase II |
artery development cell redox homeostasis circulatory system development dehydroascorbic acid transport embryonic skeletal joint development galactose transmembrane transport glucose import across plasma membrane glucose transmembrane transport hexose transmembrane transport negative regulation of connective tissue growth factor production negative regulation of gene expression negative regulation of integrin-mediated signaling pathway negative regulation of proteoglycan biosynthetic process negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of gene expression positive regulation of proteoglycan biosynthetic process positive regulation of transforming growth factor beta receptor signaling pathway regulation of extracellular matrix organization skin development transport across blood-brain barrier |
ATP metabolic process NAD metabolic process NADP biosynthetic process phosphorylation positive regulation of insulin secretion involved in cellular response to glucose stimulus |
cell surface receptor signaling pathway double-strand break repair neuron development |
acetyl-CoA biosynthetic process from pyruvate mitochondrial pyruvate transmembrane transport positive regulation of insulin secretion involved in cellular response to glucose stimulus |
peptidyl-lysine monomethylation regulation of ribosome biogenesis regulation of rRNA processing regulation of translation regulation of translational elongation |
glutathione metabolic process hydrogen sulfide metabolic process |
fatty acid metabolic process long-chain fatty acid import into cell long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process long-chain fatty-acyl-CoA metabolic process neuron differentiation positive regulation of Golgi to plasma membrane protein transport positive regulation of phosphatidylcholine biosynthetic process positive regulation of secretion very-low-density lipoprotein particle assembly |
negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II |
chromatin remodeling mitotic cell cycle positive regulation of DNA-templated transcription positive regulation of double-strand break repair via homologous recombination regulation of apoptotic process regulation of cell cycle regulation of DNA-templated transcription regulation of double-strand break repair regulation of transcription by RNA polymerase II |
nuclear-transcribed mRNA poly(A) tail shortening protein autoubiquitination protein ubiquitination regulation of megakaryocyte differentiation ubiquitin-dependent protein catabolic process |
hippocampal neuron apoptotic process mitotic cytokinesis negative regulation of hippocampal neuron apoptotic process negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of Ras protein signal transduction positive regulation of cell population proliferation protein deubiquitination proteolysis receptor signaling pathway via JAK-STAT |
anterior/posterior axon guidance apoptotic process Cdc42 protein signal transduction cell-cell adhesion chemorepulsion of axon glial cell proliferation inner ear morphogenesis mammary gland duct morphogenesis motor neuron migration negative regulation of axon extension nuclear migration positive regulation of axon extension positive regulation of cell motility positive regulation of glial cell proliferation Ras protein signal transduction regulation of glial cell migration regulation of synapse assembly regulation of transcription by RNA polymerase II substrate-dependent cell migration, cell extension |
cell differentiation hematopoietic progenitor cell differentiation negative regulation of activin receptor signaling pathway negative regulation of BMP signaling pathway negative regulation of osteoclast differentiation negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway ossification positive regulation of cell-cell adhesion positive regulation of transcription by RNA polymerase II regulation of BMP signaling pathway regulation of transcription by RNA polymerase II |
mRNA processing |
aortic valve morphogenesis calcineurin-NFAT signaling cascade cellular response to transforming growth factor beta stimulus cellular response to tumor necrosis factor intracellular signal transduction mononuclear cell differentiation negative regulation of vascular associated smooth muscle cell differentiation negative regulation of Wnt signaling pathway positive regulation of DNA biosynthetic process positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II pulmonary valve morphogenesis regulation of transcription by RNA polymerase II response to muscle activity skeletal muscle adaptation wound healing |
regulation of macroautophagy synaptic vesicle lumen acidification |
methylation nucleotide metabolic process |
neuropeptide signaling pathway protein processing respiratory system process |
CDP-diacylglycerol biosynthetic process lipid droplet formation phosphatidylglycerol biosynthetic process |
anatomical structure development anatomical structure morphogenesis cell differentiation chromatin organization DNA repair inner ear development negative regulation of extrinsic apoptotic signaling pathway in absence of ligand positive regulation of DNA repair visual perception |
hematopoietic progenitor cell differentiation intermediate filament organization keratinization |
cell projection organization microtubule anchoring negative regulation of protein kinase activity positive regulation of cell growth positive regulation of cell migration positive regulation of cell population proliferation |
positive regulation of protein secretion regulation of DNA-templated transcription |
rRNA processing tRNA 5'-leader removal |
antimicrobial humoral immune response mediated by antimicrobial peptide cell-cell signaling chemotaxis signal transduction |
bone resorption positive regulation of regulated secretory pathway protein localization to plasma membrane protein secretion regulation of exocytosis vesicle docking involved in exocytosis |
cell dedifferentiation cell population proliferation inner ear development intracellular steroid hormone receptor signaling pathway negative regulation of stem cell differentiation photoreceptor cell maintenance positive regulation of DNA-templated transcription positive regulation of stem cell population maintenance positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of stem cell division regulation of transcription by RNA polymerase II stem cell division stem cell population maintenance |
autophagosome maturation autophagosome membrane docking cilium assembly exocytosis membrane fusion protein transport synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle priming vesicle targeting |
adaptive immune response cell recognition detection of stimulus detection of tumor cell establishment of T cell polarity heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules lymphocyte migration into lymphoid organs negative regulation of activated T cell proliferation positive regulation of cytokine production positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target positive regulation of type II interferon production regulation of CD8-positive, alpha-beta T cell activation regulation of T cell activation regulation of T cell differentiation |
cell differentiation cellular response to calcium ion positive regulation of dendrite extension postsynaptic actin cytoskeleton organization |
cell volume homeostasis cellular hyperosmotic response cellular hypotonic response cellular response to chemokine chemokine (C-C motif) ligand 21 signaling pathway chemokine (C-X-C motif) ligand 12 signaling pathway intracellular signal transduction negative regulation of potassium ion transmembrane transport osmosensory signaling pathway peptidyl-threonine phosphorylation positive regulation of T cell chemotaxis protein autophosphorylation protein phosphorylation renal sodium ion absorption response to oxidative stress response to xenobiotic stimulus signal transduction |
farnesyl diphosphate biosynthetic process geranyl diphosphate biosynthetic process geranylgeranyl diphosphate biosynthetic process isoprenoid biosynthetic process isoprenoid metabolic process |
animal organ morphogenesis cell differentiation fibroblast growth factor receptor signaling pathway negative regulation of bile acid biosynthetic process negative regulation of gene expression nervous system development positive regulation of cell population proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of gene expression positive regulation of glucose import positive regulation of JNK cascade positive regulation of protein phosphorylation regulation of cell migration |
axon guidance cell-cell signaling negative chemotaxis negative regulation of axon extension involved in axon guidance nervous system development neural crest cell migration positive regulation of cell migration retinal ganglion cell axon guidance semaphorin-plexin signaling pathway |
anatomical structure morphogenesis erythrocyte maturation mRNA processing negative regulation of RNA splicing regulation of cell differentiation regulation of RNA splicing RNA splicing |
cholesterol transport vesicle tethering to endoplasmic reticulum |
mRNA splicing, via spliceosome |
clathrin-dependent endocytosis endocytosis Golgi to endosome transport intracellular protein transport negative regulation of hyaluronan biosynthetic process positive regulation of neuron projection development positive regulation of receptor-mediated endocytosis postsynaptic neurotransmitter receptor internalization vesicle-mediated transport |
anterograde dendritic transport of messenger ribonucleoprotein complex cellular response to oxidative stress germ cell development intracellular mRNA localization lncRNA-mediated post-transcriptional gene silencing modification of postsynaptic structure positive regulation by virus of viral protein levels in host cell positive regulation of long-term synaptic potentiation positive regulation of viral genome replication protein localization to synapse |
defense response to virus innate immune response protein folding |
heparan sulfate proteoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process heparin biosynthetic process |
plasma membrane tubulation |
anterior/posterior axis specification anterior/posterior pattern specification bone mineralization cell migration involved in gastrulation cellular response to cadmium ion determination of dorsal identity determination of heart left/right asymmetry gastrulation growth plate cartilage chondrocyte proliferation negative regulation of activin receptor signaling pathway negative regulation of BMP signaling pathway negative regulation of cell population proliferation negative regulation of mesoderm development nervous system development sequestering of BMP in extracellular matrix signal transduction involved in regulation of gene expression ureteric bud development |
negative regulation of protein binding negative regulation of protein ubiquitination negative regulation of ubiquitin protein ligase activity positive regulation of proteasomal protein catabolic process positive regulation of protein processing protein folding protein metabolic process protein stabilization |
aggresome assembly autophagosome assembly cellular response to heat cellular response to mechanical stimulus cellular response to unfolded protein chaperone-mediated autophagy extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway via death domain receptors muscle cell cellular homeostasis negative regulation of apoptotic process negative regulation of striated muscle cell apoptotic process positive regulation of aggrephagy positive regulation of protein export from nucleus positive regulation of protein import into nucleus protein folding protein stabilization protein transport along microtubule striated muscle cell apoptotic process |
acetyl-CoA biosynthetic process acyl-CoA metabolic process fatty acid biosynthetic process fatty acid oxidation malonyl-CoA catabolic process positive regulation of fatty acid oxidation regulation of fatty acid beta-oxidation regulation of glucose metabolic process response to ischemia response to nutrient |
activation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic process cellular response to aldosterone cellular response to estradiol stimulus cellular response to hydrogen peroxide cellular response to hypoxia cellular response to nitric oxide chromosome condensation intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress mitochondrial respiratory chain complex assembly mitochondrial respiratory chain complex I assembly neuron apoptotic process neuron differentiation positive regulation of apoptotic process positive regulation of necroptotic process positive regulation of neuron apoptotic process protein import into mitochondrial intermembrane space regulation of apoptotic DNA fragmentation response to ischemia response to L-glutamate response to toxic substance |
bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell junction maintenance cell-cell junction organization cellular response to butyrate cellular response to lead ion cellular response to transforming growth factor beta stimulus cellular response to tumor necrosis factor cellular response to type II interferon establishment of blood-nerve barrier establishment of endothelial intestinal barrier establishment of skin barrier liver regeneration maintenance of blood-brain barrier positive regulation of bicellular tight junction assembly positive regulation of cell migration positive regulation of epithelial cell proliferation involved in wound healing positive regulation of wound healing protein complex oligomerization response to dexamethasone response to ethanol response to interleukin-18 response to lipopolysaccharide response to toxic substance xenobiotic transport across blood-nerve barrier |
chloride transport signal transduction |
microtubule cytoskeleton organization negative regulation of microtubule polymerization regulation of microtubule nucleation sensory perception of sound visual perception |
action potential adenylate cyclase-modulating G protein-coupled receptor signaling pathway phospholipase C-activating dopamine receptor signaling pathway signal transduction |
signal transduction visual perception |
inner ear development intracellular triglyceride homeostasis negative regulation of mitochondrial calcium ion concentration negative regulation of mitochondrial membrane potential negative regulation of neuron apoptotic process positive regulation of cell population proliferation regulation of glucose import response to cold |
nucleoside phosphate metabolic process protein N-linked glycosylation via asparagine ribose phosphate metabolic process |
negative regulation of Notch signaling pathway protein localization to plasma membrane protein maturation regulation of membrane protein ectodomain proteolysis |
3'-phosphoadenosine 5'-phosphosulfate metabolic process nervous system development nucleobase-containing compound metabolic process phosphatidylinositol phosphate biosynthetic process |
alpha-linolenic acid metabolic process linoleic acid metabolic process lipid metabolic process unsaturated fatty acid biosynthetic process |
arginine metabolic process citrulline metabolic process negative regulation of apoptotic process positive regulation of nitric oxide biosynthetic process |
blood coagulation erythrocyte differentiation integrin-mediated signaling pathway megakaryocyte development megakaryocyte differentiation negative regulation of signal transduction platelet formation |
acetylcholine receptor signaling pathway |
monoacylglycerol catabolic process phosphatidylserine catabolic process prostaglandin catabolic process |
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway |
modification of synaptic structure modulation of chemical synaptic transmission signaling |
mRNA processing mRNA pseudouridine synthesis positive regulation of mitochondrial translation tRNA processing |
fibroblast proliferation mRNA processing positive regulation of transcription by RNA polymerase II regulation of G1/S transition of mitotic cell cycle RNA splicing |
lactate transport monocarboxylic acid transport |
cerebellar Purkinje cell differentiation immune response in nasopharyngeal-associated lymphoid tissue microtubule cytoskeleton organization mucociliary clearance protein polyglutamylation regulation of blastocyst development sperm axoneme assembly |
defense response to bacterium negative regulation of calcium ion import negative regulation of flagellated sperm motility negative regulation of peptidase activity |
embryonic organ development gastrulation in utero embryonic development mitotic G2 DNA damage checkpoint signaling mRNA splicing, via spliceosome positive regulation of cell population proliferation |
cell fate specification cochlea morphogenesis morphogenesis of embryonic epithelium negative regulation of canonical Wnt signaling pathway negative regulation of transcription by RNA polymerase II neural plate anterior/posterior regionalization positive regulation of DNA-templated transcription regulation of SA node cell action potential regulation of transcription by RNA polymerase II sinoatrial node cell development sinoatrial node cell fate commitment sinoatrial node development smooth muscle cell differentiation somitogenesis ureter development |
adaptive immune response astrocyte differentiation brain development cardioblast differentiation CD8-positive, alpha-beta T cell differentiation involved in immune response cell differentiation involved in embryonic placenta development cerebral cortex neuron differentiation cerebral cortex regionalization chromatin remodeling DNA demethylation DNA methylation endoderm formation endodermal cell fate specification gene expression mesendoderm development mesoderm formation mesodermal to mesenchymal transition involved in gastrulation negative regulation of DNA-binding transcription factor activity negative regulation of transcription by RNA polymerase II neuron migration olfactory bulb development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II skeletal muscle cell differentiation stem cell population maintenance trophectodermal cell differentiation |
cellular defense response signal transduction |
anatomical structure morphogenesis cell fate specification heart looping mesoderm development mesodermal cell fate specification negative regulation of DNA-binding transcription factor activity negative regulation of neuron maturation negative regulation of neuron projection development negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II signal transduction involved in regulation of gene expression somite rostral/caudal axis specification vasculogenesis |
animal organ morphogenesis cell fate commitment cilium assembly endocrine pancreas development epithelial cell development liver development mesenchymal stem cell migration negative regulation of transforming growth factor beta receptor signaling pathway peripheral nervous system neuron development positive regulation of mesenchymal stem cell migration positive regulation of transcription by RNA polymerase II regulation of cell-matrix adhesion regulation of transcription by RNA polymerase II transforming growth factor beta receptor signaling pathway |
cytoskeleton organization folic acid-containing compound metabolic process histidine catabolic process to glutamate and formamide histidine catabolic process to glutamate and formate |
aorta development aorta smooth muscle tissue morphogenesis elastic fiber assembly negative regulation of vascular associated smooth muscle cell proliferation positive regulation of aortic smooth muscle cell differentiation positive regulation of collagen fibril organization positive regulation of smooth muscle cell-matrix adhesion regulation of collagen fibril organization vascular associated smooth muscle cell development |
axon guidance nervous system development neuron projection development neurotransmitter receptor localization to postsynaptic specialization membrane positive regulation of cell growth positive regulation of synaptic transmission |
adaptive immune response angiogenesis defense response to Gram-negative bacterium innate immune response mucosal immune response negative regulation of adaptive immune memory response negative regulation of angiogenesis negative regulation of CD4-positive, alpha-beta T cell costimulation negative regulation of T cell receptor signaling pathway phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of endothelial cell apoptotic process positive regulation of natural killer cell cytokine production positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated immune response to tumor cell positive regulation of type II interferon production T cell costimulation |
female gamete generation |
activation of phospholipase C activity adenylate cyclase-activating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway immune response positive regulation of cytosolic calcium ion concentration regulation of metabolic process |
blood vessel maturation canonical Wnt signaling pathway embryo implantation embryonic forelimb morphogenesis extracellular matrix organization negative regulation of cell migration negative regulation of metalloendopeptidase activity positive regulation of canonical Wnt signaling pathway regulation of angiogenesis regulation of establishment of blood-brain barrier sprouting angiogenesis |
chromatin remodeling DNA methylation-dependent heterochromatin formation embryonic organ development heart development in utero embryonic development negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription regulation of cell fate specification regulation of DNA methylation regulation of stem cell differentiation response to estradiol response to nutrient levels tissue development |
chromosome segregation DNA topological change |
adenosine 5'-(hexahydrogen pentaphosphate) catabolic process cell-cell signaling diadenosine hexaphosphate catabolic process diadenosine pentaphosphate catabolic process diadenosine polyphosphate catabolic process diphosphoinositol polyphosphate catabolic process diphosphoinositol polyphosphate metabolic process RNA decapping |
actin filament bundle assembly actin filament polymerization cell cycle cellular response to glucocorticoid stimulus cellular response to nutrient levels cognition negative regulation of focal adhesion assembly negative regulation of G1/S transition of mitotic cell cycle negative regulation of long-term synaptic potentiation positive regulation of cell migration positive regulation of protein ubiquitination regulation of actin cytoskeleton organization regulation of cell growth regulation of microtubule cytoskeleton organization regulation of protein stability |
B cell chemotaxis cholesterol metabolic process lipid metabolic process negative regulation of cholesterol metabolic process negative regulation of fusion of virus membrane with host plasma membrane response to type I interferon sterol biosynthetic process |
digestive tract morphogenesis inflammatory response lung goblet cell differentiation mucus secretion positive regulation of cell-substrate adhesion positive regulation of developmental growth positive regulation of epidermal growth factor receptor signaling pathway positive regulation of gene expression positive regulation of IRE1-mediated unfolded protein response positive regulation of PERK-mediated unfolded protein response positive regulation of protein localization to plasma membrane |
axoneme assembly brain development cilium movement involved in cell motility determination of left/right symmetry epithelial cilium movement involved in extracellular fluid movement establishment of localization in cell flagellated sperm motility negative regulation of cell population proliferation positive regulation of protein localization to cilium positive regulation of smoothened signaling pathway protein localization regulation of microtubule binding |
cell division chromosome organization DNA repair homologous chromosome segregation spermatogenesis |
cellular response to hydrogen peroxide cellular response to tumor necrosis factor response to lipopolysaccharide T-helper 1 type immune response |
angiogenesis blastocyst development cardiac left ventricle formation cardiac right ventricle formation cardiac septum morphogenesis cartilage morphogenesis embryonic heart tube development embryonic heart tube formation heart development heart looping mesenchyme development mesoderm formation negative regulation of DNA-binding transcription factor activity negative regulation of DNA-templated transcription negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding negative regulation of transcription by RNA polymerase II odontogenesis of dentin-containing tooth positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II trophectodermal cell differentiation trophoblast giant cell differentiation ventricular cardiac muscle tissue morphogenesis |
cell differentiation regulation of T cell differentiation in thymus |
negative regulation by host of viral genome replication positive regulation of transcription by RNA polymerase II protein autosumoylation protein sumoylation regulation of DNA-templated transcription regulation of transcription by RNA polymerase II |
Mo-molybdopterin cofactor biosynthetic process molybdopterin cofactor biosynthetic process |
monoatomic ion transport protein import into mitochondrial matrix protein insertion into mitochondrial outer membrane protein targeting to mitochondrion |
membrane protein proteolysis proteolysis surfactant homeostasis |
peroxisome fission peroxisome organization regulation of peroxisome size signal transduction |
apoptotic process cell cycle cell migration cellular response to organic cyclic compound cytoskeleton organization dendritic spine development intracellular signal transduction negative regulation of endothelial cell apoptotic process phosphorylation positive regulation of angiogenesis regulation of cell growth regulation of MAPK cascade signal transduction |
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