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Dose-intensive melphalan with blood stem cell support for the treatment of AL amyloidosis: one-year follow-up in five patients.
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Case report.
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We report the case of a patient who developed polyserositis (pericardial effusion, pleural effusion, and pericarditis) after being started on clozapine, and whose symptoms remitted upon discontinuation of clozapine.
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This case and other published evidence should alert physicians to the possibility of fatal erlotinib-induced ILD.
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Acute hemorrhagic gastritis associated with acetazolamide intoxication in a patient with chronic renal failure.
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Two patients received corticosteroids as well as parenteral nutrition during the course of their disease.
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Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine.
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However, five patients showed delayed 30-Hz flicker b waves, and seven patients showed delayed oscillatory potentials.
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Treatment with oral 25-hydroxyvitamin D3, 50 microgram daily, produced marked biochemical, radiological, and histological improvement after 6 months.
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Early postsplenectomy arthritis caused by penicillin-resistant Streptococcus pneumoniae.
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He had a history of treatment-resistant chronic schizophrenia.
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A 55-year-old woman received 2 cycles of therapy with cisplatin 100 mg/m2 without difficulty.
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If this patient would have died suddenly without the laboratory investigations that lead to the diagnosis of myeloblastic leukemia, the cause would have been probably and wrongfully allotted to treatment with olanzapine.
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Both patients had laboratory-proven subtherapeutic anticonvulsant serum levels.
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The patient was transferred to a rehabilitation center.
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10 and 15 exchanges of PD using an automated cycler were respectively performed during the first and second 24-hour periods after gadolinium exposure.
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She received no other concomitant medications.
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A case report with emphasis on medication and management.
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The first patient's KI67 level was 2.5% and was positive for the progesterone and estrogen receptor.
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Their hair grew back after 2-3 months steroid therapy.
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Infection and thromboembolic events are relatively frequent complications, but aneurysm formation is rare.
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Sciatic nerve compression very rarely occurs bilaterally.
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Instead of diverse antiretroviral therapies, the viral load was increased.
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All three patients likely experienced electromechanical dissociation (EMD).
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CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.
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D-penicillamine induced crescentic glomerulonephritis: report and review of the literature.
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An 18-year-old man with attention-deficit-hyperactivity disorder (ADHD) was prescribed varenicline for smoking cessation.
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Thrombotic thrombocytopenic purpura induced by trimethoprim-sulfamethoxazole in a Jehovah's Witness.
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Recently, some studies have also reported association between patients with juvenile rheumatoid arthritis (JRA) treated with Methotrexate (MTX) and malignant lymphoma developing.
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METHODS: Between 1990 and 2003, 218 patients underwent an all-polymethylmethacrylate, collar button-shaped KPro surgery.
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Patients with a history of previous coronary artery disease or risk factors for coronary artery disease should be observed closely for signs of myocardial ischemia, particularly during the initial infusion.
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Possible causal mechanisms are discussed.
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RESULTS: Nine patients were cured, one patient with poor adherence to treatment and advanced AIDS died.
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Serious lead poisoning in childhood: still a problem after a century.
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BACKGROUND: Colchicine has a known adverse effect on wound healing through its inhibitory effect on tubulin-dependent cell functions and through collagenase activation.
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No dose-rate effect has been reported, however.
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Other toxicities were generally mild.
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The aim of this study was to determine the usefulness of skin tests in ruling out cross-reaction to cisplatin to continue platinum-based chemotherapy in patients who are responsive to these agents.
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One month later the patient remained symptom-free.
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Histochemistry identified a calcium containing melanin-like substance.
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Corynebacterium striatum has rarely been reported to be a pathogen, causing pleuropulmonary infections and bacteremia in only immunocompromised or anatomically altered patients.
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However, all Brown Norway rats that received estradiol treatment developed pyometra, whereas none the Sprague Dawley or control Brown Norway rats did.
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Necrotizing fasciitis secondary to bisphosphonate-induced osteonecrosis of the jaw.
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While more studies are needed to better understand the mechanism of action after suspending HAART, the complete resolution of the signs and symptoms was observed.
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Seven psychiatric inpatients receiving carbamazepine 600 mg/day were coadministered clarithromycin 400 mg/day for 5 days to treat atypical pneumonia.
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A mosaic karyotype with XY and XO was found on chromosomal analysis and gonadectomy was performed in view of the high risk of gonadoblastoma.
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Super potent topical corticosteroid use associated with adrenal suppression: clinical considerations.
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On hospital day 2 his platelet count dropped to 47,000/microl and bottomed out at 36,000/microl by day 3 with other blood cell counts remaining within normal limits.
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We consider asterixis to be an easily overlooked sign of neurotoxicity, which may occur even at low or moderate dosage levels, if certain drugs as lithium or clozapine are used in combination with CBZ.
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Chronic postoperative bacterial endophthalmitis has recently assumed a prominent role in differential diagnosis of inflammation following extracapsular cataract extraction with posterior chamber intraocular lens implantation.
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METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema.
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Additionally, ceftriaxone may cause problems in either adults or children with preexisting disease, who may not be well-nourished, or who may be dehydrated.
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Severe heparin associated thrombocytopenia is a rare complication of heparin therapy.
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C1-inhibitor deficiency, or hereditary angioedema, is a genetic disorder characterized by recurrent circumscribed, nonpruritic, nonpitting subepithelial edema.
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A severe form of exophthalmos resulting from lithium therapy has not been described in the literature.
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Ampicillin-associated seizures.
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Differentiation between recurrent tumor and radiation necrosis in a child with anaplastic ependymoma after chemotherapy and radiation therapy.
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Analysis of the pharmacokinetic data suggests that haemodialysis or haemofiltration would be more efficacious for removal of the drug, and these treatments should be performed if available.
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Two inactive patients received no corticosteroids before or after the diagnosis of pancreatitis.
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Even with the low dose of neuraxial drugs commonly administered in combined spinal-epidural labor analgesia, this case underscores the importance of vigilance, frequent monitoring, proper positioning, and rapid resuscitation with escalating doses of ephedrine, atropine, and epinephrine, all of which are essential in the presence of bradycardia or asystole in these patients.
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The case report of the corticosteroid complication in an eight-year-old girl with immune thrombocytopenic purpura is presented.
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A 17-year-old boy with acute lymphoblastic leukemia developed acute renal failure within 48 h of an intravenous high-dose methotrexate (5 g/m2) infusion.
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After a seizure-free period of 3 months the patient died from hepatic failure resembling Reye syndrome.
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Intranasal desmopressin provides symptomatic relief with few serious complications.
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The cost of care for the enterally supported child was less than one third of the TPN-supported child.
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We believe that this is the first report of secretory carcinoma of the endometrium associated with tamoxifen use.
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CONCLUSIONS: TNF-alpha inhibitors in general should be used cautiously in chronic hepatitis B viral infection.
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The patient was treated with radiofrequency cautery and is now asymptomatic.
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A patient developed transient, acute myopia while on isotretinoin (Accutane) therapy for acne.
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Combination of sodium thiosulphate, cinacalcet, and paricalcitol in the treatment of calciphylaxis with hyperparathyroidism.
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Pure red cell aplasia due to parvovirus B19 infection after liver transplantation: a case report and review of the literature.
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As a result, there have been several reports of children and adults on TPN who have developed WE as a result of thiamine deficiency.
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A mentally retarded 23-year-old woman with myoclonic astatic epilepsy developed an abnormal posture of extreme forward flexion, called camptocormia, during valproate monotherapy.
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The liver had zolpidem present at a concentration of 4.74 microg/g, and the gastric contents had a total of 172 mg zolpidem.
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One patient died with myeloid leukemia at 43.5 months after initial treatment.
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It also produces weak beta- and calcium-channel blockade.
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Disseminated superficial porokeratosis and immunosuppression.
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A 61-year-old man with early diffuse cutaneous scleroderma with myositis and progressive interstitial pneumonia developed generalized erythema with high fever 3 weeks after taking sulfamethoxazole/trimethoprim.
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Suramin has demonstrated modest activity against prostate cancer and is being investigated in clinical trials.
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A MEDLINE search identified all the reported cases of hypersensitivity reactions to cyclosporine.
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Symptomatic hypoglycemia secondary to a glipizide-trimethoprim/sulfamethoxazole drug interaction.
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However, he developed acute renal failure, hyperkalemia, and hyperuricemia 30 d after receiving the sorafenib treatment.
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This case and a review of the literature show the severe and unpredictable nature of ethambutol toxicity and its potential for irreversible vision loss despite careful ophthalmologic monitoring.
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All-trans retinoic acid-induced focal myositis, synovitis, and mononeuritis.
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We describe children and adolescents with chronic hematologic and oncologic diseases who exhibited drug-seeking behavior or anticholinergic symptoms with the use of diphenhydramine.
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Findings on discontinuation and rechallenge supported the assumption that the hair loss was a side effect of the paroxetine.
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Cutaneous alternariosis is an opportunistic infection.
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A 72-year-old woman was treated daily with two solutions including Tathion eye drops for senile cataract for two years and three months.
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Six of 13 outpatients with schizophrenia who participated in a ten-week open trial of risperidone had an initial good response to the medication followed by development of intolerable affect, including feelings of agitation and depression and periods of crying and insomnia.
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Therapeutic effect of intradermal injections with difucosyl lactosamine (dimeric Lex) on patients with rheumatoid arthritis.
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Ultrasound study revealed enlarged kidneys with increased echogenity and loss of corticomedullary differentiation.
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The development of erythroid leukemia plus carcinoma in these two men suggests mutagenic change secondary to cyclophosphamide therapy.
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Common adverse reactions of immunosuppressive treatment are infections, hematologic and liver function abnormalities, but neurologic complications may also be seen.
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The first patient developed mild nitritoid symptoms and pain in a band-like distribution, corresponding to T10-T12 dermatomes, shortly after gold sodium thiomalate (GSTM) injection.
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Incidence of seizures in pediatric cancer patients treated with imipenem/cilastatin.
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To keep the artery patent, i.c. streptokinase had to be continued until emergency bypass surgery was performed.
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METHODS: A retrospective review of patients originally diagnosed with ulcerative colitis, status post colectomy and IPAA, who developed findings compatible with Crohn's disease was undertaken.
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Although conventional MRI correlates have been described for this stroke-like syndrome, DWI data are largely unavailable.
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Rituximab is a chimeric anti-CD20 monoclonal antibody.
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Amphotericin B-induced seizures in a patient with AIDS.
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