JuIm/Molecular_Function · Datasets at Hugging Face

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GDP binding GTP binding GTPase activity protein-containing complex binding
ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ATP-dependent chromatin remodeler activity chromatin binding DNA binding helicase activity ubiquitin binding
PDZ domain binding structural constituent of postsynaptic density transmembrane transporter binding
amyloid-beta binding AP-1 adaptor complex binding AP-2 adaptor complex binding clathrin adaptor activity clathrin binding low-density lipoprotein particle receptor binding phosphatidylinositol-4,5-bisphosphate binding phosphotyrosine residue binding signaling adaptor activity signaling receptor complex adaptor activity
phosphatidylserine decarboxylase activity
guanyl-nucleotide exchange factor activity kinase binding phosphotyrosine residue binding
ATP binding metal ion binding molecular function activator activity protein serine kinase activity protein serine/threonine kinase activity
chromatin DNA binding DNA binding double-stranded DNA binding histone deacetylase binding nucleosomal DNA binding structural constituent of chromatin
ABC-type sterol transporter activity ATP binding ATP hydrolysis activity identical protein binding protein heterodimerization activity protein homodimerization activity
cytoskeletal protein binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity
ATP binding ubiquitin conjugating enzyme activity ubiquitin protein ligase activity ubiquitin protein ligase binding ubiquitin-protein transferase activity
ADP phosphatase activity glycerol-1-phosphatase activity glycerol-3-phosphatase activity magnesium ion binding phosphoglycolate phosphatase activity protein tyrosine phosphatase activity
AP-1 adaptor complex binding AP-2 adaptor complex binding DNA binding double-stranded RNA binding nucleic acid transmembrane transporter activity RNA transmembrane transporter activity
actin filament binding actinin binding filamin binding metal ion binding small GTPase binding
structural constituent of eye lens
ATP binding ATP-dependent diacylglycerol kinase activity DNA-binding transcription factor binding kinase binding metal ion binding phospholipase binding transmembrane receptor protein tyrosine kinase activator activity
alditol:NADP+ 1-oxidoreductase activity aldo-keto reductase (NADP) activity farnesol dehydrogenase activity ketosteroid monooxygenase activity steroid dehydrogenase activity
SH3 domain binding syntaxin-1 binding
GTPase activator activity semaphorin receptor binding SH3 domain binding
ATP binding bHLH transcription factor binding JUN kinase kinase kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity transcription corepressor activity
ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity
GTPase activator activity inositol phosphate phosphatase activity inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity inositol-1,4,5-trisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity small GTPase binding
ATP binding protein serine kinase activity protein serine/threonine kinase activity
ABC-type fatty-acyl-CoA transporter activity acyl-CoA hydrolase activity ADP binding ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity enzyme binding identical protein binding long-chain fatty acid transporter activity protein heterodimerization activity protein homodimerization activity
chromatin binding chromatin DNA binding cysteine-type deubiquitinase activity histone H2A deubiquitinase activity
1-acylglycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity
acetylcholine receptor binding ubiquitin binding
lipid binding protein-containing complex binding
antiporter activity L-aspartate transmembrane transporter activity L-glutamine transmembrane transporter activity L-serine transmembrane transporter activity ligand-gated channel activity metal ion binding neutral L-amino acid transmembrane transporter activity symporter activity
identical protein binding potassium:proton antiporter activity sodium:proton antiporter activity
2-oxoglutarate-dependent dioxygenase activity metal ion binding molecular condensate scaffold activity mRNA N6-methyladenosine dioxygenase activity oxidative RNA demethylase activity
hepoxilin A3 synthase activity hydroperoxy icosatetraenoate dehydratase activity hydroperoxy icosatetraenoate isomerase activity intramolecular hydroxytransferase activity iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding
ATP binding ATPase binding magnesium ion binding protein kinase binding protein serine kinase activity protein serine/threonine kinase activity tau-protein kinase activity
arginine binding basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-arginine transmembrane transporter activity L-lysine:L-arginine antiporter activity
5'-nucleotidase activity ATP binding GMP 5'-nucleotidase activity identical protein binding IMP 5'-nucleotidase activity metal ion binding nucleoside phosphotransferase activity ubiquitin protein ligase activity
cysteine-type deubiquitinase activity cysteine-type endopeptidase activity
Hsp90 protein binding identical protein binding
arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity
identical protein binding metal ion binding phosphatidic acid binding small GTPase binding
GTPase activity magnesium ion binding microtubule binding microtubule nucleator activity protein dimerization activity protein homodimerization activity tubulin binding
kinesin binding
calcium-independent phospholipase A2 activity lysophospholipase activity phosphatidyl phospholipase B activity phospholipase A1 activity
lipid binding metal ion binding metalloendopeptidase activity
1-phosphatidylinositol-4-phosphate 5-kinase activity ATP binding kinase binding
ATP binding DNA-binding transcription factor binding magnesium ion binding MAP kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity SH2 domain binding ubiquitin protein ligase binding
calcium ion binding peptidase activity serine-type endopeptidase activity
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding
acetylcholine receptor inhibitor activity acetylcholine receptor regulator activity
chemorepellent activity fibroblast growth factor receptor binding
2-oxoglutarate-dependent dioxygenase activity histone H3K36 demethylase activity histone H3K36me/H3K36me2 demethylase activity histone H3K4 demethylase activity histone H3K4me/H3K4me2/H3K4me3 demethylase activity iron ion binding peptidyl-histidine dioxygenase activity protein demethylase activity
methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity
actin filament binding cytoskeletal anchor activity G-protein alpha-subunit binding microtubule binding
NAD(P)+ nucleosidase activity NAD+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating signaling adaptor activity
dynein light intermediate chain binding protein dimerization activity small GTPase binding
ATP binding ATP hydrolysis activity chromatin binding enzyme binding helicase activity MutLbeta complex binding MutSalpha complex binding MutSbeta complex binding single-stranded DNA binding
miRNA binding translation repressor activity ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding
double-stranded DNA binding K63-linked polyubiquitin modification-dependent protein binding metal ion binding metalloendopeptidase activity polyubiquitin modification-dependent protein binding single-stranded DNA binding ubiquitin binding
aspartate N-acetyltransferase activity
RNA binding
dITP diphosphatase activity identical protein binding ITP diphosphatase activity metal ion binding nucleoside triphosphate diphosphatase activity nucleotide binding XTP diphosphatase activity
chromatin binding histone binding identical protein binding methylated histone binding nucleosome binding SAM domain binding zinc ion binding
identical protein binding phosphatidylinositol binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylserine binding
14-3-3 protein binding ubiquitin ligase-substrate adaptor activity
high voltage-gated calcium channel activity protein kinase binding voltage-gated calcium channel activity voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
3-hydroxybutyrate dehydrogenase activity 4-oxoproline reductase activity NAD binding oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
calcium ion binding calcium-dependent phospholipid binding endopeptidase activity identical protein binding NF-kappaB binding phosphatidylserine binding
apolipoprotein binding ceramide 1-phosphate transfer activity cholesterol transfer activity lipid binding lipid transporter activity phosphatidylcholine transfer activity phosphatidylethanolamine transfer activity phospholipid transfer activity phospholipid transporter activity protein heterodimerization activity protein-containing complex binding triglyceride transfer activity
ATP binding protein serine kinase activity protein serine/threonine kinase activity
pyridoxal phosphate binding serine C-palmitoyltransferase activity
chromatin DNA binding DNA binding double-stranded DNA binding heparin binding nucleosomal DNA binding structural constituent of chromatin
cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding
GTPase binding phosphatidylinositol 3-kinase inhibitor activity protein-membrane adaptor activity
acyltransferase activity, transferring groups other than amino-acyl groups fatty acid elongase activity
catalytic activity ornithine decarboxylase activator activity
creatine transmembrane transporter activity monocarboxylic acid transmembrane transporter activity uniporter activity
DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding
potassium:proton antiporter activity sodium:proton antiporter activity
G protein-coupled receptor activity oxysterol binding
neurexin family protein binding
histone binding histone reader activity lysine-acetylated histone binding
hormone activity identical protein binding
calcium ion binding
3'-5' DNA helicase activity ATP binding ATP hydrolysis activity DNA helicase activity four-way junction helicase activity helicase activity nucleic acid binding RNA polymerase II complex binding
3'(2'),5'-bisphosphate nucleotidase activity 3',5'-nucleotide bisphosphate phosphatase activity 3'-nucleotidase activity metal ion binding
delayed rectifier potassium channel activity
fatty acid elongase activity
GTP binding GTPase activity
inorganic diphosphate phosphatase activity magnesium ion binding
malate synthase activity metal ion binding
glycosyltransferase activity
ATP binding ATP hydrolysis activity
endopeptidase activity threonine-type endopeptidase activity
cellulose 1,4-beta-cellobiosidase activity
haloalkane dehalogenase activity
electron transfer activity heme binding metal ion binding
cobalt ion transmembrane transporter activity
beta-glucosidase activity DIMBOA glucoside beta-D-glucosidase activity scopolin beta-glucosidase activity
metal ion binding sphingomyelin phosphodiesterase activity
metal ion binding metalloendopeptidase activity toxin activity

GDP binding GTP binding GTPase activity protein-containing complex binding

ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ATP-dependent chromatin remodeler activity chromatin binding DNA binding helicase activity ubiquitin binding

PDZ domain binding structural constituent of postsynaptic density transmembrane transporter binding

amyloid-beta binding AP-1 adaptor complex binding AP-2 adaptor complex binding clathrin adaptor activity clathrin binding low-density lipoprotein particle receptor binding phosphatidylinositol-4,5-bisphosphate binding phosphotyrosine residue binding signaling adaptor activity signaling receptor complex adaptor activity

phosphatidylserine decarboxylase activity

guanyl-nucleotide exchange factor activity kinase binding phosphotyrosine residue binding

ATP binding metal ion binding molecular function activator activity protein serine kinase activity protein serine/threonine kinase activity

chromatin DNA binding DNA binding double-stranded DNA binding histone deacetylase binding nucleosomal DNA binding structural constituent of chromatin

ABC-type sterol transporter activity ATP binding ATP hydrolysis activity identical protein binding protein heterodimerization activity protein homodimerization activity

cytoskeletal protein binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity

ATP binding ubiquitin conjugating enzyme activity ubiquitin protein ligase activity ubiquitin protein ligase binding ubiquitin-protein transferase activity

ADP phosphatase activity glycerol-1-phosphatase activity glycerol-3-phosphatase activity magnesium ion binding phosphoglycolate phosphatase activity protein tyrosine phosphatase activity

AP-1 adaptor complex binding AP-2 adaptor complex binding DNA binding double-stranded RNA binding nucleic acid transmembrane transporter activity RNA transmembrane transporter activity

actin filament binding actinin binding filamin binding metal ion binding small GTPase binding

structural constituent of eye lens

ATP binding ATP-dependent diacylglycerol kinase activity DNA-binding transcription factor binding kinase binding metal ion binding phospholipase binding transmembrane receptor protein tyrosine kinase activator activity

alditol:NADP+ 1-oxidoreductase activity aldo-keto reductase (NADP) activity farnesol dehydrogenase activity ketosteroid monooxygenase activity steroid dehydrogenase activity

SH3 domain binding syntaxin-1 binding

GTPase activator activity semaphorin receptor binding SH3 domain binding

ATP binding bHLH transcription factor binding JUN kinase kinase kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity transcription corepressor activity

ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity

GTPase activator activity inositol phosphate phosphatase activity inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity inositol-1,4,5-trisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity small GTPase binding

ATP binding protein serine kinase activity protein serine/threonine kinase activity

ABC-type fatty-acyl-CoA transporter activity acyl-CoA hydrolase activity ADP binding ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity enzyme binding identical protein binding long-chain fatty acid transporter activity protein heterodimerization activity protein homodimerization activity

chromatin binding chromatin DNA binding cysteine-type deubiquitinase activity histone H2A deubiquitinase activity

1-acylglycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity

acetylcholine receptor binding ubiquitin binding

lipid binding protein-containing complex binding

antiporter activity L-aspartate transmembrane transporter activity L-glutamine transmembrane transporter activity L-serine transmembrane transporter activity ligand-gated channel activity metal ion binding neutral L-amino acid transmembrane transporter activity symporter activity

identical protein binding potassium:proton antiporter activity sodium:proton antiporter activity

2-oxoglutarate-dependent dioxygenase activity metal ion binding molecular condensate scaffold activity mRNA N6-methyladenosine dioxygenase activity oxidative RNA demethylase activity

hepoxilin A3 synthase activity hydroperoxy icosatetraenoate dehydratase activity hydroperoxy icosatetraenoate isomerase activity intramolecular hydroxytransferase activity iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding

ATP binding ATPase binding magnesium ion binding protein kinase binding protein serine kinase activity protein serine/threonine kinase activity tau-protein kinase activity

arginine binding basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-arginine transmembrane transporter activity L-lysine:L-arginine antiporter activity

5'-nucleotidase activity ATP binding GMP 5'-nucleotidase activity identical protein binding IMP 5'-nucleotidase activity metal ion binding nucleoside phosphotransferase activity ubiquitin protein ligase activity

cysteine-type deubiquitinase activity cysteine-type endopeptidase activity

Hsp90 protein binding identical protein binding

arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity

identical protein binding metal ion binding phosphatidic acid binding small GTPase binding

GTPase activity magnesium ion binding microtubule binding microtubule nucleator activity protein dimerization activity protein homodimerization activity tubulin binding

kinesin binding

calcium-independent phospholipase A2 activity lysophospholipase activity phosphatidyl phospholipase B activity phospholipase A1 activity

lipid binding metal ion binding metalloendopeptidase activity

1-phosphatidylinositol-4-phosphate 5-kinase activity ATP binding kinase binding

ATP binding DNA-binding transcription factor binding magnesium ion binding MAP kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity SH2 domain binding ubiquitin protein ligase binding

calcium ion binding peptidase activity serine-type endopeptidase activity

DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding

acetylcholine receptor inhibitor activity acetylcholine receptor regulator activity

chemorepellent activity fibroblast growth factor receptor binding

2-oxoglutarate-dependent dioxygenase activity histone H3K36 demethylase activity histone H3K36me/H3K36me2 demethylase activity histone H3K4 demethylase activity histone H3K4me/H3K4me2/H3K4me3 demethylase activity iron ion binding peptidyl-histidine dioxygenase activity protein demethylase activity

methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity

actin filament binding cytoskeletal anchor activity G-protein alpha-subunit binding microtubule binding

NAD(P)+ nucleosidase activity NAD+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating signaling adaptor activity

dynein light intermediate chain binding protein dimerization activity small GTPase binding

ATP binding ATP hydrolysis activity chromatin binding enzyme binding helicase activity MutLbeta complex binding MutSalpha complex binding MutSbeta complex binding single-stranded DNA binding

miRNA binding translation repressor activity ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding

double-stranded DNA binding K63-linked polyubiquitin modification-dependent protein binding metal ion binding metalloendopeptidase activity polyubiquitin modification-dependent protein binding single-stranded DNA binding ubiquitin binding

aspartate N-acetyltransferase activity

RNA binding

dITP diphosphatase activity identical protein binding ITP diphosphatase activity metal ion binding nucleoside triphosphate diphosphatase activity nucleotide binding XTP diphosphatase activity

chromatin binding histone binding identical protein binding methylated histone binding nucleosome binding SAM domain binding zinc ion binding

identical protein binding phosphatidylinositol binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylserine binding

14-3-3 protein binding ubiquitin ligase-substrate adaptor activity

high voltage-gated calcium channel activity protein kinase binding voltage-gated calcium channel activity voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

3-hydroxybutyrate dehydrogenase activity 4-oxoproline reductase activity NAD binding oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

calcium ion binding calcium-dependent phospholipid binding endopeptidase activity identical protein binding NF-kappaB binding phosphatidylserine binding

apolipoprotein binding ceramide 1-phosphate transfer activity cholesterol transfer activity lipid binding lipid transporter activity phosphatidylcholine transfer activity phosphatidylethanolamine transfer activity phospholipid transfer activity phospholipid transporter activity protein heterodimerization activity protein-containing complex binding triglyceride transfer activity

ATP binding protein serine kinase activity protein serine/threonine kinase activity

pyridoxal phosphate binding serine C-palmitoyltransferase activity

chromatin DNA binding DNA binding double-stranded DNA binding heparin binding nucleosomal DNA binding structural constituent of chromatin

cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding

GTPase binding phosphatidylinositol 3-kinase inhibitor activity protein-membrane adaptor activity

acyltransferase activity, transferring groups other than amino-acyl groups fatty acid elongase activity

catalytic activity ornithine decarboxylase activator activity

creatine transmembrane transporter activity monocarboxylic acid transmembrane transporter activity uniporter activity

DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding

potassium:proton antiporter activity sodium:proton antiporter activity

G protein-coupled receptor activity oxysterol binding

neurexin family protein binding

histone binding histone reader activity lysine-acetylated histone binding

hormone activity identical protein binding

calcium ion binding

3'-5' DNA helicase activity ATP binding ATP hydrolysis activity DNA helicase activity four-way junction helicase activity helicase activity nucleic acid binding RNA polymerase II complex binding

3'(2'),5'-bisphosphate nucleotidase activity 3',5'-nucleotide bisphosphate phosphatase activity 3'-nucleotidase activity metal ion binding

delayed rectifier potassium channel activity

fatty acid elongase activity

GTP binding GTPase activity

inorganic diphosphate phosphatase activity magnesium ion binding

malate synthase activity metal ion binding

glycosyltransferase activity

ATP binding ATP hydrolysis activity

endopeptidase activity threonine-type endopeptidase activity

cellulose 1,4-beta-cellobiosidase activity

haloalkane dehalogenase activity

electron transfer activity heme binding metal ion binding

cobalt ion transmembrane transporter activity

beta-glucosidase activity DIMBOA glucoside beta-D-glucosidase activity scopolin beta-glucosidase activity

metal ion binding sphingomyelin phosphodiesterase activity

metal ion binding metalloendopeptidase activity toxin activity