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Patients with TSHoma-associated autoimmune thyroiditis should undergo careful follow-up for development of Graves' disease after treatment.
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Two manic-depressive patients are described who presented with acute renal failure and concurrent lithium toxicity.
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The prognosis is generally poor for patients who experience a cardiac arrest.
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A patient with sinuatrial disease and implanted pacemaker was treated with amiodarone (maximum dose 1000 mg, maintenance dose 800 mg daily) for 10 months, for control of supraventricular tachyarrhythmias.
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As the prevalence of human immunodeficiency virus (HIV) infection continues to rise the clinician is encountered with a diagnostic challenge.
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Pleuropulmonary fibrosis after long-term treatment with the dopamine agonist pergolide for Parkinson Disease.
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Gabapentin may act directly upon temperature regulatory centers.
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We report the case of a 30-year-old male after kidney transplantation, treated with steroids, cyclosporin A and SRL, with steroid-resistant acute rejection in anamnesis.
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Periodic alternating nystagmus generally implies structural brainstem disease, especially at the craniocervical junction.
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The chemotherapeutics, including vincristine, actinomycin D, and epirubicin in case 1 and vincristine and actinomycin D in case 2, were given before the hepatotoxicity developed.
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We describe two cases of sulfadiazine-induced crystalluria and renal failure in patients with acquired immunodeficiency syndrome, review the pertinent literature, and discuss the pathogenesis.
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This case demonstrates that both epoetin alfa and darbepoetin alfa may artificially lower A1C levels in a patient with diabetes who is not undergoing dialysis, and therefore this finding can be interpreted as a class effect.
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Homozygosity for the methylentetrahydrofolate reductase (MTHFR) C677T polymorphism diagnosed by molecular genetic analysis was the only explanation for this toxicity.
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Six days after starting acyclovir she exhibited signs of lithium toxicity.
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Corticosteroids may be useful for therapy of some features of this syndrome, such as thrombocytopenia.
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Following treatment, that behavior also ceased.
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The other evaluable patients showed stable disease with improved symptoms.
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An adult female with developmental disability was prescribed chlorpromazine for the target behaviors of aggression and self-injurious behavior (SIB), and she was prescribed phenobarbital for seizures.
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Polyarthritis, hepatitis and anti-native DNA antibodies after treatment with ethambutol and rifampicin.
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Adenosine is used as pharmacological treatment of the first choice for the termination of regular small complex tachycardia.
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Chest roentgenogram showed interstitial congestive failure, and an EKG demonstrated sinus bradycardia.
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However, these drugs have different toxicity profiles and may have clinically relevant differences in immunosuppressive activity in individual patients.
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Respiratory effects of halothane in a patient with refractory status asthmaticus.
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A 48-year-old woman with a diagnosis of breast carcinoma was treated with adjuvant chemotherapy through a central venous catheter with subcutaneous reservoir (Port-A-Cath).
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Chronic traumatic trigeminal neuralgia.
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Bleeding occurred into the gastrointestinal tract in four patients, into the kidney-urinary tract in three patients, into vascular surgical sites in two patients, and one each into the pulmonary-bronchial and cerebral-ventricular systems.
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It is too early to evaluate four patients at present.
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The lesions were determined to be a phaeohyphomycosis, caused by Curvularia lunata.
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On the 3rd day, an inferior vena cava (IVC) filter was placed with a heparin flush, after which massive IVC thrombosis developed.
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Herbal product use in a patient with polypharmacy.
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Twenty days after cessation, cortisol concentrations were undetectable again.
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CONCLUSION: Overnight wearing of a rigid contact lens is a risk factor for a corneal ulcer.
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At 4-y follow-up, her condition is good.
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Successful treatment of bronchiolitis obliterans organizing pneumonia with low-dose methotrexate in a patient with Hodgkin's disease.
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A 28 year-old man with chronic hepatitis B was administered interferon-alpha (5 x 10(6) IU) intramuscularly once a day for 28 days.
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We describe a patient with acute leukemia who developed Horner's syndrome and a severe demyelinating peripheral neuropathy leading to death after receiving high-dose cytosine arabinoside.
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A computed tomography scan revealed a large mass, 12 cm x 7 cm, involving the scalp extending from the right temporal region to the vertex.
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The patient's mental status returned to baseline after treatment with intravenous phenytoin and discontinuation of ifosfamide therapy.
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Potential mechanisms regarding the pathophysiology of lithium-associated CDI are discussed.
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The potential autoimmune complications of this therapeutic agent should be comprehended when monitoring patients receiving such treatment.
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In renal transplant recipients it has previously been related to immunosuppressive treatment with cyclosporine.
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A year later, the patient reported complete disappearance of pain and swelling, although right breast continued to appear larger than the left.
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Immunoelectron microscopy of perilesional skin revealed IgA deposits within the lamina lucida and immunoblotting of the patient's serum disclosed IgA and IgG antibodies directed against epidermal antigens of 280, 165 and 120-130 kD.
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A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.
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This prompted a study of the effect of an eight week course of haloperidol (HAL) followed by two week withdrawal, on dopaminergic neurons of the substantia nigra in rats.
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Three years later, treatment with ampicillin caused another episode of cholestatic hepatitis with cholestasis and duct paucity on rebiopsy.
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The effect of oral dissolution therapy for pancreatic stones was evaluated in patients with chronic calcific pancreatitis.
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Three patients, in whom tumour overkill by cytotoxic treatment, including high dose methotrexate with folinic acid rescue, resulted in the 'phosphate shower syndrome' (hyper-uricaemia, hyperkalaemia and hyperphosphataemia with hypocalcaemia and tetany, with metabolic acidosis and acute renal impairment) are described.
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The respiratory effects of morphine and the particular risks posed to the elderly patient are discussed.
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This is the earliest onset PCP in the literature after HSCT despite the prophylactic administration of TMP/SMX before transplant.
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We describe the clinical course, renal function, serial renal histology and urine and blood viral load measurements in two consecutive patients with refractory BKVN who were treated with low-dose cidofovir (0.25 mg/kg IV).
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Hepatotoxicity of paracetamol enhanced by ingestion of alcohol: report of two cases.
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However, the pathogenesis of this association is not fully understood.
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Pneumocystis carinii (P. carinii) is one of the major opportunistic pathogens responsible for hematopoietic stem cell transplantation (HSCT)-related pneumonias.
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In the second block of the consolidation phase, 10 hours after triple intrathecal treatment, we realized that instead of 12 mg, 120 mg of methotrexate had accidentally been given.
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The patient presented with widespread medial calcification involving various small to medium sized arteries, although no noticeable secondary hyperparathyroidism was observed.
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Two patients had a poor outcome, 1 patient suffered a significant groin hematoma, and there were no instances of symptomatic intracerebral hemorrhage.
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Reported cases include probable pulmonary TB (1), pneumocystis pneumonia (1), other pulmonary infection (2), and septicemia (3) including a case of infective endocarditis.
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Lithium interferes with reserpine-induced dopamine depletion.
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Treatment with infliximab is known to produce an increase of autoantibodies (antinuclear antibodies, anti-double-stranded DNA), but not clinical disease.
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Patients were treated at a healthcare facility in 160 cases, with 79 patients admitted.
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Infracardiac total anomalous pulmonary venous connexion and unilateral renal agenesis with ipsilateral phocomelia and unicornuate uterus were associated anomalies.
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Despite their effectiveness, anti-TNF drugs have some drawbacks such as severe adverse effects including infections and possibly lymphoproliferative disorders.
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Phototesting with artificial light sources did not have any effect on the DSP lesions.
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Polymyositis, however, has never been reported immediately after treatment for active hyperthyroidism.
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Recognizing early signs of HMSN, such as areflexia and pes cavus deformity, can prevent severe neurotoxicity of polychemotherapy by avoiding vincristine.
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This observation suggests that long-term solvent exposure may trigger MF and hasten its progression from the patch stage to the plaque and tumour stages.
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The etiology of neurotoxicity in our two patients remains unclear; however, as CAP is rapidly metabolized to 5-FU in patients with normal liver function, it is likely that 5-FU or its active metabolites (fluoro-beta-alanine) were contributing factors.
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Regular surveillance of the patient detected a 3.5 cm HCC lesion.
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BACKGROUND: An osteogenic sarcoma of the skull is rare, particularly as a primary tumor.
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Ganciclovir is a nucleotide-analogue similar to acyclovir, which has an in vitro activity against herpes simplex type 1, herpes simplex type 2 and varicella zoster virus.
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A review of the literature found 11 children and 2 adults in whom intranasal desmopressin was associated with hyponatremia, all of whom experienced seizures or altered mental status.
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METHODS: A 70-year-old woman with bilateral normal tension glaucoma was treated with topical brimonidine and followed in an outpatient setting.
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CASE REPORT: A 47-year-old woman presented with a spontaneous sternal fracture, precluding effective coughing.
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Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.
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DISCUSSION: As of February 11, 2004, this is the first case, to our knowledge, to describe the use of oral terbutaline therapy for chronotropic support in the setting of acute rejection after heart transplantation.
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Neuroleptic malignant syndrome and severe thrombocytopenia: case report and literature review.
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The case concerns the sudden death of a 29-year-old male during clozapine therapy started 2 weeks before.
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Two infants developed hyperkalemia shortly after cessation of prolonged ACTH therapy for infantile spasms.
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From these findings, we determined his transfusion-resistant cytopenias to be attributable to HPS.
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The patient's hemoglobin decreased from 12.7 to 8.5 g/dL and he received a 3-unit blood transfusion.
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Ishihara color plates showed normal color vision.
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The stimulation indices of the drug-induced lymphocyte stimulation test (DLST) for AZA in these two patients were as high as 2,180% and 430%, respectively, but those of healthy volunteers were under 120% without nonspecific suppression of lymphocyte proliferation.
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Three senile patients developed fatal acute encephalopathy while receiving calcium hopantenate.
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We report the use of pharmacokinetic analysis of daptomycin in a 13-year-old boy with vancomycin-resistant Enterococcus faecium endocarditis.
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Magnetic resonance spectroscopy in Niemann-Pick disease type C: correlation with diagnosis and clinical response to cholestyramine and lovastatin.
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Currently the use of zidovudine is one of the few specific measures available, and as a potentially teratogenic and fetotoxic agent, any decision for its use requires evaluation of the potential for fetal damage.
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The pathogenesis, through retrograde spread of superficial infection to durocortical veins, is discussed in the light of serial CT scans at different stages of formation and treatment of the abscess.
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Hyponatraemia during low-dose carbamazepine therapy.
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Furosemide, spironolactone, hydroxyurea, allopurinol, and docusate were all reintroduced without reactivation of the lesions.
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Pulmonary capillaritis has been described in adult lung transplant recipients, but has not been previously reported in pediatric recipients.
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Acute cervico-facial oedema and loss of consciousness following ingestion of barracuda fish.
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The manual intravenous push has a greater possibility of inadvertent overdosage during some small time frame, as well as more local symptoms by some reports.
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First-trimester pregnancy exposure can cause major birth defects.
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Ulcerating enteritis associated with flucytosine therapy.
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MATERIAL AND METHODS: A 39-year-old male with idiopathic sudden SNHL that was responsive to corticosteroids was treated with ciclosporin for 18 months.
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Three years later, she complained of mild visual loss in the right eye.
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A 58-year-old woman developed unilateral acute angle-closure glaucoma four days after the application of a patch of transdermal scopolamine delivery system (TRANSDERM-V).
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Cytogenetic studies revealed an abnormal karyotype with deletion of the long arm of chromosome 11 (11q21) and 2 additional copies of the MLL gene attached to the short arms of chromosome 10 in 80% of the metaphase cells examined.
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This case demonstrates that TZDs may precipitate weight gain and pulmonary and peripheral edema in patients with stable heart failure.
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