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[A quantitative and qualitative study on effective information flow for infectious disease control in welfare facilities for the elderly]. | health-related information; and factors associated with information flows. Summarized codes were extracted from the transcriptions from tape recording and were categorized repeatedly according to similarity.In the questionnaire survey; differences of Community information flow by types of facilities and professional backgrounds were found. Variation was detected in measures for information gathering and focuses in information management between managers/chief practitioners and practitioners. Practitioners | 15682823 | [
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[A quantitative and qualitative study on effective information flow for infectious disease control in welfare facilities for the elderly]. | wanted opportunities for information exchange while managers/chief practitioners mainly focused on prioritization of information collected. In addition; many respondents felt that information networks outside the facilities were poorly organized. From the interview survey; three major categories were extracted; that is; 'Information flow system;' 'Personal qualification;' and 'Factors related to the information flow system.' As factors related to the information flow system; the following 7 subcategories we | 15682823 | [
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[A quantitative and qualitative study on effective information flow for infectious disease control in welfare facilities for the elderly]. | re extracted. 1. Interest in information; 2. Working style and workload; 3. Information networks outside the facility; 4. Information management in the facility; 5. Environment for information sharing; 6. Budget for the information system; and 7. Interpersonal communication.For an effective information system; welfare facilities for the elderly should work on staff training; building their own information flow systems and improving the environment for information sharing and networking with specialized agen | 15682823 | [
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[A quantitative and qualitative study on effective information flow for infectious disease control in welfare facilities for the elderly]. | cies; such as public health centers. At the same time; public health centers should support networking; interpersonal two-way communication and training of welfare-facility workers. | 15682823 | [
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Immunocytochemical localization of beta2-adrenergic receptors in the rat spinal cord and their spatial relationships to tyrosine hydroxylase-immunoreactive terminals. | The distribution of beta2-adrenergic receptors (beta2-ARs) in the rat spinal cord was investigated by immunocytochemistry using an antibody against beta2-ARs. The relationship between beta2-ARs and catecholaminergic terminals containing the catecholamine synthesizing enzyme; tyrosine hydroxylase (TH); in the dorsal horn was also examined by light and electron microscopy. beta2-AR-immunoreactivity (beta2-AR-IR) showing the appearance of fibers and puncta was particularly dense in laminae I and II of the dors | 15682824 | [
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Immunocytochemical localization of beta2-adrenergic receptors in the rat spinal cord and their spatial relationships to tyrosine hydroxylase-immunoreactive terminals. | al horn. Moderate immunoreactivity was observed in the intermediolateral cell column; in the ventral horn and around the central canal. Additional immunoreactivity was detected in ependyma lining the central canal. Capsaicin treatment reduced; but did not eliminate; the immunostaining in the dorsal horn. Double immunofluorescence histochemistry for beta2-AR and TH showed no colocalization of the two antigens. By electron microscopy; beta2-AR-IR was found in dendrites as well as unmyelinated axons and axon t | 15682824 | [
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Immunocytochemical localization of beta2-adrenergic receptors in the rat spinal cord and their spatial relationships to tyrosine hydroxylase-immunoreactive terminals. | erminals which contained many small clear vesicles and several large granular vesicles. Such terminals usually formed asymmetric synapses on labeled or unlabeled dendrites. TH-labeled terminals were often near both axonal and dendritic profiles containing beta2-AR-IR and sometimes made synaptic contacts with beta2-AR-labeled dendrites. However; beta2-AR-IR was found on the extrasynaptic portion of the plasma membrane. No synaptic contact was made between TH-labeled terminals and beta2-AR-labeled varicositie | 15682824 | [
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Immunocytochemical localization of beta2-adrenergic receptors in the rat spinal cord and their spatial relationships to tyrosine hydroxylase-immunoreactive terminals. | s. These results demonstrated that beta2-ARs are localized on both nociceptive primary afferents and on dendrites in the rat dorsal horn and provide the ultrastructural evidence that beta2-ARs on both axonal and dendritic profiles are activated by catecholamines released from catecholaminergic terminals via volume transmission. | 15682824 | [
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Effects of milnacipran on the inhibitory postsynaptic potential in neurons of the rat locus coeruleus. | Effects of milnacipran (MIL); a serotonin and noradrenaline reuptake inhibitor (SNRI); on synaptic transmission were examined in the rat locus coeruleus (LC). Bath-application of MIL produced a hyperpolarization associated with a decrease in input resistance of LC neurons. The MIL-induced hyperpolarization reversed polarity near the equilibrium potential of K+. The MIL-induced hyperpolarization was blocked by yohimbine (1 microM). Clonidine; but not serotonin (5-hydroxytryptamine; 5-HT); produced a hyperpol | 15682825 | [
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Effects of milnacipran on the inhibitory postsynaptic potential in neurons of the rat locus coeruleus. | arizing potential in LC neurons. The MIL-induced hyperpolarization reversed polarity at -114 +/- 3 mV (n=4). MIL (0.1-10 microM) depressed the amplitude of the excitatory postsynaptic potential (EPSP); while it enhanced the amplitude and duration of the inhibitory postsynaptic potential (IPSP). These results suggest that MIL hyperpolarizes LC neurons and enhances the IPSP by increasing endogenous noradrenaline (NA) concentration at synapses in LC neurons. | 15682825 | [
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Immunohistochemical localization of glial cell line-derived neurotrophic factor and its receptor Ret in the rat sweat gland. | Glial cell line-derived neurotrophic factor (GDNF) was initially identified as a neurotrophic factor for dopaminergic neurons but its effects are not restricted to nervous tissue. It is reported that GDNF-induced intercellular signaling is necessary for the normal development of a variety of non-neural tissues. In this study; immunoreactivities of both GDNF and its functional receptor Ret were evaluated in normal adult rat sweat gland by light and electron microscopy. Ret was found in the epithelial cells o | 15682826 | [
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Immunohistochemical localization of glial cell line-derived neurotrophic factor and its receptor Ret in the rat sweat gland. | f the excretory duct and the coiled secretory terminal of the sweat gland. Electron microscopic observation of the secretory epithelium showed that Ret immunoreactivity is localized in the basal area of the secretory cells; facing myoepithelial cells; but it was not observed in the basal infolding or in the apical region of these cells. On the other hand; GDNF was observed in most myoepithelial cells of the coiled secretory portion of the sweat gland and in a small number of nerve fibers innervating the gla | 15682826 | [
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Immunohistochemical localization of glial cell line-derived neurotrophic factor and its receptor Ret in the rat sweat gland. | nd. Although the GDNF-containing nerve fibers cannot be negated as a source of the ligand for Ret in the secretory cells; the finding that GDNF and Ret are localized face to face in adjoining cells in the sweat gland implies another novel trophic role of GDNF in this tissue. | 15682826 | [
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Vertebral deformities in female patients with osteoporosis: influence of trauma and bone mineral density. | Aging societies have an increased incidence of fractures caused by osteoporosis. Vertebral compression fractures occur most frequently in the thoracolumbar vertebrae of elderly individuals. The severe pain caused by this type of fracture causes many patients to become bedridden. However; the initial pain generally diminishes after around 1 month and is replaced by dull pain in the lumbar and lumbosacral regions. We carried out a cross-sectional and longitudinal study of these fractures in 328 female outpati | 15682827 | [
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Vertebral deformities in female patients with osteoporosis: influence of trauma and bone mineral density. | ents with osteoporosis. All subjects initially presented at our hospital with back pain and bone mineral density measurements were taken using both dual energy X-ray absorptiometry and quantitative computed tomography. Our main findings were as follows. Decreased BMD appears to be one cause of vertebral body deformities. However; we found it difficult to predict whether deformities will progress or cause additional deformities of adjacent vertebral bodies; because the key contributing factors include not on | 15682827 | [
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Vertebral deformities in female patients with osteoporosis: influence of trauma and bone mineral density. | ly BMD and age but also lifestyle and activity patterns. In addition; none of the drug administration methods investigated here resulted in a notable increase in BMD. | 15682827 | [
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Immunohistochemical expression of matrix metalloproteinases in bile duct cancer tissue. | In the present study we have examined the immunohistochemical expression of matrix metalloproteinases (MMPs) in bile duct cancer tissue and the relationship between MMP expression and various clinicopathologic factors. We performed immunohistochemical studies of matrix metalloproteinase-2 (MMP2); and matrix metalloproteinase-3 (MMP3). MMP2 and MMP3 were expressed in 48.9% (23/47) and 44.7% (21/47) of the subjects; respectively. Subjects positive for MMP2 showed significantly higher association rates of MMP3 | 15682828 | [
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Immunohistochemical expression of matrix metalloproteinases in bile duct cancer tissue. | expression than those who were not (p<0.05). MMP2 expression was also significantly higher in the group with histologically well-differentiated lesions than in the group with poorly differentiated lesions (p<0.05). Expression of MM2 and MM3 was significantly higher in subjects with neural invasion (p<0.05). The MMP2-negative group had a significantly better prognosis than the MMP2-positive group (p<0.05). MMP2 expression tended to increase as the degree of differentiation decreased; and this indicated a po | 15682828 | [
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Immunohistochemical expression of matrix metalloproteinases in bile duct cancer tissue. | ssibility that MMP2 and MMP3 may be involved in the development of perineural invasion in bile duct cancer. Perineural invasion is an important prognostic factor in bile duct cancer; and the fact that various types of cytokines are involved in the activation of MMPs suggested that bile duct cancer complicated by obstructive cholangitis might be associated with a poorer prognosis. | 15682828 | [
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Gene therapy for murine lung cancer using an adenoviral vector expressing interleukin-15. | It has been proven that interleukin-15 (IL-15) has structural and functional features similar to those of interleukin-2 (IL-2). In this study we examined the anti-tumor effect of IL-15 using an adenoviral vector in a mouse model. We constructed an adenoviral vector expressing the IL-15 gene; and introduced it into a mouse Lewis lung carcinoma (LLC) cell line. Then we inoculated pulmonary tissue of a syngeneic mouse strain (C57BL/6 CR) with the IL-15 gene-expressing LLC cells (LLC/IL-15). At the early phase | 15682829 | [
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Gene therapy for murine lung cancer using an adenoviral vector expressing interleukin-15. | (Day 14); a large number of NK cells accumulated around the IL-15 expressing tumors. At the late phase (Day 28); a much larger number of NK cells had accumulated around the tumors and quite a few NK cells had invaded the IL-15 expressing tumors. The LLC/IL-15-inoculated group survived significantly longer compared to the control groups; i.e.; a group inoculated with LacZ gene-expressing LLC cells or a group inoculated with IL-2 gene-expressing LLC cells. After 60 days; the surviving mice of the LLC/IL-15-in | 15682829 | [
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Gene therapy for murine lung cancer using an adenoviral vector expressing interleukin-15. | oculated group were re-challenged with an additional inoculation of LLC cells alone. Tumor growth was significantly inhibited in the rechallenged LLC/IL-15 group. Induction of cytotoxic T cells was confirmed by interferon-gamma production by splenocytes. We concluded that the IL-15 expressed in the IL-15 expressing tumor cells enhanced the accumulation of NK cells and activated them; leading to suppression of proliferation of the tumor cells. | 15682829 | [
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Transforming growth factor-beta1 expression and the role of angiotensin-converting enzyme inhibitor on perianastomotic intimal hyperplasia in polytetrafluoroethylene graft implanted in rabbit carotid artery. | The purpose of this study was to evaluate the relationship between intimal hyperplasia and transforming growth factor-beta1 (TGF-beta1) mRNA expression in synthetic arterial grafts and also to clarify the effect of angiotensin-converting enzyme inhibitor (ACEI) on perianastomotic intimal hyperplasia and TGF-beta1 mRNA expression. Thirty New Zealand White rabbits were randomly divided into two groups (15 each); one group was administered Captopril 10 mg/kg/day per os as an ACE inhibitor; and the other group | 15682830 | [
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Transforming growth factor-beta1 expression and the role of angiotensin-converting enzyme inhibitor on perianastomotic intimal hyperplasia in polytetrafluoroethylene graft implanted in rabbit carotid artery. | received on saline as a vehicle from 7 days prior to operation until the graft was harvest (1; 8; or 14 weeks). A 10-mm segment of an expanded polytetrafluoroethylene graft (3 mm in diameter) was implanted in the right common carotid artery of the rabbits; 15 rabbits had by-pass grafting alone (Graft Alone group) and the other 15 rabbits had by-pass graft along with the ACEI (Graft plus ACEI group). The artery grafts were harvested. The intima to media height ratio (IMHR) and the TGF-beta1 mRNA expression l | 15682830 | [
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Transforming growth factor-beta1 expression and the role of angiotensin-converting enzyme inhibitor on perianastomotic intimal hyperplasia in polytetrafluoroethylene graft implanted in rabbit carotid artery. | evel in perianastomotic graft tissue by reverse transcription-polymerase chain reaction (RT-PCR). The IMHRs gradually increased from 1 to 14 weeks in both groups (vs. 1 wk in each group; p<0.05). The IMHRs of the Graft plus ACEI group were comparable to those of Graft Alone group at 1 week; but significantly lower at 8 and 14 weeks (vs. Graft Alone group; p<0.05). The TGF-beta1 mRNA expression levels of the Graft plus ACEI group were clearly lower than those of the Graft Alone group at 1 and 8 weeks (vs. Gr | 15682830 | [
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Transforming growth factor-beta1 expression and the role of angiotensin-converting enzyme inhibitor on perianastomotic intimal hyperplasia in polytetrafluoroethylene graft implanted in rabbit carotid artery. | aft Alone group; p<0.05); but similar at 14 weeks. TGF-beta1 in the synthetic artery graft of the Graft Alone group was up-regulated as early as 1 week after the operation; when no definitive development of a quantifiable neointima was observed. The TGF-beta1 mRNA expression of the Graft Alone group was highest at 8 weeks and lowest at 14 weeks (vs. 1 week; *p<0.05); but such time-dependent changes were not observed in the Graft plus ACEI group. The results indicated that ACEI reduced intimal hyperplasia in | 15682830 | [
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Transforming growth factor-beta1 expression and the role of angiotensin-converting enzyme inhibitor on perianastomotic intimal hyperplasia in polytetrafluoroethylene graft implanted in rabbit carotid artery. | the grafts of the Graft plus ACEI group and also suppressed TGF-beta1 mRNA expression in perianastomotic intimal hyperplasia tissues to the normal artery level. Perianastomotic intimal hyperplasia in synthetic arterial graft is considered to be related to TGF-beta1; the expression of which is locally mediated by angiotensin II and; therefore; suppressed by ACEI. | 15682830 | [
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Suspension technique improves rapid recovery of urinary continence following radical retropubic prostatectomy. | We investigated whether a suspension technique of vesicourethral anastomosis with pubo-prostatic ligaments improved urinary continence following radical retropubic prostatectomy. The suspension of vesicourethral anastomosis was performed in 55 consecutive patients with clinically localized prostate cancer by placement of two stitches; which were anchored to pubo-prostatic ligaments preserving their anterior attachments to the pubic bone. Continence rates; positive rates of surgical margins; and complication | 15682831 | [
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Suspension technique improves rapid recovery of urinary continence following radical retropubic prostatectomy. | s in these patients after radical prostatectomy were compared with the results of 30 randomly selected patients in whom a suspension technique was not performed. There were no significant differences in the positive rates of either surgical margins or complications between these two groups. In contrast; continence rates in the suspension group at one and three months (75% and 89%) were significantly higher than those (13% [p<0.001] and 67% [p<0.01]) of the control group. The suspension technique appears to | 15682831 | [
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Suspension technique improves rapid recovery of urinary continence following radical retropubic prostatectomy. | have an advantage in immediate recovery of urinary continence following radical retropubic prostatectomy. | 15682831 | [
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Fiber type-specific localization of monocarboxylate transporters MCT1 and MCT4 in rat skeletal muscle. | For many years it was thought that lactic acid traverses plasma membranes by diffusion; however; it has been shown in recent years that lactic acid and other monocarboxylates are transported through these membranes together with H+ by monocarboxylate transporters (MCTs). Of these transporters; rat skeletal muscle has been found to contain MCT1 and MCT4. It is thought that MCT1 transports lactic acid into the skeletal muscle from outside the skeletal muscle cells; while MCT4 is involved in the extrusion of l | 15682832 | [
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Fiber type-specific localization of monocarboxylate transporters MCT1 and MCT4 in rat skeletal muscle. | actic acid out of the muscle cells. It has been reported that the concentration of MCT1 within the skeletal muscle is highest in muscle fibers with superior oxidative glycolytic capacity; whereas MCT4 concentrations are highest in fibers with greater anaerobic glycolytic capacity. However; the relation between MCT1 and MCT4 localization and muscle fiber type has not been clarified from a morphological viewpoint. The present study applied morphological methods to examine the relation between fiber type and l | 15682832 | [
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Fiber type-specific localization of monocarboxylate transporters MCT1 and MCT4 in rat skeletal muscle. | ocalization of MCT1 and MCT4 in Wistar rat skeletal muscle. After the animals were perfusion-fixed in 4% paraformaldehyde; the extensor digitorum longus muscle (EDL) and the soleus muscle (SOL) were dissected out and MCT1 and MCT4 localization were immunohistochemically determined in serial sections. In addition; adjacent sections were immunohistochemically stained with parvalbumin to identify muscle fiber types. Results showed clearly that MCT1 was present on the plasma membranes of all type I fibers; wher | 15682832 | [
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Fiber type-specific localization of monocarboxylate transporters MCT1 and MCT4 in rat skeletal muscle. | eas MCT4 was localized on the plasma membranes of all type IIb fibers. Both MCT1 and MCT4 were found on nearly all intermediate type IIa fibers. The authors consider that these relationships between muscle fiber type and MCT1 or MCT4 localization reflect the differences in glycolytic metabolism that have been reported between the different muscle fiber types. | 15682832 | [
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Caveolae localization and caveolin expressions in Schwann cells of mature rat spinal nerves. | Caveolae are a specific plasmalemmal microdomain which appear as flask-like invaginations and/or vesicles attaching just beneath the plasmalemma. Caveolae are present in many cell types and are found in the Schwann cells that ensheath myelinated and unmyelinated nerve fibers of the peripheral nervous tissues. However; the precise distribution in the Schwann cell plasmalemma and the functional properties of these caveolae remains obscure. The present study revealed: (1) Caveolae are most commonly observed in | 15682833 | [
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Caveolae localization and caveolin expressions in Schwann cells of mature rat spinal nerves. | the Schwann cell plasmalemma of myelinated nerve fibers. (2) Caveolae are principally located in the perikaryal plasmalemma of Schwann cells of the myelinated nerves. (3) Caveolin-1 is expressed strongly in Schwann cell caveolae. (4) Caveolin 2 and 3 are also immunohistochemically detected in Schwann cell caveolae; although the immunoreactivities are slight. The results suggested that caveolae of the peripheral nervous system are involved in cellular activities specific to Schwann cells in myelinated nerve | 15682833 | [
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Caveolae localization and caveolin expressions in Schwann cells of mature rat spinal nerves. | fibers. These caveolae may contain receptors for signaling molecules that could affect the myelinated nerve fibers; and/or proteins related to ion transfer activity. Further studies are necessary in order to clarify the types of proteins associated with Schwann cell caveolae. | 15682833 | [
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West syndrome associated with administration of a histamine H1 antagonist, oxatomide. | We report a 4-month-old female infant who developed West syndrome eleven days after administration of a histamine H1 antagonist; oxatomide; for atopic dermatitis. It has been reported that some histamine H1 antagonists induce seizures in epileptic patients. The age; the interval between oxatomide administration; and the onset of West syndrome and its clinical course were similar to two previously reported 3-month-old infants with West syndrome associated with ketotifen administration. We should be cautious | 15682834 | [
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West syndrome associated with administration of a histamine H1 antagonist, oxatomide. | in using the histamine H1 antagonists; oxatomide and ketotifen; in young infants because such agents could potentially disturb the anticonvulsive central histaminergic system. | 15682834 | [
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A long-term follow-up study of four cases who underwent curettage and autogenous bone grafting for steroid-related osteonecrosis of the femoral condyle. | We performed curettage followed by autogenous bone grafting in several cases of steroid-related osteonecrosis of the femoral condyle; and reviewed the outcome of this procedure after a mean follow-up of 9.5 years. The number of patients was 4; the mean age at the time of the operation was 30.5 years. The mean Knee Society Objective Score was 52.5 before the operation and had increased to 87.5 at the time of the review. The pre-operative radiographic stages were stage 2 in 2 patients and stage 3 in the other | 15682835 | [
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A long-term follow-up study of four cases who underwent curettage and autogenous bone grafting for steroid-related osteonecrosis of the femoral condyle. | 2 patients. Progression in the disease stage was observed in 3 patients. MRI revealed survival of the grafted bone in only one case; and collapse of the articular surface in all cases. In conclusion; though the clinical results showed improvement; the autogenous bone graft failed to answer the purpose of preventing the progression in disease stage. | 15682835 | [
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Anomalous origin of the right coronary artery: report of a case. | A 63-year-old man was admitted with a complaint of dyspnea. Echocardiography showed severe aortic regurgitation (AR); and moderate mitral regurgitation (MR). Coronary angiography revealed that the right coronary artery (RCA) arose from the ascending aorta with a high takeoff and a significant stenosis at the distal segment of the RCA. Scintigraphy with Thallium showed a transient perfusion defect on the inferior wall. The diagnosis of AR and MR associated with anomalous origin of the RCA and myocardial isch | 15682836 | [
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Anomalous origin of the right coronary artery: report of a case. | emia was made. After successful catheter intervention for stenosis of the RCA; an operation was performed on the aortic and mitral valve. At surgery; the orifice of the RCA was located above the commissure of the right and left coronary cusps and the shape was obliquely elliptical. The RCA originated at an acute angle from the ascending aorta; and its proximal segment was incorporated in the wall of the aorta. After aortic valve replacement and mitral valve repair; a neo-ostium without unroofing of the intr | 15682836 | [
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Anomalous origin of the right coronary artery: report of a case. | amural segment of the RCA was created at the proximal RCA; and the intima of the RCA was fixed to the intima of the aorta. The patient recovered uneventfully and is doing well without findings of myocardial ischemia at present 40 months after operation. | 15682836 | [
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Graciloplasty for internal and external sphincteric resection of lower rectal cancer. | Anal sphincteric resection for rectal cancer is most commonly followed by colostomy in the lower abdominal wall; which enforces quite a poor quality of life due to a permanent stoma. For surgeons treating lower rectal cancer; the goal is to achieve defecation via the anus without placing a stoma. Internal sphincteric resection; partial external sphincteric resection and coloanal anastomosis have been reported for the treatment of lower rectal cancer with avoiding a colostoma. Extended resection of the exter | 15682837 | [
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Graciloplasty for internal and external sphincteric resection of lower rectal cancer. | nal sphincter; however; limits patient's daily activities because of poor functional results and necessitates reconstruction of damaged anal function. This paper describes a case of graciloplasty for postoperative anal dysfunction that yielded a good clinical outcome in a 65-year-old female who had undergone very low anterior resection with complete internal and partial external sphincteric resection for lower rectal cancer. | 15682837 | [
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[Retinal pigment epithelial cells contribute to maturation and fenestration of the vascular endothelial cells in vascular endothelial growth factor-transgenic mice]. | To demonstrate the role of the retinal pigment epithelial cells (RPE) in subretinal neovascularization during maturation and fenestration of endothelial cells in vascular endothelial growth factor (VEGF) transgenic mice.VEGF transgenic mice were given an intraperitoneal injection of 50 mg/kg of sodium iodate (treated) or physiological saline (controls) on postnatal day 10. Fluorescein angiography (FAG) was carried out and the mice were sacrificed on postnatal day 31. The eyes were removed and processed for | 15682839 | [
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[Retinal pigment epithelial cells contribute to maturation and fenestration of the vascular endothelial cells in vascular endothelial growth factor-transgenic mice]. | light and electron microscopy.FAG showed leakage from neovascularization in both groups; but there were fewer leakages in the treated group than in the control group. Electron microscopy showed subretinal neovascularization in both groups; but there were fewer fenestrations and less maturity of endothelial cells in the new vessels of mice in the treated group. In the treated mice; damaged RPE cells did not completely enclose new vessels and the endothelial cells were immature.It is suggested that RPE cells | 15682839 | [
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[Retinal pigment epithelial cells contribute to maturation and fenestration of the vascular endothelial cells in vascular endothelial growth factor-transgenic mice]. | promote endothelial cell maturation and formation of fenestrations in VEGF-induced subretinal neovascularization. | 15682839 | [
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[Change in refraction and intraocular lens position after cataract surgery]. | To evaluate the differences between various intraocular lens (IOL)s in refractive change and anterior shift of the IOL after cataract surgery.Postoperative refractive change was analyzed 1 week to 12 months after cataract surgery using an autorefractmeter in 4 patient groups implanted with 811 C (HSM-PMMA; 83 eyes); 824 C (HSM-PMMA; 80 eyes); AQ 110 NV (3-piece silicone; 191 eyes); and MA 60 BM (3-piece acrylic; 80 eyes). Anterior-posterior shift of an IOL after surgery was studied using an anterior segment | 15682840 | [
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[Change in refraction and intraocular lens position after cataract surgery]. | analyzer (EAS-1000) in 2 groups (824 C and AQ 110 NV). Refractive change after YAG laser posterior capsulotomy was also evaluated in 2 groups (811 C RESULTS: Only the AQ 110 NV group demonstrated statistically significant myopic change; which gradually increased until 12 months after cataract surgery; and significant anterior shift of an IOL 3 months after surgery. Significant refractive change was not observed after YAG capsulotomy.A silicone IOL (AQ 110 NV); but not HSM-PMMA or acrylic IOL; shifted anter | 15682840 | [
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[Change in refraction and intraocular lens position after cataract surgery]. | iorly; resulting in myopic change after cataract surgery. | 15682840 | [
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[Difference of optic disc topography between a low-tension group and a high-tension group in normal-tension glaucoma patients]. | Glaucomatous visual field loss and optic disc damage differ by intraocular pressure (IOP) levels. In this study; we compared the optic disc topography in the high-tension group and the low-tension group in normal-tension glaucoma (NTG).We selected NTG patients with mean deviation (MD) > or = -10.00 dB and the highest recorded IOP of < 14 mmHg or > or = 17 mmHg without glaucoma treatment. We classified NTG eyes into the following two groups: 1) a low-tension group with the highest recorded IOP of < 14 mmHg; | 15682841 | [
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[Difference of optic disc topography between a low-tension group and a high-tension group in normal-tension glaucoma patients]. | 2) a high-tension group with the highest recorded IOP of > or = 17 mmHg. The optic disc parameters in the low-tension group eyes were compared with those in the high-tension group eyes using a Heidelberg Retina Tomograph.Nineteen eyes of nineteen patients were selected for each group. The cup/disc area ratio in the global sector; and the rim volume in the nasal sector of the low-tension group had deteriorated more than in the high-tension group.The disc topography is different between the low-tension group | 15682841 | [
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[Difference of optic disc topography between a low-tension group and a high-tension group in normal-tension glaucoma patients]. | and the high-tension group in the nasal sector; suggesting that different pathogenetic mechanisms exist in the optic disc damage in NTG. | 15682841 | [
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[Bilateral posterior ischemic optic neuropathy following subdural hematoma drainage]. | We report a case of bilateral posterior ischemic optic neuropathy after subdural hematoma drainage.A 52-yr-old man under continuous peritoneal dialysis underwent subdural hematoma drainage. After administration of a sedative; he complained of bilateral visual loss. His visual acuity was light perception in the right eye and no light perception in the left eye. Neither pupil reacted to light stimulus. Funduscopic findings revealed a slightly pale optic disc and renal retinopathy with macular folds in both ey | 15682842 | [
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[Bilateral posterior ischemic optic neuropathy following subdural hematoma drainage]. | es. No other neuro-ophthalmologic or neurologic abnormalities were observed. Based on these findings; the patient was diagnosed as having bilateral posterior ischemic optic neuropathy and was treated with intravenous corticosteroids. From about 50 days after the operation; visual acuity gradually improved; and papillary light reaction was immediate. In cranial magnetic resonance imaging; no characteristic lesions of multiple sclerosis could be detected. Six months later; visual acuity improved to 20/20 in b | 15682842 | [
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[Bilateral posterior ischemic optic neuropathy following subdural hematoma drainage]. | oth eyes.In patients with renal failure and underlying systemic vascular disease and anemia; the risk of posterior ischemic optic neuropathy should be considered even in minor surgery with stable vital signs and without severe blood loss. | 15682842 | [
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Diagnostic I-131 scintigraphy in patients with differentiated thyroid cancer: no additional value of higher scan dose. | After initial treatment with total thyroidectomy and radioiodine ablation; most follow-up protocols for patients with differentiated thyroid carcinoma contain cyclic diagnostic I-131 imaging and serum thyroglobulin measurements. The applied diagnostic I-131 doses vary between 37 and 370 MBq. The aim of this study was to determine the yield of a diagnostic scan with 370 MBq I-131 in patients with a negative diagnostic scan with 74 MBq I-131.Retrospective evaluation of 158 patients who received a high-dose di | 15682843 | [
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Diagnostic I-131 scintigraphy in patients with differentiated thyroid cancer: no additional value of higher scan dose. | agnostic scan with 370 MBq I-131 because of a negative low-dose diagnostic scan with 74 MBq I-131. Special attention was paid to the patients with positive high-dose diagnostic scanning and undetectable serum thyroglobulin levels after thyroid hormone withdrawal.In 127 (80%) of patients the 370 MBq I-131 scan was negative; just like the preceding low-dose scan. In 31 (20%) of patients abnormal uptake was present on the 370 MBq diagnostic scan. In 19 of these 31 patients serum thyroglobulin was undetectable. | 15682843 | [
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Diagnostic I-131 scintigraphy in patients with differentiated thyroid cancer: no additional value of higher scan dose. | In 15/19 the high-dose diagnostic scan proved either false positive or demonstrated clinically irrelevant minor ablation rests. In only four patients (2.5%) did the high-dose diagnostic scans reveal possibly relevant uptake caused by residual differentiated thyroid cancer.In 98% of patients a 370 MBq dose of I-131 for diagnostic WBS had no additional value. The combination of a low-dose diagnostic I-131 scan using only 74 MBq combined with a serum Tg level measurement proved sufficient for correct clinical | 15682843 | [
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Diagnostic I-131 scintigraphy in patients with differentiated thyroid cancer: no additional value of higher scan dose. | decision making regarding whether the patient requires additional I-131 therapy. | 15682843 | [
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Scatter and cross-talk correction for one-day acquisition of 123I-BMIPP and 99mtc-tetrofosmin myocardial SPECT. | 123I-15-(p-iodophenyl)-3-(R;S)-methylpentadecanoic acid (BMIPP) and 99mTc-tetrofosmin (TET) are widely used for evaluation of myocardial fatty acid metabolism and perfusion; respectively. ECG-gated TET SPECT is also used for evaluation of myocardial wall motion. These tests are often performed on the same day to minimize both the time required and inconvenience to patients and medical staff. However; as 123I and 99mTc have similar emission energies (159 keV and 140 keV; respectively); it is necessary to con | 15682844 | [
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Scatter and cross-talk correction for one-day acquisition of 123I-BMIPP and 99mtc-tetrofosmin myocardial SPECT. | sider not only scattered photons; but also primary photons of each radionuclide detected in the wrong window (cross-talk). In this study; we developed and evaluated the effectiveness of a new scatter and cross-talk correction imaging protocol.Fourteen patients with ischemic heart disease or heart failure (8 men and 6 women with a mean age of 69.4 yr; ranging from 45 to 94 yr) were enrolled in this study. In the routine one-day acquisition protocol; BMIPP SPECT was performed in the morning; with TET SPECT pe | 15682844 | [
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Scatter and cross-talk correction for one-day acquisition of 123I-BMIPP and 99mtc-tetrofosmin myocardial SPECT. | rformed 4 h later. An additional SPECT was performed just before injection of TET with the energy window for 99mTc. These data correspond to the scatter and cross-talk factor of the next TET SPECT. The correction was performed by subtraction of the scatter and cross-talk factor from TET SPECT. Data are presented as means +/- S.E. Statistical analyses were performed using Wilcoxon's matched-pairs signed-ranks test; and p < 0.05 was considered significant.The percentage of scatter and cross-talk relative to t | 15682844 | [
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Scatter and cross-talk correction for one-day acquisition of 123I-BMIPP and 99mtc-tetrofosmin myocardial SPECT. | he corrected total count was 26.0 +/- 5.3%. EDV and ESV after correction were significantly greater than those before correction (p = 0.019 and 0.016; respectively). After correction; EF was smaller than that before correction; but the difference was not significant. Perfusion scores (17 segments per heart) were significantly lower after as compared with those before correction (p < 0.001).Scatter and cross-talk correction revealed significant differences in EDV; ESV; and perfusion scores. These observation | 15682844 | [
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Scatter and cross-talk correction for one-day acquisition of 123I-BMIPP and 99mtc-tetrofosmin myocardial SPECT. | s indicate that scatter and cross-talk correction is required for one-day acquisition of 123I-BMIPP and 99mTc-tetrofosmin SPECT. | 15682844 | [
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Quantitative three-phase bone scintigraphy in the evaluation of intravenous regional blockade treatment in patients with stage-I reflex sympathetic dystrophy of upper extremity. | To investigate the role of quantitative three phase bone scintigraphy (QTPBS) in the evaluation of efficacy of intravenous regional blockade treatment in patients having reflex sympathetic dystrophy (RSD) of the upper extremity.Twenty-six patients with stage-I RSD were focused on in this study. Patients were treated with physical therapy and intravenous (I.V.) regional blockade therapy consisting of dexamethasone and lidocaine. All patients were clinically evaluated before and 1 month after the completion o | 15682845 | [
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Quantitative three-phase bone scintigraphy in the evaluation of intravenous regional blockade treatment in patients with stage-I reflex sympathetic dystrophy of upper extremity. | f the therapy protocol. QTPBS was applied to patients before therapy and 1 month after the therapy. As a control group; 11 healthy subjects also underwent QTPBS. Perfusion; hyperemic and fixation indices were calculated from three-phase bone scintigraphy.All patients showed statistically significant clinical improvement after the therapy (p < 0.01). Pre-treatment; perfusion (1.67 +/- 0.63); hyperemic (1.44 +/- 0.48) and fixation (1.69 +/- 0.48) indices of patients were higher than those of healthy subjects | 15682845 | [
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Quantitative three-phase bone scintigraphy in the evaluation of intravenous regional blockade treatment in patients with stage-I reflex sympathetic dystrophy of upper extremity. | (PI: 0.95 +/- 0.05; HI: 0.94 +/- 0.06; FI: 1.01 +/- 0.2) (p < 0.01) and all indices significantly decreased after the treatment (PI: 1.33 +/- 0.46; HI: 1.18 +/- 0.23; FI: 1.42 +/- 0.26) (p < 0.01).I.V. regional blockade therapy combined with corticosteroids is a simple; safe and effective method for the treatment of patients with stage-I RSD in the upper extremity. QTPBS is a valuable and objective method to evaluate the response to therapy and may be useful for staging of patients and predicting the respon | 15682845 | [
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Quantitative three-phase bone scintigraphy in the evaluation of intravenous regional blockade treatment in patients with stage-I reflex sympathetic dystrophy of upper extremity. | se to therapy. | 15682845 | [
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Accuracy and reproducibility of co-registration techniques based on mutual information and normalized mutual information for MRI and SPECT brain images. | We implemented a 3D co-registration technique based on mutual information (MI) including 2D image matching as a coarse pre-registration. The 2D coarse pre-registration was performed in the transverse; sagittal and coronal planes sequentially; and all six parameters were then optimized as fine registration. Normalized mutual information (NMI) was also examined as another entropy-based measure that was invariant to the overlapped area of two images. In order to compare accuracy and precision of the present me | 15682846 | [
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Accuracy and reproducibility of co-registration techniques based on mutual information and normalized mutual information for MRI and SPECT brain images. | thod with a conventional two-level multiresolution approach; simulation was performed by 100 trials with the random initial mismatch of +/-10 degrees and +/-17.92 mm (Type-I) and +/-20 degrees and +/-40.32 mm (Type-II). For Type-I; no significant differences were found between registration errors of the multiresolution approach and the present method with the MI criterion. No biases were observed (< or =0.13 degrees and < or =0.57 mm for the multiresolution approach; < or =0.12 degrees and < or =0.57 mm for | 15682846 | [
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Accuracy and reproducibility of co-registration techniques based on mutual information and normalized mutual information for MRI and SPECT brain images. | the present method) and the SDs were very small (< or =0.18 degrees and < or =0.12 mm for the multiresolution approach; < or =0.11 degrees and < or =0.11 mm for the present method). For Type-II; SDs for the multiresolution approach (< or =1.8 degrees and < or =0.88 mm) were markedly larger than those for the present method (< or =0.64 degrees and < or =0.20 mm) with MI. Success rate for the present method was 99.9%; which was higher than 97.6% for the multiresolution approach. Simulation also revealed that | 15682846 | [
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Accuracy and reproducibility of co-registration techniques based on mutual information and normalized mutual information for MRI and SPECT brain images. | MI and NMI performance were almost equivalent. The choice of optimization strategy more affected accuracy and reproducibility than the choice of the registration criterion (MI or NMI) in our simulation condition. The present method is sufficiently accurate and reproducible for MRI-SPECT registration in clinical use. | 15682846 | [
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18F-FDG and 11C-methionine PET for evaluation of treatment response of lung cancer after stereotactic radiotherapy. | This study was performed to investigate the feasibility of FDG- and L-[methyl-11C]methionine (Met)-PET for the follow up of lung cancer after stereotactic radiotherapy (SRT). Nine patients (pt) with solitary lung cancer underwent SRT. Met- and FDG-PET studies were performed one week before SRT and from one week to 8 months after SRT. Responses to SRT were complete in 2 pt and partial in 7 pt. Met- and FDG-PET scan showed high tracer uptake in all tumors before SRT. After SRT; standardized uptake values (SUV | 15682847 | [
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18F-FDG and 11C-methionine PET for evaluation of treatment response of lung cancer after stereotactic radiotherapy. | ) of FDG and Met changed concordantly. Both decreased with time in 5 pt but did not decrease steadily in 4 pt; where 2 pt showed an increase at 1 to 2 weeks after SRT and 2 pt showed an increase at more than 3 months after SRT. The former appears to reflect the acute reaction to SRT and the latter radiation-induced pneumonitis. Although the addition of Met-PET did not provide additional information over FDG-PET; FDG- and Met-PET could be used to evaluate the treatment effect of SRT. | 15682847 | [
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] |
Pattern of 111In-chloride bone marrow scintigraphy in myelodysplastic syndrome; comparison with clinical characteristics. | 111In-chloride bone marrow scintigraphy (bone marrow scintigraphy) was performed in patients with myelodysplastic syndrome (MDS); tracer accumulation was classified into patterns; and the relationship between the accumulation patterns and prognostic factors was investigated to assess the usefulness of bone marrow scintigraphy. The subjects were 14 patients diagnosed with MDS. Accumulation of the bone marrow scintigraphy tracer was classified according to the degree of accumulation in the axial bone marrow a | 15682848 | [
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Pattern of 111In-chloride bone marrow scintigraphy in myelodysplastic syndrome; comparison with clinical characteristics. | nd peripheral expansion. International Prognostic Scoring System (IPSS); which are frequently used for prognostic evaluation of MDS; and conversion to leukemia were investigated in prognostic factors. We also investigated the relationship between enlargement of the liver and spleen and the prognostic factors. The accumulation patterns were as follows: pattern I; The normal accumulation pattern (2 cases); pattern II; the expanded accumulation pattern (6 cases); pattern III; low accumulation pattern (5 cases) | 15682848 | [
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Pattern of 111In-chloride bone marrow scintigraphy in myelodysplastic syndrome; comparison with clinical characteristics. | ; and pattern IV; heterogeneous accumulation pattern (1 case). The relationships between the two prognostic factors and accumulation patterns were investigated; and the prognosis was found to be significantly poorer in the patients with the low accumulation pattern than the expanded accumulation pattern. Enlargement of the liver and spleen was not significantly correlated with the prognostic factors. | 15682848 | [
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Evaluation of dilated upper renal tracts by technetium-99m ethylenedicysteine F+O diuresis renography in infants and children. | To evaluate the feasibility of modifying diuresis renography by the simultaneous administration of Tc-99m ethylenedicysteine and furosemide in the investigation of hydronephrosis and hydroureteronephrosis in infants and children. Parameters assessed were the diuretic response in normal kidneys and the ability of the F+0 study to differentiate between renal obstruction and nonobstruction.One hundred and thirty-three children (93 males; 40 females; mean age 35.2 months) with sonographic diagnoses of hydroneph | 15682849 | [
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Evaluation of dilated upper renal tracts by technetium-99m ethylenedicysteine F+O diuresis renography in infants and children. | rosis or hydroureteronephrosis underwent F+0 diuresis renography. Tc-99m ethylenedicysteine (3.7 MBq/kg body weight) and furosemide at an appropriate dose were administered intravenously at the start of the study. Posterior imaging of the kidneys and bladder was performed for 20 min followed by imaging after voiding. All patients were followed-up for 12 months; and the results of the initial F+0 diuresis renography were compared with the final diagnoses. Final diagnosis was based on the pediatric urologist' | 15682849 | [
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Evaluation of dilated upper renal tracts by technetium-99m ethylenedicysteine F+O diuresis renography in infants and children. | s decision of either surgery or conservative management.A renal unit was defined as a kidney and its ureter. There were 262 renal units with 4 patients having a solitary kidney. 90 normal and 172 abnormal renal units on sonography were assessed by F+0 diuresis renography. The furosemide clearance half time for the 90 normal renal units was 5.8 +/- 1.4 min. Of the 172 abnormal renal units; 100 were classified as nonobstructed and 72 as obstructed on diuresis renography. All 100 nonobstructed renal units were | 15682849 | [
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Evaluation of dilated upper renal tracts by technetium-99m ethylenedicysteine F+O diuresis renography in infants and children. | correctly classified with no false-negative studies; of the 72 renal units classified as obstructed; there were 43 true-positive studies and 29 false-positive studies. The sensitivity was 100%; specificity was 78% and accuracy was 83%.Tc-99m ethylenedicysteine F+0 diuresis renography is a valid method for the investigation of hydronephrosis and hydroureteronephrosis in infants and children. | 15682849 | [
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A large renal pelvic diverticulum, presenting incomplete excretion during tc-99m MAG-3 scintigraphy and tracer accumulation on tc-99m DMSA scintigraphy; a case report. | This case report illustrates the dynamic and static renal scintigraphic images of a patient with an unusual large diverticulum of the renal pelvis. The initial diagnosis by intravenous pyelography (IVP) and ultrasonographic (US) examination was a renal pelvic diverticulum of the left kidney; and the patient was referred to the nuclear medicine department for exploration of the effect of the pelvic diverticulum on renal functions. We performed dynamic renal scintigraphy with technetium-99m (Tc-99m) labeled m | 15682850 | [
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A large renal pelvic diverticulum, presenting incomplete excretion during tc-99m MAG-3 scintigraphy and tracer accumulation on tc-99m DMSA scintigraphy; a case report. | ercaptoacetyl triglycine (MAG-3) and static renal scintigraphy with Tc-99m labeled dimercaptosuccinic acid (DMSA). In dynamic renal scintigraphy; bilaterally normal concentration function was observed. While right kidney excretion function was normal; an incomplete excretion pattern was seen on the left side. Complete urinary flow obstruction occurred approximately at the 10th minute of the acquisition; which did not seem to respond to the i.v. furosemide application. However; when only the renal cortex was | 15682850 | [
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A large renal pelvic diverticulum, presenting incomplete excretion during tc-99m MAG-3 scintigraphy and tracer accumulation on tc-99m DMSA scintigraphy; a case report. | included in the region of interest; the obstructive pattern disappeared. In static renal scintigraphy; a large renal pelvic diverticulum localized antero-medially was clearly visualized in the left-anterior oblique projection; most probably due to accumulation of radiopharmaceutical inside it. This case showed that a renal pelvic diverticulum should be thought of when an incomplete excretion pattern is seen on dynamic renal scintigraphy. Using only a cortical region of interest may also help to distinguish | 15682850 | [
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A large renal pelvic diverticulum, presenting incomplete excretion during tc-99m MAG-3 scintigraphy and tracer accumulation on tc-99m DMSA scintigraphy; a case report. | other types of obstructive pattern from diverticulum. Additionally; Tc-99m DMSA scintigraphy may show diverticulum localization with antero-oblique projections in addition to routine projections. | 15682850 | [
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Absence of pulmonary uptake of Tc-99m methylenediphosphonate in alveolar microlithiasis. | Pulmonary alveolar microlithiasis (PAM) is a rare disease of unknown etiology characterized by accumulation of calcific concretions in the alveolar spaces. The paper reports a case of PAM in a 56-year-old male. The patient had persistent dry cough; and gradually progressive dyspnea on exertion. The diagnosis was established on the basis of roentgenography and confirmed by the sputum and transbronchial biopsy findings. Scintigraphy revealed the absence of Tc-99m methylenediphosphonate uptake of lungs. Famili | 15682851 | [
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Absence of pulmonary uptake of Tc-99m methylenediphosphonate in alveolar microlithiasis. | al occurrence was not observed. Chest roentgenogram; pulmonary function; and clinical status of the patient have remained stable for 41 months. Radiological and clinical follow-up of the disease continues. | 15682851 | [
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A case of small cell carcinoma of the esophagus detected incidentally by FDG-PET. | Small cell carcinoma (SmC) of the esophagus is rare; and is sometimes impossible to detect by macroscopic inspection using an endoscope or histological examination of biopsied specimens. A 73-year-old man received F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) to evaluate the response to radiofrequency thermal ablation therapy for lung cancer. FDG-PET showed abnormal accumulation in the posterior mediastinum. Endoscopy disclosed ulcerous lesions with marginal elevation in the middle segment | 15682852 | [
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A case of small cell carcinoma of the esophagus detected incidentally by FDG-PET. | of the esophagus; but the biopsy specimen taken concurrently was not malignant histologically. FDG-PET; performed two months later; revealed abnormal accumulation in the suspect area; and the extent of accumulation was wider than previously. Histological examination of the specimen biopsied during the endoscopy led to a diagnosis of SmC. FDG-PET thus proved useful in the early detection of SmC. | 15682852 | [
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Diffuse splenic Tc-99m MDP uptake in hypersplenic patient. | A 52-year-old woman with nonspecific left leg pain was examined by Tc-99m methylene diphosphonate (MDP) bone scintigraphy. The patient had been a marble quarry worker for 10 years and had developed chronic congestive heart failure secondary to pneumoconiosis. Her hemoglobin analysis and hematologic findings were interpreted as being consistent with sickle cell beta+ thalassemia and also hypersplenism. Bone scintigraphy showed intense and diffuse MDP accumulation in the enlarged spleen without ultrasonograph | 15682853 | [
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Diffuse splenic Tc-99m MDP uptake in hypersplenic patient. | ic or radiologic evidence of calcification. | 15682853 | [
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Improved detection of axillary hot nodes in lymphoscintigraphy in breast cancer located in the upper lateral quadrant with additional projection imaging. | Sentinel node (SN) biopsy has been becoming a standard method for early stage breast cancer. Scintigraphic image of SN helps the biopsy procedure. It is reported that the scintigraphic detection rate is not 100%. The value of taking additional projection view in SN detection was assessed in breast cancer patients.Consecutive 114 breast cancer patients with upper lateral quadrant tumor were included in this study. After injection of 99mTc-phytate; scintigram was taken at the projection of anterior oblique (A | 15682854 | [
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Improved detection of axillary hot nodes in lymphoscintigraphy in breast cancer located in the upper lateral quadrant with additional projection imaging. | O) 30 degrees view and an additional AO 60 degrees view. Images were evaluated visually.In 7 of 114 patients; an axillary hot node was hidden on the activity at the injected site on AO 30 degrees view; and was visualized on AO 60 degrees view. In 17 of 114 patients; the axillary hot node was seen as a hump from the injected activity; and was separate on AO 60 degrees view. In 90 of 114 patients; the axillary hot node was separately seen on AO 30 degrees view.Multi-directional views are helpful to depict the | 15682854 | [
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Improved detection of axillary hot nodes in lymphoscintigraphy in breast cancer located in the upper lateral quadrant with additional projection imaging. | axillary sentinel nodes that are concealed behind the injected radioactivity. | 15682854 | [
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[PSA change and morbidity of prostate cancer after dietary intervention of low-fat and high-soybean-protein diet for patients with high serum PSA level]. | A total of 164 patients with a high serum prostate specific antigen (PSA) level were enrolled in a supervised program of dietary intervention with a low-fat and high-soybean-protein diet. The primary endpoints were the evaluation of PSA change and morbidity of prostate cancer in this population. In the evaluable cases; the average serum PSA level had decreased 0.5 ng/ml after 3 months; 0.3 ng/ml after 6 months; and increased 0.1 ng/ml after 1 year. The change after 3 months was statistically significant (p= | 15682855 | [
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[PSA change and morbidity of prostate cancer after dietary intervention of low-fat and high-soybean-protein diet for patients with high serum PSA level]. | 0.018; paired t-test). The average PSA doubling time was 444 months. During this study period; 9 of the patients developed prostate cancer. These findings indicate that this dietary intervention method was temporarily able to decrease serum PSA level; and indicates the possibility of prevention of prostate cancer by dietary intervention. However; more detailed analysis is necessary to determine why PSA did not keep decreasing. | 15682855 | [
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