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cell differentiation mRNA transcription by RNA polymerase II negative regulation of RNA polymerase II transcription preinitiation complex assembly negative regulation of transcription by RNA polymerase II positive regulation of thyroid hormone mediated signaling pathway positive regulation of transcription by RNA polymerase II retinoic acid receptor signaling pathway thyroid hormone mediated signaling pathway |
MAPK cascade negative regulation of apoptotic process phosphorylation positive regulation of peptidyl-serine phosphorylation regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of TOR signaling |
adaptive thermogenesis astrocyte differentiation cell adhesion cellular response to hypoxia learning or memory long-term synaptic potentiation memory negative regulation of skeletal muscle cell differentiation neuron projection extension positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of cell population proliferation positive regulation of myelination positive regulation of neuron differentiation positive regulation of synaptic transmission regulation of cell shape regulation of neuronal synaptic plasticity response to glucocorticoid response to methylmercury sympathetic neuron projection extension |
positive regulation of cell population proliferation proteolysis regulation of macroautophagy |
adaptive thermogenesis brown fat cell differentiation cellular response to cold cellular response to dehydroepiandrosterone cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species diet induced thermogenesis generation of precursor metabolites and energy mitochondrial transmembrane transport mitochondrial transport positive regulation of cold-induced thermogenesis positive regulation of metabolic process proton transmembrane transport regulation of reactive oxygen species biosynthetic process regulation of transcription by RNA polymerase II response to cold response to nutrient levels response to temperature stimulus |
lipid catabolic process malate metabolic process |
lipid catabolic process phosphatidylcholine catabolic process triglyceride catabolic process |
aerobic respiration gluconeogenesis malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle |
cellular response to extracellular stimulus glucose catabolic process to lactate via pyruvate lactate metabolic process liver development NAD metabolic process positive regulation of apoptotic process pyruvate catabolic process pyruvate metabolic process response to cAMP response to estrogen response to glucose response to hydrogen peroxide response to hypoxia response to nutrient response to organic cyclic compound response to xenobiotic stimulus skeletal muscle tissue development |
mitochondrial electron transport, cytochrome c to oxygen mitochondrial electron transport, ubiquinol to cytochrome c oxidative phosphorylation regulation of compound eye retinal cell programmed cell death sperm individualization |
nodulation purine nucleobase catabolic process urate catabolic process |
microtubule cytoskeleton organization mitotic cell cycle nuclear division nuclear migration by microtubule mediated pushing forces |
cytoplasmic microtubule organization microtubule cytoskeleton organization mitochondrion distribution mitotic cell cycle mitotic spindle organization nuclear division nuclear migration by microtubule mediated pushing forces |
actin filament capping actin filament organization cardiac muscle contraction cellular response to reactive oxygen species in utero embryonic development muscle contraction muscle filament sliding negative regulation of cell migration negative regulation of vascular associated smooth muscle cell migration negative regulation of vascular associated smooth muscle cell proliferation positive regulation of ATP-dependent activity positive regulation of cell adhesion positive regulation of heart rate by epinephrine positive regulation of stress fiber assembly regulation of cell shape ruffle organization sarcomere organization ventricular cardiac muscle tissue morphogenesis wound healing |
aspartate biosynthetic process L-phenylalanine biosynthetic process from chorismate via phenylpyruvate leucine biosynthetic process tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway negative regulation of cyclic-nucleotide phosphodiesterase activity phototransduction response to light stimulus visual perception |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway background adaptation cell morphogenesis cone retinal bipolar cell differentiation detection of chemical stimulus involved in sensory perception of bitter taste detection of light stimulus involved in visual perception dopamine metabolic process gene expression homeostasis of number of retina cells L-glutamate import neural tissue regeneration phototransduction protein localization reactive gliosis response to organic cyclic compound response to UV retinal cone cell development retinal rod cell differentiation tissue remodeling visual behavior |
aerobic respiration heme biosynthetic process heme transport mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport mitochondrial transport |
carbon fixation leaf development photosynthesis response to ammonium ion response to cytokinin response to nitrate tricarboxylic acid cycle |
photorespiration reductive pentose-phosphate cycle |
cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth |
cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth |
cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth |
carbohydrate catabolic process carbohydrate metabolic process polysaccharide digestion |
mesenchyme migration positive regulation of gene expression |
monoatomic cation transport muscle cell cellular homeostasis musculoskeletal movement neuromuscular junction development neuromuscular process neuromuscular synaptic transmission neuron cellular homeostasis neuronal action potential regulation of membrane potential response to nicotine skeletal muscle contraction skeletal muscle tissue growth synaptic transmission, cholinergic |
acetylcholine receptor signaling pathway behavioral response to nicotine excitatory postsynaptic potential heart development locomotory behavior nervous system development presynaptic modulation of chemical synaptic transmission regulation of acetylcholine secretion, neurotransmission regulation of dendrite morphogenesis regulation of membrane potential regulation of muscle contraction regulation of smooth muscle contraction response to acetylcholine response to carbon monoxide response to inorganic substance response to nicotine response to xenobiotic stimulus signal transduction synaptic transmission involved in micturition synaptic transmission, cholinergic |
behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization signal transduction synaptic transmission, cholinergic |
musculoskeletal movement skeletal muscle tissue growth |
monoatomic cation transport regulation of membrane potential skeletal muscle contraction |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission cognition entrainment of circadian clock G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger phototransduction, visible light regulation of locomotion saliva secretion |
canonical glycolysis cellular response to hypoxia cellular response to interleukin-7 ERK1 and ERK2 cascade gluconeogenesis glycolytic process in utero embryonic development negative regulation of cell growth negative regulation of DNA-templated transcription negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway negative regulation of transcription by RNA polymerase II positive regulation of ATP biosynthetic process positive regulation of muscle contraction positive regulation of plasminogen activation response to virus |
female pregnancy hematopoietic stem cell proliferation mammary gland development positive regulation of cell population proliferation positive regulation of hematopoietic stem cell proliferation positive regulation of lactation positive regulation of receptor signaling pathway via JAK-STAT response to nutrient levels |
blood vessel endothelial cell migration female pregnancy mammary gland development negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration placenta blood vessel development placenta development positive regulation of cell population proliferation positive regulation of lactation positive regulation of receptor signaling pathway via JAK-STAT response to nutrient levels |
angiogenesis glutamine biosynthetic process protein palmitoylation regulation of endothelial cell migration regulation of sprouting angiogenesis |
photosynthesis, light harvesting |
cellular response to hypoxia cellular response to interleukin-7 endoplasmic reticulum to Golgi vesicle-mediated transport insulin processing positive regulation of cell adhesion positive regulation of substrate adhesion-dependent cell spreading positive regulation of viral entry into host cell protein folding protein folding in endoplasmic reticulum regulation of oxidative stress-induced intrinsic apoptotic signaling pathway response to endoplasmic reticulum stress |
chromatin organization chromosome segregation DNA replication DNA strand elongation involved in DNA replication DNA topological change mitotic chromosome condensation nuclear migration rDNA heterochromatin formation regulation of mitotic recombination regulation of transcription by RNA polymerase II rRNA transcription transcription elongation by RNA polymerase II |
anterograde axonal protein transport cellular response to vascular endothelial growth factor stimulus chaperone-mediated protein folding intracellular signal transduction negative regulation of apoptotic process negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway negative regulation of protein kinase activity platelet aggregation positive regulation of angiogenesis positive regulation of blood vessel endothelial cell migration positive regulation of endothelial cell chemotaxis positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway positive regulation of interleukin-1 beta production positive regulation of tumor necrosis factor production protein refolding regulation of autophagy regulation of canonical NF-kappaB signal transduction regulation of protein phosphorylation regulation of translational initiation response to heat response to unfolded protein response to virus |
antimicrobial humoral immune response mediated by antimicrobial peptide cAMP-mediated signaling canonical glycolysis cellular response to type II interferon female pregnancy gluconeogenesis glycolytic process microtubule cytoskeleton organization negative regulation of translation negative regulation of vascular associated smooth muscle cell apoptotic process neuron apoptotic process nitric oxide mediated signal transduction peptidyl-cysteine S-trans-nitrosylation positive regulation of canonical NF-kappaB signal transduction positive regulation of cytokine production positive regulation of type I interferon production protein stabilization |
oxidative demethylation response to cadmium ion response to dexamethasone response to glucocorticoid response to metal ion response to nutrient response to xenobiotic stimulus steroid metabolic process xenobiotic metabolic process |
aspartyl-tRNA aminoacylation |
glutamyl-tRNA aminoacylation |
carbohydrate phosphorylation fructose import across plasma membrane fructose metabolic process glucose 6-phosphate metabolic process glucose import glucose metabolic process glycolytic process intracellular glucose homeostasis mannose metabolic process |
carbohydrate phosphorylation fructose import across plasma membrane fructose metabolic process glucose 6-phosphate metabolic process glucose import glucose metabolic process glycolytic process intracellular glucose homeostasis mannose metabolic process negative regulation of apoptotic signaling pathway regulation of cell size regulation of transcription by glucose |
centrosome cycle cold acclimation negative regulation of cell population proliferation pole plasm mRNA localization positive regulation of insulin receptor signaling pathway positive regulation of neuroblast proliferation proteasome assembly regulation of circadian sleep/wake cycle, sleep response to heat RISC complex assembly |
amino acid transmembrane transport basic amino acid transport L-arginine transmembrane transport transmembrane transport |
cartilage development circadian rhythm developmental growth DNA biosynthetic process dTMP biosynthetic process dTTP biosynthetic process intestinal epithelial cell maturation liver regeneration methylation negative regulation of translation response to cytokine response to ethanol response to folic acid response to glucocorticoid response to organophosphorus response to progesterone response to toxic substance response to vitamin A response to xenobiotic stimulus tetrahydrofolate interconversion uracil metabolic process |
base-excision repair cell division DNA biosynthetic process DNA ligation DNA recombination lagging strand elongation maintenance of DNA trinucleotide repeats mitotic cell cycle nucleotide-excision repair Okazaki fragment processing involved in mitotic DNA replication |
cellular response to heat connective tissue replacement involved in inflammatory response wound healing cytokine-mediated signaling pathway ectopic germ cell programmed cell death extrinsic apoptotic signaling pathway in absence of ligand fever generation immune response intracellular sodium ion homeostasis negative regulation of cell population proliferation positive regulation of angiogenesis positive regulation of cell division positive regulation of interleukin-2 production positive regulation of mitotic nuclear division positive regulation of protein secretion positive regulation of transcription by RNA polymerase II positive regulation of vascular endothelial growth factor production response to copper ion |
carbohydrate metabolic process |
proteolysis |
cardiac left ventricle morphogenesis insulin processing peptide hormone secretion peptide metabolic process protein localization to membrane protein localization to secretory granule protein processing Wnt signaling pathway |
cellular response to cadmium ion cellular response to ethanol cellular response to L-glutamine defense response electron transport chain hydrogen peroxide biosynthetic process hypoxia-inducible factor-1alpha signaling pathway inflammatory response innate immune response monoatomic ion transmembrane transport positive regulation of angiogenesis positive regulation of tumor necrosis factor production respiratory burst response to aldosterone response to angiotensin response to nutrient response to xenobiotic stimulus superoxide anion generation superoxide metabolic process |
methane catabolic process methanol metabolic process |
protein N-linked glycosylation protein N-linked glycosylation via asparagine |
viral budding from plasma membrane viral entry into host cell virion attachment to host cell |
viral entry into host cell virion attachment to host cell |
DNA-templated transcription negative stranded viral RNA replication |
transport of virus in host, cell to cell |
adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling positive regulation of GTPase activity sensory perception of chemical stimulus |
lipid metabolic process xenobiotic catabolic process xenobiotic metabolic process |
cellular detoxification of nitrogen compound cellular response to xenobiotic stimulus glutathione derivative biosynthetic process glutathione metabolic process hepoxilin biosynthetic process nitrobenzene metabolic process prostaglandin metabolic process response to amino acid response to axon injury response to ethanol response to lead ion response to metal ion response to xenobiotic stimulus sensory perception of smell xenobiotic catabolic process |
chromatin organization negative regulation of cell population proliferation protein localization to CENP-A containing chromatin |
chromatin remodeling double-strand break repair homologous chromosome segregation mitotic chromosome condensation mitotic DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling |
chromatin remodeling double-strand break repair homologous chromosome segregation mitotic chromosome condensation mitotic DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling |
chromatin organization DNA repair negative regulation of transcription by RNA polymerase II |
chromatin organization DNA repair |
chromatin remodeling double-strand break repair via homologous recombination |
cardiac muscle tissue development detection of light stimulus involved in visual perception embryonic organ morphogenesis embryonic retina morphogenesis in camera-type eye embryonic skeletal system development eye development female genitalia morphogenesis gluconeogenesis glucose homeostasis heart development heart trabecula formation lung development maintenance of gastrointestinal epithelium male gonad development negative regulation of cardiac muscle cell proliferation positive regulation of immunoglobulin production positive regulation of insulin secretion response to ethanol response to insulin response to muscle activity response to retinoic acid response to xenobiotic stimulus retina development in camera-type eye retinal metabolic process retinol metabolic process retinol transport spermatogenesis urinary bladder development uterus development vagina development vitamin A import into cell |
apoptotic process biomineral tissue development granzyme-mediated programmed cell death signaling pathway maintenance of granzyme B location in T cell secretory granule maintenance of protease location in mast cell secretory granule mast cell secretory granule organization modulation of chemical synaptic transmission negative regulation of bone mineralization negative regulation of cytokine production protein processing regulation of postsynapse organization secretory granule organization T cell secretory granule organization |
bicarbonate transport blood coagulation chloride transmembrane transport chloride transport erythrocyte development negative regulation of glycolytic process through fructose-6-phosphate negative regulation of urine volume pH elevation plasma membrane phospholipid scrambling positive regulation of T cell proliferation protein localization to plasma membrane regulation of intracellular pH response to activity response to arsenic-containing substance response to carbon dioxide response to hydrogen peroxide transmembrane transport |
aerobic respiration cellular response to lipid cellular response to testosterone stimulus energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response to glucose stimulus negative regulation of lipid biosynthetic process negative regulation of lipid storage positive regulation of gene expression positive regulation of glucose metabolic process positive regulation of lipid metabolic process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response to glucose stimulus negative regulation of lipid biosynthetic process negative regulation of lipid storage positive regulation of gene expression positive regulation of glucose metabolic process positive regulation of lipid metabolic process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to stilbenoid |
absorption of UV light cellular response to light stimulus detection of UV G protein-coupled receptor signaling pathway phototransduction phototransduction, UV visual perception |
base-excision repair, gap-filling cellular response to hydrogen peroxide cellular response to UV cellular response to xenobiotic stimulus epithelial cell differentiation estrous cycle heart development leading strand elongation liver regeneration mismatch repair mitotic telomere maintenance via semi-conservative replication negative regulation of transcription by RNA polymerase II positive regulation of deoxyribonuclease activity positive regulation of DNA repair positive regulation of DNA replication replication fork processing response to cadmium ion response to dexamethasone response to estradiol response to L-glutamate response to lipid response to oxidative stress translesion synthesis |
proteolysis |
positive regulation of epidermal growth factor receptor signaling pathway positive regulation of G protein-coupled receptor signaling pathway positive regulation of MAPK cascade response to stimulus visual perception |
clathrin-dependent endocytosis intracellular protein transport |
D-ribose catabolic process |
D-ribose transmembrane transport |
photorespiration reductive pentose-phosphate cycle |
DNA damage response DNA recombination double-strand break repair via homologous recombination recombinational repair |
DNA catabolic process mismatch repair |
adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein regulation of cell cycle response to exogenous dsRNA response to virus T cell activation involved in immune response type I interferon-mediated signaling pathway |
adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein response to exogenous dsRNA T cell activation involved in immune response type I interferon-mediated signaling pathway |
adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein response to exogenous dsRNA response to virus T cell activation involved in immune response type I interferon-mediated signaling pathway |
de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process pyrimidine nucleotide biosynthetic process |
cardiac muscle cell action potential involved in contraction cell communication by electrical coupling involved in cardiac conduction cellular response to steroid hormone stimulus establishment or maintenance of transmembrane electrochemical gradient intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization membrane repolarization during cardiac muscle cell action potential negative regulation of glucocorticoid biosynthetic process negative regulation of heart contraction positive regulation of heart contraction positive regulation of striated muscle contraction potassium ion import across plasma membrane proton transmembrane transport regulation of blood pressure regulation of sodium ion transport regulation of the force of heart contraction relaxation of cardiac muscle response to glycoside response to xenobiotic stimulus sodium ion export across plasma membrane |
establishment or maintenance of transmembrane electrochemical gradient intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization potassium ion import across plasma membrane proton transmembrane transport regulation of sodium ion transport sodium ion export across plasma membrane transmembrane transport |
ATP metabolic process cardiac muscle contraction cell adhesion establishment or maintenance of transmembrane electrochemical gradient innate immune response intracellular calcium ion homeostasis intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization positive regulation of P-type sodium:potassium-exchanging transporter activity positive regulation of potassium ion import across plasma membrane positive regulation of sodium ion export across plasma membrane potassium ion import across plasma membrane protein localization to plasma membrane protein stabilization proton transmembrane transport regulation of calcium ion transmembrane transport regulation of cardiac muscle contraction by calcium ion signaling regulation of gene expression relaxation of cardiac muscle sodium ion export across plasma membrane transmembrane transport |
ATP metabolic process cardiac muscle contraction cell adhesion innate immune response intracellular calcium ion homeostasis intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization positive regulation of potassium ion import across plasma membrane positive regulation of sodium ion export across plasma membrane potassium ion import across plasma membrane protein localization to plasma membrane protein stabilization regulation of calcium ion transmembrane transport regulation of cardiac muscle contraction by calcium ion signaling regulation of gene expression relaxation of cardiac muscle sodium ion export across plasma membrane |
positive regulation of TORC1 signaling proteasome storage granule assembly proton export across plasma membrane proton transmembrane transport regulation of intracellular pH transmembrane transport |
adult chitin-containing cuticle pigmentation anesthesia-resistant memory catecholamine metabolic process dopamine biosynthetic process from tyrosine long-term memory regulation of adult chitin-containing cuticle pigmentation response to hydrogen peroxide response to wounding serotonin biosynthetic process serotonin biosynthetic process from tryptophan thermosensory behavior thermotaxis wing disc development |
folic acid biosynthetic process para-aminobenzoic acid biosynthetic process tetrahydrofolate biosynthetic process tryptophan biosynthetic process |
fumarate metabolic process malate metabolic process response to oxidative stress tricarboxylic acid cycle |
DNA dealkylation involved in DNA repair DNA demethylation DNA repair oxidative demethylation oxidative RNA demethylation oxidative single-stranded DNA demethylation oxidative single-stranded RNA demethylation response to methyl methanesulfonate RNA repair |
mRNA catabolic process response to heat RNA catabolic process RNA processing |
adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation defense response to bacterium defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium innate immune response killing of cells of another organism mast cell activation mast cell chemotaxis mast cell degranulation negative regulation of angiogenesis negative regulation of catecholamine secretion negative regulation of hormone secretion negative regulation of insulin secretion positive regulation of dense core granule biogenesis regulation of cell adhesion |
fructose 1,6-bisphosphate metabolic process fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate fructose metabolic process gluconeogenesis glycolytic process NADH oxidation negative regulation of pentose-phosphate shunt positive regulation of ATP-dependent activity vacuolar proton-transporting V-type ATPase complex assembly |
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