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Physicians should be aware of this possible association because the signs and symptoms of Sweet's syndrome are easily mistaken as being due to infection.
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Two patients with ovarian carcinoma developed acute erythroleukemia following prolonged chemotherapy with an alkylating agent.
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Overall, the prevalence of patients lacking both lipodystrophy and serum lipid abnormalities was markedly higher for the cases than for the controls (69.5 vs. 13%, P<0.001).
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We conclude that the currently available data do not indicate that thrombolysis contributes to a significant increase in bleeding complications when administered during CPR.
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The second patient developed similar symptoms on day 3 of treatment with 2500 mg/m2.
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Skin biopsy revealed multiple superficial thrombosed vessels with focal epidermal necrosis as well as prominent interstitial mucinosis.
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In the third patient akathisia was sufficiently controlled by dose reduction.
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Paroxysmal supraventricular tachycardia during treatment with cisplatin and etoposide combination.
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Although her seizures stopped, her blood pressure fluctuated between 90/60 mm Hg and 60/30 mm Hg over the next several hours, requiring treatment with intravenous fluids and pressor therapy.
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In both, metoprolol produced objective and subjective improvement of the tremor without producing bronchospasm.
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Discontinuation of simvastatin and cyclosporine resulted in resolution of rhabdomyolysis and normalization of renal function.
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Isonicotinic acid hydrazide induced anagen effluvium and associated lichenoid eruption.
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The nystagmus resolved as the serum phenytoin level fell, as demonstrated by electronystagmography.
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The manufacturer began a Pregnancy Prevention Program (PPP) in 1988; however, exposed pregnancies continue to occur.
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Complications appear to result from depletion of plasma proteins involved in coagulation and fibrinolysis.
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Serum samples from the first and second days contained 3.6 and 1.9 mg/l carbachol, respectively.
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We discuss about the hypothesis that GHD may be related to chemotherapy and we report a review of previous published cases.
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IFN-alpha therapy (5 million U/day) was administered for 6 months longer.
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The patient's WBC count recovered within 4 days after the change in therapy.
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One of the postulated mechanisms of action is the release of endogenous opioids and/or the stimulation of opioid receptors in the central nervous system (CNS).
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We report a case of carcinoma following 42 years of chronic empyema in a patient who underwent surgery for a hydatid cyst at the age of 3.
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A 32-year-old male schizophrenic patient on ziprasidone treatment was admitted to the hospital following a seizure.
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CASE REPORT: A 52-year-old woman presented with an extensive flare of psoriasis associated with joint pain, especially in her knees and elbows.
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A symmetric elevation of diaphragms was shown on radiography and fluoroscopy.
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We report a case of reversible DKA and new-onset DM that developed in a demented patient who was treated with quetiapine for 14 days.
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Chemotherapy may be reserved for patients with positive cerebrospinal fluid, extracranial disease, or subsequent relapse.
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To our knowledge, t(4;11)(p12;q23) has been reported in two previous patients, and MLL and FRYL rearrangement was demonstrated in one of them.
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Immune reconstitution inflammatory syndrome should be considered in the differential diagnosis of unexplained vulval ulceration that arises after starting HAART.
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These symptoms worsened within a few days of an increase in the dose of fluvoxamine to 50 mg twice daily.
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The authors report the case of a 61-year-old man with CML treated with imatinib with a good response, and they switched to dasatinib after grade 4 hepatic toxicity.
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It is the most prescribed antineoplastic drug in the world, with approximately 10 million women-use-years of experience.
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Hyperthyroidism may exacerbate asthma.
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These findings are consistent with a model suggesting that both platelet and megakaryocyte mass contribute to a receptor-dependent consumption process regulating the endogenous TPO level.
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High dose methotrexate would appear contra-indicated in situations where massive tumour lysis is possible.
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Anaphylaxis to cisplatin is an infrequent life-threatening complication which may occur even in patients who have received prior treatment with cisplatin.
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Calciphylaxis in a patient with end-stage renal disease secondary to systemic lupus erythematosus associated with acral gangrene and mesenteric ischemia.
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Videopolysomnographic and pharmacokinetic studies with monitoring of plasma levodopa levels demonstrated marked motor hyperactivity during augmentation, with anarchic discharges of motor unit potentials, tonic grouped discharges and flexor spasms, associated with painful dysesthesia.
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MR images revealed extensive cortical and subcortical white matter brain edema.
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Recombinant human growth hormone (rhGH) therapy in Prader-Willi syndrome (PWS) causes increased basal metabolic rate and oxygen consumption, and hence increased ventilatory load.
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In addition to its known effect on gallbladder stasis, octreotide alters bile acid composition and may thus hasten intrahepatic sludge and stone formation.
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This is the second case of progressive multifocal leukoencephalopathy in a myasthenic patient.
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Its occurrence in diabetic children has not been previously reported.
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The mechanism of this effect is not entirely clear, but 5-azacytidine produces hypomethylation of the gamma gene at certain sites, and gene expression and DNA hypomethylation are related phenomena in many other systems.
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We report two cases of tenofovir (TDF)-associated nephrotoxicity in perinatally HIV-infected adolescents.
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Amikacin-induced type 5 Bartter-like syndrome with severe hypocalcemia.
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In an elderly patient with unresolving acute bronchospasm, herpesvirus infection of the lower respiratory tract should be considered in the differential diagnosis.
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The adequacy of corticosteroid replacement therapy may best be assessed by monitoring the levels of ACTH.
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Within four weeks after initiation of chemotherapy, the International Normalization Ratio (INR) increased from 3.04 to 39.56.
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The patient's visual acuity was 6/20 (non-corrected) in the right eye and 6/10 (-1.75/-1.00 x 91) in the left.
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CONCLUSIONS: The optimal anticoagulant for use in a patient with HIT and concurrent hepatic and renal failure is unclear.
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In summary, because infected grafts can lead to serious complications, besides careful donor screening, it is important to achieve early recognition of contaminated organs by culturing the perfusate to start specific antibiotic or antifungal therapy after transplantation if necessary and avoid the rare but, in this case, fatal consequences of these infections.
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Severe respiratory syncytial virus pulmonary infection in a patient treated with fludarabine for chronic lymphocytic leukemia.
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Plasma cryofibrinogen was measured before and during treatment with stanozolol.
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Four months later reversible camptocormia was manifested again concomitantly with about the same plasma valproate levels as above.
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The patient had removed the hair from her axillae with wax 3 weeks before the development of the eruption.
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Since its release in the United States market in 1996, few cases of fatal acute intoxication have been reported in the literature.
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Pediatric clonidine intoxications.
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Cyanoacrylate glue for type iii lad perforation.
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This article describes two cases of aplastic anemia, at least one of which was almost certainly induced by the use of methazolamide, and one case of agranulocytosis related to the use of methazolamide.
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The management of this clinical challenge is reviewed, in the absence of a clinical guideline, with particular reference to the judicious tailoring of anti-platelet therapy, the role of therapeutic endoscopy and the utility of blood transfusion.
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Successful treatment of postoperative pyoderma gangrenosum with cyclosporin.
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Moreover, in the appropriate clinical setting, even in the absence of pulmonary signs or symptoms, diffuse pulmonary uptake of labeled leukocytes should alert the physician to the possibility of drug-induced pneumonitis.
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Clinicians should consider early diagnostic amniocentesis in patients in preterm labor with a history of prior amniocentesis, and the routine Gram stain and culture of amniotic fluid.
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White, flocculent material was observed in the anterior chamber and 24 hours later this settled on the iris surface.
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Preoperative chemotherapy with carboplatin alone in high risk medulloblastoma.
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Drug-induced gingival enlargement has been reported in patients treated with various types of anticonvulsant drugs, and is generally associated with the presence of plaque, gingival inflammation, and a genetic predisposition.
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Although it is generally well tolerated, 30 to 45% of patients may experience adverse cardiac effects.
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This fourth type of cutaneous minocycline hyperpigmentation may be a variant of Type I, but based on clinical, pathological and microanalytical differences, appears to be a new entity.
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A case report and review of the literature.
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Renal function returned to normal eventually, but she continued to have relapses of exfoliative dermatitis up to a year later.
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Two years later myasthenia gravis appeared.
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The patient achieving a partial response experienced no side effects while receiving ipilimumab.
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Once the diagnosis was made, he was treated with adrenaline and made a full recovery.
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We report a patient in whom the anti-depressant trazodone hydrochloride (Molipaxin, Roussel), a serotonin antagonist, provoked generalized pustular psoriasis (GPP).
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Laboratory studies revealed a white blood cell count of 4900 mm(-3) with 67% neutrophils and 27% lymphocytes.
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Abdominal CT showed diffuse swelling of the pancreas, with two distinct masses in the corpus and the tail.
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Bilateral inguinal scrofuloderma during steroid therapy in a patient with bullous pemphigoid.
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In some patients, clinical vigilance for antidepressant-induced dysphoria may be warranted for extended periods of time.
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Malignant lymphoma of skin associated with postmastectomy lymphedema.
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On the basis of the clinico-radiologic presentation, a pulmonary hemorrhage was likely to occur; so to clarify the origin of this process, a complete serologic examination was performed but all the antibodies were negative.
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The most commonly reported side effects include dry mouth and dysphagia.
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A patient developed papilloedema and hepatic dysfunction while being treated with perhexiline maleate.
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As a result, the Flexiflo Inverta percutaneous endoscopic gastrostomy tubes with externally removable internal bumpers were found useful in the treatment of buried bumper syndrome, and the buried bumper was easily removed by external traction without any endoscopic or surgical methods.
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Methylephedrine is generally harmless and is contained in many cough and cold preparations.
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During clarithromycin coadministration, four out of the seven patients developed moderate-to-severe toxic symptoms of carbamazepine, such as drowsiness, dizziness, and ataxia, which resolved within 5 days after clarithromycin discontinuation.
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Also, concomitant therapy with antianxiety medications that may mask the symptoms of electrolyte disorders should be undertaken with caution.
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Review of the literature leads us to propose the following hypotheses: (1) that considerably increased stress-induced cortisol concentrations in critically ill patients may contribute to adverse outcomes and (2) that therapeutic suppression of the persistent and substantially elevated glucocorticoid levels in selected cases may be a beneficial therapeutic option.
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The patient survives with severe sequela which confirms slow progression as typical in nonAIDS cases.
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DISCUSSION: The main adverse effects of leflunomide consist of diarrhea, nausea, liver enzyme elevation, hypertension, alopecia, and allergic skin reactions.
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Later, she began treatment with mirtazapine.
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The patient did not achieve remission despite intensive chemotherapy, and subsequently underwent UCBT with a standard conditioning regimen.
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Nephrotic patients in endemic areas of Strongyloides infection should have the differential white cell count checked.
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We describe a 58-year-old female patient with end-stage renal disease who 7 years after the onset of dialysis presented with pain and movement restriction of various joints.
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On December 5, 1995, he began therapy with recombinant IFN-alpha at a dose of 3 MIU three times a week.
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Hepatotoxicity after high-dose methylprednisolone for demyelinating disease.
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This report describes two patients who developed acute myelocytic leukemia only after exposure to cyclophosphamide, methotrexate, and 5-fluorouracil adjuvant therapy.
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Once ARF is established, repair processes set in which appear to depend on growth factors such as epidermal growth factor and insulin-like growth factor 1, of which there is a relative shortage in established ARF.
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We also discuss the possible role of protein S deficiency as a contributing factor.
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We report a case in which ARB was given to the mother from the first trimester until 26 weeks' gestation.
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A 66-year-old Japanese woman with severe scleroderma developed anemia and thrombocytopenia due to D-penicillamine (D-Pen) treatment, although the leukopenia was not markedly severe.
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