text
stringlengths
7
1.01k
cellular response to fatty acid cellular response to nutrient cholesterol homeostasis chylomicron remodeling fatty acid biosynthetic process low-density lipoprotein particle mediated signaling phospholipid metabolic process positive regulation of adipose tissue development positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of cholesterol storage positive regulation of fat cell differentiation positive regulation of inflammatory response positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of macrophage derived foam cell differentiation positive regulation of sequestering of triglyceride positive regulation of tumor necrosis factor production response to bacterium response to glucose triglyceride catabolic process triglyceride homeostasis triglyceride metabolic process very-low-density lipoprotein particle remodeling
chylomicron remodeling fatty acid metabolic process triglyceride catabolic process
phosphorylation photosynthesis pyruvate metabolic process
2'-deoxyribonucleotide biosynthetic process blastocyst development deoxyribonucleotide biosynthetic process deoxyribonucleotide metabolic process positive regulation of G1/S transition of mitotic cell cycle protein heterotetramerization ribonucleoside diphosphate metabolic process
aorta development brain development brain segmentation cellular response to organic substance facial nerve structural organization fat cell differentiation gene expression learning or memory motor neuron axon guidance myelination peripheral nervous system development positive regulation of DNA-templated transcription positive regulation of myelination positive regulation of Schwann cell differentiation positive regulation of transcription by RNA polymerase II protein export from nucleus protein sumoylation regulation of neuronal synaptic plasticity regulation of ossification regulation of transcription by RNA polymerase II response to insulin rhombomere 3 formation rhombomere 3 structural organization rhombomere 5 formation rhombomere 5 structural organization rhythmic behavior Schwann cell differentiation skeletal muscle cell differentiation
cellular hyperosmotic response cellular response to glucose starvation cellular response to mechanical stimulus central nervous system development cerebral cortex development dehydroascorbic acid transport female pregnancy glucose import glucose import across plasma membrane glucose transmembrane transport L-ascorbic acid metabolic process long-chain fatty acid import across plasma membrane photoreceptor cell maintenance protein-containing complex assembly response to hypoxia response to insulin response to Thyroglobulin triiodothyronine transport across blood-brain barrier
cellular hyperosmotic response cellular response to glucose starvation cellular response to mechanical stimulus central nervous system development cerebral cortex development dehydroascorbic acid transport female pregnancy glucose import glucose import across plasma membrane glucose transmembrane transport long-chain fatty acid import across plasma membrane photoreceptor cell maintenance protein-containing complex assembly response to hypoxia response to insulin response to Thyroglobulin triiodothyronine transport across blood-brain barrier xenobiotic transport
carbohydrate metabolic process dehydroascorbic acid transport fructose transmembrane transport galactose transmembrane transport glucose import glucose transmembrane transport positive regulation of insulin secretion involved in cellular response to glucose stimulus
carbohydrate metabolic process dehydroascorbic acid transport galactose transmembrane transport glucose import glucose import across plasma membrane glucose transmembrane transport L-ascorbic acid metabolic process transport across blood-brain barrier
alpha-glucoside transport fucose transmembrane transport galactose transmembrane transport glucose transmembrane transport intestinal D-glucose absorption myo-inositol transport pentose transmembrane transport renal glucose absorption
actin cytoskeleton organization actomyosin structure organization cell cycle cell division cortical actin cytoskeleton organization positive regulation of protein binding positive regulation of protein localization to cell cortex protein-containing complex assembly regulation of calcium ion transport regulation of intestinal absorption
de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process cellular response to xenobiotic stimulus female pregnancy lactation pyrimidine nucleobase biosynthetic process UDP biosynthetic process UMP biosynthetic process
acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle
2-oxoglutarate metabolic process histone succinylation L-lysine catabolic process to acetyl-CoA via saccharopine succinyl-CoA metabolic process tricarboxylic acid cycle
glucose metabolic process tricarboxylic acid cycle
carboxylic acid metabolic process
branched-chain amino acid catabolic process
disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity
negative regulation of fibrinolysis negative regulation of plasminogen activation negative regulation of proteolysis plasminogen activation platelet-derived growth factor receptor signaling pathway prevention of polyspermy proteolysis response to hypoxia smooth muscle cell migration synaptic transmission, glutamatergic trans-synaptic signaling by BDNF, modulating synaptic transmission
glycogen catabolic process
glycogen catabolic process glycogen metabolic process
acute-phase response antiviral innate immune response cell surface pattern recognition receptor signaling pathway complement activation, classical pathway complement activation, lectin pathway defense response to bacterium defense response to Gram-positive bacterium innate immune response killing by host of symbiont cells negative regulation of viral process opsonization positive regulation of opsonization positive regulation of phagocytosis proteolysis response to oxidative stress surfactant homeostasis
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission cognition G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger nervous system development neuromuscular synaptic transmission phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway positive regulation of intracellular protein transport positive regulation of monoatomic ion transport postsynaptic modulation of chemical synaptic transmission protein kinase C-activating G protein-coupled receptor signaling pathway regulation of glial cell proliferation regulation of locomotion regulation of postsynaptic membrane potential saliva secretion signal transduction
behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization regulation of membrane potential signal transduction synaptic transmission, cholinergic
cell redox homeostasis cellular detoxification of hydrogen peroxide cellular response to antibiotic cellular response to glucose stimulus cellular response to hyperoxia cellular response to xenobiotic stimulus negative regulation of protein export from nucleus negative regulation of transcription by RNA polymerase II positive regulation of DNA binding positive regulation of peptidyl-cysteine S-nitrosylation positive regulation of peptidyl-serine phosphorylation response to activity response to axon injury response to dexamethasone response to nitric oxide response to radiation response to selenium ion response to thyroxine response to xenobiotic stimulus
cell cycle cell division chemotaxis establishment of protein localization to mitochondrion exocytosis membrane raft localization neural tube closure positive regulation of epidermal growth factor receptor signaling pathway positive regulation of filopodium assembly positive regulation of mitochondrial fission Ras protein signal transduction receptor internalization regulation of actin cytoskeleton organization regulation of exocytosis regulation of postsynaptic neurotransmitter receptor internalization signal transduction
apoptotic process cell cycle cell division cellular response to exogenous dsRNA cellular response to starvation negative regulation of protein binding positive regulation of autophagosome assembly positive regulation of epidermal growth factor receptor signaling pathway positive regulation of protein binding positive regulation of protein phosphorylation positive regulation of protein serine/threonine kinase activity Ras protein signal transduction receptor internalization regulation of exocyst assembly regulation of exocyst localization signal transduction
xenobiotic metabolic process
defense response to bacterium defense response to fungus hydrogen peroxide catabolic process hypochlorous acid biosynthetic process low-density lipoprotein particle remodeling removal of superoxide radicals respiratory burst involved in defense response response to food response to gold nanoparticle response to lipopolysaccharide response to mechanical stimulus response to oxidative stress response to yeast
retrotransposition
membrane fusion involved in viral entry into host cell viral entry into host cell virion attachment to host cell
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell
viral budding via host ESCRT complex
establishment of protein localization to organelle Golgi to lysosome transport granzyme-mediated programmed cell death signaling pathway lysosomal lumen acidification positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein stabilization regulation of organelle transport along microtubule
neuropeptide signaling pathway
viral budding via host ESCRT complex
positive regulation of transcription by RNA polymerase II protein phosphorylation regulation of transcription by RNA polymerase II signal transduction
apoptotic process cell cycle cellular detoxification cellular response to type II interferon negative regulation of apoptotic process negative regulation of DNA-binding transcription factor activity negative regulation of innate immune response positive regulation of brown fat cell differentiation positive regulation of cardiac muscle cell proliferation positive regulation of cardioblast proliferation positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of DNA-templated transcription positive regulation of protein serine/threonine kinase activity positive regulation of TORC1 signaling protein autophosphorylation protein phosphorylation protein stabilization regulation of hematopoietic stem cell proliferation regulation of transmembrane transporter activity vitamin D receptor signaling pathway
cardiac muscle cell differentiation carnitine biosynthetic process carnitine metabolic process, CoA-linked fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase glycogen biosynthetic process liver development medium-chain fatty acid catabolic process medium-chain fatty acid metabolic process post-embryonic development regulation of gluconeogenesis response to cold response to starvation
Group I intron splicing leucyl-tRNA aminoacylation mitochondrial translation mRNA processing
cell population proliferation melanin biosynthetic process pigmentation response to blue light response to cAMP response to UV response to vitamin D thymus development
cellular response to xenobiotic stimulus L-phenylalanine catabolic process liver development response to aluminum ion response to glucagon response to lead ion tetrahydrobiopterin biosynthetic process
anaerobic electron transport chain anaerobic respiration nitrate assimilation nitrate metabolic process
anaerobic electron transport chain anaerobic respiration nitrate assimilation nitrate metabolic process
heme biosynthetic process protoporphyrinogen IX biosynthetic process
acrosome reaction binding of sperm to zona pellucida flagellated sperm motility penetration of zona pellucida positive regulation of protein processing sperm DNA condensation spermatogenesis
photorespiration reductive pentose-phosphate cycle
brain development dentate gyrus development diet induced thermogenesis embryonic digestive tract development hippocampus development intracellular water homeostasis negative regulation of gastrin-induced gastric acid secretion negative regulation of neuron apoptotic process neuron apoptotic process neuronal stem cell population maintenance positive regulation of cAMP-mediated signaling positive regulation of lipid catabolic process positive regulation of pancreatic juice secretion positive regulation of somatostatin secretion regulation of appetite regulation of synaptic plasticity response to nutrient levels visual learning
chromatin remodeling chromosome segregation circadian regulation of gene expression circadian rhythm DNA replication DNA topological change embryonic cleavage peptidyl-serine phosphorylation phosphorylation programmed cell death response to xenobiotic stimulus
brown fat cell differentiation cholesterol homeostasis intracellular lipid transport long-chain fatty acid transport phospholipid homeostasis positive regulation of long-chain fatty acid import into cell positive regulation of phospholipid biosynthetic process regulation of fatty acid oxidation regulation of phosphatidylcholine biosynthetic process
arachidonic acid secretion lipid catabolic process phospholipid metabolic process
glucose metabolic process NADPH regeneration pentose-phosphate shunt, oxidative branch response to hydrogen peroxide
cellular response to oxidative stress cholesterol biosynthetic process erythrocyte maturation glucose 6-phosphate metabolic process glucose metabolic process glutathione metabolic process lipid metabolic process NADP metabolic process NADPH regeneration negative regulation of cell growth involved in cardiac muscle cell development negative regulation of protein glutathionylation negative regulation of reactive oxygen species metabolic process pentose biosynthetic process pentose-phosphate shunt pentose-phosphate shunt, oxidative branch positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel regulation of neuron apoptotic process response to ethanol response to food response to iron(III) ion response to organic cyclic compound ribose phosphate biosynthetic process substantia nigra development
chaeta morphogenesis female sex determination follicle cell of egg chamber development hindgut development Malpighian tubule tip cell differentiation neuroblast fate determination neuroendocrine cell differentiation neuron fate commitment oogenesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II protein stabilization regulation of transcription by RNA polymerase II sensory organ development somatic stem cell population maintenance
cellular bud site selection chemotropism establishment of cell polarity intracellular signal transduction protein localization to cell cortex regulation of exit from mitosis regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion regulation of Rho protein signal transduction septin ring organization
autophagic cell death establishment of protein localization to organelle Golgi to lysosome transport granzyme-mediated programmed cell death signaling pathway lysosomal lumen acidification positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein stabilization regulation of organelle transport along microtubule spermatogenesis
post-translational protein targeting to endoplasmic reticulum membrane protein modification process regulation of protein stability tail-anchored membrane protein insertion into ER membrane ubiquitin-dependent protein catabolic process
de novo' NAD biosynthetic process from aspartate
female pregnancy regulation of immune system process signal transduction
carnitine metabolic process coenzyme A metabolic process fatty acid beta-oxidation fatty acid metabolic process fatty acid transport generation of precursor metabolites and energy long-chain fatty acid transport medium-chain fatty acid metabolic process medium-chain fatty acid transport response to organonitrogen compound response to xenobiotic stimulus
intracellular steroid hormone receptor signaling pathway positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II
cell dedifferentiation cell population proliferation embryonic placenta development in utero embryonic development inner ear development intracellular steroid hormone receptor signaling pathway negative regulation of DNA-templated transcription negative regulation of stem cell differentiation photoreceptor cell maintenance positive regulation of DNA-templated transcription positive regulation of glycogen biosynthetic process positive regulation of glycolytic process positive regulation of stem cell population maintenance positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of stem cell division regulation of transcription by RNA polymerase II somatic stem cell population maintenance stem cell division stem cell population maintenance trophectodermal cell proliferation trophectodermal cellular morphogenesis
antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism innate immune response in mucosa response to xenobiotic stimulus
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulation of smooth muscle contraction regulation of vascular associated smooth muscle contraction saliva secretion
de novo' cotranslational protein folding chaperone cofactor-dependent protein refolding cytoplasmic translation protein refolding regulation of translational fidelity ribosomal subunit export from nucleus rRNA processing translational frameshifting translational termination
carbohydrate metabolic process viral budding from plasma membrane
anatomical structure morphogenesis animal organ morphogenesis cell differentiation cell-cell signaling fibroblast growth factor receptor signaling pathway negative regulation of cardiac muscle tissue development positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulation of protein phosphorylation regulation of cell migration signal transduction
adenylate cyclase-modulating G protein-coupled receptor signaling pathway background adaptation cell population proliferation cellular response to electrical stimulus detection of chemical stimulus involved in sensory perception of bitter taste detection of light stimulus involved in visual perception dopamine secretion eye photoreceptor cell development negative regulation of cyclic-nucleotide phosphodiesterase activity neural tissue regeneration phototransduction, visible light regulation of rhodopsin mediated signaling pathway response to light stimulus response to organic cyclic compound retinal cone cell differentiation retinal rod cell differentiation rhodopsin mediated signaling pathway sensory perception of umami taste signal transduction visual behavior visual perception
dephosphorylation nicotinamide nucleotide metabolic process
cellular response to heat positive regulation of cell cycle G2/M phase transition positive regulation of cell population proliferation positive regulation of nitric oxide biosynthetic process protein folding protein stabilization response to antibiotic response to cold response to heat response to organic cyclic compound response to organonitrogen compound response to progesterone
coumarin catabolic process coumarin metabolic process epoxygenase P450 pathway steroid metabolic process xenobiotic catabolic process xenobiotic metabolic process
androgen catabolic process estrogen biosynthetic process female genitalia development female gonad development mammary gland development negative regulation of chronic inflammatory response negative regulation of macrophage chemotaxis positive regulation of estradiol secretion prostate gland growth response to estradiol steroid biosynthetic process sterol metabolic process syncytium formation testosterone biosynthetic process uterus development
DNA-templated transcription
carbon dioxide transport cellular oxidant detoxification hydrogen peroxide catabolic process nitric oxide transport oxygen transport
autophagy cell death oogenesis positive regulation of transcription by RNA polymerase II regulation of development, heterochronic regulation of transcription by RNA polymerase II salivary gland cell autophagic cell death spermatogenesis
retina development in camera-type eye signal transduction visual perception
cinnamic acid biosynthetic process L-phenylalanine catabolic process
arabinose transmembrane transport fucose metabolic process fucose transmembrane transport galactose transmembrane transport
cytokinetic process
methanogenesis
methanogenesis
methanogenesis
actin filament bundle assembly actin filament capping ATP metabolic process glucose mediated signaling pathway negative regulation of actin filament depolymerization regulation of transcription by RNA polymerase II
10-formyltetrahydrofolate biosynthetic process embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis heart development methionine biosynthetic process methionine metabolic process neural tube closure neutrophil homeostasis one-carbon metabolic process purine nucleotide biosynthetic process purine ribonucleotide biosynthetic process serine family amino acid biosynthetic process serine family amino acid metabolic process somite development tetrahydrofolate interconversion transsulfuration
aerobic respiration cellular response to food cellular response to lipid cellular response to starvation cellular response to testosterone stimulus energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response to glucose stimulus negative regulation of lipid biosynthetic process negative regulation of lipid storage positive regulation of gene expression positive regulation of glucose metabolic process positive regulation of lipid metabolic process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to stilbenoid
aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response to glucose stimulus negative regulation of lipid biosynthetic process negative regulation of lipid storage positive regulation of gene expression positive regulation of glucose metabolic process positive regulation of lipid metabolic process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response to glucose stimulus negative regulation of lipid biosynthetic process negative regulation of lipid storage positive regulation of gene expression positive regulation of glucose metabolic process positive regulation of lipid metabolic process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid homeostasis lipid transport low-density lipoprotein particle remodeling negative regulation of macrophage derived foam cell differentiation phosphatidylcholine metabolic process phospholipid homeostasis positive regulation of cholesterol transport positive regulation of phospholipid transport regulation of cholesterol efflux reverse cholesterol transport triglyceride homeostasis triglyceride metabolic process triglyceride transport very-low-density lipoprotein particle remodeling
adaptive immune response cellular response to interleukin-7 cellular response to nonylphenol cellular response to transforming growth factor beta stimulus cellular response to vitamin D circadian rhythm extrinsic apoptotic signaling pathway peptide antigen assembly with MHC class I protein complex platelet aggregation positive regulation of extrinsic apoptotic signaling pathway positive regulation of protein folding protein folding response to benzene response to endoplasmic reticulum stress response to ethanol response to genistein response to hyperoxia response to hypoxia response to ischemia response to leptin response to nutrient levels
cholesterol homeostasis chylomicron remodeling fatty acid biosynthetic process fatty acid metabolic process low-density lipoprotein particle mediated signaling positive regulation of adipose tissue development positive regulation of chemokine production positive regulation of cholesterol storage positive regulation of fat cell differentiation positive regulation of sequestering of triglyceride triglyceride catabolic process triglyceride homeostasis very-low-density lipoprotein particle remodeling
antigen processing and presentation antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response innate immune response NK T cell differentiation positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of macrophage activation positive regulation of NK T cell activation positive regulation of NK T cell differentiation positive regulation of T cell mediated cytotoxicity positive regulation of T cell proliferation positive regulation of type II interferon production positive thymic T cell selection regulation of immature T cell proliferation in thymus regulation of immune response
antigen processing and presentation, endogenous lipid antigen via MHC class Ib antigen processing and presentation, exogenous lipid antigen via MHC class Ib immune response innate immune response positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of NK T cell activation positive regulation of T cell mediated cytotoxicity positive regulation of T cell proliferation
angiogenesis calcium-mediated signaling cell adhesion cell chemotaxis immune response negative regulation of cell population proliferation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage oculomotor nerve development positive regulation of cytosolic calcium ion concentration positive regulation of ERK1 and ERK2 cascade receptor internalization vasculogenesis
adenylate cyclase-activating G protein-coupled receptor signaling pathway apoptotic signaling pathway eating behavior G protein-coupled adenosine receptor signaling pathway inhibitory postsynaptic potential locomotory behavior negative regulation of alpha-beta T cell activation negative regulation of inflammatory response positive regulation of apoptotic signaling pathway positive regulation of synaptic transmission, GABAergic response to amphetamine response to inorganic substance response to purine-containing compound synaptic transmission, dopaminergic
autophagosome assembly endoplasmic reticulum to Golgi vesicle-mediated transport intracellular protein transport
chromatin organization chromatin remodeling DNA repair maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III negative regulation of DNA binding protein-DNA complex assembly RNA polymerase II preinitiation complex assembly RNA polymerase III preinitiation complex assembly
chromatin remodeling DNA repair maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III RNA polymerase III preinitiation complex assembly transcription by RNA polymerase II
protein secretion regulation of COPII vesicle coating vesicle-mediated transport
amino acid transport L-arginine transmembrane transport
cellular response to hydrogen peroxide defense response to bacterium extrinsic apoptotic signaling pathway in absence of ligand innate immune response long-term memory negative regulation of hippocampal neuron apoptotic process positive regulation of apoptotic process positive regulation of cell projection organization positive regulation of cold-induced thermogenesis positive regulation of endothelial cell migration positive regulation of endothelial tube morphogenesis positive regulation of gene expression positive regulation of hippocampal neuron apoptotic process positive regulation of iron ion import across plasma membrane positive regulation of neuron apoptotic process positive regulation of reactive oxygen species biosynthetic process positive regulation of reactive oxygen species metabolic process response to bacterium response to herbicide response to virus response to xenobiotic stimulus short-term memory siderophore transport