Biological Process
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| Organism
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| Keywords
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calcium-mediated signaling endocytosis involved in viral entry into host cell regulation of myotome development skeletal myofibril assembly smooth muscle contraction sodium ion transmembrane transport | late endosome membrane; lysosomal membrane; lysosome; monoatomic ion channel complex | identical protein binding intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity ligand-gated sodium channel activity NAADP-sensitive calcium-release channel activity phosphatidylinositol-3,5-bisphosphate binding voltage-gated calcium channel activity | Danio rerio | Calcium Calcium channel Calcium transport Endosome Glycoprotein Ion channel Ion transport Lysosome Membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport Voltage-gated channel | MEEEPLLAGS | MEEEPLLAGSINQGSGDYGAHSESCLHYPDEHTPRSRRLSYSVTDDSCNVEEDADADLYVQQAVVFIEDAIKYRSINHRVDSGSLRLYRWYYSNLCQWGLGLTIAVVLALAFIERPSSLTYTSDIRVKPKPWEPPCGMTEGIEIVCLCIFILDVTAKGYLIGWEEFRMNKWLLAYLIVITASVIDWMLSISMLCDENLRVRRLIRPFFLLQNSSLMKKTLKCIKRTLPEIASVILLLALHICLFTMIGMLIFAKSDDPKQNGEWQTYFRNLPKALSSLLVLLTTANNPDVMIPAYSLNRGYSIFFILFSVFGTYLLMNLMTAIIYNQFRGYLLMSVQTSIIRRRLGIRAAFEVLCCPGRGHTSTQAEGHVERVAVSMFLKVMERVHMKSYCRQAIVKAARRFPDGFISGEDFQRLFNELDKDFVKEHPPKPEYSSSGLQHIQYVYSHYYISVLGNAVALANVICICTVLVLNAEKSASEKNYFYMEIINCIFILYYLIEMLLKIVAFGWKGYLSYRNNIFDGFLTVLLLAIQIVIFITFKIPYVDVDPVPRHVMALWEMIRLVNMLIVFRFLRIIPEIKLMAVVASTIVDLVKNLRAFAGILLVVYYMFAVLGIWLFQGAISPPSNMSLVSNSSLENITGPYSMECGTFEQLEYWPNNFDDFASSLILLYNIMVVNNWHVFTDAYARYTTDWSLVYFVVWWLTSSVMWVNLFVALILENFTYKWDRSNGLSVEDVERIAYQSTVQLMFKEHVKEPTEEELLAQLHQHPHLHLSW | calcium-mediated signaling endocytosis involved in viral entry into host cell regulation of myotome development skeletal myofibril assembly smooth muscle contraction sodium ion transmembrane transport late endosome membrane; lysosomal membrane; lysosome; monoatomic ion channel complex identical protein binding intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity ligand-gated sodium channel activity NAADP-sensitive calcium-release channel activity phosphatidylinositol-3,5-bisphosphate binding voltage-gated calcium channel activity Danio rerio Calcium Calcium channel Calcium transport Endosome Glycoprotein Ion channel Ion transport Lysosome Membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport Voltage-gated channel MEEEPLLAGS MEEEPLLAGSINQGSGDYGAHSESCLHYPDEHTPRSRRLSYSVTDDSCNVEEDADADLYVQQAVVFIEDAIKYRSINHRVDSGSLRLYRWYYSNLCQWGLGLTIAVVLALAFIERPSSLTYTSDIRVKPKPWEPPCGMTEGIEIVCLCIFILDVTAKGYLIGWEEFRMNKWLLAYLIVITASVIDWMLSISMLCDENLRVRRLIRPFFLLQNSSLMKKTLKCIKRTLPEIASVILLLALHICLFTMIGMLIFAKSDDPKQNGEWQTYFRNLPKALSSLLVLLTTANNPDVMIPAYSLNRGYSIFFILFSVFGTYLLMNLMTAIIYNQFRGYLLMSVQTSIIRRRLGIRAAFEVLCCPGRGHTSTQAEGHVERVAVSMFLKVMERVHMKSYCRQAIVKAARRFPDGFISGEDFQRLFNELDKDFVKEHPPKPEYSSSGLQHIQYVYSHYYISVLGNAVALANVICICTVLVLNAEKSASEKNYFYMEIINCIFILYYLIEMLLKIVAFGWKGYLSYRNNIFDGFLTVLLLAIQIVIFITFKIPYVDVDPVPRHVMALWEMIRLVNMLIVFRFLRIIPEIKLMAVVASTIVDLVKNLRAFAGILLVVYYMFAVLGIWLFQGAISPPSNMSLVSNSSLENITGPYSMECGTFEQLEYWPNNFDDFASSLILLYNIMVVNNWHVFTDAYARYTTDWSLVYFVVWWLTSSVMWVNLFVALILENFTYKWDRSNGLSVEDVERIAYQSTVQLMFKEHVKEPTEEELLAQLHQHPHLHLSW |
brain development cell migration central nervous system morphogenesis cytoskeleton organization positive regulation of Wnt signaling pathway protein K29-linked deubiquitination protein K33-linked deubiquitination protein K63-linked deubiquitination proteolysis regulation of cell morphogenesis Wnt signaling pathway | cytoplasm; nucleus | cysteine-type deubiquitinase activity K63-linked polyubiquitin modification-dependent protein binding metal ion binding | Danio rerio | ANK repeat Cytoplasm Hydrolase Metal-binding Nucleus Protease Reference proteome Repeat Thiol protease Ubl conjugation pathway Wnt signaling pathway Zinc Zinc-finger | MTDLGLKWSC | MTDLGLKWSCEYCTYENWPSAIKCTMCRAQRHNAPIITEEPFKSSSSLDPSLCTTQGGSTLLICPDSSARPRVRIADELPETSSKWSCHMCTYLNWPRAIRCTQCLSQRQQGSQQHSPLSPSETPQTSGSRPSPVTSDPCEEYNDRNRLNMHAQRWPCSACTYENWPKSLRCVVCDHPKPSGSPETPQQDSEAESATSPSIVNEQERENVRTAGGGGGGSRGRLRKLSPPMCKGQAEVKIELASGAVGSDNEQEADFKKLKQIRNRMRRSDWLFLNACAGVVEGDLAAVEAYKSSGGDIARQLTADEVRILNRPSAFDAGFTLVHLAIRFQRQDMLAVLLTEVSQQTAKCIPALVCPELTEQIRREVAAALHRRKGEFPCYFFTDLVTFTLPADIEDLPPNVQEKLFDEVLDRDVQKELEEESPIINWSLELGTRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKSLNDSLHDCSHWFYTRWKEWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHVFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYDNRGAGANLNTDDDVTVTFLPLVDSERKLLHIHFLSAQEMGTEEQQERMLRQWMDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDGYRQLAACPTLSDGEEEEEDEDE | brain development cell migration central nervous system morphogenesis cytoskeleton organization positive regulation of Wnt signaling pathway protein K29-linked deubiquitination protein K33-linked deubiquitination protein K63-linked deubiquitination proteolysis regulation of cell morphogenesis Wnt signaling pathway cytoplasm; nucleus cysteine-type deubiquitinase activity K63-linked polyubiquitin modification-dependent protein binding metal ion binding Danio rerio ANK repeat Cytoplasm Hydrolase Metal-binding Nucleus Protease Reference proteome Repeat Thiol protease Ubl conjugation pathway Wnt signaling pathway Zinc Zinc-finger MTDLGLKWSC MTDLGLKWSCEYCTYENWPSAIKCTMCRAQRHNAPIITEEPFKSSSSLDPSLCTTQGGSTLLICPDSSARPRVRIADELPETSSKWSCHMCTYLNWPRAIRCTQCLSQRQQGSQQHSPLSPSETPQTSGSRPSPVTSDPCEEYNDRNRLNMHAQRWPCSACTYENWPKSLRCVVCDHPKPSGSPETPQQDSEAESATSPSIVNEQERENVRTAGGGGGGSRGRLRKLSPPMCKGQAEVKIELASGAVGSDNEQEADFKKLKQIRNRMRRSDWLFLNACAGVVEGDLAAVEAYKSSGGDIARQLTADEVRILNRPSAFDAGFTLVHLAIRFQRQDMLAVLLTEVSQQTAKCIPALVCPELTEQIRREVAAALHRRKGEFPCYFFTDLVTFTLPADIEDLPPNVQEKLFDEVLDRDVQKELEEESPIINWSLELGTRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKSLNDSLHDCSHWFYTRWKEWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHVFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYDNRGAGANLNTDDDVTVTFLPLVDSERKLLHIHFLSAQEMGTEEQQERMLRQWMDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDGYRQLAACPTLSDGEEEEEDEDE |
diacylglycerol metabolic process intracellular signal transduction lipid phosphorylation phosphatidic acid biosynthetic process protein kinase C-activating G protein-coupled receptor signaling pathway | cytosol; plasma membrane | alkylglycerol kinase activity ATP binding ATP-dependent diacylglycerol kinase activity calcium ion binding | Bos taurus | Acetylation ATP-binding Calcium Cytoplasm Kinase Lipid metabolism Metal-binding Nucleotide-binding Reference proteome Repeat Transferase Zinc Zinc-finger | MAKERGLISP | MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAEYLQGDAIGYEGFQQFLKIYLEVDNVPDHLSQALFQSFQTGYYIEDTVREDVVCLSDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDRIIIQMMRMAEYLDWDVSELRPILQEMMKEIDYDGSGSVSLAEWLRAGATTVPLLVLLGLEMTLKDNGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYIVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLVGLHCVWCHLEIHDDCLPAMGHECDCGLLRDHILPPSSIYPSVLASGQERKTSKISQKTMDDLSLSTSEALRIDPVSNTHPLLVFVNPKSGGKQGERVLWKFQYLLNPRQVFNLLKDGPEPGLRFFRDVPDYRILVCGGDGTVGWILESIDKANLPFVPPVAVLPLGTGNDLARCLRWGGGYEGQNLGKILKDLETSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVLNIPSTHGGSNLWGDTKRPHGDIHGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLEGAIEIGQIYTKLKNAGHRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHRNQMPMLVGPPPRSSNFFGFLC | diacylglycerol metabolic process intracellular signal transduction lipid phosphorylation phosphatidic acid biosynthetic process protein kinase C-activating G protein-coupled receptor signaling pathway cytosol; plasma membrane alkylglycerol kinase activity ATP binding ATP-dependent diacylglycerol kinase activity calcium ion binding Bos taurus Acetylation ATP-binding Calcium Cytoplasm Kinase Lipid metabolism Metal-binding Nucleotide-binding Reference proteome Repeat Transferase Zinc Zinc-finger MAKERGLISP MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAEYLQGDAIGYEGFQQFLKIYLEVDNVPDHLSQALFQSFQTGYYIEDTVREDVVCLSDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDRIIIQMMRMAEYLDWDVSELRPILQEMMKEIDYDGSGSVSLAEWLRAGATTVPLLVLLGLEMTLKDNGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYIVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLVGLHCVWCHLEIHDDCLPAMGHECDCGLLRDHILPPSSIYPSVLASGQERKTSKISQKTMDDLSLSTSEALRIDPVSNTHPLLVFVNPKSGGKQGERVLWKFQYLLNPRQVFNLLKDGPEPGLRFFRDVPDYRILVCGGDGTVGWILESIDKANLPFVPPVAVLPLGTGNDLARCLRWGGGYEGQNLGKILKDLETSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVLNIPSTHGGSNLWGDTKRPHGDIHGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLEGAIEIGQIYTKLKNAGHRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHRNQMPMLVGPPPRSSNFFGFLC |
CDP-diacylglycerol biosynthetic process lipid droplet formation | endoplasmic reticulum; endoplasmic reticulum membrane; membrane | phosphatidate cytidylyltransferase activity | Bos taurus | Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane Nucleotidyltransferase Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix | MTELRQRVAR | MTELRQRVAREPEAPPEDKESESEAKADGETASDSESRVEAVTQPPSADDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMMIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSGLFRLQEYNIPGVIQSIIGWKTVRMYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGPNPSKLVQQFLTLRPDQQLHIFNTLKSHLTDKGMLTAATEDK | CDP-diacylglycerol biosynthetic process lipid droplet formation endoplasmic reticulum; endoplasmic reticulum membrane; membrane phosphatidate cytidylyltransferase activity Bos taurus Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane Nucleotidyltransferase Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix MTELRQRVAR MTELRQRVAREPEAPPEDKESESEAKADGETASDSESRVEAVTQPPSADDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMMIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSGLFRLQEYNIPGVIQSIIGWKTVRMYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGPNPSKLVQQFLTLRPDQQLHIFNTLKSHLTDKGMLTAATEDK |
cellular response to insulin stimulus cholesterol biosynthetic process cholesterol homeostasis cranial suture morphogenesis inner ear morphogenesis middle ear morphogenesis negative regulation of cargo loading into COPII-coated vesicle negative regulation of fat cell differentiation negative regulation of fatty acid biosynthetic process negative regulation of protein exit from endoplasmic reticulum negative regulation of steroid biosynthetic process roof of mouth development SREBP signaling pathway SREBP-SCAP complex retention in endoplasmic reticulum triglyceride metabolic process | endoplasmic reticulum; SREBP-SCAP-Insig complex | oxysterol binding protein sequestering activity | Bos taurus | Cholesterol metabolism Endoplasmic reticulum Isopeptide bond Lipid metabolism Lipid-binding Membrane Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism Transmembrane Transmembrane helix Ubl conjugation | MPRLDDHLWR | MPRLDDHLWRGPCAKGTKHRSHPRASARGLVAKAGEMINSSGSGPSLLAAHGALGTDPAHGPQSAGVGGQGSSSHVNSWHHHLVQRSLVLFSVGVVLALVLNLLQVQRNVTLFPDEVIATIFSSAWWVPPCCGTAAAVVGLLYPCIDSHLGEPHKFKREWASVMRCVAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQLLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAMGVPEKPHSD | cellular response to insulin stimulus cholesterol biosynthetic process cholesterol homeostasis cranial suture morphogenesis inner ear morphogenesis middle ear morphogenesis negative regulation of cargo loading into COPII-coated vesicle negative regulation of fat cell differentiation negative regulation of fatty acid biosynthetic process negative regulation of protein exit from endoplasmic reticulum negative regulation of steroid biosynthetic process roof of mouth development SREBP signaling pathway SREBP-SCAP complex retention in endoplasmic reticulum triglyceride metabolic process endoplasmic reticulum; SREBP-SCAP-Insig complex oxysterol binding protein sequestering activity Bos taurus Cholesterol metabolism Endoplasmic reticulum Isopeptide bond Lipid metabolism Lipid-binding Membrane Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism Transmembrane Transmembrane helix Ubl conjugation MPRLDDHLWR MPRLDDHLWRGPCAKGTKHRSHPRASARGLVAKAGEMINSSGSGPSLLAAHGALGTDPAHGPQSAGVGGQGSSSHVNSWHHHLVQRSLVLFSVGVVLALVLNLLQVQRNVTLFPDEVIATIFSSAWWVPPCCGTAAAVVGLLYPCIDSHLGEPHKFKREWASVMRCVAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQLLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAMGVPEKPHSD |
fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid long-chain fatty-acyl-CoA biosynthetic process sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process very long-chain fatty acid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane | fatty acid elongase activity | Bos taurus | Acetylation Disulfide bond Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MAFSDLTSRT | MAFSDLTSRTVRLYDNWIKDADPRVEDWLLMSSPLPQTIILGFYVYFVTSLGPKLMENRKPFELKKVMITYNFSIVLFSVYMFYEFIMSGWGTGYSFRCDIVDYSQSPTALRMVRTCWLYYFSKFIELLDTIFFILRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHAFLNTAVHVVMYSYYGLCALGPDYQKYLWWKKYLTSLQLIQFVLITIHISQFFFMEDCKYQFPVFQYIIMSYGCIFLLLFLHFWYRAYTKGQRLPKTVKHGICKNKDH | fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid long-chain fatty-acyl-CoA biosynthetic process sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process very long-chain fatty acid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane fatty acid elongase activity Bos taurus Acetylation Disulfide bond Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Reference proteome Transferase Transmembrane Transmembrane helix MAFSDLTSRT MAFSDLTSRTVRLYDNWIKDADPRVEDWLLMSSPLPQTIILGFYVYFVTSLGPKLMENRKPFELKKVMITYNFSIVLFSVYMFYEFIMSGWGTGYSFRCDIVDYSQSPTALRMVRTCWLYYFSKFIELLDTIFFILRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHAFLNTAVHVVMYSYYGLCALGPDYQKYLWWKKYLTSLQLIQFVLITIHISQFFFMEDCKYQFPVFQYIIMSYGCIFLLLFLHFWYRAYTKGQRLPKTVKHGICKNKDH |
DNA damage response DNA repair-dependent chromatin remodeling double-strand break repair double-strand break repair via nonhomologous end joining embryo implantation regulation of epithelial to mesenchymal transition single strand break repair | cytosol; nucleus; site of DNA damage; site of double-strand break | 3'-5' exonuclease activity ADP-D-ribose modification-dependent protein binding DNA endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity histone binding histone chaperone activity metal ion binding nucleotide binding poly-ADP-D-ribose binding | Bos taurus | ADP-ribosylation Chromosome Coiled coil Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Zinc Zinc-finger | MSGGFELQPQ | MSGGFELQPQDGGPRVALAPGETVIGRGPLLGLHRNPCYYQSSEKSQLLPLKTNIWCWLNPGDHFSLLVDKYIFCVLSTHSEMEMECTLRNSQMLDEDDILNEIPKSSSADLPDKTPSAPRRERSTETAKPQAAANNMSFIGESRDLSKQQPNPSERKRILPAWMLTENSSDQNLSVISGGNNVTWESEKERVCKDKTQVNITQPGKKRLISSGSSESTSAKQDTGKKCKNDDQEESIISSKEMPQSFSAAMLHNTEIDNTKTNPQRSKVPVEALGKVSEHKIITKGSSNEDSTARSCSESYSSTQSKSFCDKPQKSHPEPSSNPPSPECVQAKATDSVPNGSEENKVQRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVNITCQDEADDRPECPYGASCYRKNPQHKIEYRHSTFPVRSISDEDDNVGQPNEYNLNDSFIDDEEEEYEPTDEDSDWEPEKEDLEKEDMEGLLKEAKKFMKRKK | DNA damage response DNA repair-dependent chromatin remodeling double-strand break repair double-strand break repair via nonhomologous end joining embryo implantation regulation of epithelial to mesenchymal transition single strand break repair cytosol; nucleus; site of DNA damage; site of double-strand break 3'-5' exonuclease activity ADP-D-ribose modification-dependent protein binding DNA endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity histone binding histone chaperone activity metal ion binding nucleotide binding poly-ADP-D-ribose binding Bos taurus ADP-ribosylation Chromosome Coiled coil Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Zinc Zinc-finger MSGGFELQPQ MSGGFELQPQDGGPRVALAPGETVIGRGPLLGLHRNPCYYQSSEKSQLLPLKTNIWCWLNPGDHFSLLVDKYIFCVLSTHSEMEMECTLRNSQMLDEDDILNEIPKSSSADLPDKTPSAPRRERSTETAKPQAAANNMSFIGESRDLSKQQPNPSERKRILPAWMLTENSSDQNLSVISGGNNVTWESEKERVCKDKTQVNITQPGKKRLISSGSSESTSAKQDTGKKCKNDDQEESIISSKEMPQSFSAAMLHNTEIDNTKTNPQRSKVPVEALGKVSEHKIITKGSSNEDSTARSCSESYSSTQSKSFCDKPQKSHPEPSSNPPSPECVQAKATDSVPNGSEENKVQRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVNITCQDEADDRPECPYGASCYRKNPQHKIEYRHSTFPVRSISDEDDNVGQPNEYNLNDSFIDDEEEEYEPTDEDSDWEPEKEDLEKEDMEGLLKEAKKFMKRKK |
D-serine biosynthetic process D-serine metabolic process L-serine metabolic process | cytoplasm | ATP binding D-serine ammonia-lyase activity L-serine ammonia-lyase activity magnesium ion binding pyridoxal phosphate binding serine racemase activity threonine racemase activity | Bos taurus | Allosteric enzyme ATP-binding Isomerase Lyase Magnesium Metal-binding Nucleotide-binding Pyridoxal phosphate Reference proteome S-nitrosylation | MCDQYCISFA | MCDQYCISFADVEKAHINIRDFIHLTPVLTSSILNQITGRNLFFKCELFQKTGSFKIRGALNAIRGLISAHPEEKPRAVVAHSSGNHGQALSFAARLEGIPAYVIVPETAPNCKKLAIQAYGASIVYSEQSEESRENITKRIAEETEGIMVHPNQEPAVIAGQGTIAMEVLNQVPLVDALVVPVGGGGMLAGIAVTVKALRPSVKVYAAEPLNADDCYQSKLKGELTPNPYPPETIADGIKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGVAVVLSQHFRTVPAEVKNICIVLSGGNVDLTSLTWVKKQDEKAAP | D-serine biosynthetic process D-serine metabolic process L-serine metabolic process cytoplasm ATP binding D-serine ammonia-lyase activity L-serine ammonia-lyase activity magnesium ion binding pyridoxal phosphate binding serine racemase activity threonine racemase activity Bos taurus Allosteric enzyme ATP-binding Isomerase Lyase Magnesium Metal-binding Nucleotide-binding Pyridoxal phosphate Reference proteome S-nitrosylation MCDQYCISFA MCDQYCISFADVEKAHINIRDFIHLTPVLTSSILNQITGRNLFFKCELFQKTGSFKIRGALNAIRGLISAHPEEKPRAVVAHSSGNHGQALSFAARLEGIPAYVIVPETAPNCKKLAIQAYGASIVYSEQSEESRENITKRIAEETEGIMVHPNQEPAVIAGQGTIAMEVLNQVPLVDALVVPVGGGGMLAGIAVTVKALRPSVKVYAAEPLNADDCYQSKLKGELTPNPYPPETIADGIKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGVAVVLSQHFRTVPAEVKNICIVLSGGNVDLTSLTWVKKQDEKAAP |
bile acid and bile salt transport bile acid secretion positive regulation of protein exit from endoplasmic reticulum positive regulation of protein glycosylation positive regulation of protein targeting to membrane regulation of protein stability | basolateral plasma membrane; membrane; plasma membrane; protein-containing complex | bile acid transmembrane transporter activity protein heterodimerization activity | Bos taurus | Cell membrane Lipid transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MNYSEKLTGA | MNYSEKLTGAPPMTEVPLELLEEMLWFFRVEDATPWNCSMFVLAALVAIISFILLGRNIQANRNQKKLPPEKQTPEVLYLAEGGNKDDKNLTSLTETLLSEKPTLAQGEMEAKCSDVPRVHLPDPQEPES | bile acid and bile salt transport bile acid secretion positive regulation of protein exit from endoplasmic reticulum positive regulation of protein glycosylation positive regulation of protein targeting to membrane regulation of protein stability basolateral plasma membrane; membrane; plasma membrane; protein-containing complex bile acid transmembrane transporter activity protein heterodimerization activity Bos taurus Cell membrane Lipid transport Membrane Reference proteome Transmembrane Transmembrane helix Transport MNYSEKLTGA MNYSEKLTGAPPMTEVPLELLEEMLWFFRVEDATPWNCSMFVLAALVAIISFILLGRNIQANRNQKKLPPEKQTPEVLYLAEGGNKDDKNLTSLTETLLSEKPTLAQGEMEAKCSDVPRVHLPDPQEPES |
Golgi to secretory granule transport neuron projection development vesicle transport along microtubule | centrosome; cytoplasm | dynactin binding small GTPase binding | Mus musculus | 3D-structure Alternative splicing Coiled coil Cytoplasm Cytoskeleton Neurogenesis Reference proteome Transport | MSAFCLGLAG | MSAFCLGLAGRASAPAEPDSACCMELPAGAGDAVRSPATAAALVSFPGGPGELELALEEELALLAAGERSSEPGEHPQAEPESPVEGHGPPLPPPPTQDPELLSVIRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELETDVKQLQDELERQQLHLREADREKTRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALKEDFREKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLELQEVRLSYRQLQGKVEELTEERSLQSSAATSTSLLSEIEQSMEAEELEQEREQLRLQLWEAYCQVRYLCSHLRGNDSADSAVSTDSSMDESSETSSAKDVPAGSLRTALNDLKRLIQSIVDGVEPTVTLLSVEMTALKEERDRLRVTSEDKEPKEQLQKAIRDRDEAIAKKNAVELELAKCKMDMMSLNSQLLDAIQQKLNLSQQLEAWQDDMHRVIDRQLMDTHLKEQSRPAAAAFPRGHGVGRGQEPSTADGKRLFSFFRKI | Golgi to secretory granule transport neuron projection development vesicle transport along microtubule centrosome; cytoplasm dynactin binding small GTPase binding Mus musculus 3D-structure Alternative splicing Coiled coil Cytoplasm Cytoskeleton Neurogenesis Reference proteome Transport MSAFCLGLAG MSAFCLGLAGRASAPAEPDSACCMELPAGAGDAVRSPATAAALVSFPGGPGELELALEEELALLAAGERSSEPGEHPQAEPESPVEGHGPPLPPPPTQDPELLSVIRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELETDVKQLQDELERQQLHLREADREKTRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALKEDFREKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLELQEVRLSYRQLQGKVEELTEERSLQSSAATSTSLLSEIEQSMEAEELEQEREQLRLQLWEAYCQVRYLCSHLRGNDSADSAVSTDSSMDESSETSSAKDVPAGSLRTALNDLKRLIQSIVDGVEPTVTLLSVEMTALKEERDRLRVTSEDKEPKEQLQKAIRDRDEAIAKKNAVELELAKCKMDMMSLNSQLLDAIQQKLNLSQQLEAWQDDMHRVIDRQLMDTHLKEQSRPAAAAFPRGHGVGRGQEPSTADGKRLFSFFRKI |
brain morphogenesis isoprenoid biosynthetic process muscle cell development protein O-linked mannosylation regulation of protein glycosylation | cytosol | cytidylyltransferase activity D-ribitol-5-phosphate cytidylyltransferase activity protein homodimerization activity | Danio rerio | Alternative splicing Cytoplasm Nucleotidyltransferase Reference proteome Transferase | MGTVTIQLSC | MGTVTIQLSCLRHIRKLCFSCPWEGRRLFKMLLQFHHETQRPLDPGCLLPQDAERSADQPGRAVVDFPVAAVLPAGGSGERMGLTTPKQFCSIFNRPLISYTIQAFERLPWIVMVVVVVAKDNHDLMLNIVRKFNHTKVKVVHGGTTRHRSIYNGLQAFSDSTDSSTPKPKVVIIHDAVRPFVEEDLLLKITLAAKEQGASGAIRPLVSTVIATTSESYLDHSLERAKYRASEMPQGFLYDIIFQAYQRCSEFDLEFGTECLHLALQYCGTNARLIEGPPTLWKVTYKRDLAAAEAIIKETLSVSACIIAEAEEEAVELAKTLQKNLNMMETDVIPCGKESNVQYLSKTRNFIHISASASSSLWVLEMVKCFEDIDHARLYPVVIVWVQLSMTKQSADSQETDEFMALASEVKQRNVLLYGIKIDHSKELEQWQRSLERLGQITLVLIRDRNMALTGQMLHV | brain morphogenesis isoprenoid biosynthetic process muscle cell development protein O-linked mannosylation regulation of protein glycosylation cytosol cytidylyltransferase activity D-ribitol-5-phosphate cytidylyltransferase activity protein homodimerization activity Danio rerio Alternative splicing Cytoplasm Nucleotidyltransferase Reference proteome Transferase MGTVTIQLSC MGTVTIQLSCLRHIRKLCFSCPWEGRRLFKMLLQFHHETQRPLDPGCLLPQDAERSADQPGRAVVDFPVAAVLPAGGSGERMGLTTPKQFCSIFNRPLISYTIQAFERLPWIVMVVVVVAKDNHDLMLNIVRKFNHTKVKVVHGGTTRHRSIYNGLQAFSDSTDSSTPKPKVVIIHDAVRPFVEEDLLLKITLAAKEQGASGAIRPLVSTVIATTSESYLDHSLERAKYRASEMPQGFLYDIIFQAYQRCSEFDLEFGTECLHLALQYCGTNARLIEGPPTLWKVTYKRDLAAAEAIIKETLSVSACIIAEAEEEAVELAKTLQKNLNMMETDVIPCGKESNVQYLSKTRNFIHISASASSSLWVLEMVKCFEDIDHARLYPVVIVWVQLSMTKQSADSQETDEFMALASEVKQRNVLLYGIKIDHSKELEQWQRSLERLGQITLVLIRDRNMALTGQMLHV |
negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II regulation of cell growth regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Rattus norvegicus | DNA-binding Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MNCHSVPLQG | MNCHSVPLQGPVSFKDVTVDFTQEEWQRLDPAQKALYRDVMLENYCHFISVGFHITKPDMIRKLEQGEELWTERMFPSQSYLEDEEVLVKFRDYQDKPPTSIVIINHKKLIKERNNVYEKTLGNNHIISKTLFEYKSDGKVLKNISDFISRDINPVMGTLGDSSEWEESVLTSEQEKTHPVPTLYKQIGRNLSSSLELAQHQKTQIPEQRFECDECDSSFLMTEVAFPHDRAHRGVRDFNCSKDEIAFFEKSDLGIHPHNLMEKKCSTYNKYGKLLCRKSVFVMHPRSQVDERPFQCPYCGNSFRRKSYLIEHQRIHTGEKPYICSQCGKAFRQKTALTLHEKTHTDGKPYLCVDCGKSFRQKATLTRHHKTHTGEKAYECTQCGSAFGKKSYLIDHQRTHTGEKPYQCAECGKAFIQKTTLTVHQRTHTGEKPYMCSECGKSFCQKTTLTLHQRIHTGEKPYVCSDCGKSFRQKAILTVHYRIHTGEKSNGCPQCGKAFSRKSNLIRHQKTHTGEKPYECHECGKFFSCKSNLVAHQKTHKAETVRFQ | negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II regulation of cell growth regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding Rattus norvegicus DNA-binding Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger MNCHSVPLQG MNCHSVPLQGPVSFKDVTVDFTQEEWQRLDPAQKALYRDVMLENYCHFISVGFHITKPDMIRKLEQGEELWTERMFPSQSYLEDEEVLVKFRDYQDKPPTSIVIINHKKLIKERNNVYEKTLGNNHIISKTLFEYKSDGKVLKNISDFISRDINPVMGTLGDSSEWEESVLTSEQEKTHPVPTLYKQIGRNLSSSLELAQHQKTQIPEQRFECDECDSSFLMTEVAFPHDRAHRGVRDFNCSKDEIAFFEKSDLGIHPHNLMEKKCSTYNKYGKLLCRKSVFVMHPRSQVDERPFQCPYCGNSFRRKSYLIEHQRIHTGEKPYICSQCGKAFRQKTALTLHEKTHTDGKPYLCVDCGKSFRQKATLTRHHKTHTGEKAYECTQCGSAFGKKSYLIDHQRTHTGEKPYQCAECGKAFIQKTTLTVHQRTHTGEKPYMCSECGKSFCQKTTLTLHQRIHTGEKPYVCSDCGKSFRQKAILTVHYRIHTGEKSNGCPQCGKAFSRKSNLIRHQKTHTGEKPYECHECGKFFSCKSNLVAHQKTHKAETVRFQ |
cellular response to zinc ion starvation intracellular zinc ion homeostasis zinc ion import across plasma membrane zinc ion transmembrane transport | apical plasma membrane; cytoplasmic vesicle; plasma membrane; recycling endosome membrane | identical protein binding metal ion binding monoatomic cation:bicarbonate symporter activity zinc ion binding zinc ion sensor activity zinc ion sequestering activity zinc ion transmembrane transporter activity | Rattus norvegicus | Cell membrane Endosome Glycoprotein Ion transport Membrane Metal-binding Reference proteome Signal Transmembrane Transmembrane helix Transport Ubl conjugation Zinc Zinc transport | MMLPKSLTQG | MMLPKSLTQGLLLAMLVGTAAMVQPYHLLSLLTSGQGALDRTALDGLLNTLVARVHCTDGPCEKCLSVETALALGKPDKPQLAPESVLESRYITYLSAAAALYLNDPEKTCKDIRAGLLASHVDDYLAKLESPEAMTLGLSQLLQKIEAHDASQPTREETCVDVPQLLEEAEEAGVSRSPGLVLTALLDHVLNGSCFQGLPSPQYFVDFVFRQLSSKPRNITLPELEDLMHHLGVGGEDHSDHGDHVDHSHLDREANHQDSELHATHNSSSSVWDTLCLSAKDVMAVYGLSEEAGVSPQAWAQLTPALVQQQLSEACSSSPIIHVQDQLSQAERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHSGEVHSHEEESIGGQSTWRLLAVLGGFYIFFLFESFFNLLLPRDQDHEKDGPCSHGGHSHGISLQLSPSNLRQSKQPHESSRSDLVTEETPELLNPDTRRLRAELRMLPYLITLGDAVHNFADGLAVGAAFSSTWKTGLATSLAVFCHELPHELGDFAALLHAGLTVKRALLLNLASALTAFAGLYVALAVGVGEEGETWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTILLLLSLYEDSITF | cellular response to zinc ion starvation intracellular zinc ion homeostasis zinc ion import across plasma membrane zinc ion transmembrane transport apical plasma membrane; cytoplasmic vesicle; plasma membrane; recycling endosome membrane identical protein binding metal ion binding monoatomic cation:bicarbonate symporter activity zinc ion binding zinc ion sensor activity zinc ion sequestering activity zinc ion transmembrane transporter activity Rattus norvegicus Cell membrane Endosome Glycoprotein Ion transport Membrane Metal-binding Reference proteome Signal Transmembrane Transmembrane helix Transport Ubl conjugation Zinc Zinc transport MMLPKSLTQG MMLPKSLTQGLLLAMLVGTAAMVQPYHLLSLLTSGQGALDRTALDGLLNTLVARVHCTDGPCEKCLSVETALALGKPDKPQLAPESVLESRYITYLSAAAALYLNDPEKTCKDIRAGLLASHVDDYLAKLESPEAMTLGLSQLLQKIEAHDASQPTREETCVDVPQLLEEAEEAGVSRSPGLVLTALLDHVLNGSCFQGLPSPQYFVDFVFRQLSSKPRNITLPELEDLMHHLGVGGEDHSDHGDHVDHSHLDREANHQDSELHATHNSSSSVWDTLCLSAKDVMAVYGLSEEAGVSPQAWAQLTPALVQQQLSEACSSSPIIHVQDQLSQAERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHSGEVHSHEEESIGGQSTWRLLAVLGGFYIFFLFESFFNLLLPRDQDHEKDGPCSHGGHSHGISLQLSPSNLRQSKQPHESSRSDLVTEETPELLNPDTRRLRAELRMLPYLITLGDAVHNFADGLAVGAAFSSTWKTGLATSLAVFCHELPHELGDFAALLHAGLTVKRALLLNLASALTAFAGLYVALAVGVGEEGETWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTILLLLSLYEDSITF |
exocytosis muscle organ development muscle system process negative regulation of insulin receptor signaling pathway negative regulation of insulin-like growth factor receptor signaling pathway negative regulation of myotube differentiation plasma membrane repair proteasome-mediated ubiquitin-dependent protein catabolic process protein homooligomerization protein ubiquitination | cytoplasm; cytoplasmic vesicle membrane; sarcolemma | identical protein binding mitogen-activated protein kinase kinase kinase binding phosphatidylserine binding ubiquitin conjugating enzyme binding ubiquitin protein ligase activity zinc ion binding | Rattus norvegicus | Cell membrane Coiled coil Cytoplasmic vesicle Disulfide bond Exocytosis Membrane Metal-binding Phosphoprotein Reference proteome S-nitrosylation Transport Zinc Zinc-finger | MSTAPGLLRQ | MSTAPGLLRQELSCPLCLQLFDAPVTAECGHSFCRACLIRVAGEPADDGTVACPCCQASTRPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRTLVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKAQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRMFLAALESSLDREAERVRGEAGVALRRELSSLNSYLEQLRQMEKVLEEVADKPQTEFLMKFCLVTSRLQKILSESPPPARLDIQLPVISDDFKFQVWKKMFRALMPELEELTFDPSSAHPSLVVSASGRRVECSEQKAPPAGEDTCQFDKTVAVVAKQLLSQGEHYWEVEVGDKPRWALGVMAADASRRGRLHAVPSQGLWLLGLRDGKILEAHVEAKEPRALRTPERPPARIGLYLSFADGVLTFYDASNTDALTPLFSFHERLPGPVYPMFDVCWHDKGKNSQPLLLVGPDSEQA | exocytosis muscle organ development muscle system process negative regulation of insulin receptor signaling pathway negative regulation of insulin-like growth factor receptor signaling pathway negative regulation of myotube differentiation plasma membrane repair proteasome-mediated ubiquitin-dependent protein catabolic process protein homooligomerization protein ubiquitination cytoplasm; cytoplasmic vesicle membrane; sarcolemma identical protein binding mitogen-activated protein kinase kinase kinase binding phosphatidylserine binding ubiquitin conjugating enzyme binding ubiquitin protein ligase activity zinc ion binding Rattus norvegicus Cell membrane Coiled coil Cytoplasmic vesicle Disulfide bond Exocytosis Membrane Metal-binding Phosphoprotein Reference proteome S-nitrosylation Transport Zinc Zinc-finger MSTAPGLLRQ MSTAPGLLRQELSCPLCLQLFDAPVTAECGHSFCRACLIRVAGEPADDGTVACPCCQASTRPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRTLVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKAQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRMFLAALESSLDREAERVRGEAGVALRRELSSLNSYLEQLRQMEKVLEEVADKPQTEFLMKFCLVTSRLQKILSESPPPARLDIQLPVISDDFKFQVWKKMFRALMPELEELTFDPSSAHPSLVVSASGRRVECSEQKAPPAGEDTCQFDKTVAVVAKQLLSQGEHYWEVEVGDKPRWALGVMAADASRRGRLHAVPSQGLWLLGLRDGKILEAHVEAKEPRALRTPERPPARIGLYLSFADGVLTFYDASNTDALTPLFSFHERLPGPVYPMFDVCWHDKGKNSQPLLLVGPDSEQA |
defense response defense response to bacterium response to bacterium response to cold response to ethylene response to jasmonic acid response to salicylic acid response to salt stress response to water deprivation | apoplast; plasma membrane | LRR domain binding receptor serine/threonine kinase binding | Arabidopsis thaliana | Apoplast Cell membrane Cleavage on pair of basic residues Membrane Reference proteome Secreted Signal | MAAKTSNLVA | MAAKTSNLVALLLSLFLLLLSISSQVGLGEAKRNLRNNLRLDCVSHPSPPPPHRSMAPPIFVPPSTSHKGQGP | defense response defense response to bacterium response to bacterium response to cold response to ethylene response to jasmonic acid response to salicylic acid response to salt stress response to water deprivation apoplast; plasma membrane LRR domain binding receptor serine/threonine kinase binding Arabidopsis thaliana Apoplast Cell membrane Cleavage on pair of basic residues Membrane Reference proteome Secreted Signal MAAKTSNLVA MAAKTSNLVALLLSLFLLLLSISSQVGLGEAKRNLRNNLRLDCVSHPSPPPPHRSMAPPIFVPPSTSHKGQGP |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Aeromonas hydrophila subsp. hydrophila | Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase Reference proteome | MIYQGETLTV | MIYQGETLTVSYLEDGIAELRFDAPGSVNKLDRATLLSLSEAIAALQQERELKGLILTSGKDAFIVGADITEFLELFDLPQADLLGWLKKANDIFSAIEDLPVPTLSAIKGHALGGGCETILSTDFRLADTSAKIGLPETKLGIMPGFGGTVRLPRVIGADNALEWITTGKDYRADDALKVGAIDAVVAPDALQSAAVQMIKDAVKGKLDWQGRRAAKKAPLRLSKLEAMMSFTTAAGMVAAVAGKHYPAPMTAVKTVEAAAGMSRDEALAVEAQGFIKLAKTDVAKALVGIFLNDQHIKALAKKAAKQAAKATSHAAVLGAGIMGGGIAYQSASKGIPAVMKDINEKALALGMGEATKLLNGQLEKGRIDGIKMGQVLSAITPTLSYDNVKHVDVVVEAVVENPKVKAAVLGEVEGIIGEDAVLASNTSTIPISLLAKELKRPQNFCGMHFFNPVHRMPLVEIIRGEQTSDETINRVVAYAAAMGKSPVVVNDCPGFFVNRVLFPYFFGFNKLVADGADFAAVDKVMEKEFGWPMGPAYLLDVVGIDTGHHAGDVMAQGFPARMSKEGRTAIDVMYEVNRFGQKNGKGFYAYEQDKKGKPKKVADAASYELLAPIAKPKQDFDKDAIIARMMIPMINEVVLCLEEGIVATPAEADIALVYGLGFPPFRGGVFRYLDTIGLDRYVAMADQYADLGPLYRVSDKLREMAAQGKTFY | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Aeromonas hydrophila subsp. hydrophila Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase Reference proteome MIYQGETLTV MIYQGETLTVSYLEDGIAELRFDAPGSVNKLDRATLLSLSEAIAALQQERELKGLILTSGKDAFIVGADITEFLELFDLPQADLLGWLKKANDIFSAIEDLPVPTLSAIKGHALGGGCETILSTDFRLADTSAKIGLPETKLGIMPGFGGTVRLPRVIGADNALEWITTGKDYRADDALKVGAIDAVVAPDALQSAAVQMIKDAVKGKLDWQGRRAAKKAPLRLSKLEAMMSFTTAAGMVAAVAGKHYPAPMTAVKTVEAAAGMSRDEALAVEAQGFIKLAKTDVAKALVGIFLNDQHIKALAKKAAKQAAKATSHAAVLGAGIMGGGIAYQSASKGIPAVMKDINEKALALGMGEATKLLNGQLEKGRIDGIKMGQVLSAITPTLSYDNVKHVDVVVEAVVENPKVKAAVLGEVEGIIGEDAVLASNTSTIPISLLAKELKRPQNFCGMHFFNPVHRMPLVEIIRGEQTSDETINRVVAYAAAMGKSPVVVNDCPGFFVNRVLFPYFFGFNKLVADGADFAAVDKVMEKEFGWPMGPAYLLDVVGIDTGHHAGDVMAQGFPARMSKEGRTAIDVMYEVNRFGQKNGKGFYAYEQDKKGKPKKVADAASYELLAPIAKPKQDFDKDAIIARMMIPMINEVVLCLEEGIVATPAEADIALVYGLGFPPFRGGVFRYLDTIGLDRYVAMADQYADLGPLYRVSDKLREMAAQGKTFY |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Shewanella sp. | Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase | MIYQSPTIQV | MIYQSPTIQVELLEDNIAKLCFNAPGSVNKFDRETLASLDAALDSIKQQSNIQALVLTSGKDTFIVGADITEFLGLFAQDDAVLLSWIEQANAVFNKLEDLPFPTASAIKGFALGGGCETILATDFRIADTTAKIGLPETKLGIIPGFGGTVRLPRVIGADNALEWITTGKDQRPEDALKVGAVDAVVAPEALEAAAIQMLKDAVAEKLDWQARRQRKMSPLTLPKLEAMMSFTTAKGMVFAVAGKHYPAPMAAVSVVEQAATKGRSDALQIEHQAFIKLAKTDVAKALIGIFLNDQLVKGKAKKAGKLAKDVKSAAVLGAGIMGGGIAYQSASKGTPIVMKDIAQPALDLGLGEAAKLLSAQVARGRSTPEKMAKVLNNITPALDYAPVKHADVVVEAVVEHPKVKAQVLAEVEQYVSEDAIIASNTSTISINLLAKSMKKPERFCGMHFFNPVHKMPLVEVIRGEHSSEETIASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLAEGGDFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMAEGFPDRMGKSGNDAIDVMFENKRLGQKNGKGFYAYSVDSRGKPKKDVDPTSYELLKAAFGEQKAFDADEIIARTMIPMIIETVRCLEEGIVASPAEADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYAHLGGLYQVTDAMRALAANNGSYYQA | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Shewanella sp. Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase MIYQSPTIQV MIYQSPTIQVELLEDNIAKLCFNAPGSVNKFDRETLASLDAALDSIKQQSNIQALVLTSGKDTFIVGADITEFLGLFAQDDAVLLSWIEQANAVFNKLEDLPFPTASAIKGFALGGGCETILATDFRIADTTAKIGLPETKLGIIPGFGGTVRLPRVIGADNALEWITTGKDQRPEDALKVGAVDAVVAPEALEAAAIQMLKDAVAEKLDWQARRQRKMSPLTLPKLEAMMSFTTAKGMVFAVAGKHYPAPMAAVSVVEQAATKGRSDALQIEHQAFIKLAKTDVAKALIGIFLNDQLVKGKAKKAGKLAKDVKSAAVLGAGIMGGGIAYQSASKGTPIVMKDIAQPALDLGLGEAAKLLSAQVARGRSTPEKMAKVLNNITPALDYAPVKHADVVVEAVVEHPKVKAQVLAEVEQYVSEDAIIASNTSTISINLLAKSMKKPERFCGMHFFNPVHKMPLVEVIRGEHSSEETIASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLAEGGDFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMAEGFPDRMGKSGNDAIDVMFENKRLGQKNGKGFYAYSVDSRGKPKKDVDPTSYELLKAAFGEQKAFDADEIIARTMIPMIIETVRCLEEGIVASPAEADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYAHLGGLYQVTDAMRALAANNGSYYQA |
adaptive immune response B cell receptor signaling pathway immunoglobulin mediated immune response | extracellular region; extracellular space; IgA immunoglobulin complex; IgD immunoglobulin complex; IgE immunoglobulin complex; IgG immunoglobulin complex; IgM immunoglobulin complex; plasma membrane | antigen binding | Homo sapiens | Adaptive immunity Cell membrane Disulfide bond Immunity Immunoglobulin Immunoglobulin domain Membrane Reference proteome Secreted | GQPKAAPSVT | GQPKAAPSVTLFPPSSEELQANKATLVCLVSDFNPGAVTVAWKADGSPVKVGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCRVTHEGSTVEKTVAPAECS | adaptive immune response B cell receptor signaling pathway immunoglobulin mediated immune response extracellular region; extracellular space; IgA immunoglobulin complex; IgD immunoglobulin complex; IgE immunoglobulin complex; IgG immunoglobulin complex; IgM immunoglobulin complex; plasma membrane antigen binding Homo sapiens Adaptive immunity Cell membrane Disulfide bond Immunity Immunoglobulin Immunoglobulin domain Membrane Reference proteome Secreted GQPKAAPSVT GQPKAAPSVTLFPPSSEELQANKATLVCLVSDFNPGAVTVAWKADGSPVKVGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCRVTHEGSTVEKTVAPAECS |
caveola assembly cell differentiation endoplasmic reticulum organization insulin receptor signaling pathway mitochondrion organization negative regulation of endothelial cell proliferation positive regulation of dopamine receptor signaling pathway positive regulation of MAPK cascade regulation of cytosolic calcium ion concentration skeletal muscle fiber development vesicle docking vesicle fusion | caveola; cytoplasmic vesicle; Golgi apparatus; Golgi membrane; nucleus; perinuclear region of cytoplasm; plasma membrane raft | D1 dopamine receptor binding molecular adaptor activity protein kinase binding | Felis catus | Cell membrane Cytoplasm Golgi apparatus Membrane Nucleus Phosphoprotein Reference proteome | MGLETEKADV | MGLETEKADVQLFMDDDSYSRHSGVDYADPDKFADSGSDRDPHRLNSNLKVGFEDVIAEPVSTHSFDKVWICSHALFEISKYVIYKFLTLFLAIPLAFAAGILFATLSCLHIWIIMPFVKTCLMVLPSVQTIWKSITDVVIAPLCTSVGRSFSSVSLQLSHD | caveola assembly cell differentiation endoplasmic reticulum organization insulin receptor signaling pathway mitochondrion organization negative regulation of endothelial cell proliferation positive regulation of dopamine receptor signaling pathway positive regulation of MAPK cascade regulation of cytosolic calcium ion concentration skeletal muscle fiber development vesicle docking vesicle fusion caveola; cytoplasmic vesicle; Golgi apparatus; Golgi membrane; nucleus; perinuclear region of cytoplasm; plasma membrane raft D1 dopamine receptor binding molecular adaptor activity protein kinase binding Felis catus Cell membrane Cytoplasm Golgi apparatus Membrane Nucleus Phosphoprotein Reference proteome MGLETEKADV MGLETEKADVQLFMDDDSYSRHSGVDYADPDKFADSGSDRDPHRLNSNLKVGFEDVIAEPVSTHSFDKVWICSHALFEISKYVIYKFLTLFLAIPLAFAAGILFATLSCLHIWIIMPFVKTCLMVLPSVQTIWKSITDVVIAPLCTSVGRSFSSVSLQLSHD |
atrial cardiac muscle tissue morphogenesis canonical Wnt signaling pathway cardiac epithelial to mesenchymal transition cardiac muscle cell proliferation cell fate commitment cell proliferation in midbrain cellular response to transforming growth factor beta stimulus epithelial cell proliferation involved in lung morphogenesis labyrinthine layer blood vessel development lung induction mammary gland epithelium development mesenchymal cell proliferation midbrain dopaminergic neuron differentiation neuron differentiation positive regulation of cardiac muscle cell proliferation positive regulation of epithelial cell proliferation involved in lung morphogenesis positive regulation of fibroblast proliferation positive regulation of mesenchymal cell proliferation positive regulation of neurogenesis positive regulation of transcription by RNA polymerase II | collagen-containing extracellular matrix; cytoplasm; extracellular space | cytokine activity frizzled binding | Felis catus | Developmental protein Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Secreted Signal Wnt signaling pathway | MNAPLGGIWP | MNAPLGGIWPWLPLLLTWLTPEVSSSWWYMRATGGSSRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAVSSAGVVFAITRACSQGELKSCSCDPKKKGTAKDSKGNFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCECKFHWCCAVRCQDCLEALDVHTCKAPKSVDWAAPT | atrial cardiac muscle tissue morphogenesis canonical Wnt signaling pathway cardiac epithelial to mesenchymal transition cardiac muscle cell proliferation cell fate commitment cell proliferation in midbrain cellular response to transforming growth factor beta stimulus epithelial cell proliferation involved in lung morphogenesis labyrinthine layer blood vessel development lung induction mammary gland epithelium development mesenchymal cell proliferation midbrain dopaminergic neuron differentiation neuron differentiation positive regulation of cardiac muscle cell proliferation positive regulation of epithelial cell proliferation involved in lung morphogenesis positive regulation of fibroblast proliferation positive regulation of mesenchymal cell proliferation positive regulation of neurogenesis positive regulation of transcription by RNA polymerase II collagen-containing extracellular matrix; cytoplasm; extracellular space cytokine activity frizzled binding Felis catus Developmental protein Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Secreted Signal Wnt signaling pathway MNAPLGGIWP MNAPLGGIWPWLPLLLTWLTPEVSSSWWYMRATGGSSRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAVSSAGVVFAITRACSQGELKSCSCDPKKKGTAKDSKGNFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCECKFHWCCAVRCQDCLEALDVHTCKAPKSVDWAAPT |
abscisic acid-activated signaling pathway defense response ethylene-activated signaling pathway lateral root development mitochondria-nucleus signaling pathway positive regulation of DNA-templated transcription regulation of L-ascorbic acid biosynthetic process regulation of protein localization regulation of stomatal movement regulation of triglyceride catabolic process response to glucose response to osmotic stress response to sucrose response to trehalose response to water deprivation root meristem growth seed development starch catabolic process sugar mediated signaling pathway | nucleus | DNA binding DNA-binding transcription factor activity sequence-specific DNA binding transcription cis-regulatory region binding | Arabidopsis thaliana | Abscisic acid signaling pathway DNA-binding Ethylene signaling pathway Nucleus Plant defense Reference proteome Repressor Stress response Transcription Transcription regulation | MDPLASQHQH | MDPLASQHQHNHLEDNNQTLTHNNPQSDSTTDSSTSSAQRKRKGKGGPDNSKFRYRGVRQRSWGKWVAEIREPRKRTRKWLGTFATAEDAARAYDRAAVYLYGSRAQLNLTPSSPSSVSSSSSSVSAASSPSTSSSSTQTLRPLLPRPAAATVGGGANFGPYGIPFNNNIFLNGGTSMLCPSYGFFPQQQQQQNQMVQMGQFQHQQYQNLHSNTNNNKISDIELTDVPVTNSTSFHHEVALGQEQGGSGCNNNSSMEDLNSLAGSVGSSLSITHPPPLVDPVCSMGLDPGYMVGDGSSTIWPFGGEEEYSHNWGSIWDFIDPILGEFY | abscisic acid-activated signaling pathway defense response ethylene-activated signaling pathway lateral root development mitochondria-nucleus signaling pathway positive regulation of DNA-templated transcription regulation of L-ascorbic acid biosynthetic process regulation of protein localization regulation of stomatal movement regulation of triglyceride catabolic process response to glucose response to osmotic stress response to sucrose response to trehalose response to water deprivation root meristem growth seed development starch catabolic process sugar mediated signaling pathway nucleus DNA binding DNA-binding transcription factor activity sequence-specific DNA binding transcription cis-regulatory region binding Arabidopsis thaliana Abscisic acid signaling pathway DNA-binding Ethylene signaling pathway Nucleus Plant defense Reference proteome Repressor Stress response Transcription Transcription regulation MDPLASQHQH MDPLASQHQHNHLEDNNQTLTHNNPQSDSTTDSSTSSAQRKRKGKGGPDNSKFRYRGVRQRSWGKWVAEIREPRKRTRKWLGTFATAEDAARAYDRAAVYLYGSRAQLNLTPSSPSSVSSSSSSVSAASSPSTSSSSTQTLRPLLPRPAAATVGGGANFGPYGIPFNNNIFLNGGTSMLCPSYGFFPQQQQQQNQMVQMGQFQHQQYQNLHSNTNNNKISDIELTDVPVTNSTSFHHEVALGQEQGGSGCNNNSSMEDLNSLAGSVGSSLSITHPPPLVDPVCSMGLDPGYMVGDGSSTIWPFGGEEEYSHNWGSIWDFIDPILGEFY |
heparan sulfate proteoglycan biosynthetic process, enzymatic modification | membrane | 3'-phosphoadenosine 5'-phosphosulfate binding heparan sulfate 6-O-sulfotransferase activity oligosaccharide binding sulfotransferase activity | Danio rerio | 3D-structure Glycoprotein Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MNDKPNKWIF | MNDKPNKWIFIPILAILFVMIGYQYVCPAGGQACHFRTGDKLVRIAPLATPDPTTDDLYREQDPEEDNPPKCASKFNFTERDLTRDVDFNIKGDDVIVFLHIQKTGGTTFGRHLVRNIRLEQPCDCKAGQKKCTCHRPGKQESWLFSRFSTGWSCGLHADWTELTNCVPVIMDKRQPPKRKRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTQDELPTCYNGDDWSGVTLHDFMDCPSNLANNRQVRMLADLSLVGCYNLSTMNESERNPILLASAKSNLKNMAFYGLTEFQRKTQYLFERTFHLRFISAFTQINSTRAANVELRDDMRSRIEQLNMLDMQLYEFAKDLFLQRYQFVRQRERQEERLKRREERRWIRERRVNQSKEPIVENQTRVTTTEDYASQVVRW | heparan sulfate proteoglycan biosynthetic process, enzymatic modification membrane 3'-phosphoadenosine 5'-phosphosulfate binding heparan sulfate 6-O-sulfotransferase activity oligosaccharide binding sulfotransferase activity Danio rerio 3D-structure Glycoprotein Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix MNDKPNKWIF MNDKPNKWIFIPILAILFVMIGYQYVCPAGGQACHFRTGDKLVRIAPLATPDPTTDDLYREQDPEEDNPPKCASKFNFTERDLTRDVDFNIKGDDVIVFLHIQKTGGTTFGRHLVRNIRLEQPCDCKAGQKKCTCHRPGKQESWLFSRFSTGWSCGLHADWTELTNCVPVIMDKRQPPKRKRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTQDELPTCYNGDDWSGVTLHDFMDCPSNLANNRQVRMLADLSLVGCYNLSTMNESERNPILLASAKSNLKNMAFYGLTEFQRKTQYLFERTFHLRFISAFTQINSTRAANVELRDDMRSRIEQLNMLDMQLYEFAKDLFLQRYQFVRQRERQEERLKRREERRWIRERRVNQSKEPIVENQTRVTTTEDYASQVVRW |
actin polymerization or depolymerization decidualization dendrite development negative regulation of apoptotic process negative regulation of endothelial cell proliferation negative regulation of inflammatory response negative regulation of insulin secretion negative regulation of interleukin-1 beta production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of cytosolic calcium ion concentration positive regulation of insulin secretion positive regulation of MAPK cascade positive regulation of response to food positive regulation of synapse assembly regulation of cell population proliferation regulation of response to food response to estrogen response to hormone | axon; extracellular region; extracellular space | ghrelin receptor binding growth hormone-releasing hormone activity hormone activity protein tyrosine kinase activator activity | Papio hamadryas | Amidation Hormone Lipoprotein Secreted Signal | MPSPGTVCSL | MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRAQQRKESKKPPAKLQPRALGGWLRPEDGDQAEGAEDELEIQFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK | actin polymerization or depolymerization decidualization dendrite development negative regulation of apoptotic process negative regulation of endothelial cell proliferation negative regulation of inflammatory response negative regulation of insulin secretion negative regulation of interleukin-1 beta production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of cytosolic calcium ion concentration positive regulation of insulin secretion positive regulation of MAPK cascade positive regulation of response to food positive regulation of synapse assembly regulation of cell population proliferation regulation of response to food response to estrogen response to hormone axon; extracellular region; extracellular space ghrelin receptor binding growth hormone-releasing hormone activity hormone activity protein tyrosine kinase activator activity Papio hamadryas Amidation Hormone Lipoprotein Secreted Signal MPSPGTVCSL MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRAQQRKESKKPPAKLQPRALGGWLRPEDGDQAEGAEDELEIQFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK |
circadian regulation of gene expression circadian rhythm negative regulation of DNA-templated transcription negative regulation of fat cell differentiation negative regulation of glucocorticoid receptor signaling pathway negative regulation of TOR signaling oxidative stress-induced premature senescence positive regulation of canonical Wnt signaling pathway positive regulation of circadian rhythm positive regulation of DNA-templated transcription positive regulation of protein acetylation positive regulation of skeletal muscle cell differentiation positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process regulation of cell cycle regulation of cellular senescence regulation of DNA-templated transcription regulation of hair cycle regulation of insulin secretion regulation of neurogenesis regulation of transcription by RNA polymerase II regulation of type B pancreatic cell development response to redox state spermatogenesis | aryl hydrocarbon receptor complex; chromatoid body; CLOCK-BMAL transcription complex; nucleus; PML body; transcription regulator complex | aryl hydrocarbon receptor binding DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding Hsp90 protein binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription cis-regulatory region binding | Equus caballus | Acetylation Activator Biological rhythms Cytoplasm DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation | MADQRMDISS | MADQRMDISSTISDFMSPGATDLLSSPLGTSGMDCNRKRKGSSTDYQESMDTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEVMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLPPGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL | circadian regulation of gene expression circadian rhythm negative regulation of DNA-templated transcription negative regulation of fat cell differentiation negative regulation of glucocorticoid receptor signaling pathway negative regulation of TOR signaling oxidative stress-induced premature senescence positive regulation of canonical Wnt signaling pathway positive regulation of circadian rhythm positive regulation of DNA-templated transcription positive regulation of protein acetylation positive regulation of skeletal muscle cell differentiation positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process regulation of cell cycle regulation of cellular senescence regulation of DNA-templated transcription regulation of hair cycle regulation of insulin secretion regulation of neurogenesis regulation of transcription by RNA polymerase II regulation of type B pancreatic cell development response to redox state spermatogenesis aryl hydrocarbon receptor complex; chromatoid body; CLOCK-BMAL transcription complex; nucleus; PML body; transcription regulator complex aryl hydrocarbon receptor binding DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding Hsp90 protein binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription cis-regulatory region binding Equus caballus Acetylation Activator Biological rhythms Cytoplasm DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation MADQRMDISS MADQRMDISSTISDFMSPGATDLLSSPLGTSGMDCNRKRKGSSTDYQESMDTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEVMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLPPGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL |
proteolysis | Golgi membrane | aspartic-type endopeptidase activity | Toxoplasma gondii | Aspartyl protease Golgi apparatus Hydrolase Membrane Protease Signal Transmembrane Transmembrane helix | MEAGAMGGSS | MEAGAMGGSSFLSFSSGPSAETSPSSLSPPTSSSPSPSPQLVSDSVESLHAKRPLAQSSRSSSRTAASTCFCWQGEGQENEAAPTISQEERRGGSMTAASAGHLETAREEAARCLGCSYTGEERRGASSATSVLSLGGERGRPPSRSSSLWTFSGLLSPLAFRSRRCCPQFSSSSSPLSPLPHPRGAPASACGSAVITDRAGRPASPLSFSRLASPVSDPSGVCPPRVVAARVWRLLSSVLFSLVNCARLFPRRLSRRPDPLRKPRAQVWSASSRSLQALLLATVALFAACSSLHGSSLLGAQAASPTPPFLSLSSSPRSLASDSAKKGSNAPEQSREQRGEREGERQRPDKGEENGETEETFPAASGVVPAPGLKVADLPRTGPPVDLLGLPIRKKVFRARLYGSMFSYAYYFLDILVGTPPQRASVILDTGSSLLAFPCAGCSECGQHLDPAMDTSRSATGEWIDCKEQERCFGSCSGGTPLGGLGGGGVSSMRRCMYTQTYSEGSAIRGIYFSDVVALGEVEQKNPPVRYDFVGCHTQETNLFVTQKAAGIFGISFPKGHRQPTLLDVMFGHTNLVDKKMFSVCISEDGGLLTVGGYEPTLLVAPPESESTPATEALRPVAGESASRRISEKTSPHHAALLTWTSIISHSTYRVPLSGMEVEGLVLGSGVDDFGNTMVDSGTDLSSIFPPIKVSFGDEKNSQVWWWPEGYLYRRTGGYFCDGLDDNKVSASVLGLSFFKNKQVLFDREQDRVGFAAAKCPSFFLDQRPRGPDSGDGPKGRPTAPFTVPPLRVPVPMDGGGVPGDAKQPEGLPLSPQQLWVAAALVVVAILIAVTVILLHTIKRPSRSSAVVPAPSAPRLPFAQNSKSAGRFARGLGHGALGVGNPVYVQRTQRYREVQEAQPHTADAYYDVEEDRFTGEDDGDFFGDDSVPSAEEQETAPSLSLREESSPFSASQSTLLDLPLGGE | proteolysis Golgi membrane aspartic-type endopeptidase activity Toxoplasma gondiiAspartyl protease Golgi apparatus Hydrolase Membrane Protease Signal Transmembrane Transmembrane helix MEAGAMGGSS MEAGAMGGSSFLSFSSGPSAETSPSSLSPPTSSSPSPSPQLVSDSVESLHAKRPLAQSSRSSSRTAASTCFCWQGEGQENEAAPTISQEERRGGSMTAASAGHLETAREEAARCLGCSYTGEERRGASSATSVLSLGGERGRPPSRSSSLWTFSGLLSPLAFRSRRCCPQFSSSSSPLSPLPHPRGAPASACGSAVITDRAGRPASPLSFSRLASPVSDPSGVCPPRVVAARVWRLLSSVLFSLVNCARLFPRRLSRRPDPLRKPRAQVWSASSRSLQALLLATVALFAACSSLHGSSLLGAQAASPTPPFLSLSSSPRSLASDSAKKGSNAPEQSREQRGEREGERQRPDKGEENGETEETFPAASGVVPAPGLKVADLPRTGPPVDLLGLPIRKKVFRARLYGSMFSYAYYFLDILVGTPPQRASVILDTGSSLLAFPCAGCSECGQHLDPAMDTSRSATGEWIDCKEQERCFGSCSGGTPLGGLGGGGVSSMRRCMYTQTYSEGSAIRGIYFSDVVALGEVEQKNPPVRYDFVGCHTQETNLFVTQKAAGIFGISFPKGHRQPTLLDVMFGHTNLVDKKMFSVCISEDGGLLTVGGYEPTLLVAPPESESTPATEALRPVAGESASRRISEKTSPHHAALLTWTSIISHSTYRVPLSGMEVEGLVLGSGVDDFGNTMVDSGTDLSSIFPPIKVSFGDEKNSQVWWWPEGYLYRRTGGYFCDGLDDNKVSASVLGLSFFKNKQVLFDREQDRVGFAAAKCPSFFLDQRPRGPDSGDGPKGRPTAPFTVPPLRVPVPMDGGGVPGDAKQPEGLPLSPQQLWVAAALVVVAILIAVTVILLHTIKRPSRSSAVVPAPSAPRLPFAQNSKSAGRFARGLGHGALGVGNPVYVQRTQRYREVQEAQPHTADAYYDVEEDRFTGEDDGDFFGDDSVPSAEEQETAPSLSLREESSPFSASQSTLLDLPLGGE |
base-excision repair DNA demethylation heart contraction heart looping negative regulation of apoptotic process positive regulation of gene expression | endoplasmic reticulum; mitochondrion; nuclear speck; nucleolus; nucleus | class II DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(abasic site) binding DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA 3'-5' DNA exonuclease activity metal ion binding phosphoric diester hydrolase activity RNA binding | Danio rerio | 3D-structure Cytoplasm DNA damage DNA repair DNA-binding Endonuclease Endoplasmic reticulum Hydrolase Magnesium Metal-binding Mitochondrion Nuclease Nucleus Reference proteome RNA-binding | MPKRAKKNEE | MPKRAKKNEEGVDGEADNGTAAAKKEKKGKEPEAPILYEDPPEKLTSKDGRAANMKITSWNVDGLRAWVKKNGLDWVRKEDPDILCLQETKCAEKALPADITGMPEYPHKYWAGSEDKEGYSGVAMLCKTEPLNVTYGIGKEEHDKEGRVITAEFPDFFLVTAYVPNASRGLVRLDYRKTWDVDFRAYLCGLDARKPLVLCGDLNVAHQEIDLKNPKGNRKNAGFTPEEREGFTQLLEAGFTDSFRELYPDQAYAYTFWTYMMNARSKNVGWRLDYFVLSSALLPGLCDSKIRNTAMGSDHCPITLFLAV | base-excision repair DNA demethylation heart contraction heart looping negative regulation of apoptotic process positive regulation of gene expression endoplasmic reticulum; mitochondrion; nuclear speck; nucleolus; nucleus class II DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(abasic site) binding DNA-(apurinic or apyrimidinic site) endonuclease activity double-stranded DNA 3'-5' DNA exonuclease activity metal ion binding phosphoric diester hydrolase activity RNA binding Danio rerio 3D-structure Cytoplasm DNA damage DNA repair DNA-binding Endonuclease Endoplasmic reticulum Hydrolase Magnesium Metal-binding Mitochondrion Nuclease Nucleus Reference proteome RNA-binding MPKRAKKNEE MPKRAKKNEEGVDGEADNGTAAAKKEKKGKEPEAPILYEDPPEKLTSKDGRAANMKITSWNVDGLRAWVKKNGLDWVRKEDPDILCLQETKCAEKALPADITGMPEYPHKYWAGSEDKEGYSGVAMLCKTEPLNVTYGIGKEEHDKEGRVITAEFPDFFLVTAYVPNASRGLVRLDYRKTWDVDFRAYLCGLDARKPLVLCGDLNVAHQEIDLKNPKGNRKNAGFTPEEREGFTQLLEAGFTDSFRELYPDQAYAYTFWTYMMNARSKNVGWRLDYFVLSSALLPGLCDSKIRNTAMGSDHCPITLFLAV |
proteolysis | periplasmic space | aminopeptidase activity | Sphingosinicella microcystinivorans | Aminopeptidase Hydrolase Periplasm Protease Signal | MHYLKFPAII | MHYLKFPAIIAGMLLAGAASAEGPRARDLGVPFAGKPGANNAITDVAGVEVGYVSLISGEGKLERGKGPVRTGVTAVLPRGKESRTPVYAGWETSNAAGEMTGTVWLEERGYFDGPMMITNTHSVGVVRDAVVGWLADVKWPGAWFTPVVAETYDGMLNDINGFHVKPEHALRAIQTAASGPVAEGNVGGGVGMQCFGFKGGTGTASRVVEMDGKSYTVGVLVQCNFGMRPWLRVAGAPVGEELAGKYLPETRGTQTAAATNNGVAPGDGSIIVVMATDAPMLPHQLKRLAKRAAAGMGRMGDAGSNGSGDIFVAFSTANANVQSVGGNVISVETMPNDKLTLIFEAATQATEEAITNVLVAADTLTGVNGYTIQRLPHAELRAILKKYRRLAAAK | proteolysis periplasmic space aminopeptidase activity Sphingosinicella microcystinivoransAminopeptidase Hydrolase Periplasm Protease Signal MHYLKFPAII MHYLKFPAIIAGMLLAGAASAEGPRARDLGVPFAGKPGANNAITDVAGVEVGYVSLISGEGKLERGKGPVRTGVTAVLPRGKESRTPVYAGWETSNAAGEMTGTVWLEERGYFDGPMMITNTHSVGVVRDAVVGWLADVKWPGAWFTPVVAETYDGMLNDINGFHVKPEHALRAIQTAASGPVAEGNVGGGVGMQCFGFKGGTGTASRVVEMDGKSYTVGVLVQCNFGMRPWLRVAGAPVGEELAGKYLPETRGTQTAAATNNGVAPGDGSIIVVMATDAPMLPHQLKRLAKRAAAGMGRMGDAGSNGSGDIFVAFSTANANVQSVGGNVISVETMPNDKLTLIFEAATQATEEAITNVLVAADTLTGVNGYTIQRLPHAELRAILKKYRRLAAAK |
actin filament bundle retrograde transport axonogenesis Cdc42 protein signal transduction cytoplasmic actin-based contraction involved in cell motility endoplasmic reticulum polarization netrin-activated signaling pathway neuron projection morphogenesis positive regulation of axon extension positive regulation of neuron migration Ras protein signal transduction regulation of establishment of cell polarity substrate-dependent cell migration, cell extension | axon; axonal growth cone; cell leading edge; cytoplasm; filopodium; growth cone; lamellipodium; microtubule; microtubule associated complex; microtubule cytoskeleton; perikaryon; perinuclear region of cytoplasm | actin filament binding cadherin binding identical protein binding kinesin binding | Homo sapiens | Acetylation Alternative splicing Cell projection Coiled coil Cytoplasm Cytoskeleton Developmental protein Direct protein sequencing Phosphoprotein Reference proteome | MNSSDEEKQL | MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERILRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEPGEGPRKLEGCTSSKVTFQPPSSIGCRKKYIDGEKQAEPVVVLDPVSTHEPQTKDQVAEKDPTQHKEDEGEIQPENKEDSIENVRETDSSNC | actin filament bundle retrograde transport axonogenesis Cdc42 protein signal transduction cytoplasmic actin-based contraction involved in cell motility endoplasmic reticulum polarization netrin-activated signaling pathway neuron projection morphogenesis positive regulation of axon extension positive regulation of neuron migration Ras protein signal transduction regulation of establishment of cell polarity substrate-dependent cell migration, cell extension axon; axonal growth cone; cell leading edge; cytoplasm; filopodium; growth cone; lamellipodium; microtubule; microtubule associated complex; microtubule cytoskeleton; perikaryon; perinuclear region of cytoplasm actin filament binding cadherin binding identical protein binding kinesin binding Homo sapiens Acetylation Alternative splicing Cell projection Coiled coil Cytoplasm Cytoskeleton Developmental protein Direct protein sequencing Phosphoprotein Reference proteome MNSSDEEKQL MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELERILRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEPGEGPRKLEGCTSSKVTFQPPSSIGCRKKYIDGEKQAEPVVVLDPVSTHEPQTKDQVAEKDPTQHKEDEGEIQPENKEDSIENVRETDSSNC |
actin filament bundle retrograde transport axonogenesis Cdc42 protein signal transduction cytoplasmic actin-based contraction involved in cell motility endoplasmic reticulum polarization netrin-activated signaling pathway neuron projection morphogenesis positive regulation of axon extension positive regulation of neuron migration Ras protein signal transduction regulation of establishment of cell polarity regulation of neuron migration substrate-dependent cell migration, cell extension | axon; axonal growth cone; cell leading edge; cytoplasm; cytosol; filopodium; growth cone; lamellipodium; microtubule associated complex; microtubule cytoskeleton; perikaryon; perinuclear region of cytoplasm | actin filament binding cell adhesion molecule binding kinesin binding | Rattus norvegicus | Acetylation Alternative splicing Cell projection Coiled coil Cytoplasm Cytoskeleton Developmental protein Phosphoprotein Reference proteome | MNSSDEEKQL | MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKETCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDDDPGTDTDAAAETCVSVQCQKQIKELRDQIVSVQEEKKVLAIELESLKSKLGEVMEEVNKVKQEKAVLNSEVLEQRKVLEKCNRVSVLAVEEYEELQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSLPDQQLLKALDENAKLIQQLEEERIQHQQKVKELEERLENEALHKEIHNLRQQLELLEDDKRELEQKYQSSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGGSTKKEKATQPETAEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKAKPDSLKGSESAVDELKGILGTLNKSTSSRSLKSLGPENSETELERILRRRKLTAEADSSSPTGILATSESKSMPVLGSVSSVTKSALNKKTLEAEFNNPCPLTPEPGEGPRKLEGCTNSKVTFQPPSKGGYRRKCVGSENQSEPVVVLDPVSTHEPQTKDQAAEKDPTQCKEEERGETQPEFKEDSSGGKTGETDSSNC | actin filament bundle retrograde transport axonogenesis Cdc42 protein signal transduction cytoplasmic actin-based contraction involved in cell motility endoplasmic reticulum polarization netrin-activated signaling pathway neuron projection morphogenesis positive regulation of axon extension positive regulation of neuron migration Ras protein signal transduction regulation of establishment of cell polarity regulation of neuron migration substrate-dependent cell migration, cell extension axon; axonal growth cone; cell leading edge; cytoplasm; cytosol; filopodium; growth cone; lamellipodium; microtubule associated complex; microtubule cytoskeleton; perikaryon; perinuclear region of cytoplasm actin filament binding cell adhesion molecule binding kinesin binding Rattus norvegicus Acetylation Alternative splicing Cell projection Coiled coil Cytoplasm Cytoskeleton Developmental protein Phosphoprotein Reference proteome MNSSDEEKQL MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKETCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDDDPGTDTDAAAETCVSVQCQKQIKELRDQIVSVQEEKKVLAIELESLKSKLGEVMEEVNKVKQEKAVLNSEVLEQRKVLEKCNRVSVLAVEEYEELQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSLPDQQLLKALDENAKLIQQLEEERIQHQQKVKELEERLENEALHKEIHNLRQQLELLEDDKRELEQKYQSSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGGSTKKEKATQPETAEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKAKPDSLKGSESAVDELKGILGTLNKSTSSRSLKSLGPENSETELERILRRRKLTAEADSSSPTGILATSESKSMPVLGSVSSVTKSALNKKTLEAEFNNPCPLTPEPGEGPRKLEGCTNSKVTFQPPSKGGYRRKCVGSENQSEPVVVLDPVSTHEPQTKDQAAEKDPTQCKEEERGETQPEFKEDSSGGKTGETDSSNC |
fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell | host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Bear Canyon mammarenavirus | Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell Zinc | MGQLVSFIGE | MGQLVSFIGEIPAIVHEALNVALIAVSIIAIMKGLINIWKSGLFQLIMFLILAGRSCSISIGHHLELQHFIINSTSLLPSMPTLCRINATNSLIRGPFSAQWGLDIFIGDLTILVNPEPGSKTKRMTATNITGCFPNNEDPDSVAQVLSWFFRGVHHDFHLDPTILCDESVTVFRIQMNLTERMYCDRIVSKLARLFGSFGDYCSKVGKKLVIIRNVTWSNQCHEDHVGSMQLILQNAHNQVMRFRKLQNFFSWSLVDSAGNSMPGGYCLEKWMLVASELKCFGNTAVAKCNINHDSEFCDMLRLFDYNKKAIVNLQDKTKAQLDSLIDAVNSLISDNLITKNKIRELMNIPYCNYTKFWYVNHTGLNVHSLPKCWHVRNGSYLNESDFRNEWIIESDHLVSEILAKEYEERQKRTPLSLVDLCFWSTLFYTASIFLHLLHIPTHRHIIGEGCPKPHRLTSDSLCACGFFQLKGRPTRWARIP | fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Bear Canyon mammarenavirus Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell Zinc MGQLVSFIGE MGQLVSFIGEIPAIVHEALNVALIAVSIIAIMKGLINIWKSGLFQLIMFLILAGRSCSISIGHHLELQHFIINSTSLLPSMPTLCRINATNSLIRGPFSAQWGLDIFIGDLTILVNPEPGSKTKRMTATNITGCFPNNEDPDSVAQVLSWFFRGVHHDFHLDPTILCDESVTVFRIQMNLTERMYCDRIVSKLARLFGSFGDYCSKVGKKLVIIRNVTWSNQCHEDHVGSMQLILQNAHNQVMRFRKLQNFFSWSLVDSAGNSMPGGYCLEKWMLVASELKCFGNTAVAKCNINHDSEFCDMLRLFDYNKKAIVNLQDKTKAQLDSLIDAVNSLISDNLITKNKIRELMNIPYCNYTKFWYVNHTGLNVHSLPKCWHVRNGSYLNESDFRNEWIIESDHLVSEILAKEYEERQKRTPLSLVDLCFWSTLFYTASIFLHLLHIPTHRHIIGEGCPKPHRLTSDSLCACGFFQLKGRPTRWARIP |
hexose transmembrane transport | apical plasma membrane; extracellular exosome; plasma membrane | fructose:sodium symporter activity glucose:sodium symporter activity mannose:sodium symporter activity solute:sodium symporter activity | Homo sapiens | Alternative splicing Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Sodium Sodium transport Sugar transport Transmembrane Transmembrane helix Transport | MAANSTSDLH | MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILLMCVNIFFYAYFA | hexose transmembrane transport apical plasma membrane; extracellular exosome; plasma membrane fructose:sodium symporter activity glucose:sodium symporter activity mannose:sodium symporter activity solute:sodium symporter activity Homo sapiens Alternative splicing Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Reference proteome Sodium Sodium transport Sugar transport Transmembrane Transmembrane helix Transport MAANSTSDLH MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILLMCVNIFFYAYFA |
axon guidance cell dedifferentiation forebrain anterior/posterior pattern specification interneuron migration negative regulation of cell population proliferation olfactory bulb development positive regulation of DNA-templated transcription positive regulation of neuron differentiation regulation of neurogenesis regulation of transcription by RNA polymerase II | cytosol; nucleoplasm | DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Homo sapiens | Alternative splicing Developmental protein Differentiation Disease variant DNA-binding Hypogonadotropic hypogonadism Kallmann syndrome Metal-binding Neurogenesis Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MDSSCHNATT | MDSSCHNATTKMLATAPARGNMMSTSKPLAFSIERIMARTPEPKALPVPHFLQGALPKGEPKHSLHLNSSIPCMIPFVPVAYDTSPKAGVTGSEPRKASLEAPAAPAAVPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAAGVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKYPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLARTPAGEPGTEPPPPLPQQPPMTLPPLQPPLPTPGPLQPGLHQGHQ | axon guidance cell dedifferentiation forebrain anterior/posterior pattern specification interneuron migration negative regulation of cell population proliferation olfactory bulb development positive regulation of DNA-templated transcription positive regulation of neuron differentiation regulation of neurogenesis regulation of transcription by RNA polymerase II cytosol; nucleoplasm DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding Homo sapiens Alternative splicing Developmental protein Differentiation Disease variant DNA-binding Hypogonadotropic hypogonadism Kallmann syndrome Metal-binding Neurogenesis Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger MDSSCHNATT MDSSCHNATTKMLATAPARGNMMSTSKPLAFSIERIMARTPEPKALPVPHFLQGALPKGEPKHSLHLNSSIPCMIPFVPVAYDTSPKAGVTGSEPRKASLEAPAAPAAVPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAAGVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKYPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLARTPAGEPGTEPPPPLPQQPPMTLPPLQPPLPTPGPLQPGLHQGHQ |
DNA topological change DNA-templated DNA replication | chromosome; cytoplasm | ATP binding DNA binding DNA negative supercoiling activity metal ion binding | Mycolicibacterium smegmatis 155) | 3D-structure ATP-binding Cytoplasm Direct protein sequencing DNA-binding Isomerase Magnesium Metal-binding Nucleotide-binding Reference proteome Topoisomerase | MAAQKNNAPK | MAAQKNNAPKEYGADSITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGFATRVDVKIHADGSVEVRDDGRGIPVEMHATGMPTIDVVMTQLHAGGKFDGETYAVSGGLHGVGVSVVNALSTRLEATVLRDGYEWFQYYDRSVPGKLKQGGETKETGTTIRFWADPEIFETTDYNFETVARRLQEMAFLNKGLTIELTDERVTAEEVVDDVVKDTAEAPKTADEKAAEATGPSKVKHRVFHYPGGLVDYVKHINRTKTPIQQSIIDFDGKGPGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRAALTSVVNRYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVAEPQFEGQTKTKLGNTEVKSFVQKICNEQLQHWFEANPAEAKTVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPSKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQSIITALGTGIHDEFDISKLRYHKIVLMADADVDGQHISTLLLTLLFRFMKPLVENGHIFLAQPPLYKLKWQRSEPEFAYSDRERDGLLEAGRAAGKKINVDDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVEARRSFITRNAKDVRFLDV | DNA topological change DNA-templated DNA replication chromosome; cytoplasm ATP binding DNA binding DNA negative supercoiling activity metal ion binding Mycolicibacterium smegmatis 155) 3D-structure ATP-binding Cytoplasm Direct protein sequencing DNA-binding Isomerase Magnesium Metal-binding Nucleotide-binding Reference proteome Topoisomerase MAAQKNNAPK MAAQKNNAPKEYGADSITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGFATRVDVKIHADGSVEVRDDGRGIPVEMHATGMPTIDVVMTQLHAGGKFDGETYAVSGGLHGVGVSVVNALSTRLEATVLRDGYEWFQYYDRSVPGKLKQGGETKETGTTIRFWADPEIFETTDYNFETVARRLQEMAFLNKGLTIELTDERVTAEEVVDDVVKDTAEAPKTADEKAAEATGPSKVKHRVFHYPGGLVDYVKHINRTKTPIQQSIIDFDGKGPGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRAALTSVVNRYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVAEPQFEGQTKTKLGNTEVKSFVQKICNEQLQHWFEANPAEAKTVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPSKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQSIITALGTGIHDEFDISKLRYHKIVLMADADVDGQHISTLLLTLLFRFMKPLVENGHIFLAQPPLYKLKWQRSEPEFAYSDRERDGLLEAGRAAGKKINVDDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVEARRSFITRNAKDVRFLDV |
phosphorylation regulation of cellular biosynthetic process regulation of primary metabolic process | plasma membrane | ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Mycolicibacterium smegmatis 155) | ATP-binding Cell membrane Kinase Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Transmembrane Transmembrane helix | MTTPQHLSDR | MTTPQHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEAETPNGPLPYIVMEYVDGVTLRDIVHTDGPIAPRRAIEIIADACQALNFSHQHGIIHRDVKPANIMISKNNAVKVMDFGIARALADTGNSVTQTAAVIGTAQYLSPEQARGETVDARSDVYSLGCVLYEILTGEPPFIGDSPVAVAYQHVREDPVPPSRRHADVTPELDAVVLKALAKNPDNRYQTAAEMRADLIRVHEGQAPDAPKVLTDAERTSMLAAPPADRAGAATQDMPVPRPAGYSKQRSTSVARWLIAVAVLAVLTVVVTVAINMVGGNPRNVQVPDVAEQSADDAQAALQNRGFKTVIDRQPDNEVPPGLVIGTDPEAGSELGAGEQVTINVSTGPEQALVPDVAGLTPTQARQKLKDAGFEKFRESPSPSTPEQKGRVLATNPQANQTAAIINEITIVVGAGPEDAPVLSCAGQNAESCKAILAAGGFTNTVVVEVDNPAAAGQVVGTEPADGQSVPKDTVIQIRVSKGNQFVMPDLVGQFWSDAYPRLTALGWTGVLDKGPDVRDSGQRTNAVVTQSPSAGTPVNKDAKITLSFAA | phosphorylation regulation of cellular biosynthetic process regulation of primary metabolic process plasma membrane ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity Mycolicibacterium smegmatis 155) ATP-binding Cell membrane Kinase Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Transmembrane Transmembrane helix MTTPQHLSDR MTTPQHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEAETPNGPLPYIVMEYVDGVTLRDIVHTDGPIAPRRAIEIIADACQALNFSHQHGIIHRDVKPANIMISKNNAVKVMDFGIARALADTGNSVTQTAAVIGTAQYLSPEQARGETVDARSDVYSLGCVLYEILTGEPPFIGDSPVAVAYQHVREDPVPPSRRHADVTPELDAVVLKALAKNPDNRYQTAAEMRADLIRVHEGQAPDAPKVLTDAERTSMLAAPPADRAGAATQDMPVPRPAGYSKQRSTSVARWLIAVAVLAVLTVVVTVAINMVGGNPRNVQVPDVAEQSADDAQAALQNRGFKTVIDRQPDNEVPPGLVIGTDPEAGSELGAGEQVTINVSTGPEQALVPDVAGLTPTQARQKLKDAGFEKFRESPSPSTPEQKGRVLATNPQANQTAAIINEITIVVGAGPEDAPVLSCAGQNAESCKAILAAGGFTNTVVVEVDNPAAAGQVVGTEPADGQSVPKDTVIQIRVSKGNQFVMPDLVGQFWSDAYPRLTALGWTGVLDKGPDVRDSGQRTNAVVTQSPSAGTPVNKDAKITLSFAA |
cell wall biogenesis cell wall organization mycolate cell wall layer assembly mycolic acid biosynthetic process phospholipid transport regulation of membrane potential response to antibiotic response to xenobiotic stimulus trehalose transport | cell pole; cell septum; cell tip; plasma membrane | cardiolipin binding diacylglycerol binding phosphatidylethanolamine binding phosphatidylethanolamine transfer activity phosphatidylglycerol binding phosphatidylinositol binding trehalose transmembrane transporter activity | Mycolicibacterium smegmatis 155) | 3D-structure Cell inner membrane Cell membrane Cell wall biogenesis/degradation Lipid transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MFAWWGRTVY | MFAWWGRTVYQFRYIVIGVMVALCLGGGVYGISLGNHVTQSGFYDEGSQSVAASLIGDEVYGRDRTSHVVAILTPPDDKKVTDKAWQKKVTEELDQVVKDHEDQIVGWVGWLKAPDTTDPTVSAMKTQDLRHTFISIPLQGDDDDEILKNYQVVEPELQQVNGGDIRLAGLNPLASELTGTIGEDQKRAEVAAIPLVAVVLFFVFGTVIAAALPAIIGGLAIAGALGIMRLVAEFTPVHFFAQPVVTLIGLGIAIDYGLFIVSRFREEIAEGYDTEAAVRRTVMTSGRTVVFSAVIIVASSVPLLLFPQGFLKSITYAIIASVMLAAILSITVLAAALAILGPRVDALGVTTLLKIPFLANWQFSRRIIDWFAEKTQKTKTREEVERGFWGRLVNVVMKRPIAFAAPILVVMVLLIIPLGQLSLGGISEKYLPPDNAVRQSQEQFDKLFPGFRTEPLTLVMKREDGEPITDAQIADMRAKALTVSGFTDPDNDPEKMWKERPANDSGSKDPSVRVIQNGLENRNDAAKKIDELRALQPPHGIEVFVGGTPALEQDSIHSLFDKLPLMALILIVTTTVLMFLAFGSVVLPIKAALMSALTLGSTMGILTWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVFLVSRMVEARERGMSTAEAIRIGTATTGRLITGAALILAVVAGAFVFSDLVMMKYLAFGLLIALLLDATIIRMFLVPAVMKLLGDDCWWAPRWMKRVQEKLGLGETELPDERKRPTVRESETDQRALVGVGAPPPPPRPHDPTHPAPEPVRPMPPMRSNAPSAAGTARISTPPQPPQPPQAPAQQAGDEPATTRFAMARNAVRNAVNSAVHGGAGSAAAPTERAPRPGGPAQPPAPPQREEREIESWLGALRGPAPAKNVPQPPAQPQRPSTDTTRAMPPQGRPPAGPADRGNENAPTTAFSAQRPPNGGAPADATTAIPTPPQREQEPSTEKLNTREDAPEDPETKRRGGGMSAQDLLRREGRL | cell wall biogenesis cell wall organization mycolate cell wall layer assembly mycolic acid biosynthetic process phospholipid transport regulation of membrane potential response to antibiotic response to xenobiotic stimulus trehalose transport cell pole; cell septum; cell tip; plasma membrane cardiolipin binding diacylglycerol binding phosphatidylethanolamine binding phosphatidylethanolamine transfer activity phosphatidylglycerol binding phosphatidylinositol binding trehalose transmembrane transporter activity Mycolicibacterium smegmatis 155) 3D-structure Cell inner membrane Cell membrane Cell wall biogenesis/degradation Lipid transport Membrane Reference proteome Transmembrane Transmembrane helix Transport MFAWWGRTVY MFAWWGRTVYQFRYIVIGVMVALCLGGGVYGISLGNHVTQSGFYDEGSQSVAASLIGDEVYGRDRTSHVVAILTPPDDKKVTDKAWQKKVTEELDQVVKDHEDQIVGWVGWLKAPDTTDPTVSAMKTQDLRHTFISIPLQGDDDDEILKNYQVVEPELQQVNGGDIRLAGLNPLASELTGTIGEDQKRAEVAAIPLVAVVLFFVFGTVIAAALPAIIGGLAIAGALGIMRLVAEFTPVHFFAQPVVTLIGLGIAIDYGLFIVSRFREEIAEGYDTEAAVRRTVMTSGRTVVFSAVIIVASSVPLLLFPQGFLKSITYAIIASVMLAAILSITVLAAALAILGPRVDALGVTTLLKIPFLANWQFSRRIIDWFAEKTQKTKTREEVERGFWGRLVNVVMKRPIAFAAPILVVMVLLIIPLGQLSLGGISEKYLPPDNAVRQSQEQFDKLFPGFRTEPLTLVMKREDGEPITDAQIADMRAKALTVSGFTDPDNDPEKMWKERPANDSGSKDPSVRVIQNGLENRNDAAKKIDELRALQPPHGIEVFVGGTPALEQDSIHSLFDKLPLMALILIVTTTVLMFLAFGSVVLPIKAALMSALTLGSTMGILTWMFVDGHGSGLMNYTPQPLMAPMIGLIIAVIWGLSTDYEVFLVSRMVEARERGMSTAEAIRIGTATTGRLITGAALILAVVAGAFVFSDLVMMKYLAFGLLIALLLDATIIRMFLVPAVMKLLGDDCWWAPRWMKRVQEKLGLGETELPDERKRPTVRESETDQRALVGVGAPPPPPRPHDPTHPAPEPVRPMPPMRSNAPSAAGTARISTPPQPPQPPQAPAQQAGDEPATTRFAMARNAVRNAVNSAVHGGAGSAAAPTERAPRPGGPAQPPAPPQREEREIESWLGALRGPAPAKNVPQPPAQPQRPSTDTTRAMPPQGRPPAGPADRGNENAPTTAFSAQRPPNGGAPADATTAIPTPPQREQEPSTEKLNTREDAPEDPETKRRGGGMSAQDLLRREGRL |
iron ion transport | cell outer membrane; extracellular region; pore complex | porin activity | Mycolicibacterium smegmatis 155) | 3D-structure Cell outer membrane Cell wall Direct protein sequencing Ion transport Iron Iron transport Membrane Porin Reference proteome Secreted Signal Transmembrane Transmembrane beta strand Transport | MKAISRVLIA | MKAISRVLIAMVAAIAALFTSTGTSHAGLDNELSLVDGQDRTLTVQQWDTFLNGVFPLDRNRLTREWFHSGRAKYIVAGPGADEFEGTLELGYQIGFPWSLGVGINFSYTTPNILIDDGDITAPPFGLNSVITPNLFPGVSISADLGNGPGIQEVATFSVDVSGAEGGVAVSNAHGTVTGAAGGVLLRPFARLIASTGDSVTTYGEPWNMN | iron ion transport cell outer membrane; extracellular region; pore complex porin activity Mycolicibacterium smegmatis 155) 3D-structure Cell outer membrane Cell wall Direct protein sequencing Ion transport Iron Iron transport Membrane Porin Reference proteome Secreted Signal Transmembrane Transmembrane beta strand Transport MKAISRVLIA MKAISRVLIAMVAAIAALFTSTGTSHAGLDNELSLVDGQDRTLTVQQWDTFLNGVFPLDRNRLTREWFHSGRAKYIVAGPGADEFEGTLELGYQIGFPWSLGVGINFSYTTPNILIDDGDITAPPFGLNSVITPNLFPGVSISADLGNGPGIQEVATFSVDVSGAEGGVAVSNAHGTVTGAAGGVLLRPFARLIASTGDSVTTYGEPWNMN |
proteolysis | plasma membrane | metal ion binding metalloendopeptidase activity | Mycolicibacterium smegmatis 155) | Cell membrane Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Transmembrane Transmembrane helix Zinc | MMFGIGIVLF | MMFGIGIVLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWSTRRANRLGSTEYGIKAIPLGGFCDIAGMTSVDEIAPEDRPYAMYKQKVWKRVAVLFAGPAMNFVIGLVLIYGIAIVWGLPNLHQPTTAIVGETGCVAPQITLEEMGECTGPGPAALAGIQAGDEIVKVGDTEVKDFAGMAAAVRKLDGPTRIEFKRDGRVMDTVVDVTPTQRFTSADASAPSTVGAIGVSAVPVQPPAQYNPITAVPATFAFTGDLAVELGKSLAKIPTKIGALVEAIGGGERDKETPISVVGASIIGGETVDAGLWVAFWFFLAQLNFVLGAINLVPLLPFDGGHIAVATYEKIRNMIRSARGMVAAGPVNYLKLMPATYVVLAVVAGYMLLTVTADLVNPLSIFQ | proteolysis plasma membrane metal ion binding metalloendopeptidase activity Mycolicibacterium smegmatis 155) Cell membrane Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Transmembrane Transmembrane helix Zinc MMFGIGIVLF MMFGIGIVLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWSTRRANRLGSTEYGIKAIPLGGFCDIAGMTSVDEIAPEDRPYAMYKQKVWKRVAVLFAGPAMNFVIGLVLIYGIAIVWGLPNLHQPTTAIVGETGCVAPQITLEEMGECTGPGPAALAGIQAGDEIVKVGDTEVKDFAGMAAAVRKLDGPTRIEFKRDGRVMDTVVDVTPTQRFTSADASAPSTVGAIGVSAVPVQPPAQYNPITAVPATFAFTGDLAVELGKSLAKIPTKIGALVEAIGGGERDKETPISVVGASIIGGETVDAGLWVAFWFFLAQLNFVLGAINLVPLLPFDGGHIAVATYEKIRNMIRSARGMVAAGPVNYLKLMPATYVVLAVVAGYMLLTVTADLVNPLSIFQ |
glycolipid biosynthetic process phosphatidylinositol metabolic process phospholipid biosynthetic process | plasma membrane | acyltransferase activity | Mycolicibacterium smegmatis 155) | 3D-structure Acyltransferase Cell inner membrane Cell membrane Lipid biosynthesis Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase | MTLSGRIPLG | MTLSGRIPLGGQVTDLGYAAGWRLVRAMPEAMAQGVFGAGARYAARNGGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADLSDERRARLGT | glycolipid biosynthetic process phosphatidylinositol metabolic process phospholipid biosynthetic process plasma membrane acyltransferase activity Mycolicibacterium smegmatis 155) 3D-structure Acyltransferase Cell inner membrane Cell membrane Lipid biosynthesis Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase MTLSGRIPLG MTLSGRIPLGGQVTDLGYAAGWRLVRAMPEAMAQGVFGAGARYAARNGGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADLSDERRARLGT |
glycolipid biosynthetic process phosphatidylinositol metabolic process phospholipid biosynthetic process | plasma membrane | GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity phosphatidylinositol alpha-mannosyltransferase activity | Mycolicibacterium smegmatis 155) | 3D-structure Cell membrane Glycosyltransferase Lipid biosynthesis Lipid metabolism Magnesium Membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Virulence | MRIGMVCPYS | MRIGMVCPYSFDVPGGVQSHVLQLAEVLRDAGHEVSVLAPASPHVKLPDYVVSGGKAVPIPYNGSVARLRFGPATHRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTSTTKSLTLSVFQGILRPYHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFADAPLLDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEILIVGRGDEDELREQAGDLAGHLRFLGQVDDATKASAMRSADVYCAPHLGGESFGIVLVEAMAAGTAVVASDLDAFRRVLADGDAGRLVPVDDADGMAAALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVYETVSGAGIKVQVSGAANRDETAGESV | glycolipid biosynthetic process phosphatidylinositol metabolic process phospholipid biosynthetic process plasma membrane GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity phosphatidylinositol alpha-mannosyltransferase activity Mycolicibacterium smegmatis 155) 3D-structure Cell membrane Glycosyltransferase Lipid biosynthesis Lipid metabolism Magnesium Membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Virulence MRIGMVCPYS MRIGMVCPYSFDVPGGVQSHVLQLAEVLRDAGHEVSVLAPASPHVKLPDYVVSGGKAVPIPYNGSVARLRFGPATHRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTSTTKSLTLSVFQGILRPYHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFADAPLLDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEILIVGRGDEDELREQAGDLAGHLRFLGQVDDATKASAMRSADVYCAPHLGGESFGIVLVEAMAAGTAVVASDLDAFRRVLADGDAGRLVPVDDADGMAAALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVYETVSGAGIKVQVSGAANRDETAGESV |
chromosome condensation DNA integration DNA recombination establishment of integrated proviral latency viral entry into host cell viral genome integration into host DNA | cytoplasm; nucleoid | DNA binding | Mycolicibacterium smegmatis 155) | Activator Cytoplasm Direct protein sequencing DNA condensation DNA integration DNA recombination DNA-binding Reference proteome Repressor Transcription Transcription regulation Viral genome integration Virus entry into host cell | MALPQLTDEQ | MALPQLTDEQRAAALEKAAAARRARAELKDRLKRGGTNLKQVLTDAETDEVLGKMKVSALLEALPKVGKVKAQEIMTELEIAPTRRLRGLGDRQRKALLEKFDQS | chromosome condensation DNA integration DNA recombination establishment of integrated proviral latency viral entry into host cell viral genome integration into host DNA cytoplasm; nucleoid DNA binding Mycolicibacterium smegmatis 155) Activator Cytoplasm Direct protein sequencing DNA condensation DNA integration DNA recombination DNA-binding Reference proteome Repressor Transcription Transcription regulation Viral genome integration Virus entry into host cell MALPQLTDEQ MALPQLTDEQRAAALEKAAAARRARAELKDRLKRGGTNLKQVLTDAETDEVLGKMKVSALLEALPKVGKVKAQEIMTELEIAPTRRLRGLGDRQRKALLEKFDQS |
cell division cell wall macromolecule catabolic process cell wall organization cell wall organization or biogenesis peptidoglycan catabolic process proteolysis regulation of cell shape | extracellular region | cysteine-type peptidase activity | Mycolicibacterium smegmatis 155) | Cell wall biogenesis/degradation Hydrolase Protease Reference proteome Secreted Signal Thiol protease | MRRTVRALAT | MRRTVRALATRVHGRVCAVPLVVGMLLATALYGGGPAAADPAAPDNLATLVAKVASADQKLQELGAAIQTQQETVNKAIVDVQAARDAAAAAQRELEAGQRGVADANAAIEAAQKRFDSFAAATYMNGPSRSYLTATDPADIVNTTATGQALIASSQQVMAKLQRARTEQVNRESAARLAKEKADQAARDAESSQDNAVAALKQAQQTFNAQQGELERLAAERAAAQAELDSVRKVSATGNAAPAAAPAAAPAPAAAPAPVPNSAPAPVPGAQPNPQAAAGNWDRAPSGPASSGQNWAVWDPTLPAIPSAFVSGDPIAIINAVLGIASTSAQVTADMGRSFLQKLGILPTPTGFTNGAIPRVYGREAVEYVIRRGMSQIGVPYSWGGGNAAGPSRGIDSGAGTVGFDCSGLMLYMFAGVGIKLDHYSGSQYNAGRKIPSSQMRRGDMIFYGPNASQHVAMYLGNGQMLEAPYTGSHVKVSPVRTSGMTPYVTRLIEY | cell division cell wall macromolecule catabolic process cell wall organization cell wall organization or biogenesis peptidoglycan catabolic process proteolysis regulation of cell shape extracellular region cysteine-type peptidase activity Mycolicibacterium smegmatis 155) Cell wall biogenesis/degradation Hydrolase Protease Reference proteome Secreted Signal Thiol protease MRRTVRALAT MRRTVRALATRVHGRVCAVPLVVGMLLATALYGGGPAAADPAAPDNLATLVAKVASADQKLQELGAAIQTQQETVNKAIVDVQAARDAAAAAQRELEAGQRGVADANAAIEAAQKRFDSFAAATYMNGPSRSYLTATDPADIVNTTATGQALIASSQQVMAKLQRARTEQVNRESAARLAKEKADQAARDAESSQDNAVAALKQAQQTFNAQQGELERLAAERAAAQAELDSVRKVSATGNAAPAAAPAAAPAPAAAPAPVPNSAPAPVPGAQPNPQAAAGNWDRAPSGPASSGQNWAVWDPTLPAIPSAFVSGDPIAIINAVLGIASTSAQVTADMGRSFLQKLGILPTPTGFTNGAIPRVYGREAVEYVIRRGMSQIGVPYSWGGGNAAGPSRGIDSGAGTVGFDCSGLMLYMFAGVGIKLDHYSGSQYNAGRKIPSSQMRRGDMIFYGPNASQHVAMYLGNGQMLEAPYTGSHVKVSPVRTSGMTPYVTRLIEY |
lipoprotein biosynthetic process | plasma membrane | N-acyltransferase activity | Mycolicibacterium smegmatis 155) | Acyltransferase Cell membrane Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MIPAVTDDDP | MIPAVTDDDPLEDPLDDDVAPGLDDAEPEPEPRDEHDEPSRPATGSRIGGWVARRGSRFGKGVLDRCAPLSAAIGGGLALWLSFPPIGWWFTAFPGLALLGWVLTRTATTKAGGFGYGVLFGLAFYVPLLPWISGLVGAVPWLALAFAESLFCGLFGLGAVVVVRLPGWPLWFATLWVAAEWAKSTFPFGGFPWGASSYGQTNGPLLALARIGGAPLVSFAVALIGFSLTLLTAQIVWWWRHGHKPGVPAPAVMLPGVAIAASLLVTALVWPQVRQSGTGAGDDTAVTVAAVQGNVPRLGLEFNAQRRAVLDNHVKETLRLADDVKAGRAAQPMFVIWPENSSDIDPLLNADASAQITTAAEAIDAPILVGGVVRADGYTPDNPVANNTVIVWEPTDGPGERHDKQIVQPFGEYLPWRGFFKHLSSYADRAGYFVPGTGTGVVHAAGVPIGITTCWEVIFDRAARESVLNGAQVLAVPSNNATFDEAMSAQQLAFGKLRAVEHDRYVVVAGTTGISAVIAPDGHEISRTEWFQPAYLDNQIRLKTDLTPATKWGPIVQAVLVIAGVAVLLIAILHNGRFAPRMLRRRSATTVKR | lipoprotein biosynthetic process plasma membrane N-acyltransferase activity Mycolicibacterium smegmatis 155) Acyltransferase Cell membrane Membrane Reference proteome Transferase Transmembrane Transmembrane helix MIPAVTDDDP MIPAVTDDDPLEDPLDDDVAPGLDDAEPEPEPRDEHDEPSRPATGSRIGGWVARRGSRFGKGVLDRCAPLSAAIGGGLALWLSFPPIGWWFTAFPGLALLGWVLTRTATTKAGGFGYGVLFGLAFYVPLLPWISGLVGAVPWLALAFAESLFCGLFGLGAVVVVRLPGWPLWFATLWVAAEWAKSTFPFGGFPWGASSYGQTNGPLLALARIGGAPLVSFAVALIGFSLTLLTAQIVWWWRHGHKPGVPAPAVMLPGVAIAASLLVTALVWPQVRQSGTGAGDDTAVTVAAVQGNVPRLGLEFNAQRRAVLDNHVKETLRLADDVKAGRAAQPMFVIWPENSSDIDPLLNADASAQITTAAEAIDAPILVGGVVRADGYTPDNPVANNTVIVWEPTDGPGERHDKQIVQPFGEYLPWRGFFKHLSSYADRAGYFVPGTGTGVVHAAGVPIGITTCWEVIFDRAARESVLNGAQVLAVPSNNATFDEAMSAQQLAFGKLRAVEHDRYVVVAGTTGISAVIAPDGHEISRTEWFQPAYLDNQIRLKTDLTPATKWGPIVQAVLVIAGVAVLLIAILHNGRFAPRMLRRRSATTVKR |
glycolipid biosynthetic process phosphatidylinositol metabolic process phospholipid biosynthetic process | plasma membrane | GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity phosphatidylinositol alpha-mannosyltransferase activity | Mycolicibacterium smegmatis 155) | Cell membrane Lipid biosynthesis Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Transmembrane Transmembrane helix | MRVNGYRGAK | MRVNGYRGAKVGAVDTTSPPEVPASARLQRLAPMLLVVSILARLAWTYLVPNGANFVDLHVYVGGADALDGPGALYDYVYADQTPDFPLPFTYPPFAAIVFYPLHLLPFGVVAFIWQIGIIAALYGVVRVSQRLMGLQSQRRVAMLWTALGIWTEPLRSTFDYGQVNVVLVLAVLCAVSTTRWWLSGLLVGLAAGIKLTPAVAGLYFLGARRWAAVACSAAVFFATVGVSWLVVGAQARRYFTELLGDADRIGPIGTSFNQSWRGGISRILGHDAGFGPLVLIGIGITAVLALLAWRAIGGAQDRLGGILVVSLFGLVLSPISWTHHWVWLIPLMMWLLHGPLSALRGARILGWGWLALTLLGVPWLLSFAQPTIWEIGRPWYLAWAGLVYIVATLATLGWIAFSRKGSG | glycolipid biosynthetic process phosphatidylinositol metabolic process phospholipid biosynthetic process plasma membrane GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity phosphatidylinositol alpha-mannosyltransferase activity Mycolicibacterium smegmatis 155) Cell membrane Lipid biosynthesis Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Transmembrane Transmembrane helix MRVNGYRGAK MRVNGYRGAKVGAVDTTSPPEVPASARLQRLAPMLLVVSILARLAWTYLVPNGANFVDLHVYVGGADALDGPGALYDYVYADQTPDFPLPFTYPPFAAIVFYPLHLLPFGVVAFIWQIGIIAALYGVVRVSQRLMGLQSQRRVAMLWTALGIWTEPLRSTFDYGQVNVVLVLAVLCAVSTTRWWLSGLLVGLAAGIKLTPAVAGLYFLGARRWAAVACSAAVFFATVGVSWLVVGAQARRYFTELLGDADRIGPIGTSFNQSWRGGISRILGHDAGFGPLVLIGIGITAVLALLAWRAIGGAQDRLGGILVVSLFGLVLSPISWTHHWVWLIPLMMWLLHGPLSALRGARILGWGWLALTLLGVPWLLSFAQPTIWEIGRPWYLAWAGLVYIVATLATLGWIAFSRKGSG |
cellular response to ionizing radiation double-strand break repair via nonhomologous end joining | cytoplasm | NAD+ binding NAD-dependent protein deacetylase activity protein-malonyllysine demalonylase activity protein-succinyllysine desuccinylase activity transferase activity zinc ion binding | Mycolicibacterium smegmatis 155) | Cytoplasm Direct protein sequencing DNA damage DNA repair Metal-binding NAD Reference proteome Transferase Zinc | MQVTVLSGAG | MQVTVLSGAGISAESGVPTFRDAETGLWAQVDPYEISSTDGWQRNPEKVWAWYLWRHYMMARVAPNEAHRTVAAWEDHLDVRVVTQNIDDLHERAGSTNVYHLHGSLFEFRCDACGSAFEGNLPEMPEPVETIDPPVCPCSGLIRPSVVWFGEPLPDAAWNRSVLAVSSADVVIVVGTSSIVYPAAGLPEAALAAGKPVIEVNPERTPLSDSATVSLRETASEALPTLLQRLPELLNRSA | cellular response to ionizing radiation double-strand break repair via nonhomologous end joining cytoplasm NAD+ binding NAD-dependent protein deacetylase activity protein-malonyllysine demalonylase activity protein-succinyllysine desuccinylase activity transferase activity zinc ion binding Mycolicibacterium smegmatis 155) Cytoplasm Direct protein sequencing DNA damage DNA repair Metal-binding NAD Reference proteome Transferase Zinc MQVTVLSGAG MQVTVLSGAGISAESGVPTFRDAETGLWAQVDPYEISSTDGWQRNPEKVWAWYLWRHYMMARVAPNEAHRTVAAWEDHLDVRVVTQNIDDLHERAGSTNVYHLHGSLFEFRCDACGSAFEGNLPEMPEPVETIDPPVCPCSGLIRPSVVWFGEPLPDAAWNRSVLAVSSADVVIVVGTSSIVYPAAGLPEAALAAGKPVIEVNPERTPLSDSATVSLRETASEALPTLLQRLPELLNRSA |
capsule polysaccharide biosynthetic process cell wall organization response to antibiotic | membrane; periplasmic space | D-arabinono-1,4-lactone oxidase activity FAD binding | Mycolicibacterium smegmatis 155) | 3D-structure Antibiotic resistance Cell wall biogenesis/degradation FAD Flavoprotein Nucleotide-binding Oxidoreductase Periplasm Reference proteome | MSTTEFPTTT | MSTTEFPTTTKRLMGWGRTAPTVASVLSTSDPEVIVRAVTRAAEEGGRGVIARGLGRSYGDNAQNGGGLVIDMPALNRIHSIDSGTRLVDVDAGVSLDQLMKAALPHGLWVPVLPGTRQVTVGGAIGCDIHGKNHHSAGSFGNHVRSMELLTANGEVRHLTPAGPDSDLFWATVGGNGLTGIILRATIEMTPTETAYFIADGDVTGSLDETIAFHSDGSEANYTYSSAWFDAISKPPKLGRAAISRGSLAKLDQLPSKLQKDPLKFDAPQLLTLPDIFPNGLANKFTFMPIGELWYRKSGTYRNKVQNLTQFYHPLDMFGEWNRAYGSAGFLQYQFVVPTEAVEEFKSIIVDIQRSGHYSFLNVFKLFGPGNQAPLSFPIPGWNVCVDFPIKAGLHEFVTELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRIDEWIRIRRSVDPDGVFASDMARRLQLL | capsule polysaccharide biosynthetic process cell wall organization response to antibiotic membrane; periplasmic space D-arabinono-1,4-lactone oxidase activity FAD binding Mycolicibacterium smegmatis 155) 3D-structure Antibiotic resistance Cell wall biogenesis/degradation FAD Flavoprotein Nucleotide-binding Oxidoreductase Periplasm Reference proteome MSTTEFPTTT MSTTEFPTTTKRLMGWGRTAPTVASVLSTSDPEVIVRAVTRAAEEGGRGVIARGLGRSYGDNAQNGGGLVIDMPALNRIHSIDSGTRLVDVDAGVSLDQLMKAALPHGLWVPVLPGTRQVTVGGAIGCDIHGKNHHSAGSFGNHVRSMELLTANGEVRHLTPAGPDSDLFWATVGGNGLTGIILRATIEMTPTETAYFIADGDVTGSLDETIAFHSDGSEANYTYSSAWFDAISKPPKLGRAAISRGSLAKLDQLPSKLQKDPLKFDAPQLLTLPDIFPNGLANKFTFMPIGELWYRKSGTYRNKVQNLTQFYHPLDMFGEWNRAYGSAGFLQYQFVVPTEAVEEFKSIIVDIQRSGHYSFLNVFKLFGPGNQAPLSFPIPGWNVCVDFPIKAGLHEFVTELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRIDEWIRIRRSVDPDGVFASDMARRLQLL |
modulation of receptor activity in another organism | extracellular region | acetylcholine receptor inhibitor activity ion channel regulator activity toxin activity | Boiga irregularis | 3D-structure Acetylcholine receptor inhibiting toxin Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Postsynaptic neurotoxin Pyrrolidone carboxylic acid Secreted Signal Toxin | MKTLLLAVAV | MKTLLLAVAVVAFVCLGSADQLGLGRQQIDWGQGQAVGPPYTLCFECNRMTSSDCSTALRCYRGSCYTLYRPDENCELKWAVKGCAETCPTAGPNERVKCCRSPRCNDD | modulation of receptor activity in another organism extracellular region acetylcholine receptor inhibitor activity ion channel regulator activity toxin activity Boiga irregularis 3D-structure Acetylcholine receptor inhibiting toxin Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Postsynaptic neurotoxin Pyrrolidone carboxylic acid Secreted Signal Toxin MKTLLLAVAV MKTLLLAVAVVAFVCLGSADQLGLGRQQIDWGQGQAVGPPYTLCFECNRMTSSDCSTALRCYRGSCYTLYRPDENCELKWAVKGCAETCPTAGPNERVKCCRSPRCNDD |
modulation of receptor activity in another organism | extracellular region | acetylcholine receptor inhibitor activity ion channel regulator activity toxin activity | Boiga irregularis | 3D-structure Acetylcholine receptor inhibiting toxin Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Postsynaptic neurotoxin Pyrrolidone carboxylic acid Secreted Signal Toxin | MKTLLLAVAV | MKTLLLAVAVVAFVCLGSADQLGLGRQQIDWGKGQAKGPPYTLCFECNRETCSNCFKDNRCPPYHRTCYTLYRPDGNGEMKWAVKGCAKTCPTAQPGESVQCCNTPKCNDY | modulation of receptor activity in another organism extracellular region acetylcholine receptor inhibitor activity ion channel regulator activity toxin activity Boiga irregularis 3D-structure Acetylcholine receptor inhibiting toxin Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Postsynaptic neurotoxin Pyrrolidone carboxylic acid Secreted Signal Toxin MKTLLLAVAV MKTLLLAVAVVAFVCLGSADQLGLGRQQIDWGKGQAKGPPYTLCFECNRETCSNCFKDNRCPPYHRTCYTLYRPDGNGEMKWAVKGCAKTCPTAQPGESVQCCNTPKCNDY |
abscisic acid-activated signaling pathway DNA-templated transcription regulation of seed dormancy process seed dormancy process sugar mediated signaling pathway | nucleus | identical protein binding sequence-specific DNA binding | Arabidopsis thaliana | Activator Alternative splicing Germination Nucleus Reference proteome Transcription Transcription regulation | MGSSSKNIEQ | MGSSSKNIEQAQDSYLEWMSLQSQRIPELKQLLAQRRSHGDEDNDNKLRKLTGKIIGDFKNYAAKRADLAHRCSSNYYAPTWNSPLENALIWMGGCRPSSFFRLVYALCGSQTEIRVTQFLRNIDGYESSGGGGGASLSDLSAEQLAKINVLHVKIIDEEEKMTKKVSSLQEDAADIPIATVAYEMENVGEPNVVVDQALDKQEEAMARLLVEADNLRVDTLAKILGILSPVQGADFLLAGKKLHLSMHEWGTMRDRRRRDCMVDTEVIFDACTTVNSGPRPTETTNNERN | abscisic acid-activated signaling pathway DNA-templated transcription regulation of seed dormancy process seed dormancy process sugar mediated signaling pathway nucleus identical protein binding sequence-specific DNA binding Arabidopsis thaliana Activator Alternative splicing Germination Nucleus Reference proteome Transcription Transcription regulation MGSSSKNIEQ MGSSSKNIEQAQDSYLEWMSLQSQRIPELKQLLAQRRSHGDEDNDNKLRKLTGKIIGDFKNYAAKRADLAHRCSSNYYAPTWNSPLENALIWMGGCRPSSFFRLVYALCGSQTEIRVTQFLRNIDGYESSGGGGGASLSDLSAEQLAKINVLHVKIIDEEEKMTKKVSSLQEDAADIPIATVAYEMENVGEPNVVVDQALDKQEEAMARLLVEADNLRVDTLAKILGILSPVQGADFLLAGKKLHLSMHEWGTMRDRRRRDCMVDTEVIFDACTTVNSGPRPTETTNNERN |
cell population proliferation negative regulation of cell population proliferation positive regulation of prostaglandin secretion prostaglandin biosynthetic process regulation of fever generation regulation of inflammatory response sensory perception of pain | membrane; nuclear envelope lumen; perinuclear region of cytoplasm | glutathione binding glutathione peroxidase activity glutathione transferase activity prostaglandin-D synthase activity prostaglandin-E synthase activity | Canis lupus familiaris | Cytoplasm Fatty acid biosynthesis Fatty acid metabolism Isomerase Lipid biosynthesis Lipid metabolism Membrane Oxidoreductase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome Transferase Transmembrane Transmembrane helix | MPPPVLALVS | MPPPVLALVSGQALPAFLLCSTLLVIKMYVVAVITGQVRLRKKAFANPEDALRHGGLQYCRSDQDVDRCLRAHRNDMETIYPFLFLGFVYSFLGPDPFIAQMHFLVFFLGRMVHTVAYLGKLRAPTRSLAYTVAQLPCASMALQIVWEAACHL | cell population proliferation negative regulation of cell population proliferation positive regulation of prostaglandin secretion prostaglandin biosynthetic process regulation of fever generation regulation of inflammatory response sensory perception of pain membrane; nuclear envelope lumen; perinuclear region of cytoplasm glutathione binding glutathione peroxidase activity glutathione transferase activity prostaglandin-D synthase activity prostaglandin-E synthase activity Canis lupus familiaris Cytoplasm Fatty acid biosynthesis Fatty acid metabolism Isomerase Lipid biosynthesis Lipid metabolism Membrane Oxidoreductase Prostaglandin biosynthesis Prostaglandin metabolism Reference proteome Transferase Transmembrane Transmembrane helix MPPPVLALVS MPPPVLALVSGQALPAFLLCSTLLVIKMYVVAVITGQVRLRKKAFANPEDALRHGGLQYCRSDQDVDRCLRAHRNDMETIYPFLFLGFVYSFLGPDPFIAQMHFLVFFLGRMVHTVAYLGKLRAPTRSLAYTVAQLPCASMALQIVWEAACHL |
angioblast cell migration from lateral mesoderm to midline blood vessel development cardiac muscle tissue development cell migration coronary vasculature development determination of heart left/right asymmetry determination of liver left/right asymmetry endodermal cell differentiation establishment of epithelial cell polarity G protein-coupled receptor signaling pathway gastrulation gastrulation with mouth forming second heart development mesodermal cell migration negative regulation of cAMP-mediated signaling positive regulation of angiogenesis positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation of inhibitory G protein-coupled receptor phosphorylation positive regulation of release of sequestered calcium ion into cytosol regulation of nodal signaling pathway sprouting angiogenesis vasculogenesis | plasma membrane | apelin receptor activity | Danio rerio | Angiogenesis Cell membrane Developmental protein G-protein coupled receptor Gastrulation Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNAMDNMTAD | MNAMDNMTADYSPDYFDDAVNSSMCEYDEWEPSYSLIPVLYMLIFILGLTGNGVVIFTVWRAQSKRRAADVYIGNLALADLTFVVTLPLWAVYTALGYHWPFGVALCKISSYVVLLNMYASVFCLTCLSLDRYMAIVHSLTSTQLRTRGHMRASLTAIWLLSGVLAAPTLLFRTTVYDVETNRTSCAMDFNLVVSQPGQETYWIAGLSISSTALGFLIPLLAMMVCYGFIGCTVTRHFNSLRKEDQRKRRLLKIITTLVVVFAACWMPFHVVKTMDALSYLNLAPDSCTFLNLLLLAHPYATCLAYVNSCLNPLLYAFFDLRFRSQCLCLLNLKKALHASPASSLSSQKTEAQSLATKV | angioblast cell migration from lateral mesoderm to midline blood vessel development cardiac muscle tissue development cell migration coronary vasculature development determination of heart left/right asymmetry determination of liver left/right asymmetry endodermal cell differentiation establishment of epithelial cell polarity G protein-coupled receptor signaling pathway gastrulation gastrulation with mouth forming second heart development mesodermal cell migration negative regulation of cAMP-mediated signaling positive regulation of angiogenesis positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation of inhibitory G protein-coupled receptor phosphorylation positive regulation of release of sequestered calcium ion into cytosol regulation of nodal signaling pathway sprouting angiogenesis vasculogenesis plasma membrane apelin receptor activity Danio rerio Angiogenesis Cell membrane Developmental protein G-protein coupled receptor Gastrulation Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix MNAMDNMTAD MNAMDNMTADYSPDYFDDAVNSSMCEYDEWEPSYSLIPVLYMLIFILGLTGNGVVIFTVWRAQSKRRAADVYIGNLALADLTFVVTLPLWAVYTALGYHWPFGVALCKISSYVVLLNMYASVFCLTCLSLDRYMAIVHSLTSTQLRTRGHMRASLTAIWLLSGVLAAPTLLFRTTVYDVETNRTSCAMDFNLVVSQPGQETYWIAGLSISSTALGFLIPLLAMMVCYGFIGCTVTRHFNSLRKEDQRKRRLLKIITTLVVVFAACWMPFHVVKTMDALSYLNLAPDSCTFLNLLLLAHPYATCLAYVNSCLNPLLYAFFDLRFRSQCLCLLNLKKALHASPASSLSSQKTEAQSLATKV |
cellulose catabolic process galactomannan metabolic process glucomannan metabolic process mannan catabolic process | extracellular region | cellulase activity mannan binding mannan endo-1,4-beta-mannosidase activity | Bifidobacterium adolescentis | Carbohydrate metabolism Cell wall Glycosidase Hydrolase Peptidoglycan-anchor Polysaccharide degradation Reference proteome Repeat Secreted Signal | MKTTVTKLLA | MKTTVTKLLATVAAASTIFGMSTLPAFAAEGKSASNGNSVNISDVNATAETRALFDKLKNSGKGDLRFGQQHATDENISSSASQGDVYETTGKYPAVFGWDAGLALRGAEKPGSGADKNANAKALAQNITDADSKGAIVTLSAHWCNPGTGKDFNDTTAVASELLPGGKYSGTFNKELDAIAATAQRAKRSDGTLIPIIFRPLHENNGSWFWWGATHASASEYKELYRYIVDYLRDVKDVHNLLYAYSPGGVFNGDSTDYLATYPGDQWVDVLGYDEYDSDDSADDSSAWINTVVKDMKMVSDQASQRGKIVALTEFGRSGDRKFKESGTGDKDTKFFSELAEALAENVPSTAYMMTWANFGGGGDNFQAYTSWKGSDGEADFKAFADSNKNLMASKDNVDYSNAPAAAMQNGSARIVTPVDGNRVTDTKVVVRVKTEGVKYSDLDLNSAIVTTDRGQNVKLKYSCNGYFTGILDLNAAGINLDQSKLTLTPQVKTKDGKTLAAADGNGSVTVKLGAKPEQTVDNVEDFDSYDNEAELQSVYSPSHSTKSNLTLVDSPEDNGTKAGNIHYDFVSYPEYNGFQRSHTPKQDWSGFSKLNMFLKADGSDHKFVVQVNAGGVTFEAYPKIDGTDGHVVSLNFGDADGNGGDFAPASWDTAHAGMKLSQKLLSKVGSFALYINDNGGNRPKSGDLTLDSIKLDGKRDAYAPNTNPTPGNTAKAQSVDDFSGYSDDAAAQSAWGNRGHTEVLSLDEGPTDGSKALRFKYDFSNGGWYDVAKYLDGANWSGESVLAFQVKGDGSGNAIGLQIGTSDGKYFLASVKLDFTGWKQIEIPLVDNANLTQSWPEDANKDNPMTEDDLASIKELVFASQQWNSESDGLDSSIADIKVEPAENTSNEQTPKDESKTEVKADKEQEQSEDTSADVTAQDPATCPISDEDSKGSTGNTTVTVKPTPDTKEPADNTGKDGLSRTGSNIISAIAAVAVLLLGGCAVLIARKRKGGDIE | cellulose catabolic process galactomannan metabolic process glucomannan metabolic process mannan catabolic process extracellular region cellulase activity mannan binding mannan endo-1,4-beta-mannosidase activity Bifidobacterium adolescentis Carbohydrate metabolism Cell wall Glycosidase Hydrolase Peptidoglycan-anchor Polysaccharide degradation Reference proteome Repeat Secreted Signal MKTTVTKLLA MKTTVTKLLATVAAASTIFGMSTLPAFAAEGKSASNGNSVNISDVNATAETRALFDKLKNSGKGDLRFGQQHATDENISSSASQGDVYETTGKYPAVFGWDAGLALRGAEKPGSGADKNANAKALAQNITDADSKGAIVTLSAHWCNPGTGKDFNDTTAVASELLPGGKYSGTFNKELDAIAATAQRAKRSDGTLIPIIFRPLHENNGSWFWWGATHASASEYKELYRYIVDYLRDVKDVHNLLYAYSPGGVFNGDSTDYLATYPGDQWVDVLGYDEYDSDDSADDSSAWINTVVKDMKMVSDQASQRGKIVALTEFGRSGDRKFKESGTGDKDTKFFSELAEALAENVPSTAYMMTWANFGGGGDNFQAYTSWKGSDGEADFKAFADSNKNLMASKDNVDYSNAPAAAMQNGSARIVTPVDGNRVTDTKVVVRVKTEGVKYSDLDLNSAIVTTDRGQNVKLKYSCNGYFTGILDLNAAGINLDQSKLTLTPQVKTKDGKTLAAADGNGSVTVKLGAKPEQTVDNVEDFDSYDNEAELQSVYSPSHSTKSNLTLVDSPEDNGTKAGNIHYDFVSYPEYNGFQRSHTPKQDWSGFSKLNMFLKADGSDHKFVVQVNAGGVTFEAYPKIDGTDGHVVSLNFGDADGNGGDFAPASWDTAHAGMKLSQKLLSKVGSFALYINDNGGNRPKSGDLTLDSIKLDGKRDAYAPNTNPTPGNTAKAQSVDDFSGYSDDAAAQSAWGNRGHTEVLSLDEGPTDGSKALRFKYDFSNGGWYDVAKYLDGANWSGESVLAFQVKGDGSGNAIGLQIGTSDGKYFLASVKLDFTGWKQIEIPLVDNANLTQSWPEDANKDNPMTEDDLASIKELVFASQQWNSESDGLDSSIADIKVEPAENTSNEQTPKDESKTEVKADKEQEQSEDTSADVTAQDPATCPISDEDSKGSTGNTTVTVKPTPDTKEPADNTGKDGLSRTGSNIISAIAAVAVLLLGGCAVLIARKRKGGDIE |
carbohydrate metabolic process | beta-galactosidase complex | beta-galactosidase activity | Bifidobacterium adolescentis | 3D-structure Direct protein sequencing Glycosidase Hydrolase Reference proteome | MSARRNFEWP | MSARRNFEWPELLTADGRGIAFGGDYNPDQWSEDIWDDDIRLMKQAGVNTVALAIFSWDRIQPTEDRWDFGWLDRIIDKLGNAGIVVDLASATATAPLWLYESHPEVLPRDKYGHPVNAGSRQSWSPTSPVFKEYALTLCRKLAERYGTNPYVTAWHMGNEYGWNNREDYSDNALEAFRAWCRRKYGTIDALNQAWGTTFWGQEMNGFDEVLIPRFMGADSMVNPGQKLDFERFGNDMLLDFYKAERDAIAEICPDKPFTTNFMVSTDQCCMDYAAWAKEVNFVSNDHYFHEGESHLDELACSDALMDSLALGKPWYVMEHSTSAVQWKPLNTRKRKGETVRDSLAHVAMGADAINFFQWRASAFGAEAFHSAMVPHAGEDTKLFRQVCELGASLHTLADAGVQGTELAHSDTAILFSAESEWATRSQTLPSMKLNHWHDVRDWYRAFLDAGSRADIVPLAYDWSSYKTVVLPTVLILSAADTQRLADFAAAGGRVVVGYATGLIDEHFHTWLGGYPGAGDGLLRSMLGVRGEEFNILGAEAEGEPGEIRLSSADDSAALDGTTTRLWQNDVNVTGEHAQVLATYAGEEADEWELDGTAAVTRNPYGSGEAYFVGCDLDVADLTKLVRAYLAASSQENADVLHTVRASADATFDFYLPRGKKTVELQGIEGEPVILFQTDREEKPGSYTVRRNGVLVVRR | carbohydrate metabolic process beta-galactosidase complex beta-galactosidase activity Bifidobacterium adolescentis 3D-structure Direct protein sequencing Glycosidase Hydrolase Reference proteome MSARRNFEWP MSARRNFEWPELLTADGRGIAFGGDYNPDQWSEDIWDDDIRLMKQAGVNTVALAIFSWDRIQPTEDRWDFGWLDRIIDKLGNAGIVVDLASATATAPLWLYESHPEVLPRDKYGHPVNAGSRQSWSPTSPVFKEYALTLCRKLAERYGTNPYVTAWHMGNEYGWNNREDYSDNALEAFRAWCRRKYGTIDALNQAWGTTFWGQEMNGFDEVLIPRFMGADSMVNPGQKLDFERFGNDMLLDFYKAERDAIAEICPDKPFTTNFMVSTDQCCMDYAAWAKEVNFVSNDHYFHEGESHLDELACSDALMDSLALGKPWYVMEHSTSAVQWKPLNTRKRKGETVRDSLAHVAMGADAINFFQWRASAFGAEAFHSAMVPHAGEDTKLFRQVCELGASLHTLADAGVQGTELAHSDTAILFSAESEWATRSQTLPSMKLNHWHDVRDWYRAFLDAGSRADIVPLAYDWSSYKTVVLPTVLILSAADTQRLADFAAAGGRVVVGYATGLIDEHFHTWLGGYPGAGDGLLRSMLGVRGEEFNILGAEAEGEPGEIRLSSADDSAALDGTTTRLWQNDVNVTGEHAQVLATYAGEEADEWELDGTAAVTRNPYGSGEAYFVGCDLDVADLTKLVRAYLAASSQENADVLHTVRASADATFDFYLPRGKKTVELQGIEGEPVILFQTDREEKPGSYTVRRNGVLVVRR |
B cell apoptotic process B cell homeostasis epithelial cell migration hyperosmotic response intracellular signal transduction negative regulation of B cell proliferation negative regulation of protein phosphorylation post-translational protein modification protein phosphorylation regulation of cell motility regulation of germinal center formation regulation of immunoglobulin production regulation of transcription by RNA polymerase II renal system process spleen development | cleavage furrow; cytoplasm; endosome; midbody; nucleus; protein-containing complex | ATP binding chromatin binding diacylglycerol-dependent serine/threonine kinase activity histone binding histone deacetylase binding histone H3T11 kinase activity nuclear androgen receptor binding nuclear receptor coactivator activity protein kinase C binding protein serine kinase activity protein serine/threonine kinase activity small GTPase binding | Bos taurus | Acetylation ATP-binding Cell membrane Chromatin regulator Coiled coil Cytoplasm Endosome Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transcription Transcription regulation Transferase | MASDAVQSEP | MASDAVQSEPRSWSLLEQLGLAGADLAAPGVQQQLELERERLRREIRKELKLKEGAENLRRATTDLGRNLGPVELVLRGSSRRLALLHQQLQELHAHVVLPDPAVGVHDAPQSPGTGDSACSATNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDIIRMQLHRALQACQLESQAAPDEAQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPADHPKGRLLREELAAASSAAFSARLAGPFPATHYSTLSKPAPLTGTLEVRVVGCRDLPETIPWNPSPSVGGPGTPDSRTPFLSRPARGLYSRTGSLSGRSSLKAEAENTNEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPNATATGTFSPGASPGPEARSTGDISVEKLNLGTETDSSPQKSPLGPPSSPSSLSSPIQATTTTPELPSETQETPGPTLCSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTNAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWDALLARRLPPPFVPTLAGRTDVSNFDEEFTGEAPTLSPPRDARPLTATEQAAFRDFDFVAGSC | B cell apoptotic process B cell homeostasis epithelial cell migration hyperosmotic response intracellular signal transduction negative regulation of B cell proliferation negative regulation of protein phosphorylation post-translational protein modification protein phosphorylation regulation of cell motility regulation of germinal center formation regulation of immunoglobulin production regulation of transcription by RNA polymerase II renal system process spleen development cleavage furrow; cytoplasm; endosome; midbody; nucleus; protein-containing complex ATP binding chromatin binding diacylglycerol-dependent serine/threonine kinase activity histone binding histone deacetylase binding histone H3T11 kinase activity nuclear androgen receptor binding nuclear receptor coactivator activity protein kinase C binding protein serine kinase activity protein serine/threonine kinase activity small GTPase binding Bos taurus Acetylation ATP-binding Cell membrane Chromatin regulator Coiled coil Cytoplasm Endosome Kinase Membrane Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transcription Transcription regulation Transferase MASDAVQSEP MASDAVQSEPRSWSLLEQLGLAGADLAAPGVQQQLELERERLRREIRKELKLKEGAENLRRATTDLGRNLGPVELVLRGSSRRLALLHQQLQELHAHVVLPDPAVGVHDAPQSPGTGDSACSATNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDIIRMQLHRALQACQLESQAAPDEAQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPADHPKGRLLREELAAASSAAFSARLAGPFPATHYSTLSKPAPLTGTLEVRVVGCRDLPETIPWNPSPSVGGPGTPDSRTPFLSRPARGLYSRTGSLSGRSSLKAEAENTNEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPNATATGTFSPGASPGPEARSTGDISVEKLNLGTETDSSPQKSPLGPPSSPSSLSSPIQATTTTPELPSETQETPGPTLCSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTNAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWDALLARRLPPPFVPTLAGRTDVSNFDEEFTGEAPTLSPPRDARPLTATEQAAFRDFDFVAGSC |
DNA damage checkpoint signaling DNA repair erythrocyte differentiation hematopoietic stem cell differentiation negative regulation of IRE1-mediated unfolded protein response negative regulation of NF-kappaB transcription factor activity negative regulation of protein ubiquitination positive regulation of autophagy protein K69-linked ufmylation protein ufmylation regulation of canonical NF-kappaB signal transduction regulation of inflammatory response regulation of intracellular estrogen receptor signaling pathway regulation of proteasomal ubiquitin-dependent protein catabolic process response to endoplasmic reticulum stress reticulophagy | cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; nucleus; site of double-strand break | UFM1 ligase activity UFM1 transferase activity | Bos taurus | Acetylation Chromosome Cytoplasm DNA damage DNA repair Endoplasmic reticulum Membrane Methylation Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation Ubl conjugation pathway | MADAWEEIRR | MADAWEEIRRLAADFQRAQFAEATQRLSERNCIEIVNKLIAQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQAINVDLTHIENRIGDIVKSEKHVQLVLGQLIDENYLDRLAEEVNDKLQESGQVTIAELCKTYDLPGNFLTQALTQRLGRIINGHIDLDNRGVIFTEAFVSRHKARIRGLFSAITRPTAVNSLISRYGFQEQLLYSVLEELVNDGRLRGTVVGGRQDKAVFIPDIYSRTQSTWVDSFLRQNGYLEFDALSRLGIPDAMSYIKKRYKTTQLLFLKAACVGQGLVDQVEASVEEAISSGTWVDIAPLLPSSLSVEDAAILLQHVMRALSKQASAVVFSDTIVVSEKFINDCTDLFSELMHQKAEKEMKNNPVHLITEEDLKQISILESINTSKKDKKDERRRKATEGSGSVRGGGGSNAREYKIKKTKKKGRKDDDSDDESSHTGKKKPEITFMFQDEIEDFLRKHLQDAPEEFISELAEYLIKPLNKTYLEVVHSVYMSSTSSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKFFTDDTQAALTKHLLKTVCTDITNLVFNFLASDLMMAVDDPATITSEVRKKILSKLSEETKVALTKLHNSLNEKSIEDFLACLDSAAEACDIMLKKGDKKRERQVLFQHRQALVEQLKVTEDPALTLHLTSVLLFQFSTHSMLHAPGRCVPQIIAFLSSKIPEDQHALLVKYQGLVVKHLVSQNKKTGQGEDPLSDELDKEQEDIINTTRKELQELSSSIKDLVLKSRKSSVTEE | DNA damage checkpoint signaling DNA repair erythrocyte differentiation hematopoietic stem cell differentiation negative regulation of IRE1-mediated unfolded protein response negative regulation of NF-kappaB transcription factor activity negative regulation of protein ubiquitination positive regulation of autophagy protein K69-linked ufmylation protein ufmylation regulation of canonical NF-kappaB signal transduction regulation of inflammatory response regulation of intracellular estrogen receptor signaling pathway regulation of proteasomal ubiquitin-dependent protein catabolic process response to endoplasmic reticulum stress reticulophagy cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; nucleus; site of double-strand break UFM1 ligase activity UFM1 transferase activity Bos taurus Acetylation Chromosome Cytoplasm DNA damage DNA repair Endoplasmic reticulum Membrane Methylation Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation Ubl conjugation pathway MADAWEEIRR MADAWEEIRRLAADFQRAQFAEATQRLSERNCIEIVNKLIAQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQAINVDLTHIENRIGDIVKSEKHVQLVLGQLIDENYLDRLAEEVNDKLQESGQVTIAELCKTYDLPGNFLTQALTQRLGRIINGHIDLDNRGVIFTEAFVSRHKARIRGLFSAITRPTAVNSLISRYGFQEQLLYSVLEELVNDGRLRGTVVGGRQDKAVFIPDIYSRTQSTWVDSFLRQNGYLEFDALSRLGIPDAMSYIKKRYKTTQLLFLKAACVGQGLVDQVEASVEEAISSGTWVDIAPLLPSSLSVEDAAILLQHVMRALSKQASAVVFSDTIVVSEKFINDCTDLFSELMHQKAEKEMKNNPVHLITEEDLKQISILESINTSKKDKKDERRRKATEGSGSVRGGGGSNAREYKIKKTKKKGRKDDDSDDESSHTGKKKPEITFMFQDEIEDFLRKHLQDAPEEFISELAEYLIKPLNKTYLEVVHSVYMSSTSSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKFFTDDTQAALTKHLLKTVCTDITNLVFNFLASDLMMAVDDPATITSEVRKKILSKLSEETKVALTKLHNSLNEKSIEDFLACLDSAAEACDIMLKKGDKKRERQVLFQHRQALVEQLKVTEDPALTLHLTSVLLFQFSTHSMLHAPGRCVPQIIAFLSSKIPEDQHALLVKYQGLVVKHLVSQNKKTGQGEDPLSDELDKEQEDIINTTRKELQELSSSIKDLVLKSRKSSVTEE |
canonical glycolysis fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process glycolytic process negative regulation of insulin secretion response to glucose | 6-phosphofructokinase complex; membrane | 6-phosphofructokinase activity AMP binding ATP binding fructose binding fructose-6-phosphate binding identical protein binding kinase binding metal ion binding monosaccharide binding | Bos taurus | Acetylation Allosteric enzyme ATP-binding Cytoplasm Glycolysis Glycoprotein Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Transferase | MASVDLEKLR | MASVDLEKLRTTGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTVIGSARCKAFTTREGRRAAAYNLVQRGITNLCVIGGDGSLTGANIFRSEWGSLLEELVSEGKISEGTAQTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSRYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQMTKEVQKAMDEKRFDEAIQLRGGSFENNWNIYKLLSHQKISKEKTNFSLAILNVGAPAAGMNAAVRSAVRSGISQGHTVYVVHDGFEGLAKNQVQEVSWHDVAGWLGRGGSMLGTKRTLPKGFMEKIVENIRLHNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIQDLKANVEHMTEKMKTEIQRGLVLRNEKCHEHYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAIIWMSEKLRAVYRNGRVFANASDSACVIGLQKKVVAFSPVTELKKDTDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIETGF | canonical glycolysis fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process glycolytic process negative regulation of insulin secretion response to glucose 6-phosphofructokinase complex; membrane 6-phosphofructokinase activity AMP binding ATP binding fructose binding fructose-6-phosphate binding identical protein binding kinase binding metal ion binding monosaccharide binding Bos taurus Acetylation Allosteric enzyme ATP-binding Cytoplasm Glycolysis Glycoprotein Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Transferase MASVDLEKLR MASVDLEKLRTTGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTVIGSARCKAFTTREGRRAAAYNLVQRGITNLCVIGGDGSLTGANIFRSEWGSLLEELVSEGKISEGTAQTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSRYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQMTKEVQKAMDEKRFDEAIQLRGGSFENNWNIYKLLSHQKISKEKTNFSLAILNVGAPAAGMNAAVRSAVRSGISQGHTVYVVHDGFEGLAKNQVQEVSWHDVAGWLGRGGSMLGTKRTLPKGFMEKIVENIRLHNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIQDLKANVEHMTEKMKTEIQRGLVLRNEKCHEHYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAIIWMSEKLRAVYRNGRVFANASDSACVIGLQKKVVAFSPVTELKKDTDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIETGF |
chemotaxis estrous cycle immune response phosphatidylcholine catabolic process phospholipid catabolic process sphingolipid catabolic process | extracellular space | alkylglycerophosphoethanolamine phosphodiesterase activity calcium ion binding lysophospholipase activity nucleic acid binding phosphodiesterase I activity polysaccharide binding scavenger receptor activity zinc ion binding | Bos taurus | Calcium Chemotaxis Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Metal-binding Obesity Reference proteome Repeat Secreted Signal Zinc | MARRRSCQLH | MARRRSCQLHQVISLFTFAVGVNICLGVTANRIKRAEGWGEGPPTVLSDSPSINISGSCKGRCFELQEAGPPDCRCDNLCKSYSSCCLDFDELCLKTAGGWECTKDRCGEVRNEDHACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKTPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDAHFNLRGREKFNHRWWGGQPLWITATKQGVIAGTFFWPVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLRDIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDIILVPGTLGRIRPKFNNHAKYDPKVIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDVHLLVERRWHVARKPLEVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTVPEEVTRPNYPGVMYLQSDFDLGCTCDDKAEPKNKLDELNKHLHIKESTEAETRKFRGSKNEIKENVNGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQADVSDIPAHLTNCVRPDVRVSPSFSQSCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRIWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTQDKIKQYVEGSSVPVPTHYYSILTSCLDFTQPADRCDGPLSVSAFVLPHRPDNDESCNSSEDESKWVEELLKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLQTYESEI | chemotaxis estrous cycle immune response phosphatidylcholine catabolic process phospholipid catabolic process sphingolipid catabolic process extracellular space alkylglycerophosphoethanolamine phosphodiesterase activity calcium ion binding lysophospholipase activity nucleic acid binding phosphodiesterase I activity polysaccharide binding scavenger receptor activity zinc ion binding Bos taurus Calcium Chemotaxis Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Metal-binding Obesity Reference proteome Repeat Secreted Signal Zinc MARRRSCQLH MARRRSCQLHQVISLFTFAVGVNICLGVTANRIKRAEGWGEGPPTVLSDSPSINISGSCKGRCFELQEAGPPDCRCDNLCKSYSSCCLDFDELCLKTAGGWECTKDRCGEVRNEDHACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKTPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDAHFNLRGREKFNHRWWGGQPLWITATKQGVIAGTFFWPVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLRDIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDIILVPGTLGRIRPKFNNHAKYDPKVIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDVHLLVERRWHVARKPLEVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTVPEEVTRPNYPGVMYLQSDFDLGCTCDDKAEPKNKLDELNKHLHIKESTEAETRKFRGSKNEIKENVNGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQADVSDIPAHLTNCVRPDVRVSPSFSQSCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRIWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTQDKIKQYVEGSSVPVPTHYYSILTSCLDFTQPADRCDGPLSVSAFVLPHRPDNDESCNSSEDESKWVEELLKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLQTYESEI |
fatty acid metabolic process phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of mitochondrial membrane permeability involved in apoptotic process | cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; ruffle membrane | myristoyl-CoA hydrolase activity palmitoyl-CoA hydrolase activity | Bos taurus | Apoptosis Cell membrane Cell projection Cytoplasm Fatty acid metabolism Hydrolase Lipid metabolism Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Transit peptide | MLRSCTAGLR | MLRSCTAGLRSIWALRGRREGAPRLSMDLQPARRLFSTEKVIHKDWALPNPSWSKDLKLLFDQFMKKCEDGSWERLPSYKRRSTQESEDFKTYFLDPKLVEEERLSQAQLFTRGFEDGLGFEYVIFKNNDEKRTVCLFQGGPYLQGVPGLLHGGAMATMIDIALGSCTGGAVMTANLNINFKRPVPLCSVVVINSQLDKLEGRKLFLSCNVRSVDEKTLYSEATGLFIKLDPEKSST | fatty acid metabolic process phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of mitochondrial membrane permeability involved in apoptotic process cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; ruffle membrane myristoyl-CoA hydrolase activity palmitoyl-CoA hydrolase activity Bos taurus Apoptosis Cell membrane Cell projection Cytoplasm Fatty acid metabolism Hydrolase Lipid metabolism Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Transit peptide MLRSCTAGLR MLRSCTAGLRSIWALRGRREGAPRLSMDLQPARRLFSTEKVIHKDWALPNPSWSKDLKLLFDQFMKKCEDGSWERLPSYKRRSTQESEDFKTYFLDPKLVEEERLSQAQLFTRGFEDGLGFEYVIFKNNDEKRTVCLFQGGPYLQGVPGLLHGGAMATMIDIALGSCTGGAVMTANLNINFKRPVPLCSVVVINSQLDKLEGRKLFLSCNVRSVDEKTLYSEATGLFIKLDPEKSST |
Mo-molybdopterin cofactor biosynthetic process protein urmylation tRNA thio-modification tRNA wobble position uridine thiolation tRNA wobble uridine modification | cytoplasm; cytosol | ATP binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity nucleotidyltransferase activity sulfurtransferase activity thiosulfate sulfurtransferase activity URM1 activating enzyme activity | Bos taurus | Alternative splicing ATP-binding Cytoplasm Disulfide bond Metal-binding Molybdenum cofactor biosynthesis Multifunctional enzyme Nucleotide-binding Reference proteome Transferase tRNA processing Zinc | MAAREEVLAL | MAAREEVLALQAEVAQREEELSSLKQRLAAALSTGQESARSVPVSPLPPRAALSREEIRRYSRQLVLPELGMQGQLRLAAAAVLVVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEASNLARQVLHGEALAGQAKVFSAAAALRRLNSAVECVPYAQALTPATALDLVRRYDVVADCSDNAPTRYLVSDACVLAGRPLVSASALRFEGQLTVYHYGGGPCYRCVFPRPPPAETVTSCADGGVLGAVTGVLGCLQALEVLKTAAGLGPSYSGRLLLFDALRGDFRCIRLRRRRPDCAACGERPTVTDLQDYESFCGSSATDKCRSLRLLSPEERISIMDYKRLLDSRSPHLLLDVRPQVEVDICRLPHALHIPLKSLERRDAESLKVLGEAIREGKQGAQEGASVPIYVICKLGNDSQKAVKILQSWADLDSLTVKDVVGGLMAWAAKIDGTFPQY | Mo-molybdopterin cofactor biosynthetic process protein urmylation tRNA thio-modification tRNA wobble position uridine thiolation tRNA wobble uridine modification cytoplasm; cytosol ATP binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity nucleotidyltransferase activity sulfurtransferase activity thiosulfate sulfurtransferase activity URM1 activating enzyme activity Bos taurus Alternative splicing ATP-binding Cytoplasm Disulfide bond Metal-binding Molybdenum cofactor biosynthesis Multifunctional enzyme Nucleotide-binding Reference proteome Transferase tRNA processing Zinc MAAREEVLAL MAAREEVLALQAEVAQREEELSSLKQRLAAALSTGQESARSVPVSPLPPRAALSREEIRRYSRQLVLPELGMQGQLRLAAAAVLVVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEASNLARQVLHGEALAGQAKVFSAAAALRRLNSAVECVPYAQALTPATALDLVRRYDVVADCSDNAPTRYLVSDACVLAGRPLVSASALRFEGQLTVYHYGGGPCYRCVFPRPPPAETVTSCADGGVLGAVTGVLGCLQALEVLKTAAGLGPSYSGRLLLFDALRGDFRCIRLRRRRPDCAACGERPTVTDLQDYESFCGSSATDKCRSLRLLSPEERISIMDYKRLLDSRSPHLLLDVRPQVEVDICRLPHALHIPLKSLERRDAESLKVLGEAIREGKQGAQEGASVPIYVICKLGNDSQKAVKILQSWADLDSLTVKDVVGGLMAWAAKIDGTFPQY |
adenosine transport cytidine transport dopamine transport guanine transmembrane transport inosine transport norepinephrine transport nucleobase transport nucleoside transmembrane transport nucleoside transport purine nucleobase transmembrane transport pyrimidine nucleobase transmembrane transport serotonin transport uracil transmembrane transport uridine transport | Golgi apparatus; late endosome membrane; lysosomal membrane; mitochondrial membrane; plasma membrane | cytidine transmembrane transporter activity guanine transmembrane transporter activity monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity nucleobase transmembrane transporter activity nucleoside transmembrane transporter activity organic cation transmembrane transporter activity uracil transmembrane transporter activity uridine transmembrane transporter activity | Bos taurus | Cell membrane Endosome Glycoprotein Lysosome Membrane Mitochondrion Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MAIISEDDFR | MAIISEDDFRHTSNSTYRTASSSLRADQEALLEKLLDRPPPSLQRPEDRFNGTYIIFFSLGIGGLLPWNFFVTAQEYWIFKLSNCSSPAAGEEPKDSDILNYFESYLAVASTVPSVLCLALNFLLVNRVPIRVRVLASLTVMLAIFIVMTVLVKVDTSSWTHSFFTITITCMAILSGTSTIFNSSVFGMTGSFPMRNSQALISGGAMGGTLSAVASLVDLAVASDVTDSTLAFFLTADIFLALCIGLYLLLPRLDYARYYMKPVWPTVFSGEEQLPQDSPSPTSVAPGSSDPQTPPLGPILKKTTGLGFCIIYLFFITSLIFPAICTNIESLSKGSGSPWSTKFFVPLTTFLLYNFADLCGRQVTAWIQVPGPRSKALPGLALLRTCFVPLFVFCNYQPRGHLHTVLFQSDVYPVLFTSLLGLSNGYLSTLALIYGPKIVPRELAEATGVVMTFYMGLGLVLGSACSALLVHLI | adenosine transport cytidine transport dopamine transport guanine transmembrane transport inosine transport norepinephrine transport nucleobase transport nucleoside transmembrane transport nucleoside transport purine nucleobase transmembrane transport pyrimidine nucleobase transmembrane transport serotonin transport uracil transmembrane transport uridine transport Golgi apparatus; late endosome membrane; lysosomal membrane; mitochondrial membrane; plasma membrane cytidine transmembrane transporter activity guanine transmembrane transporter activity monoamine transmembrane transporter activity neurotransmitter transmembrane transporter activity nucleobase transmembrane transporter activity nucleoside transmembrane transporter activity organic cation transmembrane transporter activity uracil transmembrane transporter activity uridine transmembrane transporter activity Bos taurus Cell membrane Endosome Glycoprotein Lysosome Membrane Mitochondrion Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport MAIISEDDFR MAIISEDDFRHTSNSTYRTASSSLRADQEALLEKLLDRPPPSLQRPEDRFNGTYIIFFSLGIGGLLPWNFFVTAQEYWIFKLSNCSSPAAGEEPKDSDILNYFESYLAVASTVPSVLCLALNFLLVNRVPIRVRVLASLTVMLAIFIVMTVLVKVDTSSWTHSFFTITITCMAILSGTSTIFNSSVFGMTGSFPMRNSQALISGGAMGGTLSAVASLVDLAVASDVTDSTLAFFLTADIFLALCIGLYLLLPRLDYARYYMKPVWPTVFSGEEQLPQDSPSPTSVAPGSSDPQTPPLGPILKKTTGLGFCIIYLFFITSLIFPAICTNIESLSKGSGSPWSTKFFVPLTTFLLYNFADLCGRQVTAWIQVPGPRSKALPGLALLRTCFVPLFVFCNYQPRGHLHTVLFQSDVYPVLFTSLLGLSNGYLSTLALIYGPKIVPRELAEATGVVMTFYMGLGLVLGSACSALLVHLI |
dITP catabolic process mRNA catabolic process NAD-cap decapping negative regulation of rRNA processing positive regulation of cell cycle process sno(s)RNA catabolic process | cytoplasm; nucleolus; nucleoplasm; nucleus | 5'-(N(7)-methylguanosine 5'-triphospho)- hydrolase activity chloride ion binding cobalt ion binding dIDP phosphatase activity dITP diphosphatase activity IDP phosphatase activity magnesium ion binding manganese ion binding metalloexopeptidase activity mRNA binding nucleotide binding phosphodiesterase decapping endonuclease activity protein homodimerization activity RNA NAD-cap (NAD-forming) hydrolase activity snoRNA binding | Bos taurus | Cytoplasm Hydrolase Magnesium Manganese Metal-binding Nucleotide metabolism Nucleotide-binding Nucleus Reference proteome RNA-binding | MAGMRRLELS | MAGMRRLELSEALHLGPGWRHACHALLYAPDPGLLFGRIPLRYAVLMQMRFDGRLGFPGGFVDLRDGSLEDGLNRELGEELGEAAGAFRVERADYRSSHAGSRPRVVAHFYTKLLTLEQLTAVEMGAPRARDHGLEVLGLVRVPLYTLRDGVGGLPAFLENTFIGNAREQLLEAVQNLGLLEPGSFARLKISTPP | dITP catabolic process mRNA catabolic process NAD-cap decapping negative regulation of rRNA processing positive regulation of cell cycle process sno(s)RNA catabolic process cytoplasm; nucleolus; nucleoplasm; nucleus 5'-(N(7)-methylguanosine 5'-triphospho)- hydrolase activity chloride ion binding cobalt ion binding dIDP phosphatase activity dITP diphosphatase activity IDP phosphatase activity magnesium ion binding manganese ion binding metalloexopeptidase activity mRNA binding nucleotide binding phosphodiesterase decapping endonuclease activity protein homodimerization activity RNA NAD-cap (NAD-forming) hydrolase activity snoRNA binding Bos taurus Cytoplasm Hydrolase Magnesium Manganese Metal-binding Nucleotide metabolism Nucleotide-binding Nucleus Reference proteome RNA-binding MAGMRRLELS MAGMRRLELSEALHLGPGWRHACHALLYAPDPGLLFGRIPLRYAVLMQMRFDGRLGFPGGFVDLRDGSLEDGLNRELGEELGEAAGAFRVERADYRSSHAGSRPRVVAHFYTKLLTLEQLTAVEMGAPRARDHGLEVLGLVRVPLYTLRDGVGGLPAFLENTFIGNAREQLLEAVQNLGLLEPGSFARLKISTPP |
anatomical structure development bone morphogenesis cellular response to iron ion embryonic cranial skeleton morphogenesis embryonic forelimb morphogenesis eyelid development in camera-type eye inner ear morphogenesis kidney development negative regulation of apoptotic process negative regulation of reactive oxygen species metabolic process negative regulation of transcription by competitive promoter binding negative regulation of transcription by RNA polymerase II oculomotor nerve formation optic cup structural organization optic vesicle morphogenesis positive regulation of bone mineralization positive regulation of tooth mineralization positive regulation of transcription by RNA polymerase II regulation of cell population proliferation regulation of transcription by RNA polymerase II roof of mouth development sensory perception of sound trigeminal nerve development | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Bos taurus | Activator DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MLWKLTDNIK | MLWKLTDNIKYEDCEDRHDGASNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHGLGSGLGDLPIHSLPHAIEDVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK | anatomical structure development bone morphogenesis cellular response to iron ion embryonic cranial skeleton morphogenesis embryonic forelimb morphogenesis eyelid development in camera-type eye inner ear morphogenesis kidney development negative regulation of apoptotic process negative regulation of reactive oxygen species metabolic process negative regulation of transcription by competitive promoter binding negative regulation of transcription by RNA polymerase II oculomotor nerve formation optic cup structural organization optic vesicle morphogenesis positive regulation of bone mineralization positive regulation of tooth mineralization positive regulation of transcription by RNA polymerase II regulation of cell population proliferation regulation of transcription by RNA polymerase II roof of mouth development sensory perception of sound trigeminal nerve development nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding Bos taurus Activator DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation MLWKLTDNIK MLWKLTDNIKYEDCEDRHDGASNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHGLGSGLGDLPIHSLPHAIEDVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK |
cytoskeleton organization negative regulation of apoptotic process regulation of small GTPase mediated signal transduction signal transduction | cytosol; endosome membrane; perinuclear region of cytoplasm; plasma membrane | GTPase activator activity | Homo sapiens | 3D-structure Cell membrane Cytoplasm Endosome GTPase activation Membrane Phosphoprotein Reference proteome SH3 domain | MGLQPLEFSD | MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKFAHSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKFNMIPFEHRSGGKLGDGEVFFLKECTKRHTDSIDRRFCFDIEAADRPGVSLTMQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGPPGPDKNHLLADGGSFGDWASTIPGQTRSSMVQWLNPQSPTTTSSNSAVTPLSPGSSPFPFSPPATVADKPPESIRSRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL | cytoskeleton organization negative regulation of apoptotic process regulation of small GTPase mediated signal transduction signal transduction cytosol; endosome membrane; perinuclear region of cytoplasm; plasma membrane GTPase activator activity Homo sapiens 3D-structure Cell membrane Cytoplasm Endosome GTPase activation Membrane Phosphoprotein Reference proteome SH3 domain MGLQPLEFSD MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKFAHSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKFNMIPFEHRSGGKLGDGEVFFLKECTKRHTDSIDRRFCFDIEAADRPGVSLTMQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGPPGPDKNHLLADGGSFGDWASTIPGQTRSSMVQWLNPQSPTTTSSNSAVTPLSPGSSPFPFSPPATVADKPPESIRSRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL |
fertilization positive regulation of DNA-templated transcription transcription by RNA polymerase II | nucleus | DNA binding metal ion binding | Homo sapiens | Activator Alternative splicing DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MKRRQKRKHL | MKRRQKRKHLENEESQETAEKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSCVSSSRKLIHSGIQRIHRDSPQPQSPLAQVQERGETPPRSQHVSLSSYSSYKTCVSSLCVNKEERGMKIYYMQVQMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRNLLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTMEALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRSWSQCPGCVFHSPKDRNS | fertilization positive regulation of DNA-templated transcription transcription by RNA polymerase II nucleus DNA binding metal ion binding Homo sapiens Activator Alternative splicing DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Zinc Zinc-finger MKRRQKRKHL MKRRQKRKHLENEESQETAEKGGGMSKSQEDALQPGSTRVAKGWSQGVGEVTSTSEYCSCVSSSRKLIHSGIQRIHRDSPQPQSPLAQVQERGETPPRSQHVSLSSYSSYKTCVSSLCVNKEERGMKIYYMQVQMNKGVAVSWETEETLESLEKQPRMEEVTLSEVVRVGTPPSDVSTRNLLSDSEPSGEEKEHEERTESDSLPGSPTVEDTPRAKTPDWLVTMENGFRCMACCRVFTTMEALQEHVQFGIREGFSCHVFHLTMAQLTGNMESESTQDEQEEENGNEKEEEEKPEAKEEEGQPTEEDLGLRRSWSQCPGCVFHSPKDRNS |
negative regulation of intestinal absorption regulation of transcription by RNA polymerase II regulation of vitamin A metabolic process | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Activator Alternative splicing DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MAGPTIHRDM | MAGPTIHRDMEKSSGYCEAPENLGLSFSIEAILKKPTERRSLPRPQSICKEDSRQTTIPGSKLERPPQDQPQEEKKNKRRVRTTFTTEQLQELEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEKSGNLSAPQQPGEAGLALPSNMDVSGPVLTPTAMTTLVPPTECCLLSQTQLPSSWFPTQIPLVPWHPWDLQPLPGPLTQHPCVPTFMFPPLHPKWGSICATST | negative regulation of intestinal absorption regulation of transcription by RNA polymerase II regulation of vitamin A metabolic process nucleus DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus Activator Alternative splicing DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation MAGPTIHRDM MAGPTIHRDMEKSSGYCEAPENLGLSFSIEAILKKPTERRSLPRPQSICKEDSRQTTIPGSKLERPPQDQPQEEKKNKRRVRTTFTTEQLQELEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEKSGNLSAPQQPGEAGLALPSNMDVSGPVLTPTAMTTLVPPTECCLLSQTQLPSSWFPTQIPLVPWHPWDLQPLPGPLTQHPCVPTFMFPPLHPKWGSICATST |
antimicrobial humoral immune response mediated by antimicrobial peptide biological process involved in interaction with host defense response to Gram-positive bacterium detection of bacterium innate immune response killing of cells of another organism negative regulation of natural killer cell differentiation involved in immune response negative regulation of type II interferon production peptidoglycan catabolic process | extracellular region; protein-containing complex | N-acetylmuramoyl-L-alanine amidase activity peptidoglycan binding peptidoglycan immune receptor activity protein heterodimerization activity zinc ion binding | Mus musculus | Antibiotic Antimicrobial Disulfide bond Glycoprotein Immunity Innate immunity Reference proteome Repeat Secreted Signal | MLVSWDHPKM | MLVSWDHPKMLPRLLGFLALSLLACGNPTIVSRKEWGASSLTCRVPLSLPVPYLIIEQVTRMQCQDQITCSQVVRVLQSQYVHNKGWCDIAFNFLVGDDGKVYEGVGWYVQGLHTQGYNNVSLGIAFFGSKIGSPSPAALSATEDLIFFAIQNGYLSPKYIQPFLLKEETCLVPQHSEIPKKACPNITPRSAWEARETHCPQMNLPAKFVIIIHTAGKSCNESADCLVRVRDTQSFHIDNQDFCDIAYHFLVGQDGEVYEGVGWNIEGSHTYGYNDIALGIAFMGNFVEKPPNEASLKAAQSLIQCAVAKGYLTSNYLLMGHSDVSNILSPGQALYNIIKTWPHFKH | antimicrobial humoral immune response mediated by antimicrobial peptide biological process involved in interaction with host defense response to Gram-positive bacterium detection of bacterium innate immune response killing of cells of another organism negative regulation of natural killer cell differentiation involved in immune response negative regulation of type II interferon production peptidoglycan catabolic process extracellular region; protein-containing complex N-acetylmuramoyl-L-alanine amidase activity peptidoglycan binding peptidoglycan immune receptor activity protein heterodimerization activity zinc ion binding Mus musculus Antibiotic Antimicrobial Disulfide bond Glycoprotein Immunity Innate immunity Reference proteome Repeat Secreted Signal MLVSWDHPKM MLVSWDHPKMLPRLLGFLALSLLACGNPTIVSRKEWGASSLTCRVPLSLPVPYLIIEQVTRMQCQDQITCSQVVRVLQSQYVHNKGWCDIAFNFLVGDDGKVYEGVGWYVQGLHTQGYNNVSLGIAFFGSKIGSPSPAALSATEDLIFFAIQNGYLSPKYIQPFLLKEETCLVPQHSEIPKKACPNITPRSAWEARETHCPQMNLPAKFVIIIHTAGKSCNESADCLVRVRDTQSFHIDNQDFCDIAYHFLVGQDGEVYEGVGWNIEGSHTYGYNDIALGIAFMGNFVEKPPNEASLKAAQSLIQCAVAKGYLTSNYLLMGHSDVSNILSPGQALYNIIKTWPHFKH |
calcium activated galactosylceramide scrambling calcium activated phosphatidylcholine scrambling calcium activated phosphatidylserine scrambling chloride transmembrane transport chloride transport establishment of localization in cell lipid metabolic process monoatomic ion transmembrane transport negative regulation of intracellular calcium activated chloride channel activity | plasma membrane | chloride channel activity intracellular calcium activated chloride channel activity phospholipid scramblase activity | Homo sapiens | Alternative splicing Cell membrane Glycoprotein Lipid metabolism Lipid transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MQGEESLRIL | MQGEESLRILVEPEGDSFPLMEISTCETEASEQWDYVLVAQRHTQRDPRQARQQQFLEELRRKGFHIKVIRDQKQVFFGIRADNSVFGLYRTLLLEPEGPAPHAELAAPTTIPVTTSLRIRIVNFVVMNNKTSAGETFEDLMKDGVFEARFPLHKGEGRLKKTWARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYVWDEEQEEMALQLINCPDYKLRPYQHSYLRSTVILVLTLLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLPRDPELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQRLGGVGAGSRPPMPAHPTPASIFSARSTDV | calcium activated galactosylceramide scrambling calcium activated phosphatidylcholine scrambling calcium activated phosphatidylserine scrambling chloride transmembrane transport chloride transport establishment of localization in cell lipid metabolic process monoatomic ion transmembrane transport negative regulation of intracellular calcium activated chloride channel activity plasma membrane chloride channel activity intracellular calcium activated chloride channel activity phospholipid scramblase activity Homo sapiens Alternative splicing Cell membrane Glycoprotein Lipid metabolism Lipid transport Membrane Reference proteome Transmembrane Transmembrane helix Transport MQGEESLRIL MQGEESLRILVEPEGDSFPLMEISTCETEASEQWDYVLVAQRHTQRDPRQARQQQFLEELRRKGFHIKVIRDQKQVFFGIRADNSVFGLYRTLLLEPEGPAPHAELAAPTTIPVTTSLRIRIVNFVVMNNKTSAGETFEDLMKDGVFEARFPLHKGEGRLKKTWARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYVWDEEQEEMALQLINCPDYKLRPYQHSYLRSTVILVLTLLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLPRDPELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQRLGGVGAGSRPPMPAHPTPASIFSARSTDV |
monoatomic ion transport | plasma membrane | transmembrane transporter activity | Homo sapiens | Alternative splicing Glycoprotein Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MAIDRRREAA | MAIDRRREAAGGGPGRQPAPAEENGSLPPGDAAASAPLGGRAGPGGGAEIQPLPPLHPGGGPHPSCCSAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGGDTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM | monoatomic ion transport plasma membrane transmembrane transporter activity Homo sapiens Alternative splicing Glycoprotein Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport MAIDRRREAA MAIDRRREAAGGGPGRQPAPAEENGSLPPGDAAASAPLGGRAGPGGGAEIQPLPPLHPGGGPHPSCCSAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGGDTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPHKKGEQPLLLTNAELKDYSGLHDAAAAGDTLPEGATANGMKAM |
adherens junction maintenance cell differentiation convergent extension involved in gastrulation innate immune response phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway | centrosome; cytosol; extrinsic component of cytoplasmic side of plasma membrane | ATP binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity signaling receptor binding | Danio rerio | ATP-binding Cell membrane Cytoplasm Cytoskeleton Developmental protein Kinase Lipoprotein Membrane Myristate Nucleotide-binding Palmitate Phosphoprotein Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase | MGCVKSKEDK | MGCVKSKEDKGPTQKYRPDPTNPTPGSHMGLYGPDPTQMGQSPALKGPTNNYNSRSSGLTPFGGSSSVITPFGGASSSFSTVAVNNPFPGVVTGGVTFFVALYDYEARTSDDLSFSKGDRFQIINNTEGDWWEARSINTGQKGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLLPGNQRGTFLVRESETTKGAYSLSIRDWDEMKGDNVKHYKIRKLDSGGYYITTRAQFDTLQKLVKHYTEHADGLCYRLTTVCPTVKPQTQGLAKDAWEIPRESLRLELKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEYIQSFLEDYFTATEPQYQPGDNL | adherens junction maintenance cell differentiation convergent extension involved in gastrulation innate immune response phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway centrosome; cytosol; extrinsic component of cytoplasmic side of plasma membrane ATP binding non-membrane spanning protein tyrosine kinase activity protein tyrosine kinase activity signaling receptor binding Danio rerio ATP-binding Cell membrane Cytoplasm Cytoskeleton Developmental protein Kinase Lipoprotein Membrane Myristate Nucleotide-binding Palmitate Phosphoprotein Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase MGCVKSKEDK MGCVKSKEDKGPTQKYRPDPTNPTPGSHMGLYGPDPTQMGQSPALKGPTNNYNSRSSGLTPFGGSSSVITPFGGASSSFSTVAVNNPFPGVVTGGVTFFVALYDYEARTSDDLSFSKGDRFQIINNTEGDWWEARSINTGQKGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLLPGNQRGTFLVRESETTKGAYSLSIRDWDEMKGDNVKHYKIRKLDSGGYYITTRAQFDTLQKLVKHYTEHADGLCYRLTTVCPTVKPQTQGLAKDAWEIPRESLRLELKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEYIQSFLEDYFTATEPQYQPGDNL |
actin filament organization actin filament polymerization actin nucleation muscle contraction myofibril assembly pointed-end actin filament capping positive regulation of actin filament polymerization sarcomere organization | actin filament; cardiac myofibril; cytoskeleton; M band; myofibril; sarcomere; striated muscle thin filament | actin binding actin monomer binding tropomyosin binding | Rattus norvegicus | Actin-binding Coiled coil Cytoplasm Cytoskeleton Phosphoprotein Reference proteome | MSTFGYRRGL | MSTFGYRRGLSKYESIDEDELLASLTAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGNFSREALMAYWEKESQKLLEKERLGECGKLAEEDKEESEEELIFTESNSEVSEEVCTEEEEESTEEEEEEEEEDSEEEEVTTEVTKHINGTVSHNGVNPDNSKPKTFKSQIENINLTNGNSGGTQRNTESPAAIHPCGNPTVIEDALEKIKNNDPDTTEVNLNNIENITTQTLSRFAEALKENTVVKTFSLANTHADDAAAIAIAEMLKVNEHITSVNVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRMQEQKQQEGHDGGATLRTKVWQRGTPGSSPYASPRQSPWSSPKVSKKVHTGRSRPPSPVAPPPPPPPPPLPPHMLPPPPPPPAPPLPGKKLITRNIAEVIKQQESAQRALQNGQRKKKGKKVKKQPNNILKEIKNSLRSVQEKKMEESSRPSTPQRSAHENLMEAIRGSSIRQLRRVEVPEALR | actin filament organization actin filament polymerization actin nucleation muscle contraction myofibril assembly pointed-end actin filament capping positive regulation of actin filament polymerization sarcomere organization actin filament; cardiac myofibril; cytoskeleton; M band; myofibril; sarcomere; striated muscle thin filament actin binding actin monomer binding tropomyosin binding Rattus norvegicus Actin-binding Coiled coil Cytoplasm Cytoskeleton Phosphoprotein Reference proteome MSTFGYRRGL MSTFGYRRGLSKYESIDEDELLASLTAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGNFSREALMAYWEKESQKLLEKERLGECGKLAEEDKEESEEELIFTESNSEVSEEVCTEEEEESTEEEEEEEEEDSEEEEVTTEVTKHINGTVSHNGVNPDNSKPKTFKSQIENINLTNGNSGGTQRNTESPAAIHPCGNPTVIEDALEKIKNNDPDTTEVNLNNIENITTQTLSRFAEALKENTVVKTFSLANTHADDAAAIAIAEMLKVNEHITSVNVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRMQEQKQQEGHDGGATLRTKVWQRGTPGSSPYASPRQSPWSSPKVSKKVHTGRSRPPSPVAPPPPPPPPPLPPHMLPPPPPPPAPPLPGKKLITRNIAEVIKQQESAQRALQNGQRKKKGKKVKKQPNNILKEIKNSLRSVQEKKMEESSRPSTPQRSAHENLMEAIRGSSIRQLRRVEVPEALR |
cellular response to ionizing radiation chromatin remodeling DNA damage response double-strand break repair via homologous recombination inflammatory response positive regulation of double-strand break repair via nonhomologous end joining regulation of gene expression regulation of protein phosphorylation | chromatin; nucleus; pericentric heterochromatin; site of double-strand break | chromatin DNA binding damaged DNA binding histone demethylase activity histone H3K9 demethylase activity histone H3K9me2/H3K9me3 demethylase activity metal ion binding | Rattus norvegicus | ADP-ribosylation Chromatin regulator Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Reference proteome Transcription Transcription regulation Ubl conjugation Zinc | MKTKSTCAQN | MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRARQSYDNISNILIATPLQQVVSGQAGVFTQYHKKKKAMTVGQYRHLANSKKYQTPPHLDFEDLERKYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLELLAKELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYEMWKRGQDQAVVDHTEAMGPTSQELTTWRVIQAPRKTWGLKHLRLRQVSRCLLPVATDSNIANNTQMCHTSRQAADSKGDEVQESDPAIAPPYPLGLSSPGHMSTGKRGLGRRPCELGVQESTNGAPVKRRLPEGRDDRSPSPELQSQSVTGDLIVNSDLVNPGPQHPVTASEGGLTSDP | cellular response to ionizing radiation chromatin remodeling DNA damage response double-strand break repair via homologous recombination inflammatory response positive regulation of double-strand break repair via nonhomologous end joining regulation of gene expression regulation of protein phosphorylation chromatin; nucleus; pericentric heterochromatin; site of double-strand break chromatin DNA binding damaged DNA binding histone demethylase activity histone H3K9 demethylase activity histone H3K9me2/H3K9me3 demethylase activity metal ion binding Rattus norvegicus ADP-ribosylation Chromatin regulator Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Reference proteome Transcription Transcription regulation Ubl conjugation Zinc MKTKSTCAQN MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRARQSYDNISNILIATPLQQVVSGQAGVFTQYHKKKKAMTVGQYRHLANSKKYQTPPHLDFEDLERKYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLELLAKELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYEMWKRGQDQAVVDHTEAMGPTSQELTTWRVIQAPRKTWGLKHLRLRQVSRCLLPVATDSNIANNTQMCHTSRQAADSKGDEVQESDPAIAPPYPLGLSSPGHMSTGKRGLGRRPCELGVQESTNGAPVKRRLPEGRDDRSPSPELQSQSVTGDLIVNSDLVNPGPQHPVTASEGGLTSDP |
cellular response to angiotensin cellular response to endothelin cellular response to hydrogen peroxide cellular response to retinoic acid dendrite morphogenesis heart development intracellular estrogen receptor signaling pathway mRNA alternative polyadenylation negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of membrane hyperpolarization negative regulation of mitochondrial depolarization nervous system development neuromuscular process controlling balance positive regulation of gene expression positive regulation of vasoconstriction radial glia guided migration of Purkinje cell regulation of alternative mRNA splicing, via spliceosome regulation of definitive erythrocyte differentiation regulation of mitochondrial gene expression RNA splicing | cytoplasm; nucleus | DNA-binding transcription factor binding mRNA binding RNA binding single-stranded RNA binding transcription corepressor activity | Rattus norvegicus | Cytoplasm Methylation mRNA processing mRNA splicing Nucleus Reference proteome RNA-binding | MAEGGQAQQQ | MAEGGQAQQQPPQLGPGAAARGMKRESEVELPVPGAGADGPEPGLSKRPRTEEAADEGMQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTSEHNLTLYGSSQPHGEQSSNSPSNQNGSLTQTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAASSFQADVSLGNEAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPATATAATAAAAAAAAYSDGYGRVYTADPYHALAPAASYGVGAVASLYRGGYSRFAPY | cellular response to angiotensin cellular response to endothelin cellular response to hydrogen peroxide cellular response to retinoic acid dendrite morphogenesis heart development intracellular estrogen receptor signaling pathway mRNA alternative polyadenylation negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of membrane hyperpolarization negative regulation of mitochondrial depolarization nervous system development neuromuscular process controlling balance positive regulation of gene expression positive regulation of vasoconstriction radial glia guided migration of Purkinje cell regulation of alternative mRNA splicing, via spliceosome regulation of definitive erythrocyte differentiation regulation of mitochondrial gene expression RNA splicing cytoplasm; nucleus DNA-binding transcription factor binding mRNA binding RNA binding single-stranded RNA binding transcription corepressor activity Rattus norvegicus Cytoplasm Methylation mRNA processing mRNA splicing Nucleus Reference proteome RNA-binding MAEGGQAQQQ MAEGGQAQQQPPQLGPGAAARGMKRESEVELPVPGAGADGPEPGLSKRPRTEEAADEGMQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTSEHNLTLYGSSQPHGEQSSNSPSNQNGSLTQTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAASSFQADVSLGNEAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPATATAATAAAAAAAAYSDGYGRVYTADPYHALAPAASYGVGAVASLYRGGYSRFAPY |
cellular response to abscisic acid stimulus cellular response to cold cellular response to phosphate starvation cellular response to sucrose stimulus cytokinin-activated signaling pathway defense response to bacterium leaf senescence negative regulation of iron ion transport phloem or xylem histogenesis regulation of chlorophyll catabolic process regulation of flower development regulation of meristem development regulation of seed germination response to salt stress response to water deprivation secondary growth | plasma membrane | phosphorelay sensor kinase activity protein histidine kinase binding | Oryza sativa subsp. japonica | Cell membrane Cytokinin signaling pathway Kinase Membrane Phosphoprotein Reference proteome Repeat Transferase Transmembrane Transmembrane helix Two-component regulatory system | MDEMSCGGGG | MDEMSCGGGGGGARWKRARVAGMGEGKAGGGGGAAFLGLERVGMVVRMLPVPEKVSARARVVRGSLVAHFRGWRVVRETWWWVLLLWILAGSLGSFYLFLFMNAQSLDKRRDSLASMCDERARMLQDQFNVSMNHLQALAILVSTFHHSKTPSAIDQMTFARYAERTAFERPLTSGVAYAVRVTHGEREQFERQQGWAIKKMYSSSNKKQSSPGPGPGDAAVAEIREPAEEYAPVIFAQDAYKHVISFDMLSGNEDRDNILRARKSGKGVLTAPFKLLNNRLGVILTYTVYKYELPAYARPHERIQAAIGYLGGIFDIQALVEKLLKQLASQESIMVNVYDTTNESPISMYGDDTGSGMCHVSVLNFGDPSRKHEMHCRFEKKPPWPWLAITSSFGTLVIALLTGHIFQATVHRIAKVEDDFHKMSELKKRAEDADVAKSQFLATVSHEIRTPMNGVLGMLQMLMDTDLDTTQQDYVRTAQASGKALVSLINEVLDQAKIESGKLELETVPFDLRTVCDDILSLFCGKAQEKGLELAVYVSDQVPQILIGDPGRIRQIITNLVGNSIKFTERGHIYLTVHVVEEVMSCLEVETGIQNTNTLSGYPVANRRCSWESIRLFNRELHSSEKSFAPIASDSISLVISVEDTGVGIPFEAQSRVFTPFMQVGPSIARIHGGTGIGLSISKCLVGLMKGEIGFASKPHVGSTFTFTAVLMRAHCKGNDIKSSEFKGINALVVDHRPVRAKVTKYHLQRLGVKTELTAELNQFISKLNSGSLTAKLVLIDKETWLKESHCTPLLVNKLRNNDKPDSPKLFLLGSSASSPKGGSDTSREHNLNVIMKPLRASMLQVSLRRALGGVDKVHCRNGVVGNSTLGSLLHKKQIIVVDDNIVNLKVAAGALKKYGAEVTCADSGKKAITLLKPPHNFDACFMDIQMPEMDGFEATRRIRVMERDLNERIERGEAPPECASIQRWRTPILAMTADVIQATHEECLKSEMDGYVSKPFEGEQLYSEVARFFQNHDQVE | cellular response to abscisic acid stimulus cellular response to cold cellular response to phosphate starvation cellular response to sucrose stimulus cytokinin-activated signaling pathway defense response to bacterium leaf senescence negative regulation of iron ion transport phloem or xylem histogenesis regulation of chlorophyll catabolic process regulation of flower development regulation of meristem development regulation of seed germination response to salt stress response to water deprivation secondary growth plasma membrane phosphorelay sensor kinase activity protein histidine kinase binding Oryza sativa subsp. japonica Cell membrane Cytokinin signaling pathway Kinase Membrane Phosphoprotein Reference proteome Repeat Transferase Transmembrane Transmembrane helix Two-component regulatory system MDEMSCGGGG MDEMSCGGGGGGARWKRARVAGMGEGKAGGGGGAAFLGLERVGMVVRMLPVPEKVSARARVVRGSLVAHFRGWRVVRETWWWVLLLWILAGSLGSFYLFLFMNAQSLDKRRDSLASMCDERARMLQDQFNVSMNHLQALAILVSTFHHSKTPSAIDQMTFARYAERTAFERPLTSGVAYAVRVTHGEREQFERQQGWAIKKMYSSSNKKQSSPGPGPGDAAVAEIREPAEEYAPVIFAQDAYKHVISFDMLSGNEDRDNILRARKSGKGVLTAPFKLLNNRLGVILTYTVYKYELPAYARPHERIQAAIGYLGGIFDIQALVEKLLKQLASQESIMVNVYDTTNESPISMYGDDTGSGMCHVSVLNFGDPSRKHEMHCRFEKKPPWPWLAITSSFGTLVIALLTGHIFQATVHRIAKVEDDFHKMSELKKRAEDADVAKSQFLATVSHEIRTPMNGVLGMLQMLMDTDLDTTQQDYVRTAQASGKALVSLINEVLDQAKIESGKLELETVPFDLRTVCDDILSLFCGKAQEKGLELAVYVSDQVPQILIGDPGRIRQIITNLVGNSIKFTERGHIYLTVHVVEEVMSCLEVETGIQNTNTLSGYPVANRRCSWESIRLFNRELHSSEKSFAPIASDSISLVISVEDTGVGIPFEAQSRVFTPFMQVGPSIARIHGGTGIGLSISKCLVGLMKGEIGFASKPHVGSTFTFTAVLMRAHCKGNDIKSSEFKGINALVVDHRPVRAKVTKYHLQRLGVKTELTAELNQFISKLNSGSLTAKLVLIDKETWLKESHCTPLLVNKLRNNDKPDSPKLFLLGSSASSPKGGSDTSREHNLNVIMKPLRASMLQVSLRRALGGVDKVHCRNGVVGNSTLGSLLHKKQIIVVDDNIVNLKVAAGALKKYGAEVTCADSGKKAITLLKPPHNFDACFMDIQMPEMDGFEATRRIRVMERDLNERIERGEAPPECASIQRWRTPILAMTADVIQATHEECLKSEMDGYVSKPFEGEQLYSEVARFFQNHDQVE |
cytokinin-activated signaling pathway protein phosphorylation | plasma membrane | cytokine binding phosphorelay sensor kinase activity protein histidine kinase activity | Oryza sativa subsp. japonica | Cell membrane Cytokinin signaling pathway Kinase Membrane Phosphoprotein Reference proteome Repeat Transferase Transmembrane Transmembrane helix Two-component regulatory system | MGVGGGGGGG | MGVGGGGGGGGGEAAAAVAVEGDEAGKGRRWWRVKVKLSTVAVVAWVLASAALWAGLHWRFRRAALHKAEEALVCMCEERARMLQDQFAVSVNHVHALAILVATFHYDKHPPALDQDTFAVYAARTSFERPLLSGVAYAQRVVHADRESFERQQGWIIKTMKHEPSPAQDEYAPVIYSQETISYIEGLDVMSGEEDRENILRARATGKAVLTRPFRLMSNHLGVVLTFPVYLVDLPNDTAVEDRVAATAGYLGGAFDVESLVENLLRQLAGNQELVVNVYDVTNHSNPLVMYGSEVPLGIPSPSHTYTLDFGDPLRKHQMVCRYRNKLHVSWSAITTPSGVFVICMLVGYIIYAAWSRYDNVKEDCRKMEALKKRAEAADIAKSQFLATVSHEIRTPMNGVLGMLDMLLDTELKSTQRDYAQTAQVCGKALISLINEVLDRAKIEAGKIDLESVPFDLRSILDDVISLFSSKSREKGIELAVYVSERVPEILLGDPGRFRQIITNLVGNSIKFTERGHIFVQVHLADHSNLATEAKIEPVVNGMNGHKDEAIAIPTSGSHNTLSGFEAADSRNNWENFKLLLSYEKNEMPYESDSDKVTLVVSVEDTGIGIPLHAQGRVFTPFMQADSSTSRNYGGTGIGLSISKCLVEIMGGQINFVSRPLVGSTFTFTAVLRRCDKNAISDSKTVALHPLPSSFKGLSALLVDKRPVRATVTKYHLQRLGITSEVVGTIDPTFGVLSGRNGSSLTSIGKKQPCMLLIESDSWGPQMDVSLHARLQEMKQSDRIHVLPKVFLLSAAESDKVKKIHAVDSVIPKPLKASALAACLFQALGITQPSHEKRDDSGSLHGRDGSGSLHGLLLGKNILVVDDNKVNLRVAAGTLKKYGAKVECVESGKDALSLLQVPHKFDLCLMDIQMPEMDGFEATRQIRAMEGKANEQADDSESGSEIAAKTAKWHLPILAMTADVIQATHEECTKCGMDGYVSKPFEEKQLFQAVQKFLGPCVSS | cytokinin-activated signaling pathway protein phosphorylation plasma membrane cytokine binding phosphorelay sensor kinase activity protein histidine kinase activity Oryza sativa subsp. japonica Cell membrane Cytokinin signaling pathway Kinase Membrane Phosphoprotein Reference proteome Repeat Transferase Transmembrane Transmembrane helix Two-component regulatory system MGVGGGGGGG MGVGGGGGGGGGEAAAAVAVEGDEAGKGRRWWRVKVKLSTVAVVAWVLASAALWAGLHWRFRRAALHKAEEALVCMCEERARMLQDQFAVSVNHVHALAILVATFHYDKHPPALDQDTFAVYAARTSFERPLLSGVAYAQRVVHADRESFERQQGWIIKTMKHEPSPAQDEYAPVIYSQETISYIEGLDVMSGEEDRENILRARATGKAVLTRPFRLMSNHLGVVLTFPVYLVDLPNDTAVEDRVAATAGYLGGAFDVESLVENLLRQLAGNQELVVNVYDVTNHSNPLVMYGSEVPLGIPSPSHTYTLDFGDPLRKHQMVCRYRNKLHVSWSAITTPSGVFVICMLVGYIIYAAWSRYDNVKEDCRKMEALKKRAEAADIAKSQFLATVSHEIRTPMNGVLGMLDMLLDTELKSTQRDYAQTAQVCGKALISLINEVLDRAKIEAGKIDLESVPFDLRSILDDVISLFSSKSREKGIELAVYVSERVPEILLGDPGRFRQIITNLVGNSIKFTERGHIFVQVHLADHSNLATEAKIEPVVNGMNGHKDEAIAIPTSGSHNTLSGFEAADSRNNWENFKLLLSYEKNEMPYESDSDKVTLVVSVEDTGIGIPLHAQGRVFTPFMQADSSTSRNYGGTGIGLSISKCLVEIMGGQINFVSRPLVGSTFTFTAVLRRCDKNAISDSKTVALHPLPSSFKGLSALLVDKRPVRATVTKYHLQRLGITSEVVGTIDPTFGVLSGRNGSSLTSIGKKQPCMLLIESDSWGPQMDVSLHARLQEMKQSDRIHVLPKVFLLSAAESDKVKKIHAVDSVIPKPLKASALAACLFQALGITQPSHEKRDDSGSLHGRDGSGSLHGLLLGKNILVVDDNKVNLRVAAGTLKKYGAKVECVESGKDALSLLQVPHKFDLCLMDIQMPEMDGFEATRQIRAMEGKANEQADDSESGSEIAAKTAKWHLPILAMTADVIQATHEECTKCGMDGYVSKPFEEKQLFQAVQKFLGPCVSS |
cytokinin-activated signaling pathway protein phosphorylation | plasma membrane | cytokine binding phosphorelay sensor kinase activity protein histidine kinase activity | Oryza sativa subsp. japonica | Cell membrane Cytokinin signaling pathway Kinase Membrane Phosphoprotein Reference proteome Repeat Transferase Transmembrane Transmembrane helix Two-component regulatory system | MGKPEARSGW | MGKPEARSGWRNAAAAAWVLVAVACAAYMHWHLRRETMDRAEERLVSMCEERARMLQEQFGVTVNHVHALAILISTFHFEKFPSAIDQDTFAKYTARTSFERPLLNGVAYAQRIFHHEREMFENQQGWIMKTMKRQAAPPQDEYAPVIFSQDTVSYLARIDMMSGEEDRENILRARATGKAVLTNPFRLLGSNHLGVVLTFAVYRPGLAADASVEERVEATAGYLGGAFDVESLVENLLSKLAGNQDIVVNVYDVTNASEPMAMYGPQSPDGKVSLFHVSTLDFGDPFRAHEMRCRYRQKPPLPWSAITNPLGTFVIWMLVGYIICAAWSRYDKVSEDCRKMEELKTQAEAADVAKSQFLATVSHEIRTPMNGVLGMLDMLLGTDLSMTQKDYAQTAQMCGRALITLINDVLDRAKIEAGKLELEAVPFDLRSLMDDVISLFSSKSREKCIELAVFVCDDVPKVVIGDPWRYRQILTNLVGNAVKFTERGHVFVRVCLAENSKVEANQVLNGTMNGKDGKVETTANGAFNTLSGFQAADERNNWDYFKLLLSDKEPHMDELECDRSYQNDCDCVTLMISIEDTGVGIPLHAQDRVFTPFMQADSSTSRNYGGTGIGLSISKCLAELMGGQISFTSRPFVGSTFTFSAVLKRSCKDTSSDSKRSLSEALPTAFKGMKAILVDGRPVRGAVTRYHLNRLGIVVKVVNNLSMGLQTLAGQNGVKESREKLSMLFIESDIWRPETDILLLNRLHELKNNGQVHELPKLVLLVTSEADKDRYGSAFDIVMYKPIRASTIASCLQQLLKVVMPERKDNQNRPSFLRSLLIGKNILIVDDNKVNLRVAAAALKKYGAKVHCVESGKDAVSLLQQPHCFDACFMDVQMPEMDGFEATRQIRQMEVKANEERKALDLMEGSTFVESHLPVLAMTADVIQATYEECIKSGMDGYVSKPFDEEQLYQAVSRLVVGTKESAV | cytokinin-activated signaling pathway protein phosphorylation plasma membrane cytokine binding phosphorelay sensor kinase activity protein histidine kinase activity Oryza sativa subsp. japonica Cell membrane Cytokinin signaling pathway Kinase Membrane Phosphoprotein Reference proteome Repeat Transferase Transmembrane Transmembrane helix Two-component regulatory system MGKPEARSGW MGKPEARSGWRNAAAAAWVLVAVACAAYMHWHLRRETMDRAEERLVSMCEERARMLQEQFGVTVNHVHALAILISTFHFEKFPSAIDQDTFAKYTARTSFERPLLNGVAYAQRIFHHEREMFENQQGWIMKTMKRQAAPPQDEYAPVIFSQDTVSYLARIDMMSGEEDRENILRARATGKAVLTNPFRLLGSNHLGVVLTFAVYRPGLAADASVEERVEATAGYLGGAFDVESLVENLLSKLAGNQDIVVNVYDVTNASEPMAMYGPQSPDGKVSLFHVSTLDFGDPFRAHEMRCRYRQKPPLPWSAITNPLGTFVIWMLVGYIICAAWSRYDKVSEDCRKMEELKTQAEAADVAKSQFLATVSHEIRTPMNGVLGMLDMLLGTDLSMTQKDYAQTAQMCGRALITLINDVLDRAKIEAGKLELEAVPFDLRSLMDDVISLFSSKSREKCIELAVFVCDDVPKVVIGDPWRYRQILTNLVGNAVKFTERGHVFVRVCLAENSKVEANQVLNGTMNGKDGKVETTANGAFNTLSGFQAADERNNWDYFKLLLSDKEPHMDELECDRSYQNDCDCVTLMISIEDTGVGIPLHAQDRVFTPFMQADSSTSRNYGGTGIGLSISKCLAELMGGQISFTSRPFVGSTFTFSAVLKRSCKDTSSDSKRSLSEALPTAFKGMKAILVDGRPVRGAVTRYHLNRLGIVVKVVNNLSMGLQTLAGQNGVKESREKLSMLFIESDIWRPETDILLLNRLHELKNNGQVHELPKLVLLVTSEADKDRYGSAFDIVMYKPIRASTIASCLQQLLKVVMPERKDNQNRPSFLRSLLIGKNILIVDDNKVNLRVAAAALKKYGAKVHCVESGKDAVSLLQQPHCFDACFMDVQMPEMDGFEATRQIRQMEVKANEERKALDLMEGSTFVESHLPVLAMTADVIQATYEECIKSGMDGYVSKPFDEEQLYQAVSRLVVGTKESAV |
D-ribose catabolic process nucleoside metabolic process | chloroplast; chloroplast nucleoid; chloroplast stroma; nucleus; plastid nucleoid | ATP binding metal ion binding ribokinase activity | Arabidopsis thaliana | 3D-structure ATP-binding Carbohydrate metabolism Chloroplast Kinase Magnesium Metal-binding Nucleotide-binding Plastid Potassium Reference proteome Transferase Transit peptide | MMKGISSVSQ | MMKGISSVSQSINYNPYIEFNRPQLQISTVNPNPAQSRFSRPRSLRVLSLSADPSANRNPKSAVDAHAPPLVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGRLGEDAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEIMSDDDLEIVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELLDSIDILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKPIQQSIIPAAQVVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAAAASLCVQVKGAIPSMPDRKSVLKLLKFSI | D-ribose catabolic process nucleoside metabolic process chloroplast; chloroplast nucleoid; chloroplast stroma; nucleus; plastid nucleoid ATP binding metal ion binding ribokinase activity Arabidopsis thaliana 3D-structure ATP-binding Carbohydrate metabolism Chloroplast Kinase Magnesium Metal-binding Nucleotide-binding Plastid Potassium Reference proteome Transferase Transit peptide MMKGISSVSQ MMKGISSVSQSINYNPYIEFNRPQLQISTVNPNPAQSRFSRPRSLRVLSLSADPSANRNPKSAVDAHAPPLVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGRLGEDAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEIMSDDDLEIVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELLDSIDILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKPIQQSIIPAAQVVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAAAASLCVQVKGAIPSMPDRKSVLKLLKFSI |
chloroplast organization plastid transcription regulation of DNA-templated transcription response to heat response to light stimulus | chloroplast; chloroplast envelope; chloroplast nucleoid; chloroplast thylakoid; chloroplast thylakoid membrane; cytosol | metal ion binding protein disulfide isomerase activity | Arabidopsis thaliana | Alternative splicing Chloroplast Coiled coil Isomerase Metal-binding Plastid Reference proteome Stress response Transcription Transcription regulation Transit peptide Zinc Zinc-finger | MASSSLPLSL | MASSSLPLSLPFPLRSLTSTTRSLPFQCSPLFFSIPSSIVCFSTQNPDREEVRWLREEQRWIREEQRWIREEQRWIRERESLLQEISDLQLRIQSLESRNSQLGNSIPDTISNIAALLQVLKEKNRISESGLSATPMVLESTREQIVEEVEEEEKRVIIAEEKVRVSEPVKKIKRRILKVGSEGDDVQALQEALLKLGFYSGEEDMEFSSFSSGTASAVKTWQASLGVREDGVMTAELLQRLFMDEDVETDKDEASTMKKEEAGNGAVFTSVTQVPEKKQSIVKDQSDREVDVTQNRVFLLGENRWEDPSRLIGRNKPVDRSESTNTKTRCITCRGEGRLMCLECDGTGEPNIEPQFMEWVGEDTKCPYCEGLGYTVCDVCDGKKNL | chloroplast organization plastid transcription regulation of DNA-templated transcription response to heat response to light stimulus chloroplast; chloroplast envelope; chloroplast nucleoid; chloroplast thylakoid; chloroplast thylakoid membrane; cytosol metal ion binding protein disulfide isomerase activity Arabidopsis thaliana Alternative splicing Chloroplast Coiled coil Isomerase Metal-binding Plastid Reference proteome Stress response Transcription Transcription regulation Transit peptide Zinc Zinc-finger MASSSLPLSL MASSSLPLSLPFPLRSLTSTTRSLPFQCSPLFFSIPSSIVCFSTQNPDREEVRWLREEQRWIREEQRWIREEQRWIRERESLLQEISDLQLRIQSLESRNSQLGNSIPDTISNIAALLQVLKEKNRISESGLSATPMVLESTREQIVEEVEEEEKRVIIAEEKVRVSEPVKKIKRRILKVGSEGDDVQALQEALLKLGFYSGEEDMEFSSFSSGTASAVKTWQASLGVREDGVMTAELLQRLFMDEDVETDKDEASTMKKEEAGNGAVFTSVTQVPEKKQSIVKDQSDREVDVTQNRVFLLGENRWEDPSRLIGRNKPVDRSESTNTKTRCITCRGEGRLMCLECDGTGEPNIEPQFMEWVGEDTKCPYCEGLGYTVCDVCDGKKNL |
DNA repair protein repair | cytoplasm | protein deglycase activity thiolester hydrolase activity zinc ion binding | Escherichia coli O1:K1 / APEC | Cytoplasm DNA damage DNA repair Hydrolase Metal-binding Reference proteome Stress response Zinc | MTVQKSKNPQ | MTVQKSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESEDVAAALQWAIENDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG | DNA repair protein repair cytoplasm protein deglycase activity thiolester hydrolase activity zinc ion binding Escherichia coli O1:K1 / APECCytoplasm DNA damage DNA repair Hydrolase Metal-binding Reference proteome Stress response Zinc MTVQKSKNPQ MTVQKSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESEDVAAALQWAIENDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG |
cell adhesion zinc ion transport | periplasmic space | zinc ion binding | Paracoccus denitrificans | 3D-structure Disulfide bond Ion transport Metal-binding Periplasm Reference proteome Signal Transport Zinc Zinc transport | MKDWLFRIAT | MKDWLFRIATCSIMTFSSLAAAQAEPLDVVATFSIIGDFAAKVGGDRIRLNVLVGPDSDTHVYEPRPADAIALAGADVVLTNGLEFEGFLTRLIAASGTDAAVATLTDGVETMEEPGGGHYHYIDGKAVFHAGAHDPHAWQAVPNAKVYVQNIAAAFCAADAEGCAAYQANAARYIGELDALDTEIRAAIAALPQDRRTVVVAHNAFRYFEAAYGVHFLSPQGVSTESEAAAADVAGLIREIRARNASAIFAENISDTRLLEQIAREAGLPLAGTLYSDALSGPDGPASNYIAMMRHNAGAIAAALAAR | cell adhesion zinc ion transport periplasmic space zinc ion binding Paracoccus denitrificans 3D-structure Disulfide bond Ion transport Metal-binding Periplasm Reference proteome Signal Transport Zinc Zinc transport MKDWLFRIAT MKDWLFRIATCSIMTFSSLAAAQAEPLDVVATFSIIGDFAAKVGGDRIRLNVLVGPDSDTHVYEPRPADAIALAGADVVLTNGLEFEGFLTRLIAASGTDAAVATLTDGVETMEEPGGGHYHYIDGKAVFHAGAHDPHAWQAVPNAKVYVQNIAAAFCAADAEGCAAYQANAARYIGELDALDTEIRAAIAALPQDRRTVVVAHNAFRYFEAAYGVHFLSPQGVSTESEAAAADVAGLIREIRARNASAIFAENISDTRLLEQIAREAGLPLAGTLYSDALSGPDGPASNYIAMMRHNAGAIAAALAAR |
cellular response to dexamethasone stimulus muscle cell cellular homeostasis myoblast migration involved in skeletal muscle regeneration negative regulation of insulin receptor signaling pathway negative regulation of myoblast differentiation negative regulation of myoblast proliferation negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of satellite cell differentiation negative regulation of skeletal muscle satellite cell proliferation negative regulation of skeletal muscle tissue growth positive regulation of DNA-templated transcription positive regulation of lamellipodium assembly positive regulation of macrophage chemotaxis skeletal muscle satellite cell differentiation transforming growth factor beta receptor signaling pathway | extracellular space | cytokine activity growth factor activity heparin binding identical protein binding protein homodimerization activity | Macaca mulatta | Cleavage on pair of basic residues Cytokine Disulfide bond Glycoprotein Growth factor Heparin-binding Reference proteome Secreted Signal | MQKLQLCVYI | MQKLQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS | cellular response to dexamethasone stimulus muscle cell cellular homeostasis myoblast migration involved in skeletal muscle regeneration negative regulation of insulin receptor signaling pathway negative regulation of myoblast differentiation negative regulation of myoblast proliferation negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of satellite cell differentiation negative regulation of skeletal muscle satellite cell proliferation negative regulation of skeletal muscle tissue growth positive regulation of DNA-templated transcription positive regulation of lamellipodium assembly positive regulation of macrophage chemotaxis skeletal muscle satellite cell differentiation transforming growth factor beta receptor signaling pathway extracellular space cytokine activity growth factor activity heparin binding identical protein binding protein homodimerization activity Macaca mulatta Cleavage on pair of basic residues Cytokine Disulfide bond Glycoprotein Growth factor Heparin-binding Reference proteome Secreted Signal MQKLQLCVYI MQKLQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS |
protein O-linked glycosylation via serine | cytoplasm; plasma membrane; protein N-acetylglucosaminyltransferase complex | glycosyltransferase activity nucleotide binding | Streptococcus parasanguinis | Cell membrane Cytoplasm Direct protein sequencing Glycosyltransferase Membrane Nucleotide-binding Transferase | MTIYNINLGI | MTIYNINLGIGWASSGVEYAQAYRAQILRSLGMPAKFIFTNMFQSENLEHFTKNIGFEDNEIIWLYGYFTDVKISGTTYKKDDLEATFSQCPTKKEASSDRKLIRYYFENQELYINASLYGENQEYVQRVEYVVKGKLIRKDYYSYTKVFSEFYSPGENGVQLCNRSFYNEDGSIAYEEILSNEKSTFVFSNKICYGLEELLEFMLEDLSLTKSDLILLDRATGIGQVVFENIGAAKLAVVIHAEHFNEKNTDEHNILWNNYYEYQFTNADKVNAFITSTERQKILLEEQFTQYTSLHPKIVAIPVGSLDQLKFPEQSRKSFSMMTGSRLAIEKHIDWLIEGVALAQKRLPELTFDIYGEGGERRKLTELLTKLHAGEFIELKGHKQLDEIYQNYELYLTASTSEGFGLTLMEAVGSGLPIIGFDVPYGNQTFVCSGENGLLIERPKGDDRSRIVQAFADSIYEYFTKFKMADAQQYSYNIAENYKHEKLVERWKDFIEEMLND | protein O-linked glycosylation via serine cytoplasm; plasma membrane; protein N-acetylglucosaminyltransferase complex glycosyltransferase activity nucleotide binding Streptococcus parasanguinisCell membrane Cytoplasm Direct protein sequencing Glycosyltransferase Membrane Nucleotide-binding Transferase MTIYNINLGI MTIYNINLGIGWASSGVEYAQAYRAQILRSLGMPAKFIFTNMFQSENLEHFTKNIGFEDNEIIWLYGYFTDVKISGTTYKKDDLEATFSQCPTKKEASSDRKLIRYYFENQELYINASLYGENQEYVQRVEYVVKGKLIRKDYYSYTKVFSEFYSPGENGVQLCNRSFYNEDGSIAYEEILSNEKSTFVFSNKICYGLEELLEFMLEDLSLTKSDLILLDRATGIGQVVFENIGAAKLAVVIHAEHFNEKNTDEHNILWNNYYEYQFTNADKVNAFITSTERQKILLEEQFTQYTSLHPKIVAIPVGSLDQLKFPEQSRKSFSMMTGSRLAIEKHIDWLIEGVALAQKRLPELTFDIYGEGGERRKLTELLTKLHAGEFIELKGHKQLDEIYQNYELYLTASTSEGFGLTLMEAVGSGLPIIGFDVPYGNQTFVCSGENGLLIERPKGDDRSRIVQAFADSIYEYFTKFKMADAQQYSYNIAENYKHEKLVERWKDFIEEMLND |
exit from mitosis G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle kinetochore assembly mitotic nuclear membrane biogenesis negative regulation of cytoplasmic translation negative regulation of mitotic metaphase/anaphase transition positive regulation of glucose transmembrane transport protein neddylation protein ubiquitination regulation of DNA recombination regulation of exit from mitosis regulation of protein-containing complex assembly resolution of meiotic recombination intermediates SCF-dependent proteasomal ubiquitin-dependent protein catabolic process septin ring assembly silent mating-type cassette heterochromatin formation vacuolar acidification vacuolar proton-transporting V-type ATPase complex assembly | CBF3 complex; kinetochore; nuclear SCF ubiquitin ligase complex; RAVE complex; single-stranded DNA-dependent ATP-dependent DNA helicase complex | DNA replication origin binding ubiquitin protein ligase activity | Aspergillus clavatus | Reference proteome Ubl conjugation pathway | MSTTVTLTSS | MSTTVTLTSSDGVDLTVDRDVAERSVLIKNMLEDLGESGEAIPIPNVNEVVLKKVIEWCTHHKNDPPSTGDDDDSRRKTTDIDEWDQKFMQVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPEEIRKTFNIQNDFTPEEEDQIRRENEWAEE | exit from mitosis G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle kinetochore assembly mitotic nuclear membrane biogenesis negative regulation of cytoplasmic translation negative regulation of mitotic metaphase/anaphase transition positive regulation of glucose transmembrane transport protein neddylation protein ubiquitination regulation of DNA recombination regulation of exit from mitosis regulation of protein-containing complex assembly resolution of meiotic recombination intermediates SCF-dependent proteasomal ubiquitin-dependent protein catabolic process septin ring assembly silent mating-type cassette heterochromatin formation vacuolar acidification vacuolar proton-transporting V-type ATPase complex assembly CBF3 complex; kinetochore; nuclear SCF ubiquitin ligase complex; RAVE complex; single-stranded DNA-dependent ATP-dependent DNA helicase complex DNA replication origin binding ubiquitin protein ligase activity Aspergillus clavatus Reference proteome Ubl conjugation pathway MSTTVTLTSS MSTTVTLTSSDGVDLTVDRDVAERSVLIKNMLEDLGESGEAIPIPNVNEVVLKKVIEWCTHHKNDPPSTGDDDDSRRKTTDIDEWDQKFMQVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPEEIRKTFNIQNDFTPEEEDQIRRENEWAEE |
cell budding cellular response to oxidative stress invasive growth in response to glucose limitation Mo-molybdopterin cofactor biosynthetic process protein urmylation regulation of pseudohyphal growth tRNA wobble position uridine thiolation | cytosol | AMPylase activity ATP binding identical protein binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity thiosulfate sulfurtransferase activity URM1 activating enzyme activity | Aspergillus clavatus | ATP-binding Cytoplasm Metal-binding Molybdenum cofactor biosynthesis Multifunctional enzyme Nucleotide-binding Reference proteome Transferase tRNA processing Zinc | MENLEQTCAS | MENLEQTCASLRAQIAATEAQLAGLKRDLEVAEQAAAEIKAQDVKSTGIREEGSEKKNPWPLLSEEYKRYGRQMIVPQLGLQGQLKLRSARVLIVGAGGLGCPAALYLAGAGVGTLGLVDGDTVEHSNLHRQVLHRSKNVGKFKVDSAIEYLRELNPHPTYVPYRAHLTPQEAPEIFKDYDIVLDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLIVLNNPPRPVGDKSGGPCYRCVFPKPPPATSVVSCADGGIIGPVVGTMGVLQAIEAIKVITSSPADETSASPPSLLIFSAYSTPPFRSIKIRSRRANCAVCSAEASVTVETLKTGSTDYVFFCGVAGPETLLRPEERITPLEFKKKHPGQVSHEQELGGSKEPTIIDVREQVQFDICSLDNSINIPISTILSSAASPTTSTPESLPSWLPHDIVSSSSTDPIYVVCRLGNDSQIAVRKMKELGLDQGGKRFICDIQGGLRAWREQIDPDWPEY | cell budding cellular response to oxidative stress invasive growth in response to glucose limitation Mo-molybdopterin cofactor biosynthetic process protein urmylation regulation of pseudohyphal growth tRNA wobble position uridine thiolation cytosol AMPylase activity ATP binding identical protein binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity thiosulfate sulfurtransferase activity URM1 activating enzyme activity Aspergillus clavatus ATP-binding Cytoplasm Metal-binding Molybdenum cofactor biosynthesis Multifunctional enzyme Nucleotide-binding Reference proteome Transferase tRNA processing Zinc MENLEQTCAS MENLEQTCASLRAQIAATEAQLAGLKRDLEVAEQAAAEIKAQDVKSTGIREEGSEKKNPWPLLSEEYKRYGRQMIVPQLGLQGQLKLRSARVLIVGAGGLGCPAALYLAGAGVGTLGLVDGDTVEHSNLHRQVLHRSKNVGKFKVDSAIEYLRELNPHPTYVPYRAHLTPQEAPEIFKDYDIVLDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLIVLNNPPRPVGDKSGGPCYRCVFPKPPPATSVVSCADGGIIGPVVGTMGVLQAIEAIKVITSSPADETSASPPSLLIFSAYSTPPFRSIKIRSRRANCAVCSAEASVTVETLKTGSTDYVFFCGVAGPETLLRPEERITPLEFKKKHPGQVSHEQELGGSKEPTIIDVREQVQFDICSLDNSINIPISTILSSAASPTTSTPESLPSWLPHDIVSSSSTDPIYVVCRLGNDSQIAVRKMKELGLDQGGKRFICDIQGGLRAWREQIDPDWPEY |
exit from mitosis G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle kinetochore assembly mitotic nuclear membrane biogenesis negative regulation of cytoplasmic translation negative regulation of mitotic metaphase/anaphase transition positive regulation of glucose transmembrane transport protein neddylation protein ubiquitination regulation of DNA recombination regulation of exit from mitosis regulation of protein-containing complex assembly resolution of meiotic recombination intermediates SCF-dependent proteasomal ubiquitin-dependent protein catabolic process septin ring assembly silent mating-type cassette heterochromatin formation vacuolar acidification vacuolar proton-transporting V-type ATPase complex assembly | CBF3 complex; kinetochore; nuclear SCF ubiquitin ligase complex; RAVE complex; single-stranded DNA-dependent ATP-dependent DNA helicase complex | DNA replication origin binding ubiquitin protein ligase activity | Neosartorya fischeri | Reference proteome Ubl conjugation pathway | MTTVTLTSSD | MTTVTLTSSDGVDITVDRDVAERSILIKNMLEDLGESDEAIPIPNVNEVVLKKVIEWCTHHKNDPPSTGDDDDSRRKTTDIDEWDQKFMQVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPEEIRKTFNIQNDFTPEEEDQIRRENEWAEE | exit from mitosis G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle kinetochore assembly mitotic nuclear membrane biogenesis negative regulation of cytoplasmic translation negative regulation of mitotic metaphase/anaphase transition positive regulation of glucose transmembrane transport protein neddylation protein ubiquitination regulation of DNA recombination regulation of exit from mitosis regulation of protein-containing complex assembly resolution of meiotic recombination intermediates SCF-dependent proteasomal ubiquitin-dependent protein catabolic process septin ring assembly silent mating-type cassette heterochromatin formation vacuolar acidification vacuolar proton-transporting V-type ATPase complex assembly CBF3 complex; kinetochore; nuclear SCF ubiquitin ligase complex; RAVE complex; single-stranded DNA-dependent ATP-dependent DNA helicase complex DNA replication origin binding ubiquitin protein ligase activity Neosartorya fischeri Reference proteome Ubl conjugation pathway MTTVTLTSSD MTTVTLTSSDGVDITVDRDVAERSILIKNMLEDLGESDEAIPIPNVNEVVLKKVIEWCTHHKNDPPSTGDDDDSRRKTTDIDEWDQKFMQVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPEEIRKTFNIQNDFTPEEEDQIRRENEWAEE |
cell budding cellular response to oxidative stress invasive growth in response to glucose limitation Mo-molybdopterin cofactor biosynthetic process protein urmylation regulation of pseudohyphal growth tRNA wobble position uridine thiolation | cytosol | AMPylase activity ATP binding identical protein binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity thiosulfate sulfurtransferase activity URM1 activating enzyme activity | Neosartorya fischeri | ATP-binding Cytoplasm Metal-binding Molybdenum cofactor biosynthesis Multifunctional enzyme Nucleotide-binding Reference proteome Transferase tRNA processing Zinc | MENLEQTCAS | MENLEQTCASLRAQIAATEAQLAGLKRELEIAEQAAADVKAQDTTITITADEGRINGTRTWPLLSEEYKRYGRQMIVPQVGLQGQLKLRSARVLIVGAGGLGCPAALYLAGAGVGTLGLVDGDTVENSNLHRQVLHRSKNVGKFKVDSAIEYLREAHLTPQEAPSIFKDYDIILDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLMVLNYPPRPVGDKSGGPCYRCVFPKPPPANSVVSCADGGILGPVVGTMGVLQALEAIKVITSPAVNPSASPPSLLIFSAYSTPPFRTIRLRARRANCAVCSADASVTLETLKIGSTDYVFFCGVAGLEATLSPEERISPLELRKRHPKEVPQDGGSISKEPTIIDVREKVQFDICNLEHSVNIPISTILSSASNAANADANAQPSLPSWLPRELASADSTNPIYVVCRHGNDSQIAVRRLKELGLDRGGQRYVGDIQGGLRAWREQIDPDWPEY | cell budding cellular response to oxidative stress invasive growth in response to glucose limitation Mo-molybdopterin cofactor biosynthetic process protein urmylation regulation of pseudohyphal growth tRNA wobble position uridine thiolation cytosol AMPylase activity ATP binding identical protein binding metal ion binding molybdopterin-synthase adenylyltransferase activity molybdopterin-synthase sulfurtransferase activity thiosulfate sulfurtransferase activity URM1 activating enzyme activity Neosartorya fischeri ATP-binding Cytoplasm Metal-binding Molybdenum cofactor biosynthesis Multifunctional enzyme Nucleotide-binding Reference proteome Transferase tRNA processing Zinc MENLEQTCAS MENLEQTCASLRAQIAATEAQLAGLKRELEIAEQAAADVKAQDTTITITADEGRINGTRTWPLLSEEYKRYGRQMIVPQVGLQGQLKLRSARVLIVGAGGLGCPAALYLAGAGVGTLGLVDGDTVENSNLHRQVLHRSKNVGKFKVDSAIEYLREAHLTPQEAPSIFKDYDIILDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLMVLNYPPRPVGDKSGGPCYRCVFPKPPPANSVVSCADGGILGPVVGTMGVLQALEAIKVITSPAVNPSASPPSLLIFSAYSTPPFRTIRLRARRANCAVCSADASVTLETLKIGSTDYVFFCGVAGLEATLSPEERISPLELRKRHPKEVPQDGGSISKEPTIIDVREKVQFDICNLEHSVNIPISTILSSASNAANADANAQPSLPSWLPRELASADSTNPIYVVCRHGNDSQIAVRRLKELGLDRGGQRYVGDIQGGLRAWREQIDPDWPEY |
cell-cell signaling involved in cell fate commitment phloem or xylem histogenesis procambium histogenesis xylem development | apoplast; plasma membrane | receptor serine/threonine kinase binding | Zinnia elegans | Cell membrane Developmental protein Differentiation Direct protein sequencing Glycoprotein Hydroxylation Membrane Secreted Signal Transmembrane Transmembrane helix | MDIDLLWSFG | MDIDLLWSFGGWFFILFPETINYCMAKLRSTSQISHFTNPRSCSSLFFVALLIITILITMLQSSTSMEVTSLPTHQPTSSNSHDESSTSSTATTTTDLHPKRTHHQSHPKPTRSFEAGAHEVPSGPNPISNR | cell-cell signaling involved in cell fate commitment phloem or xylem histogenesis procambium histogenesis xylem development apoplast; plasma membrane receptor serine/threonine kinase binding Zinnia elegans Cell membrane Developmental protein Differentiation Direct protein sequencing Glycoprotein Hydroxylation Membrane Secreted Signal Transmembrane Transmembrane helix MDIDLLWSFG MDIDLLWSFGGWFFILFPETINYCMAKLRSTSQISHFTNPRSCSSLFFVALLIITILITMLQSSTSMEVTSLPTHQPTSSNSHDESSTSSTATTTTDLHPKRTHHQSHPKPTRSFEAGAHEVPSGPNPISNR |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Yersinia enterocolitica serotype O:8 / biotype 1B | Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase | MLYQSETLQL | MLYQSETLQLHWLENGIAELVFDAPGSVNKLDTQTVANLGEALVVLEKQSELKGLLLRSAKAAFIVGADITEFLSLFNEPPEKLHQWLVFANDIFNRLEDLPVPTIAAINGYALGGGCECILATDFRVASPEARIGLPETKLGIMPGFGGSVRLPRLLGADSALEIIAAGKDIIAKDALKVGLVDAVVAPEKLVDAALSILNQAIDGKLDWQAARRPKLEPLKLNPTEAAMCFTIAKGMVMQVAGKHYPAPLTAVKTIEAAAKFGRAEALILETNSFVPLAGSNEARALVGIFLNDQYVKGQAKKLSKGVSAPKQAAVLGAGIMGGGIAYQSALKGVPVIMKDINDKSLTLGMNEAAKLLNKQLERGKIDGLKMANILATIQPTLDYAGIERAQVIVEAVVENPKVKAAVLAEVETLIGEETVLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGTKTSDKTIAAVVAYATQMGKTPIVVNDCPGFFVNRVLFPYLAGFGMLVRDGADFRQIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAVGFPERMNKDYRDAVDVMFDNQRFGQKNGQGFYRYTQDTKGKPRKENDEQVDALLAQVSQPLQKFSDDDIIARTMIPMINEVVRCLEEGIIASPAEGDMALVYGLGFPPFHGGVFRYLDTIGSANYVEMAQRYTHLGALYQVPPGLRAKAEHNESYYPVAAALLDVSISQPA | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Yersinia enterocolitica serotype O:8 / biotype 1B Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase MLYQSETLQL MLYQSETLQLHWLENGIAELVFDAPGSVNKLDTQTVANLGEALVVLEKQSELKGLLLRSAKAAFIVGADITEFLSLFNEPPEKLHQWLVFANDIFNRLEDLPVPTIAAINGYALGGGCECILATDFRVASPEARIGLPETKLGIMPGFGGSVRLPRLLGADSALEIIAAGKDIIAKDALKVGLVDAVVAPEKLVDAALSILNQAIDGKLDWQAARRPKLEPLKLNPTEAAMCFTIAKGMVMQVAGKHYPAPLTAVKTIEAAAKFGRAEALILETNSFVPLAGSNEARALVGIFLNDQYVKGQAKKLSKGVSAPKQAAVLGAGIMGGGIAYQSALKGVPVIMKDINDKSLTLGMNEAAKLLNKQLERGKIDGLKMANILATIQPTLDYAGIERAQVIVEAVVENPKVKAAVLAEVETLIGEETVLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGTKTSDKTIAAVVAYATQMGKTPIVVNDCPGFFVNRVLFPYLAGFGMLVRDGADFRQIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAVGFPERMNKDYRDAVDVMFDNQRFGQKNGQGFYRYTQDTKGKPRKENDEQVDALLAQVSQPLQKFSDDDIIARTMIPMINEVVRCLEEGIIASPAEGDMALVYGLGFPPFHGGVFRYLDTIGSANYVEMAQRYTHLGALYQVPPGLRAKAEHNESYYPVAAALLDVSISQPA |
Fc receptor-mediated immune complex endocytosis humoral immune response mediated by circulating immunoglobulin immunoglobulin transcytosis in epithelial cells negative regulation of extrinsic apoptotic signaling pathway negative regulation of lymphocyte apoptotic process regulation of B cell receptor signaling pathway | cell surface; early endosome membrane; external side of plasma membrane; lysosomal membrane; plasma membrane; trans-Golgi network membrane | high-affinity IgM receptor activity IgM binding polymeric immunoglobulin binding | Mus musculus | Cell membrane Disulfide bond Endosome Golgi apparatus Immunity Immunoglobulin domain Lysosome Membrane Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MDFWLWLLYF | MDFWLWLLYFLPVSGALRVLPEVQLNVEWGGSIIIECPLPQLHVRMYLCRQMAKPGICSTVVSNTFVKKEYERRVTLTPCLDKKLFLVEMTQLTENDDGIYACGVGMKTDKGKTQKITLNVHNEYPEPFWEDEWTSERPRWLHRFLQHQMPWLHGSEHPSSSGVIAKVTTPAPKTEAPPVHQPSSITSVTQHPRVYRAFSVSATKSPALLPATTASKTSTQQAIRPLEASYSHHTRLHEQRTRHHGPHYGREDRGLHIPIPEFHILIPTFLGFLLLVLLGLVVKRAIQRRRASSRRAGRLAMRRRGRGASRPFPTQRRDASQRPRSQNNVYSACPRRARGPDSLGPAEAPLLNAPASASPASPQVLEAPWPHTPSLKMSCEYVSLGYQPAVNLEDPDSDDYINIPDPSHLPSYAPGPRSSCP | Fc receptor-mediated immune complex endocytosis humoral immune response mediated by circulating immunoglobulin immunoglobulin transcytosis in epithelial cells negative regulation of extrinsic apoptotic signaling pathway negative regulation of lymphocyte apoptotic process regulation of B cell receptor signaling pathway cell surface; early endosome membrane; external side of plasma membrane; lysosomal membrane; plasma membrane; trans-Golgi network membrane high-affinity IgM receptor activity IgM binding polymeric immunoglobulin binding Mus musculus Cell membrane Disulfide bond Endosome Golgi apparatus Immunity Immunoglobulin domain Lysosome Membrane Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix MDFWLWLLYF MDFWLWLLYFLPVSGALRVLPEVQLNVEWGGSIIIECPLPQLHVRMYLCRQMAKPGICSTVVSNTFVKKEYERRVTLTPCLDKKLFLVEMTQLTENDDGIYACGVGMKTDKGKTQKITLNVHNEYPEPFWEDEWTSERPRWLHRFLQHQMPWLHGSEHPSSSGVIAKVTTPAPKTEAPPVHQPSSITSVTQHPRVYRAFSVSATKSPALLPATTASKTSTQQAIRPLEASYSHHTRLHEQRTRHHGPHYGREDRGLHIPIPEFHILIPTFLGFLLLVLLGLVVKRAIQRRRASSRRAGRLAMRRRGRGASRPFPTQRRDASQRPRSQNNVYSACPRRARGPDSLGPAEAPLLNAPASASPASPQVLEAPWPHTPSLKMSCEYVSLGYQPAVNLEDPDSDDYINIPDPSHLPSYAPGPRSSCP |
fatty acid alpha-oxidation isoleucine biosynthetic process valine biosynthetic process | acetolactate synthase complex; endoplasmic reticulum membrane; membrane | acetolactate synthase activity flavin adenine dinucleotide binding lyase activity magnesium ion binding thiamine pyrophosphate binding | Homo sapiens | Endoplasmic reticulum Fatty acid metabolism Lipid metabolism Lyase Magnesium Membrane Metal-binding Reference proteome Thiamine pyrophosphate Transmembrane Transmembrane helix | METPAAAAPA | METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIPVMALVGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILIGRTDFRDGSIAV | fatty acid alpha-oxidation isoleucine biosynthetic process valine biosynthetic process acetolactate synthase complex; endoplasmic reticulum membrane; membrane acetolactate synthase activity flavin adenine dinucleotide binding lyase activity magnesium ion binding thiamine pyrophosphate binding Homo sapiens Endoplasmic reticulum Fatty acid metabolism Lipid metabolism Lyase Magnesium Membrane Metal-binding Reference proteome Thiamine pyrophosphate Transmembrane Transmembrane helix METPAAAAPA METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIPVMALVGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILIGRTDFRDGSIAV |
protein polyubiquitination | nucleoplasm; nucleus; plasma membrane | ATP binding ubiquitin conjugating enzyme activity | Homo sapiens | ATP-binding Chromosomal rearrangement Nucleotide-binding Nucleus Reference proteome Transferase Ubl conjugation pathway | MKELQDIARL | MKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG | protein polyubiquitination nucleoplasm; nucleus; plasma membrane ATP binding ubiquitin conjugating enzyme activity Homo sapiens ATP-binding Chromosomal rearrangement Nucleotide-binding Nucleus Reference proteome Transferase Ubl conjugation pathway MKELQDIARL MKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG |
cellular response to mechanical stimulus mRNA processing negative regulation of DNA binding PML body organization positive regulation of RNA splicing positive regulation of translational initiation ribosome hibernation RNA splicing | Cajal body; cytoplasm; cytoplasmic stress granule; cytosol; Gemini of coiled bodies; nuclear membrane; nuclear speck; nucleolus; nucleus; sarcomere; sarcoplasm; synapse | ribosome binding RNA binding SUMO binding translation elongation factor binding | Rattus norvegicus | Coiled coil Cytoplasm Isopeptide bond Methylation mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome RNA-binding Transcription Transcription regulation Translation regulation Ubl conjugation | MKGALGSPVA | MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAASGAGHRGGRSPAVASGHRPGAAGRRESQKERKSLAVSSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDNRGTDVVLDRAERRSYREYRPYDTERQAESTAEKFTDEKPVDRFDRDRPLRGRGGPRGGLRNRGRGGPGNRAFDSFDQRGKRDFERYGSSDKANRMEDSMGGCGVRTWGSGKDTSDTEPPAPMEETSMMEECQGVLDEESASKVPELEVEEENQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDIVKDDYEDESHVFRKAANDITSQLEINFGNLPRPGRGARGSTRGGRGRIRRTENYGPRAEVVTQDVAPNPDDPEDFPALA | cellular response to mechanical stimulus mRNA processing negative regulation of DNA binding PML body organization positive regulation of RNA splicing positive regulation of translational initiation ribosome hibernation RNA splicing Cajal body; cytoplasm; cytoplasmic stress granule; cytosol; Gemini of coiled bodies; nuclear membrane; nuclear speck; nucleolus; nucleus; sarcomere; sarcoplasm; synapse ribosome binding RNA binding SUMO binding translation elongation factor binding Rattus norvegicus Coiled coil Cytoplasm Isopeptide bond Methylation mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome RNA-binding Transcription Transcription regulation Translation regulation Ubl conjugation MKGALGSPVA MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAASGAGHRGGRSPAVASGHRPGAAGRRESQKERKSLAVSSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDNRGTDVVLDRAERRSYREYRPYDTERQAESTAEKFTDEKPVDRFDRDRPLRGRGGPRGGLRNRGRGGPGNRAFDSFDQRGKRDFERYGSSDKANRMEDSMGGCGVRTWGSGKDTSDTEPPAPMEETSMMEECQGVLDEESASKVPELEVEEENQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDIVKDDYEDESHVFRKAANDITSQLEINFGNLPRPGRGARGSTRGGRGRIRRTENYGPRAEVVTQDVAPNPDDPEDFPALA |
anterior/posterior pattern specification anterior/posterior pattern specification involved in pronephros development digestive tract morphogenesis embryonic digestive tract development endocrine pancreas development endoderm formation glucose homeostasis hepaticobiliary system development hindbrain development hindbrain morphogenesis insulin secretion intrahepatic bile duct development liver development liver morphogenesis otic placode formation otic vesicle formation otolith development otolith morphogenesis pancreas development pancreas regeneration positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II rhombomere 5 development rhombomere 5 morphogenesis rhombomere 6 development rhombomere 6 morphogenesis semicircular canal morphogenesis tube formation type B pancreatic cell development | nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Danio rerio | Activator Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MFANMVSKLT | MFANMVSKLTSLQQELLSALLDSGVTKDVLLQALEDLDPSPSAFGVKLDSLQMSPSGSKLSDTDSKPVFHTLTNGHSKGKLSGDEGSEDGDDYDTPPILKELQSQNTEEAAEQRAEIERMLAEDPWRAARMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQATQGSGATMLDKGNQDQVLLFFSEFSQSGQGMVQPGDDAAIEPACKKLRRNRFKWGPASQQILYQAYERQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSGPAHSLNSLLSHSSPHHPQTSSSPPSKMQGVRYSQQGPGEVTSSTTINHHSSNAMSTSQSVLQQVSPGALDPSHSLLSPDAKMISVSGGGLPPVSTLTNIHASHHVHQQTPNLIMPLSGVMAIAQSLNTSQAQTVPVINSVAGSLAALQPVQFSQQLNSQHQQLMQQSSGHMSQQSFMASVSHSHMYPHKQEPPQYSHSSRFPPAMVVTDANSLSTLSSMSSSKQCPLQAW | anterior/posterior pattern specification anterior/posterior pattern specification involved in pronephros development digestive tract morphogenesis embryonic digestive tract development endocrine pancreas development endoderm formation glucose homeostasis hepaticobiliary system development hindbrain development hindbrain morphogenesis insulin secretion intrahepatic bile duct development liver development liver morphogenesis otic placode formation otic vesicle formation otolith development otolith morphogenesis pancreas development pancreas regeneration positive regulation of DNA-templated transcription regulation of transcription by RNA polymerase II rhombomere 5 development rhombomere 5 morphogenesis rhombomere 6 development rhombomere 6 morphogenesis semicircular canal morphogenesis tube formation type B pancreatic cell development nucleus DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding Danio rerio Activator Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation MFANMVSKLT MFANMVSKLTSLQQELLSALLDSGVTKDVLLQALEDLDPSPSAFGVKLDSLQMSPSGSKLSDTDSKPVFHTLTNGHSKGKLSGDEGSEDGDDYDTPPILKELQSQNTEEAAEQRAEIERMLAEDPWRAARMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQATQGSGATMLDKGNQDQVLLFFSEFSQSGQGMVQPGDDAAIEPACKKLRRNRFKWGPASQQILYQAYERQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSGPAHSLNSLLSHSSPHHPQTSSSPPSKMQGVRYSQQGPGEVTSSTTINHHSSNAMSTSQSVLQQVSPGALDPSHSLLSPDAKMISVSGGGLPPVSTLTNIHASHHVHQQTPNLIMPLSGVMAIAQSLNTSQAQTVPVINSVAGSLAALQPVQFSQQLNSQHQQLMQQSSGHMSQQSFMASVSHSHMYPHKQEPPQYSHSSRFPPAMVVTDANSLSTLSSMSSSKQCPLQAW |
collagen fibril organization endothelial cell migration endothelial cell proliferation epithelial to mesenchymal transition heterochromatin organization negative regulation of DNA-templated transcription negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II peptidyl-lysine oxidation positive regulation of chondrocyte differentiation positive regulation of epithelial to mesenchymal transition response to hypoxia sprouting angiogenesis | basement membrane; chromatin; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular space; membrane; nucleus | calcium ion binding copper ion binding protein-lysine 6-oxidase activity | Danio rerio | Basement membrane Calcium Chromatin regulator Chromosome Copper Disulfide bond Endoplasmic reticulum Extracellular matrix Glycoprotein LTQ Metal-binding Nucleus Oxidoreductase Reference proteome Repeat Repressor Secreted Signal TPQ Transcription Transcription regulation | MLALWSISFV | MLALWSISFVLLCSWRLSYAQYEHLGFAIAYQEPEQDLYTPPELPADTPRIQLRLAGEKRKHNEGRVEVFYEGEWGTVCDDDFTIHAAQVICRELGYFEAISWSPSSKYGKGEGRIWFDNVHCKGKEKSLAQCESNGIGVSDCKHSEDVGVVCSDKRIPGFKFVNTLTNNINSLNIQVEDVRIRPILASYRKRIPVTEGYVEVKDGGKWKQICDDEWTQMNSRVICGMFGFPGQKRYNTRVYKMFARRRKPSYWDYTINCTGKEAHLSSCTLGHTLSNSTCEEGTPVVVSCIPGRAFAPTPMTGYKKAFRQEQPLVRLRGGAVVGEGRVEVLKNGEWGTICDDNWNLLAATVVCRELGFGSAKEALSGGQLGQGMGPVHMNEVQCSGFEKSVTECSFNMEKDSEGCSHEEDAGVKCNVPAMGFQQRLRLSGGRNPFEGRVEVLVERNGSLVWGTVCGEGWTTMEAMVVCRQLGLGFASNAFQETWYWPGAVNADAVVMSGVRCAGTEMSLSHCLHHGEYLSCPKGGGRFAAGVSCSETAPDLVLNPQVVEQTTYLEDRPMFMLQCAYEENCLASTSSATPANSPRRLLRFSSQIHNNGQSDFRPKISRENWVWHDCHRHYHSMEVFTHYDLLSTNGTKVAEGHKASFCLEDSECDEGIEKRYECANFGEQGITVGCWDTYRHDIDCQWVDITDVKPGDYIFQIVINPNYEVAESDYTNNIVKCRCRYDGHRIWMYNCHIGGSFSAETEDTFPGLINNQVTHR | collagen fibril organization endothelial cell migration endothelial cell proliferation epithelial to mesenchymal transition heterochromatin organization negative regulation of DNA-templated transcription negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II peptidyl-lysine oxidation positive regulation of chondrocyte differentiation positive regulation of epithelial to mesenchymal transition response to hypoxia sprouting angiogenesis basement membrane; chromatin; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular space; membrane; nucleus calcium ion binding copper ion binding protein-lysine 6-oxidase activity Danio rerio Basement membrane Calcium Chromatin regulator Chromosome Copper Disulfide bond Endoplasmic reticulum Extracellular matrix Glycoprotein LTQ Metal-binding Nucleus Oxidoreductase Reference proteome Repeat Repressor Secreted Signal TPQ Transcription Transcription regulation MLALWSISFV MLALWSISFVLLCSWRLSYAQYEHLGFAIAYQEPEQDLYTPPELPADTPRIQLRLAGEKRKHNEGRVEVFYEGEWGTVCDDDFTIHAAQVICRELGYFEAISWSPSSKYGKGEGRIWFDNVHCKGKEKSLAQCESNGIGVSDCKHSEDVGVVCSDKRIPGFKFVNTLTNNINSLNIQVEDVRIRPILASYRKRIPVTEGYVEVKDGGKWKQICDDEWTQMNSRVICGMFGFPGQKRYNTRVYKMFARRRKPSYWDYTINCTGKEAHLSSCTLGHTLSNSTCEEGTPVVVSCIPGRAFAPTPMTGYKKAFRQEQPLVRLRGGAVVGEGRVEVLKNGEWGTICDDNWNLLAATVVCRELGFGSAKEALSGGQLGQGMGPVHMNEVQCSGFEKSVTECSFNMEKDSEGCSHEEDAGVKCNVPAMGFQQRLRLSGGRNPFEGRVEVLVERNGSLVWGTVCGEGWTTMEAMVVCRQLGLGFASNAFQETWYWPGAVNADAVVMSGVRCAGTEMSLSHCLHHGEYLSCPKGGGRFAAGVSCSETAPDLVLNPQVVEQTTYLEDRPMFMLQCAYEENCLASTSSATPANSPRRLLRFSSQIHNNGQSDFRPKISRENWVWHDCHRHYHSMEVFTHYDLLSTNGTKVAEGHKASFCLEDSECDEGIEKRYECANFGEQGITVGCWDTYRHDIDCQWVDITDVKPGDYIFQIVINPNYEVAESDYTNNIVKCRCRYDGHRIWMYNCHIGGSFSAETEDTFPGLINNQVTHR |
allantoin metabolic process purine nucleobase metabolic process urate catabolic process | peroxisome | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity | Danio rerio | 3D-structure Decarboxylase Lyase Peroxisome Purine metabolism Reference proteome | MDINVVNALA | MDINVVNALAYEDFVKLFGNVVEKCPLISAAIWSYRPFKDLADIEARISEFIHSLPDSGKEGILRCHPDLAGRDLQSGTLTPESQEEQSQAGMTTLDSAEIVHMYRLNSEYKERFGFPFVICARLNNKADIVRQLSERLKNRRTAELECAIEEVKKICSLRLHSIVLSDIQTKL | allantoin metabolic process purine nucleobase metabolic process urate catabolic process peroxisome 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity Danio rerio 3D-structure Decarboxylase Lyase Peroxisome Purine metabolism Reference proteome MDINVVNALA MDINVVNALAYEDFVKLFGNVVEKCPLISAAIWSYRPFKDLADIEARISEFIHSLPDSGKEGILRCHPDLAGRDLQSGTLTPESQEEQSQAGMTTLDSAEIVHMYRLNSEYKERFGFPFVICARLNNKADIVRQLSERLKNRRTAELECAIEEVKKICSLRLHSIVLSDIQTKL |
chromatin organization cranial skeletal system development negative regulation of DNA-templated transcription Notch signaling pathway protein deubiquitination protein K48-linked deubiquitination regulation of cell cycle regulation of cell growth ubiquitin-dependent protein catabolic process | cytoplasm; nucleus; PR-DUB complex | chromatin binding cysteine-type deubiquitinase activity | Danio rerio | Chromatin regulator Cytoplasm Hydrolase Nucleus Protease Reference proteome Thiol protease Ubl conjugation pathway | MNKGWLELES | MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQSPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDDDIVNDMFFAHQLIPNSCATHALLSVLLNCSGVELGMTLSRMKAFTKGFNPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKDRLFELDGLKAYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYESKLDILKRNRQIILEGLQQIREKKVIRMTQQESGQDRKQQDSSSSEDTPPVVKKEEVQETPIPSGAEQATPTEAQEGAASLPSPAGKVRSMAKPALPAGGAPPPAPLPAPSTNTIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRPPQPPYSDDEDDYDDEEEECSTAGVTNSRVRRKLGLRTRTMSRTAVGGVAAMEGQLALSVLAEKLKKEVQRKDALATTGSTPLNVRTEGRTGGISITSACQPSPTPSNESTDTASEIGSAFNSPLRSPARSQATTRPSSPVASHVGRVLFGEEEGLPRLDARHNRAVRDLGVLVSSTQLQLQEDGVIFALPPTEALEGLKKVGGVDKKKKEEASGPGGEEEVKEGPSVEMKAEDVKESVDVKPEKENLPTTDVENSTKPPGEKYTPKELLALLKYVEADIANYEVYLKEEVEKRKKYKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ | chromatin organization cranial skeletal system development negative regulation of DNA-templated transcription Notch signaling pathway protein deubiquitination protein K48-linked deubiquitination regulation of cell cycle regulation of cell growth ubiquitin-dependent protein catabolic process cytoplasm; nucleus; PR-DUB complex chromatin binding cysteine-type deubiquitinase activity Danio rerio Chromatin regulator Cytoplasm Hydrolase Nucleus Protease Reference proteome Thiol protease Ubl conjugation pathway MNKGWLELES MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQSPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDDDIVNDMFFAHQLIPNSCATHALLSVLLNCSGVELGMTLSRMKAFTKGFNPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKDRLFELDGLKAYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYESKLDILKRNRQIILEGLQQIREKKVIRMTQQESGQDRKQQDSSSSEDTPPVVKKEEVQETPIPSGAEQATPTEAQEGAASLPSPAGKVRSMAKPALPAGGAPPPAPLPAPSTNTIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRPPQPPYSDDEDDYDDEEEECSTAGVTNSRVRRKLGLRTRTMSRTAVGGVAAMEGQLALSVLAEKLKKEVQRKDALATTGSTPLNVRTEGRTGGISITSACQPSPTPSNESTDTASEIGSAFNSPLRSPARSQATTRPSSPVASHVGRVLFGEEEGLPRLDARHNRAVRDLGVLVSSTQLQLQEDGVIFALPPTEALEGLKKVGGVDKKKKEEASGPGGEEEVKEGPSVEMKAEDVKESVDVKPEKENLPTTDVENSTKPPGEKYTPKELLALLKYVEADIANYEVYLKEEVEKRKKYKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ |
adaptive immune response antibacterial innate immune response antigen processing and presentation of exogenous peptide antigen antigen processing and presentation of exogenous peptide antigen via MHC class I defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium dendritic cell antigen processing and presentation | cytoplasmic vesicle; endolysosome; phagocytic vesicle; phagocytic vesicle membrane; phagolysosome membrane | pore-forming activity wide pore channel activity | Mus musculus | 3D-structure Adaptive immunity Cytoplasmic vesicle Disulfide bond Glycoprotein Immunity Innate immunity Membrane Reference proteome Signal Transmembrane Transmembrane beta strand Transmembrane helix Ubl conjugation | MNSFMALVLI | MNSFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA | adaptive immune response antibacterial innate immune response antigen processing and presentation of exogenous peptide antigen antigen processing and presentation of exogenous peptide antigen via MHC class I defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium dendritic cell antigen processing and presentation cytoplasmic vesicle; endolysosome; phagocytic vesicle; phagocytic vesicle membrane; phagolysosome membrane pore-forming activity wide pore channel activity Mus musculus 3D-structure Adaptive immunity Cytoplasmic vesicle Disulfide bond Glycoprotein Immunity Innate immunity Membrane Reference proteome Signal Transmembrane Transmembrane beta strand Transmembrane helix Ubl conjugation MNSFMALVLI MNSFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA |
erythrocyte enucleation erythrocyte maturation eye development | nuclear envelope; nuclear inner membrane | protein self-association | Xenopus laevis | Developmental protein Membrane Nucleus Reference proteome Signal Transmembrane Transmembrane helix | MAGEVEGRGC | MAGEVEGRGCGFSLGVLVTLLVLPLPSLCTLSTEKELHVIKLYEGRMVRYNESRNFCYQRTYEPKWSDVWTKIQIRINSTKMIRVTQVDNEEKLKEMETFNMFDFFSSFLKEKLNDTFIYVNLYSNKTCVKVHLTDTDTYYSVALSRGFDPRLFFVFLCGLLLFFYGDTLSRSQLFFYSTGITVGMLASMLILVFMLSKLMPKKSPFFALLLGGWSVSIYVIQLVFRNLQAICSEYWQYLIVYLGIVGFVSFAFCYIYGPLENERSINILNWTLQLIGLLLMYVSVQIQHIAVTIVVIAFCTKQIEYPVQWIYILYRKIKLKRAKPGPPRLLTEEEYRKQADVETRKALEELRECCSSPDFAAWKTISRIQSPKRFADFVEGSSHLTPNEVSVHEHEYGLGGSFLEDELFGEDSDVEEEMEIEPPLYPIPRSVF | erythrocyte enucleation erythrocyte maturation eye development nuclear envelope; nuclear inner membrane protein self-association Xenopus laevis Developmental protein Membrane Nucleus Reference proteome Signal Transmembrane Transmembrane helix MAGEVEGRGC MAGEVEGRGCGFSLGVLVTLLVLPLPSLCTLSTEKELHVIKLYEGRMVRYNESRNFCYQRTYEPKWSDVWTKIQIRINSTKMIRVTQVDNEEKLKEMETFNMFDFFSSFLKEKLNDTFIYVNLYSNKTCVKVHLTDTDTYYSVALSRGFDPRLFFVFLCGLLLFFYGDTLSRSQLFFYSTGITVGMLASMLILVFMLSKLMPKKSPFFALLLGGWSVSIYVIQLVFRNLQAICSEYWQYLIVYLGIVGFVSFAFCYIYGPLENERSINILNWTLQLIGLLLMYVSVQIQHIAVTIVVIAFCTKQIEYPVQWIYILYRKIKLKRAKPGPPRLLTEEEYRKQADVETRKALEELRECCSSPDFAAWKTISRIQSPKRFADFVEGSSHLTPNEVSVHEHEYGLGGSFLEDELFGEDSDVEEEMEIEPPLYPIPRSVF |
axon extension brain-derived neurotrophic factor receptor signaling pathway dendrite extension dendritic spine development establishment of cell polarity neuron projection morphogenesis potassium ion transmembrane transport proton transmembrane transport regulation of intracellular pH regulation of neurotrophin TRK receptor signaling pathway regulation of postsynaptic membrane neurotransmitter receptor levels sodium ion import across plasma membrane synapse organization | axon terminus; axonal spine; cytoplasmic vesicle; dendrite; early endosome; early endosome membrane; endoplasmic reticulum membrane; endosome; glutamatergic synapse; intracellular membrane-bounded organelle; late endosome; late endosome membrane; mitochondrion; plasma membrane; recycling endosome; recycling endosome membrane; Schaffer collateral - CA1 synapse; synapse | identical protein binding potassium:proton antiporter activity sodium:proton antiporter activity | Mus musculus | Cell membrane Endosome Ion transport Membrane Reference proteome Sodium Sodium transport Transmembrane Transmembrane helix Transport Ubl conjugation | MAGARRGWRL | MAGARRGWRLAPVRRGVCGPRARPLMRPLWLLFAVSFFGWTGALDGSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYTLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFIAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPDNERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTESATASAPRRFMGNSSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA | axon extension brain-derived neurotrophic factor receptor signaling pathway dendrite extension dendritic spine development establishment of cell polarity neuron projection morphogenesis potassium ion transmembrane transport proton transmembrane transport regulation of intracellular pH regulation of neurotrophin TRK receptor signaling pathway regulation of postsynaptic membrane neurotransmitter receptor levels sodium ion import across plasma membrane synapse organization axon terminus; axonal spine; cytoplasmic vesicle; dendrite; early endosome; early endosome membrane; endoplasmic reticulum membrane; endosome; glutamatergic synapse; intracellular membrane-bounded organelle; late endosome; late endosome membrane; mitochondrion; plasma membrane; recycling endosome; recycling endosome membrane; Schaffer collateral - CA1 synapse; synapse identical protein binding potassium:proton antiporter activity sodium:proton antiporter activity Mus musculus Cell membrane Endosome Ion transport Membrane Reference proteome Sodium Sodium transport Transmembrane Transmembrane helix Transport Ubl conjugation MAGARRGWRL MAGARRGWRLAPVRRGVCGPRARPLMRPLWLLFAVSFFGWTGALDGSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYTLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFIAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPDNERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTESATASAPRRFMGNSSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA |
fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid long-chain fatty-acyl-CoA biosynthetic process sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process very long-chain fatty acid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane | fatty acid elongase activity | Homo sapiens | 3D-structure Acetylation Disulfide bond Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MAFSDLTSRT | MAFSDLTSRTVHLYDNWIKDADPRVEDWLLMSSPLPQTILLGFYVYFVTSLGPKLMENRKPFELKKAMITYNFFIVLFSVYMCYEFVMSGWGIGYSFRCDIVDYSRSPTALRMARTCWLYYFSKFIELLDTIFFVLRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHALLNTAVHVVMYSYYGLSALGPAYQKYLWWKKYLTSLQLVQFVIVAIHISQFFFMEDCKYQFPVFACIIMSYSFMFLLLFLHFWYRAYTKGQRLPKTVKNGTCKNKDN | fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid long-chain fatty-acyl-CoA biosynthetic process sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process very long-chain fatty acid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane fatty acid elongase activity Homo sapiens 3D-structure Acetylation Disulfide bond Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Reference proteome Transferase Transmembrane Transmembrane helix MAFSDLTSRT MAFSDLTSRTVHLYDNWIKDADPRVEDWLLMSSPLPQTILLGFYVYFVTSLGPKLMENRKPFELKKAMITYNFFIVLFSVYMCYEFVMSGWGIGYSFRCDIVDYSRSPTALRMARTCWLYYFSKFIELLDTIFFVLRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHALLNTAVHVVMYSYYGLSALGPAYQKYLWWKKYLTSLQLVQFVIVAIHISQFFFMEDCKYQFPVFACIIMSYSFMFLLLFLHFWYRAYTKGQRLPKTVKNGTCKNKDN |
fatty acid beta-oxidation | fatty acid beta-oxidation multienzyme complex | 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding | Shewanella amazonensis | Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase Reference proteome | MIYQSPTIQV | MIYQSPTIQVELTADKIARLCFNAPGSVNKFDRETLASLNAALDVLKDSDAKAAVLTSGKDTFIVGADITEFLALFAEEDAKLMEWIAQANVVFNKLEDLPFPTVSAIKGFALGGGCEAILATDFRVADTSAKIGLPETKLGLIPGFGGTVRLPRLIGADNALEWITTGKDQRPEDALKVGAIDAVVAPENLEAAAIQMLNDALAGKLDWQARRARKQAPLTLPKLEAMMSFTTAKGMVYAVAGKHYPAPMAAVSVVEQAAGMSRAEALVVEHNAFIKLAKTDVATALIGIFLNDQLVKGKAKKASKLAKDIKHAAVLGAGIMGGGIAYQSASKGTPIVMKDINQAALDLGVNEAAKLLSAQVARGRSTPDKMAKVLNNITPALDYAPLKDVNVVVEAVVENPKVKAMVLADVENVVADDAIIASNTSTISIDLLAKSLKNPARFCGMHFFNPVHKMPLVEVIRGKDTSEETVASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLADGGDFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMADGFPDRMGKSDKDAIDVMYEAGRLGQKNGKGFYQYSIDKRGKPKKDVDPASYTMLAEAFGAQKAFEADEIIARTMIPMIIETVRCLEEGIVASPAEADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYAHLGGLYQVTDAMRELASNNGSYYPKA | fatty acid beta-oxidation fatty acid beta-oxidation multienzyme complex 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxybutyryl-CoA epimerase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity NAD+ binding Shewanella amazonensis Fatty acid metabolism Isomerase Lipid degradation Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase Reference proteome MIYQSPTIQV MIYQSPTIQVELTADKIARLCFNAPGSVNKFDRETLASLNAALDVLKDSDAKAAVLTSGKDTFIVGADITEFLALFAEEDAKLMEWIAQANVVFNKLEDLPFPTVSAIKGFALGGGCEAILATDFRVADTSAKIGLPETKLGLIPGFGGTVRLPRLIGADNALEWITTGKDQRPEDALKVGAIDAVVAPENLEAAAIQMLNDALAGKLDWQARRARKQAPLTLPKLEAMMSFTTAKGMVYAVAGKHYPAPMAAVSVVEQAAGMSRAEALVVEHNAFIKLAKTDVATALIGIFLNDQLVKGKAKKASKLAKDIKHAAVLGAGIMGGGIAYQSASKGTPIVMKDINQAALDLGVNEAAKLLSAQVARGRSTPDKMAKVLNNITPALDYAPLKDVNVVVEAVVENPKVKAMVLADVENVVADDAIIASNTSTISIDLLAKSLKNPARFCGMHFFNPVHKMPLVEVIRGKDTSEETVASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLADGGDFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMADGFPDRMGKSDKDAIDVMYEAGRLGQKNGKGFYQYSIDKRGKPKKDVDPASYTMLAEAFGAQKAFEADEIIARTMIPMIIETVRCLEEGIVASPAEADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYAHLGGLYQVTDAMRELASNNGSYYPKA |
adipose tissue development bone development cell differentiation extracellular matrix disassembly eye development heart development podosome assembly protein localization to membrane skeletal system development superoxide anion generation superoxide metabolic process | anchoring junction; cell projection; cytoplasm; podosome | phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3-phosphate binding phosphatidylinositol-5-phosphate binding SH2 domain binding superoxide-generating NADPH oxidase activator activity | Homo sapiens | Cell junction Cell projection Cytoplasm Differentiation Disease variant Phosphoprotein Reference proteome Repeat SH3 domain | MPPRRSIVEV | MPPRRSIVEVKVLDVQKRRVPNKHYVYIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNPPKEEHIGKKKSGGDQTSVDPMVLEQYVVVANYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKPGPGSPSHPGALDLDGVSRQQNAVGREKELLSSQRDGRFEGRPVPDGDAKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDKYKKTSNASRPNFLAPLPHEVTQLRLGEAAALENNTGSEATGPSRPLPDAPHGVMDSGLPWSKDWKGSKDVLRKASSDMSASAGYEEISDPDMEEKPSLPPRKESIIKSEGELLERERERQRTEQLRGPTPKPPGVILPMMPAKHIPPARDSRRPEPKPDKSRLFQLKNDMGLECGHKVLAKEVKKPNLRPISKSKTDLPEEKPDATPQNPFLKSRPQVRPKPAPSPKTEPPQGEDQVDICNLRSKLRPAKSQDKSLLDGEGPQAVGGQDVAFSRSFLPGEGPGRAQDRTGKQDGLSPKEISCRAPPRPAKTTDPVSKSVPVPLQEAPQQRPVVPPRRPPPPKKTSSSSRPLPEVRGPQCEGHESRAAPTPGRALLVPPKAKPFLSNSLGGQDDTRGKGSLGPWGTGKIGENREKAAAASVPNADGLKDSLYVAVADFEGDKDTSSFQEGTVFEVREKNSSGWWFCQVLSGAPSWEGWIPSNYLRKKP | adipose tissue development bone development cell differentiation extracellular matrix disassembly eye development heart development podosome assembly protein localization to membrane skeletal system development superoxide anion generation superoxide metabolic process anchoring junction; cell projection; cytoplasm; podosome phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3-phosphate binding phosphatidylinositol-5-phosphate binding SH2 domain binding superoxide-generating NADPH oxidase activator activity Homo sapiens Cell junction Cell projection Cytoplasm Differentiation Disease variant Phosphoprotein Reference proteome Repeat SH3 domain MPPRRSIVEV MPPRRSIVEVKVLDVQKRRVPNKHYVYIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNPPKEEHIGKKKSGGDQTSVDPMVLEQYVVVANYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKPGPGSPSHPGALDLDGVSRQQNAVGREKELLSSQRDGRFEGRPVPDGDAKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDKYKKTSNASRPNFLAPLPHEVTQLRLGEAAALENNTGSEATGPSRPLPDAPHGVMDSGLPWSKDWKGSKDVLRKASSDMSASAGYEEISDPDMEEKPSLPPRKESIIKSEGELLERERERQRTEQLRGPTPKPPGVILPMMPAKHIPPARDSRRPEPKPDKSRLFQLKNDMGLECGHKVLAKEVKKPNLRPISKSKTDLPEEKPDATPQNPFLKSRPQVRPKPAPSPKTEPPQGEDQVDICNLRSKLRPAKSQDKSLLDGEGPQAVGGQDVAFSRSFLPGEGPGRAQDRTGKQDGLSPKEISCRAPPRPAKTTDPVSKSVPVPLQEAPQQRPVVPPRRPPPPKKTSSSSRPLPEVRGPQCEGHESRAAPTPGRALLVPPKAKPFLSNSLGGQDDTRGKGSLGPWGTGKIGENREKAAAASVPNADGLKDSLYVAVADFEGDKDTSSFQEGTVFEVREKNSSGWWFCQVLSGAPSWEGWIPSNYLRKKP |
Subsets and Splits