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Little is known regarding etiologic risk factors, optimal management, and prognosis.
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This article describes three cases that illustrate possible rationales for combination antidepressant therapy: reduced side effects, synergistic treatment effects, reduced treatment response time, prescriber familiarity, and clinical experience.
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Reported are three children who developed progressive paraparesis after intrathecal methotrexate administration followed by complete or partial recovery.
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A 31-year-old Black male with a history of hypertension, partial seizures, and schizophrenia developed acute rigidity closely followed by severe hyperpyrexia (temperature 102 degree F), tachypnea, and tachycardia.
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The other patient is also in remission and on maintenance treatment for leukemia.
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M. marinum was cultured from the lesions and also identified by PCR on formalin-fixed tissue.
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Prosthetic valve thrombosis is associated with high mortality.
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Leishmania infantum leishmaniasis in corticosteroid--treated patients.
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Based on these observations and data in the literature, they discuss a possible relationship.
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Danazol and multiple hepatic adenomas: peculiar clinical findings in an acromegalic patient.
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Genotyping of CYP2B6 and therapeutic drug monitoring in an HIV-infected patient with high efavirenz plasma concentrations and severe CNS side-effects.
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The patient had flowing ossification along thoracic spine resembling diffuse idiopathic skeletal hyperostosis (DISH), but there was no ligament calcification in the lumbar spine or pelvis.
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Para-aminosalicylic acid-induced hypoglycaemia in a patient with diabetic nephropathy.
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Jarisch-Herxheimer reaction.
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CASE SUMMARY: A 75-year-old white man received 23.6 grams of ofloxacin over a 51-day period for epididymitis.
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Azathioprine-induced myelosuppression due to thiopurine methyltransferase deficiency in a patient with autoimmune hepatitis.
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I also describe agents that are used to treat common problems in PD patients, including hallucinations, orthostasis, nausea, erectile dysfunction, depression, and memory loss.
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This profile should trigger a "red flag" as to the possibility of phenobarbital behavioral side effects or exacerbation of preexisting maladaptive behaviors.
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After several days of heparin therapy, the dialyzer circuit thrombosed and the platelet count decreased to 82 x 10(3)/mm(3).
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Oculomotor disturbances associated with 5-fluorouracil chemotherapy.
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Chemoradiation therapy used on pediatric oncology patients often causes dental developmental anomalies that affect future dental care.
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N. asteroides sepsis subsequently developed, leading to his death.
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A patient with Hodgkin's disease developed acute radiation pneumonia four months after completion of mantle radiotherapy and during cyclical adjuvant chemotherapy.
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This new approach may represent improved therapy and prevent the hazards of catheter exchange and systemic antibiotic therapy.
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An adolescent male developed acute pancreatitis and pseudocyst of the pancreas 16 weeks after cessation of intramuscular L-asparaginase.
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The benefit of antithymocyte globulin in severe aplastic anemia in the pediatric age group was assessed.
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Elevation of the blood lactate concentration by alkali therapy without requiring additional lactic acid accumulation: theoretical considerations.
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To date, there have been no recorded cases of lichenoid drug eruptions (LDEs) caused by clinical use of the nonsteroidal anti-inflammatory drug salsalate.
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The data substantiate previous findings in brain tissue from a patient with pyridoxine-dependent seizures.
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A heightened awareness of this possibility may therefore lead to recognition of more cases and further understanding of this entity.
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There are a few case reports on hair loss associated with tricyclic antidepressants and serotonin selective reuptake inhibitors (SSRIs), but none deal specifically with paroxetine.
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The patient remained hospitalized for 3 months.
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The case of a pregnant woman with a breast mass that proved to be a granulocytic sarcoma is presented.
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We conclude peripheral neuropathy with 5-FU is rare.
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INTRODUCTION: We describe the neurointensive care (NIC) management of a patient with severe cerebral swelling and raised intracranial pressure (ICP) after severe sodium valproic acid (VPA) intoxication.
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Both patients responded to intravenous administration of diazepam 10 mg and were given levetiracetam as maintenance therapy.
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Life-threatening hyperkalemia induced by arginine.
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Interaction between tacrolimus and nefazodone in a stable renal transplant recipient.
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Polyarthritis, hepatitis and anti-native DNA antibodies after treatment with ethambutol and rifampicin.
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He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil.
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The goals of treatment are mainly preventative, i.e., cessation of steroids as soon as possible and protective bracing of the remaining intact Achilles tendon.
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These findings suggest that the corneal and retinal changes are the result of a toxic effect of tamoxifen when used in the doses and duration described.
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CONCLUSION: The present findings suggest that: (i) amantadine probably exerts its anti-dyskinetic effect by acting on the "indirect" pathway; (ii) the pathophysiological mechanisms of subthalamotomy induced dyskinesias may differ from those involved in L-dopa induced dyskinesias; (iii) dyskinesias induced by STN surgery resolve spontaneously as compensatory mechanisms develop.
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This treatment has the potential to cause severe vision loss as a result of intractable corticosteroid-induced glaucoma.
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Drug-induced pericarditis mimicking Brugada syndrome.
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ADAMTS13 was normal in four patients and mildly decreased in two patients.
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A 67-year-old patient, with primary polymyositis and without previous evidence of liver disease, developed clinical and biochemical features of severe cholestasis 3 months after initiation of azathioprine therapy.
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Electroencephalography showed abnormalities of the type associated with metabolic disturbance.
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CLINICAL PRESENTATION: We report two cases with multiple sclerosis, who developed meningioma four and twenty years after the diagnosis of MS was made.
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The hyperglycemia once again resolved with discontinuation of the drug.
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The T4 (helper)/T8 (suppressor) ratio decreased (1.0 and 1.2) on two different days, although above the normal limit.
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In addition to the recognized arrhythmic complications, the authors emphasize myocardial necrosis as a possible further manifestation of amsacrine-related cardiotoxicity.
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Clinical course of macular edema in two cases of interferon-associated retinopathy observed by optical coherence tomography.
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OBJECTIVE: 1) To describe a patient with rheumatoid arthritis receiving adalimumab who developed fever, pancytopenia, splenomegaly, and extreme hyperferritinemia.
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Analgesia was not compromised by the use of donepezil, and in some cases it appeared improved.
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Amoxapine-induced cognitive impairment in two patients.
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CONCLUSIONS: Amphotericin B overdose can be fatal in children and infants.
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PCR analysis showed CMV-DNA in the failed graft.
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DISCUSSION: The causal association between anticoagulant therapy and spontaneous hemothorax remains relatively uncommon.
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Although they had only a few nodules at diagnosis, the nodules increased in number and size 3 to 4 months after the start of methotrexate therapy in both patients.
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Sweet's syndrome is an acute febrile neutrophilic dermatosis that is a known complication of the administration of filgrastim, a drug that causes increased neutrophil proliferation and differentiation.
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This hypofluorescence line enlarged over the time.
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Protease inhibitors (ritonavir and saquinavir) were added to the treatment and the patient developed progressive ataxia related to carbamazepine toxicity.
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G-CSF also enhanced expression of the transferrin receptor (CD71) on blast cells in vitro.
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PURPOSE: To describe the clinical and electrophysiological findings in a young boy with decreased vision possibly due to retinal damage by rifabutin.
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In the oncology patient, chemotherapy, corticosteroids and bone marrow transplantation (with associated preparation therapy) have all been implicated as possible causes.
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Because there have been no reports of endoscopic observations of bacterial ventriculitis, we were unable to be certain about the origin or significance of the microgranulations.
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We recently dealt with a case of severe OHS presenting features of liver dysfunction; such a case has not been reported on before.
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Although a rechallenge was not tried, this case appears to demonstrate a temporal relationship between the initiation and discontinuation of metoclopramide and the onset and resolution of symptoms.
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On day 7 of linezolid treatment, the patient developed severe pruritus, macular rash, facial edema, eosinophilia, marked increase in serum creatinine level, and mild hepatitis.
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We describe a case of a woman with subarachnoid haemorrhage who developed hypocalcaemia and decreased serum parathyroid hormone levels due to hypermagnesemia.
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A lupus-like syndrome associated with infliximab therapy.
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He was asymptomatic at presentation and physical examination was unremarkable.
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Cryptococcal infections are seen mainly in immunocompromised hosts.
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RESULTS: Three patients (one woman, two men) with a mean age of 76.3 years developed neovascularization at the L-CRA site and underwent treatment as described with a mean follow-up time of 7 months.
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PURPOSE: To report 4 cases of Toxoplasma gondii retinochoroiditis in patients having recently undergone cardiac transplantation.
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A reticular pattern on high resolution CT (HRCT) invariably represents significant lung pathology and is the dominant feature of irreversible fibrosis.
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One child did not achieve detectable concentrations on 2 different study days and was switched to a different protocol.
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Postdural puncture cerebral spinal fluid (CSF) leak most often manifests as a postdural puncture headache (PDPH).
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Alcohol withdrawal syndrome (AWS) is a major cause of morbidity and mortality in the acute care setting.
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Severe deterioration in cognitive function and personality in five patients with long-standing diabetes: a complication of diabetes or a consequence of treatment?
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Over the next several months, she continued to require supplemental calcium, magnesium, potassium, and phosphorus.
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Familial, dexamethasone-suppressible, normokalemic hyperaldosteronism.
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Postmortem examination showed leukemia infiltration of the liver and spleen.
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Combined central retinal artery and central retinal vein occlusion following pars plana vitrectomy.
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The patient developed unusually severe hematological toxicity to chemotherapy as compared to nonsmall cell lung cancer patients without the GD defect.
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METHOD: The Hospital case note of a 27 year old widow with HIV infection and anaemia, who has been on HAART (Zidovudine, Lamivudine and Nevirapine) for one year, was reviewed.
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This is the first report of a possible association between an acute cardiovascular event and venlafaxine.
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We report the case histories of two patients with histologically confirmed adenocarcinoma of the prostate, both of whom had been treated with steroidal anti-androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation, and who subsequently developed femoral head avascular necrosis.
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Our case shows that clinical symptoms of polymyositis improved with steroid and immunoglobulin treatment without deterioration of the hepatitis B.
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Drug induced liver injury secondary to interferon-beta (IFN-beta) in multiple sclerosis.
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When tuberculosis patients on isoniazid eat certain varieties of fish they may develop a histamine reaction.
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Myasthenic patients receiving ampicillin should be closely monitored for possible acute exacerbations.
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The latter case was diagnosed by needle aspiration of the cyst.
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MTX-induced hepatic injury and liver enzyme elevations have been demonstrated after treatment of leukemia, gestational disease and during treatment of psoriasis and rheumatoid arthritis.
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Following are two clinical case reports demonstrating profound cerebral edema associated with implantation of Gliadel wafers.
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This methodology provides the decision analyst with a procedure to evaluate the outcome of specification uncertainty, in many decision problems, without resorting to Monte Carlo analysis.
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The patient suffered from progressive anemia with the lowest hemoglobin level of 21 g/L.
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RESULTS: Steroid-dependent SNHL was confirmed on audiological evaluation.
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RESULTS: In a 22-year-old Thai woman with Graves' disease, tinnitus, hearing impairment in the left ear (with progression to the right ear), and vertigo developed after 3 years of therapy with PTU.
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