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Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+. [EC:1.4.1.1] | null |
Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+. [EC:1.4.1.1] | null |
Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+. [EC:1.4.1.1] | null |
Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+. [EC:1.4.1.1] | null |
Binding to a magnesium (Mg) ion. [GOC:ai] | null |
Binding to a magnesium (Mg) ion. [GOC:ai] | null |
The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing. [GOC:mah] | null |
The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing. [GOC:mah] | null |
The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing. [GOC:mah] | null |
The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing. [GOC:mah] | null |
A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends. [PMID:14729943] | null |
A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends. [PMID:14729943] | null |
Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues. [EC:3.6.1.10] | null |
Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues. [EC:3.6.1.10] | null |
Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues. [EC:3.6.1.10] | null |
Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues. [EC:3.6.1.10] | null |
Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues. [EC:3.6.1.10] | null |
Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm. [GOC:krc] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. [EC:2.7.7.1] | null |
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. [RHEA:10800] | null |
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. [RHEA:10800] | null |
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. [RHEA:10800] | null |
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. [RHEA:10800] | null |
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. [RHEA:10800] | null |
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. [RHEA:10800] | null |
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. [RHEA:10800] | null |
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. [RHEA:10800] | null |
Enables the transfer of sulfite ions from one side of a membrane to the other. [GOC:as] | null |
The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae. [GOC:krc, GOC:mtg_sensu] | null |
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. [GOC:krc, GOC:mtg_sensu] | null |
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. [GOC:krc, GOC:mtg_sensu] | null |
Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA. [PMID:11812242, PMID:7958872] | null |
Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA. [PMID:11812242, PMID:7958872] | null |
The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. [GOC:BHF-UCL, PMID:11884619, PMID:1808260] | null |
Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+. [EC:1.13.11.6, RHEA:17953] | null |
Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+. [EC:1.13.11.6, RHEA:17953] | null |
Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+. [EC:1.13.11.6, RHEA:17953] | null |
Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+. [EC:1.13.11.6, RHEA:17953] | null |
Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+. [EC:1.13.11.6, RHEA:17953] | null |
Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+. [EC:1.13.11.6, RHEA:17953] | null |
Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II. [GOC:krc] | null |
Binding to the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans. [GOC:krc] | null |
A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex. [PMID:10946105] | null |
A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation. [PMID:10946105] | null |
Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. [GOC:krc, ISBN:0879695897] | null |
Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. [GOC:krc, ISBN:0879695897] | null |
Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. [GOC:krc, ISBN:0879695897] | null |
Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. [GOC:krc, ISBN:0879695897] | null |
Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. [GOC:krc, ISBN:0879695897] | null |
Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. [GOC:krc, ISBN:0879695897] | null |
Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. [GOC:krc, ISBN:0879695897] | null |
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. [GOC:krc, ISBN:0879695897] | null |
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. [GOC:krc, ISBN:0879695897] | null |
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. [GOC:krc, ISBN:0879695897] | null |
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. [GOC:krc, ISBN:0879695897] | null |
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. [GOC:krc, ISBN:0879695897] | null |
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. [GOC:krc, ISBN:0879695897] | null |
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. [GOC:krc, ISBN:0879695897] | null |
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. [GOC:krc, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. [GOC:krc, GOC:mtg_mpo, ISBN:0879695897] | null |
The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing. [GOC:krc, PMID:11726664, PMID:12110900] | null |
The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing. [GOC:krc, PMID:11726664, PMID:12110900] | null |
The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize). [GOC:krc, PMID:11377794] | null |
The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. [GOC:krc, PMID:11377794] | null |
The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved. [GOC:krc, PMID:11377794] | null |
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs. [GOC:krc] | null |
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs. [GOC:krc] | null |
Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon. [GOC:krc, ISBN:0879695897, PMID:19239890] | null |
Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. [GOC:krc, ISBN:0879695897, PMID:19239890] | null |
Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. [GOC:krc, ISBN:0879695897, PMID:19239890] | null |
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). [GOC:krc, ISBN:0879695897] | null |
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). [GOC:krc, ISBN:0879695897] | null |
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). [GOC:krc, ISBN:0879695897] | null |
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). [GOC:krc, ISBN:0879695897] | null |
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). [GOC:krc, ISBN:0879695897] | null |
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). [GOC:krc, ISBN:0879695897] | null |
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). [GOC:krc, ISBN:0879695897] | null |
Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure. [GOC:krc, ISBN:0879695897] | null |
Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure. [GOC:krc, ISBN:0879695897] | null |
Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure. [GOC:krc, ISBN:0879695897] | null |
Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure. [GOC:krc, ISBN:0879695897] | null |