name
stringlengths 8
27
| dna_seq
stringlengths 132
240
| log10_K50_t
float64 -2.41
6.1
| log10_K50_t_95CI_high
float64 -2.24
6.41
| log10_K50_t_95CI_low
float64 -2.83
5.13
| log10_K50_t_95CI
float64 0
1.28
| fitting_error_t
float64 0.01
3.53
| log10_K50unfolded_t
float64 -1.83
-0.26
| deltaG_t
float64 -15
15
| deltaG_t_95CI_high
float64 -5
25
| deltaG_t_95CI_low
float64 -25
8.38
| deltaG_t_95CI
float64 0.01
26.2
| log10_K50_c
float64 -3.22
1.98
| log10_K50_c_95CI_high
float64 -2.87
2
| log10_K50_c_95CI_low
float64 -3.69
1.94
| log10_K50_c_95CI
float64 0.01
1.74
| fitting_error_c
float64 0.01
2.01
| log10_K50unfolded_c
float64 -2.8
0.04
| deltaG_c
float64 -15
5.63
| deltaG_c_95CI_high
float64 -5
25
| deltaG_c_95CI_low
float64 -25
5.44
| deltaG_c_95CI
float64 0.01
25.8
| deltaG
float64 -1
5
| deltaG_95CI_high
float64 -0.96
5.32
| deltaG_95CI_low
float64 -1.42
4.95
| deltaG_95CI
float64 0.02
0.66
| aa_seq_full
stringlengths 44
80
| aa_seq
stringlengths 32
72
| mut_type
stringlengths 2
4
| WT_name
stringclasses 269
values | WT_cluster
stringclasses 107
values | log10_K50_trypsin_ML
stringlengths 1
23
| log10_K50_chymotrypsin_ML
stringlengths 1
23
| dG_ML
float64 -1
5
| ddG_ML
float64 -5.72
2.92
| Stabilizing_mut
stringclasses 3
values | pair_name
float64 | mutation
stringlengths 3
4
| base_aa_seq
stringclasses 266
values | classification
stringclasses 3
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2LGW.pdb_D64P | TCTGCGGGTTCTTACTACGAAATCCTGGATGTTCCGCGTTCTGCTTCTGCTGACGACATCAAAAAGGCGTACCGTCGCAAAGCGCTGCAATGGCACCCGGATAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAATTCAAAGAAGTTGCGGAAGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACCCACGCTCCGCTGGTGGT | -0.590608 | -0.551134 | -0.638571 | 0.087437 | 0.14132 | -1.481796 | 1.110896 | 1.171041 | 1.036722 | 0.134319 | -1.22882 | -1.078228 | -1.304859 | 0.226632 | 0.096491 | -2.371204 | 1.482627 | 1.696932 | 1.37234 | 0.324592 | 1.325549 | 1.406654 | 1.242903 | 0.16375 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYPRSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYPR | D64P | 2LGW.pdb | 192 | -0.5906084218360825 | -1.2288198736486915 | 1.325549 | -2.781339 | False | null | D64P | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_D64C | TCCGCTGGTGGTTCCGCGGGTTCTTACTACGAAATCCTGGACGTGCCGCGCTCTGCGTCTGCGGACGACATCAAGAAGGCGTACCGTCGTAAAGCGCTGCAATGGCACCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACTGCCGTTCTGCGGGTGGCTCTGCTGGCGGT | -0.199545 | -0.189411 | -0.213166 | 0.023755 | 0.047169 | -1.49468 | 1.700645 | 1.714919 | 1.68143 | 0.033489 | -0.988769 | -0.910089 | -1.059908 | 0.149819 | 0.046801 | -2.584309 | 2.116529 | 2.224221 | 2.018738 | 0.205483 | 1.956219 | 2.033465 | 1.894994 | 0.138472 | SAGGSAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYCRSAGGSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYCR | D64C | 2LGW.pdb | 192 | -0.1995446408070513 | -0.988768631401244 | 1.956219 | -2.150669 | False | null | D64C | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_R65Q | TCCGCGGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCGTCTGCTGATGACATCAAGAAAGCTTACCGTCGTAAAGCGCTGCAATGGCACCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAGAAGAAGTTCAAGGAAGTTGCGGAAGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGATCAGTCTGCGGGTGGT | 1.625352 | 1.739025 | 1.560622 | 0.178404 | 0.113907 | -1.316314 | 4.011013 | 4.190338 | 3.912219 | 0.278119 | 0.860784 | 0.88429 | 0.782065 | 0.102224 | 0.143918 | -2.400091 | 4.398277 | 4.432216 | 4.285609 | 0.146606 | 4.120463 | 4.30764 | 3.952095 | 0.355544 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDQSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDQ | R65Q | 2LGW.pdb | 192 | 1.6253522655081527 | 0.8607837000391754 | 4.120463 | 0.013574 | - | null | R65Q | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65E | TCCGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCGTCTGCTGACGACATCAAGAAAGCGTACCGTCGTAAAGCGCTGCAGTGGCACCCGGATAAAAACCCGGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCGTATGAAGTTCTGTCTGACAAACACAAACGTGAGATCTACGACGAATCTGCGGGTGGT | 1.129278 | 1.196441 | 0.974651 | 0.22179 | 0.124114 | -1.310892 | 3.281978 | 3.376307 | 3.066892 | 0.309415 | 0.510943 | 0.556299 | 0.480933 | 0.075367 | 0.116088 | -2.347162 | 3.835314 | 3.898111 | 3.793881 | 0.10423 | 3.561502 | 3.678972 | 3.448157 | 0.230815 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDESAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDE | R65E | 2LGW.pdb | 192 | 1.1292779571566482 | 0.5109428210455454 | 3.561502 | -0.545386 | False | null | R65E | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_R65N | TCTGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCGTCTGCGGACGACATCAAAAAGGCGTACCGTCGTAAAGCGCTGCAGTGGCATCCAGATAAAAACCCGGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACAACTCTGCGGGTGGT | 1.4304 | 1.541081 | 1.312147 | 0.228934 | 0.112751 | -1.314548 | 3.716475 | 3.880419 | 3.545488 | 0.334931 | 0.701006 | 0.750706 | 0.669197 | 0.081509 | 0.269389 | -2.396362 | 4.165963 | 4.236119 | 4.121285 | 0.114835 | 4.112525 | 4.274608 | 4.001838 | 0.27277 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDNSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDN | R65N | 2LGW.pdb | 192 | 1.4303997153876282 | 0.7010056650361466 | 4.112525 | 0.005636 | False | null | R65N | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65H | TCTGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCGTCTGCGGACGACATCAAGAAAGCGTACCGTCGTAAAGCGCTGCAGTGGCACCCGGATAAAAACCCGGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCGTATGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACCACTCTGCGGGTGGT | 1.062973 | 1.140559 | 0.975583 | 0.164975 | 0.174901 | -1.314393 | 3.194133 | 3.302469 | 3.072882 | 0.229587 | 0.562177 | 0.624725 | 0.527899 | 0.096826 | 0.183692 | -2.431915 | 4.01958 | 4.106604 | 3.972089 | 0.134516 | 3.703214 | 3.89536 | 3.57989 | 0.315471 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDHSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDH | R65H | 2LGW.pdb | 192 | 1.062973103623337 | 0.5621766075022998 | 3.703214 | -0.403675 | False | null | R65H | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65D | TCTGCGGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCGGACGACATCAAGAAAGCGTACCGTCGTAAAGCGCTGCAATGGCACCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCTTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACGACTCTGCTGGTGGT | 0.626517 | 0.707453 | 0.555986 | 0.151468 | 0.174432 | -1.310365 | 2.587772 | 2.69863 | 2.491202 | 0.207427 | -0.15908 | -0.119746 | -0.245953 | 0.126206 | 0.164045 | -2.346518 | 2.921578 | 2.97482 | 2.803985 | 0.170835 | 2.914548 | 3.189587 | 2.679775 | 0.509812 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDDSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDD | R65D | 2LGW.pdb | 192 | 0.6265170044157206 | -0.1590798762084111 | 2.914548 | -1.19234 | False | null | R65D | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_R65K | TCTGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCGTCTGCGGACGACATCAAGAAAGCGTATCGTCGTAAAGCGCTGCAGTGGCACCCAGATAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAATTCAAAGAAGTTGCGGAAGCGTACGAAGTTCTGTCCGACAAACACAAACGTGAAATCTACGACAAATCTGCGGGTGGT | 1.577665 | 1.643257 | 1.480468 | 0.162789 | 0.081517 | -1.331782 | 3.958718 | 4.059404 | 3.813146 | 0.246258 | 0.789626 | 0.820065 | 0.765624 | 0.054441 | 0.082411 | -2.418726 | 4.321272 | 4.364719 | 4.287154 | 0.077566 | 4.166234 | 4.247353 | 4.078775 | 0.168577 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDKSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDK | R65K | 2LGW.pdb | 192 | 1.5776654620820754 | 0.7896257848121092 | 4.166234 | 0.059345 | - | null | R65K | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65T | TCTGCGGGCTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCGGACGACATCAAGAAAGCTTACCGTCGTAAAGCGCTGCAGTGGCACCCGGATAAAAACCCGGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCGTATGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACACCTCCGCGGGTGGT | 1.24165 | 1.324644 | 1.196105 | 0.128539 | 0.123117 | -1.315836 | 3.446824 | 3.565117 | 3.382458 | 0.182659 | 0.361553 | 0.371182 | 0.345947 | 0.025235 | 0.087396 | -2.392111 | 3.689983 | 3.703171 | 3.668622 | 0.034549 | 3.652479 | 3.70654 | 3.552667 | 0.153874 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDTSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDT | R65T | 2LGW.pdb | 192 | 1.241650052544264 | 0.3615527907375798 | 3.652479 | -0.45441 | False | null | R65T | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65S | TCCGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCGTCTGCTGACGACATCAAAAAGGCGTACCGTCGTAAAGCGCTGCAGTGGCACCCGGATAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAGTTCAAAGAGGTTGCGGAAGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACTCTTCTGCGGGTGGT | 1.549854 | 1.663003 | 1.434154 | 0.228849 | 0.13478 | -1.315376 | 3.894723 | 4.068244 | 3.723075 | 0.345169 | 0.625785 | 0.67433 | 0.559406 | 0.114923 | 0.095524 | -2.404999 | 4.072104 | 4.140027 | 3.979752 | 0.160275 | 3.971823 | 4.125037 | 3.839313 | 0.285724 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDSSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDS | R65S | 2LGW.pdb | 192 | 1.5498535606884332 | 0.6257847653695525 | 3.971823 | -0.135066 | - | null | R65S | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65A | TCTGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCTGATGACATCAAAAAGGCGTACCGTCGTAAAGCGCTCCAGTGGCACCCGGATAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAGTTCAAAGAGGTTGCGGAAGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGATGCGTCTGCGGGTGGT | 1.608315 | 1.78089 | 1.327917 | 0.452973 | 0.295004 | -1.319318 | 3.988824 | 4.262755 | 3.574473 | 0.688282 | 0.373313 | 0.514203 | 0.30355 | 0.210654 | 0.212917 | -2.423859 | 3.74856 | 3.942378 | 3.653151 | 0.289227 | 3.96388 | 4.142388 | 3.673149 | 0.46924 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDASAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDA | R65A | 2LGW.pdb | 192 | 1.6083153921206963 | 0.3733129271454595 | 3.96388 | -0.143009 | - | null | R65A | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65G | TCCGCGGGTTCTTACTACGAGATCCTGGACGTTCCGCGCTCCGCGTCTGCTGATGACATCAAGAAAGCGTACCGCCGTAAAGCGCTGCAGTGGCACCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAATTCAAAGAAGTTGCGGAAGCGTATGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACGGTTCTGCGGGTGGT | 1.349143 | 1.418701 | 1.259865 | 0.158836 | 0.073593 | -1.316093 | 3.600667 | 3.701457 | 3.473012 | 0.228445 | 0.428239 | 0.438276 | 0.419605 | 0.01867 | 0.093824 | -2.3927 | 3.782246 | 3.796043 | 3.770383 | 0.02566 | 3.70087 | 3.773062 | 3.643543 | 0.129519 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDGSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDG | R65G | 2LGW.pdb | 192 | 1.3491434960658102 | 0.4282392065891905 | 3.70087 | -0.406019 | False | null | R65G | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65M | TCCGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCGGACGACATCAAGAAAGCTTACCGTCGTAAAGCGCTCCAGTGGCATCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAGAAGAAATTCAAGGAAGTTGCGGAGGCGTACGAGGTTCTGTCTGACAAACACAAACGTGAAATTTACGATATGTCCGCGGGTGGT | 1.426528 | 1.527389 | 1.315098 | 0.212291 | 0.11035 | -1.326389 | 3.726658 | 3.875725 | 3.565562 | 0.310163 | 0.725564 | 0.770993 | 0.694248 | 0.076745 | 0.170478 | -2.47226 | 4.302004 | 4.366313 | 4.257893 | 0.10842 | 4.076635 | 4.244261 | 3.973888 | 0.270374 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDMSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDM | R65M | 2LGW.pdb | 192 | 1.4265282980115677 | 0.7255636039031532 | 4.076635 | -0.030253 | False | null | R65M | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65L | TCCGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGCTCTGCGTCTGCGGACGACATCAAGAAAGCTTACCGTCGTAAAGCGCTCCAGTGGCACCCGGATAAAAACCCGGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCGTACGAAGTTCTGTCCGACAAACACAAACGTGAAATCTACGACCTGTCCGCGGGTGGT | 1.515422 | 1.669132 | 1.427392 | 0.24174 | 0.234485 | -1.325489 | 3.856641 | 4.091363 | 3.726717 | 0.364646 | 0.553345 | 0.573959 | 0.510906 | 0.063053 | 0.177442 | -2.49378 | 4.090031 | 4.118632 | 4.031302 | 0.08733 | 3.89254 | 4.086462 | 3.684727 | 0.401735 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDLSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDL | R65L | 2LGW.pdb | 192 | 1.5154223171701868 | 0.5533449016159164 | 3.89254 | -0.214349 | - | null | R65L | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65V | TCCGCGGGTTCTTACTACGAAATCCTGGACGTTCCGCGCTCTGCGTCTGCTGACGACATCAAGAAAGCGTACCGTCGTAAAGCGCTCCAGTGGCACCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAATTCAAAGAAGTTGCGGAAGCTTACGAAGTTCTGTCTGACAAGCACAAACGTGAAATCTACGACGTTTCTGCGGGTGGT | 0.952506 | 1.017356 | 0.859665 | 0.15769 | 0.204112 | -1.318968 | 3.047118 | 3.13689 | 2.919138 | 0.217751 | 0.378158 | 0.428483 | 0.332668 | 0.095815 | 0.172344 | -2.415518 | 3.744041 | 3.813099 | 3.681777 | 0.131322 | 3.53717 | 3.744415 | 3.384674 | 0.359741 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDVSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDV | R65V | 2LGW.pdb | 192 | 0.9525057564082448 | 0.3781580186706236 | 3.53717 | -0.569718 | False | null | R65V | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_R65I | TCCGCTGGCTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCTGACGACATCAAGAAGGCGTACCGTCGTAAAGCGCTGCAGTGGCACCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCTTACGAAGTTCTGTCTGACAAGCACAAACGTGAGATCTACGACATTTCTGCGGGTGGT | 1.215222 | 1.261643 | 1.147979 | 0.113665 | 0.143087 | -1.321604 | 3.417157 | 3.482917 | 3.322533 | 0.160384 | 0.598011 | 0.68823 | 0.535598 | 0.152633 | 0.114315 | -2.454962 | 4.100182 | 4.226319 | 4.013555 | 0.212764 | 3.730235 | 3.945732 | 3.583572 | 0.362161 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDISAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDI | R65I | 2LGW.pdb | 192 | 1.2152222332173497 | 0.5980110153699976 | 3.730235 | -0.376654 | False | null | R65I | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |
2LGW.pdb_R65W | TCTGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCGGACGACATCAAGAAAGCGTACCGTCGTAAAGCGCTGCAGTGGCACCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAATTCAAAGAAGTTGCTGAGGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACTGGTCTGCGGGTGGT | 1.053661 | 1.111172 | 0.998028 | 0.113144 | 0.07195 | -1.336055 | 3.210229 | 3.290385 | 3.133024 | 0.15736 | 0.136958 | 0.15082 | 0.130225 | 0.020595 | 0.060454 | -2.48938 | 3.514105 | 3.532923 | 3.504967 | 0.027955 | 3.393986 | 3.455631 | 3.34587 | 0.10976 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDWSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDW | R65W | 2LGW.pdb | 192 | 1.0536605543027673 | 0.1369581741242436 | 3.393986 | -0.712903 | False | null | R65W | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_R65Y | TCTGCTGGCTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCGGACGACATCAAGAAAGCGTACCGTCGTAAAGCGCTGCAGTGGCACCCGGATAAGAACCCGGACAACAAAGAATTCGCGGAAAAGAAGTTTAAAGAGGTTGCGGAGGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACTACTCTGCGGGTGGT | 1.300015 | 1.385254 | 1.211284 | 0.17397 | 0.159616 | -1.328533 | 3.54686 | 3.669474 | 3.420876 | 0.248598 | 0.13943 | 0.16429 | 0.124843 | 0.039447 | 0.172504 | -2.458939 | 3.476707 | 3.510467 | 3.456908 | 0.053559 | 3.535794 | 3.75699 | 3.366925 | 0.390065 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDYSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDY | R65Y | 2LGW.pdb | 192 | 1.3000150807086994 | 0.1394303255384493 | 3.535794 | -0.571095 | False | null | R65Y | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_R65F | TCCGCTGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCGGACGACATCAAGAAAGCGTACCGTCGTAAAGCGCTGCAGTGGCACCCAGACAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAATTCAAAGAAGTTGCTGAGGCGTACGAGGTTCTGTCTGACAAACACAAACGTGAAATCTACGACTTCTCCGCGGGTGGT | 1.090282 | 1.126341 | 1.00187 | 0.124471 | 0.062374 | -1.331614 | 3.255271 | 3.305641 | 3.132387 | 0.173254 | 0.156984 | 0.174973 | 0.147802 | 0.027171 | 0.066537 | -2.477896 | 3.52592 | 3.550356 | 3.513452 | 0.036904 | 3.421941 | 3.502232 | 3.341127 | 0.161104 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDFSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDF | R65F | 2LGW.pdb | 192 | 1.090282207661669 | 0.1569843434223361 | 3.421941 | -0.684947 | False | null | R65F | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_R65P | TCTGCGGGTTCTTACTACGAAATCCTGGACGTTCCGCGTTCTGCTTCTGCGGACGACATCAAGAAAGCGTACCGTCGTAAAGCGCTGCAGTGGCACCCGGACAAAAACCCAGACAACAAAGAATTCGCGGAGAAAAAGTTCAAAGAAGTTGCGGAAGCGTATGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACCCGTCTGCTGGTGGT | 0.381193 | 0.420709 | 0.341256 | 0.079453 | 0.065303 | -1.312298 | 2.254217 | 2.308456 | 2.199335 | 0.109121 | -0.58864 | -0.56157 | -0.612153 | 0.050583 | 0.103159 | -2.349171 | 2.34253 | 2.379397 | 2.310479 | 0.068917 | 2.288848 | 2.385839 | 2.240243 | 0.145596 | SAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDPSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDP | R65P | 2LGW.pdb | 192 | 0.3811933422980442 | -0.5886399132432746 | 2.288848 | -1.818041 | False | null | R65P | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | destabilising |
2LGW.pdb_R65C | TCCGCGGGTGGCTCTGCGGGTTCTTACTACGAAATCCTGGATGTTCCGCGCTCCGCTTCTGCTGACGACATCAAGAAGGCGTACCGTCGTAAAGCGCTGCAATGGCACCCGGATAAAAACCCGGACAACAAAGAATTCGCGGAAAAGAAATTCAAAGAAGTTGCGGAAGCGTACGAAGTTCTGTCTGACAAACACAAACGTGAAATCTACGACTGCTCTGCTGGCGGTTCCGCTGGTGGT | 1.238985 | 1.26501 | 1.217294 | 0.047716 | 0.062388 | -1.3342 | 3.467639 | 3.504566 | 3.436954 | 0.067612 | 0.463817 | 0.479403 | 0.421829 | 0.057574 | 0.081451 | -2.427298 | 3.877461 | 3.898938 | 3.819711 | 0.079227 | 3.805352 | 3.867399 | 3.767399 | 0.099999 | SAGGSAGSYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDCSAGGSAGG | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDC | R65C | 2LGW.pdb | 192 | 1.2389850041840924 | 0.4638168003608705 | 3.805352 | -0.301537 | False | null | R65C | SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR | neutral |