ENTITY
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DEFINITION
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C0033308
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
Progesterone-containing product|Progesterona|Progesteronum|Corpus Luteum Hormone|Therapeutic Progesterone|progesterones|Delta4-pregnene-3,20-dione|17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione|PROGESTERONE|PRG - Progesterone|Lutogynon|delta4-pregnene-3,20-dione|Gelbkörperhormon|delta(4)-Pregnene-3,20-dione|Pregnenedione|Pregnendione preparation|Product containing progesterone (medicinal product)|17alpha-Progesterone|luteal hormone|Progesteron|PRG|Progesterone (substance)|progesterone|(S)-Progesterone|Progestérone|Progesterone|(S)-4-Pregnene-3,20-dione|Progesterone preparation|17α-progesterone|(S)-Pregn-4-en-3,20-dione|Pregn-4-ene-3,20-dione|Corpus luteum hormone|therapeutic progesterone
progesterone
C0450231
null
Exogenous hormones (substance)
Exogenous hormones
C0068980
The orally bioavailable acetate salt of norethindrone, a synthetic progestin with some anabolic, estrogenic, and androgenic activities. As do all progestins, norethindrone binds to and activates nuclear progesterone receptors (PRs) in target tissues such as the pituitary and reproductive system; ligand-receptor complexes are translocated to the nucleus where they bind to progesterone response elements (PREs) located on target genes, followed by various transcriptional events and histone acetylation. Physiological effects include the inhibition of luteinizing hormone (LH) release, an increase in the endometrial luteal-phase, and alterations in endocervical mucus secretion.
Norethisterone Acetate|Norethisterone acetate|norethindrone acetate|acetate norethisterone|norethisterone acetate|Norethindrone acetate preparation|Norethisterone acetate (substance)|Norethisterone acetate preparation|Norethindrone Acetate|Estr-4-en-3-one, 17-(acetyloxy)-17-ethynyl-, (17beta)-|NORETHINDRONE ACETATE|Norethindrone acetate
norethindrone acetate
C0701303
null
RU 38486|RU-486|RU38486|R38486|RU486|486 ru|ru-486|ru486|ru 486|RU 486|R 38486|RU-38486
R-38486
C0069492
null
11 beta-(4-dimethylaminophenyl)-17 alpha-hydroxy-17 beta-(3-hydroxypropyl)-13 alpha-methyl-4,9-gonadien-3-one|Onapristone|Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxypropyl)-, (11beta,13alpha,17alpha)-
onapristone
C0626053
null
null
sural
C0023726
An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
Lincomycin-containing product|Product containing lincomycin (medicinal product)|Lincomycin (substance)|Lincolnensin|LINCOMYCIN|LCM|Lincomycin|Lincomycine|D-erythro-alpha-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-|Lincomicina|Cillimycin|Lincomycinum|lincomycin|Lincomycin A
lincomycin
C0430022
A specific test or series of steps done to help diagnose a disease or condition. Mammograms and colonscopies are examples of diagnostic procedures.
Diagnostic procedures|Diagnostic procedure (procedure)|diagnostic procedure|diagnostic procedures|Diagnostic Test|Diagnostic Technique|Diagnostic procedure, NOS|Diagnostic Method|diagnostic technique|Diagnostic Procedure|Diagnostic procedure
diagnostic procedure
C0065684
null
mannose receptor|mannose receptors|receptor, mannose
mannose receptor
C0333641
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
Atrophy (morphologic abnormality)|atrophies|atrophied|atrophic|Atrophic|Atrophy, NOS|atrophying|atrophy|Atrophy|ATROPHY|Atrophies|ATROPHIES
Atrophic
C0043046
A condition of involuntary weight loss of greater then 10% of baseline body weight. It is characterized by atrophy of muscles and depletion of lean body mass. Wasting is a sign of MALNUTRITION as a result of inadequate dietary intake, malabsorption, or hypermetabolism.
Wasting Syndrome|wasting diseases|wasting syndrome|Wasting Disease|wasting disease|Wasting disease, NOS|Wasting syndrome|Malnutrition/starvation/cachexia|Wasting Diseases|Wasting Syndromes|Wasting disease (disorder)|Wasting disease|WASTING GENERALIZED
Wasting Syndrome
C0026846
Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.
Muscle atrophy, NOS|ATROPHY MUSCLE|amyotrophia|Muscle wasting, NOS|Muscle Atrophy|Muscle wasting disorder|Muscular atrophy|Muscle atrophy|Atrophies, Muscle|Muscle Wasting|Muscle Atrophies|Atrophies, Muscular|muscular atrophy|Muscle thinning|muscular atrophies|Amyotrophia|amyotrophy|Amyotrophy, NOS|Muscle atrophy (disorder)|Atrophy, Muscular|Amyotrophy|amyotrophies|Amyotrophia, NOS|MUSCLE ATROPHY|muscle wasting|Amyotrophia NOS|Muscle wasting|muscle atrophy|Muscular atrophy, NOS|Muscular Atrophy|Atrophy, Muscle|Muscular Atrophies
Muscular Atrophy
C0662660
null
MACHA-FPhOC
3-((N-((N'-methylamino)carbonyl)-N-hydroxyamino)methyl)-6-(4'-fluorophenoxy)chromene
C0662660
null
MACHA-FPhOC
3-((N-((N'-methylamino)carbonyl)-N-hydroxyamino)methyl)-6-(4'-fluorophenoxy)chromene
C0003313
The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.
IMMUNE COMPLEXES|Antigen-Antibody Complex|Antigen Antibody Complex|immune complexes|Complexes, Antigen-Antibody|Antigen Antibody Complexes|Circulating immune complex|Immune complex, NOS|Immune Complexes|Antigen-Antibody Complexes|complex immune|CIC - Circulating immune complex|complexes immune|antigen antibody complex|Immune complex|Complexes, Immune|Immune complex (substance)|immune complexe|IC - Immune complex|antigen-antibody complex|immune complex|Complex, Immune|Complex, Antigen-Antibody|circulating immune complex|Immune Complex|antigen antibody complexes|Immune complexes
Immune complex
C0003313
The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.
IMMUNE COMPLEXES|Antigen-Antibody Complex|Antigen Antibody Complex|immune complexes|Complexes, Antigen-Antibody|Antigen Antibody Complexes|Circulating immune complex|Immune complex, NOS|Immune Complexes|Antigen-Antibody Complexes|complex immune|CIC - Circulating immune complex|complexes immune|antigen antibody complex|Immune complex|Complexes, Immune|Immune complex (substance)|immune complexe|IC - Immune complex|antigen-antibody complex|immune complex|Complex, Immune|Complex, Antigen-Antibody|circulating immune complex|Immune Complex|antigen antibody complexes|Immune complexes
Immune complex
C0003313
The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.
IMMUNE COMPLEXES|Antigen-Antibody Complex|Antigen Antibody Complex|immune complexes|Complexes, Antigen-Antibody|Antigen Antibody Complexes|Circulating immune complex|Immune complex, NOS|Immune Complexes|Antigen-Antibody Complexes|complex immune|CIC - Circulating immune complex|complexes immune|antigen antibody complex|Immune complex|Complexes, Immune|Immune complex (substance)|immune complexe|IC - Immune complex|antigen-antibody complex|immune complex|Complex, Immune|Complex, Antigen-Antibody|circulating immune complex|Immune Complex|antigen antibody complexes|Immune complexes
Immune complex
C1279040
null
Entire triceps brachii (body structure)|Entire triceps brachii|Entire triceps brachii muscle
Entire triceps brachii
C0424657
null
Weight steady (finding)|Weight static|Weight stable
Weight steady
C0238703
Individuals who have developed skills, physical stamina and strength or participants in SPORTS or other physical activities.
Athlete|athlete|Athletes|athletes|ATHLETE
Athletes
C0678121
A patient's energy expenditure at rest.
Metabolic Rate, Basal|Basal Metabolic Rate|Basal metabolic rate|basal metabolic rate|Rate, Basal Metabolic|Basal metabolism|BMR - Basal metabolic rate|basal metabolism|Basal metabolic rate (observable entity)|BMR|metabolism basal|Basal Metabolic Rates|Basal metabolism rate
Basal metabolic rate
C0597513
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. [GOC:go_curators]
steroidogenesis|steroid biosynthetic process|steroid formation|steroid biosynthesis|steroid anabolism|steroid synthesis
Steroid biosynthesis
C0619285
null
p-dioxin
1,4-dioxin
C0039601
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Testosteronum|Testosterone (substance)|4-androsten-17β-ol-3-one|Trans-Testosterone|Testosteron|Testosterona|Testosterone|(17Beta)-17-hydroxyandrost-4-en-3-one|Androst-4-en-17beta-ol-3-one|testosterones|Delta4-androsten-17beta-ol-3-one|17-beta-Hydroxy-4-Androsten-3-one|testosterone|Testosterone-containing product|17 beta Hydroxy 4 Androsten 3 one|17beta-hydroxy-4-androsten-3-one|TESTOSTERONE|Product containing testosterone (medicinal product)|Testostérone
testosterone
C0069115
Immunologically detectable substances found in the CELL NUCLEUS.
Nuclear Antigens|nuclear antigen|nuclear antigens
Antigens, Nuclear
C0000966
A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
Acetylaldehyde|ACETALDEHYDE|acetaldehyde|Acetaldehyde (substance)|Acetaldehyde|Acetic Aldehyde|Ethyl Aldehyde|ethanal|Ethanal|acetic aldehyde
acetaldehyde
C0054290
null
Tris-C(4)(5)|Thiazolium, 2,2'-(3-((3-butyl-4-methyl-2(3H)-thiazolylidene)ethylidene)-1-propene-1,3-diyl)bis(3-butyl-4-methyl-, diiodide)|2,2'-3-(2-(3-butyl-4-methyl-2-thiazolin-2-ylidene)ethylidene)propylene)bis(3-butyl-4-methyl thiazolinium iodide
butyl-platonin
C0054290
null
Tris-C(4)(5)|Thiazolium, 2,2'-(3-((3-butyl-4-methyl-2(3H)-thiazolylidene)ethylidene)-1-propene-1,3-diyl)bis(3-butyl-4-methyl-, diiodide)|2,2'-3-(2-(3-butyl-4-methyl-2-thiazolin-2-ylidene)ethylidene)propylene)bis(3-butyl-4-methyl thiazolinium iodide
butyl-platonin
C0428011
null
sperm morphology|Sperm morphology|Sperm morphology (observable entity)|morphology sperm
Sperm morphology
C0971174
Inhibin B, consisting of an alpha subunit and a beta B subunit linked by disulphide bonds, is a heterodimer hormone produced by the follicle cells of the ovary and by the Sertoli and Ledig cells of testis. Although other forms of inhibin also exist in men, inhibin B is the predominant form in the circulation in men.
Inhibin Beta|inhibin b|Inhibin B|inhibin B|Inhibin B (substance)
inhibin B
C0078794
A compound given in the treatment of conditions associated with zinc deficiency such as acrodermatitis enteropathica. Externally, zinc sulfate is used as an astringent in lotions and eye drops. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
Zinc sulfate|ZINC (AS SULFATE)|sulfate zinc|zinc sulfate|Sulfate, Zinc|Zinc Sulfate|Zinc sulfate-containing product|Zinc sulphate|Sulfuric acid, Zinc salt (1:1)|Zinc sulfate, unspecified|zinc sulphate|Product containing zinc sulfate (medicinal product)|ZINC SULFATE|ZINC SULFATE, UNSPECIFIED FORM|Zinc sulfate (substance)|Zinc sulfate, unspecified form|Zinc Sulfate, Unspecified Form|Zinc sulfate, unspecified hydrate
zinc sulfate
C0016410
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
Vitamin B c|Pteroyl-L-glutamic acid|Folic acid|ácido fólico|2-[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid|Pteroyl-L-monoglutamic acid|N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid|Acide folique|Pteroyl-L-glutamate|Acidum folicum|Pteroylmonoglutamic Acid|FA|FOLIC ACID|PteGlu|N-pteroyl-L-glutamic acid|vitamin M|Folic acid (substance)|L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-|Lactobacillus casei factor|Vitamin B<sub>c</sub>|Folic Acid|Pteroylglutamic acid preparation|Pteroylmonoglutamic acid|folicin|vitamin m|Folic acid-containing product|PGA|Product containing folic acid (medicinal product)|Folsäure|Vitamin B>c<|b c vitamin|pteroylmonoglutamic acid|Folic acid preparation|FA - Folic acid|folic acid|Vitamin Bc|pteroylglutamic acid|vitamin B complex|Pteroylglutamic Acid|Vitamin M|vitamin Bc|Vitamin B9|N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid|m vitamins|B9, Vitamin|N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid|Pteroylglutamic acid
folic acid
C0178638
A cofactor for 1-carbon transfer involved with DNA synthesis.
folate|folates|Vitamin B-11|Folate
folate
C0026022
Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.
Fluorescence Light Microscopy|FLUORESCENT MICROSCOPY|Fluorescence Microscopies|Fluorescence microscopy technique|Fluorescence microscopy|Fluorescence Microscopy|Microscopy, Light, Fluorescence|fluorescence microscopy|Microscopies, Fluorescence|Fluorescence microscopy technique (qualifier value)
Microscopy, Fluorescence
C1167331
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. [GOC:go_curators]
membrane outer|outer membrane
outer membrane
C0001216
The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.
Acrosomal vesicle (cell structure)|Acrosomal granule (cell structure)|Lysosome of male germ cell|acrosomal granule|Acrosome|Acrosomes|Lysosome of male germ cell (cell structure)|Acrosomal vesicle|acrosome|Acrosomal granule|Acrosomal cap|acrosomal vesicle
Acrosome
C0033603
A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
Product containing protamine (medicinal product)|Protamine (substance)|protamine|Protamine-containing product|Protamine|Protamina|PROTAMINE|Protamines
protamines
C0297439
A liver X receptor that is expressed primarily by cells in the liver and other metabolically-active tissues.
Nuclear Orphan Receptor LXR Alpha|Liver X Receptor-Alpha|Liver X Receptor Alpha|Nuclear Orphan Receptor LXR-Alpha|LXRalpha Protein|Oxysterols Receptor LXR Alpha|NR1H3 Protein|Oxysterols Receptor LXR-Alpha|LXR-Alpha Protein|Nuclear Receptor Subfamily 1, Group H, Member 3|LXR Alpha Protein|LXR-Alpha, Oxysterols Receptor
nuclear receptor subfamily 1, group H, member 3
C0369610
null
total lipid|total lipids
Total lipids
C0025017
The edible portions of any animal used for food including domestic mammals (the major ones being cattle, swine, and sheep) along with poultry, fish, shellfish, and game.
Meats|Meat (substance)|Meat|meats|meat
Meat
C0175925
null
dairy cattle|Dairy cattle|Cattle, dairy|cattle dairy|Cattle for milk production (organism)
Cattle for milk production
C0037047
Persons or animals having at least one parent in common. (American College Dictionary, 3d ed)
Sibling, NOS|SIBLING|Sibling (person)|Sib|sibling|Sibling|Siblings
Sibling
C0012737
The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.
Dissection, NOS|Tissue Dissection|Dissection - action (qualifier value)|dissections|Dissection|Dissection - action|Dissections|Dissection procedure|Dissection procedure (procedure)|dissection procedures|dissection
Tissue Dissection
C0006159
The production of offspring by selective mating or HYBRIDIZATION, GENETIC in animals or plants.
Breeding|Breedings|breeding|breed|breeds
Breeding
C0085187
A terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability. Its length is believed to be a few hundred base pairs.
Telomere|telomeres|Telomeres|telomere
telomere
C0021925
Introduction of a tube into a hollow organ to restore or maintain patency if obstructed. It is differentiated from CATHETERIZATION in that the insertion of a catheter is usually performed for the introducing or withdrawing of fluids from the body.
Intubation|intubations|intubation procedures|Intubation, NOS|Intubation - action (qualifier value)|intubation procedure|Intubations|Intubation Procedure|Intubation - action|Intubation (procedure)|intubation|INTUBATION
Intubation
C0019123
Hemorrhage within the pleural cavity.
HEMOTHORAX|HEMORRHAGE PLEURAL|haemothorax|Pleural haemorrhage|Haemothorax|Pleural hemorrhage|PLEURAL HEMORRHAGE|Pleural Hemorrhage|hemothorax|Hemothorax|Hemothorax (disorder)
Hemothorax
C0002878
A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).
Haemolytic anaemia, NOS|hemolytic anemia|haemolytic anaemias|Haemolytic Anaemia|hemolytic anemias|Anaemia, Haemolytic|Hemolytic anemia|Anemia, Hemolytic|Hemolytic anemia (disorder)|Haemolytic Anaemias|ANEMIA HEMOLYTIC (NOS)|Hemolytic Anemia|HEMOLYTIC ANEMIA (NOS)|Increased hemolysis|ANEMIA HEMOLYTIC|ANAEMIA HAEMOLYTIC|haemolytic anaemia|Haemolytic anaemia|Hemolytic anemia, NOS|HEMOLYTIC ANEMIA
Anemia, Hemolytic
C0020402
An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Product containing hydroxycarbamide (medicinal product)|HU|HYD|Hidroxicarbamida|hydroxyurea|Hydroxycarbamid|Hydroxyharnstoff|Carbamyl hydroxamate|Hydroxycarbamide-containing product|Hydroxycarbamide (substance)|N-Hydroxyurea|Carbamohydroximic acid|hyd|Carbamohydroxamic acid|HYDROXYUREA|Oxyurea|Carbamoyl oxime|hydroxycarbamide|hydroxy urea|N-Carbamoylhydroxylamine|Hydroxycarbamide|Hydroxyurea|Hydroxyurea-containing product|Hydroxycarbamidum|Urea, hydroxy-
hydroxyurea
C0279000
Primary liver cancer is cancer that forms in the tissues of the liver. Secondary liver cancer is cancer that spreads to the liver from another part of the body.
Liver Cancer|Cancer of the Liver|liver cancer|Liver and Intrahepatic Bile Duct Carcinoma|liver and intrahepatic bile duct cancer|cancer of liver and intrahepatic biliary tract|liver and intrahepatic biliary tract cancer|cancer of the liver and intrahepatic biliary tract|Liver and hepatobiliary cancer, NOS|Liver and Intrahepatic Bile Duct Cancer|hepatic cancer|Biliary Tract Cancer|Liver and Intrahepatic Biliary Tract Cancer|Cancer of Liver and Intrahepatic Biliary Tract|cancer of the liver|Liver and Intrahepatic Biliary Tract Carcinoma|Cancer of the Liver and Intrahepatic Biliary Tract|Liver/hepatobiliary cancer|liver and intrahepatic bile duct carcinoma|Primary Liver Carcinoma|primary liver carcinoma|cancer of liver|Cancer of Liver
Liver and Intrahepatic Biliary Tract Carcinoma
C1454771
null
PD-184161|PD184161
PD 184161
C0298346
A cell-permeable, selective mitogen-activated protein (MAP) kinase inhibitor which exhibits activity through the inhibition of the phosphorylation and activation of MAP kinase. (NCI)
PD 98059|PD098059|MEK Inhibitor PD-98059|PD 098059|PD98059|PD09859|PD-98059|PD-098059
PD 98059
C0243077
null
null
inhibitors
C1510800
One of a number of genetically-engineered adenoviruses designed to insert a gene of interest into a eukaryotic cell where the gene of interest is subsequently expressed. Unlike most other vectors, adenovirus vectors have the ability to infect post-mitotic cells. Thus, these agents are especially useful for gene transfer into neuronal cells. (NCI04)
Adenoviral Vector|adenovirus vector
Adenovirus Vector
C0678133
brand name of Paclitaxel an anti-cancer drug
Taxol [brand name]|Bris Taxol|Taxol, Bris|Taxol A|Taxol
taxol
C0763620
An Eph family receptor found abundantly in tissues of epithelial origin. It is expressed in a diverse array of tissues during embryonic development, suggesting that it may play a role in embryogenesis. In adult tissues high levels of the receptor are expressed in the LUNG; SKIN; SMALL INTESTINE and OVARY.
EphA2-Tyrosine Kinase|Mammary-Derived Tyrosine Kinase 2|EphA2 Receptor|EphA2 Receptor Tyrosine Kinase|EphA2 Protein|EphA2 Tyrosine Kinase|Mammary Derived Tyrosine Kinase 2|Epithelial Cell Kinase Protein
Receptor, EphA2
C0063700
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
IRF-1 Protein|ISGF1 Transcription Factor|IRF-1 Transcription Factor|MyD32 Protein|IREBF1 Transcription Factor|Transcription Factor, IREBF1|Transcription Factor, IRF-1|Factor, ISGF1 Transcription|Interferon-Stimulated Gene Factor 1|Interferon Regulatory Factor-1|Interferon Stimulated Gene Factor 1|IRF 1 Transcription Factor|Interferon Regulatory Factor 1|IREBF1 Protein|Factor, IRF-1 Transcription|IRF 1 Protein|Transcription Factor, ISGF1
Interferon Regulatory Factor 1
C0063700
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
IRF-1 Protein|ISGF1 Transcription Factor|IRF-1 Transcription Factor|MyD32 Protein|IREBF1 Transcription Factor|Transcription Factor, IREBF1|Transcription Factor, IRF-1|Factor, ISGF1 Transcription|Interferon-Stimulated Gene Factor 1|Interferon Regulatory Factor-1|Interferon Stimulated Gene Factor 1|IRF 1 Transcription Factor|Interferon Regulatory Factor 1|IREBF1 Protein|Factor, IRF-1 Transcription|IRF 1 Protein|Transcription Factor, ISGF1
Interferon Regulatory Factor 1
C0521029
null
null
Reoviral
C0521029
null
null
Reoviral
C1334255
A neoplasm that occurs within the spinal canal in the space between the spinal cord and the dura mater. Representative examples include meningioma, neurofibroma, and sarcoma. Signs and symptoms include local and radicular pain, weakness and spinal cord compression.
Intradural Extramedullary Spinal Canal Tumors|Intradural Extramedullary Tumor of Spinal Canal|Intradural Extramedullary Spinal Neoplasms|Intradural Extramedullary Neoplasm of Spinal Canal|Intradural Extramedullary Spinal Canal Tumor|Intradural Extramedullary Neoplasm of the Spinal Canal|Intradural Extramedullary Spinal Tumors|Intradural Extramedullary Tumor of the Spinal Canal
Intradural Extramedullary Spinal Canal Neoplasm
C1334255
A neoplasm that occurs within the spinal canal in the space between the spinal cord and the dura mater. Representative examples include meningioma, neurofibroma, and sarcoma. Signs and symptoms include local and radicular pain, weakness and spinal cord compression.
Intradural Extramedullary Spinal Canal Tumors|Intradural Extramedullary Tumor of Spinal Canal|Intradural Extramedullary Spinal Neoplasms|Intradural Extramedullary Neoplasm of Spinal Canal|Intradural Extramedullary Spinal Canal Tumor|Intradural Extramedullary Neoplasm of the Spinal Canal|Intradural Extramedullary Spinal Tumors|Intradural Extramedullary Tumor of the Spinal Canal
Intradural Extramedullary Spinal Canal Neoplasm
C0919437
Normal genes, that when altered or inappropriately expressed, contribute to malignant transformation, tumor progression, or metastasis.
genes cancer|Cancer Gene|Gene, Cancer|Cancer-Promoting Gene|Genes, Cancer|cancer genes|Cancer genes|Cancer Genes
Cancer Promoting Genes
C0034243
A group of condensed ring hydrocarbons.
pyrenes|pyrene|Pyrenes
Pyrenes
C0072980
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Sirolimusum|Sirolimús|RAPAMYCIN|sirolimus|(-)-Rapamycin|Sirolimus (substance)|Sirolimus|SLM|RAPA|SIROLIMUS|Sirolimus-containing product|Product containing sirolimus (medicinal product)|Rapamycin|9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,2|rapamycin
sirolimus
C0072667
A parent class of polycyclic aromatic hydrocarbons containing four fused rings. (IUPAC 1998)
Pyrene|pyrene|Benzo(def)phenanthrene|PYRENE
pyrene
C0282460
Works about studies that are usually controlled to assess the effectiveness and dosage (if appropriate) of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques. These studies are performed on several hundred volunteers, including a limited number of patients with the target disease or disorder, and last about two years. This concept includes phase II studies conducted in both the U.S. and in other countries.
Phase II Study|phase ii study|ii phase trials|phase II trial|Phase II Clinical Trial|phase 2|Phase 2 Study|Phase II Protocol|clinical ii phase trials|clinical trials phase 2|2|2 clinical phase trials|PHASE II TRIAL|phase ii clinical trials|phase ii clinical trial|phase ii trial|Clinical Trials, Phase II as Topic|Trial Phase 2|Clinical Trials, Phase II|clinical trial phase II|Phase II Trial|ii phase study
Phase 2 Clinical Trials
C0108793
GPI-linked membrane proteins broadly distributed among hematopoietic and non-hematopoietic cells. CD55 prevents the assembly of C3 CONVERTASE or accelerates the disassembly of preformed convertase, thus blocking the formation of the membrane attack complex.
Decay accelerating factor|DAF - Decay accelerating factor|decay accelerating factor|CD55 Antigens|CD55 Antigen|daf|Cluster of differentiation antigen 55|CD55 antigen|CD55 - Cluster of differentiation antigen 55|Decay-Accelerating Factor, Complement|Complement Decay Accelerating Factor|Decay accelerating factor (substance)|Lymphocyte antigen CD55|Complement Decay-Accelerating Factor|Decay-Accelerating Factor|DAF|Decay Accelerating Factor|Antigens, CD55|CD55
Antigens, CD55
C0007620
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.
cell viability|Cell Survival|Viability, Cell|Survival, Cell|Cell Viabilities|Viabilities, Cell|cell survival|Cell Viability
Cell Survival
C0178679
The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. [ISBN:0471245208]
Tissue Development Process|Histogenesis|tissue development|Histiogenic Process|histogenesis
Histogenic Process
C0000820
Abortion induced to save the life or health of a pregnant woman. (From Dorland, 28th ed)
Therapeutic Abortion Procedure|Therapeutic abortion|Therapeutic abortion procedure (procedure)|Therapeutic Abortions|therapeutic abortion|therapeutic abortions|abortion therapeutic|Abortion, Therapeutic|Abortion, therapeutic|Therapeutic Abortion|abortions therapeutic|Therapeutic abortion procedure, NOS|Therapeutic abortion procedure|Abortions, Therapeutic|Therapeutic termination of pregnancy procedure|Therapeutic abortion NOS
Therapeutic abortion (procedure)
C0597573
null
thiopurine|thiopurines
thiopurine
C0196878
null
neurolysis|nerve destruction|Neurolysis, NOS|Neurolysis (procedure)|destruction nerves
Neurolysis
C0028246
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
Nociceptive Neuron|Nociceptors|Nociceptive Neurons|Receptors, Pain|nociceptors|pain receptors|receptor pain|Pain Receptor|Neuron, Nociceptive|pain receptor|Nociceptor|Pain Receptors|Neurons, Nociceptive|nociceptor
Nociceptors
C0007569
The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.
Celiac artery|Artery, Celiac|Coeliac Artery|Structure of celiac artery|Celiac Arteries|Celiac trunk|Arteries, Celiac|artery celiac|Coeliaco-mesenteric trunk|coeliac axis|celiac trunk|Structure of celiac artery (body structure)|Celiac tree|Coeliac Axis|Haller's tripus|Celiac Axis|CELIAC ARTERY|Celiac Trunk|celiac axis|celiac arteries|celiac artery|coeliac trunk|Truncus coeliacus|Celiac Artery|Structure of coeliac artery|Coeliac Trunk|coeliac artery|Coeliac trunk|Coeliac artery
Celiac Artery
C0006400
A widely used local anesthetic agent.
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide|BUPIVACAINE|bupivacaine|dl-1-Butyl-2',6'-pipecoloxylidide|Product containing bupivacaine (medicinal product)|2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-|1-Butyl-2',6'-pipecoloxylidide|(RS)-bupivacaine|Bupivacaine (substance)|Bupivacaine|Bupivacaina|DL-Bupivacaine|(±)-bupivacaine|(-)-bupivacaine|racemic bupivacaine|Bupivacaine-containing product|Bupivacainum
bupivacaine
C0040864
A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)
(11beta,16alpha)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione|triamcinolone|Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)-|Triamcinolona|Product containing triamcinolone (medicinal product)|Fluoxyprednisolone|Triamcinolone (substance)|Triamcinolone preparation|Triamcinolonum|(11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione|Triamcinolone|Tiamcinolonum|TRIAMCINOLONE|9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione|11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione|9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione|9α-fluoro-16α-hydroxyprednisolone|9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione|Triamcinolone-containing product
triamcinolone
C0070570
An antiseptic and disinfectant aromatic alcohol.
Oxybenzene|Phenol-containing product|Karbolsäure|Acide carbolique|Carbolsäure|Phenol, NOS|Phenylic acid|Product containing phenol (medicinal product)|Phenol (substance)|Carbol|Phenol|Fenol|Phenyl hydroxide|Phenylic Acid|Phenylic alcohol|Hydroxybenzene|PHENOL|Phenyl alcohol|Benzenol|Carbolic Acid|carbolic acid|oxybenzene|phenol|Carbolic acid|PHOH|Phenic acid|Monohydroxybenzene|Phenic Acid|Acide phénique
phenol
C1608241
null
Ganglionectomy|Excision of ganglion site, NOS|Excision of ganglion cyst (procedure)|Excision of ganglion cyst|Excision of ganglion|Excision of ganglion site
Excision of musculoskeletal ganglion site
C0341490
null
Pancreatic duct stricture (disorder)
Pancreatic duct stricture
C1280889
null
Entire bile duct (body structure)|Entire bile duct
Entire bile duct
C0441289
null
Plastic stent (physical object)
Plastic stent
C0948160
An infectious process affecting the pancreas.
infections pancreas|pancreas infection|Pancreas infection|Pancreatic Infection|infection pancreas
Pancreatic Infection
C0267941
A severe form of acute INFLAMMATION of the PANCREAS characterized by one or more areas of NECROSIS in the pancreas with varying degree of involvement of the surrounding tissues or organ systems. Massive pancreatic necrosis may lead to DIABETES MELLITUS, and malabsorption.
Pancreatitis Necrotizings|NECROTIZING PANCREATITIS|acute necrotising pancreatitis|Pancreatitis Necrotising|Pancreatitis Necrotizing|Pancreatitis Necrotisings|Acute necrotizing pancreatitis (disorder)|necrotizing pancreatitis|PANCREATITIS NECROTIZING|Necrotizing Pancreatitis, Acute|Necrotising pancreatitis|necrotising pancreatitis|Necrosis, Pancreatic|Acute necrotising pancreatitis|acute necrotizing pancreatitis|Pancreatic Necroses|Acute Necrotizing Pancreatitis|Pancreatic Necrosis|Necrotizing pancreatitis|Acute necrotizing pancreatitis|Pancreatitis, Acute Necrotizing
Pancreatitis Necrotizing
C0267953
A necrotic process affecting the pancreas.
Pancreatic Necrotic Lesion|necrosis pancreas|Necrosis of pancreas|Necrosis of pancreas (disorder)|pancreatic necrosis|Pancreatic necrosis|pancreas necrosis|necrosis of pancreas|Pancreatic necrosis NOS
Necrosis of pancreas
C0011079
The removal of foreign material and devitalized or contaminated tissue from or adjacent to a traumatic or infected lesion until surrounding healthy tissue is exposed. (Dorland, 27th ed)
Debridement NOS|Debridement - action|Debridement|debridements|Debridement (procedure)|Debridements|Debridement, NOS|debridement|Debridement - action (qualifier value)
Debridement
C0030291
Tests based on the biochemistry and physiology of the exocrine pancreas and involving analysis of blood, duodenal contents, feces, or urine for products of pancreatic secretion.
Function Tests, Pancreatic|pancreatic function test|Pancreatic Function Test|Tests, Pancreatic Function|pancreatic function tests|Pancreatic Function Tests|Test, Pancreatic Function|Pancreatic function test (procedure)|Function Test, Pancreatic|Pancreatic function test
Pancreatic Function Test
C0393293
performing dilating a narrow passage via endoscope
endoscopic dilation|Endoscopic dilation|endoscopic dilatation|Endoscopic dilation (procedure)
Endoscopic dilatation
C0566602
A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.
Primary sclerosing cholangitis (disorder)|sclerosing cholangitis|Cholangitides, Primary Sclerosing|CHOLANGITIS, PRIMARY SCLEROSING|Primary Sclerosing Cholangitis (PSC)|Primary Sclerosing Cholangitides|PSC|Cholangitis, Primary Sclerosing|cholangitis primary sclerosing|Primary Sclerosing Cholangitis|Sclerosing Cholangitis, Primary|primary sclerosing cholangitis|Sclerosing Cholangitides, Primary|Sclerosing Cholangitis|PSC - Primary sclerosing cholangitis|Primary sclerosing cholangitis
Primary sclerosing cholangitis
C0008311
Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.
Biliary tract infection|cholangeitis|INFLAMMATION BILE DUCT|bile duct inflammation|Cholangitis, NOS|Biliary Tract Infection|Cholangitides|Cholangitis|Cholangitis (disorder)|CHOLANGITIS|Cholangitis NOS|Bile duct inflammation|cholangitis
Cholangitis
C0023895
Pathological processes of the LIVER.
Hepatic disease|liver disorders|hepatic disease|LIVER DISEASE|Liver disease|disease of liver|Unspecified disorder of liver|Disease of liver|Disorder of liver|Disease of liver, NOS|LIVER DISORDER|Hepatic Diseases|Liver and Intrahepatic Bile Duct Disorder|FECTOR HEPATICUS|Hepatopathy|Diseases, Liver|LD - Liver disease|Liver disease, NOS|hepatic disorder|Hepatic Disorder|hepatopathy|DISEASES OF THE LIVER|DISEASE HEPATOCELLULAR|Disease, Liver|Liver Disorder|hepatic disorders|HEPATIC DISEASE (NOS)|Liver Disease|liver diseases of|fector hepaticus|diseases of the liver|hepatocellular disease|Disorder of liver (disorder)|liver diseases|DISORDER HEPATIC|DISORDER LIVER|HEPATIC: HEPATOCELLULAR|liver disorder|diseases of liver|Liver--Diseases|liver disease|HEPATIC DISORDER (NOS)|Liver Diseases
Liver diseases
C0597984
null
Biliary stricture (disorder)|bile stricture|Biliary system stenosis|biliary stricture|bile strictures|Biliary stricture|biliary stenosis or stricture|biliary strictures
Biliary stricture
C0176940
Removal of the body and tail of the pancreas.
Distal pancreatectomy|Distal Pancreatectomy|Partial distal subtotal pancreatectomy|Distal subtotal pancreatectomy (procedure)|Distal subtotal pancreatectomy|DP - Distal pancreatectomy|distal pancreatectomy
Distal subtotal pancreatectomy
C0348025
null
opening surgery|Open approach|invasive procedure|open surgery|Open approach - access (qualifier value)|Open approach - access|Invasive procedure|Open surgery
Open approach
C0037995
Surgical procedure involving either partial or entire removal of the spleen.
SPLENECTOMY|splenectomies|excision of the spleen|splenectomy|Splenectomy (procedure)|Excision of spleen tissue|Splenectomies|Splenectomy NOS|Splenectomy
Splenectomy
C0085162
The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.
operation whipples|duodenopancreatectomy|Whipple Procedure|whipples procedure|Pancreaticoduodenectomy|Pancreatoduodenectomy|Duodenopancreatectomy|Whipple procedure|Pancreaticoduodenectomies|procedures whipple|Duodenopancreatectomies|whipple procedure|whipple's operation|Pancreaticoduodenectomy (procedure)|pancreaticoduodenectomy|Pancreatoduodenectomies|whipple operation|Whipple operation|procedure whipple|Whipple operation, proximal pancreatectomy|pancreatoduodenectomy
Pancreaticoduodenectomy
C0153452
A primary or metastatic malignant neoplasm that affects the gallbladder. Representative examples include carcinoma, lymphoma, melanoma, and sarcoma.
Malignant Neoplasm of Gallbladder|Malignant Gallbladder Neoplasm|Cancer of the Gallbladder|Gall Bladder Cancer|Gallbladder Cancers|Gallbladder Ca|Malignant tumor of gallbladder|gallbladder malignant neoplasm|Cancers, Gall Bladder|gallbladder tumor or cancer|gallbladder cancers|Gallbladder Cancer|Gall Bladder Cancers|Gallbladder--Cancer|Cancer, Gall Bladder|Cancer, Gallbladder|Malignant Gallbladder Tumor|of gallbladder cancer|Malignant neoplasm of gallbladder|gallbladder cancer|cancer gallbladder|Malignant Tumor of Gallbladder|Bladder Cancer, Gall|Malignant tumour of gallbladder|Bladder Cancers, Gall|cancer of the gallbladder|Malignant Tumor of the Gallbladder|Malignant tumor of gallbladder (disorder)|Malignant Neoplasm of the Gallbladder|Cancers, Gallbladder|Gallbladder cancer|gallbladder ca|Cancer of Gallbladder
Malignant neoplasm of gallbladder
C0008320
Surgical removal of the GALLBLADDER.
Excision of gallbladder|Cholecystectomy (procedure)|cholecystectomies|gallbladder removal|excision of gallbladder|surgical removal of the gallbladder|Gallbladder excision|cholecystectomy procedure|removal of gallbladder|CHOLECYSTECTOMY|Cholecystectomies|Removal of gallbladder|cholecystectomy|Cholecystectomy
Cholecystectomy procedure
C0441290
null
metal stent|Metal stent (physical object)|metal stents
Metal stent
C0038257
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
Stent|stents|Stent Device|stented|stent|Stent, NOS|Stent, device (physical object)|stenting|Stent, device|Stents
Stent, device