id
stringlengths 5
8
| document_id
stringlengths 8
8
| passages
list | entities
list | events
list | coreferences
list | relations
list |
---|---|---|---|---|---|---|
DS.d723 | 18687985 | [
{
"id": "DS.d723.s0",
"type": "",
"text": [
"Studies suggest that DKK1 activation in osteoblasts is the underlying cause of glucocorticoid- and estrogen deficiency-mediated osteoporosis, and at least partially underlies the teratogenic effects of thalidomide on limb development."
],
"offsets": [
[
0,
234
]
]
}
] | [
{
"id": "DS.d723.s0.e0",
"type": "protein",
"text": [
"DKK1"
],
"offsets": [
[
21,
25
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O94907"
}
]
},
{
"id": "DS.d723.s0.e1",
"type": "compound",
"text": [
"thalidomide"
],
"offsets": [
[
202,
213
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5426"
},
{
"db_name": "PubChem",
"db_id": "75792"
},
{
"db_name": "PubChem",
"db_id": "92142"
}
]
}
] | [] | [] | [
{
"id": "DS.d723.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d723.s0.e1",
"arg2_id": "DS.d723.s0.e0",
"normalized": []
}
] |
DS.d724 | 18688040 | [
{
"id": "DS.d724.s0",
"type": "",
"text": [
"The IL-13-induced up-regulation of RhoA was inhibited by leflunomide, an inhibitor of signal transducer and activator of transcription 6 (STAT6)."
],
"offsets": [
[
0,
145
]
]
}
] | [
{
"id": "DS.d724.s0.e0",
"type": "protein",
"text": [
"IL-13"
],
"offsets": [
[
4,
9
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P20109"
},
{
"db_name": "UniProt",
"db_id": "P35225"
},
{
"db_name": "UniProt",
"db_id": "P42203"
},
{
"db_name": "UniProt",
"db_id": "P61126"
},
{
"db_name": "UniProt",
"db_id": "Q5I6E4"
},
{
"db_name": "UniProt",
"db_id": "Q864V6"
},
{
"db_name": "UniProt",
"db_id": "Q865W5"
},
{
"db_name": "UniProt",
"db_id": "Q865X3"
},
{
"db_name": "UniProt",
"db_id": "Q95J68"
},
{
"db_name": "UniProt",
"db_id": "Q9N0W9"
},
{
"db_name": "UniProt",
"db_id": "Q9XSV9"
}
]
},
{
"id": "DS.d724.s0.e1",
"type": "protein",
"text": [
"RhoA"
],
"offsets": [
[
35,
39
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q9C3Y4"
}
]
},
{
"id": "DS.d724.s0.e2",
"type": "compound",
"text": [
"leflunomide"
],
"offsets": [
[
57,
68
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3899"
}
]
},
{
"id": "DS.d724.s0.e3",
"type": "protein",
"text": [
"STAT6"
],
"offsets": [
[
138,
143
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P42226"
}
]
}
] | [] | [] | [
{
"id": "DS.d724.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d724.s0.e2",
"arg2_id": "DS.d724.s0.e1",
"normalized": []
},
{
"id": "DS.d724.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d724.s0.e2",
"arg2_id": "DS.d724.s0.e3",
"normalized": []
}
] |
DS.d725 | 18688042 | [
{
"id": "DS.d725.s0",
"type": "",
"text": [
"The goal of this study was to determine the mechanisms by which 17beta-estradiol induces MUC5B gene expression in airway epithelial cells."
],
"offsets": [
[
0,
138
]
]
},
{
"id": "DS.d725.s1",
"type": "",
"text": [
"Pretreatment with ER antagonist ICI 182,780 blocked both E2-induced ERK1/2-MAPK activation and MUC5B gene expression."
],
"offsets": [
[
139,
256
]
]
}
] | [
{
"id": "DS.d725.s0.e0",
"type": "compound",
"text": [
"17beta-estradiol"
],
"offsets": [
[
64,
80
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5757"
}
]
},
{
"id": "DS.d725.s0.e1",
"type": "protein",
"text": [
"MUC5B"
],
"offsets": [
[
89,
94
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q9HC84"
}
]
},
{
"id": "DS.d725.s1.e0",
"type": "compound",
"text": [
"ICI 182,780"
],
"offsets": [
[
171,
182
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "104741"
}
]
},
{
"id": "DS.d725.s1.e1",
"type": "protein",
"text": [
"ERK1"
],
"offsets": [
[
207,
211
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P27361"
},
{
"db_name": "UniProt",
"db_id": "P28869"
},
{
"db_name": "UniProt",
"db_id": "P42525"
},
{
"db_name": "UniProt",
"db_id": "Q07176"
}
]
},
{
"id": "DS.d725.s1.e2",
"type": "protein",
"text": [
"MAPK"
],
"offsets": [
[
214,
218
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O42781"
},
{
"db_name": "UniProt",
"db_id": "P27638"
},
{
"db_name": "UniProt",
"db_id": "Q00859"
}
]
},
{
"id": "DS.d725.s1.e3",
"type": "protein",
"text": [
"MUC5B"
],
"offsets": [
[
234,
239
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q9HC84"
}
]
}
] | [] | [] | [
{
"id": "DS.d725.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d725.s0.e0",
"arg2_id": "DS.d725.s0.e1",
"normalized": []
},
{
"id": "DS.d725.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d725.s1.e0",
"arg2_id": "DS.d725.s1.e1",
"normalized": []
},
{
"id": "DS.d725.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d725.s1.e0",
"arg2_id": "DS.d725.s1.e2",
"normalized": []
},
{
"id": "DS.d725.s1.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d725.s1.e0",
"arg2_id": "DS.d725.s1.e3",
"normalized": []
}
] |
DS.d726 | 18688696 | [
{
"id": "DS.d726.s0",
"type": "",
"text": [
"We here show that calumenin in the presence of Ca(2+) binds to TSP1 with a dissociation constant K (d) around 0.4 muM."
],
"offsets": [
[
0,
118
]
]
}
] | [
{
"id": "DS.d726.s0.e0",
"type": "compound",
"text": [
"Ca(2"
],
"offsets": [
[
47,
51
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "271"
}
]
},
{
"id": "DS.d726.s0.e1",
"type": "protein",
"text": [
"TSP1"
],
"offsets": [
[
63,
67
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P07996"
},
{
"db_name": "UniProt",
"db_id": "P54000"
},
{
"db_name": "UniProt",
"db_id": "Q28178"
}
]
}
] | [] | [] | [
{
"id": "DS.d726.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d726.s0.e0",
"arg2_id": "DS.d726.s0.e1",
"normalized": []
}
] |
DS.d727 | 18688816 | [
{
"id": "DS.d727.s0",
"type": "",
"text": [
"It represents transition in sulfur-deprived conditions, known to lead to H2 production in Chlamydomonas reinhardtii, and the two main processes then induced which are an over-accumulation of intracellular starch and a progressive reduction of PSII activity for anoxia achievement."
],
"offsets": [
[
0,
280
]
]
}
] | [
{
"id": "DS.d727.s0.e0",
"type": "compound",
"text": [
"sulfur"
],
"offsets": [
[
28,
34
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "402"
}
]
},
{
"id": "DS.d727.s0.e1",
"type": "protein",
"text": [
"PSII"
],
"offsets": [
[
243,
247
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O47040"
},
{
"db_name": "UniProt",
"db_id": "O78462"
},
{
"db_name": "UniProt",
"db_id": "O96813"
},
{
"db_name": "UniProt",
"db_id": "P12185"
},
{
"db_name": "UniProt",
"db_id": "P12186"
},
{
"db_name": "UniProt",
"db_id": "P12187"
},
{
"db_name": "UniProt",
"db_id": "P13165"
},
{
"db_name": "UniProt",
"db_id": "P17227"
},
{
"db_name": "UniProt",
"db_id": "P17228"
},
{
"db_name": "UniProt",
"db_id": "P28251"
},
{
"db_name": "UniProt",
"db_id": "P30980"
},
{
"db_name": "UniProt",
"db_id": "P48116"
},
{
"db_name": "UniProt",
"db_id": "P49159"
},
{
"db_name": "UniProt",
"db_id": "P49484"
},
{
"db_name": "UniProt",
"db_id": "P51387"
},
{
"db_name": "UniProt",
"db_id": "P52768"
},
{
"db_name": "UniProt",
"db_id": "P56768"
},
{
"db_name": "UniProt",
"db_id": "P58214"
},
{
"db_name": "UniProt",
"db_id": "P69396"
},
{
"db_name": "UniProt",
"db_id": "P69397"
},
{
"db_name": "UniProt",
"db_id": "P69398"
},
{
"db_name": "UniProt",
"db_id": "Q31909"
},
{
"db_name": "UniProt",
"db_id": "Q5QA78"
},
{
"db_name": "UniProt",
"db_id": "Q5SCW1"
},
{
"db_name": "UniProt",
"db_id": "Q68RZ6"
},
{
"db_name": "UniProt",
"db_id": "Q6B8K8"
},
{
"db_name": "UniProt",
"db_id": "Q6ENG4"
},
{
"db_name": "UniProt",
"db_id": "Q6ENV4"
},
{
"db_name": "UniProt",
"db_id": "Q6EW69"
},
{
"db_name": "UniProt",
"db_id": "Q6L390"
},
{
"db_name": "UniProt",
"db_id": "Q6L603"
},
{
"db_name": "UniProt",
"db_id": "Q6QBN9"
},
{
"db_name": "UniProt",
"db_id": "Q70XZ3"
},
{
"db_name": "UniProt",
"db_id": "Q7FNS8"
},
{
"db_name": "UniProt",
"db_id": "Q7YJW3"
},
{
"db_name": "UniProt",
"db_id": "Q85CI4"
},
{
"db_name": "UniProt",
"db_id": "Q85FL2"
},
{
"db_name": "UniProt",
"db_id": "Q85X26"
},
{
"db_name": "UniProt",
"db_id": "Q8M9X5"
},
{
"db_name": "UniProt",
"db_id": "Q8WI10"
},
{
"db_name": "UniProt",
"db_id": "Q9BBS0"
},
{
"db_name": "UniProt",
"db_id": "Q9GDV2"
},
{
"db_name": "UniProt",
"db_id": "Q9MTL2"
},
{
"db_name": "UniProt",
"db_id": "Q9MUQ4"
},
{
"db_name": "UniProt",
"db_id": "Q9TL12"
},
{
"db_name": "UniProt",
"db_id": "Q9TM24"
}
]
}
] | [] | [] | [
{
"id": "DS.d727.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d727.s0.e0",
"arg2_id": "DS.d727.s0.e1",
"normalized": []
}
] |
DS.d728 | 18689429 | [
{
"id": "DS.d728.s0",
"type": "",
"text": [
"We examined whether aldosterone produced locally in the brain may contribute to the activation of mineralocorticoid receptors in the CNS."
],
"offsets": [
[
0,
137
]
]
}
] | [
{
"id": "DS.d728.s0.e0",
"type": "compound",
"text": [
"aldosterone"
],
"offsets": [
[
20,
31
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5839"
}
]
},
{
"id": "DS.d728.s0.e1",
"type": "protein",
"text": [
"mineralocorticoid receptors"
],
"offsets": [
[
98,
125
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P08235"
},
{
"db_name": "UniProt",
"db_id": "P22199"
},
{
"db_name": "UniProt",
"db_id": "P79404"
},
{
"db_name": "UniProt",
"db_id": "Q29131"
},
{
"db_name": "UniProt",
"db_id": "Q3YC04"
},
{
"db_name": "UniProt",
"db_id": "Q4JM28"
},
{
"db_name": "UniProt",
"db_id": "Q8QHI2"
},
{
"db_name": "UniProt",
"db_id": "Q8VII8"
},
{
"db_name": "UniProt",
"db_id": "Q91573"
},
{
"db_name": "UniProt",
"db_id": "Q9BDJ7"
},
{
"db_name": "UniProt",
"db_id": "Q9IAC6"
},
{
"db_name": "UniProt",
"db_id": "Q9N0W8"
}
]
}
] | [] | [] | [
{
"id": "DS.d728.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d728.s0.e0",
"arg2_id": "DS.d728.s0.e1",
"normalized": []
}
] |
DS.d729 | 18690415 | [
{
"id": "DS.d729.s0",
"type": "",
"text": [
"Macrophages isolated from iron deficient rats, or pregnant rats at day 21 of gestation, either supplemented with a single dose of iron dextran, 10 mg, at the commencement of pregnancy, or not, showed significant increases of macrophage ferroportin mRNA expression, which was paralleled by significant decreases in hepatic Hamp mRNA expression."
],
"offsets": [
[
0,
343
]
]
}
] | [
{
"id": "DS.d729.s0.e0",
"type": "compound",
"text": [
"iron dextran"
],
"offsets": [
[
130,
142
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "105075"
}
]
},
{
"id": "DS.d729.s0.e1",
"type": "protein",
"text": [
"Hamp"
],
"offsets": [
[
322,
326
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q7T273"
},
{
"db_name": "UniProt",
"db_id": "Q99MH3"
},
{
"db_name": "UniProt",
"db_id": "Q9EQ21"
}
]
}
] | [] | [] | [
{
"id": "DS.d729.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d729.s0.e0",
"arg2_id": "DS.d729.s0.e1",
"normalized": []
}
] |
DS.d730 | 18690549 | [
{
"id": "DS.d730.s0",
"type": "",
"text": [
"Rat dicarboxylate transporter (SDCT1), expressed in renal tubular epithelial cells, plays a key role in regulating blood and urinary citrate level by reabsorbing citrate from the lumen."
],
"offsets": [
[
0,
185
]
]
}
] | [
{
"id": "DS.d730.s0.e0",
"type": "protein",
"text": [
"SDCT1"
],
"offsets": [
[
31,
36
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q13183"
},
{
"db_name": "UniProt",
"db_id": "Q28615"
}
]
},
{
"id": "DS.d730.s0.e1",
"type": "compound",
"text": [
"citrate"
],
"offsets": [
[
133,
140
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "311"
},
{
"db_name": "PubChem",
"db_id": "2733526"
}
]
},
{
"id": "DS.d730.s0.e2",
"type": "compound",
"text": [
"citrate"
],
"offsets": [
[
162,
169
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "311"
},
{
"db_name": "PubChem",
"db_id": "2733526"
}
]
}
] | [] | [] | [
{
"id": "DS.d730.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d730.s0.e1",
"arg2_id": "DS.d730.s0.e0",
"normalized": []
}
] |
DS.d731 | 18690792 | [
{
"id": "DS.d731.s0",
"type": "",
"text": [
"However, as opposed to exogenous HS, the continuous use of FGF-2 during in vitro differentiation completely blocked rMSC mineralization."
],
"offsets": [
[
0,
136
]
]
},
{
"id": "DS.d731.s1",
"type": "",
"text": [
"We show that the effects of both FGF-2 and HS are mediated through FGF receptor 1 (FGFR1) and that inhibition of signaling through this receptor arrests cell growth, resulting in the cells being unable to reach the critical density necessary to induce differentiation."
],
"offsets": [
[
137,
405
]
]
}
] | [
{
"id": "DS.d731.s0.e0",
"type": "compound",
"text": [
"HS"
],
"offsets": [
[
33,
35
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5047209"
},
{
"db_name": "PubChem",
"db_id": "46173182"
}
]
},
{
"id": "DS.d731.s0.e1",
"type": "protein",
"text": [
"FGF-2"
],
"offsets": [
[
59,
64
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P03969"
},
{
"db_name": "UniProt",
"db_id": "P20003"
},
{
"db_name": "UniProt",
"db_id": "P48800"
},
{
"db_name": "UniProt",
"db_id": "Q60487"
}
]
},
{
"id": "DS.d731.s1.e0",
"type": "protein",
"text": [
"FGF-2"
],
"offsets": [
[
170,
175
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P03969"
},
{
"db_name": "UniProt",
"db_id": "P20003"
},
{
"db_name": "UniProt",
"db_id": "P48800"
},
{
"db_name": "UniProt",
"db_id": "Q60487"
}
]
},
{
"id": "DS.d731.s1.e1",
"type": "compound",
"text": [
"HS"
],
"offsets": [
[
180,
182
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5047209"
},
{
"db_name": "PubChem",
"db_id": "46173182"
}
]
},
{
"id": "DS.d731.s1.e2",
"type": "protein",
"text": [
"FGF"
],
"offsets": [
[
170,
173
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O10284"
},
{
"db_name": "UniProt",
"db_id": "P41444"
}
]
},
{
"id": "DS.d731.s1.e3",
"type": "protein",
"text": [
"FGFR1"
],
"offsets": [
[
220,
225
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P11362"
},
{
"db_name": "UniProt",
"db_id": "P21804"
},
{
"db_name": "UniProt",
"db_id": "Q8MY86"
},
{
"db_name": "UniProt",
"db_id": "Q91285"
}
]
}
] | [] | [] | [
{
"id": "DS.d731.s1.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d731.s1.e1",
"arg2_id": "DS.d731.s1.e3",
"normalized": []
}
] |
DS.d732 | 18691156 | [
{
"id": "DS.d732.s0",
"type": "",
"text": [
"Two related polytopic membrane proteins of the major facilitator family, NarK and NarU, catalyse nitrate uptake, nitrite export and nitrite uptake across the Escherichia coli cytoplasmic membrane by an unknown mechanism."
],
"offsets": [
[
0,
220
]
]
}
] | [
{
"id": "DS.d732.s0.e0",
"type": "protein",
"text": [
"membrane proteins"
],
"offsets": [
[
22,
39
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P16629"
},
{
"db_name": "UniProt",
"db_id": "P24266"
},
{
"db_name": "UniProt",
"db_id": "P28991"
},
{
"db_name": "UniProt",
"db_id": "Q04565"
},
{
"db_name": "UniProt",
"db_id": "Q07252"
}
]
},
{
"id": "DS.d732.s0.e1",
"type": "protein",
"text": [
"NarK"
],
"offsets": [
[
73,
77
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10903"
},
{
"db_name": "UniProt",
"db_id": "P46907"
}
]
},
{
"id": "DS.d732.s0.e2",
"type": "protein",
"text": [
"NarU"
],
"offsets": [
[
82,
86
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P37593"
},
{
"db_name": "UniProt",
"db_id": "P37758"
}
]
},
{
"id": "DS.d732.s0.e3",
"type": "compound",
"text": [
"nitrate"
],
"offsets": [
[
97,
104
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "943"
}
]
}
] | [] | [] | [
{
"id": "DS.d732.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d732.s0.e3",
"arg2_id": "DS.d732.s0.e2",
"normalized": []
},
{
"id": "DS.d732.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d732.s0.e3",
"arg2_id": "DS.d732.s0.e1",
"normalized": []
}
] |
DS.d733 | 18691343 | [
{
"id": "DS.d733.s0",
"type": "",
"text": [
"Intracellular interleukin-4 (Th2 cytokine) and interferon-gamma (Th1 cytokine) production was assessed in CD4+ T lymphocytes activated by phorbol 12-myristate 13-acetate and ionomycin using flow cytometry."
],
"offsets": [
[
0,
205
]
]
}
] | [
{
"id": "DS.d733.s0.e0",
"type": "protein",
"text": [
"interferon-gamma"
],
"offsets": [
[
47,
63
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q9TTB0"
}
]
},
{
"id": "DS.d733.s0.e1",
"type": "protein",
"text": [
"Th1"
],
"offsets": [
[
65,
68
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q64279"
},
{
"db_name": "UniProt",
"db_id": "Q922L6"
}
]
},
{
"id": "DS.d733.s0.e2",
"type": "compound",
"text": [
"phorbol 12-myristate 13-acetate"
],
"offsets": [
[
138,
169
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4792"
},
{
"db_name": "PubChem",
"db_id": "27924"
},
{
"db_name": "PubChem",
"db_id": "122634"
},
{
"db_name": "PubChem",
"db_id": "22833501"
}
]
},
{
"id": "DS.d733.s0.e3",
"type": "compound",
"text": [
"ionomycin"
],
"offsets": [
[
174,
183
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3733"
},
{
"db_name": "PubChem",
"db_id": "6434517"
},
{
"db_name": "PubChem",
"db_id": "6912226"
},
{
"db_name": "PubChem",
"db_id": "25134244"
}
]
}
] | [] | [] | [
{
"id": "DS.d733.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d733.s0.e3",
"arg2_id": "DS.d733.s0.e0",
"normalized": []
},
{
"id": "DS.d733.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d733.s0.e2",
"arg2_id": "DS.d733.s0.e1",
"normalized": []
},
{
"id": "DS.d733.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d733.s0.e2",
"arg2_id": "DS.d733.s0.e0",
"normalized": []
},
{
"id": "DS.d733.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d733.s0.e3",
"arg2_id": "DS.d733.s0.e1",
"normalized": []
}
] |
DS.d734 | 18691603 | [
{
"id": "DS.d734.s0",
"type": "",
"text": [
"This signaling system is engaged by the active component of cannabis, Delta9-tetrahydrocannabinol (Delta9-THC), which exerts its pharmacological effects by activation of G protein-coupled type-1 (CB1) and type-2 (CB2) cannabinoid receptors."
],
"offsets": [
[
0,
240
]
]
}
] | [
{
"id": "DS.d734.s0.e0",
"type": "compound",
"text": [
"Delta9-tetrahydrocannabinol"
],
"offsets": [
[
70,
97
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "16078"
}
]
},
{
"id": "DS.d734.s0.e1",
"type": "compound",
"text": [
"Delta9-THC"
],
"offsets": [
[
99,
109
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "16078"
}
]
},
{
"id": "DS.d734.s0.e2",
"type": "protein",
"text": [
"CB1"
],
"offsets": [
[
196,
199
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O02777"
},
{
"db_name": "UniProt",
"db_id": "P20272"
},
{
"db_name": "UniProt",
"db_id": "P21554"
},
{
"db_name": "UniProt",
"db_id": "P47746"
},
{
"db_name": "UniProt",
"db_id": "P56971"
},
{
"db_name": "UniProt",
"db_id": "Q333S9"
},
{
"db_name": "UniProt",
"db_id": "Q5IS73"
},
{
"db_name": "UniProt",
"db_id": "Q71SP5"
},
{
"db_name": "UniProt",
"db_id": "Q801M1"
},
{
"db_name": "UniProt",
"db_id": "Q9PUI7"
}
]
},
{
"id": "DS.d734.s0.e3",
"type": "protein",
"text": [
"CB2"
],
"offsets": [
[
213,
216
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P34972"
},
{
"db_name": "UniProt",
"db_id": "P47936"
},
{
"db_name": "UniProt",
"db_id": "Q9QZN9"
}
]
}
] | [] | [] | [
{
"id": "DS.d734.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d734.s0.e1",
"arg2_id": "DS.d734.s0.e3",
"normalized": []
},
{
"id": "DS.d734.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d734.s0.e0",
"arg2_id": "DS.d734.s0.e3",
"normalized": []
},
{
"id": "DS.d734.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d734.s0.e0",
"arg2_id": "DS.d734.s0.e2",
"normalized": []
},
{
"id": "DS.d734.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d734.s0.e1",
"arg2_id": "DS.d734.s0.e2",
"normalized": []
}
] |
DS.d735 | 18691715 | [
{
"id": "DS.d735.s0",
"type": "",
"text": [
"Homocysteine stimulates antioxidant response element-mediated expression of glutamate-cysteine ligase in mouse macrophages."
],
"offsets": [
[
0,
123
]
]
},
{
"id": "DS.d735.s1",
"type": "",
"text": [
"The current study investigated whether homocysteine induces transcription of glutamate-cysteine ligase (Gcl), via ARE driven gene expression in mouse macrophages."
],
"offsets": [
[
124,
286
]
]
},
{
"id": "DS.d735.s2",
"type": "",
"text": [
"Treatment of mouse macrophages with d-/l-homocysteine (50microM) induced depletion of intracellular glutathione and a compensatory increase in Gcl activity."
],
"offsets": [
[
287,
443
]
]
},
{
"id": "DS.d735.s3",
"type": "",
"text": [
"Real-time RT-PCR revealed increased mRNA-expression of the catalytic subunit of Gcl (Gclc) after treatment with homocysteine, and this occurred via increased transcription as demonstrated with luciferase promoter reporter constructs for Gclc."
],
"offsets": [
[
444,
686
]
]
}
] | [
{
"id": "DS.d735.s0.e0",
"type": "compound",
"text": [
"Homocysteine"
],
"offsets": [
[
0,
12
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "778"
}
]
},
{
"id": "DS.d735.s0.e1",
"type": "protein",
"text": [
"glutamate-cysteine ligase"
],
"offsets": [
[
76,
101
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O68838"
},
{
"db_name": "UniProt",
"db_id": "P0A6W9"
},
{
"db_name": "UniProt",
"db_id": "P0A6X0"
},
{
"db_name": "UniProt",
"db_id": "P32477"
},
{
"db_name": "UniProt",
"db_id": "P57485"
},
{
"db_name": "UniProt",
"db_id": "P58994"
},
{
"db_name": "UniProt",
"db_id": "P61379"
},
{
"db_name": "UniProt",
"db_id": "Q09768"
},
{
"db_name": "UniProt",
"db_id": "Q20117"
},
{
"db_name": "UniProt",
"db_id": "Q57KV3"
},
{
"db_name": "UniProt",
"db_id": "Q5E7F8"
},
{
"db_name": "UniProt",
"db_id": "Q5LYY5"
},
{
"db_name": "UniProt",
"db_id": "Q5M3J8"
},
{
"db_name": "UniProt",
"db_id": "Q5PF10"
},
{
"db_name": "UniProt",
"db_id": "Q65RX0"
},
{
"db_name": "UniProt",
"db_id": "Q66E64"
},
{
"db_name": "UniProt",
"db_id": "Q6ANW2"
},
{
"db_name": "UniProt",
"db_id": "Q6D1T4"
},
{
"db_name": "UniProt",
"db_id": "Q6LMV1"
},
{
"db_name": "UniProt",
"db_id": "Q71VZ1"
},
{
"db_name": "UniProt",
"db_id": "Q72RD4"
},
{
"db_name": "UniProt",
"db_id": "Q7MHS5"
},
{
"db_name": "UniProt",
"db_id": "Q7N7A4"
},
{
"db_name": "UniProt",
"db_id": "Q7W3F2"
},
{
"db_name": "UniProt",
"db_id": "Q7WES2"
},
{
"db_name": "UniProt",
"db_id": "Q82ZG8"
},
{
"db_name": "UniProt",
"db_id": "Q87LS2"
},
{
"db_name": "UniProt",
"db_id": "Q88AR1"
},
{
"db_name": "UniProt",
"db_id": "Q88R90"
},
{
"db_name": "UniProt",
"db_id": "Q88UW5"
},
{
"db_name": "UniProt",
"db_id": "Q89AD8"
},
{
"db_name": "UniProt",
"db_id": "Q8D2V5"
},
{
"db_name": "UniProt",
"db_id": "Q8DC38"
},
{
"db_name": "UniProt",
"db_id": "Q8DW15"
},
{
"db_name": "UniProt",
"db_id": "Q8DXM9"
},
{
"db_name": "UniProt",
"db_id": "Q8E399"
},
{
"db_name": "UniProt",
"db_id": "Q8EBF9"
},
{
"db_name": "UniProt",
"db_id": "Q8F4D5"
},
{
"db_name": "UniProt",
"db_id": "Q8X0X0"
},
{
"db_name": "UniProt",
"db_id": "Q8X900"
},
{
"db_name": "UniProt",
"db_id": "Q8XK30"
},
{
"db_name": "UniProt",
"db_id": "Q8Y3R3"
},
{
"db_name": "UniProt",
"db_id": "Q8Z4D6"
},
{
"db_name": "UniProt",
"db_id": "Q8ZBU2"
},
{
"db_name": "UniProt",
"db_id": "Q926X7"
},
{
"db_name": "UniProt",
"db_id": "Q97IV1"
},
{
"db_name": "UniProt",
"db_id": "Q9CM00"
},
{
"db_name": "UniProt",
"db_id": "Q9HF78"
},
{
"db_name": "UniProt",
"db_id": "Q9HTY6"
},
{
"db_name": "UniProt",
"db_id": "Q9KUG5"
},
{
"db_name": "UniProt",
"db_id": "Q9NFN6"
},
{
"db_name": "UniProt",
"db_id": "Q9W3K5"
}
]
},
{
"id": "DS.d735.s1.e0",
"type": "compound",
"text": [
"homocysteine"
],
"offsets": [
[
163,
175
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "778"
}
]
},
{
"id": "DS.d735.s1.e1",
"type": "protein",
"text": [
"glutamate-cysteine ligase"
],
"offsets": [
[
201,
226
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O68838"
},
{
"db_name": "UniProt",
"db_id": "P0A6W9"
},
{
"db_name": "UniProt",
"db_id": "P0A6X0"
},
{
"db_name": "UniProt",
"db_id": "P32477"
},
{
"db_name": "UniProt",
"db_id": "P57485"
},
{
"db_name": "UniProt",
"db_id": "P58994"
},
{
"db_name": "UniProt",
"db_id": "P61379"
},
{
"db_name": "UniProt",
"db_id": "Q09768"
},
{
"db_name": "UniProt",
"db_id": "Q20117"
},
{
"db_name": "UniProt",
"db_id": "Q57KV3"
},
{
"db_name": "UniProt",
"db_id": "Q5E7F8"
},
{
"db_name": "UniProt",
"db_id": "Q5LYY5"
},
{
"db_name": "UniProt",
"db_id": "Q5M3J8"
},
{
"db_name": "UniProt",
"db_id": "Q5PF10"
},
{
"db_name": "UniProt",
"db_id": "Q65RX0"
},
{
"db_name": "UniProt",
"db_id": "Q66E64"
},
{
"db_name": "UniProt",
"db_id": "Q6ANW2"
},
{
"db_name": "UniProt",
"db_id": "Q6D1T4"
},
{
"db_name": "UniProt",
"db_id": "Q6LMV1"
},
{
"db_name": "UniProt",
"db_id": "Q71VZ1"
},
{
"db_name": "UniProt",
"db_id": "Q72RD4"
},
{
"db_name": "UniProt",
"db_id": "Q7MHS5"
},
{
"db_name": "UniProt",
"db_id": "Q7N7A4"
},
{
"db_name": "UniProt",
"db_id": "Q7W3F2"
},
{
"db_name": "UniProt",
"db_id": "Q7WES2"
},
{
"db_name": "UniProt",
"db_id": "Q82ZG8"
},
{
"db_name": "UniProt",
"db_id": "Q87LS2"
},
{
"db_name": "UniProt",
"db_id": "Q88AR1"
},
{
"db_name": "UniProt",
"db_id": "Q88R90"
},
{
"db_name": "UniProt",
"db_id": "Q88UW5"
},
{
"db_name": "UniProt",
"db_id": "Q89AD8"
},
{
"db_name": "UniProt",
"db_id": "Q8D2V5"
},
{
"db_name": "UniProt",
"db_id": "Q8DC38"
},
{
"db_name": "UniProt",
"db_id": "Q8DW15"
},
{
"db_name": "UniProt",
"db_id": "Q8DXM9"
},
{
"db_name": "UniProt",
"db_id": "Q8E399"
},
{
"db_name": "UniProt",
"db_id": "Q8EBF9"
},
{
"db_name": "UniProt",
"db_id": "Q8F4D5"
},
{
"db_name": "UniProt",
"db_id": "Q8X0X0"
},
{
"db_name": "UniProt",
"db_id": "Q8X900"
},
{
"db_name": "UniProt",
"db_id": "Q8XK30"
},
{
"db_name": "UniProt",
"db_id": "Q8Y3R3"
},
{
"db_name": "UniProt",
"db_id": "Q8Z4D6"
},
{
"db_name": "UniProt",
"db_id": "Q8ZBU2"
},
{
"db_name": "UniProt",
"db_id": "Q926X7"
},
{
"db_name": "UniProt",
"db_id": "Q97IV1"
},
{
"db_name": "UniProt",
"db_id": "Q9CM00"
},
{
"db_name": "UniProt",
"db_id": "Q9HF78"
},
{
"db_name": "UniProt",
"db_id": "Q9HTY6"
},
{
"db_name": "UniProt",
"db_id": "Q9KUG5"
},
{
"db_name": "UniProt",
"db_id": "Q9NFN6"
},
{
"db_name": "UniProt",
"db_id": "Q9W3K5"
}
]
},
{
"id": "DS.d735.s1.e2",
"type": "protein",
"text": [
"Gcl"
],
"offsets": [
[
228,
231
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0AEP7"
},
{
"db_name": "UniProt",
"db_id": "P0AEP8"
},
{
"db_name": "UniProt",
"db_id": "Q01820"
},
{
"db_name": "UniProt",
"db_id": "Q920G9"
}
]
},
{
"id": "DS.d735.s2.e0",
"type": "compound",
"text": [
"homocysteine"
],
"offsets": [
[
328,
340
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "778"
}
]
},
{
"id": "DS.d735.s2.e1",
"type": "compound",
"text": [
"glutathione"
],
"offsets": [
[
387,
398
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
},
{
"id": "DS.d735.s2.e2",
"type": "protein",
"text": [
"Gcl"
],
"offsets": [
[
430,
433
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0AEP7"
},
{
"db_name": "UniProt",
"db_id": "P0AEP8"
},
{
"db_name": "UniProt",
"db_id": "Q01820"
},
{
"db_name": "UniProt",
"db_id": "Q920G9"
}
]
},
{
"id": "DS.d735.s3.e0",
"type": "compound",
"text": [
"homocysteine"
],
"offsets": [
[
556,
568
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "778"
}
]
},
{
"id": "DS.d735.s3.e1",
"type": "protein",
"text": [
"luciferase"
],
"offsets": [
[
637,
647
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P08659"
},
{
"db_name": "UniProt",
"db_id": "P13129"
},
{
"db_name": "UniProt",
"db_id": "Q01158"
},
{
"db_name": "UniProt",
"db_id": "Q26304"
},
{
"db_name": "UniProt",
"db_id": "Q27757"
}
]
}
] | [] | [] | [
{
"id": "DS.d735.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d735.s0.e0",
"arg2_id": "DS.d735.s0.e1",
"normalized": []
},
{
"id": "DS.d735.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d735.s2.e0",
"arg2_id": "DS.d735.s2.e2",
"normalized": []
}
] |
DS.d736 | 18691757 | [
{
"id": "DS.d736.s0",
"type": "",
"text": [
"Ligand-induced Flt3-downregulation modulates cell death associated proteins and enhances chemosensitivity to idarubicin in THP-1 acute myeloid leukemia cells."
],
"offsets": [
[
0,
158
]
]
}
] | [
{
"id": "DS.d736.s0.e0",
"type": "protein",
"text": [
"Flt3"
],
"offsets": [
[
15,
19
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q00342"
}
]
},
{
"id": "DS.d736.s0.e1",
"type": "compound",
"text": [
"idarubicin"
],
"offsets": [
[
109,
119
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "42890"
}
]
}
] | [] | [] | [
{
"id": "DS.d736.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d736.s0.e1",
"arg2_id": "DS.d736.s0.e0",
"normalized": []
}
] |
DS.d737 | 18692155 | [
{
"id": "DS.d737.s0",
"type": "",
"text": [
"Only EGF activated ERK signaling and up-regulated early gene expression, while DHT triggered the expression of classical AR-responsive genes with the exception of the EGF-induced PSA transcript in A549 cells."
],
"offsets": [
[
0,
208
]
]
},
{
"id": "DS.d737.s1",
"type": "",
"text": [
"DHT and EGF up-regulated cyclinD1 (CD1) at both mRNA and protein levels in A549 cells, while in LNCaP cells each mitogen increased only CD1 protein expression."
],
"offsets": [
[
209,
368
]
]
}
] | [
{
"id": "DS.d737.s0.e0",
"type": "protein",
"text": [
"EGF"
],
"offsets": [
[
5,
8
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01132"
},
{
"db_name": "UniProt",
"db_id": "P01133"
},
{
"db_name": "UniProt",
"db_id": "P07522"
},
{
"db_name": "UniProt",
"db_id": "P26224"
},
{
"db_name": "UniProt",
"db_id": "Q00968"
},
{
"db_name": "UniProt",
"db_id": "Q95ND4"
},
{
"db_name": "UniProt",
"db_id": "Q9BEA0"
}
]
},
{
"id": "DS.d737.s0.e1",
"type": "protein",
"text": [
"ERK"
],
"offsets": [
[
19,
22
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P29323"
}
]
},
{
"id": "DS.d737.s0.e2",
"type": "compound",
"text": [
"DHT"
],
"offsets": [
[
79,
82
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "10635"
}
]
},
{
"id": "DS.d737.s0.e3",
"type": "protein",
"text": [
"EGF"
],
"offsets": [
[
167,
170
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01132"
},
{
"db_name": "UniProt",
"db_id": "P01133"
},
{
"db_name": "UniProt",
"db_id": "P07522"
},
{
"db_name": "UniProt",
"db_id": "P26224"
},
{
"db_name": "UniProt",
"db_id": "Q00968"
},
{
"db_name": "UniProt",
"db_id": "Q95ND4"
},
{
"db_name": "UniProt",
"db_id": "Q9BEA0"
}
]
},
{
"id": "DS.d737.s0.e4",
"type": "protein",
"text": [
"PSA"
],
"offsets": [
[
179,
182
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P07288"
},
{
"db_name": "UniProt",
"db_id": "P10658"
},
{
"db_name": "UniProt",
"db_id": "P33619"
},
{
"db_name": "UniProt",
"db_id": "P55786"
},
{
"db_name": "UniProt",
"db_id": "Q11011"
},
{
"db_name": "UniProt",
"db_id": "Q6DT45"
},
{
"db_name": "UniProt",
"db_id": "Q9Y617"
}
]
},
{
"id": "DS.d737.s1.e0",
"type": "compound",
"text": [
"DHT"
],
"offsets": [
[
209,
212
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "10635"
}
]
},
{
"id": "DS.d737.s1.e1",
"type": "protein",
"text": [
"EGF"
],
"offsets": [
[
217,
220
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01132"
},
{
"db_name": "UniProt",
"db_id": "P01133"
},
{
"db_name": "UniProt",
"db_id": "P07522"
},
{
"db_name": "UniProt",
"db_id": "P26224"
},
{
"db_name": "UniProt",
"db_id": "Q00968"
},
{
"db_name": "UniProt",
"db_id": "Q95ND4"
},
{
"db_name": "UniProt",
"db_id": "Q9BEA0"
}
]
},
{
"id": "DS.d737.s1.e2",
"type": "protein",
"text": [
"CD1"
],
"offsets": [
[
244,
247
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P23043"
}
]
},
{
"id": "DS.d737.s1.e3",
"type": "protein",
"text": [
"CD1"
],
"offsets": [
[
345,
348
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P23043"
}
]
}
] | [] | [] | [
{
"id": "DS.d737.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d737.s1.e0",
"arg2_id": "DS.d737.s1.e2",
"normalized": []
}
] |
DS.d738 | 18692592 | [
{
"id": "DS.d738.s0",
"type": "",
"text": [
"High glucose induced endothelial cell growth inhibition is associated with an increase in TGFbeta1 secretion and inhibition of Ras prenylation via suppression of the mevalonate pathway."
],
"offsets": [
[
0,
185
]
]
},
{
"id": "DS.d738.s1",
"type": "",
"text": [
"The influence of the prenylation status of Ras on the observed changes in endothelial cell growth under high glucose conditions has not previously been examined."
],
"offsets": [
[
186,
347
]
]
}
] | [
{
"id": "DS.d738.s0.e0",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
5,
12
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d738.s0.e1",
"type": "protein",
"text": [
"TGFbeta1"
],
"offsets": [
[
90,
98
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O19011"
},
{
"db_name": "UniProt",
"db_id": "O93449"
},
{
"db_name": "UniProt",
"db_id": "P01137"
},
{
"db_name": "UniProt",
"db_id": "P04202"
},
{
"db_name": "UniProt",
"db_id": "P07200"
},
{
"db_name": "UniProt",
"db_id": "P09531"
},
{
"db_name": "UniProt",
"db_id": "P09533"
},
{
"db_name": "UniProt",
"db_id": "P16176"
},
{
"db_name": "UniProt",
"db_id": "P17246"
},
{
"db_name": "UniProt",
"db_id": "P18341"
},
{
"db_name": "UniProt",
"db_id": "P50414"
},
{
"db_name": "UniProt",
"db_id": "P54831"
},
{
"db_name": "UniProt",
"db_id": "Q38HS2"
},
{
"db_name": "UniProt",
"db_id": "Q9PTQ2"
},
{
"db_name": "UniProt",
"db_id": "Q9Z1Y6"
}
]
},
{
"id": "DS.d738.s0.e2",
"type": "protein",
"text": [
"Ras"
],
"offsets": [
[
127,
130
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P03967"
},
{
"db_name": "UniProt",
"db_id": "P22126"
},
{
"db_name": "UniProt",
"db_id": "Q07152"
}
]
},
{
"id": "DS.d738.s1.e0",
"type": "protein",
"text": [
"Ras"
],
"offsets": [
[
229,
232
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P03967"
},
{
"db_name": "UniProt",
"db_id": "P22126"
},
{
"db_name": "UniProt",
"db_id": "Q07152"
}
]
},
{
"id": "DS.d738.s1.e1",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
295,
302
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
}
] | [] | [] | [
{
"id": "DS.d738.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d738.s0.e0",
"arg2_id": "DS.d738.s0.e1",
"normalized": []
},
{
"id": "DS.d738.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d738.s0.e0",
"arg2_id": "DS.d738.s0.e2",
"normalized": []
}
] |
DS.d739 | 18692599 | [
{
"id": "DS.d739.s0",
"type": "",
"text": [
"Calcineurin inhibitors (CsA, FK-506 and pimecrolimus) inhibited NO production and iNOS expression in a concentration-dependent manner, CsA being more potent than FK-506 and pimecrolimus."
],
"offsets": [
[
0,
186
]
]
},
{
"id": "DS.d739.s1",
"type": "",
"text": [
"In conclusion, the results suggest that calcineurin inhibitors cyclosporin A, tacrolimus (FK-506) and pimecrolimus inhibit iNOS expression and NO production in response to inflammatory stimuli by enhancing the decay of iNOS mRNA by a 3'UTR-dependent manner."
],
"offsets": [
[
187,
444
]
]
}
] | [
{
"id": "DS.d739.s0.e1",
"type": "compound",
"text": [
"FK-506"
],
"offsets": [
[
29,
35
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6436007"
}
]
},
{
"id": "DS.d739.s0.e2",
"type": "compound",
"text": [
"pimecrolimus"
],
"offsets": [
[
40,
52
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6447131"
},
{
"db_name": "PubChem",
"db_id": "6509979"
},
{
"db_name": "PubChem",
"db_id": "17753757"
},
{
"db_name": "PubChem",
"db_id": "24847863"
},
{
"db_name": "PubChem",
"db_id": "53394893"
},
{
"db_name": "PubChem",
"db_id": "53486290"
}
]
},
{
"id": "DS.d739.s0.e3",
"type": "protein",
"text": [
"iNOS"
],
"offsets": [
[
82,
86
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O19114"
},
{
"db_name": "UniProt",
"db_id": "O46660"
},
{
"db_name": "UniProt",
"db_id": "O54705"
},
{
"db_name": "UniProt",
"db_id": "O62699"
},
{
"db_name": "UniProt",
"db_id": "P29477"
},
{
"db_name": "UniProt",
"db_id": "P35228"
},
{
"db_name": "UniProt",
"db_id": "P79290"
},
{
"db_name": "UniProt",
"db_id": "Q06518"
},
{
"db_name": "UniProt",
"db_id": "Q27995"
},
{
"db_name": "UniProt",
"db_id": "Q28314"
},
{
"db_name": "UniProt",
"db_id": "Q90703"
},
{
"db_name": "UniProt",
"db_id": "Q92037"
},
{
"db_name": "UniProt",
"db_id": "Q92091"
}
]
},
{
"id": "DS.d739.s0.e4",
"type": "compound",
"text": [
"FK-506"
],
"offsets": [
[
162,
168
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6436007"
}
]
},
{
"id": "DS.d739.s0.e5",
"type": "compound",
"text": [
"pimecrolimus"
],
"offsets": [
[
173,
185
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6447131"
},
{
"db_name": "PubChem",
"db_id": "6509979"
},
{
"db_name": "PubChem",
"db_id": "17753757"
},
{
"db_name": "PubChem",
"db_id": "24847863"
},
{
"db_name": "PubChem",
"db_id": "53394893"
},
{
"db_name": "PubChem",
"db_id": "53486290"
}
]
},
{
"id": "DS.d739.s1.e1",
"type": "compound",
"text": [
"cyclosporin A"
],
"offsets": [
[
250,
263
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2909"
},
{
"db_name": "PubChem",
"db_id": "5280754"
},
{
"db_name": "PubChem",
"db_id": "5284373"
},
{
"db_name": "PubChem",
"db_id": "5458585"
},
{
"db_name": "PubChem",
"db_id": "5497195"
},
{
"db_name": "PubChem",
"db_id": "6435893"
},
{
"db_name": "PubChem",
"db_id": "24883466"
},
{
"db_name": "PubChem",
"db_id": "49867938"
}
]
},
{
"id": "DS.d739.s1.e2",
"type": "compound",
"text": [
"tacrolimus"
],
"offsets": [
[
265,
275
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5372"
},
{
"db_name": "PubChem",
"db_id": "445643"
},
{
"db_name": "PubChem",
"db_id": "445647"
},
{
"db_name": "PubChem",
"db_id": "6426916"
},
{
"db_name": "PubChem",
"db_id": "6436007"
},
{
"db_name": "PubChem",
"db_id": "6473866"
},
{
"db_name": "PubChem",
"db_id": "6536850"
},
{
"db_name": "PubChem",
"db_id": "9940643"
},
{
"db_name": "PubChem",
"db_id": "23581796"
},
{
"db_name": "PubChem",
"db_id": "54611630"
}
]
},
{
"id": "DS.d739.s1.e3",
"type": "compound",
"text": [
"FK-506"
],
"offsets": [
[
277,
283
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6436007"
}
]
},
{
"id": "DS.d739.s1.e4",
"type": "compound",
"text": [
"pimecrolimus"
],
"offsets": [
[
289,
301
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6447131"
},
{
"db_name": "PubChem",
"db_id": "6509979"
},
{
"db_name": "PubChem",
"db_id": "17753757"
},
{
"db_name": "PubChem",
"db_id": "24847863"
},
{
"db_name": "PubChem",
"db_id": "53394893"
},
{
"db_name": "PubChem",
"db_id": "53486290"
}
]
},
{
"id": "DS.d739.s1.e5",
"type": "protein",
"text": [
"iNOS"
],
"offsets": [
[
310,
314
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O19114"
},
{
"db_name": "UniProt",
"db_id": "O46660"
},
{
"db_name": "UniProt",
"db_id": "O54705"
},
{
"db_name": "UniProt",
"db_id": "O62699"
},
{
"db_name": "UniProt",
"db_id": "P29477"
},
{
"db_name": "UniProt",
"db_id": "P35228"
},
{
"db_name": "UniProt",
"db_id": "P79290"
},
{
"db_name": "UniProt",
"db_id": "Q06518"
},
{
"db_name": "UniProt",
"db_id": "Q27995"
},
{
"db_name": "UniProt",
"db_id": "Q28314"
},
{
"db_name": "UniProt",
"db_id": "Q90703"
},
{
"db_name": "UniProt",
"db_id": "Q92037"
},
{
"db_name": "UniProt",
"db_id": "Q92091"
}
]
},
{
"id": "DS.d739.s1.e6",
"type": "protein",
"text": [
"iNOS"
],
"offsets": [
[
406,
410
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O19114"
},
{
"db_name": "UniProt",
"db_id": "O46660"
},
{
"db_name": "UniProt",
"db_id": "O54705"
},
{
"db_name": "UniProt",
"db_id": "O62699"
},
{
"db_name": "UniProt",
"db_id": "P29477"
},
{
"db_name": "UniProt",
"db_id": "P35228"
},
{
"db_name": "UniProt",
"db_id": "P79290"
},
{
"db_name": "UniProt",
"db_id": "Q06518"
},
{
"db_name": "UniProt",
"db_id": "Q27995"
},
{
"db_name": "UniProt",
"db_id": "Q28314"
},
{
"db_name": "UniProt",
"db_id": "Q90703"
},
{
"db_name": "UniProt",
"db_id": "Q92037"
},
{
"db_name": "UniProt",
"db_id": "Q92091"
}
]
}
] | [] | [] | [
{
"id": "DS.d739.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d739.s0.e1",
"arg2_id": "DS.d739.s0.e3",
"normalized": []
},
{
"id": "DS.d739.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d739.s0.e2",
"arg2_id": "DS.d739.s0.e3",
"normalized": []
},
{
"id": "DS.d739.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d739.s1.e4",
"arg2_id": "DS.d739.s1.e5",
"normalized": []
},
{
"id": "DS.d739.s1.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d739.s1.e1",
"arg2_id": "DS.d739.s1.e5",
"normalized": []
},
{
"id": "DS.d739.s1.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d739.s1.e2",
"arg2_id": "DS.d739.s1.e5",
"normalized": []
},
{
"id": "DS.d739.s1.i7",
"type": "compound-protein-interaction",
"arg1_id": "DS.d739.s1.e3",
"arg2_id": "DS.d739.s1.e5",
"normalized": []
}
] |
DS.d740 | 18692849 | [
{
"id": "DS.d740.s0",
"type": "",
"text": [
"An increased activity of ATP-binding cassette transporter A1 (ABCA1) and ABCG5/G8 heterodimer has been proposed as a mechanism underlying the hypocholesterolaemic effect of phytosterols."
],
"offsets": [
[
0,
186
]
]
}
] | [
{
"id": "DS.d740.s0.e0",
"type": "protein",
"text": [
"ABCA1"
],
"offsets": [
[
62,
67
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O95477"
}
]
},
{
"id": "DS.d740.s0.e1",
"type": "protein",
"text": [
"ABCG5"
],
"offsets": [
[
73,
78
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q9H222"
}
]
},
{
"id": "DS.d740.s0.e2",
"type": "compound",
"text": [
"phytosterols"
],
"offsets": [
[
173,
185
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "12303662"
}
]
}
] | [] | [] | [
{
"id": "DS.d740.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d740.s0.e2",
"arg2_id": "DS.d740.s0.e0",
"normalized": []
},
{
"id": "DS.d740.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d740.s0.e2",
"arg2_id": "DS.d740.s0.e1",
"normalized": []
}
] |
DS.d741 | 18692896 | [
{
"id": "DS.d741.s0",
"type": "",
"text": [
"In sum, copper exposure lowered TOSC, a result that at least in part can be related to lowering of antioxidant enzymes like CAT."
],
"offsets": [
[
0,
128
]
]
}
] | [
{
"id": "DS.d741.s0.e0",
"type": "compound",
"text": [
"copper"
],
"offsets": [
[
8,
14
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "23978"
}
]
},
{
"id": "DS.d741.s0.e1",
"type": "protein",
"text": [
"CAT"
],
"offsets": [
[
124,
127
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62839"
},
{
"db_name": "UniProt",
"db_id": "O97492"
},
{
"db_name": "UniProt",
"db_id": "P00432"
},
{
"db_name": "UniProt",
"db_id": "P00485"
},
{
"db_name": "UniProt",
"db_id": "P00486"
},
{
"db_name": "UniProt",
"db_id": "P00487"
},
{
"db_name": "UniProt",
"db_id": "P04040"
},
{
"db_name": "UniProt",
"db_id": "P06135"
},
{
"db_name": "UniProt",
"db_id": "P07641"
},
{
"db_name": "UniProt",
"db_id": "P11504"
},
{
"db_name": "UniProt",
"db_id": "P20074"
},
{
"db_name": "UniProt",
"db_id": "P22782"
},
{
"db_name": "UniProt",
"db_id": "P25309"
},
{
"db_name": "UniProt",
"db_id": "P25819"
},
{
"db_name": "UniProt",
"db_id": "P26825"
},
{
"db_name": "UniProt",
"db_id": "P26826"
},
{
"db_name": "UniProt",
"db_id": "P32796"
},
{
"db_name": "UniProt",
"db_id": "P36882"
},
{
"db_name": "UniProt",
"db_id": "P36883"
},
{
"db_name": "UniProt",
"db_id": "P43155"
},
{
"db_name": "UniProt",
"db_id": "P47934"
},
{
"db_name": "UniProt",
"db_id": "P49417"
},
{
"db_name": "UniProt",
"db_id": "P52826"
},
{
"db_name": "UniProt",
"db_id": "P58777"
},
{
"db_name": "UniProt",
"db_id": "P62577"
},
{
"db_name": "UniProt",
"db_id": "P62578"
},
{
"db_name": "UniProt",
"db_id": "P62579"
},
{
"db_name": "UniProt",
"db_id": "P62580"
},
{
"db_name": "UniProt",
"db_id": "P90682"
},
{
"db_name": "UniProt",
"db_id": "Q00614"
},
{
"db_name": "UniProt",
"db_id": "Q02736"
},
{
"db_name": "UniProt",
"db_id": "Q03058"
},
{
"db_name": "UniProt",
"db_id": "Q5RF10"
},
{
"db_name": "UniProt",
"db_id": "Q64405"
},
{
"db_name": "UniProt",
"db_id": "Q704S8"
},
{
"db_name": "UniProt",
"db_id": "Q9M5L6"
},
{
"db_name": "UniProt",
"db_id": "Q9PWF7"
}
]
}
] | [] | [] | [
{
"id": "DS.d741.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d741.s0.e0",
"arg2_id": "DS.d741.s0.e1",
"normalized": []
}
] |
DS.d742 | 18693051 | [
{
"id": "DS.d742.s0",
"type": "",
"text": [
"Accumulation of glucose in PA was increased by insulin at 10nM and by IGF-I at 1 nM and 10nM."
],
"offsets": [
[
0,
93
]
]
}
] | [
{
"id": "DS.d742.s0.e0",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
16,
23
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d742.s0.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
47,
54
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d742.s0.e2",
"type": "protein",
"text": [
"IGF-I"
],
"offsets": [
[
70,
75
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05017"
},
{
"db_name": "UniProt",
"db_id": "P07455"
},
{
"db_name": "UniProt",
"db_id": "P08025"
},
{
"db_name": "UniProt",
"db_id": "P10763"
},
{
"db_name": "UniProt",
"db_id": "P16545"
},
{
"db_name": "UniProt",
"db_id": "P17085"
},
{
"db_name": "UniProt",
"db_id": "P17647"
},
{
"db_name": "UniProt",
"db_id": "P18254"
},
{
"db_name": "UniProt",
"db_id": "P33712"
},
{
"db_name": "UniProt",
"db_id": "P51457"
},
{
"db_name": "UniProt",
"db_id": "P51458"
},
{
"db_name": "UniProt",
"db_id": "P51462"
},
{
"db_name": "UniProt",
"db_id": "Q02815"
},
{
"db_name": "UniProt",
"db_id": "Q28933"
},
{
"db_name": "UniProt",
"db_id": "Q68LC0"
},
{
"db_name": "UniProt",
"db_id": "Q6GUL6"
},
{
"db_name": "UniProt",
"db_id": "Q6IVA5"
},
{
"db_name": "UniProt",
"db_id": "Q6JLX1"
},
{
"db_name": "UniProt",
"db_id": "Q95222"
}
]
}
] | [] | [] | [
{
"id": "DS.d742.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d742.s0.e0",
"arg2_id": "DS.d742.s0.e1",
"normalized": []
},
{
"id": "DS.d742.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d742.s0.e0",
"arg2_id": "DS.d742.s0.e2",
"normalized": []
}
] |
DS.d743 | 18693094 | [
{
"id": "DS.d743.s0",
"type": "",
"text": [
"Glucagon is important to this response because it increases glutamine uptake."
],
"offsets": [
[
0,
77
]
]
}
] | [
{
"id": "DS.d743.s0.e0",
"type": "protein",
"text": [
"Glucagon"
],
"offsets": [
[
0,
8
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12956"
},
{
"db_name": "UniProt",
"db_id": "O42143"
},
{
"db_name": "UniProt",
"db_id": "O42144"
},
{
"db_name": "UniProt",
"db_id": "P01272"
},
{
"db_name": "UniProt",
"db_id": "P01273"
},
{
"db_name": "UniProt",
"db_id": "P01274"
},
{
"db_name": "UniProt",
"db_id": "P01275"
},
{
"db_name": "UniProt",
"db_id": "P04093"
},
{
"db_name": "UniProt",
"db_id": "P05110"
},
{
"db_name": "UniProt",
"db_id": "P06883"
},
{
"db_name": "UniProt",
"db_id": "P07449"
},
{
"db_name": "UniProt",
"db_id": "P09566"
},
{
"db_name": "UniProt",
"db_id": "P09567"
},
{
"db_name": "UniProt",
"db_id": "P09682"
},
{
"db_name": "UniProt",
"db_id": "P09686"
},
{
"db_name": "UniProt",
"db_id": "P0C235"
},
{
"db_name": "UniProt",
"db_id": "P13189"
},
{
"db_name": "UniProt",
"db_id": "P15438"
},
{
"db_name": "UniProt",
"db_id": "P18108"
},
{
"db_name": "UniProt",
"db_id": "P22890"
},
{
"db_name": "UniProt",
"db_id": "P29794"
},
{
"db_name": "UniProt",
"db_id": "P31297"
},
{
"db_name": "UniProt",
"db_id": "P33528"
},
{
"db_name": "UniProt",
"db_id": "P55095"
},
{
"db_name": "UniProt",
"db_id": "P68259"
},
{
"db_name": "UniProt",
"db_id": "P68260"
},
{
"db_name": "UniProt",
"db_id": "P68273"
},
{
"db_name": "UniProt",
"db_id": "P68274"
},
{
"db_name": "UniProt",
"db_id": "P68275"
},
{
"db_name": "UniProt",
"db_id": "P68952"
},
{
"db_name": "UniProt",
"db_id": "P68953"
},
{
"db_name": "UniProt",
"db_id": "P68954"
},
{
"db_name": "UniProt",
"db_id": "P68955"
},
{
"db_name": "UniProt",
"db_id": "P68956"
},
{
"db_name": "UniProt",
"db_id": "P68957"
},
{
"db_name": "UniProt",
"db_id": "P79695"
},
{
"db_name": "UniProt",
"db_id": "P81880"
},
{
"db_name": "UniProt",
"db_id": "Q8MJ25"
},
{
"db_name": "UniProt",
"db_id": "Q9PRQ9"
}
]
},
{
"id": "DS.d743.s0.e1",
"type": "compound",
"text": [
"glutamine"
],
"offsets": [
[
60,
69
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "738"
},
{
"db_name": "PubChem",
"db_id": "5961"
}
]
}
] | [] | [] | [
{
"id": "DS.d743.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d743.s0.e1",
"arg2_id": "DS.d743.s0.e0",
"normalized": []
}
] |
DS.d744 | 18693095 | [
{
"id": "DS.d744.s0",
"type": "",
"text": [
"It was shown that PAR significantly increased serum ALT, AST, ALP, liver MDA levels and significantly decreased liver GSH-Px activity, when compared to the control group (Group 1)."
],
"offsets": [
[
0,
180
]
]
}
] | [
{
"id": "DS.d744.s0.e0",
"type": "protein",
"text": [
"AST"
],
"offsets": [
[
57,
60
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0AE37"
},
{
"db_name": "UniProt",
"db_id": "P0AE38"
},
{
"db_name": "UniProt",
"db_id": "P80357"
},
{
"db_name": "UniProt",
"db_id": "P80358"
},
{
"db_name": "UniProt",
"db_id": "Q0TH83"
},
{
"db_name": "UniProt",
"db_id": "Q1C8B0"
},
{
"db_name": "UniProt",
"db_id": "Q1RB46"
},
{
"db_name": "UniProt",
"db_id": "Q321N9"
},
{
"db_name": "UniProt",
"db_id": "Q32G89"
},
{
"db_name": "UniProt",
"db_id": "Q3Z294"
},
{
"db_name": "UniProt",
"db_id": "Q5PHB9"
},
{
"db_name": "UniProt",
"db_id": "Q66B20"
},
{
"db_name": "UniProt",
"db_id": "Q7N2G8"
},
{
"db_name": "UniProt",
"db_id": "Q83L52"
},
{
"db_name": "UniProt",
"db_id": "Q8FH00"
},
{
"db_name": "UniProt",
"db_id": "Q8Z6G0"
},
{
"db_name": "UniProt",
"db_id": "Q8ZPV1"
},
{
"db_name": "UniProt",
"db_id": "Q9NRA2"
},
{
"db_name": "UniProt",
"db_id": "Q9ZC67"
}
]
},
{
"id": "DS.d744.s0.e1",
"type": "protein",
"text": [
"ALP"
],
"offsets": [
[
62,
65
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P03973"
},
{
"db_name": "UniProt",
"db_id": "P12547"
},
{
"db_name": "UniProt",
"db_id": "P22298"
},
{
"db_name": "UniProt",
"db_id": "P28296"
},
{
"db_name": "UniProt",
"db_id": "P29118"
},
{
"db_name": "UniProt",
"db_id": "P35211"
},
{
"db_name": "UniProt",
"db_id": "P83610"
},
{
"db_name": "UniProt",
"db_id": "P97430"
},
{
"db_name": "UniProt",
"db_id": "Q03420"
},
{
"db_name": "UniProt",
"db_id": "Q53GG5"
},
{
"db_name": "UniProt",
"db_id": "Q9H0A0"
},
{
"db_name": "UniProt",
"db_id": "Q9PU47"
},
{
"db_name": "UniProt",
"db_id": "Q9Z1X0"
}
]
},
{
"id": "DS.d744.s0.e2",
"type": "compound",
"text": [
"GSH"
],
"offsets": [
[
118,
121
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
}
] | [] | [] | [] |
DS.d745 | 18693100 | [
{
"id": "DS.d745.s0",
"type": "",
"text": [
"Biological testing of the compound demonstrated a significant antidiabetic activity by reducing the elevated blood glucose levels and restoring the insulin levels in streptozotocin-induced diabetic rats."
],
"offsets": [
[
0,
203
]
]
}
] | [
{
"id": "DS.d745.s0.e0",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
115,
122
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d745.s0.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
148,
155
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d745.s0.e2",
"type": "compound",
"text": [
"streptozotocin"
],
"offsets": [
[
166,
180
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5300"
},
{
"db_name": "PubChem",
"db_id": "29327"
},
{
"db_name": "PubChem",
"db_id": "6420074"
},
{
"db_name": "PubChem",
"db_id": "6713972"
},
{
"db_name": "PubChem",
"db_id": "7067772"
},
{
"db_name": "PubChem",
"db_id": "45357367"
}
]
}
] | [] | [] | [] |
DS.d746 | 18693294 | [
{
"id": "DS.d746.s0",
"type": "",
"text": [
"The activity of guanylyl cyclase was determined by the amount of cGMP generated in responses to sodium nitroprusside (SNP) or ANP."
],
"offsets": [
[
0,
130
]
]
}
] | [
{
"id": "DS.d746.s0.e0",
"type": "protein",
"text": [
"cyclase"
],
"offsets": [
[
25,
32
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O94303"
},
{
"db_name": "UniProt",
"db_id": "P33734"
},
{
"db_name": "UniProt",
"db_id": "Q9P4P9"
},
{
"db_name": "UniProt",
"db_id": "Q9SZ30"
}
]
},
{
"id": "DS.d746.s0.e1",
"type": "compound",
"text": [
"cGMP"
],
"offsets": [
[
65,
69
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "24316"
}
]
}
] | [] | [] | [
{
"id": "DS.d746.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d746.s0.e1",
"arg2_id": "DS.d746.s0.e0",
"normalized": []
}
] |
DS.d747 | 18694296 | [
{
"id": "DS.d747.s0",
"type": "",
"text": [
"Both SAHA and MS-275 induced an arrest in the cell cycle along with the induction of apoptotic pathways as evidenced by flow cytometry, annexin assay, detection of activated caspase 9, and molecular analysis of Bax/Bcl-2 expression."
],
"offsets": [
[
0,
232
]
]
}
] | [
{
"id": "DS.d747.s0.e0",
"type": "compound",
"text": [
"SAHA"
],
"offsets": [
[
5,
9
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5311"
}
]
},
{
"id": "DS.d747.s0.e1",
"type": "compound",
"text": [
"MS-275"
],
"offsets": [
[
14,
20
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4261"
}
]
},
{
"id": "DS.d747.s0.e2",
"type": "protein",
"text": [
"Bax"
],
"offsets": [
[
211,
214
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P27297"
},
{
"db_name": "UniProt",
"db_id": "Q07813"
},
{
"db_name": "UniProt",
"db_id": "Q63690"
}
]
},
{
"id": "DS.d747.s0.e3",
"type": "protein",
"text": [
"Bcl-2"
],
"offsets": [
[
215,
220
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10417"
},
{
"db_name": "UniProt",
"db_id": "P49950"
}
]
}
] | [] | [] | [
{
"id": "DS.d747.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d747.s0.e1",
"arg2_id": "DS.d747.s0.e2",
"normalized": []
},
{
"id": "DS.d747.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d747.s0.e0",
"arg2_id": "DS.d747.s0.e2",
"normalized": []
},
{
"id": "DS.d747.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d747.s0.e1",
"arg2_id": "DS.d747.s0.e3",
"normalized": []
},
{
"id": "DS.d747.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d747.s0.e0",
"arg2_id": "DS.d747.s0.e3",
"normalized": []
}
] |
DS.d748 | 18694429 | [
{
"id": "DS.d748.s0",
"type": "",
"text": [
"Immunolocalization of androgen receptor in the boar epididymis: the effect of GnRH agonist deslorelin."
],
"offsets": [
[
0,
102
]
]
}
] | [
{
"id": "DS.d748.s0.e0",
"type": "protein",
"text": [
"androgen receptor"
],
"offsets": [
[
22,
39
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O97775"
},
{
"db_name": "UniProt",
"db_id": "O97776"
},
{
"db_name": "UniProt",
"db_id": "O97952"
},
{
"db_name": "UniProt",
"db_id": "O97960"
},
{
"db_name": "UniProt",
"db_id": "P10275"
},
{
"db_name": "UniProt",
"db_id": "P15207"
},
{
"db_name": "UniProt",
"db_id": "P19091"
},
{
"db_name": "UniProt",
"db_id": "P49699"
},
{
"db_name": "UniProt",
"db_id": "Q6QT55"
},
{
"db_name": "UniProt",
"db_id": "Q7T1K4"
},
{
"db_name": "UniProt",
"db_id": "Q8MIK0"
},
{
"db_name": "UniProt",
"db_id": "Q9GKL7"
},
{
"db_name": "UniProt",
"db_id": "Q9TT90"
}
]
},
{
"id": "DS.d748.s0.e1",
"type": "compound",
"text": [
"deslorelin"
],
"offsets": [
[
91,
101
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "25074999"
},
{
"db_name": "PubChem",
"db_id": "25077495"
},
{
"db_name": "PubChem",
"db_id": "25078016"
}
]
}
] | [] | [] | [] |
DS.d749 | 18694845 | [
{
"id": "DS.d749.s0",
"type": "",
"text": [
"E(2) increased the expression of caveolin-1 and caveolin-2 mRNA and proteins, but pre-treatment with ICI 182,780 (an estrogen receptor (ER) antagonist) inhibited E(2)-induced increase in caveolin-1 and caveolin-2 proteins expression."
],
"offsets": [
[
0,
233
]
]
},
{
"id": "DS.d749.s1",
"type": "",
"text": [
"Phospho-caveolin-1 was significantly blocked by ICI 182,780 or pyrazolopyrimidine 2 (PP2 ; a Src-kinase inhibitor)."
],
"offsets": [
[
234,
349
]
]
},
{
"id": "DS.d749.s2",
"type": "",
"text": [
"LY 294002 (a PI3K inhibitor) or PD 98059 (an ERK1/2 inhibitor) prevented E(2)-induced increase in caveolin-1 expression and the accompanying ((3)H)-thymidine incorporation."
],
"offsets": [
[
350,
522
]
]
},
{
"id": "DS.d749.s3",
"type": "",
"text": [
"Furthermore, inhibition of caveolin-1 expression using a caveolin-1 siRNA significantly attenuated E(2)-induced up-regulation of proto-oncogenes, cell cycle regulatory proteins, ((3)H)-thymidine incorporation, overall cell number, and percent of the cell population in S phase, while mediating a concomitant increase in the G0/G1 population."
],
"offsets": [
[
523,
864
]
]
}
] | [
{
"id": "DS.d749.s0.e0",
"type": "protein",
"text": [
"caveolin-1"
],
"offsets": [
[
33,
43
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P33724"
},
{
"db_name": "UniProt",
"db_id": "P35431"
},
{
"db_name": "UniProt",
"db_id": "P41350"
},
{
"db_name": "UniProt",
"db_id": "P49817"
},
{
"db_name": "UniProt",
"db_id": "P79132"
},
{
"db_name": "UniProt",
"db_id": "Q03135"
},
{
"db_name": "UniProt",
"db_id": "Q07DV9"
},
{
"db_name": "UniProt",
"db_id": "Q07DX1"
},
{
"db_name": "UniProt",
"db_id": "Q07DY2"
},
{
"db_name": "UniProt",
"db_id": "Q07DZ2"
},
{
"db_name": "UniProt",
"db_id": "Q07E02"
},
{
"db_name": "UniProt",
"db_id": "Q07E25"
},
{
"db_name": "UniProt",
"db_id": "Q07E38"
},
{
"db_name": "UniProt",
"db_id": "Q07E49"
},
{
"db_name": "UniProt",
"db_id": "Q09YH8"
},
{
"db_name": "UniProt",
"db_id": "Q09YK1"
},
{
"db_name": "UniProt",
"db_id": "Q09YN6"
},
{
"db_name": "UniProt",
"db_id": "Q108U7"
},
{
"db_name": "UniProt",
"db_id": "Q2IBA5"
},
{
"db_name": "UniProt",
"db_id": "Q2IBC1"
},
{
"db_name": "UniProt",
"db_id": "Q2IBD7"
},
{
"db_name": "UniProt",
"db_id": "Q2IBF0"
},
{
"db_name": "UniProt",
"db_id": "Q2IBG8"
},
{
"db_name": "UniProt",
"db_id": "Q2QL79"
},
{
"db_name": "UniProt",
"db_id": "Q2QL90"
},
{
"db_name": "UniProt",
"db_id": "Q2QLB0"
},
{
"db_name": "UniProt",
"db_id": "Q2QLC1"
},
{
"db_name": "UniProt",
"db_id": "Q2QLF2"
},
{
"db_name": "UniProt",
"db_id": "Q2QLG6"
},
{
"db_name": "UniProt",
"db_id": "Q2QLH7"
},
{
"db_name": "UniProt",
"db_id": "Q6B3Y2"
},
{
"db_name": "UniProt",
"db_id": "Q6RVA9"
},
{
"db_name": "UniProt",
"db_id": "Q94051"
},
{
"db_name": "UniProt",
"db_id": "Q9YGM8"
}
]
},
{
"id": "DS.d749.s0.e1",
"type": "protein",
"text": [
"caveolin-2"
],
"offsets": [
[
48,
58
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O46550"
},
{
"db_name": "UniProt",
"db_id": "P51636"
},
{
"db_name": "UniProt",
"db_id": "Q07DW0"
},
{
"db_name": "UniProt",
"db_id": "Q07DX2"
},
{
"db_name": "UniProt",
"db_id": "Q07DZ3"
},
{
"db_name": "UniProt",
"db_id": "Q07E26"
},
{
"db_name": "UniProt",
"db_id": "Q07E39"
},
{
"db_name": "UniProt",
"db_id": "Q07E50"
},
{
"db_name": "UniProt",
"db_id": "Q09YH9"
},
{
"db_name": "UniProt",
"db_id": "Q09YJ1"
},
{
"db_name": "UniProt",
"db_id": "Q09YK2"
},
{
"db_name": "UniProt",
"db_id": "Q09YL4"
},
{
"db_name": "UniProt",
"db_id": "Q09YN7"
},
{
"db_name": "UniProt",
"db_id": "Q108U8"
},
{
"db_name": "UniProt",
"db_id": "Q18879"
},
{
"db_name": "UniProt",
"db_id": "Q2IBA4"
},
{
"db_name": "UniProt",
"db_id": "Q2IBC2"
},
{
"db_name": "UniProt",
"db_id": "Q2IBD6"
},
{
"db_name": "UniProt",
"db_id": "Q2IBF3"
},
{
"db_name": "UniProt",
"db_id": "Q2IBG9"
},
{
"db_name": "UniProt",
"db_id": "Q2QL80"
},
{
"db_name": "UniProt",
"db_id": "Q2QL91"
},
{
"db_name": "UniProt",
"db_id": "Q2QLB1"
},
{
"db_name": "UniProt",
"db_id": "Q2QLC2"
},
{
"db_name": "UniProt",
"db_id": "Q2QLD3"
},
{
"db_name": "UniProt",
"db_id": "Q2QLE2"
},
{
"db_name": "UniProt",
"db_id": "Q2QLF3"
},
{
"db_name": "UniProt",
"db_id": "Q2QLG7"
},
{
"db_name": "UniProt",
"db_id": "Q2QLH8"
},
{
"db_name": "UniProt",
"db_id": "Q66WT7"
},
{
"db_name": "UniProt",
"db_id": "Q9WVC3"
},
{
"db_name": "UniProt",
"db_id": "Q9YGM9"
}
]
},
{
"id": "DS.d749.s0.e2",
"type": "compound",
"text": [
"ICI 182,780"
],
"offsets": [
[
101,
112
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "104741"
}
]
},
{
"id": "DS.d749.s0.e3",
"type": "protein",
"text": [
"caveolin-1"
],
"offsets": [
[
187,
197
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P33724"
},
{
"db_name": "UniProt",
"db_id": "P35431"
},
{
"db_name": "UniProt",
"db_id": "P41350"
},
{
"db_name": "UniProt",
"db_id": "P49817"
},
{
"db_name": "UniProt",
"db_id": "P79132"
},
{
"db_name": "UniProt",
"db_id": "Q03135"
},
{
"db_name": "UniProt",
"db_id": "Q07DV9"
},
{
"db_name": "UniProt",
"db_id": "Q07DX1"
},
{
"db_name": "UniProt",
"db_id": "Q07DY2"
},
{
"db_name": "UniProt",
"db_id": "Q07DZ2"
},
{
"db_name": "UniProt",
"db_id": "Q07E02"
},
{
"db_name": "UniProt",
"db_id": "Q07E25"
},
{
"db_name": "UniProt",
"db_id": "Q07E38"
},
{
"db_name": "UniProt",
"db_id": "Q07E49"
},
{
"db_name": "UniProt",
"db_id": "Q09YH8"
},
{
"db_name": "UniProt",
"db_id": "Q09YK1"
},
{
"db_name": "UniProt",
"db_id": "Q09YN6"
},
{
"db_name": "UniProt",
"db_id": "Q108U7"
},
{
"db_name": "UniProt",
"db_id": "Q2IBA5"
},
{
"db_name": "UniProt",
"db_id": "Q2IBC1"
},
{
"db_name": "UniProt",
"db_id": "Q2IBD7"
},
{
"db_name": "UniProt",
"db_id": "Q2IBF0"
},
{
"db_name": "UniProt",
"db_id": "Q2IBG8"
},
{
"db_name": "UniProt",
"db_id": "Q2QL79"
},
{
"db_name": "UniProt",
"db_id": "Q2QL90"
},
{
"db_name": "UniProt",
"db_id": "Q2QLB0"
},
{
"db_name": "UniProt",
"db_id": "Q2QLC1"
},
{
"db_name": "UniProt",
"db_id": "Q2QLF2"
},
{
"db_name": "UniProt",
"db_id": "Q2QLG6"
},
{
"db_name": "UniProt",
"db_id": "Q2QLH7"
},
{
"db_name": "UniProt",
"db_id": "Q6B3Y2"
},
{
"db_name": "UniProt",
"db_id": "Q6RVA9"
},
{
"db_name": "UniProt",
"db_id": "Q94051"
},
{
"db_name": "UniProt",
"db_id": "Q9YGM8"
}
]
},
{
"id": "DS.d749.s0.e4",
"type": "protein",
"text": [
"caveolin-2"
],
"offsets": [
[
202,
212
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O46550"
},
{
"db_name": "UniProt",
"db_id": "P51636"
},
{
"db_name": "UniProt",
"db_id": "Q07DW0"
},
{
"db_name": "UniProt",
"db_id": "Q07DX2"
},
{
"db_name": "UniProt",
"db_id": "Q07DZ3"
},
{
"db_name": "UniProt",
"db_id": "Q07E26"
},
{
"db_name": "UniProt",
"db_id": "Q07E39"
},
{
"db_name": "UniProt",
"db_id": "Q07E50"
},
{
"db_name": "UniProt",
"db_id": "Q09YH9"
},
{
"db_name": "UniProt",
"db_id": "Q09YJ1"
},
{
"db_name": "UniProt",
"db_id": "Q09YK2"
},
{
"db_name": "UniProt",
"db_id": "Q09YL4"
},
{
"db_name": "UniProt",
"db_id": "Q09YN7"
},
{
"db_name": "UniProt",
"db_id": "Q108U8"
},
{
"db_name": "UniProt",
"db_id": "Q18879"
},
{
"db_name": "UniProt",
"db_id": "Q2IBA4"
},
{
"db_name": "UniProt",
"db_id": "Q2IBC2"
},
{
"db_name": "UniProt",
"db_id": "Q2IBD6"
},
{
"db_name": "UniProt",
"db_id": "Q2IBF3"
},
{
"db_name": "UniProt",
"db_id": "Q2IBG9"
},
{
"db_name": "UniProt",
"db_id": "Q2QL80"
},
{
"db_name": "UniProt",
"db_id": "Q2QL91"
},
{
"db_name": "UniProt",
"db_id": "Q2QLB1"
},
{
"db_name": "UniProt",
"db_id": "Q2QLC2"
},
{
"db_name": "UniProt",
"db_id": "Q2QLD3"
},
{
"db_name": "UniProt",
"db_id": "Q2QLE2"
},
{
"db_name": "UniProt",
"db_id": "Q2QLF3"
},
{
"db_name": "UniProt",
"db_id": "Q2QLG7"
},
{
"db_name": "UniProt",
"db_id": "Q2QLH8"
},
{
"db_name": "UniProt",
"db_id": "Q66WT7"
},
{
"db_name": "UniProt",
"db_id": "Q9WVC3"
},
{
"db_name": "UniProt",
"db_id": "Q9YGM9"
}
]
},
{
"id": "DS.d749.s1.e0",
"type": "protein",
"text": [
"caveolin-1"
],
"offsets": [
[
242,
252
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P33724"
},
{
"db_name": "UniProt",
"db_id": "P35431"
},
{
"db_name": "UniProt",
"db_id": "P41350"
},
{
"db_name": "UniProt",
"db_id": "P49817"
},
{
"db_name": "UniProt",
"db_id": "P79132"
},
{
"db_name": "UniProt",
"db_id": "Q03135"
},
{
"db_name": "UniProt",
"db_id": "Q07DV9"
},
{
"db_name": "UniProt",
"db_id": "Q07DX1"
},
{
"db_name": "UniProt",
"db_id": "Q07DY2"
},
{
"db_name": "UniProt",
"db_id": "Q07DZ2"
},
{
"db_name": "UniProt",
"db_id": "Q07E02"
},
{
"db_name": "UniProt",
"db_id": "Q07E25"
},
{
"db_name": "UniProt",
"db_id": "Q07E38"
},
{
"db_name": "UniProt",
"db_id": "Q07E49"
},
{
"db_name": "UniProt",
"db_id": "Q09YH8"
},
{
"db_name": "UniProt",
"db_id": "Q09YK1"
},
{
"db_name": "UniProt",
"db_id": "Q09YN6"
},
{
"db_name": "UniProt",
"db_id": "Q108U7"
},
{
"db_name": "UniProt",
"db_id": "Q2IBA5"
},
{
"db_name": "UniProt",
"db_id": "Q2IBC1"
},
{
"db_name": "UniProt",
"db_id": "Q2IBD7"
},
{
"db_name": "UniProt",
"db_id": "Q2IBF0"
},
{
"db_name": "UniProt",
"db_id": "Q2IBG8"
},
{
"db_name": "UniProt",
"db_id": "Q2QL79"
},
{
"db_name": "UniProt",
"db_id": "Q2QL90"
},
{
"db_name": "UniProt",
"db_id": "Q2QLB0"
},
{
"db_name": "UniProt",
"db_id": "Q2QLC1"
},
{
"db_name": "UniProt",
"db_id": "Q2QLF2"
},
{
"db_name": "UniProt",
"db_id": "Q2QLG6"
},
{
"db_name": "UniProt",
"db_id": "Q2QLH7"
},
{
"db_name": "UniProt",
"db_id": "Q6B3Y2"
},
{
"db_name": "UniProt",
"db_id": "Q6RVA9"
},
{
"db_name": "UniProt",
"db_id": "Q94051"
},
{
"db_name": "UniProt",
"db_id": "Q9YGM8"
}
]
},
{
"id": "DS.d749.s1.e1",
"type": "compound",
"text": [
"ICI 182,780"
],
"offsets": [
[
282,
293
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "104741"
}
]
},
{
"id": "DS.d749.s1.e2",
"type": "compound",
"text": [
"pyrazolopyrimidine"
],
"offsets": [
[
297,
315
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "15077741"
},
{
"db_name": "PubChem",
"db_id": "21083976"
}
]
},
{
"id": "DS.d749.s2.e0",
"type": "compound",
"text": [
"LY 294002"
],
"offsets": [
[
350,
359
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3973"
}
]
},
{
"id": "DS.d749.s2.e1",
"type": "compound",
"text": [
"PD 98059"
],
"offsets": [
[
382,
390
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4713"
}
]
},
{
"id": "DS.d749.s2.e2",
"type": "protein",
"text": [
"caveolin-1"
],
"offsets": [
[
448,
458
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P33724"
},
{
"db_name": "UniProt",
"db_id": "P35431"
},
{
"db_name": "UniProt",
"db_id": "P41350"
},
{
"db_name": "UniProt",
"db_id": "P49817"
},
{
"db_name": "UniProt",
"db_id": "P79132"
},
{
"db_name": "UniProt",
"db_id": "Q03135"
},
{
"db_name": "UniProt",
"db_id": "Q07DV9"
},
{
"db_name": "UniProt",
"db_id": "Q07DX1"
},
{
"db_name": "UniProt",
"db_id": "Q07DY2"
},
{
"db_name": "UniProt",
"db_id": "Q07DZ2"
},
{
"db_name": "UniProt",
"db_id": "Q07E02"
},
{
"db_name": "UniProt",
"db_id": "Q07E25"
},
{
"db_name": "UniProt",
"db_id": "Q07E38"
},
{
"db_name": "UniProt",
"db_id": "Q07E49"
},
{
"db_name": "UniProt",
"db_id": "Q09YH8"
},
{
"db_name": "UniProt",
"db_id": "Q09YK1"
},
{
"db_name": "UniProt",
"db_id": "Q09YN6"
},
{
"db_name": "UniProt",
"db_id": "Q108U7"
},
{
"db_name": "UniProt",
"db_id": "Q2IBA5"
},
{
"db_name": "UniProt",
"db_id": "Q2IBC1"
},
{
"db_name": "UniProt",
"db_id": "Q2IBD7"
},
{
"db_name": "UniProt",
"db_id": "Q2IBF0"
},
{
"db_name": "UniProt",
"db_id": "Q2IBG8"
},
{
"db_name": "UniProt",
"db_id": "Q2QL79"
},
{
"db_name": "UniProt",
"db_id": "Q2QL90"
},
{
"db_name": "UniProt",
"db_id": "Q2QLB0"
},
{
"db_name": "UniProt",
"db_id": "Q2QLC1"
},
{
"db_name": "UniProt",
"db_id": "Q2QLF2"
},
{
"db_name": "UniProt",
"db_id": "Q2QLG6"
},
{
"db_name": "UniProt",
"db_id": "Q2QLH7"
},
{
"db_name": "UniProt",
"db_id": "Q6B3Y2"
},
{
"db_name": "UniProt",
"db_id": "Q6RVA9"
},
{
"db_name": "UniProt",
"db_id": "Q94051"
},
{
"db_name": "UniProt",
"db_id": "Q9YGM8"
}
]
},
{
"id": "DS.d749.s2.e3",
"type": "compound",
"text": [
"thymidine"
],
"offsets": [
[
498,
507
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5789"
}
]
},
{
"id": "DS.d749.s3.e0",
"type": "protein",
"text": [
"cell cycle regulatory proteins"
],
"offsets": [
[
669,
699
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P18754"
},
{
"db_name": "UniProt",
"db_id": "Q18211"
}
]
},
{
"id": "DS.d749.s3.e1",
"type": "compound",
"text": [
"thymidine"
],
"offsets": [
[
708,
717
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5789"
}
]
}
] | [] | [] | [
{
"id": "DS.d749.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d749.s0.e2",
"arg2_id": "DS.d749.s0.e0",
"normalized": []
},
{
"id": "DS.d749.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d749.s0.e2",
"arg2_id": "DS.d749.s0.e1",
"normalized": []
},
{
"id": "DS.d749.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d749.s1.e1",
"arg2_id": "DS.d749.s1.e0",
"normalized": []
},
{
"id": "DS.d749.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d749.s1.e2",
"arg2_id": "DS.d749.s1.e0",
"normalized": []
},
{
"id": "DS.d749.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d749.s2.e3",
"arg2_id": "DS.d749.s2.e2",
"normalized": []
},
{
"id": "DS.d749.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d749.s2.e1",
"arg2_id": "DS.d749.s2.e2",
"normalized": []
},
{
"id": "DS.d749.s2.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d749.s2.e0",
"arg2_id": "DS.d749.s2.e2",
"normalized": []
}
] |
DS.d750 | 18694847 | [
{
"id": "DS.d750.s0",
"type": "",
"text": [
"Almost all Akt kinase that translocates to the nucleus shows a marked phosphorylation on serine 473."
],
"offsets": [
[
0,
100
]
]
}
] | [
{
"id": "DS.d750.s0.e0",
"type": "protein",
"text": [
"Akt"
],
"offsets": [
[
11,
14
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P31750"
},
{
"db_name": "UniProt",
"db_id": "Q8INB9"
}
]
},
{
"id": "DS.d750.s0.e1",
"type": "compound",
"text": [
"serine"
],
"offsets": [
[
89,
95
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5951"
}
]
}
] | [] | [] | [
{
"id": "DS.d750.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d750.s0.e1",
"arg2_id": "DS.d750.s0.e0",
"normalized": []
}
] |
DS.d751 | 18695846 | [
{
"id": "DS.d751.s0",
"type": "",
"text": [
"During the early response in AR, histamine has been found to be the most abundant mediator and it is associated with many symptoms of this disease mediated through the histamine H1 receptor."
],
"offsets": [
[
0,
190
]
]
}
] | [
{
"id": "DS.d751.s0.e0",
"type": "compound",
"text": [
"histamine"
],
"offsets": [
[
33,
42
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "774"
}
]
},
{
"id": "DS.d751.s0.e1",
"type": "protein",
"text": [
"histamine H1 receptor"
],
"offsets": [
[
168,
189
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P30546"
},
{
"db_name": "UniProt",
"db_id": "P31389"
},
{
"db_name": "UniProt",
"db_id": "P31390"
},
{
"db_name": "UniProt",
"db_id": "P35367"
},
{
"db_name": "UniProt",
"db_id": "P70174"
},
{
"db_name": "UniProt",
"db_id": "Q9N2B0"
},
{
"db_name": "UniProt",
"db_id": "Q9N2B1"
},
{
"db_name": "UniProt",
"db_id": "Q9N2B2"
}
]
}
] | [] | [] | [
{
"id": "DS.d751.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d751.s0.e0",
"arg2_id": "DS.d751.s0.e1",
"normalized": []
}
] |
DS.d752 | 18695937 | [
{
"id": "DS.d752.s0",
"type": "",
"text": [
"During the incubation of L-phenylalanine with para-hydroquinones using laccase as biocatalyst, one or two main products were formed."
],
"offsets": [
[
0,
132
]
]
}
] | [
{
"id": "DS.d752.s0.e0",
"type": "compound",
"text": [
"L-phenylalanine"
],
"offsets": [
[
25,
40
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6140"
}
]
},
{
"id": "DS.d752.s0.e1",
"type": "protein",
"text": [
"laccase"
],
"offsets": [
[
71,
78
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q12570"
}
]
}
] | [] | [] | [
{
"id": "DS.d752.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d752.s0.e0",
"arg2_id": "DS.d752.s0.e1",
"normalized": []
}
] |
DS.d753 | 18696104 | [
{
"id": "DS.d753.s0",
"type": "",
"text": [
"The effect on activation voltage but not that on amplitude was absent when expressing a cAMP-insensitive mutant (HCN2R/E), while a C-terminal truncated form of HCN2 (HCN2DeltaCx) exhibited only the voltage dependent but not the amplitude effect of erbstatin."
],
"offsets": [
[
0,
258
]
]
},
{
"id": "DS.d753.s1",
"type": "",
"text": [
"Thus, the action of erbstatin on the activation relation and current amplitude are distinct and separable in newborn myocytes, and the effect on activation voltage depends on the cAMP status of HCN2 channels."
],
"offsets": [
[
259,
467
]
]
},
{
"id": "DS.d753.s2",
"type": "",
"text": [
"In contrast to newborn myocytes, erbstatin had no effect on HCN2 under control conditions in adult myocytes but induced a negative shift with no change in amplitude when saturated cAMP was added to the pipette solution."
],
"offsets": [
[
468,
687
]
]
}
] | [
{
"id": "DS.d753.s0.e0",
"type": "protein",
"text": [
"HCN2"
],
"offsets": [
[
113,
117
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q9UL51"
}
]
},
{
"id": "DS.d753.s0.e1",
"type": "compound",
"text": [
"erbstatin"
],
"offsets": [
[
248,
257
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5328552"
}
]
},
{
"id": "DS.d753.s1.e0",
"type": "compound",
"text": [
"erbstatin"
],
"offsets": [
[
279,
288
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5328552"
}
]
},
{
"id": "DS.d753.s1.e1",
"type": "compound",
"text": [
"cAMP"
],
"offsets": [
[
438,
442
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6076"
}
]
},
{
"id": "DS.d753.s1.e2",
"type": "protein",
"text": [
"HCN2"
],
"offsets": [
[
453,
457
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q9UL51"
}
]
},
{
"id": "DS.d753.s2.e0",
"type": "compound",
"text": [
"erbstatin"
],
"offsets": [
[
501,
510
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5328552"
}
]
},
{
"id": "DS.d753.s2.e1",
"type": "protein",
"text": [
"HCN2"
],
"offsets": [
[
528,
532
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q9UL51"
}
]
},
{
"id": "DS.d753.s2.e2",
"type": "compound",
"text": [
"cAMP"
],
"offsets": [
[
648,
652
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6076"
}
]
}
] | [] | [] | [
{
"id": "DS.d753.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d753.s0.e1",
"arg2_id": "DS.d753.s0.e0",
"normalized": []
},
{
"id": "DS.d753.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d753.s1.e1",
"arg2_id": "DS.d753.s1.e2",
"normalized": []
},
{
"id": "DS.d753.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d753.s1.e0",
"arg2_id": "DS.d753.s1.e2",
"normalized": []
}
] |
DS.d754 | 18696216 | [
{
"id": "DS.d754.s0",
"type": "",
"text": [
"Arginine-specific ADP-ribosyltransferase (Art) catalyzes the mono-ADP-ribosylation, in which it transfers a single ADP-ribose moiety of NAD to the arginine residue(s) of target proteins, and may regulate the function of the proteins or peptides in cellular processes."
],
"offsets": [
[
0,
267
]
]
}
] | [
{
"id": "DS.d754.s0.e0",
"type": "compound",
"text": [
"Arginine"
],
"offsets": [
[
0,
8
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "232"
},
{
"db_name": "PubChem",
"db_id": "4367"
},
{
"db_name": "PubChem",
"db_id": "6322"
}
]
},
{
"id": "DS.d754.s0.e1",
"type": "protein",
"text": [
"ADP-ribosyltransferase"
],
"offsets": [
[
18,
40
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P14299"
}
]
},
{
"id": "DS.d754.s0.e2",
"type": "compound",
"text": [
"NAD"
],
"offsets": [
[
136,
139
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5893"
}
]
},
{
"id": "DS.d754.s0.e3",
"type": "compound",
"text": [
"arginine"
],
"offsets": [
[
147,
155
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "232"
},
{
"db_name": "PubChem",
"db_id": "4367"
},
{
"db_name": "PubChem",
"db_id": "6322"
}
]
}
] | [] | [] | [
{
"id": "DS.d754.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d754.s0.e3",
"arg2_id": "DS.d754.s0.e1",
"normalized": []
},
{
"id": "DS.d754.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d754.s0.e0",
"arg2_id": "DS.d754.s0.e1",
"normalized": []
},
{
"id": "DS.d754.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d754.s0.e2",
"arg2_id": "DS.d754.s0.e1",
"normalized": []
}
] |
DS.d756 | 18696261 | [
{
"id": "DS.d756.s0",
"type": "",
"text": [
"A D-amino acid oxidase gene (dao) was ligated with the P(Hase) and cloned into pGEMKT to constitutively express protein of DAAO without the use of any inducer such as isopropyl beta-D-1-thiogalactopyranoside which is poisonous to the cells and environment."
],
"offsets": [
[
0,
256
]
]
}
] | [
{
"id": "DS.d756.s0.e0",
"type": "protein",
"text": [
"dao"
],
"offsets": [
[
29,
32
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35078"
},
{
"db_name": "UniProt",
"db_id": "P18894"
}
]
},
{
"id": "DS.d756.s0.e1",
"type": "protein",
"text": [
"DAAO"
],
"offsets": [
[
123,
127
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O01739"
},
{
"db_name": "UniProt",
"db_id": "O35078"
},
{
"db_name": "UniProt",
"db_id": "P00371"
},
{
"db_name": "UniProt",
"db_id": "P14920"
},
{
"db_name": "UniProt",
"db_id": "P18894"
},
{
"db_name": "UniProt",
"db_id": "P22942"
},
{
"db_name": "UniProt",
"db_id": "P24552"
},
{
"db_name": "UniProt",
"db_id": "P80324"
},
{
"db_name": "UniProt",
"db_id": "Q19564"
},
{
"db_name": "UniProt",
"db_id": "Q99042"
},
{
"db_name": "UniProt",
"db_id": "Q9Z1M5"
},
{
"db_name": "UniProt",
"db_id": "Q9Z302"
}
]
},
{
"id": "DS.d756.s0.e2",
"type": "compound",
"text": [
"isopropyl beta-D-1-thiogalactopyranoside"
],
"offsets": [
[
167,
207
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "656894"
}
]
}
] | [] | [] | [
{
"id": "DS.d756.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d756.s0.e2",
"arg2_id": "DS.d756.s0.e1",
"normalized": []
},
{
"id": "DS.d756.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d756.s0.e2",
"arg2_id": "DS.d756.s0.e0",
"normalized": []
}
] |
DS.d757 | 18698091 | [
{
"id": "DS.d757.s0",
"type": "",
"text": [
"In response to a cholesterol-containing atherogenic diet, C57BL/6J mice significantly increased expression of UCP2 in the aorta, while mice lacking UCP2, in the absence of any other genetic modification, displayed significant endothelial dysfunction following the atherogenic diet."
],
"offsets": [
[
0,
281
]
]
},
{
"id": "DS.d757.s1",
"type": "",
"text": [
"These data establish that in the vasculature UCP2 functions as an adaptive antioxidant defense to protect against the development of atherosclerosis in response to a fat and cholesterol diet."
],
"offsets": [
[
282,
473
]
]
}
] | [
{
"id": "DS.d757.s0.e0",
"type": "compound",
"text": [
"cholesterol"
],
"offsets": [
[
17,
28
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "304"
},
{
"db_name": "PubChem",
"db_id": "5997"
},
{
"db_name": "PubChem",
"db_id": "6432564"
},
{
"db_name": "PubChem",
"db_id": "11025495"
}
]
},
{
"id": "DS.d757.s0.e1",
"type": "protein",
"text": [
"UCP2"
],
"offsets": [
[
110,
114
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O97562"
},
{
"db_name": "UniProt",
"db_id": "P55851"
},
{
"db_name": "UniProt",
"db_id": "Q9N2J1"
},
{
"db_name": "UniProt",
"db_id": "Q9W725"
}
]
},
{
"id": "DS.d757.s0.e2",
"type": "protein",
"text": [
"UCP2"
],
"offsets": [
[
148,
152
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O97562"
},
{
"db_name": "UniProt",
"db_id": "P55851"
},
{
"db_name": "UniProt",
"db_id": "Q9N2J1"
},
{
"db_name": "UniProt",
"db_id": "Q9W725"
}
]
},
{
"id": "DS.d757.s1.e0",
"type": "protein",
"text": [
"UCP2"
],
"offsets": [
[
327,
331
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O97562"
},
{
"db_name": "UniProt",
"db_id": "P55851"
},
{
"db_name": "UniProt",
"db_id": "Q9N2J1"
},
{
"db_name": "UniProt",
"db_id": "Q9W725"
}
]
},
{
"id": "DS.d757.s1.e1",
"type": "compound",
"text": [
"cholesterol"
],
"offsets": [
[
456,
467
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "304"
},
{
"db_name": "PubChem",
"db_id": "5997"
},
{
"db_name": "PubChem",
"db_id": "6432564"
},
{
"db_name": "PubChem",
"db_id": "11025495"
}
]
}
] | [] | [] | [
{
"id": "DS.d757.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d757.s0.e0",
"arg2_id": "DS.d757.s0.e1",
"normalized": []
},
{
"id": "DS.d757.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d757.s1.e1",
"arg2_id": "DS.d757.s1.e0",
"normalized": []
}
] |
DS.d758 | 18698130 | [
{
"id": "DS.d758.s0",
"type": "",
"text": [
"To confirm that mouse DMP1-PG possesses a single GAG chain attached to Ser (89), we substituted Ser (89) by Gly (89)."
],
"offsets": [
[
0,
117
]
]
}
] | [
{
"id": "DS.d758.s0.e0",
"type": "protein",
"text": [
"DMP1"
],
"offsets": [
[
22,
26
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q13316"
},
{
"db_name": "UniProt",
"db_id": "Q95120"
}
]
},
{
"id": "DS.d758.s0.e1",
"type": "compound",
"text": [
"Gly"
],
"offsets": [
[
108,
111
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "750"
},
{
"db_name": "PubChem",
"db_id": "5460845"
}
]
}
] | [] | [] | [
{
"id": "DS.d758.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d758.s0.e1",
"arg2_id": "DS.d758.s0.e0",
"normalized": []
}
] |
DS.d759 | 18698132 | [
{
"id": "DS.d759.s0",
"type": "",
"text": [
"PC-1 is the primary generator of pyrophosphate in osteoblastic cells; therefore, regulated expression of PC-1 by FGFs may be a principal mechanism by which FGF signaling affects bone mineralization."
],
"offsets": [
[
0,
198
]
]
}
] | [
{
"id": "DS.d759.s0.e0",
"type": "compound",
"text": [
"pyrophosphate"
],
"offsets": [
[
33,
46
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "644102"
}
]
},
{
"id": "DS.d759.s0.e1",
"type": "protein",
"text": [
"FGFs"
],
"offsets": [
[
113,
117
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O10284"
},
{
"db_name": "UniProt",
"db_id": "P41444"
}
]
},
{
"id": "DS.d759.s0.e2",
"type": "protein",
"text": [
"FGF"
],
"offsets": [
[
113,
116
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O10284"
},
{
"db_name": "UniProt",
"db_id": "P41444"
}
]
}
] | [] | [] | [
{
"id": "DS.d759.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d759.s0.e0",
"arg2_id": "DS.d759.s0.e2",
"normalized": []
},
{
"id": "DS.d759.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d759.s0.e0",
"arg2_id": "DS.d759.s0.e1",
"normalized": []
}
] |
DS.d760 | 18698333 | [
{
"id": "DS.d760.s0",
"type": "",
"text": [
"In analogy to the reduction of Ca(2+) oscillation frequency, the blockers impaired HCEC contraction, NF-kappaB activation, and VCAM-1 expression."
],
"offsets": [
[
0,
145
]
]
},
{
"id": "DS.d760.s1",
"type": "",
"text": [
"Cisternal SAH-CSF induces cytosolic Ca(2+) oscillations in HCEC that results in cellular constriction, NF-kappaB activation, and VCAM-1 expression."
],
"offsets": [
[
146,
293
]
]
}
] | [
{
"id": "DS.d760.s0.e0",
"type": "compound",
"text": [
"Ca(2"
],
"offsets": [
[
31,
35
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "271"
}
]
},
{
"id": "DS.d760.s0.e1",
"type": "protein",
"text": [
"VCAM-1"
],
"offsets": [
[
127,
133
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P19320"
},
{
"db_name": "UniProt",
"db_id": "P29533"
},
{
"db_name": "UniProt",
"db_id": "P29534"
},
{
"db_name": "UniProt",
"db_id": "Q28260"
}
]
},
{
"id": "DS.d760.s1.e0",
"type": "compound",
"text": [
"Ca(2"
],
"offsets": [
[
182,
186
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "271"
}
]
},
{
"id": "DS.d760.s1.e1",
"type": "protein",
"text": [
"VCAM-1"
],
"offsets": [
[
275,
281
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P19320"
},
{
"db_name": "UniProt",
"db_id": "P29533"
},
{
"db_name": "UniProt",
"db_id": "P29534"
},
{
"db_name": "UniProt",
"db_id": "Q28260"
}
]
}
] | [] | [] | [
{
"id": "DS.d760.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d760.s0.e0",
"arg2_id": "DS.d760.s0.e1",
"normalized": []
},
{
"id": "DS.d760.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d760.s1.e0",
"arg2_id": "DS.d760.s1.e1",
"normalized": []
}
] |
DS.d761 | 18698636 | [
{
"id": "DS.d761.s0",
"type": "",
"text": [
"For proof of principle, we use L-lactate and D-lactate as representative pair of enantiomers, L-lactate oxidase as stereospecific signal generator, and cascade blue hydrazide as reactive signal amplifier to capture the produced pyruvate."
],
"offsets": [
[
0,
237
]
]
}
] | [
{
"id": "DS.d761.s0.e0",
"type": "compound",
"text": [
"L-lactate"
],
"offsets": [
[
31,
40
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "107689"
}
]
},
{
"id": "DS.d761.s0.e1",
"type": "compound",
"text": [
"D-lactate"
],
"offsets": [
[
45,
54
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "61503"
}
]
},
{
"id": "DS.d761.s0.e2",
"type": "protein",
"text": [
"lactate oxidase"
],
"offsets": [
[
96,
111
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P21795"
}
]
},
{
"id": "DS.d761.s0.e3",
"type": "compound",
"text": [
"pyruvate"
],
"offsets": [
[
228,
236
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1060"
}
]
}
] | [] | [] | [] |
DS.d762 | 18698648 | [
{
"id": "DS.d762.s0",
"type": "",
"text": [
"Escherichia coli strain PC09 (DeltaxylB, cAMP-independent CRP (crp *) mutant) expressing an NADPH-dependent xylose reductase from Candida boidinii (CbXR) was previously reported to produce xylitol from xylose while metabolizing glucose (Cirino et al."
],
"offsets": [
[
0,
250
]
]
},
{
"id": "DS.d762.s1",
"type": "",
"text": [
"Studies in which the expression of CbXR or a xylose transporter was increased suggest that enzyme activity and xylose transport are not limiting xylitol production in PC09."
],
"offsets": [
[
251,
423
]
]
},
{
"id": "DS.d762.s2",
"type": "",
"text": [
"For the case of xylose-proton symport, omitting the Zwf (glucose-6-phosphate dehydrogenase) or PntAB (membrane-bound transhydrogenase) reactions or TCA cycle activity from the model reduces the theoretical maximum yield from 9.2 to 8.8, 3.6, and 8.0 mol xylitol (mol glucose)(-1), respectively."
],
"offsets": [
[
424,
718
]
]
},
{
"id": "DS.d762.s3",
"type": "",
"text": [
"Experimentally, deleting pgi (encoding phosphoglucose isomerase) from strain PC09 improves the yield from 3.4 to 4.0 mol xylitol (mol glucose)(-1), while deleting either or both E. coli transhydrogenases (sthA and pntA) has no significant effect on the measured yield."
],
"offsets": [
[
719,
987
]
]
},
{
"id": "DS.d762.s4",
"type": "",
"text": [
"Deleting either zwf or sucC (TCA cycle) significantly reduces the yield from 3.4 to 2.0 and 2.3 mol xylitol (mol glucose)(-1), respectively."
],
"offsets": [
[
988,
1128
]
]
}
] | [
{
"id": "DS.d762.s0.e0",
"type": "protein",
"text": [
"xylose reductase"
],
"offsets": [
[
108,
124
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P38715"
}
]
},
{
"id": "DS.d762.s0.e1",
"type": "compound",
"text": [
"xylitol"
],
"offsets": [
[
189,
196
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6912"
}
]
},
{
"id": "DS.d762.s0.e2",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
228,
235
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d762.s1.e0",
"type": "protein",
"text": [
"xylose transporter"
],
"offsets": [
[
296,
314
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P96792"
}
]
},
{
"id": "DS.d762.s1.e1",
"type": "compound",
"text": [
"xylitol"
],
"offsets": [
[
396,
403
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6912"
}
]
},
{
"id": "DS.d762.s2.e0",
"type": "protein",
"text": [
"Zwf"
],
"offsets": [
[
476,
479
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O51581"
},
{
"db_name": "UniProt",
"db_id": "O54537"
},
{
"db_name": "UniProt",
"db_id": "O68282"
},
{
"db_name": "UniProt",
"db_id": "O83491"
},
{
"db_name": "UniProt",
"db_id": "O84188"
},
{
"db_name": "UniProt",
"db_id": "P0A584"
},
{
"db_name": "UniProt",
"db_id": "P0A585"
},
{
"db_name": "UniProt",
"db_id": "P0A586"
},
{
"db_name": "UniProt",
"db_id": "P0A587"
},
{
"db_name": "UniProt",
"db_id": "P0AC53"
},
{
"db_name": "UniProt",
"db_id": "P0AC54"
},
{
"db_name": "UniProt",
"db_id": "P11411"
},
{
"db_name": "UniProt",
"db_id": "P21907"
},
{
"db_name": "UniProt",
"db_id": "P29686"
},
{
"db_name": "UniProt",
"db_id": "P37986"
},
{
"db_name": "UniProt",
"db_id": "P44311"
},
{
"db_name": "UniProt",
"db_id": "P48848"
},
{
"db_name": "UniProt",
"db_id": "P48992"
},
{
"db_name": "UniProt",
"db_id": "P54547"
},
{
"db_name": "UniProt",
"db_id": "P56110"
},
{
"db_name": "UniProt",
"db_id": "P57405"
},
{
"db_name": "UniProt",
"db_id": "P73411"
},
{
"db_name": "UniProt",
"db_id": "P77809"
},
{
"db_name": "UniProt",
"db_id": "Q89AI7"
},
{
"db_name": "UniProt",
"db_id": "Q8K9M2"
},
{
"db_name": "UniProt",
"db_id": "Q8XCJ6"
},
{
"db_name": "UniProt",
"db_id": "Q9PKK8"
},
{
"db_name": "UniProt",
"db_id": "Q9X0N9"
},
{
"db_name": "UniProt",
"db_id": "Q9Z3S2"
},
{
"db_name": "UniProt",
"db_id": "Q9Z8U6"
},
{
"db_name": "UniProt",
"db_id": "Q9ZKB2"
}
]
},
{
"id": "DS.d762.s2.e1",
"type": "protein",
"text": [
"PntAB"
],
"offsets": [
[
519,
524
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0C187"
},
{
"db_name": "UniProt",
"db_id": "P51995"
},
{
"db_name": "UniProt",
"db_id": "Q2RSB3"
}
]
},
{
"id": "DS.d762.s2.e2",
"type": "compound",
"text": [
"xylitol"
],
"offsets": [
[
678,
685
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6912"
}
]
},
{
"id": "DS.d762.s3.e0",
"type": "protein",
"text": [
"pgi"
],
"offsets": [
[
744,
747
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O25781"
},
{
"db_name": "UniProt",
"db_id": "O51672"
},
{
"db_name": "UniProt",
"db_id": "O83488"
},
{
"db_name": "UniProt",
"db_id": "O84382"
},
{
"db_name": "UniProt",
"db_id": "O88015"
},
{
"db_name": "UniProt",
"db_id": "P0A0T0"
},
{
"db_name": "UniProt",
"db_id": "P0A0T1"
},
{
"db_name": "UniProt",
"db_id": "P0A6T1"
},
{
"db_name": "UniProt",
"db_id": "P0A6T2"
},
{
"db_name": "UniProt",
"db_id": "P28718"
},
{
"db_name": "UniProt",
"db_id": "P44312"
},
{
"db_name": "UniProt",
"db_id": "P47357"
},
{
"db_name": "UniProt",
"db_id": "P52029"
},
{
"db_name": "UniProt",
"db_id": "P52030"
},
{
"db_name": "UniProt",
"db_id": "P52031"
},
{
"db_name": "UniProt",
"db_id": "P52983"
},
{
"db_name": "UniProt",
"db_id": "P57636"
},
{
"db_name": "UniProt",
"db_id": "P64192"
},
{
"db_name": "UniProt",
"db_id": "P64193"
},
{
"db_name": "UniProt",
"db_id": "P64194"
},
{
"db_name": "UniProt",
"db_id": "P64195"
},
{
"db_name": "UniProt",
"db_id": "P64196"
},
{
"db_name": "UniProt",
"db_id": "P77877"
},
{
"db_name": "UniProt",
"db_id": "P78033"
},
{
"db_name": "UniProt",
"db_id": "P80860"
},
{
"db_name": "UniProt",
"db_id": "P81181"
},
{
"db_name": "UniProt",
"db_id": "P96803"
},
{
"db_name": "UniProt",
"db_id": "P99078"
},
{
"db_name": "UniProt",
"db_id": "Q0TA36"
},
{
"db_name": "UniProt",
"db_id": "Q0VR14"
},
{
"db_name": "UniProt",
"db_id": "Q11MA0"
},
{
"db_name": "UniProt",
"db_id": "Q13Z07"
},
{
"db_name": "UniProt",
"db_id": "Q165T7"
},
{
"db_name": "UniProt",
"db_id": "Q18FQ4"
},
{
"db_name": "UniProt",
"db_id": "Q1ASN4"
},
{
"db_name": "UniProt",
"db_id": "Q1BH79"
},
{
"db_name": "UniProt",
"db_id": "Q1CSA0"
},
{
"db_name": "UniProt",
"db_id": "Q1CX51"
},
{
"db_name": "UniProt",
"db_id": "Q1GAY0"
},
{
"db_name": "UniProt",
"db_id": "Q1GJQ5"
},
{
"db_name": "UniProt",
"db_id": "Q1GTU1"
},
{
"db_name": "UniProt",
"db_id": "Q1H1P4"
},
{
"db_name": "UniProt",
"db_id": "Q1IYT4"
},
{
"db_name": "UniProt",
"db_id": "Q1J8N2"
},
{
"db_name": "UniProt",
"db_id": "Q1JDQ8"
},
{
"db_name": "UniProt",
"db_id": "Q1JIS1"
},
{
"db_name": "UniProt",
"db_id": "Q1JNM4"
},
{
"db_name": "UniProt",
"db_id": "Q1LM68"
},
{
"db_name": "UniProt",
"db_id": "Q1LU73"
},
{
"db_name": "UniProt",
"db_id": "Q1MM06"
},
{
"db_name": "UniProt",
"db_id": "Q1QEK1"
},
{
"db_name": "UniProt",
"db_id": "Q1R3R3"
},
{
"db_name": "UniProt",
"db_id": "Q1WUR2"
},
{
"db_name": "UniProt",
"db_id": "Q21M11"
},
{
"db_name": "UniProt",
"db_id": "Q21ZD5"
},
{
"db_name": "UniProt",
"db_id": "Q24VW9"
},
{
"db_name": "UniProt",
"db_id": "Q255I6"
},
{
"db_name": "UniProt",
"db_id": "Q28QX4"
},
{
"db_name": "UniProt",
"db_id": "Q2A2C5"
},
{
"db_name": "UniProt",
"db_id": "Q2FIB3"
},
{
"db_name": "UniProt",
"db_id": "Q2FZU0"
},
{
"db_name": "UniProt",
"db_id": "Q2G7C4"
},
{
"db_name": "UniProt",
"db_id": "Q2IE39"
},
{
"db_name": "UniProt",
"db_id": "Q2JH03"
},
{
"db_name": "UniProt",
"db_id": "Q2JHU0"
},
{
"db_name": "UniProt",
"db_id": "Q2JX86"
},
{
"db_name": "UniProt",
"db_id": "Q2KCY8"
},
{
"db_name": "UniProt",
"db_id": "Q2KYE9"
},
{
"db_name": "UniProt",
"db_id": "Q2LRD0"
},
{
"db_name": "UniProt",
"db_id": "Q2NJ38"
},
{
"db_name": "UniProt",
"db_id": "Q2NR04"
},
{
"db_name": "UniProt",
"db_id": "Q2P380"
},
{
"db_name": "UniProt",
"db_id": "Q2RQ51"
},
{
"db_name": "UniProt",
"db_id": "Q2S8W1"
},
{
"db_name": "UniProt",
"db_id": "Q2SS24"
},
{
"db_name": "UniProt",
"db_id": "Q2SWP6"
},
{
"db_name": "UniProt",
"db_id": "Q2VYV7"
},
{
"db_name": "UniProt",
"db_id": "Q2YBU4"
},
{
"db_name": "UniProt",
"db_id": "Q2YPF3"
},
{
"db_name": "UniProt",
"db_id": "Q2YWS3"
},
{
"db_name": "UniProt",
"db_id": "Q31AX5"
},
{
"db_name": "UniProt",
"db_id": "Q31I19"
},
{
"db_name": "UniProt",
"db_id": "Q31LL0"
},
{
"db_name": "UniProt",
"db_id": "Q31TX1"
},
{
"db_name": "UniProt",
"db_id": "Q328X7"
},
{
"db_name": "UniProt",
"db_id": "Q38WF1"
},
{
"db_name": "UniProt",
"db_id": "Q39FF4"
},
{
"db_name": "UniProt",
"db_id": "Q39SU1"
},
{
"db_name": "UniProt",
"db_id": "Q3A201"
},
{
"db_name": "UniProt",
"db_id": "Q3AFH3"
},
{
"db_name": "UniProt",
"db_id": "Q3AJU7"
},
{
"db_name": "UniProt",
"db_id": "Q3ASZ0"
},
{
"db_name": "UniProt",
"db_id": "Q3AXV8"
},
{
"db_name": "UniProt",
"db_id": "Q3B3Q8"
},
{
"db_name": "UniProt",
"db_id": "Q3BUL3"
},
{
"db_name": "UniProt",
"db_id": "Q3IKH4"
},
{
"db_name": "UniProt",
"db_id": "Q3IMS0"
},
{
"db_name": "UniProt",
"db_id": "Q3J2U4"
},
{
"db_name": "UniProt",
"db_id": "Q3JCN1"
},
{
"db_name": "UniProt",
"db_id": "Q3JRE2"
},
{
"db_name": "UniProt",
"db_id": "Q3K2Y2"
},
{
"db_name": "UniProt",
"db_id": "Q3K6Q4"
},
{
"db_name": "UniProt",
"db_id": "Q3KLX6"
},
{
"db_name": "UniProt",
"db_id": "Q3M6S3"
},
{
"db_name": "UniProt",
"db_id": "Q3YUW0"
},
{
"db_name": "UniProt",
"db_id": "Q46L16"
},
{
"db_name": "UniProt",
"db_id": "Q47IJ3"
},
{
"db_name": "UniProt",
"db_id": "Q48N88"
},
{
"db_name": "UniProt",
"db_id": "Q48VF9"
},
{
"db_name": "UniProt",
"db_id": "Q491V0"
},
{
"db_name": "UniProt",
"db_id": "Q49WA1"
},
{
"db_name": "UniProt",
"db_id": "Q4A5S9"
},
{
"db_name": "UniProt",
"db_id": "Q4A7J2"
},
{
"db_name": "UniProt",
"db_id": "Q4A9F3"
},
{
"db_name": "UniProt",
"db_id": "Q4FVH5"
},
{
"db_name": "UniProt",
"db_id": "Q4JX51"
},
{
"db_name": "UniProt",
"db_id": "Q4K5Y1"
},
{
"db_name": "UniProt",
"db_id": "Q4L4X8"
},
{
"db_name": "UniProt",
"db_id": "Q4QL07"
},
{
"db_name": "UniProt",
"db_id": "Q4UTV8"
},
{
"db_name": "UniProt",
"db_id": "Q4ZY88"
},
{
"db_name": "UniProt",
"db_id": "Q57F73"
},
{
"db_name": "UniProt",
"db_id": "Q57H06"
},
{
"db_name": "UniProt",
"db_id": "Q59000"
},
{
"db_name": "UniProt",
"db_id": "Q59088"
},
{
"db_name": "UniProt",
"db_id": "Q5E847"
},
{
"db_name": "UniProt",
"db_id": "Q5FL04"
},
{
"db_name": "UniProt",
"db_id": "Q5H0A7"
},
{
"db_name": "UniProt",
"db_id": "Q5HHC2"
},
{
"db_name": "UniProt",
"db_id": "Q5HQJ9"
},
{
"db_name": "UniProt",
"db_id": "Q5KVS7"
},
{
"db_name": "UniProt",
"db_id": "Q5L5E1"
},
{
"db_name": "UniProt",
"db_id": "Q5L9E3"
},
{
"db_name": "UniProt",
"db_id": "Q5LRS9"
},
{
"db_name": "UniProt",
"db_id": "Q5M1N9"
},
{
"db_name": "UniProt",
"db_id": "Q5N0B4"
},
{
"db_name": "UniProt",
"db_id": "Q5NFC4"
},
{
"db_name": "UniProt",
"db_id": "Q5P0T4"
},
{
"db_name": "UniProt",
"db_id": "Q5PL07"
},
{
"db_name": "UniProt",
"db_id": "Q5QWW0"
},
{
"db_name": "UniProt",
"db_id": "Q5SLL6"
},
{
"db_name": "UniProt",
"db_id": "Q5UXU0"
},
{
"db_name": "UniProt",
"db_id": "Q5WDX0"
},
{
"db_name": "UniProt",
"db_id": "Q5WYE0"
},
{
"db_name": "UniProt",
"db_id": "Q5X6Y8"
},
{
"db_name": "UniProt",
"db_id": "Q5XE09"
},
{
"db_name": "UniProt",
"db_id": "Q5YPP1"
},
{
"db_name": "UniProt",
"db_id": "Q5ZXH2"
},
{
"db_name": "UniProt",
"db_id": "Q600A8"
},
{
"db_name": "UniProt",
"db_id": "Q609I7"
},
{
"db_name": "UniProt",
"db_id": "Q62JL8"
},
{
"db_name": "UniProt",
"db_id": "Q632G4"
},
{
"db_name": "UniProt",
"db_id": "Q63V31"
},
{
"db_name": "UniProt",
"db_id": "Q64PM7"
},
{
"db_name": "UniProt",
"db_id": "Q65FL6"
},
{
"db_name": "UniProt",
"db_id": "Q65TC2"
},
{
"db_name": "UniProt",
"db_id": "Q660E3"
},
{
"db_name": "UniProt",
"db_id": "Q664W9"
},
{
"db_name": "UniProt",
"db_id": "Q67QQ0"
},
{
"db_name": "UniProt",
"db_id": "Q6A5X5"
},
{
"db_name": "UniProt",
"db_id": "Q6AQ48"
},
{
"db_name": "UniProt",
"db_id": "Q6D022"
},
{
"db_name": "UniProt",
"db_id": "Q6F1L2"
},
{
"db_name": "UniProt",
"db_id": "Q6G0T9"
},
{
"db_name": "UniProt",
"db_id": "Q6GAW4"
},
{
"db_name": "UniProt",
"db_id": "Q6GIC6"
},
{
"db_name": "UniProt",
"db_id": "Q6HC08"
},
{
"db_name": "UniProt",
"db_id": "Q6KH90"
},
{
"db_name": "UniProt",
"db_id": "Q6LM51"
},
{
"db_name": "UniProt",
"db_id": "Q6LXQ4"
},
{
"db_name": "UniProt",
"db_id": "Q6MD44"
},
{
"db_name": "UniProt",
"db_id": "Q6MTA3"
},
{
"db_name": "UniProt",
"db_id": "Q6NIE5"
},
{
"db_name": "UniProt",
"db_id": "Q6YQU0"
},
{
"db_name": "UniProt",
"db_id": "Q71X61"
},
{
"db_name": "UniProt",
"db_id": "Q72GY6"
},
{
"db_name": "UniProt",
"db_id": "Q72MT7"
},
{
"db_name": "UniProt",
"db_id": "Q72YI4"
},
{
"db_name": "UniProt",
"db_id": "Q73K18"
},
{
"db_name": "UniProt",
"db_id": "Q742E4"
},
{
"db_name": "UniProt",
"db_id": "Q74DK5"
},
{
"db_name": "UniProt",
"db_id": "Q74K31"
},
{
"db_name": "UniProt",
"db_id": "Q7MH97"
},
{
"db_name": "UniProt",
"db_id": "Q7MUV9"
},
{
"db_name": "UniProt",
"db_id": "Q7MZB4"
},
{
"db_name": "UniProt",
"db_id": "Q7NJY9"
},
{
"db_name": "UniProt",
"db_id": "Q7U6T0"
},
{
"db_name": "UniProt",
"db_id": "Q7V1I1"
},
{
"db_name": "UniProt",
"db_id": "Q7V7M6"
},
{
"db_name": "UniProt",
"db_id": "Q7VBZ6"
},
{
"db_name": "UniProt",
"db_id": "Q7VNR9"
},
{
"db_name": "UniProt",
"db_id": "Q7VRI4"
},
{
"db_name": "UniProt",
"db_id": "Q7VUF4"
},
{
"db_name": "UniProt",
"db_id": "Q7W197"
},
{
"db_name": "UniProt",
"db_id": "Q7WP01"
},
{
"db_name": "UniProt",
"db_id": "Q816G0"
},
{
"db_name": "UniProt",
"db_id": "Q81K75"
},
{
"db_name": "UniProt",
"db_id": "Q822E7"
},
{
"db_name": "UniProt",
"db_id": "Q82SP4"
},
{
"db_name": "UniProt",
"db_id": "Q835G1"
},
{
"db_name": "UniProt",
"db_id": "Q83D91"
},
{
"db_name": "UniProt",
"db_id": "Q83XM3"
},
{
"db_name": "UniProt",
"db_id": "Q848I4"
},
{
"db_name": "UniProt",
"db_id": "Q87EV7"
},
{
"db_name": "UniProt",
"db_id": "Q87L81"
},
{
"db_name": "UniProt",
"db_id": "Q888Q7"
},
{
"db_name": "UniProt",
"db_id": "Q88UI4"
},
{
"db_name": "UniProt",
"db_id": "Q891H2"
},
{
"db_name": "UniProt",
"db_id": "Q89A35"
},
{
"db_name": "UniProt",
"db_id": "Q8A5W2"
},
{
"db_name": "UniProt",
"db_id": "Q8CT80"
},
{
"db_name": "UniProt",
"db_id": "Q8D1V8"
},
{
"db_name": "UniProt",
"db_id": "Q8DCK7"
},
{
"db_name": "UniProt",
"db_id": "Q8DKY2"
},
{
"db_name": "UniProt",
"db_id": "Q8DN74"
},
{
"db_name": "UniProt",
"db_id": "Q8EBH1"
},
{
"db_name": "UniProt",
"db_id": "Q8ENY8"
},
{
"db_name": "UniProt",
"db_id": "Q8EVU1"
},
{
"db_name": "UniProt",
"db_id": "Q8EZG6"
},
{
"db_name": "UniProt",
"db_id": "Q8FB44"
},
{
"db_name": "UniProt",
"db_id": "Q8FR39"
},
{
"db_name": "UniProt",
"db_id": "Q8G2N3"
},
{
"db_name": "UniProt",
"db_id": "Q8G7I6"
},
{
"db_name": "UniProt",
"db_id": "Q8K8Q6"
},
{
"db_name": "UniProt",
"db_id": "Q8K910"
},
{
"db_name": "UniProt",
"db_id": "Q8KDQ7"
},
{
"db_name": "UniProt",
"db_id": "Q8L1Z9"
},
{
"db_name": "UniProt",
"db_id": "Q8NS31"
},
{
"db_name": "UniProt",
"db_id": "Q8NXF1"
},
{
"db_name": "UniProt",
"db_id": "Q8P2R3"
},
{
"db_name": "UniProt",
"db_id": "Q8P9S7"
},
{
"db_name": "UniProt",
"db_id": "Q8R924"
},
{
"db_name": "UniProt",
"db_id": "Q8RHH5"
},
{
"db_name": "UniProt",
"db_id": "Q8UI94"
},
{
"db_name": "UniProt",
"db_id": "Q8VVB7"
},
{
"db_name": "UniProt",
"db_id": "Q8XI54"
},
{
"db_name": "UniProt",
"db_id": "Q8XYN9"
},
{
"db_name": "UniProt",
"db_id": "Q8Y4R7"
},
{
"db_name": "UniProt",
"db_id": "Q8YF86"
},
{
"db_name": "UniProt",
"db_id": "Q8YY05"
},
{
"db_name": "UniProt",
"db_id": "Q8Z1U7"
},
{
"db_name": "UniProt",
"db_id": "Q8ZAS2"
},
{
"db_name": "UniProt",
"db_id": "Q8ZKI4"
},
{
"db_name": "UniProt",
"db_id": "Q928R6"
},
{
"db_name": "UniProt",
"db_id": "Q92SC4"
},
{
"db_name": "UniProt",
"db_id": "Q97FP8"
},
{
"db_name": "UniProt",
"db_id": "Q97NG0"
},
{
"db_name": "UniProt",
"db_id": "Q98BV5"
},
{
"db_name": "UniProt",
"db_id": "Q98R79"
},
{
"db_name": "UniProt",
"db_id": "Q9A1L1"
},
{
"db_name": "UniProt",
"db_id": "Q9ABK5"
},
{
"db_name": "UniProt",
"db_id": "Q9CD75"
},
{
"db_name": "UniProt",
"db_id": "Q9CNL2"
},
{
"db_name": "UniProt",
"db_id": "Q9HNQ6"
},
{
"db_name": "UniProt",
"db_id": "Q9HV67"
},
{
"db_name": "UniProt",
"db_id": "Q9K7L8"
},
{
"db_name": "UniProt",
"db_id": "Q9KUY4"
},
{
"db_name": "UniProt",
"db_id": "Q9KX58"
},
{
"db_name": "UniProt",
"db_id": "Q9PGR6"
},
{
"db_name": "UniProt",
"db_id": "Q9PK16"
},
{
"db_name": "UniProt",
"db_id": "Q9PMD4"
},
{
"db_name": "UniProt",
"db_id": "Q9RDY2"
},
{
"db_name": "UniProt",
"db_id": "Q9RMC1"
},
{
"db_name": "UniProt",
"db_id": "Q9RTL8"
},
{
"db_name": "UniProt",
"db_id": "Q9X1A5"
},
{
"db_name": "UniProt",
"db_id": "Q9X670"
},
{
"db_name": "UniProt",
"db_id": "Q9Z6N4"
},
{
"db_name": "UniProt",
"db_id": "Q9ZK49"
}
]
},
{
"id": "DS.d762.s3.e1",
"type": "protein",
"text": [
"phosphoglucose isomerase"
],
"offsets": [
[
758,
782
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O25781"
},
{
"db_name": "UniProt",
"db_id": "O51672"
},
{
"db_name": "UniProt",
"db_id": "O59618"
},
{
"db_name": "UniProt",
"db_id": "O66954"
},
{
"db_name": "UniProt",
"db_id": "O82059"
},
{
"db_name": "UniProt",
"db_id": "O83488"
},
{
"db_name": "UniProt",
"db_id": "O84382"
},
{
"db_name": "UniProt",
"db_id": "P06744"
},
{
"db_name": "UniProt",
"db_id": "P06745"
},
{
"db_name": "UniProt",
"db_id": "P08059"
},
{
"db_name": "UniProt",
"db_id": "P0A0T0"
},
{
"db_name": "UniProt",
"db_id": "P0A0T1"
},
{
"db_name": "UniProt",
"db_id": "P0A6T1"
},
{
"db_name": "UniProt",
"db_id": "P0A6T2"
},
{
"db_name": "UniProt",
"db_id": "P12341"
},
{
"db_name": "UniProt",
"db_id": "P12709"
},
{
"db_name": "UniProt",
"db_id": "P13377"
},
{
"db_name": "UniProt",
"db_id": "P18240"
},
{
"db_name": "UniProt",
"db_id": "P28718"
},
{
"db_name": "UniProt",
"db_id": "P29333"
},
{
"db_name": "UniProt",
"db_id": "P34795"
},
{
"db_name": "UniProt",
"db_id": "P34796"
},
{
"db_name": "UniProt",
"db_id": "P34797"
},
{
"db_name": "UniProt",
"db_id": "P42861"
},
{
"db_name": "UniProt",
"db_id": "P44312"
},
{
"db_name": "UniProt",
"db_id": "P46479"
},
{
"db_name": "UniProt",
"db_id": "P47357"
},
{
"db_name": "UniProt",
"db_id": "P49105"
},
{
"db_name": "UniProt",
"db_id": "P50309"
},
{
"db_name": "UniProt",
"db_id": "P52029"
},
{
"db_name": "UniProt",
"db_id": "P52030"
},
{
"db_name": "UniProt",
"db_id": "P52031"
},
{
"db_name": "UniProt",
"db_id": "P52983"
},
{
"db_name": "UniProt",
"db_id": "P54234"
},
{
"db_name": "UniProt",
"db_id": "P54235"
},
{
"db_name": "UniProt",
"db_id": "P54236"
},
{
"db_name": "UniProt",
"db_id": "P54237"
},
{
"db_name": "UniProt",
"db_id": "P54238"
},
{
"db_name": "UniProt",
"db_id": "P54239"
},
{
"db_name": "UniProt",
"db_id": "P54240"
},
{
"db_name": "UniProt",
"db_id": "P54241"
},
{
"db_name": "UniProt",
"db_id": "P54242"
},
{
"db_name": "UniProt",
"db_id": "P54243"
},
{
"db_name": "UniProt",
"db_id": "P57636"
},
{
"db_name": "UniProt",
"db_id": "P64192"
},
{
"db_name": "UniProt",
"db_id": "P64193"
},
{
"db_name": "UniProt",
"db_id": "P64194"
},
{
"db_name": "UniProt",
"db_id": "P64195"
},
{
"db_name": "UniProt",
"db_id": "P64196"
},
{
"db_name": "UniProt",
"db_id": "P77877"
},
{
"db_name": "UniProt",
"db_id": "P78033"
},
{
"db_name": "UniProt",
"db_id": "P78917"
},
{
"db_name": "UniProt",
"db_id": "P80860"
},
{
"db_name": "UniProt",
"db_id": "P81181"
},
{
"db_name": "UniProt",
"db_id": "P83194"
},
{
"db_name": "UniProt",
"db_id": "P83780"
},
{
"db_name": "UniProt",
"db_id": "P84140"
},
{
"db_name": "UniProt",
"db_id": "P96803"
},
{
"db_name": "UniProt",
"db_id": "P99078"
},
{
"db_name": "UniProt",
"db_id": "Q0TA36"
},
{
"db_name": "UniProt",
"db_id": "Q0VR14"
},
{
"db_name": "UniProt",
"db_id": "Q11MA0"
},
{
"db_name": "UniProt",
"db_id": "Q13Z07"
},
{
"db_name": "UniProt",
"db_id": "Q165T7"
},
{
"db_name": "UniProt",
"db_id": "Q18FQ4"
},
{
"db_name": "UniProt",
"db_id": "Q1ASN4"
},
{
"db_name": "UniProt",
"db_id": "Q1BH79"
},
{
"db_name": "UniProt",
"db_id": "Q1CSA0"
},
{
"db_name": "UniProt",
"db_id": "Q1CX51"
},
{
"db_name": "UniProt",
"db_id": "Q1GAY0"
},
{
"db_name": "UniProt",
"db_id": "Q1GJQ5"
},
{
"db_name": "UniProt",
"db_id": "Q1GTU1"
},
{
"db_name": "UniProt",
"db_id": "Q1H1P4"
},
{
"db_name": "UniProt",
"db_id": "Q1IYT4"
},
{
"db_name": "UniProt",
"db_id": "Q1J8N2"
},
{
"db_name": "UniProt",
"db_id": "Q1JDQ8"
},
{
"db_name": "UniProt",
"db_id": "Q1JIS1"
},
{
"db_name": "UniProt",
"db_id": "Q1JNM4"
},
{
"db_name": "UniProt",
"db_id": "Q1LM68"
},
{
"db_name": "UniProt",
"db_id": "Q1LU73"
},
{
"db_name": "UniProt",
"db_id": "Q1MM06"
},
{
"db_name": "UniProt",
"db_id": "Q1QEK1"
},
{
"db_name": "UniProt",
"db_id": "Q1R3R3"
},
{
"db_name": "UniProt",
"db_id": "Q1WUR2"
},
{
"db_name": "UniProt",
"db_id": "Q21M11"
},
{
"db_name": "UniProt",
"db_id": "Q21ZD5"
},
{
"db_name": "UniProt",
"db_id": "Q24VW9"
},
{
"db_name": "UniProt",
"db_id": "Q255I6"
},
{
"db_name": "UniProt",
"db_id": "Q28QX4"
},
{
"db_name": "UniProt",
"db_id": "Q2A2C5"
},
{
"db_name": "UniProt",
"db_id": "Q2FIB3"
},
{
"db_name": "UniProt",
"db_id": "Q2FZU0"
},
{
"db_name": "UniProt",
"db_id": "Q2G7C4"
},
{
"db_name": "UniProt",
"db_id": "Q2IE39"
},
{
"db_name": "UniProt",
"db_id": "Q2JH03"
},
{
"db_name": "UniProt",
"db_id": "Q2JHU0"
},
{
"db_name": "UniProt",
"db_id": "Q2JX86"
},
{
"db_name": "UniProt",
"db_id": "Q2KCY8"
},
{
"db_name": "UniProt",
"db_id": "Q2KYE9"
},
{
"db_name": "UniProt",
"db_id": "Q2LRD0"
},
{
"db_name": "UniProt",
"db_id": "Q2NJ38"
},
{
"db_name": "UniProt",
"db_id": "Q2NR04"
},
{
"db_name": "UniProt",
"db_id": "Q2P380"
},
{
"db_name": "UniProt",
"db_id": "Q2RQ51"
},
{
"db_name": "UniProt",
"db_id": "Q2S8W1"
},
{
"db_name": "UniProt",
"db_id": "Q2SS24"
},
{
"db_name": "UniProt",
"db_id": "Q2SWP6"
},
{
"db_name": "UniProt",
"db_id": "Q2VYV7"
},
{
"db_name": "UniProt",
"db_id": "Q2YBU4"
},
{
"db_name": "UniProt",
"db_id": "Q2YPF3"
},
{
"db_name": "UniProt",
"db_id": "Q2YWS3"
},
{
"db_name": "UniProt",
"db_id": "Q31AX5"
},
{
"db_name": "UniProt",
"db_id": "Q31I19"
},
{
"db_name": "UniProt",
"db_id": "Q31LL0"
},
{
"db_name": "UniProt",
"db_id": "Q31TX1"
},
{
"db_name": "UniProt",
"db_id": "Q328X7"
},
{
"db_name": "UniProt",
"db_id": "Q38WF1"
},
{
"db_name": "UniProt",
"db_id": "Q39FF4"
},
{
"db_name": "UniProt",
"db_id": "Q39SU1"
},
{
"db_name": "UniProt",
"db_id": "Q3A201"
},
{
"db_name": "UniProt",
"db_id": "Q3AFH3"
},
{
"db_name": "UniProt",
"db_id": "Q3AJU7"
},
{
"db_name": "UniProt",
"db_id": "Q3ASZ0"
},
{
"db_name": "UniProt",
"db_id": "Q3AXV8"
},
{
"db_name": "UniProt",
"db_id": "Q3B3Q8"
},
{
"db_name": "UniProt",
"db_id": "Q3BUL3"
},
{
"db_name": "UniProt",
"db_id": "Q3IKH4"
},
{
"db_name": "UniProt",
"db_id": "Q3IMS0"
},
{
"db_name": "UniProt",
"db_id": "Q3J2U4"
},
{
"db_name": "UniProt",
"db_id": "Q3JCN1"
},
{
"db_name": "UniProt",
"db_id": "Q3JRE2"
},
{
"db_name": "UniProt",
"db_id": "Q3K2Y2"
},
{
"db_name": "UniProt",
"db_id": "Q3K6Q4"
},
{
"db_name": "UniProt",
"db_id": "Q3KLX6"
},
{
"db_name": "UniProt",
"db_id": "Q3M6S3"
},
{
"db_name": "UniProt",
"db_id": "Q3YUW0"
},
{
"db_name": "UniProt",
"db_id": "Q3ZBD7"
},
{
"db_name": "UniProt",
"db_id": "Q44407"
},
{
"db_name": "UniProt",
"db_id": "Q46L16"
},
{
"db_name": "UniProt",
"db_id": "Q47IJ3"
},
{
"db_name": "UniProt",
"db_id": "Q48N88"
},
{
"db_name": "UniProt",
"db_id": "Q48VF9"
},
{
"db_name": "UniProt",
"db_id": "Q491V0"
},
{
"db_name": "UniProt",
"db_id": "Q49WA1"
},
{
"db_name": "UniProt",
"db_id": "Q4A5S9"
},
{
"db_name": "UniProt",
"db_id": "Q4A7J2"
},
{
"db_name": "UniProt",
"db_id": "Q4A9F3"
},
{
"db_name": "UniProt",
"db_id": "Q4FVH5"
},
{
"db_name": "UniProt",
"db_id": "Q4JCA7"
},
{
"db_name": "UniProt",
"db_id": "Q4JX51"
},
{
"db_name": "UniProt",
"db_id": "Q4K5Y1"
},
{
"db_name": "UniProt",
"db_id": "Q4L4X8"
},
{
"db_name": "UniProt",
"db_id": "Q4QL07"
},
{
"db_name": "UniProt",
"db_id": "Q4R591"
},
{
"db_name": "UniProt",
"db_id": "Q4UTV8"
},
{
"db_name": "UniProt",
"db_id": "Q4ZY88"
},
{
"db_name": "UniProt",
"db_id": "Q57F73"
},
{
"db_name": "UniProt",
"db_id": "Q57H06"
},
{
"db_name": "UniProt",
"db_id": "Q59000"
},
{
"db_name": "UniProt",
"db_id": "Q59088"
},
{
"db_name": "UniProt",
"db_id": "Q5E847"
},
{
"db_name": "UniProt",
"db_id": "Q5FL04"
},
{
"db_name": "UniProt",
"db_id": "Q5H0A7"
},
{
"db_name": "UniProt",
"db_id": "Q5HHC2"
},
{
"db_name": "UniProt",
"db_id": "Q5HQJ9"
},
{
"db_name": "UniProt",
"db_id": "Q5JE38"
},
{
"db_name": "UniProt",
"db_id": "Q5KVS7"
},
{
"db_name": "UniProt",
"db_id": "Q5L5E1"
},
{
"db_name": "UniProt",
"db_id": "Q5L9E3"
},
{
"db_name": "UniProt",
"db_id": "Q5LRS9"
},
{
"db_name": "UniProt",
"db_id": "Q5M1N9"
},
{
"db_name": "UniProt",
"db_id": "Q5N0B4"
},
{
"db_name": "UniProt",
"db_id": "Q5NFC4"
},
{
"db_name": "UniProt",
"db_id": "Q5P0T4"
},
{
"db_name": "UniProt",
"db_id": "Q5PL07"
},
{
"db_name": "UniProt",
"db_id": "Q5QWW0"
},
{
"db_name": "UniProt",
"db_id": "Q5R4E3"
},
{
"db_name": "UniProt",
"db_id": "Q5SLL6"
},
{
"db_name": "UniProt",
"db_id": "Q5UXU0"
},
{
"db_name": "UniProt",
"db_id": "Q5WDX0"
},
{
"db_name": "UniProt",
"db_id": "Q5WYE0"
},
{
"db_name": "UniProt",
"db_id": "Q5X6Y8"
},
{
"db_name": "UniProt",
"db_id": "Q5XE09"
},
{
"db_name": "UniProt",
"db_id": "Q5YPP1"
},
{
"db_name": "UniProt",
"db_id": "Q5ZXH2"
},
{
"db_name": "UniProt",
"db_id": "Q600A8"
},
{
"db_name": "UniProt",
"db_id": "Q609I7"
},
{
"db_name": "UniProt",
"db_id": "Q62JL8"
},
{
"db_name": "UniProt",
"db_id": "Q632G4"
},
{
"db_name": "UniProt",
"db_id": "Q63V31"
},
{
"db_name": "UniProt",
"db_id": "Q64PM7"
},
{
"db_name": "UniProt",
"db_id": "Q65FL6"
},
{
"db_name": "UniProt",
"db_id": "Q65TC2"
},
{
"db_name": "UniProt",
"db_id": "Q660E3"
},
{
"db_name": "UniProt",
"db_id": "Q664W9"
},
{
"db_name": "UniProt",
"db_id": "Q67QQ0"
},
{
"db_name": "UniProt",
"db_id": "Q6A5X5"
},
{
"db_name": "UniProt",
"db_id": "Q6AQ48"
},
{
"db_name": "UniProt",
"db_id": "Q6D022"
},
{
"db_name": "UniProt",
"db_id": "Q6F1L2"
},
{
"db_name": "UniProt",
"db_id": "Q6FRW1"
},
{
"db_name": "UniProt",
"db_id": "Q6G0T9"
},
{
"db_name": "UniProt",
"db_id": "Q6GAW4"
},
{
"db_name": "UniProt",
"db_id": "Q6GIC6"
},
{
"db_name": "UniProt",
"db_id": "Q6HC08"
},
{
"db_name": "UniProt",
"db_id": "Q6KH90"
},
{
"db_name": "UniProt",
"db_id": "Q6LM51"
},
{
"db_name": "UniProt",
"db_id": "Q6LXQ4"
},
{
"db_name": "UniProt",
"db_id": "Q6MD44"
},
{
"db_name": "UniProt",
"db_id": "Q6MTA3"
},
{
"db_name": "UniProt",
"db_id": "Q6NIE5"
},
{
"db_name": "UniProt",
"db_id": "Q6YQU0"
},
{
"db_name": "UniProt",
"db_id": "Q711G1"
},
{
"db_name": "UniProt",
"db_id": "Q71X61"
},
{
"db_name": "UniProt",
"db_id": "Q72GY6"
},
{
"db_name": "UniProt",
"db_id": "Q72MT7"
},
{
"db_name": "UniProt",
"db_id": "Q72YI4"
},
{
"db_name": "UniProt",
"db_id": "Q73K18"
},
{
"db_name": "UniProt",
"db_id": "Q742E4"
},
{
"db_name": "UniProt",
"db_id": "Q74DK5"
},
{
"db_name": "UniProt",
"db_id": "Q74K31"
},
{
"db_name": "UniProt",
"db_id": "Q758L0"
},
{
"db_name": "UniProt",
"db_id": "Q7MH97"
},
{
"db_name": "UniProt",
"db_id": "Q7MUV9"
},
{
"db_name": "UniProt",
"db_id": "Q7MZB4"
},
{
"db_name": "UniProt",
"db_id": "Q7NJY9"
},
{
"db_name": "UniProt",
"db_id": "Q7S986"
},
{
"db_name": "UniProt",
"db_id": "Q7U6T0"
},
{
"db_name": "UniProt",
"db_id": "Q7V1I1"
},
{
"db_name": "UniProt",
"db_id": "Q7V7M6"
},
{
"db_name": "UniProt",
"db_id": "Q7VBZ6"
},
{
"db_name": "UniProt",
"db_id": "Q7VNR9"
},
{
"db_name": "UniProt",
"db_id": "Q7VRI4"
},
{
"db_name": "UniProt",
"db_id": "Q7VUF4"
},
{
"db_name": "UniProt",
"db_id": "Q7W197"
},
{
"db_name": "UniProt",
"db_id": "Q7WP01"
},
{
"db_name": "UniProt",
"db_id": "Q816G0"
},
{
"db_name": "UniProt",
"db_id": "Q81K75"
},
{
"db_name": "UniProt",
"db_id": "Q822E7"
},
{
"db_name": "UniProt",
"db_id": "Q82SP4"
},
{
"db_name": "UniProt",
"db_id": "Q835G1"
},
{
"db_name": "UniProt",
"db_id": "Q83D91"
},
{
"db_name": "UniProt",
"db_id": "Q83XM3"
},
{
"db_name": "UniProt",
"db_id": "Q848I4"
},
{
"db_name": "UniProt",
"db_id": "Q87EV7"
},
{
"db_name": "UniProt",
"db_id": "Q87L81"
},
{
"db_name": "UniProt",
"db_id": "Q888Q7"
},
{
"db_name": "UniProt",
"db_id": "Q88UI4"
},
{
"db_name": "UniProt",
"db_id": "Q891H2"
},
{
"db_name": "UniProt",
"db_id": "Q89A35"
},
{
"db_name": "UniProt",
"db_id": "Q8A5W2"
},
{
"db_name": "UniProt",
"db_id": "Q8CT80"
},
{
"db_name": "UniProt",
"db_id": "Q8D1V8"
},
{
"db_name": "UniProt",
"db_id": "Q8DCK7"
},
{
"db_name": "UniProt",
"db_id": "Q8DKY2"
},
{
"db_name": "UniProt",
"db_id": "Q8DN74"
},
{
"db_name": "UniProt",
"db_id": "Q8EBH1"
},
{
"db_name": "UniProt",
"db_id": "Q8ENY8"
},
{
"db_name": "UniProt",
"db_id": "Q8EVU1"
},
{
"db_name": "UniProt",
"db_id": "Q8EZG6"
},
{
"db_name": "UniProt",
"db_id": "Q8FB44"
},
{
"db_name": "UniProt",
"db_id": "Q8FR39"
},
{
"db_name": "UniProt",
"db_id": "Q8G2N3"
},
{
"db_name": "UniProt",
"db_id": "Q8G7I6"
},
{
"db_name": "UniProt",
"db_id": "Q8K8Q6"
},
{
"db_name": "UniProt",
"db_id": "Q8K910"
},
{
"db_name": "UniProt",
"db_id": "Q8KDQ7"
},
{
"db_name": "UniProt",
"db_id": "Q8L1Z9"
},
{
"db_name": "UniProt",
"db_id": "Q8NS31"
},
{
"db_name": "UniProt",
"db_id": "Q8NXF1"
},
{
"db_name": "UniProt",
"db_id": "Q8P2R3"
},
{
"db_name": "UniProt",
"db_id": "Q8P9S7"
},
{
"db_name": "UniProt",
"db_id": "Q8R924"
},
{
"db_name": "UniProt",
"db_id": "Q8RHH5"
},
{
"db_name": "UniProt",
"db_id": "Q8SRY1"
},
{
"db_name": "UniProt",
"db_id": "Q8UI94"
},
{
"db_name": "UniProt",
"db_id": "Q8VVB7"
},
{
"db_name": "UniProt",
"db_id": "Q8XI54"
},
{
"db_name": "UniProt",
"db_id": "Q8XYN9"
},
{
"db_name": "UniProt",
"db_id": "Q8Y4R7"
},
{
"db_name": "UniProt",
"db_id": "Q8YF86"
},
{
"db_name": "UniProt",
"db_id": "Q8YY05"
},
{
"db_name": "UniProt",
"db_id": "Q8Z1U7"
},
{
"db_name": "UniProt",
"db_id": "Q8ZAS2"
},
{
"db_name": "UniProt",
"db_id": "Q8ZKI4"
},
{
"db_name": "UniProt",
"db_id": "Q8ZWV0"
},
{
"db_name": "UniProt",
"db_id": "Q928R6"
},
{
"db_name": "UniProt",
"db_id": "Q92SC4"
},
{
"db_name": "UniProt",
"db_id": "Q96YC2"
},
{
"db_name": "UniProt",
"db_id": "Q978F3"
},
{
"db_name": "UniProt",
"db_id": "Q97FP8"
},
{
"db_name": "UniProt",
"db_id": "Q97NG0"
},
{
"db_name": "UniProt",
"db_id": "Q97WE5"
},
{
"db_name": "UniProt",
"db_id": "Q98BV5"
},
{
"db_name": "UniProt",
"db_id": "Q98R79"
},
{
"db_name": "UniProt",
"db_id": "Q9A1L1"
},
{
"db_name": "UniProt",
"db_id": "Q9ABK5"
},
{
"db_name": "UniProt",
"db_id": "Q9CD75"
},
{
"db_name": "UniProt",
"db_id": "Q9CNL2"
},
{
"db_name": "UniProt",
"db_id": "Q9FXM4"
},
{
"db_name": "UniProt",
"db_id": "Q9FXM5"
},
{
"db_name": "UniProt",
"db_id": "Q9HGZ2"
},
{
"db_name": "UniProt",
"db_id": "Q9HIC2"
},
{
"db_name": "UniProt",
"db_id": "Q9HNQ6"
},
{
"db_name": "UniProt",
"db_id": "Q9HV67"
},
{
"db_name": "UniProt",
"db_id": "Q9K7L8"
},
{
"db_name": "UniProt",
"db_id": "Q9KUY4"
},
{
"db_name": "UniProt",
"db_id": "Q9KX58"
},
{
"db_name": "UniProt",
"db_id": "Q9N1E2"
},
{
"db_name": "UniProt",
"db_id": "Q9PGR6"
},
{
"db_name": "UniProt",
"db_id": "Q9PK16"
},
{
"db_name": "UniProt",
"db_id": "Q9PMD4"
},
{
"db_name": "UniProt",
"db_id": "Q9RDY2"
},
{
"db_name": "UniProt",
"db_id": "Q9RMC1"
},
{
"db_name": "UniProt",
"db_id": "Q9RTL8"
},
{
"db_name": "UniProt",
"db_id": "Q9UXW3"
},
{
"db_name": "UniProt",
"db_id": "Q9X1A5"
},
{
"db_name": "UniProt",
"db_id": "Q9X670"
},
{
"db_name": "UniProt",
"db_id": "Q9YE01"
},
{
"db_name": "UniProt",
"db_id": "Q9Z6N4"
},
{
"db_name": "UniProt",
"db_id": "Q9ZK49"
}
]
},
{
"id": "DS.d762.s3.e2",
"type": "compound",
"text": [
"xylitol"
],
"offsets": [
[
840,
847
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6912"
}
]
},
{
"id": "DS.d762.s3.e4",
"type": "protein",
"text": [
"sthA"
],
"offsets": [
[
924,
928
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O05139"
},
{
"db_name": "UniProt",
"db_id": "P27306"
},
{
"db_name": "UniProt",
"db_id": "P50529"
},
{
"db_name": "UniProt",
"db_id": "P57112"
},
{
"db_name": "UniProt",
"db_id": "P66006"
},
{
"db_name": "UniProt",
"db_id": "P66007"
},
{
"db_name": "UniProt",
"db_id": "P66008"
},
{
"db_name": "UniProt",
"db_id": "P66009"
},
{
"db_name": "UniProt",
"db_id": "P71317"
},
{
"db_name": "UniProt",
"db_id": "Q0TA96"
},
{
"db_name": "UniProt",
"db_id": "Q1CBU5"
},
{
"db_name": "UniProt",
"db_id": "Q1CNP4"
},
{
"db_name": "UniProt",
"db_id": "Q1QX78"
},
{
"db_name": "UniProt",
"db_id": "Q1R3U7"
},
{
"db_name": "UniProt",
"db_id": "Q2NQZ3"
},
{
"db_name": "UniProt",
"db_id": "Q2SIP2"
},
{
"db_name": "UniProt",
"db_id": "Q3K9F5"
},
{
"db_name": "UniProt",
"db_id": "Q48A14"
},
{
"db_name": "UniProt",
"db_id": "Q48KI8"
},
{
"db_name": "UniProt",
"db_id": "Q4KFA6"
},
{
"db_name": "UniProt",
"db_id": "Q4ZV77"
},
{
"db_name": "UniProt",
"db_id": "Q57H91"
},
{
"db_name": "UniProt",
"db_id": "Q5E212"
},
{
"db_name": "UniProt",
"db_id": "Q5PK71"
},
{
"db_name": "UniProt",
"db_id": "Q66G61"
},
{
"db_name": "UniProt",
"db_id": "Q6CZB1"
},
{
"db_name": "UniProt",
"db_id": "Q6LLT9"
},
{
"db_name": "UniProt",
"db_id": "Q7MBG9"
},
{
"db_name": "UniProt",
"db_id": "Q7MQ83"
},
{
"db_name": "UniProt",
"db_id": "Q83MI1"
},
{
"db_name": "UniProt",
"db_id": "Q87KN5"
},
{
"db_name": "UniProt",
"db_id": "Q884I6"
},
{
"db_name": "UniProt",
"db_id": "Q88KY8"
},
{
"db_name": "UniProt",
"db_id": "Q8DD46"
},
{
"db_name": "UniProt",
"db_id": "Q8FB93"
},
{
"db_name": "UniProt",
"db_id": "Q8X727"
},
{
"db_name": "UniProt",
"db_id": "Q8ZA97"
},
{
"db_name": "UniProt",
"db_id": "Q9XBQ9"
}
]
},
{
"id": "DS.d762.s3.e5",
"type": "protein",
"text": [
"pntA"
],
"offsets": [
[
933,
937
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P07001"
},
{
"db_name": "UniProt",
"db_id": "P43842"
}
]
},
{
"id": "DS.d762.s4.e0",
"type": "protein",
"text": [
"zwf"
],
"offsets": [
[
1004,
1007
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O51581"
},
{
"db_name": "UniProt",
"db_id": "O54537"
},
{
"db_name": "UniProt",
"db_id": "O68282"
},
{
"db_name": "UniProt",
"db_id": "O83491"
},
{
"db_name": "UniProt",
"db_id": "O84188"
},
{
"db_name": "UniProt",
"db_id": "P0A584"
},
{
"db_name": "UniProt",
"db_id": "P0A585"
},
{
"db_name": "UniProt",
"db_id": "P0A586"
},
{
"db_name": "UniProt",
"db_id": "P0A587"
},
{
"db_name": "UniProt",
"db_id": "P0AC53"
},
{
"db_name": "UniProt",
"db_id": "P0AC54"
},
{
"db_name": "UniProt",
"db_id": "P11411"
},
{
"db_name": "UniProt",
"db_id": "P21907"
},
{
"db_name": "UniProt",
"db_id": "P29686"
},
{
"db_name": "UniProt",
"db_id": "P37986"
},
{
"db_name": "UniProt",
"db_id": "P44311"
},
{
"db_name": "UniProt",
"db_id": "P48848"
},
{
"db_name": "UniProt",
"db_id": "P48992"
},
{
"db_name": "UniProt",
"db_id": "P54547"
},
{
"db_name": "UniProt",
"db_id": "P56110"
},
{
"db_name": "UniProt",
"db_id": "P57405"
},
{
"db_name": "UniProt",
"db_id": "P73411"
},
{
"db_name": "UniProt",
"db_id": "P77809"
},
{
"db_name": "UniProt",
"db_id": "Q89AI7"
},
{
"db_name": "UniProt",
"db_id": "Q8K9M2"
},
{
"db_name": "UniProt",
"db_id": "Q8XCJ6"
},
{
"db_name": "UniProt",
"db_id": "Q9PKK8"
},
{
"db_name": "UniProt",
"db_id": "Q9X0N9"
},
{
"db_name": "UniProt",
"db_id": "Q9Z3S2"
},
{
"db_name": "UniProt",
"db_id": "Q9Z8U6"
},
{
"db_name": "UniProt",
"db_id": "Q9ZKB2"
}
]
},
{
"id": "DS.d762.s4.e1",
"type": "protein",
"text": [
"sucC"
],
"offsets": [
[
1011,
1015
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O05966"
},
{
"db_name": "UniProt",
"db_id": "O27115"
},
{
"db_name": "UniProt",
"db_id": "O67546"
},
{
"db_name": "UniProt",
"db_id": "O84828"
},
{
"db_name": "UniProt",
"db_id": "O87840"
},
{
"db_name": "UniProt",
"db_id": "P0A836"
},
{
"db_name": "UniProt",
"db_id": "P0A837"
},
{
"db_name": "UniProt",
"db_id": "P0A838"
},
{
"db_name": "UniProt",
"db_id": "P0A839"
},
{
"db_name": "UniProt",
"db_id": "P25126"
},
{
"db_name": "UniProt",
"db_id": "P45101"
},
{
"db_name": "UniProt",
"db_id": "P53592"
},
{
"db_name": "UniProt",
"db_id": "P53593"
},
{
"db_name": "UniProt",
"db_id": "P66867"
},
{
"db_name": "UniProt",
"db_id": "P66868"
},
{
"db_name": "UniProt",
"db_id": "P66869"
},
{
"db_name": "UniProt",
"db_id": "P66870"
},
{
"db_name": "UniProt",
"db_id": "P66871"
},
{
"db_name": "UniProt",
"db_id": "P66872"
},
{
"db_name": "UniProt",
"db_id": "P71559"
},
{
"db_name": "UniProt",
"db_id": "P80886"
},
{
"db_name": "UniProt",
"db_id": "P99071"
},
{
"db_name": "UniProt",
"db_id": "Q49X32"
},
{
"db_name": "UniProt",
"db_id": "Q4L5U8"
},
{
"db_name": "UniProt",
"db_id": "Q4ULQ7"
},
{
"db_name": "UniProt",
"db_id": "Q57663"
},
{
"db_name": "UniProt",
"db_id": "Q57RL3"
},
{
"db_name": "UniProt",
"db_id": "Q5HGI7"
},
{
"db_name": "UniProt",
"db_id": "Q5HPU5"
},
{
"db_name": "UniProt",
"db_id": "Q5PBI8"
},
{
"db_name": "UniProt",
"db_id": "Q5PCM7"
},
{
"db_name": "UniProt",
"db_id": "Q66DA0"
},
{
"db_name": "UniProt",
"db_id": "Q68WU5"
},
{
"db_name": "UniProt",
"db_id": "Q6F8L4"
},
{
"db_name": "UniProt",
"db_id": "Q6G9W8"
},
{
"db_name": "UniProt",
"db_id": "Q6GHJ0"
},
{
"db_name": "UniProt",
"db_id": "Q72PA2"
},
{
"db_name": "UniProt",
"db_id": "Q7MMN3"
},
{
"db_name": "UniProt",
"db_id": "Q7U0Z1"
},
{
"db_name": "UniProt",
"db_id": "Q7UKI3"
},
{
"db_name": "UniProt",
"db_id": "Q822A1"
},
{
"db_name": "UniProt",
"db_id": "Q87A98"
},
{
"db_name": "UniProt",
"db_id": "Q87RE8"
},
{
"db_name": "UniProt",
"db_id": "Q8CPH5"
},
{
"db_name": "UniProt",
"db_id": "Q8DFQ1"
},
{
"db_name": "UniProt",
"db_id": "Q8EFN8"
},
{
"db_name": "UniProt",
"db_id": "Q8F746"
},
{
"db_name": "UniProt",
"db_id": "Q8KFE7"
},
{
"db_name": "UniProt",
"db_id": "Q8NMK7"
},
{
"db_name": "UniProt",
"db_id": "Q8P676"
},
{
"db_name": "UniProt",
"db_id": "Q8PHL5"
},
{
"db_name": "UniProt",
"db_id": "Q8UC60"
},
{
"db_name": "UniProt",
"db_id": "Q8Y1Y3"
},
{
"db_name": "UniProt",
"db_id": "Q8ZH00"
},
{
"db_name": "UniProt",
"db_id": "Q8ZVF3"
},
{
"db_name": "UniProt",
"db_id": "Q92I21"
},
{
"db_name": "UniProt",
"db_id": "Q98EC5"
},
{
"db_name": "UniProt",
"db_id": "Q9AB94"
},
{
"db_name": "UniProt",
"db_id": "Q9CNZ0"
},
{
"db_name": "UniProt",
"db_id": "Q9EYG9"
},
{
"db_name": "UniProt",
"db_id": "Q9HPP1"
},
{
"db_name": "UniProt",
"db_id": "Q9JUT0"
},
{
"db_name": "UniProt",
"db_id": "Q9JZP4"
},
{
"db_name": "UniProt",
"db_id": "Q9KA20"
},
{
"db_name": "UniProt",
"db_id": "Q9KQB5"
},
{
"db_name": "UniProt",
"db_id": "Q9PAH1"
},
{
"db_name": "UniProt",
"db_id": "Q9PHY1"
},
{
"db_name": "UniProt",
"db_id": "Q9PL99"
},
{
"db_name": "UniProt",
"db_id": "Q9RUY3"
},
{
"db_name": "UniProt",
"db_id": "Q9Z5H8"
},
{
"db_name": "UniProt",
"db_id": "Q9Z6T6"
}
]
},
{
"id": "DS.d762.s4.e2",
"type": "compound",
"text": [
"xylitol"
],
"offsets": [
[
1088,
1095
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6912"
}
]
},
{
"id": "DS.d762.s4.e3",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
1101,
1108
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
}
] | [] | [] | [
{
"id": "DS.d762.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s0.e1",
"arg2_id": "DS.d762.s0.e0",
"normalized": []
},
{
"id": "DS.d762.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s0.e2",
"arg2_id": "DS.d762.s0.e0",
"normalized": []
},
{
"id": "DS.d762.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s1.e1",
"arg2_id": "DS.d762.s1.e0",
"normalized": []
},
{
"id": "DS.d762.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s2.e2",
"arg2_id": "DS.d762.s2.e0",
"normalized": []
},
{
"id": "DS.d762.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s2.e2",
"arg2_id": "DS.d762.s2.e1",
"normalized": []
},
{
"id": "DS.d762.s3.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s3.e2",
"arg2_id": "DS.d762.s3.e1",
"normalized": []
},
{
"id": "DS.d762.s3.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s3.e2",
"arg2_id": "DS.d762.s3.e0",
"normalized": []
},
{
"id": "DS.d762.s4.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s4.e3",
"arg2_id": "DS.d762.s4.e0",
"normalized": []
},
{
"id": "DS.d762.s4.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s4.e2",
"arg2_id": "DS.d762.s4.e1",
"normalized": []
},
{
"id": "DS.d762.s4.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s4.e3",
"arg2_id": "DS.d762.s4.e1",
"normalized": []
},
{
"id": "DS.d762.s4.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d762.s4.e2",
"arg2_id": "DS.d762.s4.e0",
"normalized": []
}
] |
DS.d763 | 18698649 | [
{
"id": "DS.d763.s0",
"type": "",
"text": [
"In the process studied, the enzyme cellobiose dehydrogenase (CDH) oxidizes lactose at the C-1 position of the reducing sugar moiety to lactobionolactone, which spontaneously hydrolyzes to lactobionic acid."
],
"offsets": [
[
0,
205
]
]
},
{
"id": "DS.d763.s2",
"type": "",
"text": [
"Oxygen served as the terminal electron acceptor of the reaction and was fully reduced to water by laccase."
],
"offsets": [
[
206,
312
]
]
}
] | [
{
"id": "DS.d763.s0.e0",
"type": "protein",
"text": [
"CDH"
],
"offsets": [
[
61,
64
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P17444"
},
{
"db_name": "UniProt",
"db_id": "P54223"
},
{
"db_name": "UniProt",
"db_id": "P60336"
},
{
"db_name": "UniProt",
"db_id": "P60337"
},
{
"db_name": "UniProt",
"db_id": "Q01738"
},
{
"db_name": "UniProt",
"db_id": "Q0TKW1"
},
{
"db_name": "UniProt",
"db_id": "Q13NG7"
},
{
"db_name": "UniProt",
"db_id": "Q1BQE2"
},
{
"db_name": "UniProt",
"db_id": "Q1C932"
},
{
"db_name": "UniProt",
"db_id": "Q1CFR7"
},
{
"db_name": "UniProt",
"db_id": "Q1MJU4"
},
{
"db_name": "UniProt",
"db_id": "Q1QXE1"
},
{
"db_name": "UniProt",
"db_id": "Q1RFM3"
},
{
"db_name": "UniProt",
"db_id": "Q2FDP9"
},
{
"db_name": "UniProt",
"db_id": "Q2FV11"
},
{
"db_name": "UniProt",
"db_id": "Q2KB43"
},
{
"db_name": "UniProt",
"db_id": "Q2T6D0"
},
{
"db_name": "UniProt",
"db_id": "Q2YWJ5"
},
{
"db_name": "UniProt",
"db_id": "Q39A44"
},
{
"db_name": "UniProt",
"db_id": "Q3BXK8"
},
{
"db_name": "UniProt",
"db_id": "Q3JLL7"
},
{
"db_name": "UniProt",
"db_id": "Q3K5H3"
},
{
"db_name": "UniProt",
"db_id": "Q48CM7"
},
{
"db_name": "UniProt",
"db_id": "Q4A0Q1"
},
{
"db_name": "UniProt",
"db_id": "Q4K4K7"
},
{
"db_name": "UniProt",
"db_id": "Q4L9D7"
},
{
"db_name": "UniProt",
"db_id": "Q4UYN5"
},
{
"db_name": "UniProt",
"db_id": "Q4ZM63"
},
{
"db_name": "UniProt",
"db_id": "Q5HCU1"
},
{
"db_name": "UniProt",
"db_id": "Q5HL11"
},
{
"db_name": "UniProt",
"db_id": "Q62CH8"
},
{
"db_name": "UniProt",
"db_id": "Q63KK7"
},
{
"db_name": "UniProt",
"db_id": "Q66D54"
},
{
"db_name": "UniProt",
"db_id": "Q6D6D9"
},
{
"db_name": "UniProt",
"db_id": "Q6FDF9"
},
{
"db_name": "UniProt",
"db_id": "Q6G664"
},
{
"db_name": "UniProt",
"db_id": "Q6GDJ1"
},
{
"db_name": "UniProt",
"db_id": "Q6LGH5"
},
{
"db_name": "UniProt",
"db_id": "Q7MF12"
},
{
"db_name": "UniProt",
"db_id": "Q88AE7"
},
{
"db_name": "UniProt",
"db_id": "Q88CW6"
},
{
"db_name": "UniProt",
"db_id": "Q8BJ64"
},
{
"db_name": "UniProt",
"db_id": "Q8CMY2"
},
{
"db_name": "UniProt",
"db_id": "Q8D3K2"
},
{
"db_name": "UniProt",
"db_id": "Q8FKI9"
},
{
"db_name": "UniProt",
"db_id": "Q8G1Z8"
},
{
"db_name": "UniProt",
"db_id": "Q8NE62"
},
{
"db_name": "UniProt",
"db_id": "Q8NUM0"
},
{
"db_name": "UniProt",
"db_id": "Q8P5D7"
},
{
"db_name": "UniProt",
"db_id": "Q8PPG8"
},
{
"db_name": "UniProt",
"db_id": "Q8UH55"
},
{
"db_name": "UniProt",
"db_id": "Q8X6C6"
},
{
"db_name": "UniProt",
"db_id": "Q8YFY2"
},
{
"db_name": "UniProt",
"db_id": "Q8ZGW0"
},
{
"db_name": "UniProt",
"db_id": "Q985M5"
},
{
"db_name": "UniProt",
"db_id": "Q9HTJ2"
},
{
"db_name": "UniProt",
"db_id": "Q9L4K0"
},
{
"db_name": "UniProt",
"db_id": "Q9RA05"
},
{
"db_name": "UniProt",
"db_id": "Q9X2M2"
}
]
},
{
"id": "DS.d763.s0.e1",
"type": "compound",
"text": [
"lactose"
],
"offsets": [
[
75,
82
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "294"
},
{
"db_name": "PubChem",
"db_id": "6134"
},
{
"db_name": "PubChem",
"db_id": "84571"
},
{
"db_name": "PubChem",
"db_id": "440995"
}
]
},
{
"id": "DS.d763.s0.e2",
"type": "compound",
"text": [
"lactobionic acid"
],
"offsets": [
[
188,
204
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "7314"
}
]
},
{
"id": "DS.d763.s2.e0",
"type": "compound",
"text": [
"Oxygen"
],
"offsets": [
[
206,
212
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "977"
}
]
},
{
"id": "DS.d763.s2.e1",
"type": "protein",
"text": [
"laccase"
],
"offsets": [
[
304,
311
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q12570"
}
]
}
] | [] | [] | [
{
"id": "DS.d763.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d763.s0.e2",
"arg2_id": "DS.d763.s0.e0",
"normalized": []
},
{
"id": "DS.d763.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d763.s0.e1",
"arg2_id": "DS.d763.s0.e0",
"normalized": []
},
{
"id": "DS.d763.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d763.s2.e0",
"arg2_id": "DS.d763.s2.e1",
"normalized": []
}
] |
DS.d764 | 18699724 | [
{
"id": "DS.d764.s0",
"type": "",
"text": [
"Immunocytochemical localization of cell surface markers like SSEA-3, SSEA-4, TRA-1-60, and TRA-1-81, staining for alkaline phosphatase and reverse transcriptase polymerase chain reaction (RT-PCR) analysis of pluripotency state markers viz."
],
"offsets": [
[
0,
239
]
]
}
] | [
{
"id": "DS.d764.s0.e0",
"type": "compound",
"text": [
"SSEA-3"
],
"offsets": [
[
61,
67
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "53262342"
}
]
},
{
"id": "DS.d764.s0.e1",
"type": "compound",
"text": [
"TRA"
],
"offsets": [
[
77,
80
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "444212"
}
]
},
{
"id": "DS.d764.s0.e2",
"type": "compound",
"text": [
"TRA"
],
"offsets": [
[
91,
94
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "444212"
}
]
},
{
"id": "DS.d764.s0.e3",
"type": "protein",
"text": [
"alkaline phosphatase"
],
"offsets": [
[
114,
134
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O60109"
},
{
"db_name": "UniProt",
"db_id": "P81800"
},
{
"db_name": "UniProt",
"db_id": "P83456"
}
]
},
{
"id": "DS.d764.s0.e4",
"type": "protein",
"text": [
"reverse transcriptase"
],
"offsets": [
[
139,
160
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P03358"
},
{
"db_name": "UniProt",
"db_id": "P03554"
},
{
"db_name": "UniProt",
"db_id": "P03555"
},
{
"db_name": "UniProt",
"db_id": "P03556"
},
{
"db_name": "UniProt",
"db_id": "P04323"
},
{
"db_name": "UniProt",
"db_id": "P05400"
},
{
"db_name": "UniProt",
"db_id": "P09523"
},
{
"db_name": "UniProt",
"db_id": "P0A3U0"
},
{
"db_name": "UniProt",
"db_id": "P0A3U1"
},
{
"db_name": "UniProt",
"db_id": "P10394"
},
{
"db_name": "UniProt",
"db_id": "P10399"
},
{
"db_name": "UniProt",
"db_id": "P10400"
},
{
"db_name": "UniProt",
"db_id": "P10401"
},
{
"db_name": "UniProt",
"db_id": "P10978"
},
{
"db_name": "UniProt",
"db_id": "P11283"
},
{
"db_name": "UniProt",
"db_id": "P11369"
},
{
"db_name": "UniProt",
"db_id": "P15629"
},
{
"db_name": "UniProt",
"db_id": "P16423"
},
{
"db_name": "UniProt",
"db_id": "P19199"
},
{
"db_name": "UniProt",
"db_id": "P20825"
},
{
"db_name": "UniProt",
"db_id": "P21325"
},
{
"db_name": "UniProt",
"db_id": "P21328"
},
{
"db_name": "UniProt",
"db_id": "P21329"
},
{
"db_name": "UniProt",
"db_id": "P23070"
},
{
"db_name": "UniProt",
"db_id": "P23071"
},
{
"db_name": "UniProt",
"db_id": "P23072"
},
{
"db_name": "UniProt",
"db_id": "P27502"
},
{
"db_name": "UniProt",
"db_id": "Q00962"
},
{
"db_name": "UniProt",
"db_id": "Q02964"
},
{
"db_name": "UniProt",
"db_id": "Q03269"
},
{
"db_name": "UniProt",
"db_id": "Q03270"
},
{
"db_name": "UniProt",
"db_id": "Q03271"
},
{
"db_name": "UniProt",
"db_id": "Q03272"
},
{
"db_name": "UniProt",
"db_id": "Q03273"
},
{
"db_name": "UniProt",
"db_id": "Q03274"
},
{
"db_name": "UniProt",
"db_id": "Q03275"
},
{
"db_name": "UniProt",
"db_id": "Q03276"
},
{
"db_name": "UniProt",
"db_id": "Q03277"
},
{
"db_name": "UniProt",
"db_id": "Q03278"
},
{
"db_name": "UniProt",
"db_id": "Q03279"
},
{
"db_name": "UniProt",
"db_id": "Q05118"
},
{
"db_name": "UniProt",
"db_id": "Q8I7P9"
},
{
"db_name": "UniProt",
"db_id": "Q95SX7"
},
{
"db_name": "UniProt",
"db_id": "Q9NBX4"
},
{
"db_name": "UniProt",
"db_id": "Q9QC07"
}
]
},
{
"id": "DS.d764.s0.e5",
"type": "protein",
"text": [
"PCR"
],
"offsets": [
[
191,
194
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O66148"
},
{
"db_name": "UniProt",
"db_id": "O80333"
},
{
"db_name": "UniProt",
"db_id": "P15904"
},
{
"db_name": "UniProt",
"db_id": "Q01289"
},
{
"db_name": "UniProt",
"db_id": "Q39617"
},
{
"db_name": "UniProt",
"db_id": "Q41249"
},
{
"db_name": "UniProt",
"db_id": "Q59987"
},
{
"db_name": "UniProt",
"db_id": "Q9SDT1"
}
]
}
] | [] | [] | [] |
DS.d765 | 18699774 | [
{
"id": "DS.d765.s0",
"type": "",
"text": [
"Solamargine induces apoptosis and enhances susceptibility to trastuzumab and epirubicin in breast cancer cells with low or high expression levels of HER2/neu."
],
"offsets": [
[
0,
158
]
]
},
{
"id": "DS.d765.s1",
"type": "",
"text": [
"SM (solamargine), a major steroidal alkaloid glycoside purified from Solanum incanum, triggered apoptosis of breast cancer cells (MCF-7 and SK-BR-3 cells) and non-cancerous breast epithelial cells (HBL-100 cells) within 3 h. To extend the application of trastuzumab in breast cancer patients, the regulation of HER2/neu expression by SM was investigated."
],
"offsets": [
[
159,
513
]
]
}
] | [
{
"id": "DS.d765.s0.e0",
"type": "compound",
"text": [
"Solamargine"
],
"offsets": [
[
0,
11
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "73611"
}
]
},
{
"id": "DS.d765.s0.e1",
"type": "compound",
"text": [
"epirubicin"
],
"offsets": [
[
77,
87
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "41867"
}
]
},
{
"id": "DS.d765.s0.e2",
"type": "protein",
"text": [
"HER2"
],
"offsets": [
[
149,
153
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P04626"
}
]
},
{
"id": "DS.d765.s0.e3",
"type": "protein",
"text": [
"neu"
],
"offsets": [
[
154,
157
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35657"
},
{
"db_name": "UniProt",
"db_id": "P06494"
},
{
"db_name": "UniProt",
"db_id": "P29503"
},
{
"db_name": "UniProt",
"db_id": "P70424"
},
{
"db_name": "UniProt",
"db_id": "Q24746"
}
]
},
{
"id": "DS.d765.s1.e0",
"type": "compound",
"text": [
"solamargine"
],
"offsets": [
[
163,
174
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "73611"
}
]
},
{
"id": "DS.d765.s1.e1",
"type": "compound",
"text": [
"steroidal alkaloid"
],
"offsets": [
[
185,
203
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "452975"
}
]
},
{
"id": "DS.d765.s1.e2",
"type": "protein",
"text": [
"HER2"
],
"offsets": [
[
470,
474
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P04626"
}
]
},
{
"id": "DS.d765.s1.e3",
"type": "protein",
"text": [
"neu"
],
"offsets": [
[
475,
478
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35657"
},
{
"db_name": "UniProt",
"db_id": "P06494"
},
{
"db_name": "UniProt",
"db_id": "P29503"
},
{
"db_name": "UniProt",
"db_id": "P70424"
},
{
"db_name": "UniProt",
"db_id": "Q24746"
}
]
}
] | [] | [] | [] |
DS.d766 | 18700056 | [
{
"id": "DS.d766.s0",
"type": "",
"text": [
"Since ondansetron completely reversed the effects of clorgyline on DA neuronal activity, the effects of MAOA inhibition appeared to be mediated by 5-HT3 receptors."
],
"offsets": [
[
0,
163
]
]
}
] | [
{
"id": "DS.d766.s0.e0",
"type": "compound",
"text": [
"ondansetron"
],
"offsets": [
[
6,
17
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4595"
}
]
},
{
"id": "DS.d766.s0.e1",
"type": "compound",
"text": [
"clorgyline"
],
"offsets": [
[
53,
63
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4380"
}
]
},
{
"id": "DS.d766.s0.e2",
"type": "protein",
"text": [
"MAOA"
],
"offsets": [
[
104,
108
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18851"
},
{
"db_name": "UniProt",
"db_id": "P21397"
},
{
"db_name": "UniProt",
"db_id": "P21398"
},
{
"db_name": "UniProt",
"db_id": "P58027"
},
{
"db_name": "UniProt",
"db_id": "Q5NU32"
},
{
"db_name": "UniProt",
"db_id": "Q5RE60"
},
{
"db_name": "UniProt",
"db_id": "Q6Q2J0"
}
]
},
{
"id": "DS.d766.s0.e3",
"type": "protein",
"text": [
"5-HT3"
],
"offsets": [
[
147,
152
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O70212"
},
{
"db_name": "UniProt",
"db_id": "P23979"
},
{
"db_name": "UniProt",
"db_id": "P35563"
},
{
"db_name": "UniProt",
"db_id": "P46098"
}
]
}
] | [] | [] | [] |
DS.d767 | 18700057 | [
{
"id": "DS.d767.s0",
"type": "",
"text": [
"The effects of Ipt were reversed by the mitochondrial KATP blocker, 5-hydroxydecanoate, indicating that mitochondrial KATP channels participate in the regulation of astrocyte activation."
],
"offsets": [
[
0,
186
]
]
}
] | [
{
"id": "DS.d767.s0.e0",
"type": "protein",
"text": [
"Ipt"
],
"offsets": [
[
15,
18
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0A3L5"
},
{
"db_name": "UniProt",
"db_id": "P0A3L6"
},
{
"db_name": "UniProt",
"db_id": "P15653"
},
{
"db_name": "UniProt",
"db_id": "P25018"
},
{
"db_name": "UniProt",
"db_id": "P46376"
},
{
"db_name": "UniProt",
"db_id": "Q04590"
},
{
"db_name": "UniProt",
"db_id": "Q47851"
},
{
"db_name": "UniProt",
"db_id": "Q80UN9"
}
]
},
{
"id": "DS.d767.s0.e1",
"type": "compound",
"text": [
"5-hydroxydecanoate"
],
"offsets": [
[
68,
86
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1825"
}
]
}
] | [] | [] | [
{
"id": "DS.d767.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d767.s0.e1",
"arg2_id": "DS.d767.s0.e0",
"normalized": []
}
] |
DS.d768 | 18700809 | [
{
"id": "DS.d768.s0",
"type": "",
"text": [
"The cell proliferation, the up-regulation of pS2, and the down-regulation of ERalpha and ERbeta gene expressions induced by the racemate and enantiomers of o,p'-DDT were all reversed by cotreatment with 10(-6) mol/L ICI 182,780."
],
"offsets": [
[
0,
228
]
]
}
] | [
{
"id": "DS.d768.s0.e0",
"type": "protein",
"text": [
"ERalpha"
],
"offsets": [
[
77,
84
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O42132"
},
{
"db_name": "UniProt",
"db_id": "P03372"
},
{
"db_name": "UniProt",
"db_id": "P06211"
},
{
"db_name": "UniProt",
"db_id": "P06212"
},
{
"db_name": "UniProt",
"db_id": "P16058"
},
{
"db_name": "UniProt",
"db_id": "P19785"
},
{
"db_name": "UniProt",
"db_id": "P49884"
},
{
"db_name": "UniProt",
"db_id": "P49885"
},
{
"db_name": "UniProt",
"db_id": "P49886"
},
{
"db_name": "UniProt",
"db_id": "P50240"
},
{
"db_name": "UniProt",
"db_id": "P50241"
},
{
"db_name": "UniProt",
"db_id": "P50242"
},
{
"db_name": "UniProt",
"db_id": "P57717"
},
{
"db_name": "UniProt",
"db_id": "P57753"
},
{
"db_name": "UniProt",
"db_id": "P81559"
},
{
"db_name": "UniProt",
"db_id": "Q29040"
},
{
"db_name": "UniProt",
"db_id": "Q53AD2"
},
{
"db_name": "UniProt",
"db_id": "Q91250"
},
{
"db_name": "UniProt",
"db_id": "Q91424"
},
{
"db_name": "UniProt",
"db_id": "Q9PVZ9"
},
{
"db_name": "UniProt",
"db_id": "Q9QZJ5"
},
{
"db_name": "UniProt",
"db_id": "Q9TV98"
},
{
"db_name": "UniProt",
"db_id": "Q9YH33"
},
{
"db_name": "UniProt",
"db_id": "Q9YHT3"
},
{
"db_name": "UniProt",
"db_id": "Q9YHZ7"
}
]
},
{
"id": "DS.d768.s0.e1",
"type": "protein",
"text": [
"ERbeta"
],
"offsets": [
[
89,
95
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O08537"
},
{
"db_name": "UniProt",
"db_id": "O13012"
},
{
"db_name": "UniProt",
"db_id": "O93511"
},
{
"db_name": "UniProt",
"db_id": "P57781"
},
{
"db_name": "UniProt",
"db_id": "P57782"
},
{
"db_name": "UniProt",
"db_id": "Q62986"
},
{
"db_name": "UniProt",
"db_id": "Q92731"
},
{
"db_name": "UniProt",
"db_id": "Q95171"
},
{
"db_name": "UniProt",
"db_id": "Q9IAK1"
},
{
"db_name": "UniProt",
"db_id": "Q9PTU5"
},
{
"db_name": "UniProt",
"db_id": "Q9PVE2"
},
{
"db_name": "UniProt",
"db_id": "Q9TTE5"
},
{
"db_name": "UniProt",
"db_id": "Q9TU15"
},
{
"db_name": "UniProt",
"db_id": "Q9W6M2"
},
{
"db_name": "UniProt",
"db_id": "Q9XSB5"
},
{
"db_name": "UniProt",
"db_id": "Q9XSW2"
},
{
"db_name": "UniProt",
"db_id": "Q9YH32"
}
]
},
{
"id": "DS.d768.s0.e2",
"type": "compound",
"text": [
"ICI 182,780"
],
"offsets": [
[
216,
227
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "104741"
}
]
}
] | [] | [] | [
{
"id": "DS.d768.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d768.s0.e2",
"arg2_id": "DS.d768.s0.e0",
"normalized": []
},
{
"id": "DS.d768.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d768.s0.e2",
"arg2_id": "DS.d768.s0.e1",
"normalized": []
}
] |
DS.d769 | 18700818 | [
{
"id": "DS.d769.s0",
"type": "",
"text": [
"While bass in all diazinon treatment groups had significantly inhibited brain AChE activity, only the medium and high treatment groups showed a dose- and time-dependent increase in time to capture prey."
],
"offsets": [
[
0,
202
]
]
}
] | [
{
"id": "DS.d769.s0.e0",
"type": "compound",
"text": [
"diazinon"
],
"offsets": [
[
18,
26
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3017"
}
]
},
{
"id": "DS.d769.s0.e1",
"type": "protein",
"text": [
"AChE"
],
"offsets": [
[
78,
82
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O42275"
},
{
"db_name": "UniProt",
"db_id": "O62763"
},
{
"db_name": "UniProt",
"db_id": "P04058"
},
{
"db_name": "UniProt",
"db_id": "P07140"
},
{
"db_name": "UniProt",
"db_id": "P07692"
},
{
"db_name": "UniProt",
"db_id": "P21836"
},
{
"db_name": "UniProt",
"db_id": "P22303"
},
{
"db_name": "UniProt",
"db_id": "P23795"
},
{
"db_name": "UniProt",
"db_id": "P36196"
},
{
"db_name": "UniProt",
"db_id": "P37136"
},
{
"db_name": "UniProt",
"db_id": "P56161"
},
{
"db_name": "UniProt",
"db_id": "Q27677"
},
{
"db_name": "UniProt",
"db_id": "Q29499"
},
{
"db_name": "UniProt",
"db_id": "Q867X2"
},
{
"db_name": "UniProt",
"db_id": "Q867X3"
},
{
"db_name": "UniProt",
"db_id": "Q869C3"
},
{
"db_name": "UniProt",
"db_id": "Q86GC8"
},
{
"db_name": "UniProt",
"db_id": "Q86GC9"
},
{
"db_name": "UniProt",
"db_id": "Q92035"
},
{
"db_name": "UniProt",
"db_id": "Q92081"
},
{
"db_name": "UniProt",
"db_id": "Q9DDE3"
}
]
}
] | [] | [] | [
{
"id": "DS.d769.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d769.s0.e0",
"arg2_id": "DS.d769.s0.e1",
"normalized": []
}
] |
DS.d770 | 18701427 | [
{
"id": "DS.d770.s0",
"type": "",
"text": [
"The aim of this phase 0 study was to investigate whether gemcitabine passes the blood-tumor barrier, and is phosphorylated in the tumor by deoxycytidine kinase (dCK) to gemcitabine nucleotides in order to enable radiosensitization, and whether it is deaminated by deoxycytidine deaminase (dCDA) to dFdU."
],
"offsets": [
[
0,
303
]
]
}
] | [
{
"id": "DS.d770.s0.e0",
"type": "compound",
"text": [
"gemcitabine"
],
"offsets": [
[
57,
68
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "60750"
}
]
},
{
"id": "DS.d770.s0.e1",
"type": "protein",
"text": [
"deoxycytidine kinase"
],
"offsets": [
[
139,
159
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P27707"
},
{
"db_name": "UniProt",
"db_id": "P43346"
},
{
"db_name": "UniProt",
"db_id": "P48769"
}
]
},
{
"id": "DS.d770.s0.e2",
"type": "protein",
"text": [
"dCK"
],
"offsets": [
[
161,
164
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P21974"
},
{
"db_name": "UniProt",
"db_id": "P27707"
},
{
"db_name": "UniProt",
"db_id": "P43346"
},
{
"db_name": "UniProt",
"db_id": "P48769"
},
{
"db_name": "UniProt",
"db_id": "Q9J579"
}
]
},
{
"id": "DS.d770.s0.e3",
"type": "compound",
"text": [
"gemcitabine"
],
"offsets": [
[
169,
180
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "60750"
}
]
}
] | [] | [] | [
{
"id": "DS.d770.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d770.s0.e0",
"arg2_id": "DS.d770.s0.e1",
"normalized": []
},
{
"id": "DS.d770.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d770.s0.e0",
"arg2_id": "DS.d770.s0.e2",
"normalized": []
}
] |
DS.d771 | 18701806 | [
{
"id": "DS.d771.s0",
"type": "",
"text": [
"The proline mutation at amino acid location 164 significantly reduced the initial hydrolysis of either the amelogenins in solution or the proteins bound on HAP, which was confirmed by amelogenin oligopeptide assays."
],
"offsets": [
[
0,
215
]
]
}
] | [
{
"id": "DS.d771.s0.e0",
"type": "compound",
"text": [
"proline"
],
"offsets": [
[
4,
11
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "614"
},
{
"db_name": "PubChem",
"db_id": "8988"
},
{
"db_name": "PubChem",
"db_id": "145742"
}
]
},
{
"id": "DS.d771.s0.e1",
"type": "protein",
"text": [
"amelogenins"
],
"offsets": [
[
107,
118
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O97646"
},
{
"db_name": "UniProt",
"db_id": "O97647"
},
{
"db_name": "UniProt",
"db_id": "Q28462"
}
]
}
] | [] | [] | [
{
"id": "DS.d771.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d771.s0.e0",
"arg2_id": "DS.d771.s0.e1",
"normalized": []
}
] |
DS.d772 | 18701809 | [
{
"id": "DS.d772.s0",
"type": "",
"text": [
"In conclusion, dentin mineralization in a corrected phosphate and vitamin D environment compensates the adverse effect of PHEX mutation."
],
"offsets": [
[
0,
136
]
]
}
] | [
{
"id": "DS.d772.s0.e0",
"type": "compound",
"text": [
"phosphate"
],
"offsets": [
[
52,
61
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1061"
},
{
"db_name": "PubChem",
"db_id": "167704"
},
{
"db_name": "PubChem",
"db_id": "644102"
}
]
},
{
"id": "DS.d772.s0.e1",
"type": "compound",
"text": [
"vitamin D"
],
"offsets": [
[
66,
75
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5280795"
}
]
},
{
"id": "DS.d772.s0.e2",
"type": "protein",
"text": [
"PHEX"
],
"offsets": [
[
122,
126
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P78562"
}
]
}
] | [] | [] | [] |
DS.d773 | 18702173 | [
{
"id": "DS.d773.s0",
"type": "",
"text": [
"The considered biological model system consisted of a coating antibody (goat IgG), bovine serum albumin (BSA) as blocking agent, and a complementary antibody labelled with FITC (anti-goat IgG)."
],
"offsets": [
[
0,
193
]
]
}
] | [
{
"id": "DS.d773.s0.e0",
"type": "protein",
"text": [
"serum albumin"
],
"offsets": [
[
90,
103
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P21847"
},
{
"db_name": "UniProt",
"db_id": "P83517"
}
]
},
{
"id": "DS.d773.s0.e1",
"type": "protein",
"text": [
"BSA"
],
"offsets": [
[
105,
108
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P02769"
}
]
},
{
"id": "DS.d773.s0.e2",
"type": "compound",
"text": [
"FITC"
],
"offsets": [
[
172,
176
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "18730"
}
]
}
] | [] | [] | [] |
DS.d774 | 18702613 | [
{
"id": "DS.d774.s0",
"type": "",
"text": [
"Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells."
],
"offsets": [
[
0,
149
]
]
},
{
"id": "DS.d774.s1",
"type": "",
"text": [
"Collectively, these results illustrate the phenomenon of beta-cell desensitization by amino acids, indicating that prolonged exposure to alanine can induce reversible alterations to metabolic flux, Ca(2+) handling and insulin secretion."
],
"offsets": [
[
150,
386
]
]
}
] | [
{
"id": "DS.d774.s0.e0",
"type": "compound",
"text": [
"alanine"
],
"offsets": [
[
12,
19
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "602"
},
{
"db_name": "PubChem",
"db_id": "4580"
},
{
"db_name": "PubChem",
"db_id": "5950"
},
{
"db_name": "PubChem",
"db_id": "71080"
}
]
},
{
"id": "DS.d774.s0.e1",
"type": "compound",
"text": [
"Ca(2"
],
"offsets": [
[
60,
64
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "271"
}
]
},
{
"id": "DS.d774.s0.e2",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
99,
106
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d774.s1.e0",
"type": "compound",
"text": [
"alanine"
],
"offsets": [
[
287,
294
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "602"
},
{
"db_name": "PubChem",
"db_id": "4580"
},
{
"db_name": "PubChem",
"db_id": "5950"
},
{
"db_name": "PubChem",
"db_id": "71080"
}
]
},
{
"id": "DS.d774.s1.e1",
"type": "compound",
"text": [
"Ca(2"
],
"offsets": [
[
348,
352
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "271"
}
]
},
{
"id": "DS.d774.s1.e2",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
368,
375
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
}
] | [] | [] | [
{
"id": "DS.d774.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d774.s0.e0",
"arg2_id": "DS.d774.s0.e2",
"normalized": []
},
{
"id": "DS.d774.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d774.s1.e0",
"arg2_id": "DS.d774.s1.e2",
"normalized": []
}
] |
DS.d775 | 18702682 | [
{
"id": "DS.d775.s0",
"type": "",
"text": [
"Acylation-stimulating protein (ASP) has been shown to positively stimulate fatty acid esterification and glucose uptake in adipocytes."
],
"offsets": [
[
0,
134
]
]
}
] | [
{
"id": "DS.d775.s0.e0",
"type": "protein",
"text": [
"ASP"
],
"offsets": [
[
31,
34
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P32765"
},
{
"db_name": "UniProt",
"db_id": "P42127"
},
{
"db_name": "UniProt",
"db_id": "P45381"
},
{
"db_name": "UniProt",
"db_id": "P79407"
},
{
"db_name": "UniProt",
"db_id": "Q03288"
},
{
"db_name": "UniProt",
"db_id": "Q16937"
},
{
"db_name": "UniProt",
"db_id": "Q1XGU5"
},
{
"db_name": "UniProt",
"db_id": "Q1XGU6"
},
{
"db_name": "UniProt",
"db_id": "Q1XGU7"
},
{
"db_name": "UniProt",
"db_id": "Q1XGU8"
},
{
"db_name": "UniProt",
"db_id": "Q1XGU9"
},
{
"db_name": "UniProt",
"db_id": "Q1XGV0"
},
{
"db_name": "UniProt",
"db_id": "Q1XGV1"
},
{
"db_name": "UniProt",
"db_id": "Q1XGV2"
},
{
"db_name": "UniProt",
"db_id": "Q1XGV3"
},
{
"db_name": "UniProt",
"db_id": "Q1XGV4"
},
{
"db_name": "UniProt",
"db_id": "Q1XGV5"
},
{
"db_name": "UniProt",
"db_id": "Q1XGV6"
},
{
"db_name": "UniProt",
"db_id": "Q1XGV7"
},
{
"db_name": "UniProt",
"db_id": "Q29414"
},
{
"db_name": "UniProt",
"db_id": "Q5UK76"
},
{
"db_name": "UniProt",
"db_id": "Q6ZYM3"
},
{
"db_name": "UniProt",
"db_id": "Q865F0"
},
{
"db_name": "UniProt",
"db_id": "Q95MP2"
},
{
"db_name": "UniProt",
"db_id": "Q99JA2"
},
{
"db_name": "UniProt",
"db_id": "Q9H1Y0"
},
{
"db_name": "UniProt",
"db_id": "Q9NQ94"
}
]
},
{
"id": "DS.d775.s0.e1",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
105,
112
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
}
] | [] | [] | [
{
"id": "DS.d775.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d775.s0.e1",
"arg2_id": "DS.d775.s0.e0",
"normalized": []
}
] |
DS.d776 | 18703100 | [
{
"id": "DS.d776.s0",
"type": "",
"text": [
"Using a set of experiments aimed at manipulate a putative l-glutamate/NMDA/NO signal transduction pathway, we have demonstrated, by quantitative real-time PCR, that NMDA enhances the expression of GnRH mRNA in a dose-response manner."
],
"offsets": [
[
0,
233
]
]
}
] | [
{
"id": "DS.d776.s0.e0",
"type": "compound",
"text": [
"l-glutamate"
],
"offsets": [
[
58,
69
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "33032"
}
]
},
{
"id": "DS.d776.s0.e1",
"type": "compound",
"text": [
"NMDA"
],
"offsets": [
[
70,
74
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "22880"
}
]
},
{
"id": "DS.d776.s0.e2",
"type": "compound",
"text": [
"NMDA"
],
"offsets": [
[
165,
169
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "22880"
}
]
},
{
"id": "DS.d776.s0.e3",
"type": "protein",
"text": [
"GnRH"
],
"offsets": [
[
197,
201
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P27429"
}
]
}
] | [] | [] | [
{
"id": "DS.d776.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d776.s0.e0",
"arg2_id": "DS.d776.s0.e3",
"normalized": []
},
{
"id": "DS.d776.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d776.s0.e1",
"arg2_id": "DS.d776.s0.e3",
"normalized": []
}
] |
DS.d777 | 18703333 | [
{
"id": "DS.d777.s0",
"type": "",
"text": [
"Reaction parameters for the production of XOS from corncob using endoxylanase from Aspergillus oryzae MTCC 5154 were optimized and an XOS yield of 10.2+/-0.14 mg ml(-1) corresponding to 81+/-3.9% with 73.5% xylobiose was obtained."
],
"offsets": [
[
0,
230
]
]
}
] | [
{
"id": "DS.d777.s0.e0",
"type": "protein",
"text": [
"endoxylanase"
],
"offsets": [
[
65,
77
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q60042"
}
]
},
{
"id": "DS.d777.s0.e1",
"type": "compound",
"text": [
"xylobiose"
],
"offsets": [
[
207,
216
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "439538"
}
]
}
] | [] | [] | [] |
DS.d778 | 18703532 | [
{
"id": "DS.d778.s0",
"type": "",
"text": [
"Cilostazol inhibits cytokine-induced nuclear factor-kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells."
],
"offsets": [
[
0,
144
]
]
},
{
"id": "DS.d778.s1",
"type": "",
"text": [
"Cilostazol is a selective inhibitor of phosphodiesterase 3 that increases intracellular cyclic AMP (cAMP) levels and activates protein kinase A, thereby inhibiting platelet aggregation and inducing peripheral vasodilation."
],
"offsets": [
[
145,
367
]
]
},
{
"id": "DS.d778.s2",
"type": "",
"text": [
"We hypothesized that cilostazol may prevent inflammatory cytokine induced-nuclear factor (NF)-kappaB activation by activating AMP-activated protein kinase (AMPK) in vascular endothelial cells."
],
"offsets": [
[
368,
560
]
]
}
] | [
{
"id": "DS.d778.s0.e0",
"type": "compound",
"text": [
"Cilostazol"
],
"offsets": [
[
0,
10
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2754"
}
]
},
{
"id": "DS.d778.s0.e1",
"type": "protein",
"text": [
"protein kinase"
],
"offsets": [
[
88,
102
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P00513"
},
{
"db_name": "UniProt",
"db_id": "P25848"
}
]
},
{
"id": "DS.d778.s1.e0",
"type": "compound",
"text": [
"Cilostazol"
],
"offsets": [
[
145,
155
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2754"
}
]
},
{
"id": "DS.d778.s1.e1",
"type": "compound",
"text": [
"cAMP"
],
"offsets": [
[
245,
249
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6076"
}
]
},
{
"id": "DS.d778.s1.e2",
"type": "protein",
"text": [
"protein kinase A"
],
"offsets": [
[
272,
288
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q05608"
},
{
"db_name": "UniProt",
"db_id": "Q9RI12"
}
]
},
{
"id": "DS.d778.s2.e0",
"type": "compound",
"text": [
"cilostazol"
],
"offsets": [
[
389,
399
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2754"
}
]
},
{
"id": "DS.d778.s2.e1",
"type": "protein",
"text": [
"protein kinase"
],
"offsets": [
[
508,
522
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P00513"
},
{
"db_name": "UniProt",
"db_id": "P25848"
}
]
},
{
"id": "DS.d778.s2.e2",
"type": "protein",
"text": [
"AMPK"
],
"offsets": [
[
524,
528
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P54646"
},
{
"db_name": "UniProt",
"db_id": "Q09136"
},
{
"db_name": "UniProt",
"db_id": "Q9Y478"
}
]
}
] | [] | [] | [
{
"id": "DS.d778.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d778.s0.e0",
"arg2_id": "DS.d778.s0.e1",
"normalized": []
},
{
"id": "DS.d778.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d778.s1.e0",
"arg2_id": "DS.d778.s1.e2",
"normalized": []
},
{
"id": "DS.d778.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d778.s2.e0",
"arg2_id": "DS.d778.s2.e2",
"normalized": []
},
{
"id": "DS.d778.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d778.s2.e0",
"arg2_id": "DS.d778.s2.e1",
"normalized": []
}
] |
DS.d779 | 18703622 | [
{
"id": "DS.d779.s0",
"type": "",
"text": [
"Serum estradiol (E2) levels were not altered at any time point after IGF-I, demonstrating that the increased KiSS-1 expression observed was not caused by an elevation in E2."
],
"offsets": [
[
0,
173
]
]
}
] | [
{
"id": "DS.d779.s0.e0",
"type": "compound",
"text": [
"estradiol"
],
"offsets": [
[
6,
15
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5757"
}
]
},
{
"id": "DS.d779.s0.e1",
"type": "protein",
"text": [
"IGF-I"
],
"offsets": [
[
69,
74
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05017"
},
{
"db_name": "UniProt",
"db_id": "P07455"
},
{
"db_name": "UniProt",
"db_id": "P08025"
},
{
"db_name": "UniProt",
"db_id": "P10763"
},
{
"db_name": "UniProt",
"db_id": "P16545"
},
{
"db_name": "UniProt",
"db_id": "P17085"
},
{
"db_name": "UniProt",
"db_id": "P17647"
},
{
"db_name": "UniProt",
"db_id": "P18254"
},
{
"db_name": "UniProt",
"db_id": "P33712"
},
{
"db_name": "UniProt",
"db_id": "P51457"
},
{
"db_name": "UniProt",
"db_id": "P51458"
},
{
"db_name": "UniProt",
"db_id": "P51462"
},
{
"db_name": "UniProt",
"db_id": "Q02815"
},
{
"db_name": "UniProt",
"db_id": "Q28933"
},
{
"db_name": "UniProt",
"db_id": "Q68LC0"
},
{
"db_name": "UniProt",
"db_id": "Q6GUL6"
},
{
"db_name": "UniProt",
"db_id": "Q6IVA5"
},
{
"db_name": "UniProt",
"db_id": "Q6JLX1"
},
{
"db_name": "UniProt",
"db_id": "Q95222"
}
]
}
] | [] | [] | [] |
DS.d780 | 18703794 | [
{
"id": "DS.d780.s0",
"type": "",
"text": [
"A2aR stimulation inhibits HA fragment-induced pro-fibrotic genes TNF-alpha, keratinocyte chemoattractant (KC), macrophage inflammatory protein (MIP)-2, and MIP-1alpha while simultaneously synergizing with hyaluronan fragments to up-regulate the TH1 cytokine IL-12."
],
"offsets": [
[
0,
264
]
]
}
] | [
{
"id": "DS.d780.s0.e0",
"type": "protein",
"text": [
"TNF-alpha"
],
"offsets": [
[
65,
74
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35734"
},
{
"db_name": "UniProt",
"db_id": "O77510"
},
{
"db_name": "UniProt",
"db_id": "O77764"
},
{
"db_name": "UniProt",
"db_id": "P01375"
},
{
"db_name": "UniProt",
"db_id": "P04924"
},
{
"db_name": "UniProt",
"db_id": "P06804"
},
{
"db_name": "UniProt",
"db_id": "P13296"
},
{
"db_name": "UniProt",
"db_id": "P16599"
},
{
"db_name": "UniProt",
"db_id": "P19101"
},
{
"db_name": "UniProt",
"db_id": "P23383"
},
{
"db_name": "UniProt",
"db_id": "P23563"
},
{
"db_name": "UniProt",
"db_id": "P29553"
},
{
"db_name": "UniProt",
"db_id": "P33620"
},
{
"db_name": "UniProt",
"db_id": "P36939"
},
{
"db_name": "UniProt",
"db_id": "P48094"
},
{
"db_name": "UniProt",
"db_id": "P51435"
},
{
"db_name": "UniProt",
"db_id": "P51742"
},
{
"db_name": "UniProt",
"db_id": "P51743"
},
{
"db_name": "UniProt",
"db_id": "P59684"
},
{
"db_name": "UniProt",
"db_id": "P59693"
},
{
"db_name": "UniProt",
"db_id": "P59694"
},
{
"db_name": "UniProt",
"db_id": "P59695"
},
{
"db_name": "UniProt",
"db_id": "P79337"
},
{
"db_name": "UniProt",
"db_id": "P79374"
},
{
"db_name": "UniProt",
"db_id": "Q06599"
},
{
"db_name": "UniProt",
"db_id": "Q19LH4"
},
{
"db_name": "UniProt",
"db_id": "Q1G1A2"
},
{
"db_name": "UniProt",
"db_id": "Q1WM27"
},
{
"db_name": "UniProt",
"db_id": "Q2MH05"
},
{
"db_name": "UniProt",
"db_id": "Q539C2"
},
{
"db_name": "UniProt",
"db_id": "Q75N23"
},
{
"db_name": "UniProt",
"db_id": "Q8HZD9"
},
{
"db_name": "UniProt",
"db_id": "Q8JFG3"
},
{
"db_name": "UniProt",
"db_id": "Q8MKG8"
},
{
"db_name": "UniProt",
"db_id": "Q8WNR1"
},
{
"db_name": "UniProt",
"db_id": "Q9BEA1"
}
]
},
{
"id": "DS.d780.s0.e1",
"type": "protein",
"text": [
"MIP"
],
"offsets": [
[
144,
147
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P06624"
},
{
"db_name": "UniProt",
"db_id": "P28238"
},
{
"db_name": "UniProt",
"db_id": "P30301"
},
{
"db_name": "UniProt",
"db_id": "P35999"
},
{
"db_name": "UniProt",
"db_id": "P37932"
},
{
"db_name": "UniProt",
"db_id": "Q01992"
},
{
"db_name": "UniProt",
"db_id": "Q09734"
},
{
"db_name": "UniProt",
"db_id": "Q10415"
},
{
"db_name": "UniProt",
"db_id": "Q6J8I9"
},
{
"db_name": "UniProt",
"db_id": "Q6RZ07"
},
{
"db_name": "UniProt",
"db_id": "Q92973"
},
{
"db_name": "UniProt",
"db_id": "Q99797"
}
]
},
{
"id": "DS.d780.s0.e2",
"type": "protein",
"text": [
"MIP-1alpha"
],
"offsets": [
[
156,
166
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10147"
},
{
"db_name": "UniProt",
"db_id": "P10855"
},
{
"db_name": "UniProt",
"db_id": "P50229"
},
{
"db_name": "UniProt",
"db_id": "Q5I1Z0"
},
{
"db_name": "UniProt",
"db_id": "Q8HYQ3"
},
{
"db_name": "UniProt",
"db_id": "Q8SQA6"
}
]
},
{
"id": "DS.d780.s0.e3",
"type": "compound",
"text": [
"hyaluronan"
],
"offsets": [
[
205,
215
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "24759"
}
]
}
] | [] | [] | [] |
DS.d781 | 18703795 | [
{
"id": "DS.d781.s0",
"type": "",
"text": [
"In addition, treatment of primary mouse lung fibroblasts with ADMA stimulated arginase activity and collagen formation in vitro."
],
"offsets": [
[
0,
128
]
]
},
{
"id": "DS.d781.s1",
"type": "",
"text": [
"These data support the idea that ADMA may play a role in airway diseases, including asthma and pulmonary fibrosis, through NOS inhibition and enhancement of arginase activity."
],
"offsets": [
[
129,
304
]
]
}
] | [
{
"id": "DS.d781.s0.e0",
"type": "compound",
"text": [
"ADMA"
],
"offsets": [
[
62,
66
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "123831"
}
]
},
{
"id": "DS.d781.s0.e1",
"type": "protein",
"text": [
"arginase"
],
"offsets": [
[
78,
86
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O49046"
},
{
"db_name": "UniProt",
"db_id": "P00812"
},
{
"db_name": "UniProt",
"db_id": "P0A2X9"
},
{
"db_name": "UniProt",
"db_id": "P0A2Y0"
},
{
"db_name": "UniProt",
"db_id": "P0A2Y1"
},
{
"db_name": "UniProt",
"db_id": "P14012"
},
{
"db_name": "UniProt",
"db_id": "P33280"
},
{
"db_name": "UniProt",
"db_id": "P37818"
},
{
"db_name": "UniProt",
"db_id": "P39138"
},
{
"db_name": "UniProt",
"db_id": "P40906"
},
{
"db_name": "UniProt",
"db_id": "P46637"
},
{
"db_name": "UniProt",
"db_id": "P53608"
},
{
"db_name": "UniProt",
"db_id": "P60086"
},
{
"db_name": "UniProt",
"db_id": "P60087"
},
{
"db_name": "UniProt",
"db_id": "P60088"
},
{
"db_name": "UniProt",
"db_id": "Q10066"
},
{
"db_name": "UniProt",
"db_id": "Q12611"
},
{
"db_name": "UniProt",
"db_id": "Q1E180"
},
{
"db_name": "UniProt",
"db_id": "Q6G7E9"
},
{
"db_name": "UniProt",
"db_id": "Q6GER3"
},
{
"db_name": "UniProt",
"db_id": "Q74ZW4"
},
{
"db_name": "UniProt",
"db_id": "Q7M0Z3"
},
{
"db_name": "UniProt",
"db_id": "Q8NVE3"
}
]
},
{
"id": "DS.d781.s1.e0",
"type": "compound",
"text": [
"ADMA"
],
"offsets": [
[
162,
166
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "123831"
}
]
},
{
"id": "DS.d781.s1.e1",
"type": "protein",
"text": [
"NOS"
],
"offsets": [
[
252,
255
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O54705"
},
{
"db_name": "UniProt",
"db_id": "O61309"
},
{
"db_name": "UniProt",
"db_id": "O61608"
},
{
"db_name": "UniProt",
"db_id": "Q26240"
},
{
"db_name": "UniProt",
"db_id": "Q28969"
},
{
"db_name": "UniProt",
"db_id": "Q9I9M2"
}
]
},
{
"id": "DS.d781.s1.e2",
"type": "protein",
"text": [
"arginase"
],
"offsets": [
[
286,
294
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O49046"
},
{
"db_name": "UniProt",
"db_id": "P00812"
},
{
"db_name": "UniProt",
"db_id": "P0A2X9"
},
{
"db_name": "UniProt",
"db_id": "P0A2Y0"
},
{
"db_name": "UniProt",
"db_id": "P0A2Y1"
},
{
"db_name": "UniProt",
"db_id": "P14012"
},
{
"db_name": "UniProt",
"db_id": "P33280"
},
{
"db_name": "UniProt",
"db_id": "P37818"
},
{
"db_name": "UniProt",
"db_id": "P39138"
},
{
"db_name": "UniProt",
"db_id": "P40906"
},
{
"db_name": "UniProt",
"db_id": "P46637"
},
{
"db_name": "UniProt",
"db_id": "P53608"
},
{
"db_name": "UniProt",
"db_id": "P60086"
},
{
"db_name": "UniProt",
"db_id": "P60087"
},
{
"db_name": "UniProt",
"db_id": "P60088"
},
{
"db_name": "UniProt",
"db_id": "Q10066"
},
{
"db_name": "UniProt",
"db_id": "Q12611"
},
{
"db_name": "UniProt",
"db_id": "Q1E180"
},
{
"db_name": "UniProt",
"db_id": "Q6G7E9"
},
{
"db_name": "UniProt",
"db_id": "Q6GER3"
},
{
"db_name": "UniProt",
"db_id": "Q74ZW4"
},
{
"db_name": "UniProt",
"db_id": "Q7M0Z3"
},
{
"db_name": "UniProt",
"db_id": "Q8NVE3"
}
]
}
] | [] | [] | [
{
"id": "DS.d781.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d781.s0.e0",
"arg2_id": "DS.d781.s0.e1",
"normalized": []
},
{
"id": "DS.d781.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d781.s1.e0",
"arg2_id": "DS.d781.s1.e2",
"normalized": []
},
{
"id": "DS.d781.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d781.s1.e0",
"arg2_id": "DS.d781.s1.e1",
"normalized": []
}
] |
DS.d782 | 18703867 | [
{
"id": "DS.d782.s0",
"type": "",
"text": [
"Osteopontin (OPN) inhibits the growth of calcium oxalate monohydrate (COM) and other crystal phases in a phosphorylation-dependent manner."
],
"offsets": [
[
0,
138
]
]
}
] | [
{
"id": "DS.d782.s0.e0",
"type": "protein",
"text": [
"OPN"
],
"offsets": [
[
13,
16
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10451"
},
{
"db_name": "UniProt",
"db_id": "P14287"
},
{
"db_name": "UniProt",
"db_id": "P31096"
},
{
"db_name": "UniProt",
"db_id": "Q9XSY9"
}
]
},
{
"id": "DS.d782.s0.e1",
"type": "compound",
"text": [
"calcium oxalate monohydrate"
],
"offsets": [
[
41,
68
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "971"
}
]
}
] | [] | [] | [
{
"id": "DS.d782.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d782.s0.e1",
"arg2_id": "DS.d782.s0.e0",
"normalized": []
}
] |
DS.d783 | 18703992 | [
{
"id": "DS.d783.s0",
"type": "",
"text": [
"Prostaglandins D2, E2, and F2alpha were increased in the tissues from mouse pups exposed to >95% O2 at 7 d indicating a differential expression of cyclooxygenase-2 products."
],
"offsets": [
[
0,
176
]
]
}
] | [
{
"id": "DS.d783.s0.e0",
"type": "compound",
"text": [
"O2"
],
"offsets": [
[
100,
102
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "977"
},
{
"db_name": "PubChem",
"db_id": "5359597"
}
]
},
{
"id": "DS.d783.s0.e1",
"type": "protein",
"text": [
"cyclooxygenase-2"
],
"offsets": [
[
150,
166
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O02768"
},
{
"db_name": "UniProt",
"db_id": "O19183"
},
{
"db_name": "UniProt",
"db_id": "O62698"
},
{
"db_name": "UniProt",
"db_id": "O62725"
},
{
"db_name": "UniProt",
"db_id": "P27607"
},
{
"db_name": "UniProt",
"db_id": "P35354"
},
{
"db_name": "UniProt",
"db_id": "P35355"
},
{
"db_name": "UniProt",
"db_id": "P70682"
},
{
"db_name": "UniProt",
"db_id": "P79208"
},
{
"db_name": "UniProt",
"db_id": "Q05769"
}
]
}
] | [] | [] | [
{
"id": "DS.d783.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d783.s0.e0",
"arg2_id": "DS.d783.s0.e1",
"normalized": []
}
] |
DS.d784 | 18704001 | [
{
"id": "DS.d784.s0",
"type": "",
"text": [
"Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction."
],
"offsets": [
[
0,
144
]
]
},
{
"id": "DS.d784.s1",
"type": "",
"text": [
"Glucose stimulated insulin secretion (GSIS) was lower in the Glu group."
],
"offsets": [
[
145,
216
]
]
}
] | [
{
"id": "DS.d784.s0.e0",
"type": "compound",
"text": [
"Glucose"
],
"offsets": [
[
0,
7
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d784.s0.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
74,
81
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d784.s1.e0",
"type": "compound",
"text": [
"Glucose"
],
"offsets": [
[
145,
152
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d784.s1.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
164,
171
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
}
] | [] | [] | [
{
"id": "DS.d784.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d784.s0.e0",
"arg2_id": "DS.d784.s0.e1",
"normalized": []
},
{
"id": "DS.d784.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d784.s1.e0",
"arg2_id": "DS.d784.s1.e1",
"normalized": []
}
] |
DS.d785 | 18704095 | [
{
"id": "DS.d785.s0",
"type": "",
"text": [
"These data confirm that endogenous miR-34a regulates GRM7 levels and supports the notion that miR-34a contributes to the effects of lithium and VPA on GRM7."
],
"offsets": [
[
0,
156
]
]
}
] | [
{
"id": "DS.d785.s0.e1",
"type": "protein",
"text": [
"GRM7"
],
"offsets": [
[
53,
57
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q14831"
},
{
"db_name": "UniProt",
"db_id": "Q5RDQ8"
}
]
},
{
"id": "DS.d785.s0.e3",
"type": "compound",
"text": [
"lithium"
],
"offsets": [
[
132,
139
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "28486"
},
{
"db_name": "PubChem",
"db_id": "3028194"
}
]
},
{
"id": "DS.d785.s0.e4",
"type": "protein",
"text": [
"GRM7"
],
"offsets": [
[
151,
155
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q14831"
},
{
"db_name": "UniProt",
"db_id": "Q5RDQ8"
}
]
}
] | [] | [] | [
{
"id": "DS.d785.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d785.s0.e3",
"arg2_id": "DS.d785.s0.e1",
"normalized": []
}
] |
DS.d786 | 18704096 | [
{
"id": "DS.d786.s0",
"type": "",
"text": [
"These results confirm the therapeutic potential of mGluR5 blockade on motor symptoms induced by reduced striatal dopamine function."
],
"offsets": [
[
0,
131
]
]
},
{
"id": "DS.d786.s1",
"type": "",
"text": [
"Further, they demonstrate that mGluR5 blockade may also have beneficial effects on cognitive deficits induced by dopamine depletion."
],
"offsets": [
[
132,
264
]
]
}
] | [
{
"id": "DS.d786.s0.e0",
"type": "protein",
"text": [
"mGluR5"
],
"offsets": [
[
51,
57
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P31424"
},
{
"db_name": "UniProt",
"db_id": "P41594"
}
]
},
{
"id": "DS.d786.s0.e1",
"type": "compound",
"text": [
"dopamine"
],
"offsets": [
[
113,
121
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "681"
}
]
},
{
"id": "DS.d786.s1.e0",
"type": "protein",
"text": [
"mGluR5"
],
"offsets": [
[
163,
169
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P31424"
},
{
"db_name": "UniProt",
"db_id": "P41594"
}
]
},
{
"id": "DS.d786.s1.e1",
"type": "compound",
"text": [
"dopamine"
],
"offsets": [
[
245,
253
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "681"
}
]
}
] | [] | [] | [
{
"id": "DS.d786.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d786.s0.e1",
"arg2_id": "DS.d786.s0.e0",
"normalized": []
},
{
"id": "DS.d786.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d786.s1.e1",
"arg2_id": "DS.d786.s1.e0",
"normalized": []
}
] |
DS.d787 | 18704103 | [
{
"id": "DS.d787.s0",
"type": "",
"text": [
"Here, we found that the addition of glucocorticoids, such as dexamethasone and cortisol, to cultured human keratinocytes increased their TLR2 gene expression."
],
"offsets": [
[
0,
158
]
]
},
{
"id": "DS.d787.s1",
"type": "",
"text": [
"Gene expression of mitogen-activated protein kinase (MAPK) phosphatase-1 was also increased by the addition of dexamethasone."
],
"offsets": [
[
159,
284
]
]
}
] | [
{
"id": "DS.d787.s0.e0",
"type": "compound",
"text": [
"dexamethasone"
],
"offsets": [
[
61,
74
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5743"
}
]
},
{
"id": "DS.d787.s0.e1",
"type": "compound",
"text": [
"cortisol"
],
"offsets": [
[
79,
87
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5754"
}
]
},
{
"id": "DS.d787.s0.e2",
"type": "protein",
"text": [
"TLR2"
],
"offsets": [
[
137,
141
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O60603"
},
{
"db_name": "UniProt",
"db_id": "Q2V897"
},
{
"db_name": "UniProt",
"db_id": "Q689D1"
},
{
"db_name": "UniProt",
"db_id": "Q95LA9"
},
{
"db_name": "UniProt",
"db_id": "Q95M53"
},
{
"db_name": "UniProt",
"db_id": "Q9R1F8"
}
]
},
{
"id": "DS.d787.s1.e0",
"type": "protein",
"text": [
"MAPK"
],
"offsets": [
[
212,
216
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O42781"
},
{
"db_name": "UniProt",
"db_id": "P27638"
},
{
"db_name": "UniProt",
"db_id": "Q00859"
}
]
},
{
"id": "DS.d787.s1.e1",
"type": "compound",
"text": [
"dexamethasone"
],
"offsets": [
[
270,
283
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5743"
}
]
}
] | [] | [] | [
{
"id": "DS.d787.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d787.s0.e1",
"arg2_id": "DS.d787.s0.e2",
"normalized": []
},
{
"id": "DS.d787.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d787.s0.e0",
"arg2_id": "DS.d787.s0.e2",
"normalized": []
},
{
"id": "DS.d787.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d787.s1.e1",
"arg2_id": "DS.d787.s1.e0",
"normalized": []
}
] |
DS.d788 | 18704264 | [
{
"id": "DS.d788.s0",
"type": "",
"text": [
"Administration of B(a)P (50 mg/kg body weight) to mice resulted in increased lipid peroxides (LPO), lung specific tumor marker carcinoembryonic antigen (CEA) and serum marker enzymes aryl hydrocarbon hydroxylase (AHH), gamma glutamyl transpeptidase (GGT), 5'nucleotidase (5'ND) and lactate dehydrogenase (LDH) with concomitant decrease in the levels of tissue antioxidants like superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH), vitamin E and vitamin C."
],
"offsets": [
[
0,
503
]
]
}
] | [
{
"id": "DS.d788.s0.e0",
"type": "protein",
"text": [
"carcinoembryonic antigen"
],
"offsets": [
[
127,
151
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P06731"
}
]
},
{
"id": "DS.d788.s0.e1",
"type": "protein",
"text": [
"CEA"
],
"offsets": [
[
153,
156
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P06731"
}
]
},
{
"id": "DS.d788.s0.e2",
"type": "protein",
"text": [
"GGT"
],
"offsets": [
[
250,
253
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P15557"
},
{
"db_name": "UniProt",
"db_id": "P19440"
},
{
"db_name": "UniProt",
"db_id": "P20735"
},
{
"db_name": "UniProt",
"db_id": "Q05053"
}
]
},
{
"id": "DS.d788.s0.e3",
"type": "protein",
"text": [
"5'nucleotidase"
],
"offsets": [
[
256,
270
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P07024"
},
{
"db_name": "UniProt",
"db_id": "P52307"
},
{
"db_name": "UniProt",
"db_id": "Q56878"
},
{
"db_name": "UniProt",
"db_id": "Q9I767"
},
{
"db_name": "UniProt",
"db_id": "Q9RN37"
},
{
"db_name": "UniProt",
"db_id": "Q9XZ43"
}
]
},
{
"id": "DS.d788.s0.e4",
"type": "protein",
"text": [
"LDH"
],
"offsets": [
[
305,
308
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P29038"
},
{
"db_name": "UniProt",
"db_id": "P33571"
},
{
"db_name": "UniProt",
"db_id": "P93052"
},
{
"db_name": "UniProt",
"db_id": "Q27797"
},
{
"db_name": "UniProt",
"db_id": "Q27888"
},
{
"db_name": "UniProt",
"db_id": "Q95028"
},
{
"db_name": "UniProt",
"db_id": "Q99289"
}
]
},
{
"id": "DS.d788.s0.e5",
"type": "protein",
"text": [
"superoxide dismutase"
],
"offsets": [
[
378,
398
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O50258"
}
]
},
{
"id": "DS.d788.s0.e6",
"type": "protein",
"text": [
"SOD"
],
"offsets": [
[
400,
403
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12933"
},
{
"db_name": "UniProt",
"db_id": "O22668"
},
{
"db_name": "UniProt",
"db_id": "O75007"
},
{
"db_name": "UniProt",
"db_id": "P24705"
},
{
"db_name": "UniProt",
"db_id": "P51547"
},
{
"db_name": "UniProt",
"db_id": "P93258"
},
{
"db_name": "UniProt",
"db_id": "Q01137"
},
{
"db_name": "UniProt",
"db_id": "Q27666"
},
{
"db_name": "UniProt",
"db_id": "Q9SM64"
}
]
},
{
"id": "DS.d788.s0.e7",
"type": "protein",
"text": [
"catalase"
],
"offsets": [
[
406,
414
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O24339"
},
{
"db_name": "UniProt",
"db_id": "O52762"
},
{
"db_name": "UniProt",
"db_id": "O62839"
},
{
"db_name": "UniProt",
"db_id": "O68146"
},
{
"db_name": "UniProt",
"db_id": "O77229"
},
{
"db_name": "UniProt",
"db_id": "O93662"
},
{
"db_name": "UniProt",
"db_id": "O97492"
},
{
"db_name": "UniProt",
"db_id": "P00432"
},
{
"db_name": "UniProt",
"db_id": "P04040"
},
{
"db_name": "UniProt",
"db_id": "P04762"
},
{
"db_name": "UniProt",
"db_id": "P07145"
},
{
"db_name": "UniProt",
"db_id": "P0A323"
},
{
"db_name": "UniProt",
"db_id": "P0A324"
},
{
"db_name": "UniProt",
"db_id": "P0A325"
},
{
"db_name": "UniProt",
"db_id": "P0A326"
},
{
"db_name": "UniProt",
"db_id": "P0A327"
},
{
"db_name": "UniProt",
"db_id": "P11934"
},
{
"db_name": "UniProt",
"db_id": "P17336"
},
{
"db_name": "UniProt",
"db_id": "P24168"
},
{
"db_name": "UniProt",
"db_id": "P24270"
},
{
"db_name": "UniProt",
"db_id": "P25890"
},
{
"db_name": "UniProt",
"db_id": "P29422"
},
{
"db_name": "UniProt",
"db_id": "P30265"
},
{
"db_name": "UniProt",
"db_id": "P30266"
},
{
"db_name": "UniProt",
"db_id": "P32290"
},
{
"db_name": "UniProt",
"db_id": "P42321"
},
{
"db_name": "UniProt",
"db_id": "P44390"
},
{
"db_name": "UniProt",
"db_id": "P45737"
},
{
"db_name": "UniProt",
"db_id": "P45739"
},
{
"db_name": "UniProt",
"db_id": "P55304"
},
{
"db_name": "UniProt",
"db_id": "P55306"
},
{
"db_name": "UniProt",
"db_id": "P55310"
},
{
"db_name": "UniProt",
"db_id": "P55311"
},
{
"db_name": "UniProt",
"db_id": "P55313"
},
{
"db_name": "UniProt",
"db_id": "P77872"
},
{
"db_name": "UniProt",
"db_id": "P81138"
},
{
"db_name": "UniProt",
"db_id": "P90682"
},
{
"db_name": "UniProt",
"db_id": "Q27710"
},
{
"db_name": "UniProt",
"db_id": "Q49XC1"
},
{
"db_name": "UniProt",
"db_id": "Q4L643"
},
{
"db_name": "UniProt",
"db_id": "Q59296"
},
{
"db_name": "UniProt",
"db_id": "Q59337"
},
{
"db_name": "UniProt",
"db_id": "Q59602"
},
{
"db_name": "UniProt",
"db_id": "Q59714"
},
{
"db_name": "UniProt",
"db_id": "Q5HG86"
},
{
"db_name": "UniProt",
"db_id": "Q5HPK8"
},
{
"db_name": "UniProt",
"db_id": "Q5RF10"
},
{
"db_name": "UniProt",
"db_id": "Q64405"
},
{
"db_name": "UniProt",
"db_id": "Q6G9M4"
},
{
"db_name": "UniProt",
"db_id": "Q6GH72"
},
{
"db_name": "UniProt",
"db_id": "Q7A5T2"
},
{
"db_name": "UniProt",
"db_id": "Q8CPD0"
},
{
"db_name": "UniProt",
"db_id": "Q8FWU0"
},
{
"db_name": "UniProt",
"db_id": "Q8NWV5"
},
{
"db_name": "UniProt",
"db_id": "Q8X1P0"
},
{
"db_name": "UniProt",
"db_id": "Q8Y3P9"
},
{
"db_name": "UniProt",
"db_id": "Q926X0"
},
{
"db_name": "UniProt",
"db_id": "Q99UE2"
},
{
"db_name": "UniProt",
"db_id": "Q9AXH0"
},
{
"db_name": "UniProt",
"db_id": "Q9KW19"
},
{
"db_name": "UniProt",
"db_id": "Q9L4S1"
},
{
"db_name": "UniProt",
"db_id": "Q9M5L6"
},
{
"db_name": "UniProt",
"db_id": "Q9PT92"
},
{
"db_name": "UniProt",
"db_id": "Q9PWF7"
},
{
"db_name": "UniProt",
"db_id": "Q9Z598"
},
{
"db_name": "UniProt",
"db_id": "Q9ZKX5"
},
{
"db_name": "UniProt",
"db_id": "Q9ZN99"
}
]
},
{
"id": "DS.d788.s0.e8",
"type": "protein",
"text": [
"CAT"
],
"offsets": [
[
416,
419
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62839"
},
{
"db_name": "UniProt",
"db_id": "O97492"
},
{
"db_name": "UniProt",
"db_id": "P00432"
},
{
"db_name": "UniProt",
"db_id": "P00485"
},
{
"db_name": "UniProt",
"db_id": "P00486"
},
{
"db_name": "UniProt",
"db_id": "P00487"
},
{
"db_name": "UniProt",
"db_id": "P04040"
},
{
"db_name": "UniProt",
"db_id": "P06135"
},
{
"db_name": "UniProt",
"db_id": "P07641"
},
{
"db_name": "UniProt",
"db_id": "P11504"
},
{
"db_name": "UniProt",
"db_id": "P20074"
},
{
"db_name": "UniProt",
"db_id": "P22782"
},
{
"db_name": "UniProt",
"db_id": "P25309"
},
{
"db_name": "UniProt",
"db_id": "P25819"
},
{
"db_name": "UniProt",
"db_id": "P26825"
},
{
"db_name": "UniProt",
"db_id": "P26826"
},
{
"db_name": "UniProt",
"db_id": "P32796"
},
{
"db_name": "UniProt",
"db_id": "P36882"
},
{
"db_name": "UniProt",
"db_id": "P36883"
},
{
"db_name": "UniProt",
"db_id": "P43155"
},
{
"db_name": "UniProt",
"db_id": "P47934"
},
{
"db_name": "UniProt",
"db_id": "P49417"
},
{
"db_name": "UniProt",
"db_id": "P52826"
},
{
"db_name": "UniProt",
"db_id": "P58777"
},
{
"db_name": "UniProt",
"db_id": "P62577"
},
{
"db_name": "UniProt",
"db_id": "P62578"
},
{
"db_name": "UniProt",
"db_id": "P62579"
},
{
"db_name": "UniProt",
"db_id": "P62580"
},
{
"db_name": "UniProt",
"db_id": "P90682"
},
{
"db_name": "UniProt",
"db_id": "Q00614"
},
{
"db_name": "UniProt",
"db_id": "Q02736"
},
{
"db_name": "UniProt",
"db_id": "Q03058"
},
{
"db_name": "UniProt",
"db_id": "Q5RF10"
},
{
"db_name": "UniProt",
"db_id": "Q64405"
},
{
"db_name": "UniProt",
"db_id": "Q704S8"
},
{
"db_name": "UniProt",
"db_id": "Q9M5L6"
},
{
"db_name": "UniProt",
"db_id": "Q9PWF7"
}
]
},
{
"id": "DS.d788.s0.e9",
"type": "protein",
"text": [
"glutathione peroxidase"
],
"offsets": [
[
422,
444
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O32770"
},
{
"db_name": "UniProt",
"db_id": "O59858"
},
{
"db_name": "UniProt",
"db_id": "Q00277"
},
{
"db_name": "UniProt",
"db_id": "Q9CFV1"
}
]
},
{
"id": "DS.d788.s0.e10",
"type": "compound",
"text": [
"reduced glutathione"
],
"offsets": [
[
452,
471
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
},
{
"id": "DS.d788.s0.e11",
"type": "compound",
"text": [
"GSH"
],
"offsets": [
[
473,
476
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
},
{
"id": "DS.d788.s0.e12",
"type": "compound",
"text": [
"vitamin E"
],
"offsets": [
[
479,
488
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2116"
},
{
"db_name": "PubChem",
"db_id": "14985"
},
{
"db_name": "PubChem",
"db_id": "1548900"
},
{
"db_name": "PubChem",
"db_id": "1742129"
}
]
},
{
"id": "DS.d788.s0.e13",
"type": "compound",
"text": [
"vitamin C"
],
"offsets": [
[
493,
502
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "54670067"
}
]
}
] | [] | [] | [] |
DS.d789 | 18704417 | [
{
"id": "DS.d789.s0",
"type": "",
"text": [
"Achieving CCgR within 12 months and maintaining it without an increase in BCR-ABL transcripts might indicate that low-dose imatinib therapy can produce acceptable outcomes without excess toxicity."
],
"offsets": [
[
0,
196
]
]
}
] | [
{
"id": "DS.d789.s0.e0",
"type": "protein",
"text": [
"BCR"
],
"offsets": [
[
74,
77
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P11274"
}
]
},
{
"id": "DS.d789.s0.e1",
"type": "protein",
"text": [
"ABL"
],
"offsets": [
[
78,
81
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P00519"
},
{
"db_name": "UniProt",
"db_id": "P00521"
},
{
"db_name": "UniProt",
"db_id": "P10447"
},
{
"db_name": "UniProt",
"db_id": "P11681"
},
{
"db_name": "UniProt",
"db_id": "Q00022"
}
]
},
{
"id": "DS.d789.s0.e2",
"type": "compound",
"text": [
"imatinib"
],
"offsets": [
[
123,
131
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5291"
}
]
}
] | [] | [] | [
{
"id": "DS.d789.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d789.s0.e2",
"arg2_id": "DS.d789.s0.e0",
"normalized": []
},
{
"id": "DS.d789.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d789.s0.e2",
"arg2_id": "DS.d789.s0.e1",
"normalized": []
}
] |
DS.d790 | 18704487 | [
{
"id": "DS.d790.s0",
"type": "",
"text": [
"Rac1 (-/-) platelets displayed defective thrombus formation on collagen under flow conditions which could be fully restored by co-infusion of ADP and the TxA(2) analog U46619, indicating that impaired GPVI-, but not G-protein signaling, was responsible for the observed defect."
],
"offsets": [
[
0,
277
]
]
}
] | [
{
"id": "DS.d790.s0.e0",
"type": "protein",
"text": [
"Rac1"
],
"offsets": [
[
0,
4
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P40792"
},
{
"db_name": "UniProt",
"db_id": "P63001"
},
{
"db_name": "UniProt",
"db_id": "Q6RUV5"
}
]
},
{
"id": "DS.d790.s0.e1",
"type": "compound",
"text": [
"TxA(2"
],
"offsets": [
[
154,
159
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5280497"
}
]
},
{
"id": "DS.d790.s0.e2",
"type": "protein",
"text": [
"GPVI"
],
"offsets": [
[
201,
205
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0C191"
},
{
"db_name": "UniProt",
"db_id": "Q9HCN6"
}
]
}
] | [] | [] | [] |
DS.d791 | 18704543 | [
{
"id": "DS.d791.s0",
"type": "",
"text": [
"LCT 13910 CC genotype is associated with lactose intolerance, a condition often resulting in reduced milk intake."
],
"offsets": [
[
0,
113
]
]
}
] | [
{
"id": "DS.d791.s0.e0",
"type": "protein",
"text": [
"LCT"
],
"offsets": [
[
0,
3
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P09848"
},
{
"db_name": "UniProt",
"db_id": "P09849"
}
]
},
{
"id": "DS.d791.s0.e1",
"type": "compound",
"text": [
"lactose"
],
"offsets": [
[
41,
48
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "294"
},
{
"db_name": "PubChem",
"db_id": "6134"
},
{
"db_name": "PubChem",
"db_id": "84571"
},
{
"db_name": "PubChem",
"db_id": "440995"
}
]
}
] | [] | [] | [
{
"id": "DS.d791.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d791.s0.e1",
"arg2_id": "DS.d791.s0.e0",
"normalized": []
}
] |
DS.d792 | 18704651 | [
{
"id": "DS.d792.s0",
"type": "",
"text": [
"Osteointegration of titanium or its alloy with bone can be greatly improved by calcium phosphate coatings, and further enhanced by an extracellular matrix protein layer such as collagen."
],
"offsets": [
[
0,
186
]
]
}
] | [
{
"id": "DS.d792.s0.e0",
"type": "compound",
"text": [
"titanium"
],
"offsets": [
[
20,
28
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "23963"
}
]
},
{
"id": "DS.d792.s0.e1",
"type": "compound",
"text": [
"calcium phosphate"
],
"offsets": [
[
79,
96
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "24441"
},
{
"db_name": "PubChem",
"db_id": "24456"
},
{
"db_name": "PubChem",
"db_id": "24632"
}
]
},
{
"id": "DS.d792.s0.e2",
"type": "protein",
"text": [
"matrix protein"
],
"offsets": [
[
148,
162
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12705"
},
{
"db_name": "UniProt",
"db_id": "O18559"
},
{
"db_name": "UniProt",
"db_id": "O57299"
},
{
"db_name": "UniProt",
"db_id": "O89341"
},
{
"db_name": "UniProt",
"db_id": "P03314"
},
{
"db_name": "UniProt",
"db_id": "P03344"
},
{
"db_name": "UniProt",
"db_id": "P03419"
},
{
"db_name": "UniProt",
"db_id": "P03426"
},
{
"db_name": "UniProt",
"db_id": "P03519"
},
{
"db_name": "UniProt",
"db_id": "P04876"
},
{
"db_name": "UniProt",
"db_id": "P04888"
},
{
"db_name": "UniProt",
"db_id": "P05769"
},
{
"db_name": "UniProt",
"db_id": "P06157"
},
{
"db_name": "UniProt",
"db_id": "P06166"
},
{
"db_name": "UniProt",
"db_id": "P06446"
},
{
"db_name": "UniProt",
"db_id": "P06502"
},
{
"db_name": "UniProt",
"db_id": "P06503"
},
{
"db_name": "UniProt",
"db_id": "P06935"
},
{
"db_name": "UniProt",
"db_id": "P06942"
},
{
"db_name": "UniProt",
"db_id": "P06943"
},
{
"db_name": "UniProt",
"db_id": "P07564"
},
{
"db_name": "UniProt",
"db_id": "P07720"
},
{
"db_name": "UniProt",
"db_id": "P07873"
},
{
"db_name": "UniProt",
"db_id": "P08325"
},
{
"db_name": "UniProt",
"db_id": "P08671"
},
{
"db_name": "UniProt",
"db_id": "P09732"
},
{
"db_name": "UniProt",
"db_id": "P09866"
},
{
"db_name": "UniProt",
"db_id": "P11206"
},
{
"db_name": "UniProt",
"db_id": "P12446"
},
{
"db_name": "UniProt",
"db_id": "P12823"
},
{
"db_name": "UniProt",
"db_id": "P13616"
},
{
"db_name": "UniProt",
"db_id": "P13844"
},
{
"db_name": "UniProt",
"db_id": "P14335"
},
{
"db_name": "UniProt",
"db_id": "P14336"
},
{
"db_name": "UniProt",
"db_id": "P14340"
},
{
"db_name": "UniProt",
"db_id": "P14403"
},
{
"db_name": "UniProt",
"db_id": "P15200"
},
{
"db_name": "UniProt",
"db_id": "P16287"
},
{
"db_name": "UniProt",
"db_id": "P16628"
},
{
"db_name": "UniProt",
"db_id": "P16629"
},
{
"db_name": "UniProt",
"db_id": "P17748"
},
{
"db_name": "UniProt",
"db_id": "P17763"
},
{
"db_name": "UniProt",
"db_id": "P18356"
},
{
"db_name": "UniProt",
"db_id": "P18611"
},
{
"db_name": "UniProt",
"db_id": "P19110"
},
{
"db_name": "UniProt",
"db_id": "P19692"
},
{
"db_name": "UniProt",
"db_id": "P19718"
},
{
"db_name": "UniProt",
"db_id": "P22046"
},
{
"db_name": "UniProt",
"db_id": "P22338"
},
{
"db_name": "UniProt",
"db_id": "P24266"
},
{
"db_name": "UniProt",
"db_id": "P24615"
},
{
"db_name": "UniProt",
"db_id": "P25058"
},
{
"db_name": "UniProt",
"db_id": "P25182"
},
{
"db_name": "UniProt",
"db_id": "P25223"
},
{
"db_name": "UniProt",
"db_id": "P25224"
},
{
"db_name": "UniProt",
"db_id": "P26034"
},
{
"db_name": "UniProt",
"db_id": "P27019"
},
{
"db_name": "UniProt",
"db_id": "P27020"
},
{
"db_name": "UniProt",
"db_id": "P27287"
},
{
"db_name": "UniProt",
"db_id": "P27395"
},
{
"db_name": "UniProt",
"db_id": "P27663"
},
{
"db_name": "UniProt",
"db_id": "P27910"
},
{
"db_name": "UniProt",
"db_id": "P27912"
},
{
"db_name": "UniProt",
"db_id": "P27913"
},
{
"db_name": "UniProt",
"db_id": "P27915"
},
{
"db_name": "UniProt",
"db_id": "P29165"
},
{
"db_name": "UniProt",
"db_id": "P29837"
},
{
"db_name": "UniProt",
"db_id": "P29838"
},
{
"db_name": "UniProt",
"db_id": "P29983"
},
{
"db_name": "UniProt",
"db_id": "P29984"
},
{
"db_name": "UniProt",
"db_id": "P29990"
},
{
"db_name": "UniProt",
"db_id": "P29991"
},
{
"db_name": "UniProt",
"db_id": "P30026"
},
{
"db_name": "UniProt",
"db_id": "P31035"
},
{
"db_name": "UniProt",
"db_id": "P31620"
},
{
"db_name": "UniProt",
"db_id": "P32886"
},
{
"db_name": "UniProt",
"db_id": "P33478"
},
{
"db_name": "UniProt",
"db_id": "P33482"
},
{
"db_name": "UniProt",
"db_id": "P33515"
},
{
"db_name": "UniProt",
"db_id": "P35947"
},
{
"db_name": "UniProt",
"db_id": "P35976"
},
{
"db_name": "UniProt",
"db_id": "P36355"
},
{
"db_name": "UniProt",
"db_id": "P36356"
},
{
"db_name": "UniProt",
"db_id": "P41358"
},
{
"db_name": "UniProt",
"db_id": "P52637"
},
{
"db_name": "UniProt",
"db_id": "P62683"
},
{
"db_name": "UniProt",
"db_id": "P62684"
},
{
"db_name": "UniProt",
"db_id": "P62685"
},
{
"db_name": "UniProt",
"db_id": "P62689"
},
{
"db_name": "UniProt",
"db_id": "P62690"
},
{
"db_name": "UniProt",
"db_id": "P63117"
},
{
"db_name": "UniProt",
"db_id": "P63126"
},
{
"db_name": "UniProt",
"db_id": "P63128"
},
{
"db_name": "UniProt",
"db_id": "P63130"
},
{
"db_name": "UniProt",
"db_id": "P63145"
},
{
"db_name": "UniProt",
"db_id": "P87577"
},
{
"db_name": "UniProt",
"db_id": "P87889"
},
{
"db_name": "UniProt",
"db_id": "Q01299"
},
{
"db_name": "UniProt",
"db_id": "Q01427"
},
{
"db_name": "UniProt",
"db_id": "Q04538"
},
{
"db_name": "UniProt",
"db_id": "Q074N0"
},
{
"db_name": "UniProt",
"db_id": "Q1X880"
},
{
"db_name": "UniProt",
"db_id": "Q1X881"
},
{
"db_name": "UniProt",
"db_id": "Q66112"
},
{
"db_name": "UniProt",
"db_id": "Q6DV88"
},
{
"db_name": "UniProt",
"db_id": "Q6J3P1"
},
{
"db_name": "UniProt",
"db_id": "Q7LDI9"
},
{
"db_name": "UniProt",
"db_id": "Q84131"
},
{
"db_name": "UniProt",
"db_id": "Q88266"
},
{
"db_name": "UniProt",
"db_id": "Q88428"
},
{
"db_name": "UniProt",
"db_id": "Q89277"
},
{
"db_name": "UniProt",
"db_id": "Q91B74"
},
{
"db_name": "UniProt",
"db_id": "Q96PI4"
},
{
"db_name": "UniProt",
"db_id": "Q98803"
},
{
"db_name": "UniProt",
"db_id": "Q9HDB9"
},
{
"db_name": "UniProt",
"db_id": "Q9IK90"
},
{
"db_name": "UniProt",
"db_id": "Q9JAF2"
},
{
"db_name": "UniProt",
"db_id": "Q9NRZ4"
},
{
"db_name": "UniProt",
"db_id": "Q9UKH8"
},
{
"db_name": "UniProt",
"db_id": "Q9YNA8"
},
{
"db_name": "UniProt",
"db_id": "Q9YRV3"
}
]
}
] | [] | [] | [
{
"id": "DS.d792.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d792.s0.e0",
"arg2_id": "DS.d792.s0.e2",
"normalized": []
}
] |
DS.d793 | 18704653 | [
{
"id": "DS.d793.s0",
"type": "",
"text": [
"Use of tissue transglutaminase and fibronectin to influence osteoblast responses to tricalcium phosphate scaffolds."
],
"offsets": [
[
0,
115
]
]
},
{
"id": "DS.d793.s1",
"type": "",
"text": [
"To explore the possibility of controlling cell interaction with biomaterials, tricalcium phosphate scaffolds were modified using the enzyme tissue transglutaminase (tTgase) in conjunction with fibronectin."
],
"offsets": [
[
116,
321
]
]
}
] | [
{
"id": "DS.d793.s0.e0",
"type": "protein",
"text": [
"tissue transglutaminase"
],
"offsets": [
[
7,
30
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P08587"
},
{
"db_name": "UniProt",
"db_id": "P21980"
},
{
"db_name": "UniProt",
"db_id": "P21981"
},
{
"db_name": "UniProt",
"db_id": "P51176"
},
{
"db_name": "UniProt",
"db_id": "P52181"
},
{
"db_name": "UniProt",
"db_id": "Q01841"
}
]
},
{
"id": "DS.d793.s0.e1",
"type": "protein",
"text": [
"fibronectin"
],
"offsets": [
[
35,
46
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P07589"
},
{
"db_name": "UniProt",
"db_id": "P11722"
},
{
"db_name": "UniProt",
"db_id": "Q28275"
},
{
"db_name": "UniProt",
"db_id": "Q28377"
},
{
"db_name": "UniProt",
"db_id": "Q28749"
},
{
"db_name": "UniProt",
"db_id": "Q91289"
},
{
"db_name": "UniProt",
"db_id": "Q91400"
}
]
},
{
"id": "DS.d793.s0.e2",
"type": "compound",
"text": [
"tricalcium phosphate"
],
"offsets": [
[
84,
104
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "24456"
}
]
},
{
"id": "DS.d793.s1.e0",
"type": "compound",
"text": [
"tricalcium phosphate"
],
"offsets": [
[
194,
214
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "24456"
}
]
},
{
"id": "DS.d793.s1.e1",
"type": "protein",
"text": [
"tissue transglutaminase"
],
"offsets": [
[
256,
279
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P08587"
},
{
"db_name": "UniProt",
"db_id": "P21980"
},
{
"db_name": "UniProt",
"db_id": "P21981"
},
{
"db_name": "UniProt",
"db_id": "P51176"
},
{
"db_name": "UniProt",
"db_id": "P52181"
},
{
"db_name": "UniProt",
"db_id": "Q01841"
}
]
},
{
"id": "DS.d793.s1.e2",
"type": "protein",
"text": [
"fibronectin"
],
"offsets": [
[
309,
320
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P07589"
},
{
"db_name": "UniProt",
"db_id": "P11722"
},
{
"db_name": "UniProt",
"db_id": "Q28275"
},
{
"db_name": "UniProt",
"db_id": "Q28377"
},
{
"db_name": "UniProt",
"db_id": "Q28749"
},
{
"db_name": "UniProt",
"db_id": "Q91289"
},
{
"db_name": "UniProt",
"db_id": "Q91400"
}
]
}
] | [] | [] | [
{
"id": "DS.d793.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d793.s0.e2",
"arg2_id": "DS.d793.s0.e0",
"normalized": []
},
{
"id": "DS.d793.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d793.s0.e2",
"arg2_id": "DS.d793.s0.e1",
"normalized": []
},
{
"id": "DS.d793.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d793.s1.e0",
"arg2_id": "DS.d793.s1.e1",
"normalized": []
},
{
"id": "DS.d793.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d793.s1.e0",
"arg2_id": "DS.d793.s1.e2",
"normalized": []
}
] |
DS.d796 | 18704766 | [
{
"id": "DS.d796.s0",
"type": "",
"text": [
"Four MPTP monkeys received L-DOPA/Benserazide plus CI-1041 an NMDA antagonist selective for NR1/NR2B and four were treated with L-DOPA/Benserazide plus a small dose of cabergoline ; one monkey of each group developed mild dyskinesias at the end of treatment."
],
"offsets": [
[
0,
258
]
]
},
{
"id": "DS.d796.s1",
"type": "",
"text": [
"Hence, MPTP lesion, L-DOPA treatment and prevention of LID with CI-1041 and cabergoline, or reduction with Ro 61-8048 were associated with modulation of NR2B/NMDA glutamate receptors."
],
"offsets": [
[
259,
442
]
]
}
] | [
{
"id": "DS.d796.s0.e0",
"type": "compound",
"text": [
"L-DOPA"
],
"offsets": [
[
27,
33
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6047"
}
]
},
{
"id": "DS.d796.s0.e1",
"type": "compound",
"text": [
"Benserazide"
],
"offsets": [
[
34,
45
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2327"
}
]
},
{
"id": "DS.d796.s0.e2",
"type": "protein",
"text": [
"NR1"
],
"offsets": [
[
92,
95
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P11605"
},
{
"db_name": "UniProt",
"db_id": "P11832"
},
{
"db_name": "UniProt",
"db_id": "P16081"
},
{
"db_name": "UniProt",
"db_id": "P39865"
},
{
"db_name": "UniProt",
"db_id": "Q9SML8"
}
]
},
{
"id": "DS.d796.s0.e3",
"type": "protein",
"text": [
"NR2B"
],
"offsets": [
[
96,
100
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q00960"
},
{
"db_name": "UniProt",
"db_id": "Q01097"
},
{
"db_name": "UniProt",
"db_id": "Q13224"
}
]
},
{
"id": "DS.d796.s0.e4",
"type": "compound",
"text": [
"L-DOPA"
],
"offsets": [
[
128,
134
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6047"
}
]
},
{
"id": "DS.d796.s0.e5",
"type": "compound",
"text": [
"Benserazide"
],
"offsets": [
[
135,
146
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2327"
}
]
},
{
"id": "DS.d796.s0.e6",
"type": "compound",
"text": [
"cabergoline"
],
"offsets": [
[
168,
179
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "54746"
}
]
},
{
"id": "DS.d796.s1.e0",
"type": "compound",
"text": [
"L-DOPA"
],
"offsets": [
[
279,
285
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6047"
}
]
},
{
"id": "DS.d796.s1.e1",
"type": "compound",
"text": [
"cabergoline"
],
"offsets": [
[
335,
346
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "54746"
}
]
},
{
"id": "DS.d796.s1.e2",
"type": "compound",
"text": [
"Ro 61-8048"
],
"offsets": [
[
366,
376
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5282337"
}
]
},
{
"id": "DS.d796.s1.e3",
"type": "protein",
"text": [
"NR2B"
],
"offsets": [
[
412,
416
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q00960"
},
{
"db_name": "UniProt",
"db_id": "Q01097"
},
{
"db_name": "UniProt",
"db_id": "Q13224"
}
]
}
] | [] | [] | [
{
"id": "DS.d796.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d796.s1.e2",
"arg2_id": "DS.d796.s1.e3",
"normalized": []
},
{
"id": "DS.d796.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d796.s1.e0",
"arg2_id": "DS.d796.s1.e3",
"normalized": []
},
{
"id": "DS.d796.s1.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d796.s1.e1",
"arg2_id": "DS.d796.s1.e3",
"normalized": []
}
] |
DS.d797 | 18704940 | [
{
"id": "DS.d797.s0",
"type": "",
"text": [
"MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i)."
],
"offsets": [
[
0,
260
]
]
},
{
"id": "DS.d797.s1",
"type": "",
"text": [
"On the basis of structural studies of MurD complexes, a stepwise catalytic mechanism was proposed that commences with a formation of the acyl-phosphate intermediate, followed by a nucleophilic attack of D-glutamate that, through the formation of a tetrahedral reaction intermediate and subsequent phosphate dissociation, affords the final product, UDP-N-acetyl-muramoyl-L-alanine-D-glutamate (UMAG)."
],
"offsets": [
[
261,
660
]
]
}
] | [
{
"id": "DS.d797.s0.e0",
"type": "protein",
"text": [
"MurD"
],
"offsets": [
[
0,
4
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O06222"
},
{
"db_name": "UniProt",
"db_id": "O07108"
},
{
"db_name": "UniProt",
"db_id": "O07669"
},
{
"db_name": "UniProt",
"db_id": "O25236"
},
{
"db_name": "UniProt",
"db_id": "O51532"
},
{
"db_name": "UniProt",
"db_id": "O67852"
},
{
"db_name": "UniProt",
"db_id": "O83873"
},
{
"db_name": "UniProt",
"db_id": "O84763"
},
{
"db_name": "UniProt",
"db_id": "P0A089"
},
{
"db_name": "UniProt",
"db_id": "P0A090"
},
{
"db_name": "UniProt",
"db_id": "P0A091"
},
{
"db_name": "UniProt",
"db_id": "P0C0D7"
},
{
"db_name": "UniProt",
"db_id": "P0C0D8"
},
{
"db_name": "UniProt",
"db_id": "P14900"
},
{
"db_name": "UniProt",
"db_id": "P45063"
},
{
"db_name": "UniProt",
"db_id": "P57313"
},
{
"db_name": "UniProt",
"db_id": "P57995"
},
{
"db_name": "UniProt",
"db_id": "P73668"
},
{
"db_name": "UniProt",
"db_id": "Q03522"
},
{
"db_name": "UniProt",
"db_id": "Q0SHR9"
},
{
"db_name": "UniProt",
"db_id": "Q0SQ91"
},
{
"db_name": "UniProt",
"db_id": "Q0TLQ1"
},
{
"db_name": "UniProt",
"db_id": "Q0TMJ3"
},
{
"db_name": "UniProt",
"db_id": "Q0VS04"
},
{
"db_name": "UniProt",
"db_id": "Q11GS3"
},
{
"db_name": "UniProt",
"db_id": "Q11RH3"
},
{
"db_name": "UniProt",
"db_id": "Q12EL7"
},
{
"db_name": "UniProt",
"db_id": "Q13TZ0"
},
{
"db_name": "UniProt",
"db_id": "Q14J05"
},
{
"db_name": "UniProt",
"db_id": "Q163I6"
},
{
"db_name": "UniProt",
"db_id": "Q182Y7"
},
{
"db_name": "UniProt",
"db_id": "Q1AVX1"
},
{
"db_name": "UniProt",
"db_id": "Q1BZG5"
},
{
"db_name": "UniProt",
"db_id": "Q1C212"
},
{
"db_name": "UniProt",
"db_id": "Q1CMM9"
},
{
"db_name": "UniProt",
"db_id": "Q1CU35"
},
{
"db_name": "UniProt",
"db_id": "Q1D0S8"
},
{
"db_name": "UniProt",
"db_id": "Q1GAT6"
},
{
"db_name": "UniProt",
"db_id": "Q1GIV4"
},
{
"db_name": "UniProt",
"db_id": "Q1GRX7"
},
{
"db_name": "UniProt",
"db_id": "Q1GYZ9"
},
{
"db_name": "UniProt",
"db_id": "Q1IKG8"
},
{
"db_name": "UniProt",
"db_id": "Q1J147"
},
{
"db_name": "UniProt",
"db_id": "Q1J5S5"
},
{
"db_name": "UniProt",
"db_id": "Q1JAT4"
},
{
"db_name": "UniProt",
"db_id": "Q1JG10"
},
{
"db_name": "UniProt",
"db_id": "Q1JKY4"
},
{
"db_name": "UniProt",
"db_id": "Q1LIM4"
},
{
"db_name": "UniProt",
"db_id": "Q1LSW4"
},
{
"db_name": "UniProt",
"db_id": "Q1ME31"
},
{
"db_name": "UniProt",
"db_id": "Q1MPC1"
},
{
"db_name": "UniProt",
"db_id": "Q1Q883"
},
{
"db_name": "UniProt",
"db_id": "Q1QNU5"
},
{
"db_name": "UniProt",
"db_id": "Q1QVG5"
},
{
"db_name": "UniProt",
"db_id": "Q1RGA7"
},
{
"db_name": "UniProt",
"db_id": "Q1RI52"
},
{
"db_name": "UniProt",
"db_id": "Q1WT99"
},
{
"db_name": "UniProt",
"db_id": "Q216E0"
},
{
"db_name": "UniProt",
"db_id": "Q21MH1"
},
{
"db_name": "UniProt",
"db_id": "Q21SW7"
},
{
"db_name": "UniProt",
"db_id": "Q24TE4"
},
{
"db_name": "UniProt",
"db_id": "Q255W7"
},
{
"db_name": "UniProt",
"db_id": "Q28NN2"
},
{
"db_name": "UniProt",
"db_id": "Q2A1Z9"
},
{
"db_name": "UniProt",
"db_id": "Q2FHQ4"
},
{
"db_name": "UniProt",
"db_id": "Q2FZ92"
},
{
"db_name": "UniProt",
"db_id": "Q2G997"
},
{
"db_name": "UniProt",
"db_id": "Q2IG29"
},
{
"db_name": "UniProt",
"db_id": "Q2IYL0"
},
{
"db_name": "UniProt",
"db_id": "Q2JD52"
},
{
"db_name": "UniProt",
"db_id": "Q2JHP5"
},
{
"db_name": "UniProt",
"db_id": "Q2JVR9"
},
{
"db_name": "UniProt",
"db_id": "Q2K6B9"
},
{
"db_name": "UniProt",
"db_id": "Q2KVF5"
},
{
"db_name": "UniProt",
"db_id": "Q2LR50"
},
{
"db_name": "UniProt",
"db_id": "Q2NVV3"
},
{
"db_name": "UniProt",
"db_id": "Q2P5V2"
},
{
"db_name": "UniProt",
"db_id": "Q2RK81"
},
{
"db_name": "UniProt",
"db_id": "Q2RVU2"
},
{
"db_name": "UniProt",
"db_id": "Q2S530"
},
{
"db_name": "UniProt",
"db_id": "Q2S9Z0"
},
{
"db_name": "UniProt",
"db_id": "Q2SZI5"
},
{
"db_name": "UniProt",
"db_id": "Q2W0H5"
},
{
"db_name": "UniProt",
"db_id": "Q2Y636"
},
{
"db_name": "UniProt",
"db_id": "Q2YM69"
},
{
"db_name": "UniProt",
"db_id": "Q2YXD9"
},
{
"db_name": "UniProt",
"db_id": "Q313Q5"
},
{
"db_name": "UniProt",
"db_id": "Q319C4"
},
{
"db_name": "UniProt",
"db_id": "Q31I61"
},
{
"db_name": "UniProt",
"db_id": "Q31MM2"
},
{
"db_name": "UniProt",
"db_id": "Q326E7"
},
{
"db_name": "UniProt",
"db_id": "Q32K04"
},
{
"db_name": "UniProt",
"db_id": "Q38XM9"
},
{
"db_name": "UniProt",
"db_id": "Q39JX2"
},
{
"db_name": "UniProt",
"db_id": "Q39YM1"
},
{
"db_name": "UniProt",
"db_id": "Q3A2G4"
},
{
"db_name": "UniProt",
"db_id": "Q3AAE4"
},
{
"db_name": "UniProt",
"db_id": "Q3AHP0"
},
{
"db_name": "UniProt",
"db_id": "Q3ANV5"
},
{
"db_name": "UniProt",
"db_id": "Q3AZI5"
},
{
"db_name": "UniProt",
"db_id": "Q3B127"
},
{
"db_name": "UniProt",
"db_id": "Q3BR29"
},
{
"db_name": "UniProt",
"db_id": "Q3IG02"
},
{
"db_name": "UniProt",
"db_id": "Q3J4M6"
},
{
"db_name": "UniProt",
"db_id": "Q3J787"
},
{
"db_name": "UniProt",
"db_id": "Q3JND6"
},
{
"db_name": "UniProt",
"db_id": "Q3K2P4"
},
{
"db_name": "UniProt",
"db_id": "Q3K742"
},
{
"db_name": "UniProt",
"db_id": "Q3KKT4"
},
{
"db_name": "UniProt",
"db_id": "Q3MF19"
},
{
"db_name": "UniProt",
"db_id": "Q3SMH5"
},
{
"db_name": "UniProt",
"db_id": "Q3STT0"
},
{
"db_name": "UniProt",
"db_id": "Q3Z5S1"
},
{
"db_name": "UniProt",
"db_id": "Q46JA8"
},
{
"db_name": "UniProt",
"db_id": "Q46WZ2"
},
{
"db_name": "UniProt",
"db_id": "Q47AA2"
},
{
"db_name": "UniProt",
"db_id": "Q47QX1"
},
{
"db_name": "UniProt",
"db_id": "Q47VQ7"
},
{
"db_name": "UniProt",
"db_id": "Q48EF6"
},
{
"db_name": "UniProt",
"db_id": "Q48SK8"
},
{
"db_name": "UniProt",
"db_id": "Q493Q3"
},
{
"db_name": "UniProt",
"db_id": "Q49WW5"
},
{
"db_name": "UniProt",
"db_id": "Q4FQ21"
},
{
"db_name": "UniProt",
"db_id": "Q4JW97"
},
{
"db_name": "UniProt",
"db_id": "Q4K6J1"
},
{
"db_name": "UniProt",
"db_id": "Q4L5N4"
},
{
"db_name": "UniProt",
"db_id": "Q4QLG0"
},
{
"db_name": "UniProt",
"db_id": "Q4ULT8"
},
{
"db_name": "UniProt",
"db_id": "Q4UWX9"
},
{
"db_name": "UniProt",
"db_id": "Q4ZNY8"
},
{
"db_name": "UniProt",
"db_id": "Q52953"
},
{
"db_name": "UniProt",
"db_id": "Q57C76"
},
{
"db_name": "UniProt",
"db_id": "Q57TD2"
},
{
"db_name": "UniProt",
"db_id": "Q5E2P8"
},
{
"db_name": "UniProt",
"db_id": "Q5F6L6"
},
{
"db_name": "UniProt",
"db_id": "Q5FKV3"
},
{
"db_name": "UniProt",
"db_id": "Q5FUJ7"
},
{
"db_name": "UniProt",
"db_id": "Q5GSC8"
},
{
"db_name": "UniProt",
"db_id": "Q5H2Y1"
},
{
"db_name": "UniProt",
"db_id": "Q5HGP8"
},
{
"db_name": "UniProt",
"db_id": "Q5HQ09"
},
{
"db_name": "UniProt",
"db_id": "Q5HW34"
},
{
"db_name": "UniProt",
"db_id": "Q5L0X7"
},
{
"db_name": "UniProt",
"db_id": "Q5L521"
},
{
"db_name": "UniProt",
"db_id": "Q5LIJ5"
},
{
"db_name": "UniProt",
"db_id": "Q5LU71"
},
{
"db_name": "UniProt",
"db_id": "Q5M0D5"
},
{
"db_name": "UniProt",
"db_id": "Q5M4Y2"
},
{
"db_name": "UniProt",
"db_id": "Q5MZA8"
},
{
"db_name": "UniProt",
"db_id": "Q5NHK3"
},
{
"db_name": "UniProt",
"db_id": "Q5NPA7"
},
{
"db_name": "UniProt",
"db_id": "Q5P6Z4"
},
{
"db_name": "UniProt",
"db_id": "Q5PBH9"
},
{
"db_name": "UniProt",
"db_id": "Q5PDC2"
},
{
"db_name": "UniProt",
"db_id": "Q5R0M3"
},
{
"db_name": "UniProt",
"db_id": "Q5SJD2"
},
{
"db_name": "UniProt",
"db_id": "Q5WFG8"
},
{
"db_name": "UniProt",
"db_id": "Q5WTI5"
},
{
"db_name": "UniProt",
"db_id": "Q5X1S4"
},
{
"db_name": "UniProt",
"db_id": "Q5XB04"
},
{
"db_name": "UniProt",
"db_id": "Q5YYY1"
},
{
"db_name": "UniProt",
"db_id": "Q5ZSA3"
},
{
"db_name": "UniProt",
"db_id": "Q604V5"
},
{
"db_name": "UniProt",
"db_id": "Q62GS5"
},
{
"db_name": "UniProt",
"db_id": "Q636B4"
},
{
"db_name": "UniProt",
"db_id": "Q63QJ5"
},
{
"db_name": "UniProt",
"db_id": "Q64ZL9"
},
{
"db_name": "UniProt",
"db_id": "Q65JY2"
},
{
"db_name": "UniProt",
"db_id": "Q65RY4"
},
{
"db_name": "UniProt",
"db_id": "Q66EK7"
},
{
"db_name": "UniProt",
"db_id": "Q67QM7"
},
{
"db_name": "UniProt",
"db_id": "Q68WW9"
},
{
"db_name": "UniProt",
"db_id": "Q6A9Q4"
},
{
"db_name": "UniProt",
"db_id": "Q6AE62"
},
{
"db_name": "UniProt",
"db_id": "Q6AJ52"
},
{
"db_name": "UniProt",
"db_id": "Q6D0I1"
},
{
"db_name": "UniProt",
"db_id": "Q6FFC2"
},
{
"db_name": "UniProt",
"db_id": "Q6G122"
},
{
"db_name": "UniProt",
"db_id": "Q6G2Q3"
},
{
"db_name": "UniProt",
"db_id": "Q6GA29"
},
{
"db_name": "UniProt",
"db_id": "Q6GHQ2"
},
{
"db_name": "UniProt",
"db_id": "Q6HEQ2"
},
{
"db_name": "UniProt",
"db_id": "Q6LMF4"
},
{
"db_name": "UniProt",
"db_id": "Q6MBS4"
},
{
"db_name": "UniProt",
"db_id": "Q6MIF8"
},
{
"db_name": "UniProt",
"db_id": "Q6N409"
},
{
"db_name": "UniProt",
"db_id": "Q6NGC6"
},
{
"db_name": "UniProt",
"db_id": "Q71XX7"
},
{
"db_name": "UniProt",
"db_id": "Q728U6"
},
{
"db_name": "UniProt",
"db_id": "Q72JQ1"
},
{
"db_name": "UniProt",
"db_id": "Q72NP4"
},
{
"db_name": "UniProt",
"db_id": "Q732F6"
},
{
"db_name": "UniProt",
"db_id": "Q73GT3"
},
{
"db_name": "UniProt",
"db_id": "Q73YQ6"
},
{
"db_name": "UniProt",
"db_id": "Q748D4"
},
{
"db_name": "UniProt",
"db_id": "Q74JY5"
},
{
"db_name": "UniProt",
"db_id": "Q7MNV3"
},
{
"db_name": "UniProt",
"db_id": "Q7MWM5"
},
{
"db_name": "UniProt",
"db_id": "Q7N145"
},
{
"db_name": "UniProt",
"db_id": "Q7NEZ5"
},
{
"db_name": "UniProt",
"db_id": "Q7NPZ7"
},
{
"db_name": "UniProt",
"db_id": "Q7U8T1"
},
{
"db_name": "UniProt",
"db_id": "Q7V0A5"
},
{
"db_name": "UniProt",
"db_id": "Q7V5V5"
},
{
"db_name": "UniProt",
"db_id": "Q7VAM1"
},
{
"db_name": "UniProt",
"db_id": "Q7VEP7"
},
{
"db_name": "UniProt",
"db_id": "Q7VP56"
},
{
"db_name": "UniProt",
"db_id": "Q7VQI9"
},
{
"db_name": "UniProt",
"db_id": "Q7VUQ1"
},
{
"db_name": "UniProt",
"db_id": "Q7W4B2"
},
{
"db_name": "UniProt",
"db_id": "Q7WFS0"
},
{
"db_name": "UniProt",
"db_id": "Q819Q2"
},
{
"db_name": "UniProt",
"db_id": "Q81WC9"
},
{
"db_name": "UniProt",
"db_id": "Q821S1"
},
{
"db_name": "UniProt",
"db_id": "Q82AD8"
},
{
"db_name": "UniProt",
"db_id": "Q82VS5"
},
{
"db_name": "UniProt",
"db_id": "Q83F20"
},
{
"db_name": "UniProt",
"db_id": "Q83GN2"
},
{
"db_name": "UniProt",
"db_id": "Q83HK0"
},
{
"db_name": "UniProt",
"db_id": "Q83MF9"
},
{
"db_name": "UniProt",
"db_id": "Q879A1"
},
{
"db_name": "UniProt",
"db_id": "Q87EA7"
},
{
"db_name": "UniProt",
"db_id": "Q87SG6"
},
{
"db_name": "UniProt",
"db_id": "Q87WY3"
},
{
"db_name": "UniProt",
"db_id": "Q88N78"
},
{
"db_name": "UniProt",
"db_id": "Q88V80"
},
{
"db_name": "UniProt",
"db_id": "Q899G5"
},
{
"db_name": "UniProt",
"db_id": "Q89AQ2"
},
{
"db_name": "UniProt",
"db_id": "Q89FU5"
},
{
"db_name": "UniProt",
"db_id": "Q8A256"
},
{
"db_name": "UniProt",
"db_id": "Q8CSX6"
},
{
"db_name": "UniProt",
"db_id": "Q8D2Z4"
},
{
"db_name": "UniProt",
"db_id": "Q8DEK8"
},
{
"db_name": "UniProt",
"db_id": "Q8DMN8"
},
{
"db_name": "UniProt",
"db_id": "Q8DQM2"
},
{
"db_name": "UniProt",
"db_id": "Q8DVE3"
},
{
"db_name": "UniProt",
"db_id": "Q8E186"
},
{
"db_name": "UniProt",
"db_id": "Q8E6P1"
},
{
"db_name": "UniProt",
"db_id": "Q8E9P6"
},
{
"db_name": "UniProt",
"db_id": "Q8ER50"
},
{
"db_name": "UniProt",
"db_id": "Q8F7V4"
},
{
"db_name": "UniProt",
"db_id": "Q8FL65"
},
{
"db_name": "UniProt",
"db_id": "Q8FNT8"
},
{
"db_name": "UniProt",
"db_id": "Q8FZP2"
},
{
"db_name": "UniProt",
"db_id": "Q8G4Q6"
},
{
"db_name": "UniProt",
"db_id": "Q8K9T2"
},
{
"db_name": "UniProt",
"db_id": "Q8KGD2"
},
{
"db_name": "UniProt",
"db_id": "Q8NX35"
},
{
"db_name": "UniProt",
"db_id": "Q8P063"
},
{
"db_name": "UniProt",
"db_id": "Q8P775"
},
{
"db_name": "UniProt",
"db_id": "Q8PII9"
},
{
"db_name": "UniProt",
"db_id": "Q8R9G4"
},
{
"db_name": "UniProt",
"db_id": "Q8RDQ1"
},
{
"db_name": "UniProt",
"db_id": "Q8UDM6"
},
{
"db_name": "UniProt",
"db_id": "Q8X9Y9"
},
{
"db_name": "UniProt",
"db_id": "Q8XHM4"
},
{
"db_name": "UniProt",
"db_id": "Q8XVI5"
},
{
"db_name": "UniProt",
"db_id": "Q8Y5M1"
},
{
"db_name": "UniProt",
"db_id": "Q8YI68"
},
{
"db_name": "UniProt",
"db_id": "Q8YPS9"
},
{
"db_name": "UniProt",
"db_id": "Q8Z9H0"
},
{
"db_name": "UniProt",
"db_id": "Q8ZIF1"
},
{
"db_name": "UniProt",
"db_id": "Q8ZRU4"
},
{
"db_name": "UniProt",
"db_id": "Q929Y1"
},
{
"db_name": "UniProt",
"db_id": "Q92I60"
},
{
"db_name": "UniProt",
"db_id": "Q97EB9"
},
{
"db_name": "UniProt",
"db_id": "Q97RU8"
},
{
"db_name": "UniProt",
"db_id": "Q98KB1"
},
{
"db_name": "UniProt",
"db_id": "Q9A597"
},
{
"db_name": "UniProt",
"db_id": "Q9CF91"
},
{
"db_name": "UniProt",
"db_id": "Q9CPB0"
},
{
"db_name": "UniProt",
"db_id": "Q9F1N2"
},
{
"db_name": "UniProt",
"db_id": "Q9HVZ9"
},
{
"db_name": "UniProt",
"db_id": "Q9JSZ5"
},
{
"db_name": "UniProt",
"db_id": "Q9K0Y4"
},
{
"db_name": "UniProt",
"db_id": "Q9K9S8"
},
{
"db_name": "UniProt",
"db_id": "Q9KPG5"
},
{
"db_name": "UniProt",
"db_id": "Q9PEB0"
},
{
"db_name": "UniProt",
"db_id": "Q9PI73"
},
{
"db_name": "UniProt",
"db_id": "Q9PLG5"
},
{
"db_name": "UniProt",
"db_id": "Q9RRJ4"
},
{
"db_name": "UniProt",
"db_id": "Q9S2W9"
},
{
"db_name": "UniProt",
"db_id": "Q9WY76"
},
{
"db_name": "UniProt",
"db_id": "Q9Z705"
},
{
"db_name": "UniProt",
"db_id": "Q9ZDC2"
},
{
"db_name": "UniProt",
"db_id": "Q9ZLY0"
}
]
},
{
"id": "DS.d797.s0.e1",
"type": "compound",
"text": [
"UMA"
],
"offsets": [
[
214,
217
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5496796"
}
]
},
{
"id": "DS.d797.s1.e0",
"type": "protein",
"text": [
"MurD"
],
"offsets": [
[
299,
303
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O06222"
},
{
"db_name": "UniProt",
"db_id": "O07108"
},
{
"db_name": "UniProt",
"db_id": "O07669"
},
{
"db_name": "UniProt",
"db_id": "O25236"
},
{
"db_name": "UniProt",
"db_id": "O51532"
},
{
"db_name": "UniProt",
"db_id": "O67852"
},
{
"db_name": "UniProt",
"db_id": "O83873"
},
{
"db_name": "UniProt",
"db_id": "O84763"
},
{
"db_name": "UniProt",
"db_id": "P0A089"
},
{
"db_name": "UniProt",
"db_id": "P0A090"
},
{
"db_name": "UniProt",
"db_id": "P0A091"
},
{
"db_name": "UniProt",
"db_id": "P0C0D7"
},
{
"db_name": "UniProt",
"db_id": "P0C0D8"
},
{
"db_name": "UniProt",
"db_id": "P14900"
},
{
"db_name": "UniProt",
"db_id": "P45063"
},
{
"db_name": "UniProt",
"db_id": "P57313"
},
{
"db_name": "UniProt",
"db_id": "P57995"
},
{
"db_name": "UniProt",
"db_id": "P73668"
},
{
"db_name": "UniProt",
"db_id": "Q03522"
},
{
"db_name": "UniProt",
"db_id": "Q0SHR9"
},
{
"db_name": "UniProt",
"db_id": "Q0SQ91"
},
{
"db_name": "UniProt",
"db_id": "Q0TLQ1"
},
{
"db_name": "UniProt",
"db_id": "Q0TMJ3"
},
{
"db_name": "UniProt",
"db_id": "Q0VS04"
},
{
"db_name": "UniProt",
"db_id": "Q11GS3"
},
{
"db_name": "UniProt",
"db_id": "Q11RH3"
},
{
"db_name": "UniProt",
"db_id": "Q12EL7"
},
{
"db_name": "UniProt",
"db_id": "Q13TZ0"
},
{
"db_name": "UniProt",
"db_id": "Q14J05"
},
{
"db_name": "UniProt",
"db_id": "Q163I6"
},
{
"db_name": "UniProt",
"db_id": "Q182Y7"
},
{
"db_name": "UniProt",
"db_id": "Q1AVX1"
},
{
"db_name": "UniProt",
"db_id": "Q1BZG5"
},
{
"db_name": "UniProt",
"db_id": "Q1C212"
},
{
"db_name": "UniProt",
"db_id": "Q1CMM9"
},
{
"db_name": "UniProt",
"db_id": "Q1CU35"
},
{
"db_name": "UniProt",
"db_id": "Q1D0S8"
},
{
"db_name": "UniProt",
"db_id": "Q1GAT6"
},
{
"db_name": "UniProt",
"db_id": "Q1GIV4"
},
{
"db_name": "UniProt",
"db_id": "Q1GRX7"
},
{
"db_name": "UniProt",
"db_id": "Q1GYZ9"
},
{
"db_name": "UniProt",
"db_id": "Q1IKG8"
},
{
"db_name": "UniProt",
"db_id": "Q1J147"
},
{
"db_name": "UniProt",
"db_id": "Q1J5S5"
},
{
"db_name": "UniProt",
"db_id": "Q1JAT4"
},
{
"db_name": "UniProt",
"db_id": "Q1JG10"
},
{
"db_name": "UniProt",
"db_id": "Q1JKY4"
},
{
"db_name": "UniProt",
"db_id": "Q1LIM4"
},
{
"db_name": "UniProt",
"db_id": "Q1LSW4"
},
{
"db_name": "UniProt",
"db_id": "Q1ME31"
},
{
"db_name": "UniProt",
"db_id": "Q1MPC1"
},
{
"db_name": "UniProt",
"db_id": "Q1Q883"
},
{
"db_name": "UniProt",
"db_id": "Q1QNU5"
},
{
"db_name": "UniProt",
"db_id": "Q1QVG5"
},
{
"db_name": "UniProt",
"db_id": "Q1RGA7"
},
{
"db_name": "UniProt",
"db_id": "Q1RI52"
},
{
"db_name": "UniProt",
"db_id": "Q1WT99"
},
{
"db_name": "UniProt",
"db_id": "Q216E0"
},
{
"db_name": "UniProt",
"db_id": "Q21MH1"
},
{
"db_name": "UniProt",
"db_id": "Q21SW7"
},
{
"db_name": "UniProt",
"db_id": "Q24TE4"
},
{
"db_name": "UniProt",
"db_id": "Q255W7"
},
{
"db_name": "UniProt",
"db_id": "Q28NN2"
},
{
"db_name": "UniProt",
"db_id": "Q2A1Z9"
},
{
"db_name": "UniProt",
"db_id": "Q2FHQ4"
},
{
"db_name": "UniProt",
"db_id": "Q2FZ92"
},
{
"db_name": "UniProt",
"db_id": "Q2G997"
},
{
"db_name": "UniProt",
"db_id": "Q2IG29"
},
{
"db_name": "UniProt",
"db_id": "Q2IYL0"
},
{
"db_name": "UniProt",
"db_id": "Q2JD52"
},
{
"db_name": "UniProt",
"db_id": "Q2JHP5"
},
{
"db_name": "UniProt",
"db_id": "Q2JVR9"
},
{
"db_name": "UniProt",
"db_id": "Q2K6B9"
},
{
"db_name": "UniProt",
"db_id": "Q2KVF5"
},
{
"db_name": "UniProt",
"db_id": "Q2LR50"
},
{
"db_name": "UniProt",
"db_id": "Q2NVV3"
},
{
"db_name": "UniProt",
"db_id": "Q2P5V2"
},
{
"db_name": "UniProt",
"db_id": "Q2RK81"
},
{
"db_name": "UniProt",
"db_id": "Q2RVU2"
},
{
"db_name": "UniProt",
"db_id": "Q2S530"
},
{
"db_name": "UniProt",
"db_id": "Q2S9Z0"
},
{
"db_name": "UniProt",
"db_id": "Q2SZI5"
},
{
"db_name": "UniProt",
"db_id": "Q2W0H5"
},
{
"db_name": "UniProt",
"db_id": "Q2Y636"
},
{
"db_name": "UniProt",
"db_id": "Q2YM69"
},
{
"db_name": "UniProt",
"db_id": "Q2YXD9"
},
{
"db_name": "UniProt",
"db_id": "Q313Q5"
},
{
"db_name": "UniProt",
"db_id": "Q319C4"
},
{
"db_name": "UniProt",
"db_id": "Q31I61"
},
{
"db_name": "UniProt",
"db_id": "Q31MM2"
},
{
"db_name": "UniProt",
"db_id": "Q326E7"
},
{
"db_name": "UniProt",
"db_id": "Q32K04"
},
{
"db_name": "UniProt",
"db_id": "Q38XM9"
},
{
"db_name": "UniProt",
"db_id": "Q39JX2"
},
{
"db_name": "UniProt",
"db_id": "Q39YM1"
},
{
"db_name": "UniProt",
"db_id": "Q3A2G4"
},
{
"db_name": "UniProt",
"db_id": "Q3AAE4"
},
{
"db_name": "UniProt",
"db_id": "Q3AHP0"
},
{
"db_name": "UniProt",
"db_id": "Q3ANV5"
},
{
"db_name": "UniProt",
"db_id": "Q3AZI5"
},
{
"db_name": "UniProt",
"db_id": "Q3B127"
},
{
"db_name": "UniProt",
"db_id": "Q3BR29"
},
{
"db_name": "UniProt",
"db_id": "Q3IG02"
},
{
"db_name": "UniProt",
"db_id": "Q3J4M6"
},
{
"db_name": "UniProt",
"db_id": "Q3J787"
},
{
"db_name": "UniProt",
"db_id": "Q3JND6"
},
{
"db_name": "UniProt",
"db_id": "Q3K2P4"
},
{
"db_name": "UniProt",
"db_id": "Q3K742"
},
{
"db_name": "UniProt",
"db_id": "Q3KKT4"
},
{
"db_name": "UniProt",
"db_id": "Q3MF19"
},
{
"db_name": "UniProt",
"db_id": "Q3SMH5"
},
{
"db_name": "UniProt",
"db_id": "Q3STT0"
},
{
"db_name": "UniProt",
"db_id": "Q3Z5S1"
},
{
"db_name": "UniProt",
"db_id": "Q46JA8"
},
{
"db_name": "UniProt",
"db_id": "Q46WZ2"
},
{
"db_name": "UniProt",
"db_id": "Q47AA2"
},
{
"db_name": "UniProt",
"db_id": "Q47QX1"
},
{
"db_name": "UniProt",
"db_id": "Q47VQ7"
},
{
"db_name": "UniProt",
"db_id": "Q48EF6"
},
{
"db_name": "UniProt",
"db_id": "Q48SK8"
},
{
"db_name": "UniProt",
"db_id": "Q493Q3"
},
{
"db_name": "UniProt",
"db_id": "Q49WW5"
},
{
"db_name": "UniProt",
"db_id": "Q4FQ21"
},
{
"db_name": "UniProt",
"db_id": "Q4JW97"
},
{
"db_name": "UniProt",
"db_id": "Q4K6J1"
},
{
"db_name": "UniProt",
"db_id": "Q4L5N4"
},
{
"db_name": "UniProt",
"db_id": "Q4QLG0"
},
{
"db_name": "UniProt",
"db_id": "Q4ULT8"
},
{
"db_name": "UniProt",
"db_id": "Q4UWX9"
},
{
"db_name": "UniProt",
"db_id": "Q4ZNY8"
},
{
"db_name": "UniProt",
"db_id": "Q52953"
},
{
"db_name": "UniProt",
"db_id": "Q57C76"
},
{
"db_name": "UniProt",
"db_id": "Q57TD2"
},
{
"db_name": "UniProt",
"db_id": "Q5E2P8"
},
{
"db_name": "UniProt",
"db_id": "Q5F6L6"
},
{
"db_name": "UniProt",
"db_id": "Q5FKV3"
},
{
"db_name": "UniProt",
"db_id": "Q5FUJ7"
},
{
"db_name": "UniProt",
"db_id": "Q5GSC8"
},
{
"db_name": "UniProt",
"db_id": "Q5H2Y1"
},
{
"db_name": "UniProt",
"db_id": "Q5HGP8"
},
{
"db_name": "UniProt",
"db_id": "Q5HQ09"
},
{
"db_name": "UniProt",
"db_id": "Q5HW34"
},
{
"db_name": "UniProt",
"db_id": "Q5L0X7"
},
{
"db_name": "UniProt",
"db_id": "Q5L521"
},
{
"db_name": "UniProt",
"db_id": "Q5LIJ5"
},
{
"db_name": "UniProt",
"db_id": "Q5LU71"
},
{
"db_name": "UniProt",
"db_id": "Q5M0D5"
},
{
"db_name": "UniProt",
"db_id": "Q5M4Y2"
},
{
"db_name": "UniProt",
"db_id": "Q5MZA8"
},
{
"db_name": "UniProt",
"db_id": "Q5NHK3"
},
{
"db_name": "UniProt",
"db_id": "Q5NPA7"
},
{
"db_name": "UniProt",
"db_id": "Q5P6Z4"
},
{
"db_name": "UniProt",
"db_id": "Q5PBH9"
},
{
"db_name": "UniProt",
"db_id": "Q5PDC2"
},
{
"db_name": "UniProt",
"db_id": "Q5R0M3"
},
{
"db_name": "UniProt",
"db_id": "Q5SJD2"
},
{
"db_name": "UniProt",
"db_id": "Q5WFG8"
},
{
"db_name": "UniProt",
"db_id": "Q5WTI5"
},
{
"db_name": "UniProt",
"db_id": "Q5X1S4"
},
{
"db_name": "UniProt",
"db_id": "Q5XB04"
},
{
"db_name": "UniProt",
"db_id": "Q5YYY1"
},
{
"db_name": "UniProt",
"db_id": "Q5ZSA3"
},
{
"db_name": "UniProt",
"db_id": "Q604V5"
},
{
"db_name": "UniProt",
"db_id": "Q62GS5"
},
{
"db_name": "UniProt",
"db_id": "Q636B4"
},
{
"db_name": "UniProt",
"db_id": "Q63QJ5"
},
{
"db_name": "UniProt",
"db_id": "Q64ZL9"
},
{
"db_name": "UniProt",
"db_id": "Q65JY2"
},
{
"db_name": "UniProt",
"db_id": "Q65RY4"
},
{
"db_name": "UniProt",
"db_id": "Q66EK7"
},
{
"db_name": "UniProt",
"db_id": "Q67QM7"
},
{
"db_name": "UniProt",
"db_id": "Q68WW9"
},
{
"db_name": "UniProt",
"db_id": "Q6A9Q4"
},
{
"db_name": "UniProt",
"db_id": "Q6AE62"
},
{
"db_name": "UniProt",
"db_id": "Q6AJ52"
},
{
"db_name": "UniProt",
"db_id": "Q6D0I1"
},
{
"db_name": "UniProt",
"db_id": "Q6FFC2"
},
{
"db_name": "UniProt",
"db_id": "Q6G122"
},
{
"db_name": "UniProt",
"db_id": "Q6G2Q3"
},
{
"db_name": "UniProt",
"db_id": "Q6GA29"
},
{
"db_name": "UniProt",
"db_id": "Q6GHQ2"
},
{
"db_name": "UniProt",
"db_id": "Q6HEQ2"
},
{
"db_name": "UniProt",
"db_id": "Q6LMF4"
},
{
"db_name": "UniProt",
"db_id": "Q6MBS4"
},
{
"db_name": "UniProt",
"db_id": "Q6MIF8"
},
{
"db_name": "UniProt",
"db_id": "Q6N409"
},
{
"db_name": "UniProt",
"db_id": "Q6NGC6"
},
{
"db_name": "UniProt",
"db_id": "Q71XX7"
},
{
"db_name": "UniProt",
"db_id": "Q728U6"
},
{
"db_name": "UniProt",
"db_id": "Q72JQ1"
},
{
"db_name": "UniProt",
"db_id": "Q72NP4"
},
{
"db_name": "UniProt",
"db_id": "Q732F6"
},
{
"db_name": "UniProt",
"db_id": "Q73GT3"
},
{
"db_name": "UniProt",
"db_id": "Q73YQ6"
},
{
"db_name": "UniProt",
"db_id": "Q748D4"
},
{
"db_name": "UniProt",
"db_id": "Q74JY5"
},
{
"db_name": "UniProt",
"db_id": "Q7MNV3"
},
{
"db_name": "UniProt",
"db_id": "Q7MWM5"
},
{
"db_name": "UniProt",
"db_id": "Q7N145"
},
{
"db_name": "UniProt",
"db_id": "Q7NEZ5"
},
{
"db_name": "UniProt",
"db_id": "Q7NPZ7"
},
{
"db_name": "UniProt",
"db_id": "Q7U8T1"
},
{
"db_name": "UniProt",
"db_id": "Q7V0A5"
},
{
"db_name": "UniProt",
"db_id": "Q7V5V5"
},
{
"db_name": "UniProt",
"db_id": "Q7VAM1"
},
{
"db_name": "UniProt",
"db_id": "Q7VEP7"
},
{
"db_name": "UniProt",
"db_id": "Q7VP56"
},
{
"db_name": "UniProt",
"db_id": "Q7VQI9"
},
{
"db_name": "UniProt",
"db_id": "Q7VUQ1"
},
{
"db_name": "UniProt",
"db_id": "Q7W4B2"
},
{
"db_name": "UniProt",
"db_id": "Q7WFS0"
},
{
"db_name": "UniProt",
"db_id": "Q819Q2"
},
{
"db_name": "UniProt",
"db_id": "Q81WC9"
},
{
"db_name": "UniProt",
"db_id": "Q821S1"
},
{
"db_name": "UniProt",
"db_id": "Q82AD8"
},
{
"db_name": "UniProt",
"db_id": "Q82VS5"
},
{
"db_name": "UniProt",
"db_id": "Q83F20"
},
{
"db_name": "UniProt",
"db_id": "Q83GN2"
},
{
"db_name": "UniProt",
"db_id": "Q83HK0"
},
{
"db_name": "UniProt",
"db_id": "Q83MF9"
},
{
"db_name": "UniProt",
"db_id": "Q879A1"
},
{
"db_name": "UniProt",
"db_id": "Q87EA7"
},
{
"db_name": "UniProt",
"db_id": "Q87SG6"
},
{
"db_name": "UniProt",
"db_id": "Q87WY3"
},
{
"db_name": "UniProt",
"db_id": "Q88N78"
},
{
"db_name": "UniProt",
"db_id": "Q88V80"
},
{
"db_name": "UniProt",
"db_id": "Q899G5"
},
{
"db_name": "UniProt",
"db_id": "Q89AQ2"
},
{
"db_name": "UniProt",
"db_id": "Q89FU5"
},
{
"db_name": "UniProt",
"db_id": "Q8A256"
},
{
"db_name": "UniProt",
"db_id": "Q8CSX6"
},
{
"db_name": "UniProt",
"db_id": "Q8D2Z4"
},
{
"db_name": "UniProt",
"db_id": "Q8DEK8"
},
{
"db_name": "UniProt",
"db_id": "Q8DMN8"
},
{
"db_name": "UniProt",
"db_id": "Q8DQM2"
},
{
"db_name": "UniProt",
"db_id": "Q8DVE3"
},
{
"db_name": "UniProt",
"db_id": "Q8E186"
},
{
"db_name": "UniProt",
"db_id": "Q8E6P1"
},
{
"db_name": "UniProt",
"db_id": "Q8E9P6"
},
{
"db_name": "UniProt",
"db_id": "Q8ER50"
},
{
"db_name": "UniProt",
"db_id": "Q8F7V4"
},
{
"db_name": "UniProt",
"db_id": "Q8FL65"
},
{
"db_name": "UniProt",
"db_id": "Q8FNT8"
},
{
"db_name": "UniProt",
"db_id": "Q8FZP2"
},
{
"db_name": "UniProt",
"db_id": "Q8G4Q6"
},
{
"db_name": "UniProt",
"db_id": "Q8K9T2"
},
{
"db_name": "UniProt",
"db_id": "Q8KGD2"
},
{
"db_name": "UniProt",
"db_id": "Q8NX35"
},
{
"db_name": "UniProt",
"db_id": "Q8P063"
},
{
"db_name": "UniProt",
"db_id": "Q8P775"
},
{
"db_name": "UniProt",
"db_id": "Q8PII9"
},
{
"db_name": "UniProt",
"db_id": "Q8R9G4"
},
{
"db_name": "UniProt",
"db_id": "Q8RDQ1"
},
{
"db_name": "UniProt",
"db_id": "Q8UDM6"
},
{
"db_name": "UniProt",
"db_id": "Q8X9Y9"
},
{
"db_name": "UniProt",
"db_id": "Q8XHM4"
},
{
"db_name": "UniProt",
"db_id": "Q8XVI5"
},
{
"db_name": "UniProt",
"db_id": "Q8Y5M1"
},
{
"db_name": "UniProt",
"db_id": "Q8YI68"
},
{
"db_name": "UniProt",
"db_id": "Q8YPS9"
},
{
"db_name": "UniProt",
"db_id": "Q8Z9H0"
},
{
"db_name": "UniProt",
"db_id": "Q8ZIF1"
},
{
"db_name": "UniProt",
"db_id": "Q8ZRU4"
},
{
"db_name": "UniProt",
"db_id": "Q929Y1"
},
{
"db_name": "UniProt",
"db_id": "Q92I60"
},
{
"db_name": "UniProt",
"db_id": "Q97EB9"
},
{
"db_name": "UniProt",
"db_id": "Q97RU8"
},
{
"db_name": "UniProt",
"db_id": "Q98KB1"
},
{
"db_name": "UniProt",
"db_id": "Q9A597"
},
{
"db_name": "UniProt",
"db_id": "Q9CF91"
},
{
"db_name": "UniProt",
"db_id": "Q9CPB0"
},
{
"db_name": "UniProt",
"db_id": "Q9F1N2"
},
{
"db_name": "UniProt",
"db_id": "Q9HVZ9"
},
{
"db_name": "UniProt",
"db_id": "Q9JSZ5"
},
{
"db_name": "UniProt",
"db_id": "Q9K0Y4"
},
{
"db_name": "UniProt",
"db_id": "Q9K9S8"
},
{
"db_name": "UniProt",
"db_id": "Q9KPG5"
},
{
"db_name": "UniProt",
"db_id": "Q9PEB0"
},
{
"db_name": "UniProt",
"db_id": "Q9PI73"
},
{
"db_name": "UniProt",
"db_id": "Q9PLG5"
},
{
"db_name": "UniProt",
"db_id": "Q9RRJ4"
},
{
"db_name": "UniProt",
"db_id": "Q9S2W9"
},
{
"db_name": "UniProt",
"db_id": "Q9WY76"
},
{
"db_name": "UniProt",
"db_id": "Q9Z705"
},
{
"db_name": "UniProt",
"db_id": "Q9ZDC2"
},
{
"db_name": "UniProt",
"db_id": "Q9ZLY0"
}
]
},
{
"id": "DS.d797.s1.e2",
"type": "compound",
"text": [
"D-glutamate"
],
"offsets": [
[
464,
475
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "23327"
}
]
}
] | [] | [] | [
{
"id": "DS.d797.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d797.s0.e1",
"arg2_id": "DS.d797.s0.e0",
"normalized": []
},
{
"id": "DS.d797.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d797.s1.e2",
"arg2_id": "DS.d797.s1.e0",
"normalized": []
}
] |
DS.d798 | 18704946 | [
{
"id": "DS.d798.s0",
"type": "",
"text": [
"Although the overall amino acid identity between SERTs and the LeuT(Aa) is only 17%, it increases to above 50% in the first shell of the putative 5-HT binding site, allowing de novo computational docking of tryptamine derivatives in atomic detail."
],
"offsets": [
[
0,
247
]
]
}
] | [
{
"id": "DS.d798.s0.e0",
"type": "protein",
"text": [
"SERTs"
],
"offsets": [
[
49,
54
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P31645"
},
{
"db_name": "UniProt",
"db_id": "Q9XT49"
}
]
},
{
"id": "DS.d798.s0.e1",
"type": "compound",
"text": [
"tryptamine"
],
"offsets": [
[
207,
217
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1150"
}
]
}
] | [] | [] | [] |
DS.d799 | 18704953 | [
{
"id": "DS.d799.s0",
"type": "",
"text": [
"Mal-sCT, prepared by conjugating sCT via thio-ether bonds with aqueous-soluble palmitic acid derivative at Cys 1 and Cys 7, was reacted with mPEG-succinimide (mPEG-Suc, 5 kDa)."
],
"offsets": [
[
0,
176
]
]
}
] | [
{
"id": "DS.d799.s0.e0",
"type": "protein",
"text": [
"sCT"
],
"offsets": [
[
4,
7
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P56862"
}
]
},
{
"id": "DS.d799.s0.e1",
"type": "protein",
"text": [
"sCT"
],
"offsets": [
[
33,
36
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P56862"
}
]
},
{
"id": "DS.d799.s0.e3",
"type": "compound",
"text": [
"palmitic acid"
],
"offsets": [
[
79,
92
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "985"
}
]
},
{
"id": "DS.d799.s0.e4",
"type": "compound",
"text": [
"mPEG"
],
"offsets": [
[
141,
145
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "8019"
}
]
},
{
"id": "DS.d799.s0.e5",
"type": "compound",
"text": [
"succinimide"
],
"offsets": [
[
146,
157
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "11439"
}
]
},
{
"id": "DS.d799.s0.e6",
"type": "compound",
"text": [
"mPEG"
],
"offsets": [
[
159,
163
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "8019"
}
]
}
] | [] | [] | [
{
"id": "DS.d799.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d799.s0.e5",
"arg2_id": "DS.d799.s0.e0",
"normalized": []
},
{
"id": "DS.d799.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d799.s0.e3",
"arg2_id": "DS.d799.s0.e0",
"normalized": []
},
{
"id": "DS.d799.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d799.s0.e4",
"arg2_id": "DS.d799.s0.e0",
"normalized": []
}
] |
DS.d800 | 18704955 | [
{
"id": "DS.d800.s0",
"type": "",
"text": [
"Our findings suggest that GLP-1 substituted with a PEG of an appropriate Mw at Lys (34) could be used as a promising type 2 anti-diabetic agent to timely control postprandial glucose levels."
],
"offsets": [
[
0,
190
]
]
}
] | [
{
"id": "DS.d800.s0.e0",
"type": "protein",
"text": [
"GLP-1"
],
"offsets": [
[
26,
31
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12956"
},
{
"db_name": "UniProt",
"db_id": "P01272"
},
{
"db_name": "UniProt",
"db_id": "P01273"
},
{
"db_name": "UniProt",
"db_id": "P01274"
},
{
"db_name": "UniProt",
"db_id": "P01275"
},
{
"db_name": "UniProt",
"db_id": "P05110"
},
{
"db_name": "UniProt",
"db_id": "P06883"
},
{
"db_name": "UniProt",
"db_id": "P22890"
},
{
"db_name": "UniProt",
"db_id": "P29794"
},
{
"db_name": "UniProt",
"db_id": "P55095"
},
{
"db_name": "UniProt",
"db_id": "P68259"
},
{
"db_name": "UniProt",
"db_id": "Q06605"
},
{
"db_name": "UniProt",
"db_id": "Q8MJ25"
}
]
},
{
"id": "DS.d800.s0.e1",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
175,
182
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
}
] | [] | [] | [
{
"id": "DS.d800.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d800.s0.e1",
"arg2_id": "DS.d800.s0.e0",
"normalized": []
}
] |
DS.d801 | 18706130 | [
{
"id": "DS.d801.s0",
"type": "",
"text": [
"The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats."
],
"offsets": [
[
0,
202
]
]
}
] | [
{
"id": "DS.d801.s0.e0",
"type": "compound",
"text": [
"agomelatine"
],
"offsets": [
[
19,
30
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "82148"
}
]
},
{
"id": "DS.d801.s0.e1",
"type": "protein",
"text": [
"NCAM"
],
"offsets": [
[
158,
162
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P13591"
},
{
"db_name": "UniProt",
"db_id": "P13592"
},
{
"db_name": "UniProt",
"db_id": "P31836"
}
]
}
] | [] | [] | [
{
"id": "DS.d801.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d801.s0.e0",
"arg2_id": "DS.d801.s0.e1",
"normalized": []
}
] |
DS.d802 | 18706695 | [
{
"id": "DS.d802.s0",
"type": "",
"text": [
"Phosphatase activity was also inhibited for all the soils treated with triclosan (from 0.1 to 50mg/kg dry soil), but a declining inhibition was observed after 2 days of incubation."
],
"offsets": [
[
0,
180
]
]
}
] | [
{
"id": "DS.d802.s0.e0",
"type": "protein",
"text": [
"Phosphatase"
],
"offsets": [
[
0,
11
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P06961"
},
{
"db_name": "UniProt",
"db_id": "P45269"
},
{
"db_name": "UniProt",
"db_id": "Q57JQ5"
},
{
"db_name": "UniProt",
"db_id": "Q5E2K7"
},
{
"db_name": "UniProt",
"db_id": "Q5F8K9"
},
{
"db_name": "UniProt",
"db_id": "Q5P3T0"
},
{
"db_name": "UniProt",
"db_id": "Q5PC82"
},
{
"db_name": "UniProt",
"db_id": "Q5WT58"
},
{
"db_name": "UniProt",
"db_id": "Q5X1E5"
},
{
"db_name": "UniProt",
"db_id": "Q5ZRX9"
},
{
"db_name": "UniProt",
"db_id": "Q60CQ4"
},
{
"db_name": "UniProt",
"db_id": "Q62EU1"
},
{
"db_name": "UniProt",
"db_id": "Q63YC3"
},
{
"db_name": "UniProt",
"db_id": "Q65Q41"
},
{
"db_name": "UniProt",
"db_id": "Q665U9"
},
{
"db_name": "UniProt",
"db_id": "Q6D160"
},
{
"db_name": "UniProt",
"db_id": "Q6FA38"
},
{
"db_name": "UniProt",
"db_id": "Q6LV05"
},
{
"db_name": "UniProt",
"db_id": "Q7M7K5"
},
{
"db_name": "UniProt",
"db_id": "Q7MAZ9"
},
{
"db_name": "UniProt",
"db_id": "Q7MBF4"
},
{
"db_name": "UniProt",
"db_id": "Q821A6"
},
{
"db_name": "UniProt",
"db_id": "Q82U82"
},
{
"db_name": "UniProt",
"db_id": "Q87DS9"
},
{
"db_name": "UniProt",
"db_id": "Q87SK9"
},
{
"db_name": "UniProt",
"db_id": "Q88A53"
},
{
"db_name": "UniProt",
"db_id": "Q88QU2"
},
{
"db_name": "UniProt",
"db_id": "Q8CWL6"
},
{
"db_name": "UniProt",
"db_id": "Q8CXX6"
},
{
"db_name": "UniProt",
"db_id": "Q8P5D4"
},
{
"db_name": "UniProt",
"db_id": "Q8PPG9"
},
{
"db_name": "UniProt",
"db_id": "Q8XBL4"
},
{
"db_name": "UniProt",
"db_id": "Q8Y395"
},
{
"db_name": "UniProt",
"db_id": "Q8Z3M9"
},
{
"db_name": "UniProt",
"db_id": "Q8ZI64"
},
{
"db_name": "UniProt",
"db_id": "Q8ZLY4"
},
{
"db_name": "UniProt",
"db_id": "Q9CP21"
},
{
"db_name": "UniProt",
"db_id": "Q9I5V3"
},
{
"db_name": "UniProt",
"db_id": "Q9JUB2"
},
{
"db_name": "UniProt",
"db_id": "Q9JZ88"
},
{
"db_name": "UniProt",
"db_id": "Q9KPC6"
},
{
"db_name": "UniProt",
"db_id": "Q9L7A3"
},
{
"db_name": "UniProt",
"db_id": "Q9PDL7"
}
]
},
{
"id": "DS.d802.s0.e1",
"type": "compound",
"text": [
"triclosan"
],
"offsets": [
[
71,
80
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5564"
}
]
}
] | [] | [] | [
{
"id": "DS.d802.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d802.s0.e1",
"arg2_id": "DS.d802.s0.e0",
"normalized": []
}
] |
DS.d804 | 18706940 | [
{
"id": "DS.d804.s0",
"type": "",
"text": [
"The magnitude of autophagosome formation is tightly regulated by intracellular and extracellular amino acid concentrations and ATP levels via signaling pathways that include the nutrient sensing kinase TOR."
],
"offsets": [
[
0,
206
]
]
}
] | [
{
"id": "DS.d804.s0.e0",
"type": "compound",
"text": [
"ATP"
],
"offsets": [
[
127,
130
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5957"
}
]
},
{
"id": "DS.d804.s0.e1",
"type": "protein",
"text": [
"TOR"
],
"offsets": [
[
202,
205
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P51450"
}
]
}
] | [] | [] | [
{
"id": "DS.d804.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d804.s0.e0",
"arg2_id": "DS.d804.s0.e1",
"normalized": []
}
] |
DS.d805 | 18707755 | [
{
"id": "DS.d805.s0",
"type": "",
"text": [
"Normoglycemic (4.72 mmol/L), moderate (11.1 mmol/L) or high grade (16.7 mmol/L) glucose clamps were maintained for 6 hours by infusion of glucose, insulin and somatostatin."
],
"offsets": [
[
0,
172
]
]
}
] | [
{
"id": "DS.d805.s0.e0",
"type": "compound",
"text": [
"L) glucose"
],
"offsets": [
[
77,
87
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2724488"
},
{
"db_name": "PubChem",
"db_id": "10954115"
}
]
},
{
"id": "DS.d805.s0.e1",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
80,
87
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d805.s0.e2",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
147,
154
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d805.s0.e3",
"type": "compound",
"text": [
"somatostatin"
],
"offsets": [
[
159,
171
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "16129681"
},
{
"db_name": "PubChem",
"db_id": "16129706"
}
]
}
] | [] | [] | [] |
DS.d806 | 18708066 | [
{
"id": "DS.d806.s0",
"type": "",
"text": [
"or=6 ng/ml) was associated with increased expression of mrp-1 and pgp-1 and decreased glutathione, while higher level resistance (10 ng/ml) was primarily associated with the increased expression of P-glycoproteins."
],
"offsets": [
[
0,
214
]
]
}
] | [
{
"id": "DS.d806.s0.e0",
"type": "protein",
"text": [
"mrp"
],
"offsets": [
[
56,
59
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O24999"
},
{
"db_name": "UniProt",
"db_id": "O35379"
},
{
"db_name": "UniProt",
"db_id": "O66946"
},
{
"db_name": "UniProt",
"db_id": "P0AF08"
},
{
"db_name": "UniProt",
"db_id": "P0AF09"
},
{
"db_name": "UniProt",
"db_id": "P28667"
},
{
"db_name": "UniProt",
"db_id": "P32653"
},
{
"db_name": "UniProt",
"db_id": "P45135"
},
{
"db_name": "UniProt",
"db_id": "P50863"
},
{
"db_name": "UniProt",
"db_id": "P53381"
},
{
"db_name": "UniProt",
"db_id": "P53382"
},
{
"db_name": "UniProt",
"db_id": "P53383"
},
{
"db_name": "UniProt",
"db_id": "P65441"
},
{
"db_name": "UniProt",
"db_id": "P65442"
},
{
"db_name": "UniProt",
"db_id": "Q92JA4"
},
{
"db_name": "UniProt",
"db_id": "Q9RVM9"
},
{
"db_name": "UniProt",
"db_id": "Q9ZE27"
},
{
"db_name": "UniProt",
"db_id": "Q9ZMM5"
}
]
},
{
"id": "DS.d806.s0.e1",
"type": "protein",
"text": [
"pgp-1"
],
"offsets": [
[
66,
71
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P34712"
}
]
},
{
"id": "DS.d806.s0.e2",
"type": "compound",
"text": [
"glutathione"
],
"offsets": [
[
86,
97
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
},
{
"id": "DS.d806.s0.e3",
"type": "protein",
"text": [
"glycoproteins"
],
"offsets": [
[
200,
213
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P08163"
}
]
}
] | [] | [] | [] |
DS.d807 | 18708157 | [
{
"id": "DS.d807.s0",
"type": "",
"text": [
"Co(2+) also induces the release of the pro-apoptotic factors, cytochrome c and AIF."
],
"offsets": [
[
0,
83
]
]
},
{
"id": "DS.d807.s1",
"type": "",
"text": [
"Incubation of rat hepatocyte primary cultures with Co(2+) results in apoptosis induction with caspase activation and increased level of expression of HIF-1alpha."
],
"offsets": [
[
84,
245
]
]
}
] | [
{
"id": "DS.d807.s0.e0",
"type": "compound",
"text": [
"Co(2"
],
"offsets": [
[
0,
4
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "104729"
}
]
},
{
"id": "DS.d807.s0.e1",
"type": "protein",
"text": [
"cytochrome c"
],
"offsets": [
[
62,
74
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O07091"
},
{
"db_name": "UniProt",
"db_id": "O13393"
},
{
"db_name": "UniProt",
"db_id": "O22642"
},
{
"db_name": "UniProt",
"db_id": "O93863"
},
{
"db_name": "UniProt",
"db_id": "P00002"
},
{
"db_name": "UniProt",
"db_id": "P00003"
},
{
"db_name": "UniProt",
"db_id": "P00004"
},
{
"db_name": "UniProt",
"db_id": "P00007"
},
{
"db_name": "UniProt",
"db_id": "P00008"
},
{
"db_name": "UniProt",
"db_id": "P00011"
},
{
"db_name": "UniProt",
"db_id": "P00012"
},
{
"db_name": "UniProt",
"db_id": "P00013"
},
{
"db_name": "UniProt",
"db_id": "P00014"
},
{
"db_name": "UniProt",
"db_id": "P00017"
},
{
"db_name": "UniProt",
"db_id": "P00018"
},
{
"db_name": "UniProt",
"db_id": "P00019"
},
{
"db_name": "UniProt",
"db_id": "P00020"
},
{
"db_name": "UniProt",
"db_id": "P00021"
},
{
"db_name": "UniProt",
"db_id": "P00022"
},
{
"db_name": "UniProt",
"db_id": "P00024"
},
{
"db_name": "UniProt",
"db_id": "P00025"
},
{
"db_name": "UniProt",
"db_id": "P00027"
},
{
"db_name": "UniProt",
"db_id": "P00028"
},
{
"db_name": "UniProt",
"db_id": "P00029"
},
{
"db_name": "UniProt",
"db_id": "P00030"
},
{
"db_name": "UniProt",
"db_id": "P00031"
},
{
"db_name": "UniProt",
"db_id": "P00032"
},
{
"db_name": "UniProt",
"db_id": "P00035"
},
{
"db_name": "UniProt",
"db_id": "P00036"
},
{
"db_name": "UniProt",
"db_id": "P00037"
},
{
"db_name": "UniProt",
"db_id": "P00038"
},
{
"db_name": "UniProt",
"db_id": "P00039"
},
{
"db_name": "UniProt",
"db_id": "P00040"
},
{
"db_name": "UniProt",
"db_id": "P00041"
},
{
"db_name": "UniProt",
"db_id": "P00042"
},
{
"db_name": "UniProt",
"db_id": "P00043"
},
{
"db_name": "UniProt",
"db_id": "P00046"
},
{
"db_name": "UniProt",
"db_id": "P00047"
},
{
"db_name": "UniProt",
"db_id": "P00048"
},
{
"db_name": "UniProt",
"db_id": "P00049"
},
{
"db_name": "UniProt",
"db_id": "P00051"
},
{
"db_name": "UniProt",
"db_id": "P00052"
},
{
"db_name": "UniProt",
"db_id": "P00053"
},
{
"db_name": "UniProt",
"db_id": "P00054"
},
{
"db_name": "UniProt",
"db_id": "P00055"
},
{
"db_name": "UniProt",
"db_id": "P00056"
},
{
"db_name": "UniProt",
"db_id": "P00057"
},
{
"db_name": "UniProt",
"db_id": "P00058"
},
{
"db_name": "UniProt",
"db_id": "P00059"
},
{
"db_name": "UniProt",
"db_id": "P00060"
},
{
"db_name": "UniProt",
"db_id": "P00061"
},
{
"db_name": "UniProt",
"db_id": "P00062"
},
{
"db_name": "UniProt",
"db_id": "P00063"
},
{
"db_name": "UniProt",
"db_id": "P00064"
},
{
"db_name": "UniProt",
"db_id": "P00065"
},
{
"db_name": "UniProt",
"db_id": "P00066"
},
{
"db_name": "UniProt",
"db_id": "P00067"
},
{
"db_name": "UniProt",
"db_id": "P00068"
},
{
"db_name": "UniProt",
"db_id": "P00069"
},
{
"db_name": "UniProt",
"db_id": "P00070"
},
{
"db_name": "UniProt",
"db_id": "P00071"
},
{
"db_name": "UniProt",
"db_id": "P00072"
},
{
"db_name": "UniProt",
"db_id": "P00073"
},
{
"db_name": "UniProt",
"db_id": "P00074"
},
{
"db_name": "UniProt",
"db_id": "P00075"
},
{
"db_name": "UniProt",
"db_id": "P00076"
},
{
"db_name": "UniProt",
"db_id": "P00077"
},
{
"db_name": "UniProt",
"db_id": "P00078"
},
{
"db_name": "UniProt",
"db_id": "P00079"
},
{
"db_name": "UniProt",
"db_id": "P12831"
},
{
"db_name": "UniProt",
"db_id": "P15451"
},
{
"db_name": "UniProt",
"db_id": "P18822"
},
{
"db_name": "UniProt",
"db_id": "P19681"
},
{
"db_name": "UniProt",
"db_id": "P19974"
},
{
"db_name": "UniProt",
"db_id": "P21665"
},
{
"db_name": "UniProt",
"db_id": "P22342"
},
{
"db_name": "UniProt",
"db_id": "P25400"
},
{
"db_name": "UniProt",
"db_id": "P29380"
},
{
"db_name": "UniProt",
"db_id": "P32556"
},
{
"db_name": "UniProt",
"db_id": "P38091"
},
{
"db_name": "UniProt",
"db_id": "P53698"
},
{
"db_name": "UniProt",
"db_id": "P56205"
},
{
"db_name": "UniProt",
"db_id": "P59218"
},
{
"db_name": "UniProt",
"db_id": "P62772"
},
{
"db_name": "UniProt",
"db_id": "P62773"
},
{
"db_name": "UniProt",
"db_id": "P62894"
},
{
"db_name": "UniProt",
"db_id": "P62895"
},
{
"db_name": "UniProt",
"db_id": "P62896"
},
{
"db_name": "UniProt",
"db_id": "P67881"
},
{
"db_name": "UniProt",
"db_id": "P67882"
},
{
"db_name": "UniProt",
"db_id": "P68096"
},
{
"db_name": "UniProt",
"db_id": "P68097"
},
{
"db_name": "UniProt",
"db_id": "P68098"
},
{
"db_name": "UniProt",
"db_id": "P68099"
},
{
"db_name": "UniProt",
"db_id": "P68100"
},
{
"db_name": "UniProt",
"db_id": "P68517"
},
{
"db_name": "UniProt",
"db_id": "P68518"
},
{
"db_name": "UniProt",
"db_id": "P68519"
},
{
"db_name": "UniProt",
"db_id": "P81280"
},
{
"db_name": "UniProt",
"db_id": "P81459"
},
{
"db_name": "UniProt",
"db_id": "P99998"
},
{
"db_name": "UniProt",
"db_id": "P99999"
},
{
"db_name": "UniProt",
"db_id": "Q41346"
},
{
"db_name": "UniProt",
"db_id": "Q4HVX7"
},
{
"db_name": "UniProt",
"db_id": "Q52V08"
},
{
"db_name": "UniProt",
"db_id": "Q52V09"
},
{
"db_name": "UniProt",
"db_id": "Q52V10"
},
{
"db_name": "UniProt",
"db_id": "Q5RFH4"
},
{
"db_name": "UniProt",
"db_id": "Q640U4"
},
{
"db_name": "UniProt",
"db_id": "Q6C9Q0"
},
{
"db_name": "UniProt",
"db_id": "Q6IQM2"
},
{
"db_name": "UniProt",
"db_id": "Q6Q4H8"
},
{
"db_name": "UniProt",
"db_id": "Q6QLW4"
},
{
"db_name": "UniProt",
"db_id": "Q6WUX8"
},
{
"db_name": "UniProt",
"db_id": "Q753F4"
},
{
"db_name": "UniProt",
"db_id": "Q7YR71"
},
{
"db_name": "UniProt",
"db_id": "Q96VP3"
}
]
},
{
"id": "DS.d807.s0.e2",
"type": "protein",
"text": [
"AIF"
],
"offsets": [
[
79,
82
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O95831"
}
]
},
{
"id": "DS.d807.s1.e0",
"type": "compound",
"text": [
"Co(2"
],
"offsets": [
[
135,
139
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "104729"
}
]
},
{
"id": "DS.d807.s1.e1",
"type": "protein",
"text": [
"HIF-1alpha"
],
"offsets": [
[
234,
244
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35800"
},
{
"db_name": "UniProt",
"db_id": "Q0PGG7"
},
{
"db_name": "UniProt",
"db_id": "Q16665"
},
{
"db_name": "UniProt",
"db_id": "Q309Z6"
},
{
"db_name": "UniProt",
"db_id": "Q61221"
},
{
"db_name": "UniProt",
"db_id": "Q98SW2"
},
{
"db_name": "UniProt",
"db_id": "Q9I8A9"
},
{
"db_name": "UniProt",
"db_id": "Q9XTA5"
},
{
"db_name": "UniProt",
"db_id": "Q9YIB9"
}
]
}
] | [] | [] | [
{
"id": "DS.d807.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d807.s0.e0",
"arg2_id": "DS.d807.s0.e1",
"normalized": []
},
{
"id": "DS.d807.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d807.s0.e0",
"arg2_id": "DS.d807.s0.e2",
"normalized": []
},
{
"id": "DS.d807.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d807.s1.e0",
"arg2_id": "DS.d807.s1.e1",
"normalized": []
}
] |
DS.d808 | 18708158 | [
{
"id": "DS.d808.s0",
"type": "",
"text": [
"Roscovitine reduced amounts of the caspase inhibitor XIAP, and API-2 increased amounts of the BH3-only protein Bim."
],
"offsets": [
[
0,
115
]
]
},
{
"id": "DS.d808.s1",
"type": "",
"text": [
"Bax accumulated in mitochondria in response to API-2, whereas release of cytochrome c from mitochondria required both API-2 and roscovitine."
],
"offsets": [
[
116,
256
]
]
},
{
"id": "DS.d808.s2",
"type": "",
"text": [
"We suggest that roscovitine elicits events that activate Bax once it translocates to mitochondria and that inactivation of cdk9 signals these events and the down-regulation of XIAP."
],
"offsets": [
[
257,
438
]
]
}
] | [
{
"id": "DS.d808.s0.e0",
"type": "compound",
"text": [
"Roscovitine"
],
"offsets": [
[
0,
11
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "160355"
}
]
},
{
"id": "DS.d808.s0.e1",
"type": "protein",
"text": [
"Bim"
],
"offsets": [
[
111,
114
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O54918"
},
{
"db_name": "UniProt",
"db_id": "O88498"
}
]
},
{
"id": "DS.d808.s1.e0",
"type": "protein",
"text": [
"Bax"
],
"offsets": [
[
116,
119
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P27297"
},
{
"db_name": "UniProt",
"db_id": "Q07813"
},
{
"db_name": "UniProt",
"db_id": "Q63690"
}
]
},
{
"id": "DS.d808.s1.e1",
"type": "protein",
"text": [
"cytochrome c"
],
"offsets": [
[
189,
201
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O07091"
},
{
"db_name": "UniProt",
"db_id": "O13393"
},
{
"db_name": "UniProt",
"db_id": "O22642"
},
{
"db_name": "UniProt",
"db_id": "O93863"
},
{
"db_name": "UniProt",
"db_id": "P00002"
},
{
"db_name": "UniProt",
"db_id": "P00003"
},
{
"db_name": "UniProt",
"db_id": "P00004"
},
{
"db_name": "UniProt",
"db_id": "P00007"
},
{
"db_name": "UniProt",
"db_id": "P00008"
},
{
"db_name": "UniProt",
"db_id": "P00011"
},
{
"db_name": "UniProt",
"db_id": "P00012"
},
{
"db_name": "UniProt",
"db_id": "P00013"
},
{
"db_name": "UniProt",
"db_id": "P00014"
},
{
"db_name": "UniProt",
"db_id": "P00017"
},
{
"db_name": "UniProt",
"db_id": "P00018"
},
{
"db_name": "UniProt",
"db_id": "P00019"
},
{
"db_name": "UniProt",
"db_id": "P00020"
},
{
"db_name": "UniProt",
"db_id": "P00021"
},
{
"db_name": "UniProt",
"db_id": "P00022"
},
{
"db_name": "UniProt",
"db_id": "P00024"
},
{
"db_name": "UniProt",
"db_id": "P00025"
},
{
"db_name": "UniProt",
"db_id": "P00027"
},
{
"db_name": "UniProt",
"db_id": "P00028"
},
{
"db_name": "UniProt",
"db_id": "P00029"
},
{
"db_name": "UniProt",
"db_id": "P00030"
},
{
"db_name": "UniProt",
"db_id": "P00031"
},
{
"db_name": "UniProt",
"db_id": "P00032"
},
{
"db_name": "UniProt",
"db_id": "P00035"
},
{
"db_name": "UniProt",
"db_id": "P00036"
},
{
"db_name": "UniProt",
"db_id": "P00037"
},
{
"db_name": "UniProt",
"db_id": "P00038"
},
{
"db_name": "UniProt",
"db_id": "P00039"
},
{
"db_name": "UniProt",
"db_id": "P00040"
},
{
"db_name": "UniProt",
"db_id": "P00041"
},
{
"db_name": "UniProt",
"db_id": "P00042"
},
{
"db_name": "UniProt",
"db_id": "P00043"
},
{
"db_name": "UniProt",
"db_id": "P00046"
},
{
"db_name": "UniProt",
"db_id": "P00047"
},
{
"db_name": "UniProt",
"db_id": "P00048"
},
{
"db_name": "UniProt",
"db_id": "P00049"
},
{
"db_name": "UniProt",
"db_id": "P00051"
},
{
"db_name": "UniProt",
"db_id": "P00052"
},
{
"db_name": "UniProt",
"db_id": "P00053"
},
{
"db_name": "UniProt",
"db_id": "P00054"
},
{
"db_name": "UniProt",
"db_id": "P00055"
},
{
"db_name": "UniProt",
"db_id": "P00056"
},
{
"db_name": "UniProt",
"db_id": "P00057"
},
{
"db_name": "UniProt",
"db_id": "P00058"
},
{
"db_name": "UniProt",
"db_id": "P00059"
},
{
"db_name": "UniProt",
"db_id": "P00060"
},
{
"db_name": "UniProt",
"db_id": "P00061"
},
{
"db_name": "UniProt",
"db_id": "P00062"
},
{
"db_name": "UniProt",
"db_id": "P00063"
},
{
"db_name": "UniProt",
"db_id": "P00064"
},
{
"db_name": "UniProt",
"db_id": "P00065"
},
{
"db_name": "UniProt",
"db_id": "P00066"
},
{
"db_name": "UniProt",
"db_id": "P00067"
},
{
"db_name": "UniProt",
"db_id": "P00068"
},
{
"db_name": "UniProt",
"db_id": "P00069"
},
{
"db_name": "UniProt",
"db_id": "P00070"
},
{
"db_name": "UniProt",
"db_id": "P00071"
},
{
"db_name": "UniProt",
"db_id": "P00072"
},
{
"db_name": "UniProt",
"db_id": "P00073"
},
{
"db_name": "UniProt",
"db_id": "P00074"
},
{
"db_name": "UniProt",
"db_id": "P00075"
},
{
"db_name": "UniProt",
"db_id": "P00076"
},
{
"db_name": "UniProt",
"db_id": "P00077"
},
{
"db_name": "UniProt",
"db_id": "P00078"
},
{
"db_name": "UniProt",
"db_id": "P00079"
},
{
"db_name": "UniProt",
"db_id": "P12831"
},
{
"db_name": "UniProt",
"db_id": "P15451"
},
{
"db_name": "UniProt",
"db_id": "P18822"
},
{
"db_name": "UniProt",
"db_id": "P19681"
},
{
"db_name": "UniProt",
"db_id": "P19974"
},
{
"db_name": "UniProt",
"db_id": "P21665"
},
{
"db_name": "UniProt",
"db_id": "P22342"
},
{
"db_name": "UniProt",
"db_id": "P25400"
},
{
"db_name": "UniProt",
"db_id": "P29380"
},
{
"db_name": "UniProt",
"db_id": "P32556"
},
{
"db_name": "UniProt",
"db_id": "P38091"
},
{
"db_name": "UniProt",
"db_id": "P53698"
},
{
"db_name": "UniProt",
"db_id": "P56205"
},
{
"db_name": "UniProt",
"db_id": "P59218"
},
{
"db_name": "UniProt",
"db_id": "P62772"
},
{
"db_name": "UniProt",
"db_id": "P62773"
},
{
"db_name": "UniProt",
"db_id": "P62894"
},
{
"db_name": "UniProt",
"db_id": "P62895"
},
{
"db_name": "UniProt",
"db_id": "P62896"
},
{
"db_name": "UniProt",
"db_id": "P67881"
},
{
"db_name": "UniProt",
"db_id": "P67882"
},
{
"db_name": "UniProt",
"db_id": "P68096"
},
{
"db_name": "UniProt",
"db_id": "P68097"
},
{
"db_name": "UniProt",
"db_id": "P68098"
},
{
"db_name": "UniProt",
"db_id": "P68099"
},
{
"db_name": "UniProt",
"db_id": "P68100"
},
{
"db_name": "UniProt",
"db_id": "P68517"
},
{
"db_name": "UniProt",
"db_id": "P68518"
},
{
"db_name": "UniProt",
"db_id": "P68519"
},
{
"db_name": "UniProt",
"db_id": "P81280"
},
{
"db_name": "UniProt",
"db_id": "P81459"
},
{
"db_name": "UniProt",
"db_id": "P99998"
},
{
"db_name": "UniProt",
"db_id": "P99999"
},
{
"db_name": "UniProt",
"db_id": "Q41346"
},
{
"db_name": "UniProt",
"db_id": "Q4HVX7"
},
{
"db_name": "UniProt",
"db_id": "Q52V08"
},
{
"db_name": "UniProt",
"db_id": "Q52V09"
},
{
"db_name": "UniProt",
"db_id": "Q52V10"
},
{
"db_name": "UniProt",
"db_id": "Q5RFH4"
},
{
"db_name": "UniProt",
"db_id": "Q640U4"
},
{
"db_name": "UniProt",
"db_id": "Q6C9Q0"
},
{
"db_name": "UniProt",
"db_id": "Q6IQM2"
},
{
"db_name": "UniProt",
"db_id": "Q6Q4H8"
},
{
"db_name": "UniProt",
"db_id": "Q6QLW4"
},
{
"db_name": "UniProt",
"db_id": "Q6WUX8"
},
{
"db_name": "UniProt",
"db_id": "Q753F4"
},
{
"db_name": "UniProt",
"db_id": "Q7YR71"
},
{
"db_name": "UniProt",
"db_id": "Q96VP3"
}
]
},
{
"id": "DS.d808.s1.e2",
"type": "compound",
"text": [
"roscovitine"
],
"offsets": [
[
244,
255
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "160355"
}
]
},
{
"id": "DS.d808.s2.e0",
"type": "compound",
"text": [
"roscovitine"
],
"offsets": [
[
273,
284
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "160355"
}
]
},
{
"id": "DS.d808.s2.e1",
"type": "protein",
"text": [
"Bax"
],
"offsets": [
[
314,
317
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P27297"
},
{
"db_name": "UniProt",
"db_id": "Q07813"
},
{
"db_name": "UniProt",
"db_id": "Q63690"
}
]
},
{
"id": "DS.d808.s2.e2",
"type": "protein",
"text": [
"cdk9"
],
"offsets": [
[
380,
384
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q641Z4"
},
{
"db_name": "UniProt",
"db_id": "Q6GLD8"
},
{
"db_name": "UniProt",
"db_id": "Q96WV9"
},
{
"db_name": "UniProt",
"db_id": "Q99J95"
}
]
}
] | [] | [] | [
{
"id": "DS.d808.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d808.s1.e2",
"arg2_id": "DS.d808.s1.e1",
"normalized": []
},
{
"id": "DS.d808.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d808.s2.e0",
"arg2_id": "DS.d808.s2.e2",
"normalized": []
},
{
"id": "DS.d808.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d808.s2.e0",
"arg2_id": "DS.d808.s2.e1",
"normalized": []
}
] |
DS.d809 | 18708191 | [
{
"id": "DS.d809.s0",
"type": "",
"text": [
"Intravenous glutamine enhances COX-2 activity giving cardioprotection."
],
"offsets": [
[
0,
70
]
]
},
{
"id": "DS.d809.s1",
"type": "",
"text": [
"We investigated whether acute intravenous glutamine, through an effect on cyclooxygenase (COX)-2 and heat shock protein (HSP) 72, might induce preconditioning."
],
"offsets": [
[
71,
230
]
]
}
] | [
{
"id": "DS.d809.s0.e0",
"type": "compound",
"text": [
"glutamine"
],
"offsets": [
[
12,
21
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "738"
},
{
"db_name": "PubChem",
"db_id": "5961"
}
]
},
{
"id": "DS.d809.s0.e1",
"type": "protein",
"text": [
"COX-2"
],
"offsets": [
[
31,
36
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O02768"
},
{
"db_name": "UniProt",
"db_id": "O19183"
},
{
"db_name": "UniProt",
"db_id": "O62698"
},
{
"db_name": "UniProt",
"db_id": "O62725"
},
{
"db_name": "UniProt",
"db_id": "P27607"
},
{
"db_name": "UniProt",
"db_id": "P35354"
},
{
"db_name": "UniProt",
"db_id": "P35355"
},
{
"db_name": "UniProt",
"db_id": "P70682"
},
{
"db_name": "UniProt",
"db_id": "P79208"
},
{
"db_name": "UniProt",
"db_id": "Q05769"
}
]
},
{
"id": "DS.d809.s1.e0",
"type": "compound",
"text": [
"glutamine"
],
"offsets": [
[
113,
122
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "738"
},
{
"db_name": "PubChem",
"db_id": "5961"
}
]
},
{
"id": "DS.d809.s1.e1",
"type": "protein",
"text": [
"COX"
],
"offsets": [
[
161,
164
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P11353"
},
{
"db_name": "UniProt",
"db_id": "P36551"
},
{
"db_name": "UniProt",
"db_id": "P36552"
},
{
"db_name": "UniProt",
"db_id": "Q9UTE2"
},
{
"db_name": "UniProt",
"db_id": "Q9V3D2"
}
]
},
{
"id": "DS.d809.s1.e2",
"type": "protein",
"text": [
"HSP"
],
"offsets": [
[
192,
195
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P32590"
}
]
}
] | [] | [] | [
{
"id": "DS.d809.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d809.s0.e0",
"arg2_id": "DS.d809.s0.e1",
"normalized": []
},
{
"id": "DS.d809.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d809.s1.e0",
"arg2_id": "DS.d809.s1.e2",
"normalized": []
},
{
"id": "DS.d809.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d809.s1.e0",
"arg2_id": "DS.d809.s1.e1",
"normalized": []
}
] |
DS.d810 | 18708284 | [
{
"id": "DS.d810.s0",
"type": "",
"text": [
"Islets from taurine-supplemented mice had: (i) significantly higher insulin content, (ii) increased insulin secretion at stimulatory glucose concentrations, (iii) significantly displaced the dose-response curve for glucose-induced insulin release to the left, (iv) increased glucose metabolism at 5.6 and 11.1-mmol/L concentrations; (v) slowed cytosolic Ca2+ concentration ((Ca2+)i) oscillations in response to stimulatory glucose concentrations; (vi) increased insulin, sulfonylurea receptor-1, glucokinase, Glut-2, proconvertase and pancreas duodenum homeobox-1 (PDX-1) gene expression and (vii) increased PDX-1 expression in the nucleus."
],
"offsets": [
[
0,
640
]
]
},
{
"id": "DS.d810.s1",
"type": "",
"text": [
"Moreover, taurine supplementation significantly increased both basal and insulin stimulated tyrosine phosphorylation of the insulin receptor in skeletal muscle and liver tissues."
],
"offsets": [
[
641,
819
]
]
},
{
"id": "DS.d810.s2",
"type": "",
"text": [
"These results indicate that taurine controls glucose homeostasis by regulating the expression of genes required for glucose-stimulated insulin secretion."
],
"offsets": [
[
820,
973
]
]
},
{
"id": "DS.d810.s3",
"type": "",
"text": [
"In addition, taurine enhances peripheral insulin sensitivity."
],
"offsets": [
[
974,
1035
]
]
}
] | [
{
"id": "DS.d810.s0.e0",
"type": "compound",
"text": [
"taurine"
],
"offsets": [
[
12,
19
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1123"
}
]
},
{
"id": "DS.d810.s0.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
68,
75
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d810.s0.e2",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
100,
107
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d810.s0.e3",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
100,
107
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d810.s0.e4",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
100,
107
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d810.s0.e5",
"type": "protein",
"text": [
"sulfonylurea receptor-1"
],
"offsets": [
[
471,
494
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q09427"
},
{
"db_name": "UniProt",
"db_id": "Q09428"
},
{
"db_name": "UniProt",
"db_id": "Q09429"
}
]
},
{
"id": "DS.d810.s0.e6",
"type": "protein",
"text": [
"glucokinase"
],
"offsets": [
[
496,
507
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O25731"
},
{
"db_name": "UniProt",
"db_id": "P0A4E1"
},
{
"db_name": "UniProt",
"db_id": "P0A4E2"
},
{
"db_name": "UniProt",
"db_id": "P0A6V8"
},
{
"db_name": "UniProt",
"db_id": "P0A6V9"
},
{
"db_name": "UniProt",
"db_id": "P17712"
},
{
"db_name": "UniProt",
"db_id": "P21908"
},
{
"db_name": "UniProt",
"db_id": "P35557"
},
{
"db_name": "UniProt",
"db_id": "P52792"
},
{
"db_name": "UniProt",
"db_id": "P54495"
},
{
"db_name": "UniProt",
"db_id": "P58616"
},
{
"db_name": "UniProt",
"db_id": "P58617"
},
{
"db_name": "UniProt",
"db_id": "P58618"
},
{
"db_name": "UniProt",
"db_id": "P58619"
},
{
"db_name": "UniProt",
"db_id": "P64253"
},
{
"db_name": "UniProt",
"db_id": "P64254"
},
{
"db_name": "UniProt",
"db_id": "P82680"
},
{
"db_name": "UniProt",
"db_id": "Q55855"
},
{
"db_name": "UniProt",
"db_id": "Q56198"
},
{
"db_name": "UniProt",
"db_id": "Q59171"
},
{
"db_name": "UniProt",
"db_id": "Q668N7"
},
{
"db_name": "UniProt",
"db_id": "Q6D7C4"
},
{
"db_name": "UniProt",
"db_id": "Q7N6Y0"
},
{
"db_name": "UniProt",
"db_id": "Q83K86"
},
{
"db_name": "UniProt",
"db_id": "Q87EG6"
},
{
"db_name": "UniProt",
"db_id": "Q8FFD4"
},
{
"db_name": "UniProt",
"db_id": "Q8FV09"
},
{
"db_name": "UniProt",
"db_id": "Q8P8U7"
},
{
"db_name": "UniProt",
"db_id": "Q8PKU2"
},
{
"db_name": "UniProt",
"db_id": "Q8UIV7"
},
{
"db_name": "UniProt",
"db_id": "Q8YDC6"
},
{
"db_name": "UniProt",
"db_id": "Q92407"
},
{
"db_name": "UniProt",
"db_id": "Q92T27"
},
{
"db_name": "UniProt",
"db_id": "Q93IM5"
},
{
"db_name": "UniProt",
"db_id": "Q98DM2"
},
{
"db_name": "UniProt",
"db_id": "Q9A6N3"
},
{
"db_name": "UniProt",
"db_id": "Q9HZ46"
},
{
"db_name": "UniProt",
"db_id": "Q9KCZ4"
},
{
"db_name": "UniProt",
"db_id": "Q9PEG4"
},
{
"db_name": "UniProt",
"db_id": "Q9ZKB0"
}
]
},
{
"id": "DS.d810.s0.e7",
"type": "protein",
"text": [
"Glut-2"
],
"offsets": [
[
509,
515
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P12336"
},
{
"db_name": "UniProt",
"db_id": "P14246"
}
]
},
{
"id": "DS.d810.s0.e8",
"type": "protein",
"text": [
"pancreas duodenum homeobox-1"
],
"offsets": [
[
535,
563
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P52945"
},
{
"db_name": "UniProt",
"db_id": "P52946"
}
]
},
{
"id": "DS.d810.s0.e9",
"type": "protein",
"text": [
"PDX-1"
],
"offsets": [
[
565,
570
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P52945"
}
]
},
{
"id": "DS.d810.s0.e10",
"type": "protein",
"text": [
"PDX-1"
],
"offsets": [
[
608,
613
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P52945"
}
]
},
{
"id": "DS.d810.s1.e0",
"type": "compound",
"text": [
"taurine"
],
"offsets": [
[
651,
658
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1123"
}
]
},
{
"id": "DS.d810.s1.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
714,
721
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d810.s1.e2",
"type": "compound",
"text": [
"tyrosine"
],
"offsets": [
[
733,
741
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1153"
},
{
"db_name": "PubChem",
"db_id": "6057"
},
{
"db_name": "PubChem",
"db_id": "5460803"
}
]
},
{
"id": "DS.d810.s1.e3",
"type": "protein",
"text": [
"insulin receptor"
],
"offsets": [
[
765,
781
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q28516"
}
]
},
{
"id": "DS.d810.s2.e0",
"type": "compound",
"text": [
"taurine"
],
"offsets": [
[
848,
855
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1123"
}
]
},
{
"id": "DS.d810.s2.e1",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
865,
872
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d810.s2.e2",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
955,
962
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d810.s3.e0",
"type": "compound",
"text": [
"taurine"
],
"offsets": [
[
987,
994
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1123"
}
]
},
{
"id": "DS.d810.s3.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
1015,
1022
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
}
] | [] | [] | [
{
"id": "DS.d810.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s0.e0",
"arg2_id": "DS.d810.s0.e1",
"normalized": []
},
{
"id": "DS.d810.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s0.e0",
"arg2_id": "DS.d810.s0.e7",
"normalized": []
},
{
"id": "DS.d810.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s0.e0",
"arg2_id": "DS.d810.s0.e8",
"normalized": []
},
{
"id": "DS.d810.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s0.e0",
"arg2_id": "DS.d810.s0.e6",
"normalized": []
},
{
"id": "DS.d810.s0.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s0.e0",
"arg2_id": "DS.d810.s0.e9",
"normalized": []
},
{
"id": "DS.d810.s0.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s0.e0",
"arg2_id": "DS.d810.s0.e5",
"normalized": []
},
{
"id": "DS.d810.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s1.e0",
"arg2_id": "DS.d810.s1.e3",
"normalized": []
},
{
"id": "DS.d810.s1.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s1.e2",
"arg2_id": "DS.d810.s1.e3",
"normalized": []
},
{
"id": "DS.d810.s1.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s1.e2",
"arg2_id": "DS.d810.s1.e1",
"normalized": []
},
{
"id": "DS.d810.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s2.e0",
"arg2_id": "DS.d810.s2.e2",
"normalized": []
},
{
"id": "DS.d810.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s2.e1",
"arg2_id": "DS.d810.s2.e2",
"normalized": []
},
{
"id": "DS.d810.s3.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d810.s3.e0",
"arg2_id": "DS.d810.s3.e1",
"normalized": []
}
] |
DS.d811 | 18708285 | [
{
"id": "DS.d811.s0",
"type": "",
"text": [
"Furthermore, treatment of lycopene and EPA also synergistically blocked the activation of downstream mTOR molecule."
],
"offsets": [
[
0,
115
]
]
},
{
"id": "DS.d811.s1",
"type": "",
"text": [
"Immunocytochemical staining results revealed that lycopene and EPA could also up-regulate the expression of apoptotic proteins such as Bax and Fas ligand to suppress cell survival."
],
"offsets": [
[
116,
296
]
]
}
] | [
{
"id": "DS.d811.s0.e0",
"type": "compound",
"text": [
"lycopene"
],
"offsets": [
[
26,
34
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "446925"
}
]
},
{
"id": "DS.d811.s0.e1",
"type": "protein",
"text": [
"mTOR"
],
"offsets": [
[
101,
105
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P42345"
},
{
"db_name": "UniProt",
"db_id": "P42346"
},
{
"db_name": "UniProt",
"db_id": "Q9JLN9"
}
]
},
{
"id": "DS.d811.s1.e0",
"type": "compound",
"text": [
"lycopene"
],
"offsets": [
[
166,
174
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "446925"
}
]
},
{
"id": "DS.d811.s1.e1",
"type": "protein",
"text": [
"Bax"
],
"offsets": [
[
251,
254
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P27297"
},
{
"db_name": "UniProt",
"db_id": "Q07813"
},
{
"db_name": "UniProt",
"db_id": "Q63690"
}
]
},
{
"id": "DS.d811.s1.e2",
"type": "protein",
"text": [
"Fas ligand"
],
"offsets": [
[
259,
269
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P36940"
},
{
"db_name": "UniProt",
"db_id": "P41047"
},
{
"db_name": "UniProt",
"db_id": "P48023"
},
{
"db_name": "UniProt",
"db_id": "P63306"
},
{
"db_name": "UniProt",
"db_id": "P63307"
},
{
"db_name": "UniProt",
"db_id": "P63308"
},
{
"db_name": "UniProt",
"db_id": "Q861W5"
},
{
"db_name": "UniProt",
"db_id": "Q9BDN1"
},
{
"db_name": "UniProt",
"db_id": "Q9BEA8"
}
]
}
] | [] | [] | [
{
"id": "DS.d811.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d811.s0.e0",
"arg2_id": "DS.d811.s0.e1",
"normalized": []
},
{
"id": "DS.d811.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d811.s1.e0",
"arg2_id": "DS.d811.s1.e1",
"normalized": []
},
{
"id": "DS.d811.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d811.s1.e0",
"arg2_id": "DS.d811.s1.e2",
"normalized": []
}
] |
DS.d812 | 18709446 | [
{
"id": "DS.d812.s0",
"type": "",
"text": [
"Amino acids (alanine, aspartic acid, glutamic acid) and glucose oxidase (GOx) were adsorbed on CNF and the results were compared with those obtained when activated carbon (AC) was used as support."
],
"offsets": [
[
0,
196
]
]
}
] | [
{
"id": "DS.d812.s0.e0",
"type": "compound",
"text": [
"alanine"
],
"offsets": [
[
13,
20
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "602"
},
{
"db_name": "PubChem",
"db_id": "4580"
},
{
"db_name": "PubChem",
"db_id": "5950"
},
{
"db_name": "PubChem",
"db_id": "71080"
}
]
},
{
"id": "DS.d812.s0.e1",
"type": "compound",
"text": [
"aspartic acid"
],
"offsets": [
[
22,
35
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "424"
},
{
"db_name": "PubChem",
"db_id": "5960"
},
{
"db_name": "PubChem",
"db_id": "83887"
}
]
},
{
"id": "DS.d812.s0.e2",
"type": "protein",
"text": [
"glucose oxidase"
],
"offsets": [
[
56,
71
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P81156"
}
]
},
{
"id": "DS.d812.s0.e3",
"type": "compound",
"text": [
"activated carbon"
],
"offsets": [
[
154,
170
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "297"
}
]
}
] | [] | [] | [] |
DS.d814 | 18709646 | [
{
"id": "DS.d814.s0",
"type": "",
"text": [
"The NSCs and neuroblasts had epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor alpha (PDGFRalpha) expressed on the ciliary apparatus and were the only cell types incorporating the proliferation marker BrdU."
],
"offsets": [
[
0,
240
]
]
},
{
"id": "DS.d814.s1",
"type": "",
"text": [
"Ependymal and displaced ependymal cells also expressed EGFR and PDGFRalpha on their cilia but did not incorporate BrdU."
],
"offsets": [
[
241,
360
]
]
}
] | [
{
"id": "DS.d814.s0.e0",
"type": "protein",
"text": [
"epidermal growth factor receptor"
],
"offsets": [
[
29,
61
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P55245"
}
]
},
{
"id": "DS.d814.s0.e1",
"type": "protein",
"text": [
"EGFR"
],
"offsets": [
[
63,
67
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P00533"
},
{
"db_name": "UniProt",
"db_id": "P13387"
},
{
"db_name": "UniProt",
"db_id": "P55245"
}
]
},
{
"id": "DS.d814.s0.e2",
"type": "protein",
"text": [
"PDGFRalpha"
],
"offsets": [
[
120,
130
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P16234"
},
{
"db_name": "UniProt",
"db_id": "P20786"
},
{
"db_name": "UniProt",
"db_id": "P26618"
},
{
"db_name": "UniProt",
"db_id": "P26619"
},
{
"db_name": "UniProt",
"db_id": "Q8AXC7"
},
{
"db_name": "UniProt",
"db_id": "Q9DE49"
},
{
"db_name": "UniProt",
"db_id": "Q9PUF6"
}
]
},
{
"id": "DS.d814.s0.e3",
"type": "compound",
"text": [
"BrdU"
],
"offsets": [
[
235,
239
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6035"
}
]
},
{
"id": "DS.d814.s1.e0",
"type": "protein",
"text": [
"EGFR"
],
"offsets": [
[
296,
300
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P00533"
},
{
"db_name": "UniProt",
"db_id": "P13387"
},
{
"db_name": "UniProt",
"db_id": "P55245"
}
]
},
{
"id": "DS.d814.s1.e1",
"type": "protein",
"text": [
"PDGFRalpha"
],
"offsets": [
[
305,
315
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P16234"
},
{
"db_name": "UniProt",
"db_id": "P20786"
},
{
"db_name": "UniProt",
"db_id": "P26618"
},
{
"db_name": "UniProt",
"db_id": "P26619"
},
{
"db_name": "UniProt",
"db_id": "Q8AXC7"
},
{
"db_name": "UniProt",
"db_id": "Q9DE49"
},
{
"db_name": "UniProt",
"db_id": "Q9PUF6"
}
]
},
{
"id": "DS.d814.s1.e2",
"type": "compound",
"text": [
"BrdU"
],
"offsets": [
[
355,
359
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6035"
}
]
}
] | [] | [] | [] |
DS.d815 | 18709647 | [
{
"id": "DS.d815.s0",
"type": "",
"text": [
"Both 17alpha- and 17beta-estradiol elicited rapid phosphorylation of p42/44MAPK, Akt, and GSK-3beta within 8 min."
],
"offsets": [
[
0,
113
]
]
}
] | [
{
"id": "DS.d815.s0.e0",
"type": "compound",
"text": [
"17beta-estradiol"
],
"offsets": [
[
18,
34
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5757"
}
]
},
{
"id": "DS.d815.s0.e1",
"type": "protein",
"text": [
"p42"
],
"offsets": [
[
69,
72
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P46672"
},
{
"db_name": "UniProt",
"db_id": "Q27272"
},
{
"db_name": "UniProt",
"db_id": "Q8NFH3"
},
{
"db_name": "UniProt",
"db_id": "Q9SB81"
}
]
},
{
"id": "DS.d815.s0.e2",
"type": "protein",
"text": [
"Akt"
],
"offsets": [
[
81,
84
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P31750"
},
{
"db_name": "UniProt",
"db_id": "Q8INB9"
}
]
},
{
"id": "DS.d815.s0.e3",
"type": "protein",
"text": [
"GSK-3beta"
],
"offsets": [
[
90,
99
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P18266"
},
{
"db_name": "UniProt",
"db_id": "P49841"
},
{
"db_name": "UniProt",
"db_id": "Q5YJC2"
},
{
"db_name": "UniProt",
"db_id": "Q9WV60"
}
]
}
] | [] | [] | [
{
"id": "DS.d815.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d815.s0.e0",
"arg2_id": "DS.d815.s0.e2",
"normalized": []
},
{
"id": "DS.d815.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d815.s0.e0",
"arg2_id": "DS.d815.s0.e3",
"normalized": []
},
{
"id": "DS.d815.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d815.s0.e0",
"arg2_id": "DS.d815.s0.e1",
"normalized": []
}
] |
DS.d816 | 18709649 | [
{
"id": "DS.d816.s0",
"type": "",
"text": [
"Whereas Zn2+-dependent upregulation of metallothionein may help to counteract excessive astrocyte swelling and production of reactive oxygen and nitrogen oxide species, stimulation of PBR expression may augment HE development."
],
"offsets": [
[
0,
226
]
]
}
] | [
{
"id": "DS.d816.s0.e0",
"type": "compound",
"text": [
"Zn2"
],
"offsets": [
[
8,
11
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "32051"
}
]
},
{
"id": "DS.d816.s0.e1",
"type": "protein",
"text": [
"metallothionein"
],
"offsets": [
[
39,
54
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O02033"
},
{
"db_name": "UniProt",
"db_id": "O13257"
},
{
"db_name": "UniProt",
"db_id": "O18842"
},
{
"db_name": "UniProt",
"db_id": "O42152"
},
{
"db_name": "UniProt",
"db_id": "O93571"
},
{
"db_name": "UniProt",
"db_id": "P02807"
},
{
"db_name": "UniProt",
"db_id": "P04358"
},
{
"db_name": "UniProt",
"db_id": "P07216"
},
{
"db_name": "UniProt",
"db_id": "P08002"
},
{
"db_name": "UniProt",
"db_id": "P23038"
},
{
"db_name": "UniProt",
"db_id": "P25127"
},
{
"db_name": "UniProt",
"db_id": "P25128"
},
{
"db_name": "UniProt",
"db_id": "P30331"
},
{
"db_name": "UniProt",
"db_id": "P30565"
},
{
"db_name": "UniProt",
"db_id": "P51902"
},
{
"db_name": "UniProt",
"db_id": "P52723"
},
{
"db_name": "UniProt",
"db_id": "P52725"
},
{
"db_name": "UniProt",
"db_id": "P52726"
},
{
"db_name": "UniProt",
"db_id": "P52728"
},
{
"db_name": "UniProt",
"db_id": "P55945"
},
{
"db_name": "UniProt",
"db_id": "P55946"
},
{
"db_name": "UniProt",
"db_id": "P55948"
},
{
"db_name": "UniProt",
"db_id": "P55951"
},
{
"db_name": "UniProt",
"db_id": "P55952"
},
{
"db_name": "UniProt",
"db_id": "P55953"
},
{
"db_name": "UniProt",
"db_id": "P68494"
},
{
"db_name": "UniProt",
"db_id": "P68495"
},
{
"db_name": "UniProt",
"db_id": "P68497"
},
{
"db_name": "UniProt",
"db_id": "P68498"
},
{
"db_name": "UniProt",
"db_id": "P68499"
},
{
"db_name": "UniProt",
"db_id": "P80367"
},
{
"db_name": "UniProt",
"db_id": "P80593"
},
{
"db_name": "UniProt",
"db_id": "P84865"
},
{
"db_name": "UniProt",
"db_id": "Q05890"
},
{
"db_name": "UniProt",
"db_id": "Q6J1T3"
},
{
"db_name": "UniProt",
"db_id": "Q6S4N8"
},
{
"db_name": "UniProt",
"db_id": "Q6XUW5"
},
{
"db_name": "UniProt",
"db_id": "Q708T3"
},
{
"db_name": "UniProt",
"db_id": "Q7ZZP9"
},
{
"db_name": "UniProt",
"db_id": "Q800D3"
},
{
"db_name": "UniProt",
"db_id": "Q8UVY1"
},
{
"db_name": "UniProt",
"db_id": "Q94550"
},
{
"db_name": "UniProt",
"db_id": "Q9IB50"
},
{
"db_name": "UniProt",
"db_id": "Q9U568"
}
]
},
{
"id": "DS.d816.s0.e2",
"type": "compound",
"text": [
"oxygen"
],
"offsets": [
[
134,
140
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "977"
}
]
},
{
"id": "DS.d816.s0.e3",
"type": "compound",
"text": [
"nitrogen oxide"
],
"offsets": [
[
145,
159
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "945"
},
{
"db_name": "PubChem",
"db_id": "948"
},
{
"db_name": "PubChem",
"db_id": "25352"
},
{
"db_name": "PubChem",
"db_id": "61526"
},
{
"db_name": "PubChem",
"db_id": "160954"
},
{
"db_name": "PubChem",
"db_id": "3609161"
}
]
},
{
"id": "DS.d816.s0.e4",
"type": "protein",
"text": [
"PBR"
],
"offsets": [
[
184,
187
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P16257"
},
{
"db_name": "UniProt",
"db_id": "P30535"
},
{
"db_name": "UniProt",
"db_id": "P30536"
},
{
"db_name": "UniProt",
"db_id": "P50637"
}
]
}
] | [] | [] | [
{
"id": "DS.d816.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d816.s0.e3",
"arg2_id": "DS.d816.s0.e1",
"normalized": []
},
{
"id": "DS.d816.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d816.s0.e2",
"arg2_id": "DS.d816.s0.e1",
"normalized": []
},
{
"id": "DS.d816.s0.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d816.s0.e0",
"arg2_id": "DS.d816.s0.e1",
"normalized": []
}
] |
DS.d817 | 18709661 | [
{
"id": "DS.d817.s0",
"type": "",
"text": [
"Accordingly, the TLR3 agonist poly(I:C) (PIC) induced higher release of IFN-beta in primary and purified astroglia than in microglia."
],
"offsets": [
[
0,
133
]
]
},
{
"id": "DS.d817.s1",
"type": "",
"text": [
"As siRNA, PIC induced IP-10, Stat1, VCAM-1, and Cox-2 and increased TLR3 mRNA expression."
],
"offsets": [
[
134,
223
]
]
}
] | [
{
"id": "DS.d817.s0.e0",
"type": "compound",
"text": [
"poly(I:C"
],
"offsets": [
[
30,
38
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "32744"
},
{
"db_name": "PubChem",
"db_id": "213546"
},
{
"db_name": "PubChem",
"db_id": "274740"
}
]
},
{
"id": "DS.d817.s0.e1",
"type": "compound",
"text": [
"PIC"
],
"offsets": [
[
41,
44
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1854"
}
]
},
{
"id": "DS.d817.s0.e2",
"type": "protein",
"text": [
"IFN-beta"
],
"offsets": [
[
72,
80
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O77812"
},
{
"db_name": "UniProt",
"db_id": "P01574"
},
{
"db_name": "UniProt",
"db_id": "P01575"
},
{
"db_name": "UniProt",
"db_id": "P05012"
},
{
"db_name": "UniProt",
"db_id": "P70499"
},
{
"db_name": "UniProt",
"db_id": "Q6XZW6"
},
{
"db_name": "UniProt",
"db_id": "Q9N2J0"
}
]
},
{
"id": "DS.d817.s1.e0",
"type": "compound",
"text": [
"PIC"
],
"offsets": [
[
144,
147
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1854"
}
]
},
{
"id": "DS.d817.s1.e1",
"type": "protein",
"text": [
"IP-10"
],
"offsets": [
[
156,
161
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P02778"
},
{
"db_name": "UniProt",
"db_id": "P17515"
},
{
"db_name": "UniProt",
"db_id": "P48973"
}
]
},
{
"id": "DS.d817.s1.e2",
"type": "protein",
"text": [
"Stat1"
],
"offsets": [
[
163,
168
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P42225"
}
]
},
{
"id": "DS.d817.s1.e3",
"type": "protein",
"text": [
"VCAM-1"
],
"offsets": [
[
170,
176
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P19320"
},
{
"db_name": "UniProt",
"db_id": "P29533"
},
{
"db_name": "UniProt",
"db_id": "P29534"
},
{
"db_name": "UniProt",
"db_id": "Q28260"
}
]
},
{
"id": "DS.d817.s1.e4",
"type": "protein",
"text": [
"Cox-2"
],
"offsets": [
[
182,
187
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P00411"
},
{
"db_name": "UniProt",
"db_id": "P24894"
},
{
"db_name": "UniProt",
"db_id": "P35355"
},
{
"db_name": "UniProt",
"db_id": "Q05769"
},
{
"db_name": "UniProt",
"db_id": "Q8HEC3"
},
{
"db_name": "UniProt",
"db_id": "Q8SEM9"
}
]
},
{
"id": "DS.d817.s1.e5",
"type": "protein",
"text": [
"TLR3"
],
"offsets": [
[
202,
206
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O15455"
},
{
"db_name": "UniProt",
"db_id": "Q0PV50"
},
{
"db_name": "UniProt",
"db_id": "Q5TJ59"
}
]
}
] | [] | [] | [
{
"id": "DS.d817.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d817.s0.e0",
"arg2_id": "DS.d817.s0.e2",
"normalized": []
},
{
"id": "DS.d817.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d817.s0.e1",
"arg2_id": "DS.d817.s0.e2",
"normalized": []
},
{
"id": "DS.d817.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d817.s1.e0",
"arg2_id": "DS.d817.s1.e1",
"normalized": []
},
{
"id": "DS.d817.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d817.s1.e0",
"arg2_id": "DS.d817.s1.e3",
"normalized": []
},
{
"id": "DS.d817.s1.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d817.s1.e0",
"arg2_id": "DS.d817.s1.e2",
"normalized": []
},
{
"id": "DS.d817.s1.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d817.s1.e0",
"arg2_id": "DS.d817.s1.e5",
"normalized": []
},
{
"id": "DS.d817.s1.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d817.s1.e0",
"arg2_id": "DS.d817.s1.e4",
"normalized": []
}
] |
DS.d818 | 18710402 | [
{
"id": "DS.d818.s0",
"type": "",
"text": [
"Intracellular concentrations of Ca(2+) modulate the strength of signal and alter the outcomes of cytotoxic T-lymphocyte antigen-4 (CD152)-CD80/CD86 interactions in CD4 (+) T lymphocytes."
],
"offsets": [
[
0,
186
]
]
},
{
"id": "DS.d818.s1",
"type": "",
"text": [
"During activation with PMA and low amounts of I, intracellular concentrations of calcium ((Ca(2+))(i)) were greatly reduced upon CTLA-4-CD80/CD86 blockade."
],
"offsets": [
[
187,
342
]
]
},
{
"id": "DS.d818.s2",
"type": "",
"text": [
"Further experiments demonstrated that CTLA-4-CD80/CD86 interactions reduced cell cycling upon activation with PMA and high amounts of I or TG (high SOS) but the opposite occurred with PMA and low amounts of I or TG (low SOS)."
],
"offsets": [
[
343,
568
]
]
}
] | [
{
"id": "DS.d818.s0.e0",
"type": "compound",
"text": [
"Ca(2"
],
"offsets": [
[
32,
36
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "271"
}
]
},
{
"id": "DS.d818.s0.e1",
"type": "protein",
"text": [
"antigen-4"
],
"offsets": [
[
120,
129
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P31522"
},
{
"db_name": "UniProt",
"db_id": "Q26721"
},
{
"db_name": "UniProt",
"db_id": "Q56982"
}
]
},
{
"id": "DS.d818.s0.e2",
"type": "protein",
"text": [
"CD152"
],
"offsets": [
[
131,
136
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P16410"
}
]
},
{
"id": "DS.d818.s0.e3",
"type": "protein",
"text": [
"CD80"
],
"offsets": [
[
138,
142
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P33681"
},
{
"db_name": "UniProt",
"db_id": "P42070"
}
]
},
{
"id": "DS.d818.s0.e4",
"type": "protein",
"text": [
"CD86"
],
"offsets": [
[
143,
147
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P42071"
},
{
"db_name": "UniProt",
"db_id": "P42081"
}
]
},
{
"id": "DS.d818.s1.e0",
"type": "compound",
"text": [
"PMA"
],
"offsets": [
[
210,
213
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "27924"
},
{
"db_name": "PubChem",
"db_id": "122634"
},
{
"db_name": "PubChem",
"db_id": "22833501"
}
]
},
{
"id": "DS.d818.s1.e1",
"type": "compound",
"text": [
"Ca(2"
],
"offsets": [
[
278,
282
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "271"
}
]
},
{
"id": "DS.d818.s1.e2",
"type": "protein",
"text": [
"CTLA-4"
],
"offsets": [
[
316,
322
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P09793"
},
{
"db_name": "UniProt",
"db_id": "P16410"
},
{
"db_name": "UniProt",
"db_id": "P42072"
},
{
"db_name": "UniProt",
"db_id": "Q9MYX7"
},
{
"db_name": "UniProt",
"db_id": "Q9XSI1"
}
]
},
{
"id": "DS.d818.s1.e3",
"type": "protein",
"text": [
"CD80"
],
"offsets": [
[
323,
327
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P33681"
},
{
"db_name": "UniProt",
"db_id": "P42070"
}
]
},
{
"id": "DS.d818.s1.e4",
"type": "protein",
"text": [
"CD86"
],
"offsets": [
[
328,
332
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P42071"
},
{
"db_name": "UniProt",
"db_id": "P42081"
}
]
},
{
"id": "DS.d818.s2.e0",
"type": "protein",
"text": [
"CTLA-4"
],
"offsets": [
[
381,
387
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P09793"
},
{
"db_name": "UniProt",
"db_id": "P16410"
},
{
"db_name": "UniProt",
"db_id": "P42072"
},
{
"db_name": "UniProt",
"db_id": "Q9MYX7"
},
{
"db_name": "UniProt",
"db_id": "Q9XSI1"
}
]
},
{
"id": "DS.d818.s2.e1",
"type": "protein",
"text": [
"CD80"
],
"offsets": [
[
388,
392
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P33681"
},
{
"db_name": "UniProt",
"db_id": "P42070"
}
]
},
{
"id": "DS.d818.s2.e2",
"type": "protein",
"text": [
"CD86"
],
"offsets": [
[
393,
397
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P42071"
},
{
"db_name": "UniProt",
"db_id": "P42081"
}
]
},
{
"id": "DS.d818.s2.e3",
"type": "compound",
"text": [
"PMA"
],
"offsets": [
[
453,
456
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "27924"
},
{
"db_name": "PubChem",
"db_id": "122634"
},
{
"db_name": "PubChem",
"db_id": "22833501"
}
]
},
{
"id": "DS.d818.s2.e4",
"type": "compound",
"text": [
"SOS"
],
"offsets": [
[
491,
494
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "8885"
}
]
},
{
"id": "DS.d818.s2.e5",
"type": "compound",
"text": [
"PMA"
],
"offsets": [
[
527,
530
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "27924"
},
{
"db_name": "PubChem",
"db_id": "122634"
},
{
"db_name": "PubChem",
"db_id": "22833501"
}
]
},
{
"id": "DS.d818.s2.e6",
"type": "compound",
"text": [
"SOS"
],
"offsets": [
[
563,
566
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "8885"
}
]
}
] | [] | [] | [
{
"id": "DS.d818.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s0.e0",
"arg2_id": "DS.d818.s0.e3",
"normalized": []
},
{
"id": "DS.d818.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s0.e0",
"arg2_id": "DS.d818.s0.e4",
"normalized": []
},
{
"id": "DS.d818.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s0.e0",
"arg2_id": "DS.d818.s0.e1",
"normalized": []
},
{
"id": "DS.d818.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s0.e0",
"arg2_id": "DS.d818.s0.e2",
"normalized": []
},
{
"id": "DS.d818.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s1.e0",
"arg2_id": "DS.d818.s1.e3",
"normalized": []
},
{
"id": "DS.d818.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s1.e1",
"arg2_id": "DS.d818.s1.e4",
"normalized": []
},
{
"id": "DS.d818.s1.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s1.e0",
"arg2_id": "DS.d818.s1.e4",
"normalized": []
},
{
"id": "DS.d818.s1.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s1.e0",
"arg2_id": "DS.d818.s1.e2",
"normalized": []
},
{
"id": "DS.d818.s1.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s1.e1",
"arg2_id": "DS.d818.s1.e3",
"normalized": []
},
{
"id": "DS.d818.s1.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s1.e1",
"arg2_id": "DS.d818.s1.e2",
"normalized": []
},
{
"id": "DS.d818.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s2.e3",
"arg2_id": "DS.d818.s2.e1",
"normalized": []
},
{
"id": "DS.d818.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s2.e4",
"arg2_id": "DS.d818.s2.e1",
"normalized": []
},
{
"id": "DS.d818.s2.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s2.e4",
"arg2_id": "DS.d818.s2.e0",
"normalized": []
},
{
"id": "DS.d818.s2.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s2.e3",
"arg2_id": "DS.d818.s2.e2",
"normalized": []
},
{
"id": "DS.d818.s2.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s2.e3",
"arg2_id": "DS.d818.s2.e0",
"normalized": []
},
{
"id": "DS.d818.s2.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d818.s2.e4",
"arg2_id": "DS.d818.s2.e2",
"normalized": []
}
] |
DS.d819 | 18710604 | [
{
"id": "DS.d819.s0",
"type": "",
"text": [
"FSO decreased fasting glucose by 20 % and liver weights by 37 % compared with those in the CLA group; it maintained circulating insulin, HOMA1-IR and HOMA1 for beta cell function at levels found in the control group."
],
"offsets": [
[
0,
216
]
]
}
] | [
{
"id": "DS.d819.s0.e0",
"type": "compound",
"text": [
"FSO"
],
"offsets": [
[
0,
3
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5288258"
}
]
},
{
"id": "DS.d819.s0.e1",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
22,
29
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d819.s0.e2",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
128,
135
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
}
] | [] | [] | [
{
"id": "DS.d819.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d819.s0.e0",
"arg2_id": "DS.d819.s0.e2",
"normalized": []
}
] |
DS.d820 | 18710606 | [
{
"id": "DS.d820.s0",
"type": "",
"text": [
"Animal evidence indicates that green tea may modulate insulin sensitivity, with epigallocatechin-3-gallate (EGCG) proposed as a likely health-promoting component."
],
"offsets": [
[
0,
162
]
]
},
{
"id": "DS.d820.s1",
"type": "",
"text": [
"The purpose of this study was to investigate the effect of dietary supplementation with EGCG on insulin resistance and associated metabolic risk factors in man."
],
"offsets": [
[
163,
323
]
]
},
{
"id": "DS.d820.s2",
"type": "",
"text": [
"EGCG treatment had no effect on insulin sensitivity, insulin secretion or glucose tolerance but did reduce diastolic blood pressure (mean change: placebo-0.058 (se 0.75) mmHg; EGCG-2.68 (se 0.72) mmHg; P = 0.014)."
],
"offsets": [
[
324,
537
]
]
},
{
"id": "DS.d820.s3",
"type": "",
"text": [
"In conclusion, regular intake of EGCG had no effect on insulin resistance but did result in a modest reduction in diastolic blood pressure."
],
"offsets": [
[
538,
677
]
]
}
] | [
{
"id": "DS.d820.s0.e0",
"type": "compound",
"text": [
"green tea"
],
"offsets": [
[
31,
40
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4630"
}
]
},
{
"id": "DS.d820.s0.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
54,
61
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d820.s0.e2",
"type": "compound",
"text": [
"epigallocatechin-3-gallate"
],
"offsets": [
[
80,
106
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65064"
}
]
},
{
"id": "DS.d820.s0.e3",
"type": "compound",
"text": [
"EGCG"
],
"offsets": [
[
108,
112
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65064"
}
]
},
{
"id": "DS.d820.s1.e0",
"type": "compound",
"text": [
"EGCG"
],
"offsets": [
[
251,
255
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65064"
}
]
},
{
"id": "DS.d820.s1.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
259,
266
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d820.s2.e0",
"type": "compound",
"text": [
"EGCG"
],
"offsets": [
[
324,
328
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65064"
}
]
},
{
"id": "DS.d820.s2.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
356,
363
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d820.s2.e2",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
377,
384
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d820.s2.e3",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
398,
405
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d820.s2.e4",
"type": "compound",
"text": [
"EGCG"
],
"offsets": [
[
500,
504
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65064"
}
]
},
{
"id": "DS.d820.s3.e0",
"type": "compound",
"text": [
"EGCG"
],
"offsets": [
[
571,
575
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65064"
}
]
},
{
"id": "DS.d820.s3.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
593,
600
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
}
] | [] | [] | [
{
"id": "DS.d820.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d820.s1.e0",
"arg2_id": "DS.d820.s1.e1",
"normalized": []
}
] |
DS.d821 | 18710702 | [
{
"id": "DS.d821.s0",
"type": "",
"text": [
"We found that postovulatory administration of 1.5 mg of levonorgestrel to women with a subsequent or existing early pregnancy did not affect the immunohistochemical expressions of estrogen receptors (ER (alpha), ER (beta)), P receptors (PR(B), PR(A+B)), androgen receptor (AR), or proliferation index Ki67 in the first-trimester decidua and chorionic villi."
],
"offsets": [
[
0,
357
]
]
}
] | [
{
"id": "DS.d821.s0.e0",
"type": "compound",
"text": [
"levonorgestrel"
],
"offsets": [
[
56,
70
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "13109"
}
]
},
{
"id": "DS.d821.s0.e1",
"type": "protein",
"text": [
"estrogen receptors"
],
"offsets": [
[
180,
198
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O42132"
},
{
"db_name": "UniProt",
"db_id": "P03372"
},
{
"db_name": "UniProt",
"db_id": "P06211"
},
{
"db_name": "UniProt",
"db_id": "P06212"
},
{
"db_name": "UniProt",
"db_id": "P16058"
},
{
"db_name": "UniProt",
"db_id": "P19785"
},
{
"db_name": "UniProt",
"db_id": "P49884"
},
{
"db_name": "UniProt",
"db_id": "P49885"
},
{
"db_name": "UniProt",
"db_id": "P49886"
},
{
"db_name": "UniProt",
"db_id": "P50240"
},
{
"db_name": "UniProt",
"db_id": "P50241"
},
{
"db_name": "UniProt",
"db_id": "P50242"
},
{
"db_name": "UniProt",
"db_id": "P57717"
},
{
"db_name": "UniProt",
"db_id": "P57753"
},
{
"db_name": "UniProt",
"db_id": "P81559"
},
{
"db_name": "UniProt",
"db_id": "Q29040"
},
{
"db_name": "UniProt",
"db_id": "Q53AD2"
},
{
"db_name": "UniProt",
"db_id": "Q91250"
},
{
"db_name": "UniProt",
"db_id": "Q91424"
},
{
"db_name": "UniProt",
"db_id": "Q9PVZ9"
},
{
"db_name": "UniProt",
"db_id": "Q9QZJ5"
},
{
"db_name": "UniProt",
"db_id": "Q9TV98"
},
{
"db_name": "UniProt",
"db_id": "Q9YH33"
},
{
"db_name": "UniProt",
"db_id": "Q9YHT3"
},
{
"db_name": "UniProt",
"db_id": "Q9YHZ7"
}
]
},
{
"id": "DS.d821.s0.e2",
"type": "protein",
"text": [
"androgen receptor"
],
"offsets": [
[
254,
271
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O97775"
},
{
"db_name": "UniProt",
"db_id": "O97776"
},
{
"db_name": "UniProt",
"db_id": "O97952"
},
{
"db_name": "UniProt",
"db_id": "O97960"
},
{
"db_name": "UniProt",
"db_id": "P10275"
},
{
"db_name": "UniProt",
"db_id": "P15207"
},
{
"db_name": "UniProt",
"db_id": "P19091"
},
{
"db_name": "UniProt",
"db_id": "P49699"
},
{
"db_name": "UniProt",
"db_id": "Q6QT55"
},
{
"db_name": "UniProt",
"db_id": "Q7T1K4"
},
{
"db_name": "UniProt",
"db_id": "Q8MIK0"
},
{
"db_name": "UniProt",
"db_id": "Q9GKL7"
},
{
"db_name": "UniProt",
"db_id": "Q9TT90"
}
]
}
] | [] | [] | [] |
DS.d822 | 18710819 | [
{
"id": "DS.d822.s0",
"type": "",
"text": [
"5-FU effect on HS cell viability was markedly reduced in hypoxic condition without an induction of chemoresistant related protein, P-glycoprotein."
],
"offsets": [
[
0,
146
]
]
}
] | [
{
"id": "DS.d822.s0.e0",
"type": "compound",
"text": [
"5-FU"
],
"offsets": [
[
0,
4
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3385"
}
]
},
{
"id": "DS.d822.s0.e1",
"type": "protein",
"text": [
"glycoprotein"
],
"offsets": [
[
133,
145
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P08163"
}
]
}
] | [] | [] | [] |
DS.d823 | 18710908 | [
{
"id": "DS.d823.s0",
"type": "",
"text": [
"High-level toxin production occurred after detectable spore germination in all experiments except those with C. difficile PCR ribotype 027 and moxifloxacin, in which marked cytotoxin production preceded detectable germination, which coincided with isolate recovery on fluoroquinolone-containing medium."
],
"offsets": [
[
0,
302
]
]
}
] | [
{
"id": "DS.d823.s0.e0",
"type": "compound",
"text": [
"moxifloxacin"
],
"offsets": [
[
143,
155
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "152946"
}
]
},
{
"id": "DS.d823.s0.e1",
"type": "protein",
"text": [
"cytotoxin"
],
"offsets": [
[
173,
182
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P07845"
},
{
"db_name": "UniProt",
"db_id": "P81662"
}
]
}
] | [] | [] | [] |
DS.d824 | 18711728 | [
{
"id": "DS.d824.s0",
"type": "",
"text": [
"Furthermore, Ngb overexpression reduced superoxide anion generation after H/R, whereas glutathione levels were significantly improved compared with WT controls."
],
"offsets": [
[
0,
160
]
]
}
] | [
{
"id": "DS.d824.s0.e0",
"type": "protein",
"text": [
"Ngb"
],
"offsets": [
[
13,
16
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q90YJ2"
},
{
"db_name": "UniProt",
"db_id": "Q99JA8"
},
{
"db_name": "UniProt",
"db_id": "Q9ER97"
}
]
},
{
"id": "DS.d824.s0.e1",
"type": "compound",
"text": [
"superoxide"
],
"offsets": [
[
40,
50
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5359597"
}
]
},
{
"id": "DS.d824.s0.e2",
"type": "compound",
"text": [
"glutathione"
],
"offsets": [
[
87,
98
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
}
] | [] | [] | [
{
"id": "DS.d824.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d824.s0.e1",
"arg2_id": "DS.d824.s0.e0",
"normalized": []
},
{
"id": "DS.d824.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d824.s0.e2",
"arg2_id": "DS.d824.s0.e0",
"normalized": []
}
] |
DS.d825 | 18711746 | [
{
"id": "DS.d825.s0",
"type": "",
"text": [
"Our previous studies have shown that serotonin (5-HT) altered under diabetic condition was accompanied by alterations of protein kinase C-alpha (PKC-alpha) and CaMKII, and those alterations were reversed after insulin administration."
],
"offsets": [
[
0,
233
]
]
},
{
"id": "DS.d825.s1",
"type": "",
"text": [
"The current study showed that alloxan-induced diabetic animals revealed hyperglycemia and was associated with an increase in the content of 5-HT, PKC-alpha expression and PKC 0.05) simultaneously in striatum (ST), midbrain (MB), pons medulla (PM), cerebellum (CB), and cerebral cortex (CCX) from 7 days to 60 days."
],
"offsets": [
[
234,
548
]
]
},
{
"id": "DS.d825.s2",
"type": "",
"text": [
"Although the 5-HT levels in hippocampus (HC) and hypothalamus (HT) were not altered, the PKC-alpha expression and PKC 0.05) in level in HC."
],
"offsets": [
[
549,
688
]
]
}
] | [
{
"id": "DS.d825.s0.e0",
"type": "compound",
"text": [
"serotonin"
],
"offsets": [
[
37,
46
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5202"
}
]
},
{
"id": "DS.d825.s0.e1",
"type": "compound",
"text": [
"5-HT"
],
"offsets": [
[
48,
52
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5202"
}
]
},
{
"id": "DS.d825.s0.e2",
"type": "protein",
"text": [
"protein kinase C"
],
"offsets": [
[
121,
137
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P13678"
},
{
"db_name": "UniProt",
"db_id": "Q25378"
}
]
},
{
"id": "DS.d825.s0.e3",
"type": "protein",
"text": [
"PKC-alpha"
],
"offsets": [
[
145,
154
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P04409"
},
{
"db_name": "UniProt",
"db_id": "P05696"
},
{
"db_name": "UniProt",
"db_id": "P10102"
},
{
"db_name": "UniProt",
"db_id": "P17252"
},
{
"db_name": "UniProt",
"db_id": "P20444"
}
]
},
{
"id": "DS.d825.s0.e4",
"type": "protein",
"text": [
"CaMKII"
],
"offsets": [
[
160,
166
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q00168"
}
]
},
{
"id": "DS.d825.s0.e5",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
210,
217
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d825.s1.e0",
"type": "compound",
"text": [
"alloxan"
],
"offsets": [
[
264,
271
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5781"
}
]
},
{
"id": "DS.d825.s1.e1",
"type": "compound",
"text": [
"5-HT"
],
"offsets": [
[
374,
378
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5202"
}
]
},
{
"id": "DS.d825.s1.e2",
"type": "protein",
"text": [
"PKC-alpha"
],
"offsets": [
[
380,
389
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P04409"
},
{
"db_name": "UniProt",
"db_id": "P05696"
},
{
"db_name": "UniProt",
"db_id": "P10102"
},
{
"db_name": "UniProt",
"db_id": "P17252"
},
{
"db_name": "UniProt",
"db_id": "P20444"
}
]
},
{
"id": "DS.d825.s1.e3",
"type": "protein",
"text": [
"PKC"
],
"offsets": [
[
380,
383
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05130"
},
{
"db_name": "UniProt",
"db_id": "P13677"
},
{
"db_name": "UniProt",
"db_id": "P13678"
},
{
"db_name": "UniProt",
"db_id": "P34722"
}
]
},
{
"id": "DS.d825.s1.e4",
"type": "protein",
"text": [
"pons"
],
"offsets": [
[
463,
467
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P52430"
},
{
"db_name": "UniProt",
"db_id": "P55159"
}
]
},
{
"id": "DS.d825.s2.e0",
"type": "compound",
"text": [
"5-HT"
],
"offsets": [
[
562,
566
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5202"
}
]
},
{
"id": "DS.d825.s2.e1",
"type": "protein",
"text": [
"PKC-alpha"
],
"offsets": [
[
638,
647
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P04409"
},
{
"db_name": "UniProt",
"db_id": "P05696"
},
{
"db_name": "UniProt",
"db_id": "P10102"
},
{
"db_name": "UniProt",
"db_id": "P17252"
},
{
"db_name": "UniProt",
"db_id": "P20444"
}
]
},
{
"id": "DS.d825.s2.e2",
"type": "protein",
"text": [
"PKC"
],
"offsets": [
[
638,
641
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05130"
},
{
"db_name": "UniProt",
"db_id": "P13677"
},
{
"db_name": "UniProt",
"db_id": "P13678"
},
{
"db_name": "UniProt",
"db_id": "P34722"
}
]
}
] | [] | [] | [
{
"id": "DS.d825.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s0.e0",
"arg2_id": "DS.d825.s0.e3",
"normalized": []
},
{
"id": "DS.d825.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s0.e0",
"arg2_id": "DS.d825.s0.e5",
"normalized": []
},
{
"id": "DS.d825.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s0.e1",
"arg2_id": "DS.d825.s0.e3",
"normalized": []
},
{
"id": "DS.d825.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s0.e1",
"arg2_id": "DS.d825.s0.e4",
"normalized": []
},
{
"id": "DS.d825.s0.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s0.e1",
"arg2_id": "DS.d825.s0.e2",
"normalized": []
},
{
"id": "DS.d825.s0.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s0.e1",
"arg2_id": "DS.d825.s0.e5",
"normalized": []
},
{
"id": "DS.d825.s0.i6",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s0.e0",
"arg2_id": "DS.d825.s0.e2",
"normalized": []
},
{
"id": "DS.d825.s0.i7",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s0.e0",
"arg2_id": "DS.d825.s0.e4",
"normalized": []
},
{
"id": "DS.d825.s1.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s1.e0",
"arg2_id": "DS.d825.s1.e2",
"normalized": []
},
{
"id": "DS.d825.s1.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d825.s1.e0",
"arg2_id": "DS.d825.s1.e3",
"normalized": []
}
] |
DS.d826 | 18711749 | [
{
"id": "DS.d826.s0",
"type": "",
"text": [
"We tested the hypothesis that a nitric oxide donor, DETA-NONOate, up-regulates stromal cell-derived factor-1 (SDF1) and angiopoietin 1 (Ang1) in the ischemic brain and their respective receptors chemokine CXC motif receptor 4 (CXCR4) and Tie2 in the subventricular zone (SVZ) and thereby promote SVZ neuroblast cell migration after stroke."
],
"offsets": [
[
0,
339
]
]
},
{
"id": "DS.d826.s1",
"type": "",
"text": [
"To elucidate whether SDF1/CXCR4 and Ang1/Tie2 pathways mediate DETA-NONOate-induced SVZ migration after stroke, SDF1alpha, Ang1 peptide, a specific antagonist of CXCR4 (AMD3100), and a neutralizing antibody of Tie2 (anti-Tie2) were used in vitro."
],
"offsets": [
[
340,
586
]
]
},
{
"id": "DS.d826.s2",
"type": "",
"text": [
"DETA-NONOate significantly increased the expression of SDF1 and Ang1 in the ischemic border and up-regulated CXCR4 and Tie2 in the SVZ compared with MCAo control."
],
"offsets": [
[
587,
749
]
]
},
{
"id": "DS.d826.s3",
"type": "",
"text": [
"Our data indicate that treatment of stroke with a nitric oxide donor up-regulates SDF1/CXCR4 and Ang1/Tie2 pathways and thereby likely increases SVZ neuroblast cell migration."
],
"offsets": [
[
750,
925
]
]
}
] | [
{
"id": "DS.d826.s0.e0",
"type": "compound",
"text": [
"nitric oxide"
],
"offsets": [
[
32,
44
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "145068"
}
]
},
{
"id": "DS.d826.s0.e1",
"type": "compound",
"text": [
"DETA-NONOate"
],
"offsets": [
[
52,
64
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1606"
}
]
},
{
"id": "DS.d826.s0.e2",
"type": "protein",
"text": [
"SDF1"
],
"offsets": [
[
110,
114
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62657"
},
{
"db_name": "UniProt",
"db_id": "P48061"
}
]
},
{
"id": "DS.d826.s0.e3",
"type": "protein",
"text": [
"Ang1"
],
"offsets": [
[
136,
140
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P21570"
}
]
},
{
"id": "DS.d826.s0.e4",
"type": "protein",
"text": [
"CXCR4"
],
"offsets": [
[
227,
232
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62747"
},
{
"db_name": "UniProt",
"db_id": "P25930"
},
{
"db_name": "UniProt",
"db_id": "P56491"
},
{
"db_name": "UniProt",
"db_id": "P56498"
},
{
"db_name": "UniProt",
"db_id": "P61072"
},
{
"db_name": "UniProt",
"db_id": "P61073"
},
{
"db_name": "UniProt",
"db_id": "P79394"
},
{
"db_name": "UniProt",
"db_id": "Q28474"
},
{
"db_name": "UniProt",
"db_id": "Q28553"
},
{
"db_name": "UniProt",
"db_id": "Q3LSL6"
},
{
"db_name": "UniProt",
"db_id": "Q764M9"
},
{
"db_name": "UniProt",
"db_id": "Q7YS92"
},
{
"db_name": "UniProt",
"db_id": "Q8HZU0"
},
{
"db_name": "UniProt",
"db_id": "Q8HZU1"
},
{
"db_name": "UniProt",
"db_id": "Q9TSQ8"
}
]
},
{
"id": "DS.d826.s0.e5",
"type": "protein",
"text": [
"Tie2"
],
"offsets": [
[
238,
242
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O73791"
},
{
"db_name": "UniProt",
"db_id": "Q02858"
}
]
},
{
"id": "DS.d826.s1.e0",
"type": "protein",
"text": [
"SDF1"
],
"offsets": [
[
361,
365
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62657"
},
{
"db_name": "UniProt",
"db_id": "P48061"
}
]
},
{
"id": "DS.d826.s1.e1",
"type": "compound",
"text": [
"DETA-NONOate"
],
"offsets": [
[
403,
415
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1606"
}
]
},
{
"id": "DS.d826.s1.e2",
"type": "compound",
"text": [
"peptide, a"
],
"offsets": [
[
468,
478
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "52944803"
}
]
},
{
"id": "DS.d826.s1.e3",
"type": "compound",
"text": [
"AMD3100"
],
"offsets": [
[
509,
516
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65015"
}
]
},
{
"id": "DS.d826.s2.e0",
"type": "compound",
"text": [
"DETA-NONOate"
],
"offsets": [
[
587,
599
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1606"
}
]
},
{
"id": "DS.d826.s2.e1",
"type": "protein",
"text": [
"SDF1"
],
"offsets": [
[
642,
646
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62657"
},
{
"db_name": "UniProt",
"db_id": "P48061"
}
]
},
{
"id": "DS.d826.s2.e2",
"type": "protein",
"text": [
"Ang1"
],
"offsets": [
[
651,
655
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P21570"
}
]
},
{
"id": "DS.d826.s2.e3",
"type": "protein",
"text": [
"CXCR4"
],
"offsets": [
[
696,
701
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62747"
},
{
"db_name": "UniProt",
"db_id": "P25930"
},
{
"db_name": "UniProt",
"db_id": "P56491"
},
{
"db_name": "UniProt",
"db_id": "P56498"
},
{
"db_name": "UniProt",
"db_id": "P61072"
},
{
"db_name": "UniProt",
"db_id": "P61073"
},
{
"db_name": "UniProt",
"db_id": "P79394"
},
{
"db_name": "UniProt",
"db_id": "Q28474"
},
{
"db_name": "UniProt",
"db_id": "Q28553"
},
{
"db_name": "UniProt",
"db_id": "Q3LSL6"
},
{
"db_name": "UniProt",
"db_id": "Q764M9"
},
{
"db_name": "UniProt",
"db_id": "Q7YS92"
},
{
"db_name": "UniProt",
"db_id": "Q8HZU0"
},
{
"db_name": "UniProt",
"db_id": "Q8HZU1"
},
{
"db_name": "UniProt",
"db_id": "Q9TSQ8"
}
]
},
{
"id": "DS.d826.s2.e4",
"type": "protein",
"text": [
"Tie2"
],
"offsets": [
[
706,
710
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O73791"
},
{
"db_name": "UniProt",
"db_id": "Q02858"
}
]
},
{
"id": "DS.d826.s3.e0",
"type": "compound",
"text": [
"nitric oxide"
],
"offsets": [
[
800,
812
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "145068"
}
]
},
{
"id": "DS.d826.s3.e1",
"type": "protein",
"text": [
"SDF1"
],
"offsets": [
[
832,
836
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62657"
},
{
"db_name": "UniProt",
"db_id": "P48061"
}
]
},
{
"id": "DS.d826.s3.e2",
"type": "protein",
"text": [
"CXCR4"
],
"offsets": [
[
837,
842
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62747"
},
{
"db_name": "UniProt",
"db_id": "P25930"
},
{
"db_name": "UniProt",
"db_id": "P56491"
},
{
"db_name": "UniProt",
"db_id": "P56498"
},
{
"db_name": "UniProt",
"db_id": "P61072"
},
{
"db_name": "UniProt",
"db_id": "P61073"
},
{
"db_name": "UniProt",
"db_id": "P79394"
},
{
"db_name": "UniProt",
"db_id": "Q28474"
},
{
"db_name": "UniProt",
"db_id": "Q28553"
},
{
"db_name": "UniProt",
"db_id": "Q3LSL6"
},
{
"db_name": "UniProt",
"db_id": "Q764M9"
},
{
"db_name": "UniProt",
"db_id": "Q7YS92"
},
{
"db_name": "UniProt",
"db_id": "Q8HZU0"
},
{
"db_name": "UniProt",
"db_id": "Q8HZU1"
},
{
"db_name": "UniProt",
"db_id": "Q9TSQ8"
}
]
},
{
"id": "DS.d826.s3.e3",
"type": "protein",
"text": [
"Ang1"
],
"offsets": [
[
847,
851
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P21570"
}
]
},
{
"id": "DS.d826.s3.e4",
"type": "protein",
"text": [
"Tie2"
],
"offsets": [
[
852,
856
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O73791"
},
{
"db_name": "UniProt",
"db_id": "Q02858"
}
]
}
] | [] | [] | [
{
"id": "DS.d826.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s0.e1",
"arg2_id": "DS.d826.s0.e4",
"normalized": []
},
{
"id": "DS.d826.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s0.e1",
"arg2_id": "DS.d826.s0.e2",
"normalized": []
},
{
"id": "DS.d826.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s0.e0",
"arg2_id": "DS.d826.s0.e5",
"normalized": []
},
{
"id": "DS.d826.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s0.e0",
"arg2_id": "DS.d826.s0.e2",
"normalized": []
},
{
"id": "DS.d826.s0.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s0.e0",
"arg2_id": "DS.d826.s0.e3",
"normalized": []
},
{
"id": "DS.d826.s0.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s0.e1",
"arg2_id": "DS.d826.s0.e5",
"normalized": []
},
{
"id": "DS.d826.s0.i6",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s0.e1",
"arg2_id": "DS.d826.s0.e3",
"normalized": []
},
{
"id": "DS.d826.s0.i7",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s0.e0",
"arg2_id": "DS.d826.s0.e4",
"normalized": []
},
{
"id": "DS.d826.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s1.e3",
"arg2_id": "DS.d826.s1.e0",
"normalized": []
},
{
"id": "DS.d826.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s1.e1",
"arg2_id": "DS.d826.s1.e0",
"normalized": []
},
{
"id": "DS.d826.s1.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s1.e2",
"arg2_id": "DS.d826.s1.e0",
"normalized": []
},
{
"id": "DS.d826.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s2.e0",
"arg2_id": "DS.d826.s2.e3",
"normalized": []
},
{
"id": "DS.d826.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s2.e0",
"arg2_id": "DS.d826.s2.e4",
"normalized": []
},
{
"id": "DS.d826.s2.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s2.e0",
"arg2_id": "DS.d826.s2.e1",
"normalized": []
},
{
"id": "DS.d826.s2.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s2.e0",
"arg2_id": "DS.d826.s2.e2",
"normalized": []
},
{
"id": "DS.d826.s3.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s3.e0",
"arg2_id": "DS.d826.s3.e4",
"normalized": []
},
{
"id": "DS.d826.s3.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s3.e0",
"arg2_id": "DS.d826.s3.e3",
"normalized": []
},
{
"id": "DS.d826.s3.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s3.e0",
"arg2_id": "DS.d826.s3.e1",
"normalized": []
},
{
"id": "DS.d826.s3.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d826.s3.e0",
"arg2_id": "DS.d826.s3.e2",
"normalized": []
}
] |
DS.d827 | 18711750 | [
{
"id": "DS.d827.s0",
"type": "",
"text": [
"The MEK inhibitor PD98059 did not inhibit neurite outgrowth, and Y-27632 and staurosporine did not induce ERK phosphorylation, suggesting that the inhibitory effect of ODQ on neurite outgrowth is independent of the ERK signaling pathway."
],
"offsets": [
[
0,
237
]
]
}
] | [
{
"id": "DS.d827.s0.e0",
"type": "compound",
"text": [
"PD98059"
],
"offsets": [
[
18,
25
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4713"
}
]
},
{
"id": "DS.d827.s0.e1",
"type": "compound",
"text": [
"staurosporine"
],
"offsets": [
[
77,
90
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5279"
},
{
"db_name": "PubChem",
"db_id": "44259"
},
{
"db_name": "PubChem",
"db_id": "451705"
},
{
"db_name": "PubChem",
"db_id": "5311103"
},
{
"db_name": "PubChem",
"db_id": "5459111"
},
{
"db_name": "PubChem",
"db_id": "6419748"
},
{
"db_name": "PubChem",
"db_id": "6711321"
},
{
"db_name": "PubChem",
"db_id": "9956178"
},
{
"db_name": "PubChem",
"db_id": "44299148"
}
]
},
{
"id": "DS.d827.s0.e2",
"type": "protein",
"text": [
"ERK"
],
"offsets": [
[
106,
109
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P29323"
}
]
},
{
"id": "DS.d827.s0.e3",
"type": "compound",
"text": [
"ODQ"
],
"offsets": [
[
168,
171
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1456"
}
]
},
{
"id": "DS.d827.s0.e4",
"type": "protein",
"text": [
"ERK"
],
"offsets": [
[
215,
218
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P29323"
}
]
}
] | [] | [] | [] |