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5a6b9bf84eec6b001a80a4a3
Myocardial_infarction
Acute myocardial infarction refers to two subtypes of acute coronary syndrome, namely non-ST-elevated and ST-elevated MIs, which are most frequently (but not always) a manifestation of coronary artery disease. The most common triggering event is the disruption of an atherosclerotic plaque in an epicardial coronary artery, which leads to a clotting cascade, sometimes resulting in total occlusion of the artery. Atherosclerosis is the gradual buildup of cholesterol and fibrous tissue in plaques in the wall of arteries (in this case, the coronary arteries), typically over decades. Bloodstream column irregularities visible on angiography reflect artery lumen narrowing as a result of decades of advancing atherosclerosis. Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that occludes the artery; this can occur in minutes. When a severe enough plaque rupture occurs in the coronary arteries, it leads to MI (necrosis of downstream myocardium). It is estimated that one billion cardiac cells are lost in a typical MI.
What are always a manifestation of artery disease?
{ "text": [], "answer_start": [] }
5a6b9bf84eec6b001a80a4a4
Myocardial_infarction
Acute myocardial infarction refers to two subtypes of acute coronary syndrome, namely non-ST-elevated and ST-elevated MIs, which are most frequently (but not always) a manifestation of coronary artery disease. The most common triggering event is the disruption of an atherosclerotic plaque in an epicardial coronary artery, which leads to a clotting cascade, sometimes resulting in total occlusion of the artery. Atherosclerosis is the gradual buildup of cholesterol and fibrous tissue in plaques in the wall of arteries (in this case, the coronary arteries), typically over decades. Bloodstream column irregularities visible on angiography reflect artery lumen narrowing as a result of decades of advancing atherosclerosis. Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that occludes the artery; this can occur in minutes. When a severe enough plaque rupture occurs in the coronary arteries, it leads to MI (necrosis of downstream myocardium). It is estimated that one billion cardiac cells are lost in a typical MI.
How long does an MI take?
{ "text": [], "answer_start": [] }
5a6b9bf84eec6b001a80a4a5
Myocardial_infarction
Acute myocardial infarction refers to two subtypes of acute coronary syndrome, namely non-ST-elevated and ST-elevated MIs, which are most frequently (but not always) a manifestation of coronary artery disease. The most common triggering event is the disruption of an atherosclerotic plaque in an epicardial coronary artery, which leads to a clotting cascade, sometimes resulting in total occlusion of the artery. Atherosclerosis is the gradual buildup of cholesterol and fibrous tissue in plaques in the wall of arteries (in this case, the coronary arteries), typically over decades. Bloodstream column irregularities visible on angiography reflect artery lumen narrowing as a result of decades of advancing atherosclerosis. Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that occludes the artery; this can occur in minutes. When a severe enough plaque rupture occurs in the coronary arteries, it leads to MI (necrosis of downstream myocardium). It is estimated that one billion cardiac cells are lost in a typical MI.
How many plaques become unstable in a typical MI?
{ "text": [], "answer_start": [] }
5a6b9bf84eec6b001a80a4a6
Myocardial_infarction
Acute myocardial infarction refers to two subtypes of acute coronary syndrome, namely non-ST-elevated and ST-elevated MIs, which are most frequently (but not always) a manifestation of coronary artery disease. The most common triggering event is the disruption of an atherosclerotic plaque in an epicardial coronary artery, which leads to a clotting cascade, sometimes resulting in total occlusion of the artery. Atherosclerosis is the gradual buildup of cholesterol and fibrous tissue in plaques in the wall of arteries (in this case, the coronary arteries), typically over decades. Bloodstream column irregularities visible on angiography reflect artery lumen narrowing as a result of decades of advancing atherosclerosis. Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that occludes the artery; this can occur in minutes. When a severe enough plaque rupture occurs in the coronary arteries, it leads to MI (necrosis of downstream myocardium). It is estimated that one billion cardiac cells are lost in a typical MI.
How long does an angiography take?
{ "text": [], "answer_start": [] }
5a6bb05e4eec6b001a80a4b6
Myocardial_infarction
If impaired blood flow to the heart lasts long enough, it triggers a process called the ischemic cascade; the heart cells in the territory of the occluded coronary artery die (chiefly through necrosis) and do not grow back. A collagen scar forms in their place. Recent studies indicate that another form of cell death, apoptosis, also plays a role in the process of tissue damage following an MI. As a result, the person's heart will be permanently damaged. This myocardial scarring also puts the person at risk for potentially life-threatening abnormal heart rhythms (arrhythmias), and may result in the formation of a ventricular aneurysm that can rupture with catastrophic consequences.
What does necrosis trigger?
{ "text": [], "answer_start": [] }
5a6bb05e4eec6b001a80a4b7
Myocardial_infarction
If impaired blood flow to the heart lasts long enough, it triggers a process called the ischemic cascade; the heart cells in the territory of the occluded coronary artery die (chiefly through necrosis) and do not grow back. A collagen scar forms in their place. Recent studies indicate that another form of cell death, apoptosis, also plays a role in the process of tissue damage following an MI. As a result, the person's heart will be permanently damaged. This myocardial scarring also puts the person at risk for potentially life-threatening abnormal heart rhythms (arrhythmias), and may result in the formation of a ventricular aneurysm that can rupture with catastrophic consequences.
What is a collagen scar called?
{ "text": [], "answer_start": [] }
5a6bb05e4eec6b001a80a4b8
Myocardial_infarction
If impaired blood flow to the heart lasts long enough, it triggers a process called the ischemic cascade; the heart cells in the territory of the occluded coronary artery die (chiefly through necrosis) and do not grow back. A collagen scar forms in their place. Recent studies indicate that another form of cell death, apoptosis, also plays a role in the process of tissue damage following an MI. As a result, the person's heart will be permanently damaged. This myocardial scarring also puts the person at risk for potentially life-threatening abnormal heart rhythms (arrhythmias), and may result in the formation of a ventricular aneurysm that can rupture with catastrophic consequences.
What is another name for a ventricular aneurysm?
{ "text": [], "answer_start": [] }
5a6bb05e4eec6b001a80a4b9
Myocardial_infarction
If impaired blood flow to the heart lasts long enough, it triggers a process called the ischemic cascade; the heart cells in the territory of the occluded coronary artery die (chiefly through necrosis) and do not grow back. A collagen scar forms in their place. Recent studies indicate that another form of cell death, apoptosis, also plays a role in the process of tissue damage following an MI. As a result, the person's heart will be permanently damaged. This myocardial scarring also puts the person at risk for potentially life-threatening abnormal heart rhythms (arrhythmias), and may result in the formation of a ventricular aneurysm that can rupture with catastrophic consequences.
apoptosis is the death of what artery?
{ "text": [], "answer_start": [] }
5a6bb05e4eec6b001a80a4ba
Myocardial_infarction
If impaired blood flow to the heart lasts long enough, it triggers a process called the ischemic cascade; the heart cells in the territory of the occluded coronary artery die (chiefly through necrosis) and do not grow back. A collagen scar forms in their place. Recent studies indicate that another form of cell death, apoptosis, also plays a role in the process of tissue damage following an MI. As a result, the person's heart will be permanently damaged. This myocardial scarring also puts the person at risk for potentially life-threatening abnormal heart rhythms (arrhythmias), and may result in the formation of a ventricular aneurysm that can rupture with catastrophic consequences.
What is impaired blood flow called?
{ "text": [], "answer_start": [] }
5a6bb13e4eec6b001a80a4c0
Myocardial_infarction
Injured heart tissue conducts electrical impulses more slowly than normal heart tissue. The difference in conduction velocity between injured and uninjured tissue can trigger re-entry or a feedback loop that is believed to be the cause of many lethal arrhythmias. The most serious of these arrhythmias is ventricular fibrillation (V-Fib/VF), an extremely fast and chaotic heart rhythm that is the leading cause of sudden cardiac death. Another life-threatening arrhythmia is ventricular tachycardia (V-tach/VT), which can cause sudden cardiac death. However, VT usually results in rapid heart rates that prevent the heart from pumping blood effectively. Cardiac output and blood pressure may fall to dangerous levels, which can lead to further coronary ischemia and extension of the infarct.
Normal heart tissue is slower than what?
{ "text": [], "answer_start": [] }
5a6bb13e4eec6b001a80a4c1
Myocardial_infarction
Injured heart tissue conducts electrical impulses more slowly than normal heart tissue. The difference in conduction velocity between injured and uninjured tissue can trigger re-entry or a feedback loop that is believed to be the cause of many lethal arrhythmias. The most serious of these arrhythmias is ventricular fibrillation (V-Fib/VF), an extremely fast and chaotic heart rhythm that is the leading cause of sudden cardiac death. Another life-threatening arrhythmia is ventricular tachycardia (V-tach/VT), which can cause sudden cardiac death. However, VT usually results in rapid heart rates that prevent the heart from pumping blood effectively. Cardiac output and blood pressure may fall to dangerous levels, which can lead to further coronary ischemia and extension of the infarct.
What is the name of the arrhythmia that is slower than normal?
{ "text": [], "answer_start": [] }
5a6bb13e4eec6b001a80a4c2
Myocardial_infarction
Injured heart tissue conducts electrical impulses more slowly than normal heart tissue. The difference in conduction velocity between injured and uninjured tissue can trigger re-entry or a feedback loop that is believed to be the cause of many lethal arrhythmias. The most serious of these arrhythmias is ventricular fibrillation (V-Fib/VF), an extremely fast and chaotic heart rhythm that is the leading cause of sudden cardiac death. Another life-threatening arrhythmia is ventricular tachycardia (V-tach/VT), which can cause sudden cardiac death. However, VT usually results in rapid heart rates that prevent the heart from pumping blood effectively. Cardiac output and blood pressure may fall to dangerous levels, which can lead to further coronary ischemia and extension of the infarct.
V-tach is the leading cause of what?
{ "text": [], "answer_start": [] }
5a6bb13e4eec6b001a80a4c3
Myocardial_infarction
Injured heart tissue conducts electrical impulses more slowly than normal heart tissue. The difference in conduction velocity between injured and uninjured tissue can trigger re-entry or a feedback loop that is believed to be the cause of many lethal arrhythmias. The most serious of these arrhythmias is ventricular fibrillation (V-Fib/VF), an extremely fast and chaotic heart rhythm that is the leading cause of sudden cardiac death. Another life-threatening arrhythmia is ventricular tachycardia (V-tach/VT), which can cause sudden cardiac death. However, VT usually results in rapid heart rates that prevent the heart from pumping blood effectively. Cardiac output and blood pressure may fall to dangerous levels, which can lead to further coronary ischemia and extension of the infarct.
Electrical impulses trigger what?
{ "text": [], "answer_start": [] }
5a6bb13e4eec6b001a80a4c4
Myocardial_infarction
Injured heart tissue conducts electrical impulses more slowly than normal heart tissue. The difference in conduction velocity between injured and uninjured tissue can trigger re-entry or a feedback loop that is believed to be the cause of many lethal arrhythmias. The most serious of these arrhythmias is ventricular fibrillation (V-Fib/VF), an extremely fast and chaotic heart rhythm that is the leading cause of sudden cardiac death. Another life-threatening arrhythmia is ventricular tachycardia (V-tach/VT), which can cause sudden cardiac death. However, VT usually results in rapid heart rates that prevent the heart from pumping blood effectively. Cardiac output and blood pressure may fall to dangerous levels, which can lead to further coronary ischemia and extension of the infarct.
A rising blood pressure can cause additional what?
{ "text": [], "answer_start": [] }
5a6bb1d34eec6b001a80a4d4
Myocardial_infarction
Myocardial infarction in the setting of plaque results from underlying atherosclerosis. Inflammation is known to be an important step in the process of atherosclerotic plaque formation. C-reactive protein (CRP) is a sensitive but nonspecific marker for inflammation. Elevated CRP blood levels, especially measured with high-sensitivity assays, can predict the risk of MI, as well as stroke and development of diabetes. Moreover, some drugs for MI might also reduce CRP levels. The use of high-sensitivity CRP assays as a means of screening the general population is advised against, but it may be used optionally at the physician's discretion in those who already present with other risk factors or known coronary artery disease. Whether CRP plays a direct role in atherosclerosis remains uncertain.
The setting of plaque is called what?
{ "text": [], "answer_start": [] }
5a6bb1d34eec6b001a80a4d5
Myocardial_infarction
Myocardial infarction in the setting of plaque results from underlying atherosclerosis. Inflammation is known to be an important step in the process of atherosclerotic plaque formation. C-reactive protein (CRP) is a sensitive but nonspecific marker for inflammation. Elevated CRP blood levels, especially measured with high-sensitivity assays, can predict the risk of MI, as well as stroke and development of diabetes. Moreover, some drugs for MI might also reduce CRP levels. The use of high-sensitivity CRP assays as a means of screening the general population is advised against, but it may be used optionally at the physician's discretion in those who already present with other risk factors or known coronary artery disease. Whether CRP plays a direct role in atherosclerosis remains uncertain.
CRP is known to play a direct role in what?
{ "text": [], "answer_start": [] }
5a6bb1d34eec6b001a80a4d6
Myocardial_infarction
Myocardial infarction in the setting of plaque results from underlying atherosclerosis. Inflammation is known to be an important step in the process of atherosclerotic plaque formation. C-reactive protein (CRP) is a sensitive but nonspecific marker for inflammation. Elevated CRP blood levels, especially measured with high-sensitivity assays, can predict the risk of MI, as well as stroke and development of diabetes. Moreover, some drugs for MI might also reduce CRP levels. The use of high-sensitivity CRP assays as a means of screening the general population is advised against, but it may be used optionally at the physician's discretion in those who already present with other risk factors or known coronary artery disease. Whether CRP plays a direct role in atherosclerosis remains uncertain.
What specific marker indicates inflammation?
{ "text": [], "answer_start": [] }
5a6bb1d34eec6b001a80a4d7
Myocardial_infarction
Myocardial infarction in the setting of plaque results from underlying atherosclerosis. Inflammation is known to be an important step in the process of atherosclerotic plaque formation. C-reactive protein (CRP) is a sensitive but nonspecific marker for inflammation. Elevated CRP blood levels, especially measured with high-sensitivity assays, can predict the risk of MI, as well as stroke and development of diabetes. Moreover, some drugs for MI might also reduce CRP levels. The use of high-sensitivity CRP assays as a means of screening the general population is advised against, but it may be used optionally at the physician's discretion in those who already present with other risk factors or known coronary artery disease. Whether CRP plays a direct role in atherosclerosis remains uncertain.
Drugs for MI tend to raise what?
{ "text": [], "answer_start": [] }
5a6bb1d34eec6b001a80a4d8
Myocardial_infarction
Myocardial infarction in the setting of plaque results from underlying atherosclerosis. Inflammation is known to be an important step in the process of atherosclerotic plaque formation. C-reactive protein (CRP) is a sensitive but nonspecific marker for inflammation. Elevated CRP blood levels, especially measured with high-sensitivity assays, can predict the risk of MI, as well as stroke and development of diabetes. Moreover, some drugs for MI might also reduce CRP levels. The use of high-sensitivity CRP assays as a means of screening the general population is advised against, but it may be used optionally at the physician's discretion in those who already present with other risk factors or known coronary artery disease. Whether CRP plays a direct role in atherosclerosis remains uncertain.
What type of screening is generally recommended?
{ "text": [], "answer_start": [] }
5a6bb2904eec6b001a80a4de
Myocardial_infarction
For a person to qualify as having a STEMI, in addition to reported angina, the ECG must show new ST elevation in two or more adjacent ECG leads. This must be greater than 2 mm (0.2 mV) for males and greater than 1.5 mm (0.15 mV) in females if in leads V2 and V3 or greater than 1 mm (0.1 mV) if it is in other ECG leads. A left bundle branch block that is believed to be new used to be considered the same as ST elevation; however, this is no longer the case. In early STEMIs there may just be peaked T waves with ST elevation developing later.
How many anginas must a person report to have a STEMI?
{ "text": [], "answer_start": [] }
5a6bb2904eec6b001a80a4df
Myocardial_infarction
For a person to qualify as having a STEMI, in addition to reported angina, the ECG must show new ST elevation in two or more adjacent ECG leads. This must be greater than 2 mm (0.2 mV) for males and greater than 1.5 mm (0.15 mV) in females if in leads V2 and V3 or greater than 1 mm (0.1 mV) if it is in other ECG leads. A left bundle branch block that is believed to be new used to be considered the same as ST elevation; however, this is no longer the case. In early STEMIs there may just be peaked T waves with ST elevation developing later.
ST elevation can develop into what?
{ "text": [], "answer_start": [] }
5a6bb2904eec6b001a80a4e0
Myocardial_infarction
For a person to qualify as having a STEMI, in addition to reported angina, the ECG must show new ST elevation in two or more adjacent ECG leads. This must be greater than 2 mm (0.2 mV) for males and greater than 1.5 mm (0.15 mV) in females if in leads V2 and V3 or greater than 1 mm (0.1 mV) if it is in other ECG leads. A left bundle branch block that is believed to be new used to be considered the same as ST elevation; however, this is no longer the case. In early STEMIs there may just be peaked T waves with ST elevation developing later.
The ECG must show less than how many mV for a male to be considered a STEMI?
{ "text": [], "answer_start": [] }
5a6bb2904eec6b001a80a4e1
Myocardial_infarction
For a person to qualify as having a STEMI, in addition to reported angina, the ECG must show new ST elevation in two or more adjacent ECG leads. This must be greater than 2 mm (0.2 mV) for males and greater than 1.5 mm (0.15 mV) in females if in leads V2 and V3 or greater than 1 mm (0.1 mV) if it is in other ECG leads. A left bundle branch block that is believed to be new used to be considered the same as ST elevation; however, this is no longer the case. In early STEMIs there may just be peaked T waves with ST elevation developing later.
What has recently been added as a qualification for a STEMI?
{ "text": [], "answer_start": [] }
5a6bb2904eec6b001a80a4e2
Myocardial_infarction
For a person to qualify as having a STEMI, in addition to reported angina, the ECG must show new ST elevation in two or more adjacent ECG leads. This must be greater than 2 mm (0.2 mV) for males and greater than 1.5 mm (0.15 mV) in females if in leads V2 and V3 or greater than 1 mm (0.1 mV) if it is in other ECG leads. A left bundle branch block that is believed to be new used to be considered the same as ST elevation; however, this is no longer the case. In early STEMIs there may just be peaked T waves with ST elevation developing later.
Which two named leads only have to be above 1 mm to be counted?
{ "text": [], "answer_start": [] }
5a6bb3444eec6b001a80a4e8
Myocardial_infarction
In stable patients whose symptoms have resolved by the time of evaluation, technetium (99mTc) sestamibi (i.e. a "MIBI scan") or thallium-201 chloride can be used in nuclear medicine to visualize areas of reduced blood flow in conjunction with physiological or pharmacological stress. Thallium may also be used to determine viability of tissue, distinguishing whether nonfunctional myocardium is actually dead or merely in a state of hibernation or of being stunned. Medical societies and professional guidelines recommend that the physician confirm a person is at high risk for myocardial infarction before conducting imaging tests to make a diagnosis. Patients who have a normal ECG and who are able to exercise, for example, do not merit routine imaging. Imaging tests such as stress radionuclide myocardial perfusion imaging or stress echocardiography can confirm a diagnosis when a patient's history, physical exam, ECG, and cardiac biomarkers suggest the likelihood of a problem.
What is used to examine blood flood in unstable patients?
{ "text": [], "answer_start": [] }
5a6bb3444eec6b001a80a4e9
Myocardial_infarction
In stable patients whose symptoms have resolved by the time of evaluation, technetium (99mTc) sestamibi (i.e. a "MIBI scan") or thallium-201 chloride can be used in nuclear medicine to visualize areas of reduced blood flow in conjunction with physiological or pharmacological stress. Thallium may also be used to determine viability of tissue, distinguishing whether nonfunctional myocardium is actually dead or merely in a state of hibernation or of being stunned. Medical societies and professional guidelines recommend that the physician confirm a person is at high risk for myocardial infarction before conducting imaging tests to make a diagnosis. Patients who have a normal ECG and who are able to exercise, for example, do not merit routine imaging. Imaging tests such as stress radionuclide myocardial perfusion imaging or stress echocardiography can confirm a diagnosis when a patient's history, physical exam, ECG, and cardiac biomarkers suggest the likelihood of a problem.
What is another name for thallium-201?
{ "text": [], "answer_start": [] }
5a6bb3444eec6b001a80a4ea
Myocardial_infarction
In stable patients whose symptoms have resolved by the time of evaluation, technetium (99mTc) sestamibi (i.e. a "MIBI scan") or thallium-201 chloride can be used in nuclear medicine to visualize areas of reduced blood flow in conjunction with physiological or pharmacological stress. Thallium may also be used to determine viability of tissue, distinguishing whether nonfunctional myocardium is actually dead or merely in a state of hibernation or of being stunned. Medical societies and professional guidelines recommend that the physician confirm a person is at high risk for myocardial infarction before conducting imaging tests to make a diagnosis. Patients who have a normal ECG and who are able to exercise, for example, do not merit routine imaging. Imaging tests such as stress radionuclide myocardial perfusion imaging or stress echocardiography can confirm a diagnosis when a patient's history, physical exam, ECG, and cardiac biomarkers suggest the likelihood of a problem.
What purpose does technetium serve in terms of identifying tissue?
{ "text": [], "answer_start": [] }
5a6bb3444eec6b001a80a4eb
Myocardial_infarction
In stable patients whose symptoms have resolved by the time of evaluation, technetium (99mTc) sestamibi (i.e. a "MIBI scan") or thallium-201 chloride can be used in nuclear medicine to visualize areas of reduced blood flow in conjunction with physiological or pharmacological stress. Thallium may also be used to determine viability of tissue, distinguishing whether nonfunctional myocardium is actually dead or merely in a state of hibernation or of being stunned. Medical societies and professional guidelines recommend that the physician confirm a person is at high risk for myocardial infarction before conducting imaging tests to make a diagnosis. Patients who have a normal ECG and who are able to exercise, for example, do not merit routine imaging. Imaging tests such as stress radionuclide myocardial perfusion imaging or stress echocardiography can confirm a diagnosis when a patient's history, physical exam, ECG, and cardiac biomarkers suggest the likelihood of a problem.
What must be determined after taking an imaging test?
{ "text": [], "answer_start": [] }
5a6bb3444eec6b001a80a4ec
Myocardial_infarction
In stable patients whose symptoms have resolved by the time of evaluation, technetium (99mTc) sestamibi (i.e. a "MIBI scan") or thallium-201 chloride can be used in nuclear medicine to visualize areas of reduced blood flow in conjunction with physiological or pharmacological stress. Thallium may also be used to determine viability of tissue, distinguishing whether nonfunctional myocardium is actually dead or merely in a state of hibernation or of being stunned. Medical societies and professional guidelines recommend that the physician confirm a person is at high risk for myocardial infarction before conducting imaging tests to make a diagnosis. Patients who have a normal ECG and who are able to exercise, for example, do not merit routine imaging. Imaging tests such as stress radionuclide myocardial perfusion imaging or stress echocardiography can confirm a diagnosis when a patient's history, physical exam, ECG, and cardiac biomarkers suggest the likelihood of a problem.
A patient does not need routine imaging when they have what kind of biomarker?
{ "text": [], "answer_start": [] }
5a6bb40d4eec6b001a80a4fc
Myocardial_infarction
There is some controversy surrounding the effect of dietary fat on the development of cardiovascular disease. People are often advised to keep a diet where less than 30% of the energy intake derives from fat, a diet that contains less than 7% of the energy intake in the form of saturated fat, and a diet that contains less than 300 mg/day of cholesterol. Replacing saturated with mono- polyunsaturated fat is also recommended, as the consumption of polyunsaturated fat instead of saturated fat may decrease coronary heart disease. Olive oil, rapeseed oil and related products are to be used instead of saturated fat.
How many mg of fat is suggested for a healthy person's diet?
{ "text": [], "answer_start": [] }
5a6bb40d4eec6b001a80a4fd
Myocardial_infarction
There is some controversy surrounding the effect of dietary fat on the development of cardiovascular disease. People are often advised to keep a diet where less than 30% of the energy intake derives from fat, a diet that contains less than 7% of the energy intake in the form of saturated fat, and a diet that contains less than 300 mg/day of cholesterol. Replacing saturated with mono- polyunsaturated fat is also recommended, as the consumption of polyunsaturated fat instead of saturated fat may decrease coronary heart disease. Olive oil, rapeseed oil and related products are to be used instead of saturated fat.
What percentage of mono-polyunsaturated fat should make up a person's daily energy requirements?
{ "text": [], "answer_start": [] }
5a6bb40d4eec6b001a80a4fe
Myocardial_infarction
There is some controversy surrounding the effect of dietary fat on the development of cardiovascular disease. People are often advised to keep a diet where less than 30% of the energy intake derives from fat, a diet that contains less than 7% of the energy intake in the form of saturated fat, and a diet that contains less than 300 mg/day of cholesterol. Replacing saturated with mono- polyunsaturated fat is also recommended, as the consumption of polyunsaturated fat instead of saturated fat may decrease coronary heart disease. Olive oil, rapeseed oil and related products are to be used instead of saturated fat.
What is a good replacement for olive oil?
{ "text": [], "answer_start": [] }
5a6bb40d4eec6b001a80a4ff
Myocardial_infarction
There is some controversy surrounding the effect of dietary fat on the development of cardiovascular disease. People are often advised to keep a diet where less than 30% of the energy intake derives from fat, a diet that contains less than 7% of the energy intake in the form of saturated fat, and a diet that contains less than 300 mg/day of cholesterol. Replacing saturated with mono- polyunsaturated fat is also recommended, as the consumption of polyunsaturated fat instead of saturated fat may decrease coronary heart disease. Olive oil, rapeseed oil and related products are to be used instead of saturated fat.
Nutritionists recommend an intake of more than 30% of what in one's diet?
{ "text": [], "answer_start": [] }
5a6bb40d4eec6b001a80a500
Myocardial_infarction
There is some controversy surrounding the effect of dietary fat on the development of cardiovascular disease. People are often advised to keep a diet where less than 30% of the energy intake derives from fat, a diet that contains less than 7% of the energy intake in the form of saturated fat, and a diet that contains less than 300 mg/day of cholesterol. Replacing saturated with mono- polyunsaturated fat is also recommended, as the consumption of polyunsaturated fat instead of saturated fat may decrease coronary heart disease. Olive oil, rapeseed oil and related products are to be used instead of saturated fat.
What controversy have dieticians largely settled?
{ "text": [], "answer_start": [] }
5a6bb4fa4eec6b001a80a506
Myocardial_infarction
Aspirin has been studied extensively in people considered at increased risk of myocardial infarction. Based on numerous studies in different groups (e.g. people with or without diabetes), there does not appear to be a benefit strong enough to outweigh the risk of excessive bleeding. Nevertheless, many clinical practice guidelines continue to recommend aspirin for primary prevention, and some researchers feel that those with very high cardiovascular risk but low risk of bleeding should continue to receive aspirin.
What drug has been shown to have significant benefits for people at risk of an MI?
{ "text": [], "answer_start": [] }
5a6bb4fa4eec6b001a80a507
Myocardial_infarction
Aspirin has been studied extensively in people considered at increased risk of myocardial infarction. Based on numerous studies in different groups (e.g. people with or without diabetes), there does not appear to be a benefit strong enough to outweigh the risk of excessive bleeding. Nevertheless, many clinical practice guidelines continue to recommend aspirin for primary prevention, and some researchers feel that those with very high cardiovascular risk but low risk of bleeding should continue to receive aspirin.
Most studies tend to focus on people with what disease?
{ "text": [], "answer_start": [] }
5a6bb4fa4eec6b001a80a508
Myocardial_infarction
Aspirin has been studied extensively in people considered at increased risk of myocardial infarction. Based on numerous studies in different groups (e.g. people with or without diabetes), there does not appear to be a benefit strong enough to outweigh the risk of excessive bleeding. Nevertheless, many clinical practice guidelines continue to recommend aspirin for primary prevention, and some researchers feel that those with very high cardiovascular risk but low risk of bleeding should continue to receive aspirin.
People with diabetes have an increased likelihood of what side effect?
{ "text": [], "answer_start": [] }
5a6bb4fa4eec6b001a80a509
Myocardial_infarction
Aspirin has been studied extensively in people considered at increased risk of myocardial infarction. Based on numerous studies in different groups (e.g. people with or without diabetes), there does not appear to be a benefit strong enough to outweigh the risk of excessive bleeding. Nevertheless, many clinical practice guidelines continue to recommend aspirin for primary prevention, and some researchers feel that those with very high cardiovascular risk but low risk of bleeding should continue to receive aspirin.
Based on the lack of benefits, what has largely stopped recommending asprin?
{ "text": [], "answer_start": [] }
5a6bb4fa4eec6b001a80a50a
Myocardial_infarction
Aspirin has been studied extensively in people considered at increased risk of myocardial infarction. Based on numerous studies in different groups (e.g. people with or without diabetes), there does not appear to be a benefit strong enough to outweigh the risk of excessive bleeding. Nevertheless, many clinical practice guidelines continue to recommend aspirin for primary prevention, and some researchers feel that those with very high cardiovascular risk but low risk of bleeding should continue to receive aspirin.
Aspirin is recommended for people with a high risk both cardiovascular disease and what?
{ "text": [], "answer_start": [] }
5a6bb5ff4eec6b001a80a510
Myocardial_infarction
The main treatment for MI with ECG evidence of ST elevation (STEMI) include thrombolysis and percutaneous coronary intervention. Primary percutaneous coronary intervention (PCI) is the treatment of choice for STEMI if it can be performed in a timely manner. If PCI cannot be performed within 90 to 120 minutes then thrombolysis, preferably within 30 minutes of arrival to hospital, is recommended. If a person has had symptoms for 12 to 24 hours evidence for thrombolysis is less and if they have had symptoms for more than 24 hours it is not recommended.
What is the shortened way of referring to thrombolysis?
{ "text": [], "answer_start": [] }
5a6bb5ff4eec6b001a80a511
Myocardial_infarction
The main treatment for MI with ECG evidence of ST elevation (STEMI) include thrombolysis and percutaneous coronary intervention. Primary percutaneous coronary intervention (PCI) is the treatment of choice for STEMI if it can be performed in a timely manner. If PCI cannot be performed within 90 to 120 minutes then thrombolysis, preferably within 30 minutes of arrival to hospital, is recommended. If a person has had symptoms for 12 to 24 hours evidence for thrombolysis is less and if they have had symptoms for more than 24 hours it is not recommended.
PCI and what treatment must be performed within 90 to 120 minutes?
{ "text": [], "answer_start": [] }
5a6bb5ff4eec6b001a80a512
Myocardial_infarction
The main treatment for MI with ECG evidence of ST elevation (STEMI) include thrombolysis and percutaneous coronary intervention. Primary percutaneous coronary intervention (PCI) is the treatment of choice for STEMI if it can be performed in a timely manner. If PCI cannot be performed within 90 to 120 minutes then thrombolysis, preferably within 30 minutes of arrival to hospital, is recommended. If a person has had symptoms for 12 to 24 hours evidence for thrombolysis is less and if they have had symptoms for more than 24 hours it is not recommended.
How long does the PCI procedure take?
{ "text": [], "answer_start": [] }
5a6bb5ff4eec6b001a80a513
Myocardial_infarction
The main treatment for MI with ECG evidence of ST elevation (STEMI) include thrombolysis and percutaneous coronary intervention. Primary percutaneous coronary intervention (PCI) is the treatment of choice for STEMI if it can be performed in a timely manner. If PCI cannot be performed within 90 to 120 minutes then thrombolysis, preferably within 30 minutes of arrival to hospital, is recommended. If a person has had symptoms for 12 to 24 hours evidence for thrombolysis is less and if they have had symptoms for more than 24 hours it is not recommended.
What treatment is recommended after 24 hours?
{ "text": [], "answer_start": [] }
5a6bb5ff4eec6b001a80a514
Myocardial_infarction
The main treatment for MI with ECG evidence of ST elevation (STEMI) include thrombolysis and percutaneous coronary intervention. Primary percutaneous coronary intervention (PCI) is the treatment of choice for STEMI if it can be performed in a timely manner. If PCI cannot be performed within 90 to 120 minutes then thrombolysis, preferably within 30 minutes of arrival to hospital, is recommended. If a person has had symptoms for 12 to 24 hours evidence for thrombolysis is less and if they have had symptoms for more than 24 hours it is not recommended.
When must ECG evidence be taken?
{ "text": [], "answer_start": [] }
5a6bb82b4eec6b001a80a524
Myocardial_infarction
Thrombolysis involves the administration of medication that activates the enzymes that normally destroy blood clots. Thrombolysis agents include streptokinase, reteplase, alteplase, and tenecteplase. If no contraindications are present (such as a high risk of bleeding), thrombolysis can be given in the pre-hospital or in-hospital setting. When given to people suspected of having a STEMI within 6 hours of the onset of symptoms, thrombolytic drugs save the life of 1 in 43 who received them. The risks were major bleeding (1 in 143) and brain bleeding (1 in 250). It is unclear whether pre-hospital thrombolysis reduces death in people with STEMI compared to in-hospital thrombolysis. Pre-hospital thrombolysis reduces time to thrombolytic treatment, based on studies conducted in higher income countries.
What enzymes in the body typically destroy blood clots?
{ "text": [], "answer_start": [] }
5a6bb82b4eec6b001a80a525
Myocardial_infarction
Thrombolysis involves the administration of medication that activates the enzymes that normally destroy blood clots. Thrombolysis agents include streptokinase, reteplase, alteplase, and tenecteplase. If no contraindications are present (such as a high risk of bleeding), thrombolysis can be given in the pre-hospital or in-hospital setting. When given to people suspected of having a STEMI within 6 hours of the onset of symptoms, thrombolytic drugs save the life of 1 in 43 who received them. The risks were major bleeding (1 in 143) and brain bleeding (1 in 250). It is unclear whether pre-hospital thrombolysis reduces death in people with STEMI compared to in-hospital thrombolysis. Pre-hospital thrombolysis reduces time to thrombolytic treatment, based on studies conducted in higher income countries.
What is an example of a contraindication that must be present for thrombolysis?
{ "text": [], "answer_start": [] }
5a6bb82b4eec6b001a80a526
Myocardial_infarction
Thrombolysis involves the administration of medication that activates the enzymes that normally destroy blood clots. Thrombolysis agents include streptokinase, reteplase, alteplase, and tenecteplase. If no contraindications are present (such as a high risk of bleeding), thrombolysis can be given in the pre-hospital or in-hospital setting. When given to people suspected of having a STEMI within 6 hours of the onset of symptoms, thrombolytic drugs save the life of 1 in 43 who received them. The risks were major bleeding (1 in 143) and brain bleeding (1 in 250). It is unclear whether pre-hospital thrombolysis reduces death in people with STEMI compared to in-hospital thrombolysis. Pre-hospital thrombolysis reduces time to thrombolytic treatment, based on studies conducted in higher income countries.
Thrombolytic drugs are given to how many people?
{ "text": [], "answer_start": [] }
5a6bb82b4eec6b001a80a527
Myocardial_infarction
Thrombolysis involves the administration of medication that activates the enzymes that normally destroy blood clots. Thrombolysis agents include streptokinase, reteplase, alteplase, and tenecteplase. If no contraindications are present (such as a high risk of bleeding), thrombolysis can be given in the pre-hospital or in-hospital setting. When given to people suspected of having a STEMI within 6 hours of the onset of symptoms, thrombolytic drugs save the life of 1 in 43 who received them. The risks were major bleeding (1 in 143) and brain bleeding (1 in 250). It is unclear whether pre-hospital thrombolysis reduces death in people with STEMI compared to in-hospital thrombolysis. Pre-hospital thrombolysis reduces time to thrombolytic treatment, based on studies conducted in higher income countries.
If thrombolytic drugs are given after 6 hours of onset, what are the odds of bleeding?
{ "text": [], "answer_start": [] }
5a6bb82b4eec6b001a80a528
Myocardial_infarction
Thrombolysis involves the administration of medication that activates the enzymes that normally destroy blood clots. Thrombolysis agents include streptokinase, reteplase, alteplase, and tenecteplase. If no contraindications are present (such as a high risk of bleeding), thrombolysis can be given in the pre-hospital or in-hospital setting. When given to people suspected of having a STEMI within 6 hours of the onset of symptoms, thrombolytic drugs save the life of 1 in 43 who received them. The risks were major bleeding (1 in 143) and brain bleeding (1 in 250). It is unclear whether pre-hospital thrombolysis reduces death in people with STEMI compared to in-hospital thrombolysis. Pre-hospital thrombolysis reduces time to thrombolytic treatment, based on studies conducted in higher income countries.
How many hours must pass after onset of symptoms before administering thrombolysis?
{ "text": [], "answer_start": [] }
5a6bb9624eec6b001a80a538
Myocardial_infarction
People with an acute coronary syndrome where no ST elevation is demonstrated (non-ST elevation ACS or NSTEACS) are treated with aspirin. Clopidogrel is added in many cases, particularly if the risk of cardiovascular events is felt to be high and early PCI is being considered. Depending on whether early PCI is planned, a factor Xa inhibitor or a potentiator of antithrombin (fondaparinux or low molecular weight heparin respectively) may be added. In very high-risk scenarios, inhibitors of the platelet glycoprotein αIIbβ3a receptor such as eptifibatide or tirofiban may be used.
When is clopidogrel removed?
{ "text": [], "answer_start": [] }
5a6bb9624eec6b001a80a539
Myocardial_infarction
People with an acute coronary syndrome where no ST elevation is demonstrated (non-ST elevation ACS or NSTEACS) are treated with aspirin. Clopidogrel is added in many cases, particularly if the risk of cardiovascular events is felt to be high and early PCI is being considered. Depending on whether early PCI is planned, a factor Xa inhibitor or a potentiator of antithrombin (fondaparinux or low molecular weight heparin respectively) may be added. In very high-risk scenarios, inhibitors of the platelet glycoprotein αIIbβ3a receptor such as eptifibatide or tirofiban may be used.
What is NSTEACS an abbreviation for?
{ "text": [], "answer_start": [] }
5a6bb9624eec6b001a80a53a
Myocardial_infarction
People with an acute coronary syndrome where no ST elevation is demonstrated (non-ST elevation ACS or NSTEACS) are treated with aspirin. Clopidogrel is added in many cases, particularly if the risk of cardiovascular events is felt to be high and early PCI is being considered. Depending on whether early PCI is planned, a factor Xa inhibitor or a potentiator of antithrombin (fondaparinux or low molecular weight heparin respectively) may be added. In very high-risk scenarios, inhibitors of the platelet glycoprotein αIIbβ3a receptor such as eptifibatide or tirofiban may be used.
Clopidogrel is a form of what inhibitor?
{ "text": [], "answer_start": [] }
5a6bb9624eec6b001a80a53b
Myocardial_infarction
People with an acute coronary syndrome where no ST elevation is demonstrated (non-ST elevation ACS or NSTEACS) are treated with aspirin. Clopidogrel is added in many cases, particularly if the risk of cardiovascular events is felt to be high and early PCI is being considered. Depending on whether early PCI is planned, a factor Xa inhibitor or a potentiator of antithrombin (fondaparinux or low molecular weight heparin respectively) may be added. In very high-risk scenarios, inhibitors of the platelet glycoprotein αIIbβ3a receptor such as eptifibatide or tirofiban may be used.
What inhibitors are used in low-risk scenarios?
{ "text": [], "answer_start": [] }
5a6bb9624eec6b001a80a53c
Myocardial_infarction
People with an acute coronary syndrome where no ST elevation is demonstrated (non-ST elevation ACS or NSTEACS) are treated with aspirin. Clopidogrel is added in many cases, particularly if the risk of cardiovascular events is felt to be high and early PCI is being considered. Depending on whether early PCI is planned, a factor Xa inhibitor or a potentiator of antithrombin (fondaparinux or low molecular weight heparin respectively) may be added. In very high-risk scenarios, inhibitors of the platelet glycoprotein αIIbβ3a receptor such as eptifibatide or tirofiban may be used.
Eptifibatide has what kind of molecular weight?
{ "text": [], "answer_start": [] }
5a6bb9f34eec6b001a80a54c
Myocardial_infarction
Cardiac rehabilitation benefits many who have experienced myocardial infarction, even if there has been substantial heart damage and resultant left ventricular failure; ideally other medical conditions that could interfere with participation should be managed optimally. It should start soon after discharge from hospital. The program may include lifestyle advice, exercise, social support, as well as recommendations about driving, flying, sport participation, stress management, and sexual intercourse.
Cardiac rehabilitation is not an option under what circumstances?
{ "text": [], "answer_start": [] }
5a6bb9f34eec6b001a80a54d
Myocardial_infarction
Cardiac rehabilitation benefits many who have experienced myocardial infarction, even if there has been substantial heart damage and resultant left ventricular failure; ideally other medical conditions that could interfere with participation should be managed optimally. It should start soon after discharge from hospital. The program may include lifestyle advice, exercise, social support, as well as recommendations about driving, flying, sport participation, stress management, and sexual intercourse.
Cardiac rehabilitation often recommends ceasing what activities?
{ "text": [], "answer_start": [] }
5a6bb9f34eec6b001a80a54e
Myocardial_infarction
Cardiac rehabilitation benefits many who have experienced myocardial infarction, even if there has been substantial heart damage and resultant left ventricular failure; ideally other medical conditions that could interfere with participation should be managed optimally. It should start soon after discharge from hospital. The program may include lifestyle advice, exercise, social support, as well as recommendations about driving, flying, sport participation, stress management, and sexual intercourse.
What should start immediately upon registering at the hospital?
{ "text": [], "answer_start": [] }
5a6bb9f34eec6b001a80a54f
Myocardial_infarction
Cardiac rehabilitation benefits many who have experienced myocardial infarction, even if there has been substantial heart damage and resultant left ventricular failure; ideally other medical conditions that could interfere with participation should be managed optimally. It should start soon after discharge from hospital. The program may include lifestyle advice, exercise, social support, as well as recommendations about driving, flying, sport participation, stress management, and sexual intercourse.
When are other medical conditions address?
{ "text": [], "answer_start": [] }
5a6bba8a4eec6b001a80a554
Myocardial_infarction
Some risk factors for death include age, hemodynamic parameters (such as heart failure, cardiac arrest on admission, systolic blood pressure, or Killip class of two or greater), ST-segment deviation, diabetes, serum creatinine, peripheral vascular disease, and elevation of cardiac markers. Assessment of left ventricular ejection fraction may increase the predictive power. Prognosis is worse if a mechanical complication such as papillary muscle or myocardial free wall rupture occurs. Morbidity and mortality from myocardial infarction has improved over the years due to better treatment.
How many classes of ST-segmentation are there?
{ "text": [], "answer_start": [] }
5a6bba8a4eec6b001a80a555
Myocardial_infarction
Some risk factors for death include age, hemodynamic parameters (such as heart failure, cardiac arrest on admission, systolic blood pressure, or Killip class of two or greater), ST-segment deviation, diabetes, serum creatinine, peripheral vascular disease, and elevation of cardiac markers. Assessment of left ventricular ejection fraction may increase the predictive power. Prognosis is worse if a mechanical complication such as papillary muscle or myocardial free wall rupture occurs. Morbidity and mortality from myocardial infarction has improved over the years due to better treatment.
Prognosis improves after what complication?
{ "text": [], "answer_start": [] }
5a6bba8a4eec6b001a80a556
Myocardial_infarction
Some risk factors for death include age, hemodynamic parameters (such as heart failure, cardiac arrest on admission, systolic blood pressure, or Killip class of two or greater), ST-segment deviation, diabetes, serum creatinine, peripheral vascular disease, and elevation of cardiac markers. Assessment of left ventricular ejection fraction may increase the predictive power. Prognosis is worse if a mechanical complication such as papillary muscle or myocardial free wall rupture occurs. Morbidity and mortality from myocardial infarction has improved over the years due to better treatment.
What has decreased over the years?
{ "text": [], "answer_start": [] }
5a6bba8a4eec6b001a80a557
Myocardial_infarction
Some risk factors for death include age, hemodynamic parameters (such as heart failure, cardiac arrest on admission, systolic blood pressure, or Killip class of two or greater), ST-segment deviation, diabetes, serum creatinine, peripheral vascular disease, and elevation of cardiac markers. Assessment of left ventricular ejection fraction may increase the predictive power. Prognosis is worse if a mechanical complication such as papillary muscle or myocardial free wall rupture occurs. Morbidity and mortality from myocardial infarction has improved over the years due to better treatment.
What are some examples of ST-segment deviation?
{ "text": [], "answer_start": [] }
5a6bba8a4eec6b001a80a558
Myocardial_infarction
Some risk factors for death include age, hemodynamic parameters (such as heart failure, cardiac arrest on admission, systolic blood pressure, or Killip class of two or greater), ST-segment deviation, diabetes, serum creatinine, peripheral vascular disease, and elevation of cardiac markers. Assessment of left ventricular ejection fraction may increase the predictive power. Prognosis is worse if a mechanical complication such as papillary muscle or myocardial free wall rupture occurs. Morbidity and mortality from myocardial infarction has improved over the years due to better treatment.
What are risk factors called?
{ "text": [], "answer_start": [] }
5a6bbb724eec6b001a80a55e
Myocardial_infarction
Complications may occur immediately following the heart attack (in the acute phase), or may need time to develop (a chronic problem). Acute complications may include heart failure if the damaged heart is no longer able to pump blood adequately around the body; aneurysm of the left ventricle myocardium; ventricular septal rupture or free wall rupture; mitral regurgitation, in particular if the infarction causes dysfunction of the papillary muscle; Dressler's syndrome; and abnormal heart rhythms, such as ventricular fibrillation, ventricular tachycardia, atrial fibrillation, and heart block. Longer-term complications include heart failure, atrial fibrillation, and an increased risk of a second MI.
What is Dressler's syndrome?
{ "text": [], "answer_start": [] }
5a6bbb724eec6b001a80a55f
Myocardial_infarction
Complications may occur immediately following the heart attack (in the acute phase), or may need time to develop (a chronic problem). Acute complications may include heart failure if the damaged heart is no longer able to pump blood adequately around the body; aneurysm of the left ventricle myocardium; ventricular septal rupture or free wall rupture; mitral regurgitation, in particular if the infarction causes dysfunction of the papillary muscle; Dressler's syndrome; and abnormal heart rhythms, such as ventricular fibrillation, ventricular tachycardia, atrial fibrillation, and heart block. Longer-term complications include heart failure, atrial fibrillation, and an increased risk of a second MI.
What does an aneurysm of the left ventricle lead to?
{ "text": [], "answer_start": [] }
5a6bbb724eec6b001a80a560
Myocardial_infarction
Complications may occur immediately following the heart attack (in the acute phase), or may need time to develop (a chronic problem). Acute complications may include heart failure if the damaged heart is no longer able to pump blood adequately around the body; aneurysm of the left ventricle myocardium; ventricular septal rupture or free wall rupture; mitral regurgitation, in particular if the infarction causes dysfunction of the papillary muscle; Dressler's syndrome; and abnormal heart rhythms, such as ventricular fibrillation, ventricular tachycardia, atrial fibrillation, and heart block. Longer-term complications include heart failure, atrial fibrillation, and an increased risk of a second MI.
What does mitral regurgitation cause?
{ "text": [], "answer_start": [] }
5a6bbb724eec6b001a80a561
Myocardial_infarction
Complications may occur immediately following the heart attack (in the acute phase), or may need time to develop (a chronic problem). Acute complications may include heart failure if the damaged heart is no longer able to pump blood adequately around the body; aneurysm of the left ventricle myocardium; ventricular septal rupture or free wall rupture; mitral regurgitation, in particular if the infarction causes dysfunction of the papillary muscle; Dressler's syndrome; and abnormal heart rhythms, such as ventricular fibrillation, ventricular tachycardia, atrial fibrillation, and heart block. Longer-term complications include heart failure, atrial fibrillation, and an increased risk of a second MI.
Atrial fibrillation can only be what kind of problem?
{ "text": [], "answer_start": [] }
5a6bbc0f4eec6b001a80a566
Myocardial_infarction
In contrast, IHD is becoming a more common cause of death in the developing world. For example, in India, IHD had become the leading cause of death by 2004, accounting for 1.46 million deaths (14% of total deaths) and deaths due to IHD were expected to double during 1985–2015. Globally, disability adjusted life years (DALYs) lost to ischemic heart disease are predicted to account for 5.5% of total DALYs in 2030, making it the second-most-important cause of disability (after unipolar depressive disorder), as well as the leading cause of death by this date.
What percentage of deaths does unipolar depressive disorder cause?
{ "text": [], "answer_start": [] }
5a6bbc0f4eec6b001a80a567
Myocardial_infarction
In contrast, IHD is becoming a more common cause of death in the developing world. For example, in India, IHD had become the leading cause of death by 2004, accounting for 1.46 million deaths (14% of total deaths) and deaths due to IHD were expected to double during 1985–2015. Globally, disability adjusted life years (DALYs) lost to ischemic heart disease are predicted to account for 5.5% of total DALYs in 2030, making it the second-most-important cause of disability (after unipolar depressive disorder), as well as the leading cause of death by this date.
How many people died from IHD from 1985-2015?
{ "text": [], "answer_start": [] }
5a6bbc0f4eec6b001a80a568
Myocardial_infarction
In contrast, IHD is becoming a more common cause of death in the developing world. For example, in India, IHD had become the leading cause of death by 2004, accounting for 1.46 million deaths (14% of total deaths) and deaths due to IHD were expected to double during 1985–2015. Globally, disability adjusted life years (DALYs) lost to ischemic heart disease are predicted to account for 5.5% of total DALYs in 2030, making it the second-most-important cause of disability (after unipolar depressive disorder), as well as the leading cause of death by this date.
What is the worldwide leading cause of death?
{ "text": [], "answer_start": [] }
5a6bbc0f4eec6b001a80a569
Myocardial_infarction
In contrast, IHD is becoming a more common cause of death in the developing world. For example, in India, IHD had become the leading cause of death by 2004, accounting for 1.46 million deaths (14% of total deaths) and deaths due to IHD were expected to double during 1985–2015. Globally, disability adjusted life years (DALYs) lost to ischemic heart disease are predicted to account for 5.5% of total DALYs in 2030, making it the second-most-important cause of disability (after unipolar depressive disorder), as well as the leading cause of death by this date.
What percentage of deaths will IHD be responsible for in 2030?
{ "text": [], "answer_start": [] }
5a6bbc0f4eec6b001a80a56a
Myocardial_infarction
In contrast, IHD is becoming a more common cause of death in the developing world. For example, in India, IHD had become the leading cause of death by 2004, accounting for 1.46 million deaths (14% of total deaths) and deaths due to IHD were expected to double during 1985–2015. Globally, disability adjusted life years (DALYs) lost to ischemic heart disease are predicted to account for 5.5% of total DALYs in 2030, making it the second-most-important cause of disability (after unipolar depressive disorder), as well as the leading cause of death by this date.
When did IHD begin to be a bigger problem in the developing word?
{ "text": [], "answer_start": [] }
5a6bbd284eec6b001a80a57a
Myocardial_infarction
At common law, in general, a myocardial infarction is a disease, but may sometimes be an injury. This can create coverage issues in administration of no-fault insurance schemes such as workers' compensation. In general, a heart attack is not covered; however, it may be a work-related injury if it results, for example, from unusual emotional stress or unusual exertion. In addition, in some jurisdictions, heart attacks suffered by persons in particular occupations such as police officers may be classified as line-of-duty injuries by statute or policy. In some countries or states, a person having suffered from an MI may be prevented from participating in activity that puts other people's lives at risk, for example driving a car or flying an airplane.
What is a myocardial infarction is always considered to be?
{ "text": [], "answer_start": [] }
5a6bbd284eec6b001a80a57b
Myocardial_infarction
At common law, in general, a myocardial infarction is a disease, but may sometimes be an injury. This can create coverage issues in administration of no-fault insurance schemes such as workers' compensation. In general, a heart attack is not covered; however, it may be a work-related injury if it results, for example, from unusual emotional stress or unusual exertion. In addition, in some jurisdictions, heart attacks suffered by persons in particular occupations such as police officers may be classified as line-of-duty injuries by statute or policy. In some countries or states, a person having suffered from an MI may be prevented from participating in activity that puts other people's lives at risk, for example driving a car or flying an airplane.
What occupation cannot have a heart attack classified as work-related?
{ "text": [], "answer_start": [] }
5a6bbd284eec6b001a80a57c
Myocardial_infarction
At common law, in general, a myocardial infarction is a disease, but may sometimes be an injury. This can create coverage issues in administration of no-fault insurance schemes such as workers' compensation. In general, a heart attack is not covered; however, it may be a work-related injury if it results, for example, from unusual emotional stress or unusual exertion. In addition, in some jurisdictions, heart attacks suffered by persons in particular occupations such as police officers may be classified as line-of-duty injuries by statute or policy. In some countries or states, a person having suffered from an MI may be prevented from participating in activity that puts other people's lives at risk, for example driving a car or flying an airplane.
What typically covers an MI?
{ "text": [], "answer_start": [] }
5a6bbd284eec6b001a80a57d
Myocardial_infarction
At common law, in general, a myocardial infarction is a disease, but may sometimes be an injury. This can create coverage issues in administration of no-fault insurance schemes such as workers' compensation. In general, a heart attack is not covered; however, it may be a work-related injury if it results, for example, from unusual emotional stress or unusual exertion. In addition, in some jurisdictions, heart attacks suffered by persons in particular occupations such as police officers may be classified as line-of-duty injuries by statute or policy. In some countries or states, a person having suffered from an MI may be prevented from participating in activity that puts other people's lives at risk, for example driving a car or flying an airplane.
When is an MI not considered a work-related injury?
{ "text": [], "answer_start": [] }
5a6bbd284eec6b001a80a57e
Myocardial_infarction
At common law, in general, a myocardial infarction is a disease, but may sometimes be an injury. This can create coverage issues in administration of no-fault insurance schemes such as workers' compensation. In general, a heart attack is not covered; however, it may be a work-related injury if it results, for example, from unusual emotional stress or unusual exertion. In addition, in some jurisdictions, heart attacks suffered by persons in particular occupations such as police officers may be classified as line-of-duty injuries by statute or policy. In some countries or states, a person having suffered from an MI may be prevented from participating in activity that puts other people's lives at risk, for example driving a car or flying an airplane.
What generally treats MI as an injury?
{ "text": [], "answer_start": [] }
5a7db48670df9f001a87505f
Matter
Before the 20th century, the term matter included ordinary matter composed of atoms and excluded other energy phenomena such as light or sound. This concept of matter may be generalized from atoms to include any objects having mass even when at rest, but this is ill-defined because an object's mass can arise from its (possibly massless) constituents' motion and interaction energies. Thus, matter does not have a universal definition, nor is it a fundamental concept in physics today. Matter is also used loosely as a general term for the substance that makes up all observable physical objects.
What did the term matter include after the 20th century?
{ "text": [], "answer_start": [] }
5a7db48670df9f001a875060
Matter
Before the 20th century, the term matter included ordinary matter composed of atoms and excluded other energy phenomena such as light or sound. This concept of matter may be generalized from atoms to include any objects having mass even when at rest, but this is ill-defined because an object's mass can arise from its (possibly massless) constituents' motion and interaction energies. Thus, matter does not have a universal definition, nor is it a fundamental concept in physics today. Matter is also used loosely as a general term for the substance that makes up all observable physical objects.
What are atoms composed of?
{ "text": [], "answer_start": [] }
5a7db48670df9f001a875061
Matter
Before the 20th century, the term matter included ordinary matter composed of atoms and excluded other energy phenomena such as light or sound. This concept of matter may be generalized from atoms to include any objects having mass even when at rest, but this is ill-defined because an object's mass can arise from its (possibly massless) constituents' motion and interaction energies. Thus, matter does not have a universal definition, nor is it a fundamental concept in physics today. Matter is also used loosely as a general term for the substance that makes up all observable physical objects.
What are two examples of matter?
{ "text": [], "answer_start": [] }
5a7db48670df9f001a875062
Matter
Before the 20th century, the term matter included ordinary matter composed of atoms and excluded other energy phenomena such as light or sound. This concept of matter may be generalized from atoms to include any objects having mass even when at rest, but this is ill-defined because an object's mass can arise from its (possibly massless) constituents' motion and interaction energies. Thus, matter does not have a universal definition, nor is it a fundamental concept in physics today. Matter is also used loosely as a general term for the substance that makes up all observable physical objects.
What can an object's mass not come from?
{ "text": [], "answer_start": [] }
5a7db48670df9f001a875063
Matter
Before the 20th century, the term matter included ordinary matter composed of atoms and excluded other energy phenomena such as light or sound. This concept of matter may be generalized from atoms to include any objects having mass even when at rest, but this is ill-defined because an object's mass can arise from its (possibly massless) constituents' motion and interaction energies. Thus, matter does not have a universal definition, nor is it a fundamental concept in physics today. Matter is also used loosely as a general term for the substance that makes up all observable physical objects.
Matter is currently considered to be what kind of concept?
{ "text": [], "answer_start": [] }
5a7db5c270df9f001a875069
Matter
All the objects from everyday life that we can bump into, touch or squeeze are composed of atoms. This atomic matter is in turn made up of interacting subatomic particles—usually a nucleus of protons and neutrons, and a cloud of orbiting electrons. Typically, science considers these composite particles matter because they have both rest mass and volume. By contrast, massless particles, such as photons, are not considered matter, because they have neither rest mass nor volume. However, not all particles with rest mass have a classical volume, since fundamental particles such as quarks and leptons (sometimes equated with matter) are considered "point particles" with no effective size or volume. Nevertheless, quarks and leptons together make up "ordinary matter", and their interactions contribute to the effective volume of the composite particles that make up ordinary matter.
What orbits around electrons?
{ "text": [], "answer_start": [] }
5a7db5c270df9f001a87506a
Matter
All the objects from everyday life that we can bump into, touch or squeeze are composed of atoms. This atomic matter is in turn made up of interacting subatomic particles—usually a nucleus of protons and neutrons, and a cloud of orbiting electrons. Typically, science considers these composite particles matter because they have both rest mass and volume. By contrast, massless particles, such as photons, are not considered matter, because they have neither rest mass nor volume. However, not all particles with rest mass have a classical volume, since fundamental particles such as quarks and leptons (sometimes equated with matter) are considered "point particles" with no effective size or volume. Nevertheless, quarks and leptons together make up "ordinary matter", and their interactions contribute to the effective volume of the composite particles that make up ordinary matter.
What are protons and neutrons made out of?
{ "text": [], "answer_start": [] }
5a7db5c270df9f001a87506b
Matter
All the objects from everyday life that we can bump into, touch or squeeze are composed of atoms. This atomic matter is in turn made up of interacting subatomic particles—usually a nucleus of protons and neutrons, and a cloud of orbiting electrons. Typically, science considers these composite particles matter because they have both rest mass and volume. By contrast, massless particles, such as photons, are not considered matter, because they have neither rest mass nor volume. However, not all particles with rest mass have a classical volume, since fundamental particles such as quarks and leptons (sometimes equated with matter) are considered "point particles" with no effective size or volume. Nevertheless, quarks and leptons together make up "ordinary matter", and their interactions contribute to the effective volume of the composite particles that make up ordinary matter.
All particles with rest mass have what kind of volume?
{ "text": [], "answer_start": [] }
5a7db5c270df9f001a87506c
Matter
All the objects from everyday life that we can bump into, touch or squeeze are composed of atoms. This atomic matter is in turn made up of interacting subatomic particles—usually a nucleus of protons and neutrons, and a cloud of orbiting electrons. Typically, science considers these composite particles matter because they have both rest mass and volume. By contrast, massless particles, such as photons, are not considered matter, because they have neither rest mass nor volume. However, not all particles with rest mass have a classical volume, since fundamental particles such as quarks and leptons (sometimes equated with matter) are considered "point particles" with no effective size or volume. Nevertheless, quarks and leptons together make up "ordinary matter", and their interactions contribute to the effective volume of the composite particles that make up ordinary matter.
What cannot contribute to effective volume?
{ "text": [], "answer_start": [] }
5a7db5c270df9f001a87506d
Matter
All the objects from everyday life that we can bump into, touch or squeeze are composed of atoms. This atomic matter is in turn made up of interacting subatomic particles—usually a nucleus of protons and neutrons, and a cloud of orbiting electrons. Typically, science considers these composite particles matter because they have both rest mass and volume. By contrast, massless particles, such as photons, are not considered matter, because they have neither rest mass nor volume. However, not all particles with rest mass have a classical volume, since fundamental particles such as quarks and leptons (sometimes equated with matter) are considered "point particles" with no effective size or volume. Nevertheless, quarks and leptons together make up "ordinary matter", and their interactions contribute to the effective volume of the composite particles that make up ordinary matter.
What kind of size or volume do point particles have?
{ "text": [], "answer_start": [] }
5a7db6b770df9f001a875073
Matter
Matter commonly exists in four states (or phases): solid, liquid and gas, and plasma. However, advances in experimental techniques have revealed other previously theoretical phases, such as Bose–Einstein condensates and fermionic condensates. A focus on an elementary-particle view of matter also leads to new phases of matter, such as the quark–gluon plasma. For much of the history of the natural sciences people have contemplated the exact nature of matter. The idea that matter was built of discrete building blocks, the so-called particulate theory of matter, was first put forward by the Greek philosophers Leucippus (~490 BC) and Democritus (~470–380 BC).
How many forms of solids are there?
{ "text": [], "answer_start": [] }
5a7db6b770df9f001a875074
Matter
Matter commonly exists in four states (or phases): solid, liquid and gas, and plasma. However, advances in experimental techniques have revealed other previously theoretical phases, such as Bose–Einstein condensates and fermionic condensates. A focus on an elementary-particle view of matter also leads to new phases of matter, such as the quark–gluon plasma. For much of the history of the natural sciences people have contemplated the exact nature of matter. The idea that matter was built of discrete building blocks, the so-called particulate theory of matter, was first put forward by the Greek philosophers Leucippus (~490 BC) and Democritus (~470–380 BC).
What theory states that matter can exist in four states?
{ "text": [], "answer_start": [] }
5a7db6b770df9f001a875075
Matter
Matter commonly exists in four states (or phases): solid, liquid and gas, and plasma. However, advances in experimental techniques have revealed other previously theoretical phases, such as Bose–Einstein condensates and fermionic condensates. A focus on an elementary-particle view of matter also leads to new phases of matter, such as the quark–gluon plasma. For much of the history of the natural sciences people have contemplated the exact nature of matter. The idea that matter was built of discrete building blocks, the so-called particulate theory of matter, was first put forward by the Greek philosophers Leucippus (~490 BC) and Democritus (~470–380 BC).
Who suggested the Bose-Einstein theory?
{ "text": [], "answer_start": [] }
5a7db6b770df9f001a875076
Matter
Matter commonly exists in four states (or phases): solid, liquid and gas, and plasma. However, advances in experimental techniques have revealed other previously theoretical phases, such as Bose–Einstein condensates and fermionic condensates. A focus on an elementary-particle view of matter also leads to new phases of matter, such as the quark–gluon plasma. For much of the history of the natural sciences people have contemplated the exact nature of matter. The idea that matter was built of discrete building blocks, the so-called particulate theory of matter, was first put forward by the Greek philosophers Leucippus (~490 BC) and Democritus (~470–380 BC).
What new form of plasma did Democritus discover?
{ "text": [], "answer_start": [] }
5a7db6b770df9f001a875077
Matter
Matter commonly exists in four states (or phases): solid, liquid and gas, and plasma. However, advances in experimental techniques have revealed other previously theoretical phases, such as Bose–Einstein condensates and fermionic condensates. A focus on an elementary-particle view of matter also leads to new phases of matter, such as the quark–gluon plasma. For much of the history of the natural sciences people have contemplated the exact nature of matter. The idea that matter was built of discrete building blocks, the so-called particulate theory of matter, was first put forward by the Greek philosophers Leucippus (~490 BC) and Democritus (~470–380 BC).
How long have scientists focused on an elementary-particle view?
{ "text": [], "answer_start": [] }
5a7db77770df9f001a87507d
Matter
Matter should not be confused with mass, as the two are not quite the same in modern physics. For example, mass is a conserved quantity, which means that its value is unchanging through time, within closed systems. However, matter is not conserved in such systems, although this is not obvious in ordinary conditions on Earth, where matter is approximately conserved. Still, special relativity shows that matter may disappear by conversion into energy, even inside closed systems, and it can also be created from energy, within such systems. However, because mass (like energy) can neither be created nor destroyed, the quantity of mass and the quantity of energy remain the same during a transformation of matter (which represents a certain amount of energy) into non-material (i.e., non-matter) energy. This is also true in the reverse transformation of energy into matter.
What is considered the same as matter?
{ "text": [], "answer_start": [] }
5a7db77770df9f001a87507e
Matter
Matter should not be confused with mass, as the two are not quite the same in modern physics. For example, mass is a conserved quantity, which means that its value is unchanging through time, within closed systems. However, matter is not conserved in such systems, although this is not obvious in ordinary conditions on Earth, where matter is approximately conserved. Still, special relativity shows that matter may disappear by conversion into energy, even inside closed systems, and it can also be created from energy, within such systems. However, because mass (like energy) can neither be created nor destroyed, the quantity of mass and the quantity of energy remain the same during a transformation of matter (which represents a certain amount of energy) into non-material (i.e., non-matter) energy. This is also true in the reverse transformation of energy into matter.
What does special relativity show mass can do?
{ "text": [], "answer_start": [] }
5a7db77770df9f001a87507f
Matter
Matter should not be confused with mass, as the two are not quite the same in modern physics. For example, mass is a conserved quantity, which means that its value is unchanging through time, within closed systems. However, matter is not conserved in such systems, although this is not obvious in ordinary conditions on Earth, where matter is approximately conserved. Still, special relativity shows that matter may disappear by conversion into energy, even inside closed systems, and it can also be created from energy, within such systems. However, because mass (like energy) can neither be created nor destroyed, the quantity of mass and the quantity of energy remain the same during a transformation of matter (which represents a certain amount of energy) into non-material (i.e., non-matter) energy. This is also true in the reverse transformation of energy into matter.
What can be created or destroyed?
{ "text": [], "answer_start": [] }
5a7db77770df9f001a875080
Matter
Matter should not be confused with mass, as the two are not quite the same in modern physics. For example, mass is a conserved quantity, which means that its value is unchanging through time, within closed systems. However, matter is not conserved in such systems, although this is not obvious in ordinary conditions on Earth, where matter is approximately conserved. Still, special relativity shows that matter may disappear by conversion into energy, even inside closed systems, and it can also be created from energy, within such systems. However, because mass (like energy) can neither be created nor destroyed, the quantity of mass and the quantity of energy remain the same during a transformation of matter (which represents a certain amount of energy) into non-material (i.e., non-matter) energy. This is also true in the reverse transformation of energy into matter.
What changes during the transformation of matter?
{ "text": [], "answer_start": [] }
5a7db77770df9f001a875081
Matter
Matter should not be confused with mass, as the two are not quite the same in modern physics. For example, mass is a conserved quantity, which means that its value is unchanging through time, within closed systems. However, matter is not conserved in such systems, although this is not obvious in ordinary conditions on Earth, where matter is approximately conserved. Still, special relativity shows that matter may disappear by conversion into energy, even inside closed systems, and it can also be created from energy, within such systems. However, because mass (like energy) can neither be created nor destroyed, the quantity of mass and the quantity of energy remain the same during a transformation of matter (which represents a certain amount of energy) into non-material (i.e., non-matter) energy. This is also true in the reverse transformation of energy into matter.
What does not change in an open system?
{ "text": [], "answer_start": [] }
5a7db7f770df9f001a875087
Matter
Different fields of science use the term matter in different, and sometimes incompatible, ways. Some of these ways are based on loose historical meanings, from a time when there was no reason to distinguish mass and matter. As such, there is no single universally agreed scientific meaning of the word "matter". Scientifically, the term "mass" is well-defined, but "matter" is not. Sometimes in the field of physics "matter" is simply equated with particles that exhibit rest mass (i.e., that cannot travel at the speed of light), such as quarks and leptons. However, in both physics and chemistry, matter exhibits both wave-like and particle-like properties, the so-called wave–particle duality.
What is always used the same way across fields?
{ "text": [], "answer_start": [] }
5a7db7f770df9f001a875088
Matter
Different fields of science use the term matter in different, and sometimes incompatible, ways. Some of these ways are based on loose historical meanings, from a time when there was no reason to distinguish mass and matter. As such, there is no single universally agreed scientific meaning of the word "matter". Scientifically, the term "mass" is well-defined, but "matter" is not. Sometimes in the field of physics "matter" is simply equated with particles that exhibit rest mass (i.e., that cannot travel at the speed of light), such as quarks and leptons. However, in both physics and chemistry, matter exhibits both wave-like and particle-like properties, the so-called wave–particle duality.
What is poorly defined besides matter?
{ "text": [], "answer_start": [] }
5a7db7f770df9f001a875089
Matter
Different fields of science use the term matter in different, and sometimes incompatible, ways. Some of these ways are based on loose historical meanings, from a time when there was no reason to distinguish mass and matter. As such, there is no single universally agreed scientific meaning of the word "matter". Scientifically, the term "mass" is well-defined, but "matter" is not. Sometimes in the field of physics "matter" is simply equated with particles that exhibit rest mass (i.e., that cannot travel at the speed of light), such as quarks and leptons. However, in both physics and chemistry, matter exhibits both wave-like and particle-like properties, the so-called wave–particle duality.
What does matter do in chemistry that it does not do in physics?
{ "text": [], "answer_start": [] }