id
stringlengths 5
8
| document_id
stringlengths 8
8
| passages
list | entities
list | events
list | coreferences
list | relations
list |
|---|---|---|---|---|---|---|
DS.d0 | 17003041 | [
{
"id": "DS.d0.s0",
"text": [
"Bestrophin-1 enables Ca2+-activated Cl-conductance in epithelia."
],
"offsets": [
[
0,
64
]
],
"type": ""
},
{
"id": "DS.d0.s1",
"text": [
"Calcium-dependent Cl (-) currents were activated by ATP in HEK293 cells expressing BEST1."
],
"offsets": [
[
65,
154
]
],
"type": ""
}
] | [
{
"id": "DS.d0.s0.e0",
"type": "protein",
"text": [
"Bestrophin-1"
],
"offsets": [
[
0,
12
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O76090"
},
{
"db_name": "UniProt",
"db_id": "O88870"
},
{
"db_name": "UniProt",
"db_id": "Q21973"
},
{
"db_name": "UniProt",
"db_id": "Q6UY87"
},
{
"db_name": "UniProt",
"db_id": "Q8WMR7"
}
]
},
{
"id": "DS.d0.s0.e1",
"type": "compound",
"text": [
"Cl"
],
"offsets": [
[
36,
38
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "312"
}
]
},
{
"id": "DS.d0.s1.e0",
"type": "compound",
"text": [
"Cl"
],
"offsets": [
[
83,
85
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "312"
}
]
},
{
"id": "DS.d0.s1.e1",
"type": "compound",
"text": [
"ATP"
],
"offsets": [
[
117,
120
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5957"
}
]
},
{
"id": "DS.d0.s1.e2",
"type": "protein",
"text": [
"BEST1"
],
"offsets": [
[
148,
153
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O76090"
},
{
"db_name": "UniProt",
"db_id": "Q6UY87"
},
{
"db_name": "UniProt",
"db_id": "Q8WMR7"
}
]
}
] | [] | [] | [
{
"id": "DS.d0.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d0.s0.e1",
"arg2_id": "DS.d0.s0.e0",
"normalized": []
}
] |
DS.d1 | 17321121 | [
{
"id": "DS.d1.s0",
"text": [
"The absorption spectrum of the hydrogenase enzyme showed an absorption peak at 425nm indicating that the enzyme had iron-sulfur clusters."
],
"offsets": [
[
0,
137
]
],
"type": ""
}
] | [
{
"id": "DS.d1.s0.e0",
"type": "protein",
"text": [
"hydrogenase"
],
"offsets": [
[
31,
42
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P80509"
},
{
"db_name": "UniProt",
"db_id": "P80510"
}
]
},
{
"id": "DS.d1.s0.e1",
"type": "compound",
"text": [
"sulfur"
],
"offsets": [
[
121,
127
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "402"
}
]
}
] | [] | [] | [
{
"id": "DS.d1.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d1.s0.e1",
"arg2_id": "DS.d1.s0.e0",
"normalized": []
}
] |
DS.d2 | 17403602 | [
{
"id": "DS.d2.s0",
"text": [
"When Vitreoscilla were grown in medium containing 60mM sodium nitrite under both normal and limited aeration conditions, the levels of Vitreoscilla hemoglobin (VHb) were decreased by greater than 90%, while the levels of the terminal respiratory oxidase, cytochrome bo, were increased 350% under normal aeration and 7-23% under limited aeration."
],
"offsets": [
[
0,
345
]
],
"type": ""
}
] | [
{
"id": "DS.d2.s0.e0",
"type": "compound",
"text": [
"sodium nitrite"
],
"offsets": [
[
55,
69
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "23668193"
}
]
},
{
"id": "DS.d2.s0.e1",
"type": "protein",
"text": [
"hemoglobin"
],
"offsets": [
[
148,
158
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P15160"
},
{
"db_name": "UniProt",
"db_id": "P17724"
},
{
"db_name": "UniProt",
"db_id": "P73925"
},
{
"db_name": "UniProt",
"db_id": "Q03459"
}
]
}
] | [] | [] | [
{
"id": "DS.d2.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d2.s0.e0",
"arg2_id": "DS.d2.s0.e1",
"normalized": []
}
] |
DS.d3 | 17590240 | [
{
"id": "DS.d3.s0",
"text": [
"Epigallocatechin gallate (EGCG) suppresses beta-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3 beta activation."
],
"offsets": [
[
0,
155
]
],
"type": ""
},
{
"id": "DS.d3.s1",
"text": [
"Here, we used a human neuronal cell line MC65 conditional expression of an amyloid precursor protein fragment (APP-C99) to investigate the protection mechanism of epigallocatechin gallate (EGCG), the main constituent of green tea."
],
"offsets": [
[
156,
386
]
],
"type": ""
}
] | [
{
"id": "DS.d3.s0.e0",
"type": "compound",
"text": [
"Epigallocatechin gallate (EGCG"
],
"offsets": [
[
0,
30
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65064"
}
]
},
{
"id": "DS.d3.s0.e1",
"type": "protein",
"text": [
"Abl"
],
"offsets": [
[
99,
102
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P00520"
},
{
"db_name": "UniProt",
"db_id": "P00522"
}
]
},
{
"id": "DS.d3.s0.e2",
"type": "protein",
"text": [
"FE65"
],
"offsets": [
[
103,
107
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O00213"
}
]
},
{
"id": "DS.d3.s0.e3",
"type": "protein",
"text": [
"GSK3 beta"
],
"offsets": [
[
134,
143
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P18266"
},
{
"db_name": "UniProt",
"db_id": "P49841"
},
{
"db_name": "UniProt",
"db_id": "Q5YJC2"
},
{
"db_name": "UniProt",
"db_id": "Q9WV60"
}
]
},
{
"id": "DS.d3.s1.e0",
"type": "protein",
"text": [
"APP-C99"
],
"offsets": [
[
267,
274
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P12023"
}
]
},
{
"id": "DS.d3.s1.e1",
"type": "compound",
"text": [
"epigallocatechin gallate (EGCG"
],
"offsets": [
[
319,
349
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65064"
}
]
},
{
"id": "DS.d3.s1.e2",
"type": "compound",
"text": [
"green tea"
],
"offsets": [
[
376,
385
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4630"
}
]
}
] | [] | [] | [
{
"id": "DS.d3.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d3.s0.e0",
"arg2_id": "DS.d3.s0.e3",
"normalized": []
},
{
"id": "DS.d3.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d3.s0.e0",
"arg2_id": "DS.d3.s0.e1",
"normalized": []
},
{
"id": "DS.d3.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d3.s0.e0",
"arg2_id": "DS.d3.s0.e2",
"normalized": []
}
] |
DS.d4 | 17616381 | [
{
"id": "DS.d4.s0",
"text": [
"The protease was purified to homogeneity using ammonium sulfate precipitation, and ion exchange chromatography with a fold purification of 1.8 and a recovery of 49%."
],
"offsets": [
[
0,
165
]
],
"type": ""
}
] | [
{
"id": "DS.d4.s0.e0",
"type": "protein",
"text": [
"protease"
],
"offsets": [
[
4,
12
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O41798"
},
{
"db_name": "UniProt",
"db_id": "O89290"
},
{
"db_name": "UniProt",
"db_id": "O89940"
},
{
"db_name": "UniProt",
"db_id": "O91080"
},
{
"db_name": "UniProt",
"db_id": "O93215"
},
{
"db_name": "UniProt",
"db_id": "P03311"
},
{
"db_name": "UniProt",
"db_id": "P03353"
},
{
"db_name": "UniProt",
"db_id": "P03355"
},
{
"db_name": "UniProt",
"db_id": "P03356"
},
{
"db_name": "UniProt",
"db_id": "P03362"
},
{
"db_name": "UniProt",
"db_id": "P03363"
},
{
"db_name": "UniProt",
"db_id": "P03366"
},
{
"db_name": "UniProt",
"db_id": "P03367"
},
{
"db_name": "UniProt",
"db_id": "P03369"
},
{
"db_name": "UniProt",
"db_id": "P03370"
},
{
"db_name": "UniProt",
"db_id": "P04023"
},
{
"db_name": "UniProt",
"db_id": "P04024"
},
{
"db_name": "UniProt",
"db_id": "P04323"
},
{
"db_name": "UniProt",
"db_id": "P04584"
},
{
"db_name": "UniProt",
"db_id": "P04585"
},
{
"db_name": "UniProt",
"db_id": "P04587"
},
{
"db_name": "UniProt",
"db_id": "P04588"
},
{
"db_name": "UniProt",
"db_id": "P04589"
},
{
"db_name": "UniProt",
"db_id": "P05959"
},
{
"db_name": "UniProt",
"db_id": "P05960"
},
{
"db_name": "UniProt",
"db_id": "P05961"
},
{
"db_name": "UniProt",
"db_id": "P05962"
},
{
"db_name": "UniProt",
"db_id": "P07570"
},
{
"db_name": "UniProt",
"db_id": "P0C210"
},
{
"db_name": "UniProt",
"db_id": "P0C211"
},
{
"db_name": "UniProt",
"db_id": "P10210"
},
{
"db_name": "UniProt",
"db_id": "P10265"
},
{
"db_name": "UniProt",
"db_id": "P10270"
},
{
"db_name": "UniProt",
"db_id": "P10271"
},
{
"db_name": "UniProt",
"db_id": "P10272"
},
{
"db_name": "UniProt",
"db_id": "P10273"
},
{
"db_name": "UniProt",
"db_id": "P10274"
},
{
"db_name": "UniProt",
"db_id": "P10394"
},
{
"db_name": "UniProt",
"db_id": "P10978"
},
{
"db_name": "UniProt",
"db_id": "P11227"
},
{
"db_name": "UniProt",
"db_id": "P11365"
},
{
"db_name": "UniProt",
"db_id": "P12451"
},
{
"db_name": "UniProt",
"db_id": "P12497"
},
{
"db_name": "UniProt",
"db_id": "P12498"
},
{
"db_name": "UniProt",
"db_id": "P12499"
},
{
"db_name": "UniProt",
"db_id": "P14074"
},
{
"db_name": "UniProt",
"db_id": "P14078"
},
{
"db_name": "UniProt",
"db_id": "P15833"
},
{
"db_name": "UniProt",
"db_id": "P16046"
},
{
"db_name": "UniProt",
"db_id": "P16423"
},
{
"db_name": "UniProt",
"db_id": "P16901"
},
{
"db_name": "UniProt",
"db_id": "P17757"
},
{
"db_name": "UniProt",
"db_id": "P18042"
},
{
"db_name": "UniProt",
"db_id": "P18096"
},
{
"db_name": "UniProt",
"db_id": "P18802"
},
{
"db_name": "UniProt",
"db_id": "P19028"
},
{
"db_name": "UniProt",
"db_id": "P19199"
},
{
"db_name": "UniProt",
"db_id": "P19560"
},
{
"db_name": "UniProt",
"db_id": "P19561"
},
{
"db_name": "UniProt",
"db_id": "P20825"
},
{
"db_name": "UniProt",
"db_id": "P20875"
},
{
"db_name": "UniProt",
"db_id": "P20876"
},
{
"db_name": "UniProt",
"db_id": "P20892"
},
{
"db_name": "UniProt",
"db_id": "P21407"
},
{
"db_name": "UniProt",
"db_id": "P21414"
},
{
"db_name": "UniProt",
"db_id": "P24107"
},
{
"db_name": "UniProt",
"db_id": "P24740"
},
{
"db_name": "UniProt",
"db_id": "P26808"
},
{
"db_name": "UniProt",
"db_id": "P26809"
},
{
"db_name": "UniProt",
"db_id": "P26810"
},
{
"db_name": "UniProt",
"db_id": "P27502"
},
{
"db_name": "UniProt",
"db_id": "P28936"
},
{
"db_name": "UniProt",
"db_id": "P31822"
},
{
"db_name": "UniProt",
"db_id": "P35956"
},
{
"db_name": "UniProt",
"db_id": "P35963"
},
{
"db_name": "UniProt",
"db_id": "P51518"
},
{
"db_name": "UniProt",
"db_id": "P63119"
},
{
"db_name": "UniProt",
"db_id": "P63120"
},
{
"db_name": "UniProt",
"db_id": "P63121"
},
{
"db_name": "UniProt",
"db_id": "P63122"
},
{
"db_name": "UniProt",
"db_id": "P63123"
},
{
"db_name": "UniProt",
"db_id": "P63124"
},
{
"db_name": "UniProt",
"db_id": "P63125"
},
{
"db_name": "UniProt",
"db_id": "P63127"
},
{
"db_name": "UniProt",
"db_id": "P63128"
},
{
"db_name": "UniProt",
"db_id": "P63129"
},
{
"db_name": "UniProt",
"db_id": "P63131"
},
{
"db_name": "UniProt",
"db_id": "P84454"
},
{
"db_name": "UniProt",
"db_id": "Q09SZ9"
},
{
"db_name": "UniProt",
"db_id": "Q0R5R2"
},
{
"db_name": "UniProt",
"db_id": "Q0R5R3"
},
{
"db_name": "UniProt",
"db_id": "Q1A249"
},
{
"db_name": "UniProt",
"db_id": "Q1A267"
},
{
"db_name": "UniProt",
"db_id": "Q4U0X6"
},
{
"db_name": "UniProt",
"db_id": "Q73368"
},
{
"db_name": "UniProt",
"db_id": "Q74120"
},
{
"db_name": "UniProt",
"db_id": "Q75002"
},
{
"db_name": "UniProt",
"db_id": "Q76634"
},
{
"db_name": "UniProt",
"db_id": "Q77373"
},
{
"db_name": "UniProt",
"db_id": "Q79666"
},
{
"db_name": "UniProt",
"db_id": "Q89928"
},
{
"db_name": "UniProt",
"db_id": "Q8AII1"
},
{
"db_name": "UniProt",
"db_id": "Q8I7P9"
},
{
"db_name": "UniProt",
"db_id": "Q9IDV9"
},
{
"db_name": "UniProt",
"db_id": "Q9Q720"
},
{
"db_name": "UniProt",
"db_id": "Q9QBY3"
},
{
"db_name": "UniProt",
"db_id": "Q9QBZ1"
},
{
"db_name": "UniProt",
"db_id": "Q9QBZ5"
},
{
"db_name": "UniProt",
"db_id": "Q9QSR3"
},
{
"db_name": "UniProt",
"db_id": "Q9WC54"
},
{
"db_name": "UniProt",
"db_id": "Q9WC63"
},
{
"db_name": "UniProt",
"db_id": "Q9Y6I0"
}
]
},
{
"id": "DS.d4.s0.e1",
"type": "compound",
"text": [
"ammonium"
],
"offsets": [
[
47,
55
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "223"
}
]
},
{
"id": "DS.d4.s0.e2",
"type": "compound",
"text": [
"sulfate"
],
"offsets": [
[
56,
63
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1117"
}
]
}
] | [] | [] | [] |
DS.d5 | 17629591 | [
{
"id": "DS.d5.s0",
"text": [
"In addition, we demonstrated that Hsp20, HspB2 and HspB8 induced interleukin-6 production in cultured pericytes and astrocytes, which could be antagonized by dexamethasone, whereas other sHsps and A beta were inactive, suggesting that sHsps may be among the key mediators of the local inflammatory response associated with HCHWA-D and AD lesions."
],
"offsets": [
[
0,
346
]
],
"type": ""
}
] | [
{
"id": "DS.d5.s0.e0",
"type": "protein",
"text": [
"HspB2"
],
"offsets": [
[
41,
46
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35878"
},
{
"db_name": "UniProt",
"db_id": "Q16082"
},
{
"db_name": "UniProt",
"db_id": "Q99PR8"
}
]
},
{
"id": "DS.d5.s0.e1",
"type": "protein",
"text": [
"HspB8"
],
"offsets": [
[
51,
56
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q5EAC9"
},
{
"db_name": "UniProt",
"db_id": "Q5RAB0"
},
{
"db_name": "UniProt",
"db_id": "Q6SJQ8"
},
{
"db_name": "UniProt",
"db_id": "Q8MJ36"
},
{
"db_name": "UniProt",
"db_id": "Q9EPX0"
},
{
"db_name": "UniProt",
"db_id": "Q9JK92"
},
{
"db_name": "UniProt",
"db_id": "Q9UJY1"
}
]
},
{
"id": "DS.d5.s0.e2",
"type": "protein",
"text": [
"interleukin-6"
],
"offsets": [
[
65,
78
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P41693"
}
]
},
{
"id": "DS.d5.s0.e3",
"type": "compound",
"text": [
"dexamethasone"
],
"offsets": [
[
158,
171
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5743"
}
]
}
] | [] | [] | [
{
"id": "DS.d5.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d5.s0.e3",
"arg2_id": "DS.d5.s0.e2",
"normalized": []
}
] |
DS.d6 | 17692997 | [
{
"id": "DS.d6.s0",
"text": [
"Furthermore, dithiothreitol was found to be capable of significantly preventing the inhibitory effect of insulin on Abeta oligomer formation."
],
"offsets": [
[
0,
141
]
],
"type": ""
}
] | [
{
"id": "DS.d6.s0.e0",
"type": "compound",
"text": [
"dithiothreitol"
],
"offsets": [
[
13,
27
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "19001"
},
{
"db_name": "PubChem",
"db_id": "439196"
},
{
"db_name": "PubChem",
"db_id": "446094"
}
]
},
{
"id": "DS.d6.s0.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
105,
112
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
}
] | [] | [] | [
{
"id": "DS.d6.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d6.s0.e0",
"arg2_id": "DS.d6.s0.e1",
"normalized": []
}
] |
DS.d7 | 17719144 | [
{
"id": "DS.d7.s0",
"text": [
"The scavenger receptor, class B, type I (SR-BI) is critical in maintaining the homeostasis of cholesterol and alpha-tocopherol."
],
"offsets": [
[
0,
127
]
],
"type": ""
},
{
"id": "DS.d7.s1",
"text": [
"SR-BI binds high-density lipoproteins (HDL) and mediates the selective transfer of cholesteryl esters and alpha-tocopherol from circulating HDL to cells."
],
"offsets": [
[
128,
281
]
],
"type": ""
},
{
"id": "DS.d7.s2",
"text": [
"Thus, SR-BI influences neural and cognitive processes, a finding that highlights the contribution of cholesterol and alpha-tocopherol homeostasis in proper cognitive function."
],
"offsets": [
[
282,
457
]
],
"type": ""
}
] | [
{
"id": "DS.d7.s0.e1",
"type": "protein",
"text": [
"SR-BI"
],
"offsets": [
[
41,
46
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18824"
},
{
"db_name": "UniProt",
"db_id": "P97943"
},
{
"db_name": "UniProt",
"db_id": "Q60417"
},
{
"db_name": "UniProt",
"db_id": "Q61009"
},
{
"db_name": "UniProt",
"db_id": "Q8SQC1"
},
{
"db_name": "UniProt",
"db_id": "Q8WTV0"
}
]
},
{
"id": "DS.d7.s0.e2",
"type": "compound",
"text": [
"cholesterol"
],
"offsets": [
[
94,
105
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "304"
},
{
"db_name": "PubChem",
"db_id": "5997"
},
{
"db_name": "PubChem",
"db_id": "6432564"
},
{
"db_name": "PubChem",
"db_id": "11025495"
}
]
},
{
"id": "DS.d7.s0.e3",
"type": "compound",
"text": [
"alpha-tocopherol"
],
"offsets": [
[
110,
126
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2116"
},
{
"db_name": "PubChem",
"db_id": "14985"
}
]
},
{
"id": "DS.d7.s1.e0",
"type": "protein",
"text": [
"SR-BI"
],
"offsets": [
[
128,
133
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18824"
},
{
"db_name": "UniProt",
"db_id": "P97943"
},
{
"db_name": "UniProt",
"db_id": "Q60417"
},
{
"db_name": "UniProt",
"db_id": "Q61009"
},
{
"db_name": "UniProt",
"db_id": "Q8SQC1"
},
{
"db_name": "UniProt",
"db_id": "Q8WTV0"
}
]
},
{
"id": "DS.d7.s1.e1",
"type": "protein",
"text": [
"high-density lipoproteins"
],
"offsets": [
[
140,
165
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P81182"
}
]
},
{
"id": "DS.d7.s1.e2",
"type": "compound",
"text": [
"alpha-tocopherol"
],
"offsets": [
[
234,
250
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2116"
},
{
"db_name": "PubChem",
"db_id": "14985"
}
]
},
{
"id": "DS.d7.s2.e0",
"type": "protein",
"text": [
"SR-BI"
],
"offsets": [
[
288,
293
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18824"
},
{
"db_name": "UniProt",
"db_id": "P97943"
},
{
"db_name": "UniProt",
"db_id": "Q60417"
},
{
"db_name": "UniProt",
"db_id": "Q61009"
},
{
"db_name": "UniProt",
"db_id": "Q8SQC1"
},
{
"db_name": "UniProt",
"db_id": "Q8WTV0"
}
]
},
{
"id": "DS.d7.s2.e1",
"type": "compound",
"text": [
"cholesterol"
],
"offsets": [
[
383,
394
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "304"
},
{
"db_name": "PubChem",
"db_id": "5997"
},
{
"db_name": "PubChem",
"db_id": "6432564"
},
{
"db_name": "PubChem",
"db_id": "11025495"
}
]
},
{
"id": "DS.d7.s2.e2",
"type": "compound",
"text": [
"alpha-tocopherol"
],
"offsets": [
[
399,
415
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2116"
},
{
"db_name": "PubChem",
"db_id": "14985"
}
]
}
] | [] | [] | [
{
"id": "DS.d7.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d7.s0.e3",
"arg2_id": "DS.d7.s0.e1",
"normalized": []
},
{
"id": "DS.d7.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d7.s0.e2",
"arg2_id": "DS.d7.s0.e1",
"normalized": []
},
{
"id": "DS.d7.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d7.s1.e2",
"arg2_id": "DS.d7.s1.e0",
"normalized": []
}
] |
DS.d8 | 17768029 | [
{
"id": "DS.d8.s0",
"text": [
"Alloxan is believed to confer its diabetogenic effect by inhibiting pancreatic glucokinase activity, leading to pancreatic beta-cell death."
],
"offsets": [
[
0,
139
]
],
"type": ""
}
] | [
{
"id": "DS.d8.s0.e0",
"type": "compound",
"text": [
"Alloxan"
],
"offsets": [
[
0,
7
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5781"
}
]
},
{
"id": "DS.d8.s0.e1",
"type": "protein",
"text": [
"glucokinase"
],
"offsets": [
[
79,
90
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O25731"
},
{
"db_name": "UniProt",
"db_id": "P0A4E1"
},
{
"db_name": "UniProt",
"db_id": "P0A4E2"
},
{
"db_name": "UniProt",
"db_id": "P0A6V8"
},
{
"db_name": "UniProt",
"db_id": "P0A6V9"
},
{
"db_name": "UniProt",
"db_id": "P17712"
},
{
"db_name": "UniProt",
"db_id": "P21908"
},
{
"db_name": "UniProt",
"db_id": "P35557"
},
{
"db_name": "UniProt",
"db_id": "P52792"
},
{
"db_name": "UniProt",
"db_id": "P54495"
},
{
"db_name": "UniProt",
"db_id": "P58616"
},
{
"db_name": "UniProt",
"db_id": "P58617"
},
{
"db_name": "UniProt",
"db_id": "P58618"
},
{
"db_name": "UniProt",
"db_id": "P58619"
},
{
"db_name": "UniProt",
"db_id": "P64253"
},
{
"db_name": "UniProt",
"db_id": "P64254"
},
{
"db_name": "UniProt",
"db_id": "P82680"
},
{
"db_name": "UniProt",
"db_id": "Q55855"
},
{
"db_name": "UniProt",
"db_id": "Q56198"
},
{
"db_name": "UniProt",
"db_id": "Q59171"
},
{
"db_name": "UniProt",
"db_id": "Q668N7"
},
{
"db_name": "UniProt",
"db_id": "Q6D7C4"
},
{
"db_name": "UniProt",
"db_id": "Q7N6Y0"
},
{
"db_name": "UniProt",
"db_id": "Q83K86"
},
{
"db_name": "UniProt",
"db_id": "Q87EG6"
},
{
"db_name": "UniProt",
"db_id": "Q8FFD4"
},
{
"db_name": "UniProt",
"db_id": "Q8FV09"
},
{
"db_name": "UniProt",
"db_id": "Q8P8U7"
},
{
"db_name": "UniProt",
"db_id": "Q8PKU2"
},
{
"db_name": "UniProt",
"db_id": "Q8UIV7"
},
{
"db_name": "UniProt",
"db_id": "Q8YDC6"
},
{
"db_name": "UniProt",
"db_id": "Q92407"
},
{
"db_name": "UniProt",
"db_id": "Q92T27"
},
{
"db_name": "UniProt",
"db_id": "Q93IM5"
},
{
"db_name": "UniProt",
"db_id": "Q98DM2"
},
{
"db_name": "UniProt",
"db_id": "Q9A6N3"
},
{
"db_name": "UniProt",
"db_id": "Q9HZ46"
},
{
"db_name": "UniProt",
"db_id": "Q9KCZ4"
},
{
"db_name": "UniProt",
"db_id": "Q9PEG4"
},
{
"db_name": "UniProt",
"db_id": "Q9ZKB0"
}
]
}
] | [] | [] | [
{
"id": "DS.d8.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d8.s0.e0",
"arg2_id": "DS.d8.s0.e1",
"normalized": []
}
] |
DS.d9 | 17882129 | [
{
"id": "DS.d9.s0",
"text": [
"Alpha-tocopherol supplementation prevents the exercise-induced reduction of serum paraoxonase 1/arylesterase activities in healthy individuals."
],
"offsets": [
[
0,
143
]
],
"type": ""
}
] | [
{
"id": "DS.d9.s0.e0",
"type": "compound",
"text": [
"Alpha-tocopherol"
],
"offsets": [
[
0,
16
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2116"
},
{
"db_name": "PubChem",
"db_id": "14985"
}
]
},
{
"id": "DS.d9.s0.e1",
"type": "protein",
"text": [
"arylesterase"
],
"offsets": [
[
96,
108
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P22862"
}
]
}
] | [] | [] | [
{
"id": "DS.d9.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d9.s0.e0",
"arg2_id": "DS.d9.s0.e1",
"normalized": []
}
] |
DS.d10 | 17888544 | [
{
"id": "DS.d10.s0",
"text": [
"Although ApoE4 has been repeatedly associated with altered sphingomyelin and cholesterol levels in tissue culture and rodent models, there has not been a direct quantification of sphingomyelin or sterol levels in the brains of patients with different forms of ApoE."
],
"offsets": [
[
0,
265
]
],
"type": ""
}
] | [
{
"id": "DS.d10.s0.e0",
"type": "compound",
"text": [
"cholesterol"
],
"offsets": [
[
77,
88
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "304"
},
{
"db_name": "PubChem",
"db_id": "5997"
},
{
"db_name": "PubChem",
"db_id": "6432564"
},
{
"db_name": "PubChem",
"db_id": "11025495"
}
]
},
{
"id": "DS.d10.s0.e1",
"type": "protein",
"text": [
"ApoE"
],
"offsets": [
[
9,
13
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P02649"
},
{
"db_name": "UniProt",
"db_id": "P02650"
},
{
"db_name": "UniProt",
"db_id": "P05770"
},
{
"db_name": "UniProt",
"db_id": "P08226"
},
{
"db_name": "UniProt",
"db_id": "P10517"
},
{
"db_name": "UniProt",
"db_id": "P18287"
},
{
"db_name": "UniProt",
"db_id": "P18649"
},
{
"db_name": "UniProt",
"db_id": "P18650"
},
{
"db_name": "UniProt",
"db_id": "P23529"
},
{
"db_name": "UniProt",
"db_id": "Q03247"
},
{
"db_name": "UniProt",
"db_id": "Q28502"
},
{
"db_name": "UniProt",
"db_id": "Q28995"
},
{
"db_name": "UniProt",
"db_id": "Q7M2U7"
},
{
"db_name": "UniProt",
"db_id": "Q7M2U8"
},
{
"db_name": "UniProt",
"db_id": "Q9GJU3"
},
{
"db_name": "UniProt",
"db_id": "Q9GLC0"
},
{
"db_name": "UniProt",
"db_id": "Q9GLM6"
},
{
"db_name": "UniProt",
"db_id": "Q9GLM7"
},
{
"db_name": "UniProt",
"db_id": "Q9GLM8"
}
]
}
] | [] | [] | [
{
"id": "DS.d10.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d10.s0.e0",
"arg2_id": "DS.d10.s0.e1",
"normalized": []
}
] |
DS.d11 | 17888546 | [
{
"id": "DS.d11.s0",
"text": [
"ApoE modified the association between cholesterol and cognitive decline, and the association between the ratio of 27-hydroxycholesterol to cholesterol and cognitive functioning."
],
"offsets": [
[
0,
177
]
],
"type": ""
}
] | [
{
"id": "DS.d11.s0.e0",
"type": "protein",
"text": [
"ApoE"
],
"offsets": [
[
0,
4
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P02649"
},
{
"db_name": "UniProt",
"db_id": "P02650"
},
{
"db_name": "UniProt",
"db_id": "P05770"
},
{
"db_name": "UniProt",
"db_id": "P08226"
},
{
"db_name": "UniProt",
"db_id": "P10517"
},
{
"db_name": "UniProt",
"db_id": "P18287"
},
{
"db_name": "UniProt",
"db_id": "P18649"
},
{
"db_name": "UniProt",
"db_id": "P18650"
},
{
"db_name": "UniProt",
"db_id": "P23529"
},
{
"db_name": "UniProt",
"db_id": "Q03247"
},
{
"db_name": "UniProt",
"db_id": "Q28502"
},
{
"db_name": "UniProt",
"db_id": "Q28995"
},
{
"db_name": "UniProt",
"db_id": "Q7M2U7"
},
{
"db_name": "UniProt",
"db_id": "Q7M2U8"
},
{
"db_name": "UniProt",
"db_id": "Q9GJU3"
},
{
"db_name": "UniProt",
"db_id": "Q9GLC0"
},
{
"db_name": "UniProt",
"db_id": "Q9GLM6"
},
{
"db_name": "UniProt",
"db_id": "Q9GLM7"
},
{
"db_name": "UniProt",
"db_id": "Q9GLM8"
}
]
},
{
"id": "DS.d11.s0.e1",
"type": "compound",
"text": [
"cholesterol"
],
"offsets": [
[
38,
49
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "304"
},
{
"db_name": "PubChem",
"db_id": "5997"
},
{
"db_name": "PubChem",
"db_id": "6432564"
},
{
"db_name": "PubChem",
"db_id": "11025495"
}
]
},
{
"id": "DS.d11.s0.e2",
"type": "compound",
"text": [
"27-hydroxycholesterol"
],
"offsets": [
[
114,
135
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "99470"
},
{
"db_name": "PubChem",
"db_id": "123976"
},
{
"db_name": "PubChem",
"db_id": "50990021"
}
]
},
{
"id": "DS.d11.s0.e3",
"type": "compound",
"text": [
"cholesterol"
],
"offsets": [
[
124,
135
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "304"
},
{
"db_name": "PubChem",
"db_id": "5997"
},
{
"db_name": "PubChem",
"db_id": "6432564"
},
{
"db_name": "PubChem",
"db_id": "11025495"
}
]
}
] | [] | [] | [
{
"id": "DS.d11.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d11.s0.e2",
"arg2_id": "DS.d11.s0.e0",
"normalized": []
},
{
"id": "DS.d11.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d11.s0.e1",
"arg2_id": "DS.d11.s0.e0",
"normalized": []
}
] |
DS.d12 | 17890844 | [
{
"id": "DS.d12.s0",
"text": [
"Here we show that during growth in media containing glucose and in complex medium without glucose RamB activates expression of the aceE gene, encoding the E1p subunit of the pyruvate dehydrogenase complex."
],
"offsets": [
[
0,
205
]
],
"type": ""
}
] | [
{
"id": "DS.d12.s0.e0",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
52,
59
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d12.s0.e1",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
90,
97
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d12.s0.e2",
"type": "protein",
"text": [
"aceE"
],
"offsets": [
[
131,
135
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0AFG8"
},
{
"db_name": "UniProt",
"db_id": "P0AFG9"
},
{
"db_name": "UniProt",
"db_id": "P45119"
},
{
"db_name": "UniProt",
"db_id": "P57301"
},
{
"db_name": "UniProt",
"db_id": "Q10504"
},
{
"db_name": "UniProt",
"db_id": "Q59637"
},
{
"db_name": "UniProt",
"db_id": "Q89AR0"
},
{
"db_name": "UniProt",
"db_id": "Q8K9T9"
}
]
}
] | [] | [] | [] |
DS.d13 | 17925795 | [
{
"id": "DS.d13.s0",
"text": [
"The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons."
],
"offsets": [
[
0,
128
]
],
"type": ""
},
{
"id": "DS.d13.s1",
"text": [
"Treatment of cultured rat cortical neurons with therapeutic concentrations of LiCl or VPA selectively increased the levels of exon IV (formerly rat exon III)-containing BDNF mRNA, and the activity of BDNF promoter IV."
],
"offsets": [
[
129,
346
]
],
"type": ""
},
{
"id": "DS.d13.s2",
"text": [
"We showed that lithium-induced activation of promoter IV was mimicked by pharmacological inhibition of GSK-3 or short interfering RNA (siRNA)-mediated gene silencing of GSK-3alpha or GSK-3beta isoforms."
],
"offsets": [
[
347,
549
]
],
"type": ""
},
{
"id": "DS.d13.s3",
"text": [
"Furthermore, treatment with other HDAC inhibitors, sodium butyrate and trichostatin A, or transfection with an HDAC1-specific siRNA also activated BDNF promoter IV."
],
"offsets": [
[
550,
714
]
],
"type": ""
},
{
"id": "DS.d13.s4",
"text": [
"Our study demonstrates for the first time that GSK-3 and HDAC are respective initial targets for lithium and VPA to activate BDNF promoter IV, and that this BDNF induction involves a novel responsive region in promoter IV of the BDNF gene."
],
"offsets": [
[
715,
954
]
],
"type": ""
}
] | [
{
"id": "DS.d13.s0.e0",
"type": "compound",
"text": [
"lithium"
],
"offsets": [
[
21,
28
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "28486"
},
{
"db_name": "PubChem",
"db_id": "3028194"
}
]
},
{
"id": "DS.d13.s0.e1",
"type": "compound",
"text": [
"valproate"
],
"offsets": [
[
33,
42
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3121"
}
]
},
{
"id": "DS.d13.s0.e2",
"type": "protein",
"text": [
"brain-derived neurotrophic factor"
],
"offsets": [
[
83,
116
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P25430"
},
{
"db_name": "UniProt",
"db_id": "P25431"
},
{
"db_name": "UniProt",
"db_id": "P25432"
},
{
"db_name": "UniProt",
"db_id": "Q06225"
}
]
},
{
"id": "DS.d13.s1.e0",
"type": "compound",
"text": [
"LiCl"
],
"offsets": [
[
207,
211
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "433294"
}
]
},
{
"id": "DS.d13.s1.e1",
"type": "protein",
"text": [
"BDNF"
],
"offsets": [
[
298,
302
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18752"
},
{
"db_name": "UniProt",
"db_id": "O18753"
},
{
"db_name": "UniProt",
"db_id": "O18755"
},
{
"db_name": "UniProt",
"db_id": "O70183"
},
{
"db_name": "UniProt",
"db_id": "O97759"
},
{
"db_name": "UniProt",
"db_id": "P14082"
},
{
"db_name": "UniProt",
"db_id": "P21237"
},
{
"db_name": "UniProt",
"db_id": "P23363"
},
{
"db_name": "UniProt",
"db_id": "P23560"
},
{
"db_name": "UniProt",
"db_id": "P25429"
},
{
"db_name": "UniProt",
"db_id": "P25430"
},
{
"db_name": "UniProt",
"db_id": "P25431"
},
{
"db_name": "UniProt",
"db_id": "P25432"
},
{
"db_name": "UniProt",
"db_id": "Q02193"
},
{
"db_name": "UniProt",
"db_id": "Q06225"
},
{
"db_name": "UniProt",
"db_id": "Q3SAT7"
},
{
"db_name": "UniProt",
"db_id": "Q4L0Y3"
},
{
"db_name": "UniProt",
"db_id": "Q5IS78"
},
{
"db_name": "UniProt",
"db_id": "Q6LCI5"
},
{
"db_name": "UniProt",
"db_id": "Q7YRB4"
},
{
"db_name": "UniProt",
"db_id": "Q90322"
},
{
"db_name": "UniProt",
"db_id": "Q95106"
},
{
"db_name": "UniProt",
"db_id": "Q9TST3"
}
]
},
{
"id": "DS.d13.s1.e2",
"type": "protein",
"text": [
"BDNF"
],
"offsets": [
[
329,
333
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18752"
},
{
"db_name": "UniProt",
"db_id": "O18753"
},
{
"db_name": "UniProt",
"db_id": "O18755"
},
{
"db_name": "UniProt",
"db_id": "O70183"
},
{
"db_name": "UniProt",
"db_id": "O97759"
},
{
"db_name": "UniProt",
"db_id": "P14082"
},
{
"db_name": "UniProt",
"db_id": "P21237"
},
{
"db_name": "UniProt",
"db_id": "P23363"
},
{
"db_name": "UniProt",
"db_id": "P23560"
},
{
"db_name": "UniProt",
"db_id": "P25429"
},
{
"db_name": "UniProt",
"db_id": "P25430"
},
{
"db_name": "UniProt",
"db_id": "P25431"
},
{
"db_name": "UniProt",
"db_id": "P25432"
},
{
"db_name": "UniProt",
"db_id": "Q02193"
},
{
"db_name": "UniProt",
"db_id": "Q06225"
},
{
"db_name": "UniProt",
"db_id": "Q3SAT7"
},
{
"db_name": "UniProt",
"db_id": "Q4L0Y3"
},
{
"db_name": "UniProt",
"db_id": "Q5IS78"
},
{
"db_name": "UniProt",
"db_id": "Q6LCI5"
},
{
"db_name": "UniProt",
"db_id": "Q7YRB4"
},
{
"db_name": "UniProt",
"db_id": "Q90322"
},
{
"db_name": "UniProt",
"db_id": "Q95106"
},
{
"db_name": "UniProt",
"db_id": "Q9TST3"
}
]
},
{
"id": "DS.d13.s2.e0",
"type": "compound",
"text": [
"lithium"
],
"offsets": [
[
362,
369
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "28486"
},
{
"db_name": "PubChem",
"db_id": "3028194"
}
]
},
{
"id": "DS.d13.s2.e1",
"type": "protein",
"text": [
"GSK-3"
],
"offsets": [
[
450,
455
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P51136"
},
{
"db_name": "UniProt",
"db_id": "P83101"
}
]
},
{
"id": "DS.d13.s2.e2",
"type": "protein",
"text": [
"GSK-3alpha"
],
"offsets": [
[
516,
526
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P18265"
},
{
"db_name": "UniProt",
"db_id": "P49840"
}
]
},
{
"id": "DS.d13.s2.e3",
"type": "protein",
"text": [
"GSK-3beta"
],
"offsets": [
[
530,
539
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P18266"
},
{
"db_name": "UniProt",
"db_id": "P49841"
},
{
"db_name": "UniProt",
"db_id": "Q5YJC2"
},
{
"db_name": "UniProt",
"db_id": "Q9WV60"
}
]
},
{
"id": "DS.d13.s3.e0",
"type": "compound",
"text": [
"sodium butyrate"
],
"offsets": [
[
601,
616
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "264"
}
]
},
{
"id": "DS.d13.s3.e1",
"type": "compound",
"text": [
"trichostatin A"
],
"offsets": [
[
621,
635
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "444732"
}
]
},
{
"id": "DS.d13.s3.e2",
"type": "protein",
"text": [
"BDNF"
],
"offsets": [
[
697,
701
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18752"
},
{
"db_name": "UniProt",
"db_id": "O18753"
},
{
"db_name": "UniProt",
"db_id": "O18755"
},
{
"db_name": "UniProt",
"db_id": "O70183"
},
{
"db_name": "UniProt",
"db_id": "O97759"
},
{
"db_name": "UniProt",
"db_id": "P14082"
},
{
"db_name": "UniProt",
"db_id": "P21237"
},
{
"db_name": "UniProt",
"db_id": "P23363"
},
{
"db_name": "UniProt",
"db_id": "P23560"
},
{
"db_name": "UniProt",
"db_id": "P25429"
},
{
"db_name": "UniProt",
"db_id": "P25430"
},
{
"db_name": "UniProt",
"db_id": "P25431"
},
{
"db_name": "UniProt",
"db_id": "P25432"
},
{
"db_name": "UniProt",
"db_id": "Q02193"
},
{
"db_name": "UniProt",
"db_id": "Q06225"
},
{
"db_name": "UniProt",
"db_id": "Q3SAT7"
},
{
"db_name": "UniProt",
"db_id": "Q4L0Y3"
},
{
"db_name": "UniProt",
"db_id": "Q5IS78"
},
{
"db_name": "UniProt",
"db_id": "Q6LCI5"
},
{
"db_name": "UniProt",
"db_id": "Q7YRB4"
},
{
"db_name": "UniProt",
"db_id": "Q90322"
},
{
"db_name": "UniProt",
"db_id": "Q95106"
},
{
"db_name": "UniProt",
"db_id": "Q9TST3"
}
]
},
{
"id": "DS.d13.s4.e0",
"type": "protein",
"text": [
"GSK-3"
],
"offsets": [
[
762,
767
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P51136"
},
{
"db_name": "UniProt",
"db_id": "P83101"
}
]
},
{
"id": "DS.d13.s4.e1",
"type": "compound",
"text": [
"lithium"
],
"offsets": [
[
812,
819
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "28486"
},
{
"db_name": "PubChem",
"db_id": "3028194"
}
]
},
{
"id": "DS.d13.s4.e2",
"type": "protein",
"text": [
"BDNF"
],
"offsets": [
[
840,
844
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18752"
},
{
"db_name": "UniProt",
"db_id": "O18753"
},
{
"db_name": "UniProt",
"db_id": "O18755"
},
{
"db_name": "UniProt",
"db_id": "O70183"
},
{
"db_name": "UniProt",
"db_id": "O97759"
},
{
"db_name": "UniProt",
"db_id": "P14082"
},
{
"db_name": "UniProt",
"db_id": "P21237"
},
{
"db_name": "UniProt",
"db_id": "P23363"
},
{
"db_name": "UniProt",
"db_id": "P23560"
},
{
"db_name": "UniProt",
"db_id": "P25429"
},
{
"db_name": "UniProt",
"db_id": "P25430"
},
{
"db_name": "UniProt",
"db_id": "P25431"
},
{
"db_name": "UniProt",
"db_id": "P25432"
},
{
"db_name": "UniProt",
"db_id": "Q02193"
},
{
"db_name": "UniProt",
"db_id": "Q06225"
},
{
"db_name": "UniProt",
"db_id": "Q3SAT7"
},
{
"db_name": "UniProt",
"db_id": "Q4L0Y3"
},
{
"db_name": "UniProt",
"db_id": "Q5IS78"
},
{
"db_name": "UniProt",
"db_id": "Q6LCI5"
},
{
"db_name": "UniProt",
"db_id": "Q7YRB4"
},
{
"db_name": "UniProt",
"db_id": "Q90322"
},
{
"db_name": "UniProt",
"db_id": "Q95106"
},
{
"db_name": "UniProt",
"db_id": "Q9TST3"
}
]
},
{
"id": "DS.d13.s4.e3",
"type": "protein",
"text": [
"BDNF"
],
"offsets": [
[
872,
876
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18752"
},
{
"db_name": "UniProt",
"db_id": "O18753"
},
{
"db_name": "UniProt",
"db_id": "O18755"
},
{
"db_name": "UniProt",
"db_id": "O70183"
},
{
"db_name": "UniProt",
"db_id": "O97759"
},
{
"db_name": "UniProt",
"db_id": "P14082"
},
{
"db_name": "UniProt",
"db_id": "P21237"
},
{
"db_name": "UniProt",
"db_id": "P23363"
},
{
"db_name": "UniProt",
"db_id": "P23560"
},
{
"db_name": "UniProt",
"db_id": "P25429"
},
{
"db_name": "UniProt",
"db_id": "P25430"
},
{
"db_name": "UniProt",
"db_id": "P25431"
},
{
"db_name": "UniProt",
"db_id": "P25432"
},
{
"db_name": "UniProt",
"db_id": "Q02193"
},
{
"db_name": "UniProt",
"db_id": "Q06225"
},
{
"db_name": "UniProt",
"db_id": "Q3SAT7"
},
{
"db_name": "UniProt",
"db_id": "Q4L0Y3"
},
{
"db_name": "UniProt",
"db_id": "Q5IS78"
},
{
"db_name": "UniProt",
"db_id": "Q6LCI5"
},
{
"db_name": "UniProt",
"db_id": "Q7YRB4"
},
{
"db_name": "UniProt",
"db_id": "Q90322"
},
{
"db_name": "UniProt",
"db_id": "Q95106"
},
{
"db_name": "UniProt",
"db_id": "Q9TST3"
}
]
},
{
"id": "DS.d13.s4.e4",
"type": "protein",
"text": [
"BDNF"
],
"offsets": [
[
872,
876
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18752"
},
{
"db_name": "UniProt",
"db_id": "O18753"
},
{
"db_name": "UniProt",
"db_id": "O18755"
},
{
"db_name": "UniProt",
"db_id": "O70183"
},
{
"db_name": "UniProt",
"db_id": "O97759"
},
{
"db_name": "UniProt",
"db_id": "P14082"
},
{
"db_name": "UniProt",
"db_id": "P21237"
},
{
"db_name": "UniProt",
"db_id": "P23363"
},
{
"db_name": "UniProt",
"db_id": "P23560"
},
{
"db_name": "UniProt",
"db_id": "P25429"
},
{
"db_name": "UniProt",
"db_id": "P25430"
},
{
"db_name": "UniProt",
"db_id": "P25431"
},
{
"db_name": "UniProt",
"db_id": "P25432"
},
{
"db_name": "UniProt",
"db_id": "Q02193"
},
{
"db_name": "UniProt",
"db_id": "Q06225"
},
{
"db_name": "UniProt",
"db_id": "Q3SAT7"
},
{
"db_name": "UniProt",
"db_id": "Q4L0Y3"
},
{
"db_name": "UniProt",
"db_id": "Q5IS78"
},
{
"db_name": "UniProt",
"db_id": "Q6LCI5"
},
{
"db_name": "UniProt",
"db_id": "Q7YRB4"
},
{
"db_name": "UniProt",
"db_id": "Q90322"
},
{
"db_name": "UniProt",
"db_id": "Q95106"
},
{
"db_name": "UniProt",
"db_id": "Q9TST3"
}
]
}
] | [] | [] | [
{
"id": "DS.d13.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s0.e0",
"arg2_id": "DS.d13.s0.e2",
"normalized": []
},
{
"id": "DS.d13.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s0.e1",
"arg2_id": "DS.d13.s0.e2",
"normalized": []
},
{
"id": "DS.d13.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s1.e0",
"arg2_id": "DS.d13.s1.e1",
"normalized": []
},
{
"id": "DS.d13.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s2.e0",
"arg2_id": "DS.d13.s2.e2",
"normalized": []
},
{
"id": "DS.d13.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s2.e0",
"arg2_id": "DS.d13.s2.e3",
"normalized": []
},
{
"id": "DS.d13.s2.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s2.e0",
"arg2_id": "DS.d13.s2.e1",
"normalized": []
},
{
"id": "DS.d13.s3.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s3.e0",
"arg2_id": "DS.d13.s3.e2",
"normalized": []
},
{
"id": "DS.d13.s3.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s3.e1",
"arg2_id": "DS.d13.s3.e2",
"normalized": []
},
{
"id": "DS.d13.s4.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d13.s4.e1",
"arg2_id": "DS.d13.s4.e0",
"normalized": []
}
] |
DS.d14 | 17941873 | [
{
"id": "DS.d14.s0",
"text": [
"Addition of biphasic insulin aspart 30 to optimized metformin and pioglitazone treatment of type 2 diabetes mellitus: The ACTION Study (Achieving Control Through Insulin plus Oral ageNts)."
],
"offsets": [
[
0,
188
]
],
"type": ""
},
{
"id": "DS.d14.s1",
"text": [
"Efficacy and safety of biphasic insulin aspart (BIAsp 30, 30% short-acting and 70% intermediate-acting insulin aspart) added to an optimized treatment of metformin and pioglitazone (met/pio) were compared with treatment with optimized met/pio in type 2 diabetes patients."
],
"offsets": [
[
189,
460
]
],
"type": ""
}
] | [
{
"id": "DS.d14.s0.e0",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
21,
28
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d14.s0.e1",
"type": "compound",
"text": [
"metformin"
],
"offsets": [
[
52,
61
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4091"
}
]
},
{
"id": "DS.d14.s0.e2",
"type": "compound",
"text": [
"pioglitazone"
],
"offsets": [
[
66,
78
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4829"
}
]
},
{
"id": "DS.d14.s0.e3",
"type": "protein",
"text": [
"Insulin"
],
"offsets": [
[
162,
169
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d14.s1.e0",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
221,
228
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d14.s1.e1",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
292,
299
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d14.s1.e2",
"type": "compound",
"text": [
"metformin"
],
"offsets": [
[
343,
352
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4091"
}
]
},
{
"id": "DS.d14.s1.e3",
"type": "compound",
"text": [
"pioglitazone"
],
"offsets": [
[
357,
369
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4829"
}
]
}
] | [] | [] | [] |
DS.d15 | 17943458 | [
{
"id": "DS.d15.s0",
"text": [
"N-acetylaspartic acid (NAA) is converted into aspartate and acetate by aspartoacylase."
],
"offsets": [
[
0,
86
]
],
"type": ""
}
] | [
{
"id": "DS.d15.s0.e0",
"type": "compound",
"text": [
"N-acetylaspartic acid"
],
"offsets": [
[
0,
21
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "65065"
}
]
},
{
"id": "DS.d15.s0.e1",
"type": "compound",
"text": [
"aspartate"
],
"offsets": [
[
46,
55
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5960"
}
]
},
{
"id": "DS.d15.s0.e2",
"type": "compound",
"text": [
"acetate"
],
"offsets": [
[
60,
67
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "53627460"
}
]
},
{
"id": "DS.d15.s0.e3",
"type": "protein",
"text": [
"aspartoacylase"
],
"offsets": [
[
71,
85
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P45381"
},
{
"db_name": "UniProt",
"db_id": "P46446"
},
{
"db_name": "UniProt",
"db_id": "Q60HH2"
},
{
"db_name": "UniProt",
"db_id": "Q8R3P0"
},
{
"db_name": "UniProt",
"db_id": "Q9R1T5"
}
]
}
] | [] | [] | [
{
"id": "DS.d15.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d15.s0.e0",
"arg2_id": "DS.d15.s0.e3",
"normalized": []
},
{
"id": "DS.d15.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d15.s0.e1",
"arg2_id": "DS.d15.s0.e3",
"normalized": []
},
{
"id": "DS.d15.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d15.s0.e2",
"arg2_id": "DS.d15.s0.e3",
"normalized": []
}
] |
DS.d16 | 17950491 | [
{
"id": "DS.d16.s0",
"text": [
"In addition, treatment with rosiglitazone increased interleukin-4 (IL-4) mRNA and reversed the age-related decrease in hippocampal IL-4 concentration."
],
"offsets": [
[
0,
150
]
],
"type": ""
}
] | [
{
"id": "DS.d16.s0.e0",
"type": "compound",
"text": [
"rosiglitazone"
],
"offsets": [
[
28,
41
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "77999"
}
]
},
{
"id": "DS.d16.s0.e1",
"type": "protein",
"text": [
"IL-4"
],
"offsets": [
[
67,
71
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O77762"
},
{
"db_name": "UniProt",
"db_id": "P05112"
},
{
"db_name": "UniProt",
"db_id": "P07750"
},
{
"db_name": "UniProt",
"db_id": "P20096"
},
{
"db_name": "UniProt",
"db_id": "P30367"
},
{
"db_name": "UniProt",
"db_id": "P30368"
},
{
"db_name": "UniProt",
"db_id": "P42202"
},
{
"db_name": "UniProt",
"db_id": "P46652"
},
{
"db_name": "UniProt",
"db_id": "P47966"
},
{
"db_name": "UniProt",
"db_id": "P51492"
},
{
"db_name": "UniProt",
"db_id": "P51744"
},
{
"db_name": "UniProt",
"db_id": "P55030"
},
{
"db_name": "UniProt",
"db_id": "P79155"
},
{
"db_name": "UniProt",
"db_id": "P79339"
},
{
"db_name": "UniProt",
"db_id": "Q04745"
},
{
"db_name": "UniProt",
"db_id": "Q2PE74"
},
{
"db_name": "UniProt",
"db_id": "Q3S4V6"
},
{
"db_name": "UniProt",
"db_id": "Q58M18"
},
{
"db_name": "UniProt",
"db_id": "Q60440"
},
{
"db_name": "UniProt",
"db_id": "Q7YS71"
},
{
"db_name": "UniProt",
"db_id": "Q865X5"
},
{
"db_name": "UniProt",
"db_id": "Q865Y0"
},
{
"db_name": "UniProt",
"db_id": "Q8HYB1"
},
{
"db_name": "UniProt",
"db_id": "Q9MZR8"
},
{
"db_name": "UniProt",
"db_id": "Q9XS58"
}
]
},
{
"id": "DS.d16.s0.e2",
"type": "protein",
"text": [
"IL-4"
],
"offsets": [
[
131,
135
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O77762"
},
{
"db_name": "UniProt",
"db_id": "P05112"
},
{
"db_name": "UniProt",
"db_id": "P07750"
},
{
"db_name": "UniProt",
"db_id": "P20096"
},
{
"db_name": "UniProt",
"db_id": "P30367"
},
{
"db_name": "UniProt",
"db_id": "P30368"
},
{
"db_name": "UniProt",
"db_id": "P42202"
},
{
"db_name": "UniProt",
"db_id": "P46652"
},
{
"db_name": "UniProt",
"db_id": "P47966"
},
{
"db_name": "UniProt",
"db_id": "P51492"
},
{
"db_name": "UniProt",
"db_id": "P51744"
},
{
"db_name": "UniProt",
"db_id": "P55030"
},
{
"db_name": "UniProt",
"db_id": "P79155"
},
{
"db_name": "UniProt",
"db_id": "P79339"
},
{
"db_name": "UniProt",
"db_id": "Q04745"
},
{
"db_name": "UniProt",
"db_id": "Q2PE74"
},
{
"db_name": "UniProt",
"db_id": "Q3S4V6"
},
{
"db_name": "UniProt",
"db_id": "Q58M18"
},
{
"db_name": "UniProt",
"db_id": "Q60440"
},
{
"db_name": "UniProt",
"db_id": "Q7YS71"
},
{
"db_name": "UniProt",
"db_id": "Q865X5"
},
{
"db_name": "UniProt",
"db_id": "Q865Y0"
},
{
"db_name": "UniProt",
"db_id": "Q8HYB1"
},
{
"db_name": "UniProt",
"db_id": "Q9MZR8"
},
{
"db_name": "UniProt",
"db_id": "Q9XS58"
}
]
}
] | [] | [] | [
{
"id": "DS.d16.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d16.s0.e0",
"arg2_id": "DS.d16.s0.e1",
"normalized": []
}
] |
DS.d17 | 17965987 | [
{
"id": "DS.d17.s0",
"text": [
"Serum BDNF levels were increased and plasma levels of HVA and MHPG were decreased according to the recovery from the active phase of the disease."
],
"offsets": [
[
0,
145
]
],
"type": ""
},
{
"id": "DS.d17.s1",
"text": [
"These results suggest that dysfunctions of catecholaminergic neurons and neurotrophic factors might exist in Sydenham's chorea, and the decreasing catecholamine activities in response to risperidone might be associated with the improvement of the disease."
],
"offsets": [
[
146,
401
]
],
"type": ""
}
] | [
{
"id": "DS.d17.s0.e0",
"type": "protein",
"text": [
"BDNF"
],
"offsets": [
[
6,
10
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18752"
},
{
"db_name": "UniProt",
"db_id": "O18753"
},
{
"db_name": "UniProt",
"db_id": "O18755"
},
{
"db_name": "UniProt",
"db_id": "O70183"
},
{
"db_name": "UniProt",
"db_id": "O97759"
},
{
"db_name": "UniProt",
"db_id": "P14082"
},
{
"db_name": "UniProt",
"db_id": "P21237"
},
{
"db_name": "UniProt",
"db_id": "P23363"
},
{
"db_name": "UniProt",
"db_id": "P23560"
},
{
"db_name": "UniProt",
"db_id": "P25429"
},
{
"db_name": "UniProt",
"db_id": "P25430"
},
{
"db_name": "UniProt",
"db_id": "P25431"
},
{
"db_name": "UniProt",
"db_id": "P25432"
},
{
"db_name": "UniProt",
"db_id": "Q02193"
},
{
"db_name": "UniProt",
"db_id": "Q06225"
},
{
"db_name": "UniProt",
"db_id": "Q3SAT7"
},
{
"db_name": "UniProt",
"db_id": "Q4L0Y3"
},
{
"db_name": "UniProt",
"db_id": "Q5IS78"
},
{
"db_name": "UniProt",
"db_id": "Q6LCI5"
},
{
"db_name": "UniProt",
"db_id": "Q7YRB4"
},
{
"db_name": "UniProt",
"db_id": "Q90322"
},
{
"db_name": "UniProt",
"db_id": "Q95106"
},
{
"db_name": "UniProt",
"db_id": "Q9TST3"
}
]
},
{
"id": "DS.d17.s0.e1",
"type": "compound",
"text": [
"HVA"
],
"offsets": [
[
54,
57
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1738"
}
]
},
{
"id": "DS.d17.s0.e2",
"type": "compound",
"text": [
"MHPG"
],
"offsets": [
[
62,
66
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "10805"
}
]
},
{
"id": "DS.d17.s1.e0",
"type": "protein",
"text": [
"neurotrophic factors"
],
"offsets": [
[
219,
239
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P18280"
},
{
"db_name": "UniProt",
"db_id": "P20181"
},
{
"db_name": "UniProt",
"db_id": "P20783"
},
{
"db_name": "UniProt",
"db_id": "P25433"
},
{
"db_name": "UniProt",
"db_id": "P25434"
},
{
"db_name": "UniProt",
"db_id": "P25435"
},
{
"db_name": "UniProt",
"db_id": "Q9TST2"
}
]
},
{
"id": "DS.d17.s1.e1",
"type": "compound",
"text": [
"risperidone"
],
"offsets": [
[
333,
344
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5073"
}
]
}
] | [] | [] | [] |
DS.d18 | 17968352 | [
{
"id": "DS.d18.s0",
"text": [
"Based on these validities we identified alterations in the Wolframin gene in the CA1 and amygdala regions, specifically in exposed PTSD-like rats, which were normalized after treatment with citalopram."
],
"offsets": [
[
0,
201
]
],
"type": ""
}
] | [
{
"id": "DS.d18.s0.e0",
"type": "protein",
"text": [
"Wolframin"
],
"offsets": [
[
59,
68
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O76024"
},
{
"db_name": "UniProt",
"db_id": "P56695"
}
]
},
{
"id": "DS.d18.s0.e1",
"type": "compound",
"text": [
"citalopram"
],
"offsets": [
[
190,
200
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2771"
},
{
"db_name": "PubChem",
"db_id": "146570"
}
]
}
] | [] | [] | [
{
"id": "DS.d18.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d18.s0.e1",
"arg2_id": "DS.d18.s0.e0",
"normalized": []
}
] |
DS.d19 | 17968676 | [
{
"id": "DS.d19.s0",
"text": [
"Cyclooxygenase-2 (Cox-2) is a key enzyme in the conversion of arachidonic acid to prostaglandins that has been shown to have a particular importance in the progression of several malignancies including nasopharyngeal carcinoma (NPC)."
],
"offsets": [
[
0,
233
]
],
"type": ""
}
] | [
{
"id": "DS.d19.s0.e0",
"type": "protein",
"text": [
"Cyclooxygenase-2"
],
"offsets": [
[
0,
16
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O02768"
},
{
"db_name": "UniProt",
"db_id": "O19183"
},
{
"db_name": "UniProt",
"db_id": "O62698"
},
{
"db_name": "UniProt",
"db_id": "O62725"
},
{
"db_name": "UniProt",
"db_id": "P27607"
},
{
"db_name": "UniProt",
"db_id": "P35354"
},
{
"db_name": "UniProt",
"db_id": "P35355"
},
{
"db_name": "UniProt",
"db_id": "P70682"
},
{
"db_name": "UniProt",
"db_id": "P79208"
},
{
"db_name": "UniProt",
"db_id": "Q05769"
}
]
},
{
"id": "DS.d19.s0.e1",
"type": "protein",
"text": [
"Cox-2"
],
"offsets": [
[
18,
23
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P00411"
},
{
"db_name": "UniProt",
"db_id": "P24894"
},
{
"db_name": "UniProt",
"db_id": "P35355"
},
{
"db_name": "UniProt",
"db_id": "Q05769"
},
{
"db_name": "UniProt",
"db_id": "Q8HEC3"
},
{
"db_name": "UniProt",
"db_id": "Q8SEM9"
}
]
},
{
"id": "DS.d19.s0.e2",
"type": "compound",
"text": [
"arachidonic acid"
],
"offsets": [
[
62,
78
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "444899"
}
]
}
] | [] | [] | [
{
"id": "DS.d19.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d19.s0.e2",
"arg2_id": "DS.d19.s0.e0",
"normalized": []
},
{
"id": "DS.d19.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d19.s0.e2",
"arg2_id": "DS.d19.s0.e1",
"normalized": []
}
] |
DS.d20 | 17976762 | [
{
"id": "DS.d20.s0",
"text": [
"Other potential treatments discussed for possible use with long-acting insulin overdoses include incision and drainage of the injection site, glucagon, and octreotide."
],
"offsets": [
[
0,
167
]
],
"type": ""
}
] | [
{
"id": "DS.d20.s0.e0",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
71,
78
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
},
{
"id": "DS.d20.s0.e2",
"type": "compound",
"text": [
"octreotide"
],
"offsets": [
[
156,
166
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "383414"
},
{
"db_name": "PubChem",
"db_id": "448601"
}
]
}
] | [] | [] | [] |
DS.d21 | 18037312 | [
{
"id": "DS.d21.s0",
"text": [
"Cadmium inhalation induced: (1) a transient bronchial inflammation, dominated by neutrophils; (2) a neutrophilia of the blood that persisted for up to 4 weeks; (3) a transient increased bronchial reactivity, and (4) a significant increase in MMP-9 activity in the BALF."
],
"offsets": [
[
0,
269
]
],
"type": ""
}
] | [
{
"id": "DS.d21.s0.e0",
"type": "compound",
"text": [
"Cadmium"
],
"offsets": [
[
0,
7
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "23973"
}
]
},
{
"id": "DS.d21.s0.e1",
"type": "protein",
"text": [
"MMP-9"
],
"offsets": [
[
242,
247
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18733"
},
{
"db_name": "UniProt",
"db_id": "P14780"
},
{
"db_name": "UniProt",
"db_id": "P41245"
},
{
"db_name": "UniProt",
"db_id": "P41246"
},
{
"db_name": "UniProt",
"db_id": "P50282"
},
{
"db_name": "UniProt",
"db_id": "P52176"
}
]
}
] | [] | [] | [
{
"id": "DS.d21.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d21.s0.e0",
"arg2_id": "DS.d21.s0.e1",
"normalized": []
}
] |
DS.d22 | 18042181 | [
{
"id": "DS.d22.s0",
"text": [
"To assess whether follicle-stimulating hormone (FSH) and basic fibroblast growth factor (bFGF) modulate GSH production in Sertoli cells by regulating the expression of GCLC, GCLM and/or GR, we performed in vitro studies using rat Sertoli cells in primary culture."
],
"offsets": [
[
0,
263
]
],
"type": ""
},
{
"id": "DS.d22.s1",
"text": [
"In conclusion, our results show that FSH and bFGF increase GSH levels in Sertoli cells through stimulation of the de novo synthesis and recycling by upregulating GCLM and GR expression respectively."
],
"offsets": [
[
264,
462
]
],
"type": ""
}
] | [
{
"id": "DS.d22.s0.e0",
"type": "protein",
"text": [
"basic fibroblast growth factor"
],
"offsets": [
[
57,
87
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P03969"
},
{
"db_name": "UniProt",
"db_id": "P09038"
},
{
"db_name": "UniProt",
"db_id": "P12226"
},
{
"db_name": "UniProt",
"db_id": "P13109"
},
{
"db_name": "UniProt",
"db_id": "P15655"
},
{
"db_name": "UniProt",
"db_id": "P20003"
},
{
"db_name": "UniProt",
"db_id": "P48798"
},
{
"db_name": "UniProt",
"db_id": "P48799"
},
{
"db_name": "UniProt",
"db_id": "P48800"
},
{
"db_name": "UniProt",
"db_id": "Q60487"
}
]
},
{
"id": "DS.d22.s0.e1",
"type": "compound",
"text": [
"GSH"
],
"offsets": [
[
104,
107
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
},
{
"id": "DS.d22.s0.e2",
"type": "protein",
"text": [
"GCLC"
],
"offsets": [
[
168,
172
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P48506"
}
]
},
{
"id": "DS.d22.s0.e3",
"type": "protein",
"text": [
"GCLM"
],
"offsets": [
[
174,
178
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P48507"
},
{
"db_name": "UniProt",
"db_id": "Q2T9Y6"
}
]
},
{
"id": "DS.d22.s1.e0",
"type": "compound",
"text": [
"GSH"
],
"offsets": [
[
323,
326
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
},
{
"id": "DS.d22.s1.e1",
"type": "protein",
"text": [
"GCLM"
],
"offsets": [
[
426,
430
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P48507"
},
{
"db_name": "UniProt",
"db_id": "Q2T9Y6"
}
]
}
] | [] | [] | [] |
DS.d23 | 18061671 | [
{
"id": "DS.d23.s0",
"text": [
"Compared to the control, both the stresses individually and in combination led to in reductions in growth, photosynthetic pigments, ascorbic acid, catalase (CAT) activity and yield, whereas a reverse trend was observed for flavonoids, thiols and proline contents, superoxide dismutase (SOD) and peroxidase (POD) activities, and LPO."
],
"offsets": [
[
0,
332
]
],
"type": ""
}
] | [
{
"id": "DS.d23.s0.e0",
"type": "compound",
"text": [
"ascorbic acid"
],
"offsets": [
[
132,
145
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "54670067"
},
{
"db_name": "PubChem",
"db_id": "54690394"
}
]
},
{
"id": "DS.d23.s0.e1",
"type": "protein",
"text": [
"catalase"
],
"offsets": [
[
147,
155
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O24339"
},
{
"db_name": "UniProt",
"db_id": "O52762"
},
{
"db_name": "UniProt",
"db_id": "O62839"
},
{
"db_name": "UniProt",
"db_id": "O68146"
},
{
"db_name": "UniProt",
"db_id": "O77229"
},
{
"db_name": "UniProt",
"db_id": "O93662"
},
{
"db_name": "UniProt",
"db_id": "O97492"
},
{
"db_name": "UniProt",
"db_id": "P00432"
},
{
"db_name": "UniProt",
"db_id": "P04040"
},
{
"db_name": "UniProt",
"db_id": "P04762"
},
{
"db_name": "UniProt",
"db_id": "P07145"
},
{
"db_name": "UniProt",
"db_id": "P0A323"
},
{
"db_name": "UniProt",
"db_id": "P0A324"
},
{
"db_name": "UniProt",
"db_id": "P0A325"
},
{
"db_name": "UniProt",
"db_id": "P0A326"
},
{
"db_name": "UniProt",
"db_id": "P0A327"
},
{
"db_name": "UniProt",
"db_id": "P11934"
},
{
"db_name": "UniProt",
"db_id": "P17336"
},
{
"db_name": "UniProt",
"db_id": "P24168"
},
{
"db_name": "UniProt",
"db_id": "P24270"
},
{
"db_name": "UniProt",
"db_id": "P25890"
},
{
"db_name": "UniProt",
"db_id": "P29422"
},
{
"db_name": "UniProt",
"db_id": "P30265"
},
{
"db_name": "UniProt",
"db_id": "P30266"
},
{
"db_name": "UniProt",
"db_id": "P32290"
},
{
"db_name": "UniProt",
"db_id": "P42321"
},
{
"db_name": "UniProt",
"db_id": "P44390"
},
{
"db_name": "UniProt",
"db_id": "P45737"
},
{
"db_name": "UniProt",
"db_id": "P45739"
},
{
"db_name": "UniProt",
"db_id": "P55304"
},
{
"db_name": "UniProt",
"db_id": "P55306"
},
{
"db_name": "UniProt",
"db_id": "P55310"
},
{
"db_name": "UniProt",
"db_id": "P55311"
},
{
"db_name": "UniProt",
"db_id": "P55313"
},
{
"db_name": "UniProt",
"db_id": "P77872"
},
{
"db_name": "UniProt",
"db_id": "P81138"
},
{
"db_name": "UniProt",
"db_id": "P90682"
},
{
"db_name": "UniProt",
"db_id": "Q27710"
},
{
"db_name": "UniProt",
"db_id": "Q49XC1"
},
{
"db_name": "UniProt",
"db_id": "Q4L643"
},
{
"db_name": "UniProt",
"db_id": "Q59296"
},
{
"db_name": "UniProt",
"db_id": "Q59337"
},
{
"db_name": "UniProt",
"db_id": "Q59602"
},
{
"db_name": "UniProt",
"db_id": "Q59714"
},
{
"db_name": "UniProt",
"db_id": "Q5HG86"
},
{
"db_name": "UniProt",
"db_id": "Q5HPK8"
},
{
"db_name": "UniProt",
"db_id": "Q5RF10"
},
{
"db_name": "UniProt",
"db_id": "Q64405"
},
{
"db_name": "UniProt",
"db_id": "Q6G9M4"
},
{
"db_name": "UniProt",
"db_id": "Q6GH72"
},
{
"db_name": "UniProt",
"db_id": "Q7A5T2"
},
{
"db_name": "UniProt",
"db_id": "Q8CPD0"
},
{
"db_name": "UniProt",
"db_id": "Q8FWU0"
},
{
"db_name": "UniProt",
"db_id": "Q8NWV5"
},
{
"db_name": "UniProt",
"db_id": "Q8X1P0"
},
{
"db_name": "UniProt",
"db_id": "Q8Y3P9"
},
{
"db_name": "UniProt",
"db_id": "Q926X0"
},
{
"db_name": "UniProt",
"db_id": "Q99UE2"
},
{
"db_name": "UniProt",
"db_id": "Q9AXH0"
},
{
"db_name": "UniProt",
"db_id": "Q9KW19"
},
{
"db_name": "UniProt",
"db_id": "Q9L4S1"
},
{
"db_name": "UniProt",
"db_id": "Q9M5L6"
},
{
"db_name": "UniProt",
"db_id": "Q9PT92"
},
{
"db_name": "UniProt",
"db_id": "Q9PWF7"
},
{
"db_name": "UniProt",
"db_id": "Q9Z598"
},
{
"db_name": "UniProt",
"db_id": "Q9ZKX5"
},
{
"db_name": "UniProt",
"db_id": "Q9ZN99"
}
]
},
{
"id": "DS.d23.s0.e2",
"type": "protein",
"text": [
"CAT"
],
"offsets": [
[
157,
160
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62839"
},
{
"db_name": "UniProt",
"db_id": "O97492"
},
{
"db_name": "UniProt",
"db_id": "P00432"
},
{
"db_name": "UniProt",
"db_id": "P00485"
},
{
"db_name": "UniProt",
"db_id": "P00486"
},
{
"db_name": "UniProt",
"db_id": "P00487"
},
{
"db_name": "UniProt",
"db_id": "P04040"
},
{
"db_name": "UniProt",
"db_id": "P06135"
},
{
"db_name": "UniProt",
"db_id": "P07641"
},
{
"db_name": "UniProt",
"db_id": "P11504"
},
{
"db_name": "UniProt",
"db_id": "P20074"
},
{
"db_name": "UniProt",
"db_id": "P22782"
},
{
"db_name": "UniProt",
"db_id": "P25309"
},
{
"db_name": "UniProt",
"db_id": "P25819"
},
{
"db_name": "UniProt",
"db_id": "P26825"
},
{
"db_name": "UniProt",
"db_id": "P26826"
},
{
"db_name": "UniProt",
"db_id": "P32796"
},
{
"db_name": "UniProt",
"db_id": "P36882"
},
{
"db_name": "UniProt",
"db_id": "P36883"
},
{
"db_name": "UniProt",
"db_id": "P43155"
},
{
"db_name": "UniProt",
"db_id": "P47934"
},
{
"db_name": "UniProt",
"db_id": "P49417"
},
{
"db_name": "UniProt",
"db_id": "P52826"
},
{
"db_name": "UniProt",
"db_id": "P58777"
},
{
"db_name": "UniProt",
"db_id": "P62577"
},
{
"db_name": "UniProt",
"db_id": "P62578"
},
{
"db_name": "UniProt",
"db_id": "P62579"
},
{
"db_name": "UniProt",
"db_id": "P62580"
},
{
"db_name": "UniProt",
"db_id": "P90682"
},
{
"db_name": "UniProt",
"db_id": "Q00614"
},
{
"db_name": "UniProt",
"db_id": "Q02736"
},
{
"db_name": "UniProt",
"db_id": "Q03058"
},
{
"db_name": "UniProt",
"db_id": "Q5RF10"
},
{
"db_name": "UniProt",
"db_id": "Q64405"
},
{
"db_name": "UniProt",
"db_id": "Q704S8"
},
{
"db_name": "UniProt",
"db_id": "Q9M5L6"
},
{
"db_name": "UniProt",
"db_id": "Q9PWF7"
}
]
},
{
"id": "DS.d23.s0.e3",
"type": "compound",
"text": [
"proline"
],
"offsets": [
[
246,
253
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "614"
},
{
"db_name": "PubChem",
"db_id": "8988"
},
{
"db_name": "PubChem",
"db_id": "145742"
}
]
},
{
"id": "DS.d23.s0.e4",
"type": "protein",
"text": [
"superoxide dismutase"
],
"offsets": [
[
264,
284
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O50258"
}
]
},
{
"id": "DS.d23.s0.e5",
"type": "protein",
"text": [
"SOD"
],
"offsets": [
[
286,
289
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12933"
},
{
"db_name": "UniProt",
"db_id": "O22668"
},
{
"db_name": "UniProt",
"db_id": "O75007"
},
{
"db_name": "UniProt",
"db_id": "P24705"
},
{
"db_name": "UniProt",
"db_id": "P51547"
},
{
"db_name": "UniProt",
"db_id": "P93258"
},
{
"db_name": "UniProt",
"db_id": "Q01137"
},
{
"db_name": "UniProt",
"db_id": "Q27666"
},
{
"db_name": "UniProt",
"db_id": "Q9SM64"
}
]
},
{
"id": "DS.d23.s0.e6",
"type": "protein",
"text": [
"peroxidase"
],
"offsets": [
[
295,
305
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P15984"
},
{
"db_name": "UniProt",
"db_id": "P16147"
},
{
"db_name": "UniProt",
"db_id": "P84714"
}
]
},
{
"id": "DS.d23.s0.e7",
"type": "protein",
"text": [
"POD"
],
"offsets": [
[
307,
310
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P59097"
},
{
"db_name": "UniProt",
"db_id": "P79076"
},
{
"db_name": "UniProt",
"db_id": "Q5B2E9"
},
{
"db_name": "UniProt",
"db_id": "Q5G234"
},
{
"db_name": "UniProt",
"db_id": "Q6QWR1"
},
{
"db_name": "UniProt",
"db_id": "Q6UG02"
},
{
"db_name": "UniProt",
"db_id": "Q75ZP8"
},
{
"db_name": "UniProt",
"db_id": "Q8J136"
},
{
"db_name": "UniProt",
"db_id": "Q8J2V8"
}
]
},
{
"id": "DS.d23.s0.e8",
"type": "protein",
"text": [
"LPO"
],
"offsets": [
[
328,
331
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P22079"
},
{
"db_name": "UniProt",
"db_id": "P80025"
}
]
}
] | [] | [] | [] |
DS.d24 | 18068270 | [
{
"id": "DS.d24.s0",
"text": [
"Selenium and aluminum levels were not associated to CSF Abeta42."
],
"offsets": [
[
0,
64
]
],
"type": ""
},
{
"id": "DS.d24.s1",
"text": [
"In vitro, the degradation of synthetic Abeta substrate added to CSF was markedly accelerated by low levels (2microM) of exogenous zinc and copper."
],
"offsets": [
[
65,
211
]
],
"type": ""
}
] | [
{
"id": "DS.d24.s0.e0",
"type": "compound",
"text": [
"aluminum"
],
"offsets": [
[
13,
21
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5359268"
}
]
},
{
"id": "DS.d24.s0.e1",
"type": "protein",
"text": [
"CSF"
],
"offsets": [
[
52,
55
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62757"
},
{
"db_name": "UniProt",
"db_id": "P01587"
},
{
"db_name": "UniProt",
"db_id": "P04141"
},
{
"db_name": "UniProt",
"db_id": "P11052"
},
{
"db_name": "UniProt",
"db_id": "P28773"
},
{
"db_name": "UniProt",
"db_id": "P48749"
},
{
"db_name": "UniProt",
"db_id": "P48750"
},
{
"db_name": "UniProt",
"db_id": "P51748"
},
{
"db_name": "UniProt",
"db_id": "Q0MUT8"
},
{
"db_name": "UniProt",
"db_id": "Q29118"
},
{
"db_name": "UniProt",
"db_id": "Q60481"
}
]
},
{
"id": "DS.d24.s1.e0",
"type": "protein",
"text": [
"CSF"
],
"offsets": [
[
129,
132
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62757"
},
{
"db_name": "UniProt",
"db_id": "P01587"
},
{
"db_name": "UniProt",
"db_id": "P04141"
},
{
"db_name": "UniProt",
"db_id": "P11052"
},
{
"db_name": "UniProt",
"db_id": "P28773"
},
{
"db_name": "UniProt",
"db_id": "P48749"
},
{
"db_name": "UniProt",
"db_id": "P48750"
},
{
"db_name": "UniProt",
"db_id": "P51748"
},
{
"db_name": "UniProt",
"db_id": "Q0MUT8"
},
{
"db_name": "UniProt",
"db_id": "Q29118"
},
{
"db_name": "UniProt",
"db_id": "Q60481"
}
]
},
{
"id": "DS.d24.s1.e1",
"type": "compound",
"text": [
"copper"
],
"offsets": [
[
204,
210
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "23978"
}
]
}
] | [] | [] | [
{
"id": "DS.d24.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d24.s1.e1",
"arg2_id": "DS.d24.s1.e0",
"normalized": []
}
] |
DS.d25 | 18068871 | [
{
"id": "DS.d25.s0",
"text": [
"Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices."
],
"offsets": [
[
0,
127
]
],
"type": ""
},
{
"id": "DS.d25.s1",
"text": [
"Similarly, mutant PS1 impairs the ability of the cholinesterase inhibitor phenserine to enhance LTP."
],
"offsets": [
[
128,
228
]
],
"type": ""
}
] | [
{
"id": "DS.d25.s0.e0",
"type": "protein",
"text": [
"Presenilin-1"
],
"offsets": [
[
0,
12
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12976"
},
{
"db_name": "UniProt",
"db_id": "P49768"
},
{
"db_name": "UniProt",
"db_id": "P49769"
},
{
"db_name": "UniProt",
"db_id": "P79802"
},
{
"db_name": "UniProt",
"db_id": "P97887"
},
{
"db_name": "UniProt",
"db_id": "Q4JIM4"
},
{
"db_name": "UniProt",
"db_id": "Q5R780"
},
{
"db_name": "UniProt",
"db_id": "Q6RH31"
},
{
"db_name": "UniProt",
"db_id": "Q8HXW5"
},
{
"db_name": "UniProt",
"db_id": "Q9W6T7"
},
{
"db_name": "UniProt",
"db_id": "Q9XT97"
}
]
},
{
"id": "DS.d25.s0.e1",
"type": "compound",
"text": [
"NMDA"
],
"offsets": [
[
91,
95
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "22880"
}
]
},
{
"id": "DS.d25.s1.e0",
"type": "protein",
"text": [
"PS1"
],
"offsets": [
[
146,
149
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P49768"
},
{
"db_name": "UniProt",
"db_id": "P79802"
},
{
"db_name": "UniProt",
"db_id": "Q8HXW5"
},
{
"db_name": "UniProt",
"db_id": "Q9W6T7"
}
]
},
{
"id": "DS.d25.s1.e1",
"type": "compound",
"text": [
"phenserine"
],
"offsets": [
[
202,
212
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "192706"
},
{
"db_name": "PubChem",
"db_id": "9905831"
},
{
"db_name": "PubChem",
"db_id": "10337156"
}
]
}
] | [] | [] | [
{
"id": "DS.d25.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d25.s0.e1",
"arg2_id": "DS.d25.s0.e0",
"normalized": []
},
{
"id": "DS.d25.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d25.s1.e1",
"arg2_id": "DS.d25.s1.e0",
"normalized": []
}
] |
DS.d26 | 18077014 | [
{
"id": "DS.d26.s0",
"text": [
"It was found that the expression of SSAT and ODC were upregulated after reperfusion and the concentrations of spermidine and spermine were significantly decreased, while putrescine concentration was significantly increased."
],
"offsets": [
[
0,
223
]
],
"type": ""
}
] | [
{
"id": "DS.d26.s0.e0",
"type": "protein",
"text": [
"SSAT"
],
"offsets": [
[
36,
40
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P21673"
},
{
"db_name": "UniProt",
"db_id": "P48026"
},
{
"db_name": "UniProt",
"db_id": "P49431"
},
{
"db_name": "UniProt",
"db_id": "Q01612"
},
{
"db_name": "UniProt",
"db_id": "Q28999"
},
{
"db_name": "UniProt",
"db_id": "Q3T0Q0"
},
{
"db_name": "UniProt",
"db_id": "Q8AXL1"
},
{
"db_name": "UniProt",
"db_id": "Q9JHW6"
}
]
},
{
"id": "DS.d26.s0.e1",
"type": "protein",
"text": [
"ODC"
],
"offsets": [
[
45,
48
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O22616"
},
{
"db_name": "UniProt",
"db_id": "P00860"
},
{
"db_name": "UniProt",
"db_id": "P07805"
},
{
"db_name": "UniProt",
"db_id": "P08432"
},
{
"db_name": "UniProt",
"db_id": "P09057"
},
{
"db_name": "UniProt",
"db_id": "P11926"
},
{
"db_name": "UniProt",
"db_id": "P14019"
},
{
"db_name": "UniProt",
"db_id": "P27116"
},
{
"db_name": "UniProt",
"db_id": "P27117"
},
{
"db_name": "UniProt",
"db_id": "P27118"
},
{
"db_name": "UniProt",
"db_id": "P27119"
},
{
"db_name": "UniProt",
"db_id": "P27121"
},
{
"db_name": "UniProt",
"db_id": "P40807"
},
{
"db_name": "UniProt",
"db_id": "P40808"
},
{
"db_name": "UniProt",
"db_id": "P41931"
},
{
"db_name": "UniProt",
"db_id": "P43099"
},
{
"db_name": "UniProt",
"db_id": "P49725"
},
{
"db_name": "UniProt",
"db_id": "P50134"
},
{
"db_name": "UniProt",
"db_id": "P78599"
},
{
"db_name": "UniProt",
"db_id": "Q5RFB7"
},
{
"db_name": "UniProt",
"db_id": "Q8S3N2"
},
{
"db_name": "UniProt",
"db_id": "Q92445"
},
{
"db_name": "UniProt",
"db_id": "Q9BQT8"
},
{
"db_name": "UniProt",
"db_id": "Q9UQW9"
}
]
},
{
"id": "DS.d26.s0.e2",
"type": "compound",
"text": [
"spermidine"
],
"offsets": [
[
110,
120
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1102"
}
]
},
{
"id": "DS.d26.s0.e3",
"type": "compound",
"text": [
"spermine"
],
"offsets": [
[
125,
133
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1103"
}
]
},
{
"id": "DS.d26.s0.e4",
"type": "compound",
"text": [
"putrescine"
],
"offsets": [
[
170,
180
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1045"
}
]
}
] | [] | [] | [
{
"id": "DS.d26.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d26.s0.e3",
"arg2_id": "DS.d26.s0.e1",
"normalized": []
},
{
"id": "DS.d26.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d26.s0.e4",
"arg2_id": "DS.d26.s0.e0",
"normalized": []
},
{
"id": "DS.d26.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d26.s0.e3",
"arg2_id": "DS.d26.s0.e0",
"normalized": []
},
{
"id": "DS.d26.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d26.s0.e4",
"arg2_id": "DS.d26.s0.e1",
"normalized": []
},
{
"id": "DS.d26.s0.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d26.s0.e2",
"arg2_id": "DS.d26.s0.e0",
"normalized": []
},
{
"id": "DS.d26.s0.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d26.s0.e2",
"arg2_id": "DS.d26.s0.e1",
"normalized": []
}
] |
DS.d27 | 18079026 | [
{
"id": "DS.d27.s0",
"text": [
"In the present study, we investigated the effects of quetiapine on memory impairment and pathological changes in an amyloid precursor protein (APP)/presenilin-1 (PS-1) double transgenic mouse model of Alzheimer's disease (AD)."
],
"offsets": [
[
0,
226
]
],
"type": ""
},
{
"id": "DS.d27.s1",
"text": [
"Quetiapine also decreased brain Abeta peptides, beta-secretase activity and expression, and the level of C99 (an APP C-terminal fragment following cleavage by beta-secretase) in the transgenic mice."
],
"offsets": [
[
227,
425
]
],
"type": ""
},
{
"id": "DS.d27.s2",
"text": [
"Furthermore, quetiapine attenuated anxiety-like behavior, up-regulated cerebral Bcl-2 protein, and decreased cerebral nitrotyrosine in the transgenic mice."
],
"offsets": [
[
426,
581
]
],
"type": ""
}
] | [
{
"id": "DS.d27.s0.e0",
"type": "compound",
"text": [
"quetiapine"
],
"offsets": [
[
53,
63
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5002"
}
]
},
{
"id": "DS.d27.s0.e1",
"type": "protein",
"text": [
"APP"
],
"offsets": [
[
143,
146
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O73683"
},
{
"db_name": "UniProt",
"db_id": "O93279"
},
{
"db_name": "UniProt",
"db_id": "P05067"
},
{
"db_name": "UniProt",
"db_id": "P08592"
},
{
"db_name": "UniProt",
"db_id": "P0A3Z1"
},
{
"db_name": "UniProt",
"db_id": "P0A3Z2"
},
{
"db_name": "UniProt",
"db_id": "P0A3Z3"
},
{
"db_name": "UniProt",
"db_id": "P0A3Z4"
},
{
"db_name": "UniProt",
"db_id": "P12023"
},
{
"db_name": "UniProt",
"db_id": "P29216"
},
{
"db_name": "UniProt",
"db_id": "P47566"
},
{
"db_name": "UniProt",
"db_id": "P53601"
},
{
"db_name": "UniProt",
"db_id": "P75313"
},
{
"db_name": "UniProt",
"db_id": "P79307"
},
{
"db_name": "UniProt",
"db_id": "Q11207"
},
{
"db_name": "UniProt",
"db_id": "Q28053"
},
{
"db_name": "UniProt",
"db_id": "Q28280"
},
{
"db_name": "UniProt",
"db_id": "Q28748"
},
{
"db_name": "UniProt",
"db_id": "Q28757"
},
{
"db_name": "UniProt",
"db_id": "Q29149"
},
{
"db_name": "UniProt",
"db_id": "Q5IS80"
},
{
"db_name": "UniProt",
"db_id": "Q60495"
},
{
"db_name": "UniProt",
"db_id": "Q95241"
}
]
},
{
"id": "DS.d27.s0.e2",
"type": "protein",
"text": [
"presenilin-1"
],
"offsets": [
[
148,
160
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12976"
},
{
"db_name": "UniProt",
"db_id": "P49768"
},
{
"db_name": "UniProt",
"db_id": "P49769"
},
{
"db_name": "UniProt",
"db_id": "P79802"
},
{
"db_name": "UniProt",
"db_id": "P97887"
},
{
"db_name": "UniProt",
"db_id": "Q4JIM4"
},
{
"db_name": "UniProt",
"db_id": "Q5R780"
},
{
"db_name": "UniProt",
"db_id": "Q6RH31"
},
{
"db_name": "UniProt",
"db_id": "Q8HXW5"
},
{
"db_name": "UniProt",
"db_id": "Q9W6T7"
},
{
"db_name": "UniProt",
"db_id": "Q9XT97"
}
]
},
{
"id": "DS.d27.s0.e3",
"type": "protein",
"text": [
"PS-1"
],
"offsets": [
[
162,
166
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P49768"
},
{
"db_name": "UniProt",
"db_id": "P49769"
},
{
"db_name": "UniProt",
"db_id": "P79802"
},
{
"db_name": "UniProt",
"db_id": "P84566"
},
{
"db_name": "UniProt",
"db_id": "P97887"
},
{
"db_name": "UniProt",
"db_id": "Q5R780"
},
{
"db_name": "UniProt",
"db_id": "Q6RH31"
},
{
"db_name": "UniProt",
"db_id": "Q8HXW5"
},
{
"db_name": "UniProt",
"db_id": "Q9XT97"
}
]
},
{
"id": "DS.d27.s1.e0",
"type": "compound",
"text": [
"Quetiapine"
],
"offsets": [
[
227,
237
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5002"
}
]
},
{
"id": "DS.d27.s1.e1",
"type": "protein",
"text": [
"C99"
],
"offsets": [
[
332,
335
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05067"
},
{
"db_name": "UniProt",
"db_id": "P08592"
},
{
"db_name": "UniProt",
"db_id": "P12023"
},
{
"db_name": "UniProt",
"db_id": "P53601"
},
{
"db_name": "UniProt",
"db_id": "P79307"
},
{
"db_name": "UniProt",
"db_id": "Q5IS80"
},
{
"db_name": "UniProt",
"db_id": "Q95241"
}
]
},
{
"id": "DS.d27.s1.e2",
"type": "protein",
"text": [
"APP"
],
"offsets": [
[
340,
343
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O73683"
},
{
"db_name": "UniProt",
"db_id": "O93279"
},
{
"db_name": "UniProt",
"db_id": "P05067"
},
{
"db_name": "UniProt",
"db_id": "P08592"
},
{
"db_name": "UniProt",
"db_id": "P0A3Z1"
},
{
"db_name": "UniProt",
"db_id": "P0A3Z2"
},
{
"db_name": "UniProt",
"db_id": "P0A3Z3"
},
{
"db_name": "UniProt",
"db_id": "P0A3Z4"
},
{
"db_name": "UniProt",
"db_id": "P12023"
},
{
"db_name": "UniProt",
"db_id": "P29216"
},
{
"db_name": "UniProt",
"db_id": "P47566"
},
{
"db_name": "UniProt",
"db_id": "P53601"
},
{
"db_name": "UniProt",
"db_id": "P75313"
},
{
"db_name": "UniProt",
"db_id": "P79307"
},
{
"db_name": "UniProt",
"db_id": "Q11207"
},
{
"db_name": "UniProt",
"db_id": "Q28053"
},
{
"db_name": "UniProt",
"db_id": "Q28280"
},
{
"db_name": "UniProt",
"db_id": "Q28748"
},
{
"db_name": "UniProt",
"db_id": "Q28757"
},
{
"db_name": "UniProt",
"db_id": "Q29149"
},
{
"db_name": "UniProt",
"db_id": "Q5IS80"
},
{
"db_name": "UniProt",
"db_id": "Q60495"
},
{
"db_name": "UniProt",
"db_id": "Q95241"
}
]
},
{
"id": "DS.d27.s2.e0",
"type": "compound",
"text": [
"quetiapine"
],
"offsets": [
[
439,
449
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5002"
}
]
},
{
"id": "DS.d27.s2.e1",
"type": "protein",
"text": [
"Bcl-2"
],
"offsets": [
[
506,
511
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10417"
},
{
"db_name": "UniProt",
"db_id": "P49950"
}
]
}
] | [] | [] | [
{
"id": "DS.d27.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d27.s1.e0",
"arg2_id": "DS.d27.s1.e1",
"normalized": []
},
{
"id": "DS.d27.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d27.s1.e0",
"arg2_id": "DS.d27.s1.e2",
"normalized": []
},
{
"id": "DS.d27.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d27.s2.e0",
"arg2_id": "DS.d27.s2.e1",
"normalized": []
}
] |
DS.d28 | 18162361 | [
{
"id": "DS.d28.s0",
"text": [
"Rosuvastatin rapidly phosphorylated Akt and endothelial nitric oxide synthase (eNOS) in human endothelial cells."
],
"offsets": [
[
0,
112
]
],
"type": ""
},
{
"id": "DS.d28.s1",
"text": [
"Our findings indicate that rosuvastatin protects endothelial cells from death with phosphorylation of Akt and eNOS."
],
"offsets": [
[
113,
228
]
],
"type": ""
}
] | [
{
"id": "DS.d28.s0.e0",
"type": "compound",
"text": [
"Rosuvastatin"
],
"offsets": [
[
0,
12
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "446157"
}
]
},
{
"id": "DS.d28.s0.e1",
"type": "protein",
"text": [
"Akt"
],
"offsets": [
[
36,
39
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P31750"
},
{
"db_name": "UniProt",
"db_id": "Q8INB9"
}
]
},
{
"id": "DS.d28.s0.e2",
"type": "protein",
"text": [
"nitric oxide synthase"
],
"offsets": [
[
56,
77
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O61309"
},
{
"db_name": "UniProt",
"db_id": "O61608"
},
{
"db_name": "UniProt",
"db_id": "Q27571"
},
{
"db_name": "UniProt",
"db_id": "Q9I9M2"
}
]
},
{
"id": "DS.d28.s0.e3",
"type": "protein",
"text": [
"eNOS"
],
"offsets": [
[
79,
83
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P29473"
},
{
"db_name": "UniProt",
"db_id": "P29474"
},
{
"db_name": "UniProt",
"db_id": "P70313"
},
{
"db_name": "UniProt",
"db_id": "P79209"
},
{
"db_name": "UniProt",
"db_id": "P97270"
},
{
"db_name": "UniProt",
"db_id": "Q28969"
},
{
"db_name": "UniProt",
"db_id": "Q62600"
}
]
},
{
"id": "DS.d28.s1.e0",
"type": "compound",
"text": [
"rosuvastatin"
],
"offsets": [
[
140,
152
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "446157"
}
]
},
{
"id": "DS.d28.s1.e1",
"type": "protein",
"text": [
"Akt"
],
"offsets": [
[
215,
218
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P31750"
},
{
"db_name": "UniProt",
"db_id": "Q8INB9"
}
]
},
{
"id": "DS.d28.s1.e2",
"type": "protein",
"text": [
"eNOS"
],
"offsets": [
[
223,
227
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P29473"
},
{
"db_name": "UniProt",
"db_id": "P29474"
},
{
"db_name": "UniProt",
"db_id": "P70313"
},
{
"db_name": "UniProt",
"db_id": "P79209"
},
{
"db_name": "UniProt",
"db_id": "P97270"
},
{
"db_name": "UniProt",
"db_id": "Q28969"
},
{
"db_name": "UniProt",
"db_id": "Q62600"
}
]
}
] | [] | [] | [
{
"id": "DS.d28.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d28.s0.e0",
"arg2_id": "DS.d28.s0.e2",
"normalized": []
},
{
"id": "DS.d28.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d28.s0.e0",
"arg2_id": "DS.d28.s0.e3",
"normalized": []
},
{
"id": "DS.d28.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d28.s0.e0",
"arg2_id": "DS.d28.s0.e1",
"normalized": []
},
{
"id": "DS.d28.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d28.s1.e0",
"arg2_id": "DS.d28.s1.e2",
"normalized": []
},
{
"id": "DS.d28.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d28.s1.e0",
"arg2_id": "DS.d28.s1.e1",
"normalized": []
}
] |
DS.d29 | 18164165 | [
{
"id": "DS.d29.s0",
"text": [
"Superoxide dismutase and glutathione peroxidase antioxidant enzyme activities and malondialdehyde levels were found to be increased; however, beta-carotene, retinol, vitamin C, vitamin E, reduced glutathione, and albumin levels were observed to be significantly decreased."
],
"offsets": [
[
0,
272
]
],
"type": ""
}
] | [
{
"id": "DS.d29.s0.e0",
"type": "protein",
"text": [
"Superoxide dismutase"
],
"offsets": [
[
0,
20
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O50258"
}
]
},
{
"id": "DS.d29.s0.e1",
"type": "protein",
"text": [
"glutathione peroxidase"
],
"offsets": [
[
25,
47
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O32770"
},
{
"db_name": "UniProt",
"db_id": "O59858"
},
{
"db_name": "UniProt",
"db_id": "Q00277"
},
{
"db_name": "UniProt",
"db_id": "Q9CFV1"
}
]
},
{
"id": "DS.d29.s0.e2",
"type": "compound",
"text": [
"malondialdehyde"
],
"offsets": [
[
82,
97
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "10964"
}
]
},
{
"id": "DS.d29.s0.e3",
"type": "compound",
"text": [
"beta-carotene"
],
"offsets": [
[
142,
155
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5280489"
}
]
},
{
"id": "DS.d29.s0.e4",
"type": "compound",
"text": [
"retinol"
],
"offsets": [
[
157,
164
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "445354"
}
]
},
{
"id": "DS.d29.s0.e5",
"type": "compound",
"text": [
"vitamin C"
],
"offsets": [
[
166,
175
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "54670067"
}
]
},
{
"id": "DS.d29.s0.e6",
"type": "compound",
"text": [
"vitamin E"
],
"offsets": [
[
177,
186
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2116"
},
{
"db_name": "PubChem",
"db_id": "14985"
},
{
"db_name": "PubChem",
"db_id": "1548900"
},
{
"db_name": "PubChem",
"db_id": "1742129"
}
]
},
{
"id": "DS.d29.s0.e7",
"type": "compound",
"text": [
"reduced glutathione"
],
"offsets": [
[
188,
207
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
}
] | [] | [] | [] |
DS.d30 | 18172601 | [
{
"id": "DS.d30.s0",
"text": [
"Structure-function studies of nitrated SERCA2 in aging heart and skeletal muscle demonstrate stoichiometric nitration of vicinal tyrosines, Tyr (294) and Tyr (295), on the lumenal side of the membrane-spanning helix, M4, which correlates with partial inhibition of Ca(2+)-ATPase activity suggesting a possible regulatory function in down-regulating mitochondrial energy production and the associated generation of reactive oxygen/nitrogen species."
],
"offsets": [
[
0,
447
]
],
"type": ""
}
] | [
{
"id": "DS.d30.s0.e0",
"type": "protein",
"text": [
"SERCA2"
],
"offsets": [
[
39,
45
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O46674"
},
{
"db_name": "UniProt",
"db_id": "O55143"
},
{
"db_name": "UniProt",
"db_id": "P11507"
},
{
"db_name": "UniProt",
"db_id": "P11607"
},
{
"db_name": "UniProt",
"db_id": "P16615"
},
{
"db_name": "UniProt",
"db_id": "P20647"
},
{
"db_name": "UniProt",
"db_id": "Q00779"
},
{
"db_name": "UniProt",
"db_id": "Q03669"
}
]
},
{
"id": "DS.d30.s0.e1",
"type": "compound",
"text": [
"M4"
],
"offsets": [
[
217,
219
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "16682741"
}
]
},
{
"id": "DS.d30.s0.e2",
"type": "compound",
"text": [
"oxygen"
],
"offsets": [
[
423,
429
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "977"
}
]
},
{
"id": "DS.d30.s0.e3",
"type": "compound",
"text": [
"nitrogen"
],
"offsets": [
[
430,
438
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "947"
},
{
"db_name": "PubChem",
"db_id": "123329"
}
]
}
] | [] | [] | [] |
DS.d31 | 18177531 | [
{
"id": "DS.d31.s0",
"text": [
"Carbon monoxide is an endogenous vasodilator gas produced by the enzyme heme oxygenase (HO)."
],
"offsets": [
[
0,
92
]
],
"type": ""
}
] | [
{
"id": "DS.d31.s0.e0",
"type": "compound",
"text": [
"Carbon monoxide"
],
"offsets": [
[
0,
15
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "281"
}
]
},
{
"id": "DS.d31.s0.e1",
"type": "protein",
"text": [
"heme oxygenase"
],
"offsets": [
[
72,
86
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O19998"
},
{
"db_name": "UniProt",
"db_id": "O73688"
},
{
"db_name": "UniProt",
"db_id": "O78497"
},
{
"db_name": "UniProt",
"db_id": "P51271"
},
{
"db_name": "UniProt",
"db_id": "P71119"
}
]
}
] | [] | [] | [
{
"id": "DS.d31.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d31.s0.e0",
"arg2_id": "DS.d31.s0.e1",
"normalized": []
}
] |
DS.d32 | 18179560 | [
{
"id": "DS.d32.s0",
"text": [
"The long pentraxin 3 (PTX3) is a multifunctional soluble pattern recognition receptor, involved in several processes ranging from innate resistance and inflammation to clearance of apoptotic cells and organization of hyaluronic acid-rich extracellular matrices."
],
"offsets": [
[
0,
261
]
],
"type": ""
}
] | [
{
"id": "DS.d32.s0.e0",
"type": "protein",
"text": [
"PTX3"
],
"offsets": [
[
22,
26
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O75364"
},
{
"db_name": "UniProt",
"db_id": "P26022"
}
]
},
{
"id": "DS.d32.s0.e1",
"type": "compound",
"text": [
"hyaluronic acid"
],
"offsets": [
[
217,
232
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "24759"
},
{
"db_name": "PubChem",
"db_id": "453618"
},
{
"db_name": "PubChem",
"db_id": "3084050"
},
{
"db_name": "PubChem",
"db_id": "24728612"
}
]
}
] | [] | [] | [
{
"id": "DS.d32.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d32.s0.e1",
"arg2_id": "DS.d32.s0.e0",
"normalized": []
}
] |
DS.d33 | 18180755 | [
{
"id": "DS.d33.s0",
"text": [
"The FKBP5 gene product forms part of a complex with the glucocorticoid receptor and can modulate cortisol-binding affinity."
],
"offsets": [
[
0,
123
]
],
"type": ""
}
] | [
{
"id": "DS.d33.s0.e0",
"type": "protein",
"text": [
"FKBP5"
],
"offsets": [
[
4,
9
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0C1J7"
},
{
"db_name": "UniProt",
"db_id": "Q13451"
},
{
"db_name": "UniProt",
"db_id": "Q5RF88"
},
{
"db_name": "UniProt",
"db_id": "Q95L05"
},
{
"db_name": "UniProt",
"db_id": "Q9XSH5"
},
{
"db_name": "UniProt",
"db_id": "Q9XSI2"
},
{
"db_name": "UniProt",
"db_id": "Q9XT11"
}
]
},
{
"id": "DS.d33.s0.e1",
"type": "protein",
"text": [
"glucocorticoid receptor"
],
"offsets": [
[
56,
79
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O13186"
},
{
"db_name": "UniProt",
"db_id": "O46567"
},
{
"db_name": "UniProt",
"db_id": "O73673"
},
{
"db_name": "UniProt",
"db_id": "P04150"
},
{
"db_name": "UniProt",
"db_id": "P06536"
},
{
"db_name": "UniProt",
"db_id": "P06537"
},
{
"db_name": "UniProt",
"db_id": "P35547"
},
{
"db_name": "UniProt",
"db_id": "P49115"
},
{
"db_name": "UniProt",
"db_id": "P49843"
},
{
"db_name": "UniProt",
"db_id": "P49844"
},
{
"db_name": "UniProt",
"db_id": "P59667"
},
{
"db_name": "UniProt",
"db_id": "P79269"
},
{
"db_name": "UniProt",
"db_id": "P79686"
},
{
"db_name": "UniProt",
"db_id": "Q5R9P5"
},
{
"db_name": "UniProt",
"db_id": "Q6XLJ0"
},
{
"db_name": "UniProt",
"db_id": "Q95267"
},
{
"db_name": "UniProt",
"db_id": "Q9N1U3"
}
]
},
{
"id": "DS.d33.s0.e2",
"type": "compound",
"text": [
"cortisol"
],
"offsets": [
[
97,
105
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5754"
}
]
}
] | [] | [] | [
{
"id": "DS.d33.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d33.s0.e2",
"arg2_id": "DS.d33.s0.e0",
"normalized": []
},
{
"id": "DS.d33.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d33.s0.e2",
"arg2_id": "DS.d33.s0.e1",
"normalized": []
}
] |
DS.d34 | 18190985 | [
{
"id": "DS.d34.s0",
"text": [
"Several studies have shown that epsilon 2 carriers have lower low-density lipoprotein and apo B levels and higher high-density lipoprotein cholesterol and apo A-I levels than epsilon 3 carriers."
],
"offsets": [
[
0,
194
]
],
"type": ""
}
] | [
{
"id": "DS.d34.s0.e0",
"type": "protein",
"text": [
"epsilon"
],
"offsets": [
[
32,
39
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05463"
}
]
},
{
"id": "DS.d34.s0.e1",
"type": "protein",
"text": [
"high-density lipoprotein"
],
"offsets": [
[
114,
138
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P81182"
}
]
},
{
"id": "DS.d34.s0.e2",
"type": "compound",
"text": [
"cholesterol"
],
"offsets": [
[
139,
150
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "304"
},
{
"db_name": "PubChem",
"db_id": "5997"
},
{
"db_name": "PubChem",
"db_id": "6432564"
},
{
"db_name": "PubChem",
"db_id": "11025495"
}
]
},
{
"id": "DS.d34.s0.e3",
"type": "protein",
"text": [
"epsilon"
],
"offsets": [
[
175,
182
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05463"
}
]
}
] | [] | [] | [
{
"id": "DS.d34.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d34.s0.e2",
"arg2_id": "DS.d34.s0.e1",
"normalized": []
},
{
"id": "DS.d34.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d34.s0.e2",
"arg2_id": "DS.d34.s0.e0",
"normalized": []
}
] |
DS.d35 | 18191451 | [
{
"id": "DS.d35.s0",
"text": [
"Toxicity and characterization of cholinesterase-inhibition induced by diisopropyl fluorophosphate in Artemia salina larvae."
],
"offsets": [
[
0,
123
]
],
"type": ""
}
] | [
{
"id": "DS.d35.s0.e0",
"type": "protein",
"text": [
"cholinesterase"
],
"offsets": [
[
33,
47
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P32749"
},
{
"db_name": "UniProt",
"db_id": "P32750"
},
{
"db_name": "UniProt",
"db_id": "P32751"
},
{
"db_name": "UniProt",
"db_id": "P32752"
},
{
"db_name": "UniProt",
"db_id": "P32753"
},
{
"db_name": "UniProt",
"db_id": "P81908"
}
]
},
{
"id": "DS.d35.s0.e1",
"type": "compound",
"text": [
"diisopropyl fluorophosphate"
],
"offsets": [
[
70,
97
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5936"
}
]
}
] | [] | [] | [
{
"id": "DS.d35.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d35.s0.e1",
"arg2_id": "DS.d35.s0.e0",
"normalized": []
}
] |
DS.d36 | 18195714 | [
{
"id": "DS.d36.s0",
"text": [
"Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice."
],
"offsets": [
[
0,
114
]
],
"type": ""
},
{
"id": "DS.d36.s1",
"text": [
"We report that peripheral administration of lipopolysaccharide (LPS) activates IDO and culminates in a distinct depressive-like behavioral syndrome, measured by increased duration of immobility in both the forced-swim and tail suspension tests."
],
"offsets": [
[
115,
359
]
],
"type": ""
},
{
"id": "DS.d36.s2",
"text": [
"Administration of L-kynurenine, a metabolite of tryptophan that is generated by IDO, to naive mice dose dependently induces depressive-like behavior."
],
"offsets": [
[
360,
509
]
],
"type": ""
}
] | [
{
"id": "DS.d36.s0.e0",
"type": "compound",
"text": [
"Lipopolysaccharide"
],
"offsets": [
[
0,
18
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "11970143"
}
]
},
{
"id": "DS.d36.s0.e1",
"type": "protein",
"text": [
"indoleamine 2,3-dioxygenase"
],
"offsets": [
[
67,
94
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P14902"
},
{
"db_name": "UniProt",
"db_id": "P28776"
}
]
},
{
"id": "DS.d36.s1.e0",
"type": "compound",
"text": [
"lipopolysaccharide"
],
"offsets": [
[
159,
177
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "11970143"
}
]
},
{
"id": "DS.d36.s1.e1",
"type": "protein",
"text": [
"IDO"
],
"offsets": [
[
194,
197
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P14902"
},
{
"db_name": "UniProt",
"db_id": "P28776"
}
]
},
{
"id": "DS.d36.s2.e0",
"type": "compound",
"text": [
"kynurenine"
],
"offsets": [
[
380,
390
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "846"
}
]
},
{
"id": "DS.d36.s2.e1",
"type": "compound",
"text": [
"tryptophan"
],
"offsets": [
[
408,
418
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "1148"
},
{
"db_name": "PubChem",
"db_id": "6305"
},
{
"db_name": "PubChem",
"db_id": "9060"
},
{
"db_name": "PubChem",
"db_id": "5460840"
}
]
},
{
"id": "DS.d36.s2.e2",
"type": "protein",
"text": [
"IDO"
],
"offsets": [
[
440,
443
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P14902"
},
{
"db_name": "UniProt",
"db_id": "P28776"
}
]
}
] | [] | [] | [
{
"id": "DS.d36.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d36.s0.e0",
"arg2_id": "DS.d36.s0.e1",
"normalized": []
},
{
"id": "DS.d36.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d36.s1.e0",
"arg2_id": "DS.d36.s1.e1",
"normalized": []
},
{
"id": "DS.d36.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d36.s2.e0",
"arg2_id": "DS.d36.s2.e2",
"normalized": []
},
{
"id": "DS.d36.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d36.s2.e1",
"arg2_id": "DS.d36.s2.e2",
"normalized": []
}
] |
DS.d37 | 18198986 | [
{
"id": "DS.d37.s0",
"text": [
"Serum adipocyte fatty acid binding protein levels in patients with type 2 diabetes mellitus and obesity: the influence of fenofibrate treatment."
],
"offsets": [
[
0,
144
]
],
"type": ""
},
{
"id": "DS.d37.s1",
"text": [
"Serum FABP levels were 2.5-fold higher in T2DM group relative to C and were not affected by fenofibrate treatment (C: 20.6+/-2.1 microg/l, T2DM before F: 55.6+/-5.7 microg/l, T2DM after F: 54.2+/-5.4 microg/l, p 0.0001 for C vs. T2DM before F)."
],
"offsets": [
[
145,
389
]
],
"type": ""
},
{
"id": "DS.d37.s2",
"text": [
"FABP levels positively correlated with BMI, triglyceride levels, blood glucose, glycated hemoglobin, atherogenic index and insulin levels."
],
"offsets": [
[
390,
528
]
],
"type": ""
}
] | [
{
"id": "DS.d37.s0.e0",
"type": "protein",
"text": [
"fatty acid binding protein"
],
"offsets": [
[
16,
42
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O42494"
},
{
"db_name": "UniProt",
"db_id": "O45035"
},
{
"db_name": "UniProt",
"db_id": "O76821"
},
{
"db_name": "UniProt",
"db_id": "P80547"
},
{
"db_name": "UniProt",
"db_id": "Q17284"
},
{
"db_name": "UniProt",
"db_id": "Q8MUC1"
},
{
"db_name": "UniProt",
"db_id": "Q9U5P1"
}
]
},
{
"id": "DS.d37.s0.e1",
"type": "compound",
"text": [
"fenofibrate"
],
"offsets": [
[
122,
133
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3339"
}
]
},
{
"id": "DS.d37.s1.e0",
"type": "protein",
"text": [
"FABP"
],
"offsets": [
[
151,
155
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P80565"
}
]
},
{
"id": "DS.d37.s1.e1",
"type": "compound",
"text": [
"fenofibrate"
],
"offsets": [
[
237,
248
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3339"
}
]
},
{
"id": "DS.d37.s2.e0",
"type": "protein",
"text": [
"FABP"
],
"offsets": [
[
390,
394
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P80565"
}
]
},
{
"id": "DS.d37.s2.e1",
"type": "compound",
"text": [
"glucose"
],
"offsets": [
[
461,
468
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "206"
},
{
"db_name": "PubChem",
"db_id": "5793"
},
{
"db_name": "PubChem",
"db_id": "64689"
},
{
"db_name": "PubChem",
"db_id": "79025"
}
]
},
{
"id": "DS.d37.s2.e2",
"type": "protein",
"text": [
"hemoglobin"
],
"offsets": [
[
479,
489
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P15160"
},
{
"db_name": "UniProt",
"db_id": "P17724"
},
{
"db_name": "UniProt",
"db_id": "P73925"
},
{
"db_name": "UniProt",
"db_id": "Q03459"
}
]
},
{
"id": "DS.d37.s2.e3",
"type": "protein",
"text": [
"insulin"
],
"offsets": [
[
513,
520
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01314"
},
{
"db_name": "UniProt",
"db_id": "P01316"
},
{
"db_name": "UniProt",
"db_id": "P01319"
},
{
"db_name": "UniProt",
"db_id": "P01320"
},
{
"db_name": "UniProt",
"db_id": "P01324"
},
{
"db_name": "UniProt",
"db_id": "P01328"
},
{
"db_name": "UniProt",
"db_id": "P01330"
},
{
"db_name": "UniProt",
"db_id": "P01331"
},
{
"db_name": "UniProt",
"db_id": "P01334"
},
{
"db_name": "UniProt",
"db_id": "P01336"
},
{
"db_name": "UniProt",
"db_id": "P01340"
},
{
"db_name": "UniProt",
"db_id": "P07453"
},
{
"db_name": "UniProt",
"db_id": "P09476"
},
{
"db_name": "UniProt",
"db_id": "P09477"
},
{
"db_name": "UniProt",
"db_id": "P0C236"
},
{
"db_name": "UniProt",
"db_id": "P12703"
},
{
"db_name": "UniProt",
"db_id": "P12704"
},
{
"db_name": "UniProt",
"db_id": "P12708"
},
{
"db_name": "UniProt",
"db_id": "P13190"
},
{
"db_name": "UniProt",
"db_id": "P18109"
},
{
"db_name": "UniProt",
"db_id": "P29335"
},
{
"db_name": "UniProt",
"db_id": "P42633"
},
{
"db_name": "UniProt",
"db_id": "P67968"
},
{
"db_name": "UniProt",
"db_id": "P67969"
},
{
"db_name": "UniProt",
"db_id": "P67971"
},
{
"db_name": "UniProt",
"db_id": "P67973"
},
{
"db_name": "UniProt",
"db_id": "P67974"
},
{
"db_name": "UniProt",
"db_id": "P68243"
},
{
"db_name": "UniProt",
"db_id": "P68245"
},
{
"db_name": "UniProt",
"db_id": "P68987"
},
{
"db_name": "UniProt",
"db_id": "P68988"
},
{
"db_name": "UniProt",
"db_id": "P68989"
},
{
"db_name": "UniProt",
"db_id": "P68990"
},
{
"db_name": "UniProt",
"db_id": "P68991"
},
{
"db_name": "UniProt",
"db_id": "P68992"
},
{
"db_name": "UniProt",
"db_id": "P69046"
},
{
"db_name": "UniProt",
"db_id": "P69047"
},
{
"db_name": "UniProt",
"db_id": "P69048"
},
{
"db_name": "UniProt",
"db_id": "P81423"
},
{
"db_name": "UniProt",
"db_id": "P81881"
},
{
"db_name": "UniProt",
"db_id": "Q9TQY7"
}
]
}
] | [] | [] | [
{
"id": "DS.d37.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d37.s2.e1",
"arg2_id": "DS.d37.s2.e0",
"normalized": []
}
] |
DS.d38 | 18198997 | [
{
"id": "DS.d38.s0",
"text": [
"Butyrate enemas upregulate Muc genes expression but decrease adherent mucus thickness in mice colon."
],
"offsets": [
[
0,
100
]
],
"type": ""
},
{
"id": "DS.d38.s1",
"text": [
"We demonstrated that butyrate stimulated the gene expression of both secreted (Muc2) and membrane-linked (Muc1, Muc3, Muc4) mucins."
],
"offsets": [
[
101,
232
]
],
"type": ""
},
{
"id": "DS.d38.s2",
"text": [
"Butyrate especially induced a 6-fold increase in Muc2 gene expression in proximal colon."
],
"offsets": [
[
233,
321
]
],
"type": ""
},
{
"id": "DS.d38.s3",
"text": [
"However, butyrate enemas did not modify the number of epithelial cells containing the protein Muc2, and caused a 2-fold decrease in the thickness of adherent mucus layer."
],
"offsets": [
[
322,
492
]
],
"type": ""
}
] | [
{
"id": "DS.d38.s0.e0",
"type": "compound",
"text": [
"Butyrate"
],
"offsets": [
[
0,
8
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "264"
}
]
},
{
"id": "DS.d38.s0.e1",
"type": "protein",
"text": [
"Muc"
],
"offsets": [
[
27,
30
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P0A9M0"
}
]
},
{
"id": "DS.d38.s1.e0",
"type": "compound",
"text": [
"butyrate"
],
"offsets": [
[
122,
130
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "264"
}
]
},
{
"id": "DS.d38.s1.e1",
"type": "protein",
"text": [
"Muc2"
],
"offsets": [
[
180,
184
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q62635"
}
]
},
{
"id": "DS.d38.s1.e2",
"type": "protein",
"text": [
"Muc1"
],
"offsets": [
[
207,
211
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q02496"
}
]
},
{
"id": "DS.d38.s2.e0",
"type": "compound",
"text": [
"Butyrate"
],
"offsets": [
[
233,
241
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "264"
}
]
},
{
"id": "DS.d38.s2.e1",
"type": "protein",
"text": [
"Muc2"
],
"offsets": [
[
282,
286
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q62635"
}
]
},
{
"id": "DS.d38.s3.e0",
"type": "compound",
"text": [
"butyrate"
],
"offsets": [
[
331,
339
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "264"
}
]
},
{
"id": "DS.d38.s3.e1",
"type": "protein",
"text": [
"Muc2"
],
"offsets": [
[
416,
420
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q62635"
}
]
}
] | [] | [] | [
{
"id": "DS.d38.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d38.s0.e0",
"arg2_id": "DS.d38.s0.e1",
"normalized": []
},
{
"id": "DS.d38.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d38.s1.e0",
"arg2_id": "DS.d38.s1.e1",
"normalized": []
},
{
"id": "DS.d38.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d38.s1.e0",
"arg2_id": "DS.d38.s1.e2",
"normalized": []
},
{
"id": "DS.d38.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d38.s2.e0",
"arg2_id": "DS.d38.s2.e1",
"normalized": []
}
] |
DS.d39 | 18204887 | [
{
"id": "DS.d39.s0",
"text": [
"We examined the association of MTHFR C677T and A1298C, and changes in plasma homocysteine in 352 Tunisian patients with angiographically-demonstrated CAD, and 390 age and gender-matched healthy subjects."
],
"offsets": [
[
0,
203
]
],
"type": ""
}
] | [
{
"id": "DS.d39.s0.e0",
"type": "protein",
"text": [
"MTHFR"
],
"offsets": [
[
31,
36
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P42898"
},
{
"db_name": "UniProt",
"db_id": "Q5I598"
},
{
"db_name": "UniProt",
"db_id": "Q60HE5"
}
]
},
{
"id": "DS.d39.s0.e1",
"type": "compound",
"text": [
"homocysteine"
],
"offsets": [
[
77,
89
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "778"
}
]
}
] | [] | [] | [] |
DS.d40 | 18205042 | [
{
"id": "DS.d40.s0",
"text": [
"However, we also observed that clotrimazol (1alpha-hydroxylase inhibitor) enhanced 25(OH)D(3)-induced CYP24 expression in breast cancer cells."
],
"offsets": [
[
0,
142
]
],
"type": ""
}
] | [
{
"id": "DS.d40.s0.e0",
"type": "compound",
"text": [
"clotrimazol"
],
"offsets": [
[
31,
42
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2812"
}
]
},
{
"id": "DS.d40.s0.e1",
"type": "protein",
"text": [
"CYP24"
],
"offsets": [
[
102,
107
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q07973"
}
]
}
] | [] | [] | [
{
"id": "DS.d40.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d40.s0.e0",
"arg2_id": "DS.d40.s0.e1",
"normalized": []
}
] |
DS.d41 | 18207583 | [
{
"id": "DS.d41.s0",
"text": [
"Expression of senescence-associated beta-galactosidase (SA-beta-Gal) by human skin fibroblasts, effect of advanced glycation end-products and fucose or rhamnose-rich polysaccharides."
],
"offsets": [
[
0,
182
]
],
"type": ""
}
] | [
{
"id": "DS.d41.s0.e0",
"type": "protein",
"text": [
"beta-galactosidase"
],
"offsets": [
[
36,
54
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O33815"
},
{
"db_name": "UniProt",
"db_id": "O52629"
},
{
"db_name": "UniProt",
"db_id": "O52847"
},
{
"db_name": "UniProt",
"db_id": "P00722"
},
{
"db_name": "UniProt",
"db_id": "P00723"
},
{
"db_name": "UniProt",
"db_id": "P06219"
},
{
"db_name": "UniProt",
"db_id": "P0C1Y0"
},
{
"db_name": "UniProt",
"db_id": "P14288"
},
{
"db_name": "UniProt",
"db_id": "P22498"
},
{
"db_name": "UniProt",
"db_id": "P23989"
},
{
"db_name": "UniProt",
"db_id": "P24131"
},
{
"db_name": "UniProt",
"db_id": "P26257"
},
{
"db_name": "UniProt",
"db_id": "P30812"
},
{
"db_name": "UniProt",
"db_id": "P50388"
},
{
"db_name": "UniProt",
"db_id": "P70753"
},
{
"db_name": "UniProt",
"db_id": "P77989"
},
{
"db_name": "UniProt",
"db_id": "P81650"
},
{
"db_name": "UniProt",
"db_id": "Q1G9Z4"
},
{
"db_name": "UniProt",
"db_id": "Q47077"
},
{
"db_name": "UniProt",
"db_id": "Q48727"
},
{
"db_name": "UniProt",
"db_id": "Q56307"
},
{
"db_name": "UniProt",
"db_id": "Q59140"
},
{
"db_name": "UniProt",
"db_id": "Q59750"
},
{
"db_name": "UniProt",
"db_id": "Q9K9C6"
}
]
},
{
"id": "DS.d41.s0.e1",
"type": "protein",
"text": [
"Gal"
],
"offsets": [
[
64,
67
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10683"
},
{
"db_name": "UniProt",
"db_id": "P11886"
},
{
"db_name": "UniProt",
"db_id": "P47212"
}
]
},
{
"id": "DS.d41.s0.e2",
"type": "compound",
"text": [
"fucose"
],
"offsets": [
[
142,
148
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "840"
},
{
"db_name": "PubChem",
"db_id": "17106"
},
{
"db_name": "PubChem",
"db_id": "19466"
},
{
"db_name": "PubChem",
"db_id": "94270"
},
{
"db_name": "PubChem",
"db_id": "439554"
}
]
}
] | [] | [] | [] |
DS.d42 | 18221806 | [
{
"id": "DS.d42.s0",
"text": [
"Short-term withdrawal of simvastatin induces endothelial dysfunction in patients with coronary artery disease: a dose-response effect dependent on endothelial nitric oxide synthase."
],
"offsets": [
[
0,
181
]
],
"type": ""
}
] | [
{
"id": "DS.d42.s0.e0",
"type": "compound",
"text": [
"simvastatin"
],
"offsets": [
[
25,
36
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "54454"
},
{
"db_name": "PubChem",
"db_id": "4677798"
}
]
},
{
"id": "DS.d42.s0.e1",
"type": "protein",
"text": [
"nitric oxide synthase"
],
"offsets": [
[
159,
180
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O61309"
},
{
"db_name": "UniProt",
"db_id": "O61608"
},
{
"db_name": "UniProt",
"db_id": "Q27571"
},
{
"db_name": "UniProt",
"db_id": "Q9I9M2"
}
]
}
] | [] | [] | [
{
"id": "DS.d42.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d42.s0.e0",
"arg2_id": "DS.d42.s0.e1",
"normalized": []
}
] |
DS.d43 | 18222028 | [
{
"id": "DS.d43.s0",
"text": [
"It has been shown that the removal efficiency of COD increased with the increasing applied current density and increasing PAC and Na (2)SO(4) dosage and the most effective removal capacity was achieved at the pH 7."
],
"offsets": [
[
0,
214
]
],
"type": ""
}
] | [
{
"id": "DS.d43.s0.e0",
"type": "protein",
"text": [
"COD"
],
"offsets": [
[
49,
52
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P14678"
}
]
},
{
"id": "DS.d43.s0.e1",
"type": "compound",
"text": [
"Na"
],
"offsets": [
[
130,
132
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "923"
},
{
"db_name": "PubChem",
"db_id": "373840"
}
]
}
] | [] | [] | [
{
"id": "DS.d43.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d43.s0.e1",
"arg2_id": "DS.d43.s0.e0",
"normalized": []
}
] |
DS.d44 | 18222543 | [
{
"id": "DS.d44.s0",
"text": [
"The protective effects of novel synthetic organoselenium compounds (Se I and Se II) against DMBA-induced changes in levels of some (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR) activities and total glutathione (GSH), malonedialdehyde (MDA)) parameters in rat lung and kidney were investigated."
],
"offsets": [
[
0,
353
]
],
"type": ""
}
] | [
{
"id": "DS.d44.s0.e0",
"type": "compound",
"text": [
"DMBA"
],
"offsets": [
[
92,
96
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6001"
}
]
},
{
"id": "DS.d44.s0.e1",
"type": "protein",
"text": [
"superoxide dismutase"
],
"offsets": [
[
132,
152
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O50258"
}
]
},
{
"id": "DS.d44.s0.e2",
"type": "protein",
"text": [
"SOD"
],
"offsets": [
[
154,
157
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12933"
},
{
"db_name": "UniProt",
"db_id": "O22668"
},
{
"db_name": "UniProt",
"db_id": "O75007"
},
{
"db_name": "UniProt",
"db_id": "P24705"
},
{
"db_name": "UniProt",
"db_id": "P51547"
},
{
"db_name": "UniProt",
"db_id": "P93258"
},
{
"db_name": "UniProt",
"db_id": "Q01137"
},
{
"db_name": "UniProt",
"db_id": "Q27666"
},
{
"db_name": "UniProt",
"db_id": "Q9SM64"
}
]
},
{
"id": "DS.d44.s0.e3",
"type": "protein",
"text": [
"catalase"
],
"offsets": [
[
160,
168
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O24339"
},
{
"db_name": "UniProt",
"db_id": "O52762"
},
{
"db_name": "UniProt",
"db_id": "O62839"
},
{
"db_name": "UniProt",
"db_id": "O68146"
},
{
"db_name": "UniProt",
"db_id": "O77229"
},
{
"db_name": "UniProt",
"db_id": "O93662"
},
{
"db_name": "UniProt",
"db_id": "O97492"
},
{
"db_name": "UniProt",
"db_id": "P00432"
},
{
"db_name": "UniProt",
"db_id": "P04040"
},
{
"db_name": "UniProt",
"db_id": "P04762"
},
{
"db_name": "UniProt",
"db_id": "P07145"
},
{
"db_name": "UniProt",
"db_id": "P0A323"
},
{
"db_name": "UniProt",
"db_id": "P0A324"
},
{
"db_name": "UniProt",
"db_id": "P0A325"
},
{
"db_name": "UniProt",
"db_id": "P0A326"
},
{
"db_name": "UniProt",
"db_id": "P0A327"
},
{
"db_name": "UniProt",
"db_id": "P11934"
},
{
"db_name": "UniProt",
"db_id": "P17336"
},
{
"db_name": "UniProt",
"db_id": "P24168"
},
{
"db_name": "UniProt",
"db_id": "P24270"
},
{
"db_name": "UniProt",
"db_id": "P25890"
},
{
"db_name": "UniProt",
"db_id": "P29422"
},
{
"db_name": "UniProt",
"db_id": "P30265"
},
{
"db_name": "UniProt",
"db_id": "P30266"
},
{
"db_name": "UniProt",
"db_id": "P32290"
},
{
"db_name": "UniProt",
"db_id": "P42321"
},
{
"db_name": "UniProt",
"db_id": "P44390"
},
{
"db_name": "UniProt",
"db_id": "P45737"
},
{
"db_name": "UniProt",
"db_id": "P45739"
},
{
"db_name": "UniProt",
"db_id": "P55304"
},
{
"db_name": "UniProt",
"db_id": "P55306"
},
{
"db_name": "UniProt",
"db_id": "P55310"
},
{
"db_name": "UniProt",
"db_id": "P55311"
},
{
"db_name": "UniProt",
"db_id": "P55313"
},
{
"db_name": "UniProt",
"db_id": "P77872"
},
{
"db_name": "UniProt",
"db_id": "P81138"
},
{
"db_name": "UniProt",
"db_id": "P90682"
},
{
"db_name": "UniProt",
"db_id": "Q27710"
},
{
"db_name": "UniProt",
"db_id": "Q49XC1"
},
{
"db_name": "UniProt",
"db_id": "Q4L643"
},
{
"db_name": "UniProt",
"db_id": "Q59296"
},
{
"db_name": "UniProt",
"db_id": "Q59337"
},
{
"db_name": "UniProt",
"db_id": "Q59602"
},
{
"db_name": "UniProt",
"db_id": "Q59714"
},
{
"db_name": "UniProt",
"db_id": "Q5HG86"
},
{
"db_name": "UniProt",
"db_id": "Q5HPK8"
},
{
"db_name": "UniProt",
"db_id": "Q5RF10"
},
{
"db_name": "UniProt",
"db_id": "Q64405"
},
{
"db_name": "UniProt",
"db_id": "Q6G9M4"
},
{
"db_name": "UniProt",
"db_id": "Q6GH72"
},
{
"db_name": "UniProt",
"db_id": "Q7A5T2"
},
{
"db_name": "UniProt",
"db_id": "Q8CPD0"
},
{
"db_name": "UniProt",
"db_id": "Q8FWU0"
},
{
"db_name": "UniProt",
"db_id": "Q8NWV5"
},
{
"db_name": "UniProt",
"db_id": "Q8X1P0"
},
{
"db_name": "UniProt",
"db_id": "Q8Y3P9"
},
{
"db_name": "UniProt",
"db_id": "Q926X0"
},
{
"db_name": "UniProt",
"db_id": "Q99UE2"
},
{
"db_name": "UniProt",
"db_id": "Q9AXH0"
},
{
"db_name": "UniProt",
"db_id": "Q9KW19"
},
{
"db_name": "UniProt",
"db_id": "Q9L4S1"
},
{
"db_name": "UniProt",
"db_id": "Q9M5L6"
},
{
"db_name": "UniProt",
"db_id": "Q9PT92"
},
{
"db_name": "UniProt",
"db_id": "Q9PWF7"
},
{
"db_name": "UniProt",
"db_id": "Q9Z598"
},
{
"db_name": "UniProt",
"db_id": "Q9ZKX5"
},
{
"db_name": "UniProt",
"db_id": "Q9ZN99"
}
]
},
{
"id": "DS.d44.s0.e4",
"type": "protein",
"text": [
"CAT"
],
"offsets": [
[
170,
173
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62839"
},
{
"db_name": "UniProt",
"db_id": "O97492"
},
{
"db_name": "UniProt",
"db_id": "P00432"
},
{
"db_name": "UniProt",
"db_id": "P00485"
},
{
"db_name": "UniProt",
"db_id": "P00486"
},
{
"db_name": "UniProt",
"db_id": "P00487"
},
{
"db_name": "UniProt",
"db_id": "P04040"
},
{
"db_name": "UniProt",
"db_id": "P06135"
},
{
"db_name": "UniProt",
"db_id": "P07641"
},
{
"db_name": "UniProt",
"db_id": "P11504"
},
{
"db_name": "UniProt",
"db_id": "P20074"
},
{
"db_name": "UniProt",
"db_id": "P22782"
},
{
"db_name": "UniProt",
"db_id": "P25309"
},
{
"db_name": "UniProt",
"db_id": "P25819"
},
{
"db_name": "UniProt",
"db_id": "P26825"
},
{
"db_name": "UniProt",
"db_id": "P26826"
},
{
"db_name": "UniProt",
"db_id": "P32796"
},
{
"db_name": "UniProt",
"db_id": "P36882"
},
{
"db_name": "UniProt",
"db_id": "P36883"
},
{
"db_name": "UniProt",
"db_id": "P43155"
},
{
"db_name": "UniProt",
"db_id": "P47934"
},
{
"db_name": "UniProt",
"db_id": "P49417"
},
{
"db_name": "UniProt",
"db_id": "P52826"
},
{
"db_name": "UniProt",
"db_id": "P58777"
},
{
"db_name": "UniProt",
"db_id": "P62577"
},
{
"db_name": "UniProt",
"db_id": "P62578"
},
{
"db_name": "UniProt",
"db_id": "P62579"
},
{
"db_name": "UniProt",
"db_id": "P62580"
},
{
"db_name": "UniProt",
"db_id": "P90682"
},
{
"db_name": "UniProt",
"db_id": "Q00614"
},
{
"db_name": "UniProt",
"db_id": "Q02736"
},
{
"db_name": "UniProt",
"db_id": "Q03058"
},
{
"db_name": "UniProt",
"db_id": "Q5RF10"
},
{
"db_name": "UniProt",
"db_id": "Q64405"
},
{
"db_name": "UniProt",
"db_id": "Q704S8"
},
{
"db_name": "UniProt",
"db_id": "Q9M5L6"
},
{
"db_name": "UniProt",
"db_id": "Q9PWF7"
}
]
},
{
"id": "DS.d44.s0.e5",
"type": "protein",
"text": [
"glutathione peroxidase"
],
"offsets": [
[
176,
198
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O32770"
},
{
"db_name": "UniProt",
"db_id": "O59858"
},
{
"db_name": "UniProt",
"db_id": "Q00277"
},
{
"db_name": "UniProt",
"db_id": "Q9CFV1"
}
]
},
{
"id": "DS.d44.s0.e6",
"type": "protein",
"text": [
"glutathione reductase"
],
"offsets": [
[
210,
231
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O15770"
},
{
"db_name": "UniProt",
"db_id": "P06715"
},
{
"db_name": "UniProt",
"db_id": "P11804"
},
{
"db_name": "UniProt",
"db_id": "P23189"
},
{
"db_name": "UniProt",
"db_id": "P41921"
},
{
"db_name": "UniProt",
"db_id": "P43783"
},
{
"db_name": "UniProt",
"db_id": "P48638"
},
{
"db_name": "UniProt",
"db_id": "P48639"
},
{
"db_name": "UniProt",
"db_id": "P70619"
},
{
"db_name": "UniProt",
"db_id": "P78965"
},
{
"db_name": "UniProt",
"db_id": "Q60151"
},
{
"db_name": "UniProt",
"db_id": "Q6BPI1"
},
{
"db_name": "UniProt",
"db_id": "Q6C5H4"
},
{
"db_name": "UniProt",
"db_id": "Q6FRV2"
},
{
"db_name": "UniProt",
"db_id": "Q6HA23"
},
{
"db_name": "UniProt",
"db_id": "Q74ZK4"
},
{
"db_name": "UniProt",
"db_id": "Q873E8"
},
{
"db_name": "UniProt",
"db_id": "Q94655"
}
]
},
{
"id": "DS.d44.s0.e7",
"type": "compound",
"text": [
"glutathione"
],
"offsets": [
[
176,
187
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
},
{
"id": "DS.d44.s0.e8",
"type": "compound",
"text": [
"GSH"
],
"offsets": [
[
271,
274
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "124886"
}
]
}
] | [] | [] | [] |
DS.d45 | 18226951 | [
{
"id": "DS.d45.s0",
"text": [
"Abnormally high CSF 3-OMD occurs frequently for RLS patients indicating either increased l-dopa synthesis, limitations in l-dopa decarboxylation or increased MAT/COMT activity, or some combination of these."
],
"offsets": [
[
0,
206
]
],
"type": ""
}
] | [
{
"id": "DS.d45.s0.e0",
"type": "compound",
"text": [
"l-dopa"
],
"offsets": [
[
89,
95
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6047"
}
]
},
{
"id": "DS.d45.s0.e1",
"type": "compound",
"text": [
"l-dopa"
],
"offsets": [
[
122,
128
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6047"
}
]
},
{
"id": "DS.d45.s0.e2",
"type": "protein",
"text": [
"MAT"
],
"offsets": [
[
158,
161
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O50163"
},
{
"db_name": "UniProt",
"db_id": "O67222"
},
{
"db_name": "UniProt",
"db_id": "O83772"
},
{
"db_name": "UniProt",
"db_id": "P0A817"
},
{
"db_name": "UniProt",
"db_id": "P0A818"
},
{
"db_name": "UniProt",
"db_id": "P0A819"
},
{
"db_name": "UniProt",
"db_id": "P0A820"
},
{
"db_name": "UniProt",
"db_id": "P24752"
},
{
"db_name": "UniProt",
"db_id": "P43762"
},
{
"db_name": "UniProt",
"db_id": "P47293"
},
{
"db_name": "UniProt",
"db_id": "P50307"
},
{
"db_name": "UniProt",
"db_id": "P54419"
},
{
"db_name": "UniProt",
"db_id": "P56460"
},
{
"db_name": "UniProt",
"db_id": "P56878"
},
{
"db_name": "UniProt",
"db_id": "P57486"
},
{
"db_name": "UniProt",
"db_id": "P57897"
},
{
"db_name": "UniProt",
"db_id": "P61945"
},
{
"db_name": "UniProt",
"db_id": "P61946"
},
{
"db_name": "UniProt",
"db_id": "P66764"
},
{
"db_name": "UniProt",
"db_id": "P66765"
},
{
"db_name": "UniProt",
"db_id": "P66766"
},
{
"db_name": "UniProt",
"db_id": "P66767"
},
{
"db_name": "UniProt",
"db_id": "P72871"
},
{
"db_name": "UniProt",
"db_id": "P77899"
},
{
"db_name": "UniProt",
"db_id": "P78003"
},
{
"db_name": "UniProt",
"db_id": "Q1QCH2"
},
{
"db_name": "UniProt",
"db_id": "Q21NJ5"
},
{
"db_name": "UniProt",
"db_id": "Q21RM4"
},
{
"db_name": "UniProt",
"db_id": "Q28UI9"
},
{
"db_name": "UniProt",
"db_id": "Q2A1N2"
},
{
"db_name": "UniProt",
"db_id": "Q2FFV6"
},
{
"db_name": "UniProt",
"db_id": "Q2GBP1"
},
{
"db_name": "UniProt",
"db_id": "Q2IM98"
},
{
"db_name": "UniProt",
"db_id": "Q2IZR2"
},
{
"db_name": "UniProt",
"db_id": "Q2JIN3"
},
{
"db_name": "UniProt",
"db_id": "Q2JV74"
},
{
"db_name": "UniProt",
"db_id": "Q2NRD1"
},
{
"db_name": "UniProt",
"db_id": "Q2NZF1"
},
{
"db_name": "UniProt",
"db_id": "Q2RK28"
},
{
"db_name": "UniProt",
"db_id": "Q2RYY4"
},
{
"db_name": "UniProt",
"db_id": "Q2SLT3"
},
{
"db_name": "UniProt",
"db_id": "Q2SS11"
},
{
"db_name": "UniProt",
"db_id": "Q2T267"
},
{
"db_name": "UniProt",
"db_id": "Q2VYQ2"
},
{
"db_name": "UniProt",
"db_id": "Q2Y5Z1"
},
{
"db_name": "UniProt",
"db_id": "Q2YTK1"
},
{
"db_name": "UniProt",
"db_id": "Q30PN0"
},
{
"db_name": "UniProt",
"db_id": "Q311V1"
},
{
"db_name": "UniProt",
"db_id": "Q31CL7"
},
{
"db_name": "UniProt",
"db_id": "Q31EL0"
},
{
"db_name": "UniProt",
"db_id": "Q31KC6"
},
{
"db_name": "UniProt",
"db_id": "Q31WK4"
},
{
"db_name": "UniProt",
"db_id": "Q32C11"
},
{
"db_name": "UniProt",
"db_id": "Q38YF8"
},
{
"db_name": "UniProt",
"db_id": "Q39BZ1"
},
{
"db_name": "UniProt",
"db_id": "Q39W48"
},
{
"db_name": "UniProt",
"db_id": "Q3A388"
},
{
"db_name": "UniProt",
"db_id": "Q3AFS4"
},
{
"db_name": "UniProt",
"db_id": "Q3AME2"
},
{
"db_name": "UniProt",
"db_id": "Q3AQC3"
},
{
"db_name": "UniProt",
"db_id": "Q3AWE6"
},
{
"db_name": "UniProt",
"db_id": "Q3B531"
},
{
"db_name": "UniProt",
"db_id": "Q3BXB7"
},
{
"db_name": "UniProt",
"db_id": "Q3IDQ1"
},
{
"db_name": "UniProt",
"db_id": "Q3IW86"
},
{
"db_name": "UniProt",
"db_id": "Q3J7R5"
},
{
"db_name": "UniProt",
"db_id": "Q3JX94"
},
{
"db_name": "UniProt",
"db_id": "Q3K1M7"
},
{
"db_name": "UniProt",
"db_id": "Q3K5E8"
},
{
"db_name": "UniProt",
"db_id": "Q3MF32"
},
{
"db_name": "UniProt",
"db_id": "Q3SFY2"
},
{
"db_name": "UniProt",
"db_id": "Q3YXS9"
},
{
"db_name": "UniProt",
"db_id": "Q3Z943"
},
{
"db_name": "UniProt",
"db_id": "Q3ZZN7"
},
{
"db_name": "UniProt",
"db_id": "Q46H57"
},
{
"db_name": "UniProt",
"db_id": "Q476V0"
},
{
"db_name": "UniProt",
"db_id": "Q47JN4"
},
{
"db_name": "UniProt",
"db_id": "Q47R14"
},
{
"db_name": "UniProt",
"db_id": "Q486L6"
},
{
"db_name": "UniProt",
"db_id": "Q48CH3"
},
{
"db_name": "UniProt",
"db_id": "Q48SU7"
},
{
"db_name": "UniProt",
"db_id": "Q493F2"
},
{
"db_name": "UniProt",
"db_id": "Q49YL6"
},
{
"db_name": "UniProt",
"db_id": "Q4A5F4"
},
{
"db_name": "UniProt",
"db_id": "Q4FNN1"
},
{
"db_name": "UniProt",
"db_id": "Q4FTH7"
},
{
"db_name": "UniProt",
"db_id": "Q4JVH7"
},
{
"db_name": "UniProt",
"db_id": "Q4K4I7"
},
{
"db_name": "UniProt",
"db_id": "Q4L7C7"
},
{
"db_name": "UniProt",
"db_id": "Q4QLC5"
},
{
"db_name": "UniProt",
"db_id": "Q4UR08"
},
{
"db_name": "UniProt",
"db_id": "Q4ZM01"
},
{
"db_name": "UniProt",
"db_id": "Q57K26"
},
{
"db_name": "UniProt",
"db_id": "Q5E7R2"
},
{
"db_name": "UniProt",
"db_id": "Q5FAC0"
},
{
"db_name": "UniProt",
"db_id": "Q5FIN8"
},
{
"db_name": "UniProt",
"db_id": "Q5FSK6"
},
{
"db_name": "UniProt",
"db_id": "Q5GW76"
},
{
"db_name": "UniProt",
"db_id": "Q5HEY9"
},
{
"db_name": "UniProt",
"db_id": "Q5HNB8"
},
{
"db_name": "UniProt",
"db_id": "Q5KW02"
},
{
"db_name": "UniProt",
"db_id": "Q5LJ26"
},
{
"db_name": "UniProt",
"db_id": "Q5LLL2"
},
{
"db_name": "UniProt",
"db_id": "Q5LZI0"
},
{
"db_name": "UniProt",
"db_id": "Q5M434"
},
{
"db_name": "UniProt",
"db_id": "Q5N1I9"
},
{
"db_name": "UniProt",
"db_id": "Q5NIC7"
},
{
"db_name": "UniProt",
"db_id": "Q5NQV7"
},
{
"db_name": "UniProt",
"db_id": "Q5P2V5"
},
{
"db_name": "UniProt",
"db_id": "Q5PJJ2"
},
{
"db_name": "UniProt",
"db_id": "Q5QVM7"
},
{
"db_name": "UniProt",
"db_id": "Q5SHT8"
},
{
"db_name": "UniProt",
"db_id": "Q5WDZ8"
},
{
"db_name": "UniProt",
"db_id": "Q5WV18"
},
{
"db_name": "UniProt",
"db_id": "Q5X3N0"
},
{
"db_name": "UniProt",
"db_id": "Q5XBJ6"
},
{
"db_name": "UniProt",
"db_id": "Q5YTN0"
},
{
"db_name": "UniProt",
"db_id": "Q5ZTY6"
},
{
"db_name": "UniProt",
"db_id": "Q60CG7"
},
{
"db_name": "UniProt",
"db_id": "Q62EZ1"
},
{
"db_name": "UniProt",
"db_id": "Q632S5"
},
{
"db_name": "UniProt",
"db_id": "Q63YH5"
},
{
"db_name": "UniProt",
"db_id": "Q650L4"
},
{
"db_name": "UniProt",
"db_id": "Q65FV8"
},
{
"db_name": "UniProt",
"db_id": "Q65UT4"
},
{
"db_name": "UniProt",
"db_id": "Q661P3"
},
{
"db_name": "UniProt",
"db_id": "Q666P5"
},
{
"db_name": "UniProt",
"db_id": "Q67T90"
},
{
"db_name": "UniProt",
"db_id": "Q6A8H3"
},
{
"db_name": "UniProt",
"db_id": "Q6AF79"
},
{
"db_name": "UniProt",
"db_id": "Q6AQ43"
},
{
"db_name": "UniProt",
"db_id": "Q6D081"
},
{
"db_name": "UniProt",
"db_id": "Q6F1M6"
},
{
"db_name": "UniProt",
"db_id": "Q6FAQ6"
},
{
"db_name": "UniProt",
"db_id": "Q6G8E3"
},
{
"db_name": "UniProt",
"db_id": "Q6GFR6"
},
{
"db_name": "UniProt",
"db_id": "Q6HCB4"
},
{
"db_name": "UniProt",
"db_id": "Q6LMM8"
},
{
"db_name": "UniProt",
"db_id": "Q6MPK2"
},
{
"db_name": "UniProt",
"db_id": "Q6MTB6"
},
{
"db_name": "UniProt",
"db_id": "Q71Z03"
},
{
"db_name": "UniProt",
"db_id": "Q729A3"
},
{
"db_name": "UniProt",
"db_id": "Q72I53"
},
{
"db_name": "UniProt",
"db_id": "Q72SM5"
},
{
"db_name": "UniProt",
"db_id": "Q72YV6"
},
{
"db_name": "UniProt",
"db_id": "Q73JR4"
},
{
"db_name": "UniProt",
"db_id": "Q741G5"
},
{
"db_name": "UniProt",
"db_id": "Q74KS4"
},
{
"db_name": "UniProt",
"db_id": "Q7M7Z2"
},
{
"db_name": "UniProt",
"db_id": "Q7MHK6"
},
{
"db_name": "UniProt",
"db_id": "Q7MTQ0"
},
{
"db_name": "UniProt",
"db_id": "Q7N119"
},
{
"db_name": "UniProt",
"db_id": "Q7NHG0"
},
{
"db_name": "UniProt",
"db_id": "Q7NZF9"
},
{
"db_name": "UniProt",
"db_id": "Q7U051"
},
{
"db_name": "UniProt",
"db_id": "Q7U4S6"
},
{
"db_name": "UniProt",
"db_id": "Q7URU7"
},
{
"db_name": "UniProt",
"db_id": "Q7V2Y8"
},
{
"db_name": "UniProt",
"db_id": "Q7V5A2"
},
{
"db_name": "UniProt",
"db_id": "Q7VDM7"
},
{
"db_name": "UniProt",
"db_id": "Q7VFY5"
},
{
"db_name": "UniProt",
"db_id": "Q7VNG7"
},
{
"db_name": "UniProt",
"db_id": "Q7VRG5"
},
{
"db_name": "UniProt",
"db_id": "Q7VUL5"
},
{
"db_name": "UniProt",
"db_id": "Q7W200"
},
{
"db_name": "UniProt",
"db_id": "Q7WQX8"
},
{
"db_name": "UniProt",
"db_id": "Q7WYG5"
},
{
"db_name": "UniProt",
"db_id": "Q7WYN1"
},
{
"db_name": "UniProt",
"db_id": "Q816Q8"
},
{
"db_name": "UniProt",
"db_id": "Q81KI0"
},
{
"db_name": "UniProt",
"db_id": "Q827Q0"
},
{
"db_name": "UniProt",
"db_id": "Q82WL2"
},
{
"db_name": "UniProt",
"db_id": "Q837P9"
},
{
"db_name": "UniProt",
"db_id": "Q83A78"
},
{
"db_name": "UniProt",
"db_id": "Q83GE4"
},
{
"db_name": "UniProt",
"db_id": "Q83HT7"
},
{
"db_name": "UniProt",
"db_id": "Q84FD3"
},
{
"db_name": "UniProt",
"db_id": "Q87AY6"
},
{
"db_name": "UniProt",
"db_id": "Q87LK6"
},
{
"db_name": "UniProt",
"db_id": "Q88AK7"
},
{
"db_name": "UniProt",
"db_id": "Q88D60"
},
{
"db_name": "UniProt",
"db_id": "Q88XB8"
},
{
"db_name": "UniProt",
"db_id": "Q898W7"
},
{
"db_name": "UniProt",
"db_id": "Q89HP5"
},
{
"db_name": "UniProt",
"db_id": "Q8A2T6"
},
{
"db_name": "UniProt",
"db_id": "Q8CNT5"
},
{
"db_name": "UniProt",
"db_id": "Q8CXS7"
},
{
"db_name": "UniProt",
"db_id": "Q8D2N8"
},
{
"db_name": "UniProt",
"db_id": "Q8DCA3"
},
{
"db_name": "UniProt",
"db_id": "Q8DK88"
},
{
"db_name": "UniProt",
"db_id": "Q8DQH0"
},
{
"db_name": "UniProt",
"db_id": "Q8DT23"
},
{
"db_name": "UniProt",
"db_id": "Q8E0A3"
},
{
"db_name": "UniProt",
"db_id": "Q8E5Y0"
},
{
"db_name": "UniProt",
"db_id": "Q8EIB4"
},
{
"db_name": "UniProt",
"db_id": "Q8EP05"
},
{
"db_name": "UniProt",
"db_id": "Q8FT48"
},
{
"db_name": "UniProt",
"db_id": "Q8G3H4"
},
{
"db_name": "UniProt",
"db_id": "Q8K715"
},
{
"db_name": "UniProt",
"db_id": "Q8K9E5"
},
{
"db_name": "UniProt",
"db_id": "Q8KEG7"
},
{
"db_name": "UniProt",
"db_id": "Q8NVZ9"
},
{
"db_name": "UniProt",
"db_id": "Q8P0G6"
},
{
"db_name": "UniProt",
"db_id": "Q8PCH3"
},
{
"db_name": "UniProt",
"db_id": "Q8PP75"
},
{
"db_name": "UniProt",
"db_id": "Q8RCE4"
},
{
"db_name": "UniProt",
"db_id": "Q8RGE5"
},
{
"db_name": "UniProt",
"db_id": "Q8Y347"
},
{
"db_name": "UniProt",
"db_id": "Q8Y6M0"
},
{
"db_name": "UniProt",
"db_id": "Q8ZHG7"
},
{
"db_name": "UniProt",
"db_id": "Q92AZ5"
},
{
"db_name": "UniProt",
"db_id": "Q938W7"
},
{
"db_name": "UniProt",
"db_id": "Q97F85"
},
{
"db_name": "UniProt",
"db_id": "Q97RN9"
},
{
"db_name": "UniProt",
"db_id": "Q98A80"
},
{
"db_name": "UniProt",
"db_id": "Q98PM0"
},
{
"db_name": "UniProt",
"db_id": "Q99Z77"
},
{
"db_name": "UniProt",
"db_id": "Q9CCQ4"
},
{
"db_name": "UniProt",
"db_id": "Q9CEE0"
},
{
"db_name": "UniProt",
"db_id": "Q9I5Z0"
},
{
"db_name": "UniProt",
"db_id": "Q9JVV6"
},
{
"db_name": "UniProt",
"db_id": "Q9JY09"
},
{
"db_name": "UniProt",
"db_id": "Q9K5E4"
},
{
"db_name": "UniProt",
"db_id": "Q9K7Q9"
},
{
"db_name": "UniProt",
"db_id": "Q9KUP3"
},
{
"db_name": "UniProt",
"db_id": "Q9L0Y3"
},
{
"db_name": "UniProt",
"db_id": "Q9PGB0"
},
{
"db_name": "UniProt",
"db_id": "Q9RL99"
},
{
"db_name": "UniProt",
"db_id": "Q9RWM6"
},
{
"db_name": "UniProt",
"db_id": "Q9X1Y8"
},
{
"db_name": "UniProt",
"db_id": "Q9X4Q2"
},
{
"db_name": "UniProt",
"db_id": "Q9ZMN5"
}
]
},
{
"id": "DS.d45.s0.e3",
"type": "protein",
"text": [
"COMT"
],
"offsets": [
[
162,
166
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O23760"
},
{
"db_name": "UniProt",
"db_id": "O81646"
},
{
"db_name": "UniProt",
"db_id": "O82054"
},
{
"db_name": "UniProt",
"db_id": "P21964"
},
{
"db_name": "UniProt",
"db_id": "P28002"
},
{
"db_name": "UniProt",
"db_id": "P46484"
},
{
"db_name": "UniProt",
"db_id": "Q06509"
},
{
"db_name": "UniProt",
"db_id": "Q06528"
},
{
"db_name": "UniProt",
"db_id": "Q43239"
},
{
"db_name": "UniProt",
"db_id": "Q43609"
},
{
"db_name": "UniProt",
"db_id": "Q6ZD89"
},
{
"db_name": "UniProt",
"db_id": "Q8GU25"
},
{
"db_name": "UniProt",
"db_id": "Q8LL87"
},
{
"db_name": "UniProt",
"db_id": "Q8W013"
},
{
"db_name": "UniProt",
"db_id": "Q99028"
},
{
"db_name": "UniProt",
"db_id": "Q9FQY8"
},
{
"db_name": "UniProt",
"db_id": "Q9SWC2"
}
]
}
] | [] | [] | [] |
DS.d46 | 18227836 | [
{
"id": "DS.d46.s0",
"text": [
"To test this hypothesis, we investigated whether disruption of the oxytocin gene (Oxt-/-) made mice more susceptible to the psychosis-related effects of amphetamine (Amp), apomorphine (Apo) and phencyclidine (PCP)."
],
"offsets": [
[
0,
214
]
],
"type": ""
}
] | [
{
"id": "DS.d46.s0.e0",
"type": "protein",
"text": [
"oxytocin"
],
"offsets": [
[
67,
75
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01175"
},
{
"db_name": "UniProt",
"db_id": "P01176"
},
{
"db_name": "UniProt",
"db_id": "P01177"
},
{
"db_name": "UniProt",
"db_id": "P01178"
},
{
"db_name": "UniProt",
"db_id": "P01179"
},
{
"db_name": "UniProt",
"db_id": "P13389"
},
{
"db_name": "UniProt",
"db_id": "P32005"
},
{
"db_name": "UniProt",
"db_id": "P35454"
},
{
"db_name": "UniProt",
"db_id": "P69043"
},
{
"db_name": "UniProt",
"db_id": "P69044"
},
{
"db_name": "UniProt",
"db_id": "P69056"
},
{
"db_name": "UniProt",
"db_id": "P69057"
},
{
"db_name": "UniProt",
"db_id": "P69058"
}
]
},
{
"id": "DS.d46.s0.e1",
"type": "protein",
"text": [
"Oxt"
],
"offsets": [
[
82,
85
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01179"
},
{
"db_name": "UniProt",
"db_id": "P35454"
},
{
"db_name": "UniProt",
"db_id": "Q5QQ53"
},
{
"db_name": "UniProt",
"db_id": "Q7KVA1"
}
]
},
{
"id": "DS.d46.s0.e2",
"type": "compound",
"text": [
"amphetamine"
],
"offsets": [
[
153,
164
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3007"
},
{
"db_name": "PubChem",
"db_id": "5826"
},
{
"db_name": "PubChem",
"db_id": "32893"
}
]
},
{
"id": "DS.d46.s0.e3",
"type": "compound",
"text": [
"Amp"
],
"offsets": [
[
166,
169
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6083"
}
]
},
{
"id": "DS.d46.s0.e4",
"type": "compound",
"text": [
"apomorphine"
],
"offsets": [
[
172,
183
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6005"
}
]
},
{
"id": "DS.d46.s0.e5",
"type": "compound",
"text": [
"phencyclidine"
],
"offsets": [
[
194,
207
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6468"
}
]
}
] | [] | [] | [] |
DS.d47 | 18227838 | [
{
"id": "DS.d47.s0",
"text": [
"The mood stabilizers lithium and valproate activate the ERK pathway in prefrontal cortex and hippocampus and potentiate ERK pathway-mediated neurite growth, neuronal survival and hippocampal neurogenesis."
],
"offsets": [
[
0,
204
]
],
"type": ""
}
] | [
{
"id": "DS.d47.s0.e0",
"type": "compound",
"text": [
"lithium"
],
"offsets": [
[
21,
28
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "28486"
},
{
"db_name": "PubChem",
"db_id": "3028194"
}
]
},
{
"id": "DS.d47.s0.e1",
"type": "compound",
"text": [
"valproate"
],
"offsets": [
[
33,
42
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "3121"
}
]
},
{
"id": "DS.d47.s0.e2",
"type": "protein",
"text": [
"ERK"
],
"offsets": [
[
56,
59
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P29323"
}
]
},
{
"id": "DS.d47.s0.e3",
"type": "protein",
"text": [
"ERK"
],
"offsets": [
[
120,
123
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P29323"
}
]
}
] | [] | [] | [
{
"id": "DS.d47.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d47.s0.e0",
"arg2_id": "DS.d47.s0.e2",
"normalized": []
},
{
"id": "DS.d47.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d47.s0.e1",
"arg2_id": "DS.d47.s0.e2",
"normalized": []
}
] |
DS.d48 | 18227970 | [
{
"id": "DS.d48.s0",
"text": [
"In the root soluble fraction, the suicide inhibitor alpha-difluoromethyl-lysine suppressed the activity of lysine decarboxylase and of ornithine decarboxylase to the same extent, but had no effect on arginine decarboxylase activity."
],
"offsets": [
[
0,
232
]
],
"type": ""
}
] | [
{
"id": "DS.d48.s0.e0",
"type": "compound",
"text": [
"difluoromethyl"
],
"offsets": [
[
58,
72
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "137670"
}
]
},
{
"id": "DS.d48.s0.e1",
"type": "compound",
"text": [
"lysine"
],
"offsets": [
[
73,
79
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "866"
},
{
"db_name": "PubChem",
"db_id": "5962"
}
]
},
{
"id": "DS.d48.s0.e2",
"type": "protein",
"text": [
"lysine decarboxylase"
],
"offsets": [
[
107,
127
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05033"
}
]
},
{
"id": "DS.d48.s0.e3",
"type": "protein",
"text": [
"ornithine decarboxylase"
],
"offsets": [
[
135,
158
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O22616"
},
{
"db_name": "UniProt",
"db_id": "P00860"
},
{
"db_name": "UniProt",
"db_id": "P07805"
},
{
"db_name": "UniProt",
"db_id": "P08432"
},
{
"db_name": "UniProt",
"db_id": "P09057"
},
{
"db_name": "UniProt",
"db_id": "P11926"
},
{
"db_name": "UniProt",
"db_id": "P14019"
},
{
"db_name": "UniProt",
"db_id": "P27116"
},
{
"db_name": "UniProt",
"db_id": "P27117"
},
{
"db_name": "UniProt",
"db_id": "P27118"
},
{
"db_name": "UniProt",
"db_id": "P27119"
},
{
"db_name": "UniProt",
"db_id": "P27121"
},
{
"db_name": "UniProt",
"db_id": "P41931"
},
{
"db_name": "UniProt",
"db_id": "P44317"
},
{
"db_name": "UniProt",
"db_id": "P49725"
},
{
"db_name": "UniProt",
"db_id": "P50134"
},
{
"db_name": "UniProt",
"db_id": "P78599"
},
{
"db_name": "UniProt",
"db_id": "Q8S3N2"
},
{
"db_name": "UniProt",
"db_id": "Q92445"
},
{
"db_name": "UniProt",
"db_id": "Q9UQW9"
}
]
},
{
"id": "DS.d48.s0.e4",
"type": "protein",
"text": [
"arginine decarboxylase"
],
"offsets": [
[
200,
222
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O81160"
},
{
"db_name": "UniProt",
"db_id": "O82475"
},
{
"db_name": "UniProt",
"db_id": "P21885"
},
{
"db_name": "UniProt",
"db_id": "P22220"
},
{
"db_name": "UniProt",
"db_id": "P49726"
},
{
"db_name": "UniProt",
"db_id": "Q39827"
},
{
"db_name": "UniProt",
"db_id": "Q43075"
},
{
"db_name": "UniProt",
"db_id": "Q819L4"
},
{
"db_name": "UniProt",
"db_id": "Q81MS2"
},
{
"db_name": "UniProt",
"db_id": "Q96412"
},
{
"db_name": "UniProt",
"db_id": "Q96A70"
},
{
"db_name": "UniProt",
"db_id": "Q9K9K5"
},
{
"db_name": "UniProt",
"db_id": "Q9SNN0"
}
]
}
] | [] | [] | [
{
"id": "DS.d48.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d48.s0.e0",
"arg2_id": "DS.d48.s0.e3",
"normalized": []
},
{
"id": "DS.d48.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d48.s0.e1",
"arg2_id": "DS.d48.s0.e3",
"normalized": []
},
{
"id": "DS.d48.s0.i4",
"type": "compound-protein-interaction",
"arg1_id": "DS.d48.s0.e0",
"arg2_id": "DS.d48.s0.e2",
"normalized": []
},
{
"id": "DS.d48.s0.i5",
"type": "compound-protein-interaction",
"arg1_id": "DS.d48.s0.e1",
"arg2_id": "DS.d48.s0.e2",
"normalized": []
}
] |
DS.d49 | 18228136 | [
{
"id": "DS.d49.s0",
"text": [
"RT(2) Profiler PCR Array was used to identify differentially expressed genes in Dox and/or 2ME treatment groups, based on significance of results 4 genes were selected: MDR1, Bcl2, P53 and Cyclin D1."
],
"offsets": [
[
0,
199
]
],
"type": ""
},
{
"id": "DS.d49.s1",
"text": [
"The array and western blotting showed that Bcl2 and Cyclin D1 expression were down regulated; P53 expression was not affected while MDR1 was over expressed by combination of 2ME with Dox."
],
"offsets": [
[
200,
387
]
],
"type": ""
},
{
"id": "DS.d49.s2",
"text": [
"In conclusion, 2ME chemosensitizes resistant breast cancer cells to Dox cytotoxicity by down regulating expression of Bcl2 and Cyclin D1, augmenting caspase 3 activity as well as inducing cell cycle block in G(1) and S phases."
],
"offsets": [
[
388,
614
]
],
"type": ""
}
] | [
{
"id": "DS.d49.s0.e0",
"type": "compound",
"text": [
"2ME"
],
"offsets": [
[
91,
94
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "10903"
}
]
},
{
"id": "DS.d49.s0.e1",
"type": "protein",
"text": [
"MDR1"
],
"offsets": [
[
169,
173
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P08183"
},
{
"db_name": "UniProt",
"db_id": "P13568"
},
{
"db_name": "UniProt",
"db_id": "P16875"
},
{
"db_name": "UniProt",
"db_id": "P28873"
},
{
"db_name": "UniProt",
"db_id": "P53258"
},
{
"db_name": "UniProt",
"db_id": "Q06034"
},
{
"db_name": "UniProt",
"db_id": "Q9LJX0"
},
{
"db_name": "UniProt",
"db_id": "Q9ZR72"
}
]
},
{
"id": "DS.d49.s0.e2",
"type": "protein",
"text": [
"Bcl2"
],
"offsets": [
[
175,
179
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10417"
},
{
"db_name": "UniProt",
"db_id": "P49950"
}
]
},
{
"id": "DS.d49.s0.e3",
"type": "protein",
"text": [
"P53"
],
"offsets": [
[
181,
184
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O09185"
},
{
"db_name": "UniProt",
"db_id": "O12946"
},
{
"db_name": "UniProt",
"db_id": "O57538"
},
{
"db_name": "UniProt",
"db_id": "O93379"
},
{
"db_name": "UniProt",
"db_id": "P02340"
},
{
"db_name": "UniProt",
"db_id": "P04637"
},
{
"db_name": "UniProt",
"db_id": "P10361"
},
{
"db_name": "UniProt",
"db_id": "P19558"
},
{
"db_name": "UniProt",
"db_id": "P19559"
},
{
"db_name": "UniProt",
"db_id": "P56423"
},
{
"db_name": "UniProt",
"db_id": "P56424"
},
{
"db_name": "UniProt",
"db_id": "P61260"
},
{
"db_name": "UniProt",
"db_id": "P79820"
},
{
"db_name": "UniProt",
"db_id": "P79892"
},
{
"db_name": "UniProt",
"db_id": "Q29537"
},
{
"db_name": "UniProt",
"db_id": "Q42578"
},
{
"db_name": "UniProt",
"db_id": "Q8SPZ3"
},
{
"db_name": "UniProt",
"db_id": "Q92143"
},
{
"db_name": "UniProt",
"db_id": "Q9TTA1"
},
{
"db_name": "UniProt",
"db_id": "Q9TUB2"
},
{
"db_name": "UniProt",
"db_id": "Q9W678"
},
{
"db_name": "UniProt",
"db_id": "Q9W679"
}
]
},
{
"id": "DS.d49.s0.e4",
"type": "protein",
"text": [
"Cyclin"
],
"offsets": [
[
189,
195
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O01377"
},
{
"db_name": "UniProt",
"db_id": "O16852"
},
{
"db_name": "UniProt",
"db_id": "P04961"
},
{
"db_name": "UniProt",
"db_id": "P12004"
},
{
"db_name": "UniProt",
"db_id": "P17070"
},
{
"db_name": "UniProt",
"db_id": "P17917"
},
{
"db_name": "UniProt",
"db_id": "P17918"
},
{
"db_name": "UniProt",
"db_id": "P18248"
},
{
"db_name": "UniProt",
"db_id": "P22177"
},
{
"db_name": "UniProt",
"db_id": "P24314"
},
{
"db_name": "UniProt",
"db_id": "P31008"
},
{
"db_name": "UniProt",
"db_id": "P53358"
},
{
"db_name": "UniProt",
"db_id": "P61074"
},
{
"db_name": "UniProt",
"db_id": "Q00265"
},
{
"db_name": "UniProt",
"db_id": "Q00268"
}
]
},
{
"id": "DS.d49.s1.e0",
"type": "protein",
"text": [
"Bcl2"
],
"offsets": [
[
243,
247
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10417"
},
{
"db_name": "UniProt",
"db_id": "P49950"
}
]
},
{
"id": "DS.d49.s1.e1",
"type": "protein",
"text": [
"Cyclin"
],
"offsets": [
[
252,
258
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O01377"
},
{
"db_name": "UniProt",
"db_id": "O16852"
},
{
"db_name": "UniProt",
"db_id": "P04961"
},
{
"db_name": "UniProt",
"db_id": "P12004"
},
{
"db_name": "UniProt",
"db_id": "P17070"
},
{
"db_name": "UniProt",
"db_id": "P17917"
},
{
"db_name": "UniProt",
"db_id": "P17918"
},
{
"db_name": "UniProt",
"db_id": "P18248"
},
{
"db_name": "UniProt",
"db_id": "P22177"
},
{
"db_name": "UniProt",
"db_id": "P24314"
},
{
"db_name": "UniProt",
"db_id": "P31008"
},
{
"db_name": "UniProt",
"db_id": "P53358"
},
{
"db_name": "UniProt",
"db_id": "P61074"
},
{
"db_name": "UniProt",
"db_id": "Q00265"
},
{
"db_name": "UniProt",
"db_id": "Q00268"
}
]
},
{
"id": "DS.d49.s1.e2",
"type": "protein",
"text": [
"P53"
],
"offsets": [
[
294,
297
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O09185"
},
{
"db_name": "UniProt",
"db_id": "O12946"
},
{
"db_name": "UniProt",
"db_id": "O57538"
},
{
"db_name": "UniProt",
"db_id": "O93379"
},
{
"db_name": "UniProt",
"db_id": "P02340"
},
{
"db_name": "UniProt",
"db_id": "P04637"
},
{
"db_name": "UniProt",
"db_id": "P10361"
},
{
"db_name": "UniProt",
"db_id": "P19558"
},
{
"db_name": "UniProt",
"db_id": "P19559"
},
{
"db_name": "UniProt",
"db_id": "P56423"
},
{
"db_name": "UniProt",
"db_id": "P56424"
},
{
"db_name": "UniProt",
"db_id": "P61260"
},
{
"db_name": "UniProt",
"db_id": "P79820"
},
{
"db_name": "UniProt",
"db_id": "P79892"
},
{
"db_name": "UniProt",
"db_id": "Q29537"
},
{
"db_name": "UniProt",
"db_id": "Q42578"
},
{
"db_name": "UniProt",
"db_id": "Q8SPZ3"
},
{
"db_name": "UniProt",
"db_id": "Q92143"
},
{
"db_name": "UniProt",
"db_id": "Q9TTA1"
},
{
"db_name": "UniProt",
"db_id": "Q9TUB2"
},
{
"db_name": "UniProt",
"db_id": "Q9W678"
},
{
"db_name": "UniProt",
"db_id": "Q9W679"
}
]
},
{
"id": "DS.d49.s1.e3",
"type": "protein",
"text": [
"MDR1"
],
"offsets": [
[
332,
336
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P08183"
},
{
"db_name": "UniProt",
"db_id": "P13568"
},
{
"db_name": "UniProt",
"db_id": "P16875"
},
{
"db_name": "UniProt",
"db_id": "P28873"
},
{
"db_name": "UniProt",
"db_id": "P53258"
},
{
"db_name": "UniProt",
"db_id": "Q06034"
},
{
"db_name": "UniProt",
"db_id": "Q9LJX0"
},
{
"db_name": "UniProt",
"db_id": "Q9ZR72"
}
]
},
{
"id": "DS.d49.s1.e4",
"type": "compound",
"text": [
"2ME"
],
"offsets": [
[
374,
377
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "10903"
}
]
},
{
"id": "DS.d49.s2.e0",
"type": "compound",
"text": [
"2ME"
],
"offsets": [
[
403,
406
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "10903"
}
]
},
{
"id": "DS.d49.s2.e1",
"type": "protein",
"text": [
"Bcl2"
],
"offsets": [
[
506,
510
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10417"
},
{
"db_name": "UniProt",
"db_id": "P49950"
}
]
},
{
"id": "DS.d49.s2.e2",
"type": "protein",
"text": [
"Cyclin"
],
"offsets": [
[
515,
521
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O01377"
},
{
"db_name": "UniProt",
"db_id": "O16852"
},
{
"db_name": "UniProt",
"db_id": "P04961"
},
{
"db_name": "UniProt",
"db_id": "P12004"
},
{
"db_name": "UniProt",
"db_id": "P17070"
},
{
"db_name": "UniProt",
"db_id": "P17917"
},
{
"db_name": "UniProt",
"db_id": "P17918"
},
{
"db_name": "UniProt",
"db_id": "P18248"
},
{
"db_name": "UniProt",
"db_id": "P22177"
},
{
"db_name": "UniProt",
"db_id": "P24314"
},
{
"db_name": "UniProt",
"db_id": "P31008"
},
{
"db_name": "UniProt",
"db_id": "P53358"
},
{
"db_name": "UniProt",
"db_id": "P61074"
},
{
"db_name": "UniProt",
"db_id": "Q00265"
},
{
"db_name": "UniProt",
"db_id": "Q00268"
}
]
}
] | [] | [] | [
{
"id": "DS.d49.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s0.e0",
"arg2_id": "DS.d49.s0.e4",
"normalized": []
},
{
"id": "DS.d49.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s0.e0",
"arg2_id": "DS.d49.s0.e3",
"normalized": []
},
{
"id": "DS.d49.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s0.e0",
"arg2_id": "DS.d49.s0.e1",
"normalized": []
},
{
"id": "DS.d49.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s0.e0",
"arg2_id": "DS.d49.s0.e2",
"normalized": []
},
{
"id": "DS.d49.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s1.e4",
"arg2_id": "DS.d49.s1.e1",
"normalized": []
},
{
"id": "DS.d49.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s1.e4",
"arg2_id": "DS.d49.s1.e3",
"normalized": []
},
{
"id": "DS.d49.s1.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s1.e4",
"arg2_id": "DS.d49.s1.e0",
"normalized": []
},
{
"id": "DS.d49.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s2.e0",
"arg2_id": "DS.d49.s2.e2",
"normalized": []
},
{
"id": "DS.d49.s2.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d49.s2.e0",
"arg2_id": "DS.d49.s2.e1",
"normalized": []
}
] |
DS.d50 | 18230627 | [
{
"id": "DS.d50.s0",
"text": [
"Randomised trials have demonstrated that the efficacy of anti-tumour necrosis factor (TNF) agents is significantly increased by concomitant methotrexate (MTX) in rheumatoid arthritis (RA)."
],
"offsets": [
[
0,
188
]
],
"type": ""
}
] | [
{
"id": "DS.d50.s0.e0",
"type": "protein",
"text": [
"TNF"
],
"offsets": [
[
86,
89
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35734"
},
{
"db_name": "UniProt",
"db_id": "O77510"
},
{
"db_name": "UniProt",
"db_id": "O77764"
},
{
"db_name": "UniProt",
"db_id": "P01375"
},
{
"db_name": "UniProt",
"db_id": "P04924"
},
{
"db_name": "UniProt",
"db_id": "P13296"
},
{
"db_name": "UniProt",
"db_id": "P19101"
},
{
"db_name": "UniProt",
"db_id": "P23383"
},
{
"db_name": "UniProt",
"db_id": "P23563"
},
{
"db_name": "UniProt",
"db_id": "P29553"
},
{
"db_name": "UniProt",
"db_id": "P33620"
},
{
"db_name": "UniProt",
"db_id": "P36939"
},
{
"db_name": "UniProt",
"db_id": "P48094"
},
{
"db_name": "UniProt",
"db_id": "P51435"
},
{
"db_name": "UniProt",
"db_id": "P51742"
},
{
"db_name": "UniProt",
"db_id": "P51743"
},
{
"db_name": "UniProt",
"db_id": "P59684"
},
{
"db_name": "UniProt",
"db_id": "P59693"
},
{
"db_name": "UniProt",
"db_id": "P59694"
},
{
"db_name": "UniProt",
"db_id": "P59695"
},
{
"db_name": "UniProt",
"db_id": "P79337"
},
{
"db_name": "UniProt",
"db_id": "P79374"
},
{
"db_name": "UniProt",
"db_id": "Q06599"
},
{
"db_name": "UniProt",
"db_id": "Q19LH4"
},
{
"db_name": "UniProt",
"db_id": "Q1G1A2"
},
{
"db_name": "UniProt",
"db_id": "Q1WM27"
},
{
"db_name": "UniProt",
"db_id": "Q2MH05"
},
{
"db_name": "UniProt",
"db_id": "Q539C2"
},
{
"db_name": "UniProt",
"db_id": "Q75N23"
},
{
"db_name": "UniProt",
"db_id": "Q8HZD9"
},
{
"db_name": "UniProt",
"db_id": "Q8JFG3"
},
{
"db_name": "UniProt",
"db_id": "Q8MKG8"
},
{
"db_name": "UniProt",
"db_id": "Q8WNR1"
},
{
"db_name": "UniProt",
"db_id": "Q9BEA1"
}
]
},
{
"id": "DS.d50.s0.e1",
"type": "compound",
"text": [
"methotrexate"
],
"offsets": [
[
140,
152
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "126941"
}
]
}
] | [] | [] | [
{
"id": "DS.d50.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d50.s0.e1",
"arg2_id": "DS.d50.s0.e0",
"normalized": []
}
] |
DS.d51 | 18243311 | [
{
"id": "DS.d51.s0",
"text": [
"Neither apyrase nor ATP altered production of reactive oxygen intermediates (ROI) or reactive nitrogen intermediates (RNI) by bovine monocytes."
],
"offsets": [
[
0,
143
]
],
"type": ""
}
] | [
{
"id": "DS.d51.s0.e0",
"type": "protein",
"text": [
"apyrase"
],
"offsets": [
[
8,
15
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P52914"
}
]
},
{
"id": "DS.d51.s0.e1",
"type": "compound",
"text": [
"ATP"
],
"offsets": [
[
20,
23
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5957"
}
]
},
{
"id": "DS.d51.s0.e2",
"type": "compound",
"text": [
"oxygen"
],
"offsets": [
[
55,
61
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "977"
}
]
},
{
"id": "DS.d51.s0.e3",
"type": "compound",
"text": [
"nitrogen"
],
"offsets": [
[
94,
102
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "947"
},
{
"db_name": "PubChem",
"db_id": "123329"
}
]
}
] | [] | [] | [] |
DS.d52 | 18243368 | [
{
"id": "DS.d52.s0",
"text": [
"In this systematic review, we have analyzed the results of 52 clinical trials, including 72 intervention groups and 6290 patients, on vitamin D supplementation in order to evaluate the experimental evidence and the effects of age and chronic immobility on responses of parathyroid hormone (PTH)."
],
"offsets": [
[
0,
295
]
],
"type": ""
},
{
"id": "DS.d52.s1",
"text": [
"The vitamin D supplementation of the chronically immobile patients resulted in a smaller decrease in PTH 0.001)."
],
"offsets": [
[
296,
408
]
],
"type": ""
},
{
"id": "DS.d52.s2",
"text": [
"Our results also suggest that PTH decreases quite linearly during vitamin D supplementation at any given 25-OHD level."
],
"offsets": [
[
409,
527
]
],
"type": ""
}
] | [
{
"id": "DS.d52.s0.e0",
"type": "compound",
"text": [
"vitamin D"
],
"offsets": [
[
134,
143
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5280795"
}
]
},
{
"id": "DS.d52.s0.e1",
"type": "protein",
"text": [
"PTH"
],
"offsets": [
[
290,
293
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O27732"
},
{
"db_name": "UniProt",
"db_id": "O28185"
},
{
"db_name": "UniProt",
"db_id": "O66677"
},
{
"db_name": "UniProt",
"db_id": "O74017"
},
{
"db_name": "UniProt",
"db_id": "O74806"
},
{
"db_name": "UniProt",
"db_id": "O83975"
},
{
"db_name": "UniProt",
"db_id": "O84806"
},
{
"db_name": "UniProt",
"db_id": "O85235"
},
{
"db_name": "UniProt",
"db_id": "P01268"
},
{
"db_name": "UniProt",
"db_id": "P01269"
},
{
"db_name": "UniProt",
"db_id": "P01270"
},
{
"db_name": "UniProt",
"db_id": "P04089"
},
{
"db_name": "UniProt",
"db_id": "P0A281"
},
{
"db_name": "UniProt",
"db_id": "P0A282"
},
{
"db_name": "UniProt",
"db_id": "P0A7D1"
},
{
"db_name": "UniProt",
"db_id": "P0A7D2"
},
{
"db_name": "UniProt",
"db_id": "P0A7D3"
},
{
"db_name": "UniProt",
"db_id": "P15743"
},
{
"db_name": "UniProt",
"db_id": "P37470"
},
{
"db_name": "UniProt",
"db_id": "P38876"
},
{
"db_name": "UniProt",
"db_id": "P44682"
},
{
"db_name": "UniProt",
"db_id": "P47329"
},
{
"db_name": "UniProt",
"db_id": "P47714"
},
{
"db_name": "UniProt",
"db_id": "P49607"
},
{
"db_name": "UniProt",
"db_id": "P52212"
},
{
"db_name": "UniProt",
"db_id": "P56077"
},
{
"db_name": "UniProt",
"db_id": "P57287"
},
{
"db_name": "UniProt",
"db_id": "P57820"
},
{
"db_name": "UniProt",
"db_id": "P59490"
},
{
"db_name": "UniProt",
"db_id": "P61234"
},
{
"db_name": "UniProt",
"db_id": "P61235"
},
{
"db_name": "UniProt",
"db_id": "P61414"
},
{
"db_name": "UniProt",
"db_id": "P65863"
},
{
"db_name": "UniProt",
"db_id": "P65864"
},
{
"db_name": "UniProt",
"db_id": "P65865"
},
{
"db_name": "UniProt",
"db_id": "P65866"
},
{
"db_name": "UniProt",
"db_id": "P65867"
},
{
"db_name": "UniProt",
"db_id": "P65868"
},
{
"db_name": "UniProt",
"db_id": "P65869"
},
{
"db_name": "UniProt",
"db_id": "P78034"
},
{
"db_name": "UniProt",
"db_id": "Q27IM2"
},
{
"db_name": "UniProt",
"db_id": "Q57NM8"
},
{
"db_name": "UniProt",
"db_id": "Q59989"
},
{
"db_name": "UniProt",
"db_id": "Q5F9L4"
},
{
"db_name": "UniProt",
"db_id": "Q5FFA3"
},
{
"db_name": "UniProt",
"db_id": "Q5FMA9"
},
{
"db_name": "UniProt",
"db_id": "Q5FRT7"
},
{
"db_name": "UniProt",
"db_id": "Q5GTI9"
},
{
"db_name": "UniProt",
"db_id": "Q5GWR6"
},
{
"db_name": "UniProt",
"db_id": "Q5HC85"
},
{
"db_name": "UniProt",
"db_id": "Q5HIH3"
},
{
"db_name": "UniProt",
"db_id": "Q5HRQ3"
},
{
"db_name": "UniProt",
"db_id": "Q5HWF9"
},
{
"db_name": "UniProt",
"db_id": "Q5JDB8"
},
{
"db_name": "UniProt",
"db_id": "Q5L3U7"
},
{
"db_name": "UniProt",
"db_id": "Q5LV91"
},
{
"db_name": "UniProt",
"db_id": "Q5M222"
},
{
"db_name": "UniProt",
"db_id": "Q5M6L4"
},
{
"db_name": "UniProt",
"db_id": "Q5N2J4"
},
{
"db_name": "UniProt",
"db_id": "Q5NGZ6"
},
{
"db_name": "UniProt",
"db_id": "Q5NL75"
},
{
"db_name": "UniProt",
"db_id": "Q5P722"
},
{
"db_name": "UniProt",
"db_id": "Q5P9A6"
},
{
"db_name": "UniProt",
"db_id": "Q5PCR7"
},
{
"db_name": "UniProt",
"db_id": "Q5QV03"
},
{
"db_name": "UniProt",
"db_id": "Q5SHZ2"
},
{
"db_name": "UniProt",
"db_id": "Q5V1D3"
},
{
"db_name": "UniProt",
"db_id": "Q5WAD6"
},
{
"db_name": "UniProt",
"db_id": "Q5WTE7"
},
{
"db_name": "UniProt",
"db_id": "Q5X1N7"
},
{
"db_name": "UniProt",
"db_id": "Q5XEM3"
},
{
"db_name": "UniProt",
"db_id": "Q5YPZ6"
},
{
"db_name": "UniProt",
"db_id": "Q5ZS66"
},
{
"db_name": "UniProt",
"db_id": "Q601M5"
},
{
"db_name": "UniProt",
"db_id": "Q60363"
},
{
"db_name": "UniProt",
"db_id": "Q60A14"
},
{
"db_name": "UniProt",
"db_id": "Q62FC1"
},
{
"db_name": "UniProt",
"db_id": "Q63HI2"
},
{
"db_name": "UniProt",
"db_id": "Q63XM0"
},
{
"db_name": "UniProt",
"db_id": "Q64X30"
},
{
"db_name": "UniProt",
"db_id": "Q65PG8"
},
{
"db_name": "UniProt",
"db_id": "Q65V47"
},
{
"db_name": "UniProt",
"db_id": "Q65ZY7"
},
{
"db_name": "UniProt",
"db_id": "Q66AY1"
},
{
"db_name": "UniProt",
"db_id": "Q67JD0"
},
{
"db_name": "UniProt",
"db_id": "Q68WD4"
},
{
"db_name": "UniProt",
"db_id": "Q6AAC7"
},
{
"db_name": "UniProt",
"db_id": "Q6ADQ8"
},
{
"db_name": "UniProt",
"db_id": "Q6AJL9"
},
{
"db_name": "UniProt",
"db_id": "Q6D557"
},
{
"db_name": "UniProt",
"db_id": "Q6F240"
},
{
"db_name": "UniProt",
"db_id": "Q6F8I7"
},
{
"db_name": "UniProt",
"db_id": "Q6G0F9"
},
{
"db_name": "UniProt",
"db_id": "Q6G2L1"
},
{
"db_name": "UniProt",
"db_id": "Q6GBY6"
},
{
"db_name": "UniProt",
"db_id": "Q6GJG9"
},
{
"db_name": "UniProt",
"db_id": "Q6HPW6"
},
{
"db_name": "UniProt",
"db_id": "Q6KHA3"
},
{
"db_name": "UniProt",
"db_id": "Q6LNA9"
},
{
"db_name": "UniProt",
"db_id": "Q6MJR3"
},
{
"db_name": "UniProt",
"db_id": "Q6MS28"
},
{
"db_name": "UniProt",
"db_id": "Q6N1P9"
},
{
"db_name": "UniProt",
"db_id": "Q6NI78"
},
{
"db_name": "UniProt",
"db_id": "Q6YP15"
},
{
"db_name": "UniProt",
"db_id": "Q6YR64"
},
{
"db_name": "UniProt",
"db_id": "Q724K0"
},
{
"db_name": "UniProt",
"db_id": "Q72BR1"
},
{
"db_name": "UniProt",
"db_id": "Q72IA8"
},
{
"db_name": "UniProt",
"db_id": "Q72RZ0"
},
{
"db_name": "UniProt",
"db_id": "Q73FF7"
},
{
"db_name": "UniProt",
"db_id": "Q73II8"
},
{
"db_name": "UniProt",
"db_id": "Q73Q01"
},
{
"db_name": "UniProt",
"db_id": "Q741V9"
},
{
"db_name": "UniProt",
"db_id": "Q74FE6"
},
{
"db_name": "UniProt",
"db_id": "Q74LA8"
},
{
"db_name": "UniProt",
"db_id": "Q7M7U8"
},
{
"db_name": "UniProt",
"db_id": "Q7MMZ2"
},
{
"db_name": "UniProt",
"db_id": "Q7MXK9"
},
{
"db_name": "UniProt",
"db_id": "Q7N5A1"
},
{
"db_name": "UniProt",
"db_id": "Q7NN75"
},
{
"db_name": "UniProt",
"db_id": "Q7NQT1"
},
{
"db_name": "UniProt",
"db_id": "Q7U9I5"
},
{
"db_name": "UniProt",
"db_id": "Q7UKV0"
},
{
"db_name": "UniProt",
"db_id": "Q7V342"
},
{
"db_name": "UniProt",
"db_id": "Q7V4V4"
},
{
"db_name": "UniProt",
"db_id": "Q7VDT7"
},
{
"db_name": "UniProt",
"db_id": "Q7VG29"
},
{
"db_name": "UniProt",
"db_id": "Q7VMI1"
},
{
"db_name": "UniProt",
"db_id": "Q7VUH3"
},
{
"db_name": "UniProt",
"db_id": "Q7W179"
},
{
"db_name": "UniProt",
"db_id": "Q7WNY2"
},
{
"db_name": "UniProt",
"db_id": "Q81J96"
},
{
"db_name": "UniProt",
"db_id": "Q81VY9"
},
{
"db_name": "UniProt",
"db_id": "Q821W6"
},
{
"db_name": "UniProt",
"db_id": "Q82HE5"
},
{
"db_name": "UniProt",
"db_id": "Q82TQ6"
},
{
"db_name": "UniProt",
"db_id": "Q839C0"
},
{
"db_name": "UniProt",
"db_id": "Q83AP0"
},
{
"db_name": "UniProt",
"db_id": "Q83FR1"
},
{
"db_name": "UniProt",
"db_id": "Q83HD8"
},
{
"db_name": "UniProt",
"db_id": "Q83LE1"
},
{
"db_name": "UniProt",
"db_id": "Q86Y79"
},
{
"db_name": "UniProt",
"db_id": "Q877G5"
},
{
"db_name": "UniProt",
"db_id": "Q87A24"
},
{
"db_name": "UniProt",
"db_id": "Q87RN9"
},
{
"db_name": "UniProt",
"db_id": "Q888C8"
},
{
"db_name": "UniProt",
"db_id": "Q88PX8"
},
{
"db_name": "UniProt",
"db_id": "Q88Z39"
},
{
"db_name": "UniProt",
"db_id": "Q899I4"
},
{
"db_name": "UniProt",
"db_id": "Q89DJ9"
},
{
"db_name": "UniProt",
"db_id": "Q89YZ2"
},
{
"db_name": "UniProt",
"db_id": "Q8BW00"
},
{
"db_name": "UniProt",
"db_id": "Q8CQU9"
},
{
"db_name": "UniProt",
"db_id": "Q8CXP8"
},
{
"db_name": "UniProt",
"db_id": "Q8D2K4"
},
{
"db_name": "UniProt",
"db_id": "Q8DFF4"
},
{
"db_name": "UniProt",
"db_id": "Q8DJ45"
},
{
"db_name": "UniProt",
"db_id": "Q8DRQ2"
},
{
"db_name": "UniProt",
"db_id": "Q8DWN5"
},
{
"db_name": "UniProt",
"db_id": "Q8E2I1"
},
{
"db_name": "UniProt",
"db_id": "Q8E7Y8"
},
{
"db_name": "UniProt",
"db_id": "Q8EHN5"
},
{
"db_name": "UniProt",
"db_id": "Q8EWQ8"
},
{
"db_name": "UniProt",
"db_id": "Q8F3Q2"
},
{
"db_name": "UniProt",
"db_id": "Q8FQV6"
},
{
"db_name": "UniProt",
"db_id": "Q8G5I6"
},
{
"db_name": "UniProt",
"db_id": "Q8K8Z7"
},
{
"db_name": "UniProt",
"db_id": "Q8K9V3"
},
{
"db_name": "UniProt",
"db_id": "Q8KD05"
},
{
"db_name": "UniProt",
"db_id": "Q8P327"
},
{
"db_name": "UniProt",
"db_id": "Q8PC61"
},
{
"db_name": "UniProt",
"db_id": "Q8PNT8"
},
{
"db_name": "UniProt",
"db_id": "Q8Q0M4"
},
{
"db_name": "UniProt",
"db_id": "Q8R757"
},
{
"db_name": "UniProt",
"db_id": "Q8RIJ5"
},
{
"db_name": "UniProt",
"db_id": "Q8RLD7"
},
{
"db_name": "UniProt",
"db_id": "Q8TKX4"
},
{
"db_name": "UniProt",
"db_id": "Q8TV04"
},
{
"db_name": "UniProt",
"db_id": "Q8U0N0"
},
{
"db_name": "UniProt",
"db_id": "Q8UD97"
},
{
"db_name": "UniProt",
"db_id": "Q8XHJ8"
},
{
"db_name": "UniProt",
"db_id": "Q8Y2E3"
},
{
"db_name": "UniProt",
"db_id": "Q8YAD1"
},
{
"db_name": "UniProt",
"db_id": "Q8YYK4"
},
{
"db_name": "UniProt",
"db_id": "Q8ZEY4"
},
{
"db_name": "UniProt",
"db_id": "Q8ZYM4"
},
{
"db_name": "UniProt",
"db_id": "Q92F62"
},
{
"db_name": "UniProt",
"db_id": "Q92H41"
},
{
"db_name": "UniProt",
"db_id": "Q92N67"
},
{
"db_name": "UniProt",
"db_id": "Q976I0"
},
{
"db_name": "UniProt",
"db_id": "Q97CB4"
},
{
"db_name": "UniProt",
"db_id": "Q97E97"
},
{
"db_name": "UniProt",
"db_id": "Q97TD1"
},
{
"db_name": "UniProt",
"db_id": "Q980V1"
},
{
"db_name": "UniProt",
"db_id": "Q98HV6"
},
{
"db_name": "UniProt",
"db_id": "Q98PE2"
},
{
"db_name": "UniProt",
"db_id": "Q9A206"
},
{
"db_name": "UniProt",
"db_id": "Q9AAV9"
},
{
"db_name": "UniProt",
"db_id": "Q9AEQ5"
},
{
"db_name": "UniProt",
"db_id": "Q9CD49"
},
{
"db_name": "UniProt",
"db_id": "Q9CJI1"
},
{
"db_name": "UniProt",
"db_id": "Q9F8Q3"
},
{
"db_name": "UniProt",
"db_id": "Q9GL67"
},
{
"db_name": "UniProt",
"db_id": "Q9HLW6"
},
{
"db_name": "UniProt",
"db_id": "Q9HVC3"
},
{
"db_name": "UniProt",
"db_id": "Q9J5H2"
},
{
"db_name": "UniProt",
"db_id": "Q9JV42"
},
{
"db_name": "UniProt",
"db_id": "Q9K029"
},
{
"db_name": "UniProt",
"db_id": "Q9K3T8"
},
{
"db_name": "UniProt",
"db_id": "Q9KGJ3"
},
{
"db_name": "UniProt",
"db_id": "Q9KQ21"
},
{
"db_name": "UniProt",
"db_id": "Q9PA78"
},
{
"db_name": "UniProt",
"db_id": "Q9PII7"
},
{
"db_name": "UniProt",
"db_id": "Q9PR67"
},
{
"db_name": "UniProt",
"db_id": "Q9RRW3"
},
{
"db_name": "UniProt",
"db_id": "Q9V108"
},
{
"db_name": "UniProt",
"db_id": "Q9X1W1"
},
{
"db_name": "UniProt",
"db_id": "Q9XT35"
},
{
"db_name": "UniProt",
"db_id": "Q9YBD6"
},
{
"db_name": "UniProt",
"db_id": "Q9Z6V6"
},
{
"db_name": "UniProt",
"db_id": "Q9ZCV4"
},
{
"db_name": "UniProt",
"db_id": "Q9ZJC3"
}
]
},
{
"id": "DS.d52.s1.e0",
"type": "compound",
"text": [
"vitamin D"
],
"offsets": [
[
300,
309
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5280795"
}
]
},
{
"id": "DS.d52.s1.e1",
"type": "protein",
"text": [
"PTH"
],
"offsets": [
[
397,
400
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O27732"
},
{
"db_name": "UniProt",
"db_id": "O28185"
},
{
"db_name": "UniProt",
"db_id": "O66677"
},
{
"db_name": "UniProt",
"db_id": "O74017"
},
{
"db_name": "UniProt",
"db_id": "O74806"
},
{
"db_name": "UniProt",
"db_id": "O83975"
},
{
"db_name": "UniProt",
"db_id": "O84806"
},
{
"db_name": "UniProt",
"db_id": "O85235"
},
{
"db_name": "UniProt",
"db_id": "P01268"
},
{
"db_name": "UniProt",
"db_id": "P01269"
},
{
"db_name": "UniProt",
"db_id": "P01270"
},
{
"db_name": "UniProt",
"db_id": "P04089"
},
{
"db_name": "UniProt",
"db_id": "P0A281"
},
{
"db_name": "UniProt",
"db_id": "P0A282"
},
{
"db_name": "UniProt",
"db_id": "P0A7D1"
},
{
"db_name": "UniProt",
"db_id": "P0A7D2"
},
{
"db_name": "UniProt",
"db_id": "P0A7D3"
},
{
"db_name": "UniProt",
"db_id": "P15743"
},
{
"db_name": "UniProt",
"db_id": "P37470"
},
{
"db_name": "UniProt",
"db_id": "P38876"
},
{
"db_name": "UniProt",
"db_id": "P44682"
},
{
"db_name": "UniProt",
"db_id": "P47329"
},
{
"db_name": "UniProt",
"db_id": "P47714"
},
{
"db_name": "UniProt",
"db_id": "P49607"
},
{
"db_name": "UniProt",
"db_id": "P52212"
},
{
"db_name": "UniProt",
"db_id": "P56077"
},
{
"db_name": "UniProt",
"db_id": "P57287"
},
{
"db_name": "UniProt",
"db_id": "P57820"
},
{
"db_name": "UniProt",
"db_id": "P59490"
},
{
"db_name": "UniProt",
"db_id": "P61234"
},
{
"db_name": "UniProt",
"db_id": "P61235"
},
{
"db_name": "UniProt",
"db_id": "P61414"
},
{
"db_name": "UniProt",
"db_id": "P65863"
},
{
"db_name": "UniProt",
"db_id": "P65864"
},
{
"db_name": "UniProt",
"db_id": "P65865"
},
{
"db_name": "UniProt",
"db_id": "P65866"
},
{
"db_name": "UniProt",
"db_id": "P65867"
},
{
"db_name": "UniProt",
"db_id": "P65868"
},
{
"db_name": "UniProt",
"db_id": "P65869"
},
{
"db_name": "UniProt",
"db_id": "P78034"
},
{
"db_name": "UniProt",
"db_id": "Q27IM2"
},
{
"db_name": "UniProt",
"db_id": "Q57NM8"
},
{
"db_name": "UniProt",
"db_id": "Q59989"
},
{
"db_name": "UniProt",
"db_id": "Q5F9L4"
},
{
"db_name": "UniProt",
"db_id": "Q5FFA3"
},
{
"db_name": "UniProt",
"db_id": "Q5FMA9"
},
{
"db_name": "UniProt",
"db_id": "Q5FRT7"
},
{
"db_name": "UniProt",
"db_id": "Q5GTI9"
},
{
"db_name": "UniProt",
"db_id": "Q5GWR6"
},
{
"db_name": "UniProt",
"db_id": "Q5HC85"
},
{
"db_name": "UniProt",
"db_id": "Q5HIH3"
},
{
"db_name": "UniProt",
"db_id": "Q5HRQ3"
},
{
"db_name": "UniProt",
"db_id": "Q5HWF9"
},
{
"db_name": "UniProt",
"db_id": "Q5JDB8"
},
{
"db_name": "UniProt",
"db_id": "Q5L3U7"
},
{
"db_name": "UniProt",
"db_id": "Q5LV91"
},
{
"db_name": "UniProt",
"db_id": "Q5M222"
},
{
"db_name": "UniProt",
"db_id": "Q5M6L4"
},
{
"db_name": "UniProt",
"db_id": "Q5N2J4"
},
{
"db_name": "UniProt",
"db_id": "Q5NGZ6"
},
{
"db_name": "UniProt",
"db_id": "Q5NL75"
},
{
"db_name": "UniProt",
"db_id": "Q5P722"
},
{
"db_name": "UniProt",
"db_id": "Q5P9A6"
},
{
"db_name": "UniProt",
"db_id": "Q5PCR7"
},
{
"db_name": "UniProt",
"db_id": "Q5QV03"
},
{
"db_name": "UniProt",
"db_id": "Q5SHZ2"
},
{
"db_name": "UniProt",
"db_id": "Q5V1D3"
},
{
"db_name": "UniProt",
"db_id": "Q5WAD6"
},
{
"db_name": "UniProt",
"db_id": "Q5WTE7"
},
{
"db_name": "UniProt",
"db_id": "Q5X1N7"
},
{
"db_name": "UniProt",
"db_id": "Q5XEM3"
},
{
"db_name": "UniProt",
"db_id": "Q5YPZ6"
},
{
"db_name": "UniProt",
"db_id": "Q5ZS66"
},
{
"db_name": "UniProt",
"db_id": "Q601M5"
},
{
"db_name": "UniProt",
"db_id": "Q60363"
},
{
"db_name": "UniProt",
"db_id": "Q60A14"
},
{
"db_name": "UniProt",
"db_id": "Q62FC1"
},
{
"db_name": "UniProt",
"db_id": "Q63HI2"
},
{
"db_name": "UniProt",
"db_id": "Q63XM0"
},
{
"db_name": "UniProt",
"db_id": "Q64X30"
},
{
"db_name": "UniProt",
"db_id": "Q65PG8"
},
{
"db_name": "UniProt",
"db_id": "Q65V47"
},
{
"db_name": "UniProt",
"db_id": "Q65ZY7"
},
{
"db_name": "UniProt",
"db_id": "Q66AY1"
},
{
"db_name": "UniProt",
"db_id": "Q67JD0"
},
{
"db_name": "UniProt",
"db_id": "Q68WD4"
},
{
"db_name": "UniProt",
"db_id": "Q6AAC7"
},
{
"db_name": "UniProt",
"db_id": "Q6ADQ8"
},
{
"db_name": "UniProt",
"db_id": "Q6AJL9"
},
{
"db_name": "UniProt",
"db_id": "Q6D557"
},
{
"db_name": "UniProt",
"db_id": "Q6F240"
},
{
"db_name": "UniProt",
"db_id": "Q6F8I7"
},
{
"db_name": "UniProt",
"db_id": "Q6G0F9"
},
{
"db_name": "UniProt",
"db_id": "Q6G2L1"
},
{
"db_name": "UniProt",
"db_id": "Q6GBY6"
},
{
"db_name": "UniProt",
"db_id": "Q6GJG9"
},
{
"db_name": "UniProt",
"db_id": "Q6HPW6"
},
{
"db_name": "UniProt",
"db_id": "Q6KHA3"
},
{
"db_name": "UniProt",
"db_id": "Q6LNA9"
},
{
"db_name": "UniProt",
"db_id": "Q6MJR3"
},
{
"db_name": "UniProt",
"db_id": "Q6MS28"
},
{
"db_name": "UniProt",
"db_id": "Q6N1P9"
},
{
"db_name": "UniProt",
"db_id": "Q6NI78"
},
{
"db_name": "UniProt",
"db_id": "Q6YP15"
},
{
"db_name": "UniProt",
"db_id": "Q6YR64"
},
{
"db_name": "UniProt",
"db_id": "Q724K0"
},
{
"db_name": "UniProt",
"db_id": "Q72BR1"
},
{
"db_name": "UniProt",
"db_id": "Q72IA8"
},
{
"db_name": "UniProt",
"db_id": "Q72RZ0"
},
{
"db_name": "UniProt",
"db_id": "Q73FF7"
},
{
"db_name": "UniProt",
"db_id": "Q73II8"
},
{
"db_name": "UniProt",
"db_id": "Q73Q01"
},
{
"db_name": "UniProt",
"db_id": "Q741V9"
},
{
"db_name": "UniProt",
"db_id": "Q74FE6"
},
{
"db_name": "UniProt",
"db_id": "Q74LA8"
},
{
"db_name": "UniProt",
"db_id": "Q7M7U8"
},
{
"db_name": "UniProt",
"db_id": "Q7MMZ2"
},
{
"db_name": "UniProt",
"db_id": "Q7MXK9"
},
{
"db_name": "UniProt",
"db_id": "Q7N5A1"
},
{
"db_name": "UniProt",
"db_id": "Q7NN75"
},
{
"db_name": "UniProt",
"db_id": "Q7NQT1"
},
{
"db_name": "UniProt",
"db_id": "Q7U9I5"
},
{
"db_name": "UniProt",
"db_id": "Q7UKV0"
},
{
"db_name": "UniProt",
"db_id": "Q7V342"
},
{
"db_name": "UniProt",
"db_id": "Q7V4V4"
},
{
"db_name": "UniProt",
"db_id": "Q7VDT7"
},
{
"db_name": "UniProt",
"db_id": "Q7VG29"
},
{
"db_name": "UniProt",
"db_id": "Q7VMI1"
},
{
"db_name": "UniProt",
"db_id": "Q7VUH3"
},
{
"db_name": "UniProt",
"db_id": "Q7W179"
},
{
"db_name": "UniProt",
"db_id": "Q7WNY2"
},
{
"db_name": "UniProt",
"db_id": "Q81J96"
},
{
"db_name": "UniProt",
"db_id": "Q81VY9"
},
{
"db_name": "UniProt",
"db_id": "Q821W6"
},
{
"db_name": "UniProt",
"db_id": "Q82HE5"
},
{
"db_name": "UniProt",
"db_id": "Q82TQ6"
},
{
"db_name": "UniProt",
"db_id": "Q839C0"
},
{
"db_name": "UniProt",
"db_id": "Q83AP0"
},
{
"db_name": "UniProt",
"db_id": "Q83FR1"
},
{
"db_name": "UniProt",
"db_id": "Q83HD8"
},
{
"db_name": "UniProt",
"db_id": "Q83LE1"
},
{
"db_name": "UniProt",
"db_id": "Q86Y79"
},
{
"db_name": "UniProt",
"db_id": "Q877G5"
},
{
"db_name": "UniProt",
"db_id": "Q87A24"
},
{
"db_name": "UniProt",
"db_id": "Q87RN9"
},
{
"db_name": "UniProt",
"db_id": "Q888C8"
},
{
"db_name": "UniProt",
"db_id": "Q88PX8"
},
{
"db_name": "UniProt",
"db_id": "Q88Z39"
},
{
"db_name": "UniProt",
"db_id": "Q899I4"
},
{
"db_name": "UniProt",
"db_id": "Q89DJ9"
},
{
"db_name": "UniProt",
"db_id": "Q89YZ2"
},
{
"db_name": "UniProt",
"db_id": "Q8BW00"
},
{
"db_name": "UniProt",
"db_id": "Q8CQU9"
},
{
"db_name": "UniProt",
"db_id": "Q8CXP8"
},
{
"db_name": "UniProt",
"db_id": "Q8D2K4"
},
{
"db_name": "UniProt",
"db_id": "Q8DFF4"
},
{
"db_name": "UniProt",
"db_id": "Q8DJ45"
},
{
"db_name": "UniProt",
"db_id": "Q8DRQ2"
},
{
"db_name": "UniProt",
"db_id": "Q8DWN5"
},
{
"db_name": "UniProt",
"db_id": "Q8E2I1"
},
{
"db_name": "UniProt",
"db_id": "Q8E7Y8"
},
{
"db_name": "UniProt",
"db_id": "Q8EHN5"
},
{
"db_name": "UniProt",
"db_id": "Q8EWQ8"
},
{
"db_name": "UniProt",
"db_id": "Q8F3Q2"
},
{
"db_name": "UniProt",
"db_id": "Q8FQV6"
},
{
"db_name": "UniProt",
"db_id": "Q8G5I6"
},
{
"db_name": "UniProt",
"db_id": "Q8K8Z7"
},
{
"db_name": "UniProt",
"db_id": "Q8K9V3"
},
{
"db_name": "UniProt",
"db_id": "Q8KD05"
},
{
"db_name": "UniProt",
"db_id": "Q8P327"
},
{
"db_name": "UniProt",
"db_id": "Q8PC61"
},
{
"db_name": "UniProt",
"db_id": "Q8PNT8"
},
{
"db_name": "UniProt",
"db_id": "Q8Q0M4"
},
{
"db_name": "UniProt",
"db_id": "Q8R757"
},
{
"db_name": "UniProt",
"db_id": "Q8RIJ5"
},
{
"db_name": "UniProt",
"db_id": "Q8RLD7"
},
{
"db_name": "UniProt",
"db_id": "Q8TKX4"
},
{
"db_name": "UniProt",
"db_id": "Q8TV04"
},
{
"db_name": "UniProt",
"db_id": "Q8U0N0"
},
{
"db_name": "UniProt",
"db_id": "Q8UD97"
},
{
"db_name": "UniProt",
"db_id": "Q8XHJ8"
},
{
"db_name": "UniProt",
"db_id": "Q8Y2E3"
},
{
"db_name": "UniProt",
"db_id": "Q8YAD1"
},
{
"db_name": "UniProt",
"db_id": "Q8YYK4"
},
{
"db_name": "UniProt",
"db_id": "Q8ZEY4"
},
{
"db_name": "UniProt",
"db_id": "Q8ZYM4"
},
{
"db_name": "UniProt",
"db_id": "Q92F62"
},
{
"db_name": "UniProt",
"db_id": "Q92H41"
},
{
"db_name": "UniProt",
"db_id": "Q92N67"
},
{
"db_name": "UniProt",
"db_id": "Q976I0"
},
{
"db_name": "UniProt",
"db_id": "Q97CB4"
},
{
"db_name": "UniProt",
"db_id": "Q97E97"
},
{
"db_name": "UniProt",
"db_id": "Q97TD1"
},
{
"db_name": "UniProt",
"db_id": "Q980V1"
},
{
"db_name": "UniProt",
"db_id": "Q98HV6"
},
{
"db_name": "UniProt",
"db_id": "Q98PE2"
},
{
"db_name": "UniProt",
"db_id": "Q9A206"
},
{
"db_name": "UniProt",
"db_id": "Q9AAV9"
},
{
"db_name": "UniProt",
"db_id": "Q9AEQ5"
},
{
"db_name": "UniProt",
"db_id": "Q9CD49"
},
{
"db_name": "UniProt",
"db_id": "Q9CJI1"
},
{
"db_name": "UniProt",
"db_id": "Q9F8Q3"
},
{
"db_name": "UniProt",
"db_id": "Q9GL67"
},
{
"db_name": "UniProt",
"db_id": "Q9HLW6"
},
{
"db_name": "UniProt",
"db_id": "Q9HVC3"
},
{
"db_name": "UniProt",
"db_id": "Q9J5H2"
},
{
"db_name": "UniProt",
"db_id": "Q9JV42"
},
{
"db_name": "UniProt",
"db_id": "Q9K029"
},
{
"db_name": "UniProt",
"db_id": "Q9K3T8"
},
{
"db_name": "UniProt",
"db_id": "Q9KGJ3"
},
{
"db_name": "UniProt",
"db_id": "Q9KQ21"
},
{
"db_name": "UniProt",
"db_id": "Q9PA78"
},
{
"db_name": "UniProt",
"db_id": "Q9PII7"
},
{
"db_name": "UniProt",
"db_id": "Q9PR67"
},
{
"db_name": "UniProt",
"db_id": "Q9RRW3"
},
{
"db_name": "UniProt",
"db_id": "Q9V108"
},
{
"db_name": "UniProt",
"db_id": "Q9X1W1"
},
{
"db_name": "UniProt",
"db_id": "Q9XT35"
},
{
"db_name": "UniProt",
"db_id": "Q9YBD6"
},
{
"db_name": "UniProt",
"db_id": "Q9Z6V6"
},
{
"db_name": "UniProt",
"db_id": "Q9ZCV4"
},
{
"db_name": "UniProt",
"db_id": "Q9ZJC3"
}
]
},
{
"id": "DS.d52.s2.e0",
"type": "protein",
"text": [
"PTH"
],
"offsets": [
[
439,
442
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O27732"
},
{
"db_name": "UniProt",
"db_id": "O28185"
},
{
"db_name": "UniProt",
"db_id": "O66677"
},
{
"db_name": "UniProt",
"db_id": "O74017"
},
{
"db_name": "UniProt",
"db_id": "O74806"
},
{
"db_name": "UniProt",
"db_id": "O83975"
},
{
"db_name": "UniProt",
"db_id": "O84806"
},
{
"db_name": "UniProt",
"db_id": "O85235"
},
{
"db_name": "UniProt",
"db_id": "P01268"
},
{
"db_name": "UniProt",
"db_id": "P01269"
},
{
"db_name": "UniProt",
"db_id": "P01270"
},
{
"db_name": "UniProt",
"db_id": "P04089"
},
{
"db_name": "UniProt",
"db_id": "P0A281"
},
{
"db_name": "UniProt",
"db_id": "P0A282"
},
{
"db_name": "UniProt",
"db_id": "P0A7D1"
},
{
"db_name": "UniProt",
"db_id": "P0A7D2"
},
{
"db_name": "UniProt",
"db_id": "P0A7D3"
},
{
"db_name": "UniProt",
"db_id": "P15743"
},
{
"db_name": "UniProt",
"db_id": "P37470"
},
{
"db_name": "UniProt",
"db_id": "P38876"
},
{
"db_name": "UniProt",
"db_id": "P44682"
},
{
"db_name": "UniProt",
"db_id": "P47329"
},
{
"db_name": "UniProt",
"db_id": "P47714"
},
{
"db_name": "UniProt",
"db_id": "P49607"
},
{
"db_name": "UniProt",
"db_id": "P52212"
},
{
"db_name": "UniProt",
"db_id": "P56077"
},
{
"db_name": "UniProt",
"db_id": "P57287"
},
{
"db_name": "UniProt",
"db_id": "P57820"
},
{
"db_name": "UniProt",
"db_id": "P59490"
},
{
"db_name": "UniProt",
"db_id": "P61234"
},
{
"db_name": "UniProt",
"db_id": "P61235"
},
{
"db_name": "UniProt",
"db_id": "P61414"
},
{
"db_name": "UniProt",
"db_id": "P65863"
},
{
"db_name": "UniProt",
"db_id": "P65864"
},
{
"db_name": "UniProt",
"db_id": "P65865"
},
{
"db_name": "UniProt",
"db_id": "P65866"
},
{
"db_name": "UniProt",
"db_id": "P65867"
},
{
"db_name": "UniProt",
"db_id": "P65868"
},
{
"db_name": "UniProt",
"db_id": "P65869"
},
{
"db_name": "UniProt",
"db_id": "P78034"
},
{
"db_name": "UniProt",
"db_id": "Q27IM2"
},
{
"db_name": "UniProt",
"db_id": "Q57NM8"
},
{
"db_name": "UniProt",
"db_id": "Q59989"
},
{
"db_name": "UniProt",
"db_id": "Q5F9L4"
},
{
"db_name": "UniProt",
"db_id": "Q5FFA3"
},
{
"db_name": "UniProt",
"db_id": "Q5FMA9"
},
{
"db_name": "UniProt",
"db_id": "Q5FRT7"
},
{
"db_name": "UniProt",
"db_id": "Q5GTI9"
},
{
"db_name": "UniProt",
"db_id": "Q5GWR6"
},
{
"db_name": "UniProt",
"db_id": "Q5HC85"
},
{
"db_name": "UniProt",
"db_id": "Q5HIH3"
},
{
"db_name": "UniProt",
"db_id": "Q5HRQ3"
},
{
"db_name": "UniProt",
"db_id": "Q5HWF9"
},
{
"db_name": "UniProt",
"db_id": "Q5JDB8"
},
{
"db_name": "UniProt",
"db_id": "Q5L3U7"
},
{
"db_name": "UniProt",
"db_id": "Q5LV91"
},
{
"db_name": "UniProt",
"db_id": "Q5M222"
},
{
"db_name": "UniProt",
"db_id": "Q5M6L4"
},
{
"db_name": "UniProt",
"db_id": "Q5N2J4"
},
{
"db_name": "UniProt",
"db_id": "Q5NGZ6"
},
{
"db_name": "UniProt",
"db_id": "Q5NL75"
},
{
"db_name": "UniProt",
"db_id": "Q5P722"
},
{
"db_name": "UniProt",
"db_id": "Q5P9A6"
},
{
"db_name": "UniProt",
"db_id": "Q5PCR7"
},
{
"db_name": "UniProt",
"db_id": "Q5QV03"
},
{
"db_name": "UniProt",
"db_id": "Q5SHZ2"
},
{
"db_name": "UniProt",
"db_id": "Q5V1D3"
},
{
"db_name": "UniProt",
"db_id": "Q5WAD6"
},
{
"db_name": "UniProt",
"db_id": "Q5WTE7"
},
{
"db_name": "UniProt",
"db_id": "Q5X1N7"
},
{
"db_name": "UniProt",
"db_id": "Q5XEM3"
},
{
"db_name": "UniProt",
"db_id": "Q5YPZ6"
},
{
"db_name": "UniProt",
"db_id": "Q5ZS66"
},
{
"db_name": "UniProt",
"db_id": "Q601M5"
},
{
"db_name": "UniProt",
"db_id": "Q60363"
},
{
"db_name": "UniProt",
"db_id": "Q60A14"
},
{
"db_name": "UniProt",
"db_id": "Q62FC1"
},
{
"db_name": "UniProt",
"db_id": "Q63HI2"
},
{
"db_name": "UniProt",
"db_id": "Q63XM0"
},
{
"db_name": "UniProt",
"db_id": "Q64X30"
},
{
"db_name": "UniProt",
"db_id": "Q65PG8"
},
{
"db_name": "UniProt",
"db_id": "Q65V47"
},
{
"db_name": "UniProt",
"db_id": "Q65ZY7"
},
{
"db_name": "UniProt",
"db_id": "Q66AY1"
},
{
"db_name": "UniProt",
"db_id": "Q67JD0"
},
{
"db_name": "UniProt",
"db_id": "Q68WD4"
},
{
"db_name": "UniProt",
"db_id": "Q6AAC7"
},
{
"db_name": "UniProt",
"db_id": "Q6ADQ8"
},
{
"db_name": "UniProt",
"db_id": "Q6AJL9"
},
{
"db_name": "UniProt",
"db_id": "Q6D557"
},
{
"db_name": "UniProt",
"db_id": "Q6F240"
},
{
"db_name": "UniProt",
"db_id": "Q6F8I7"
},
{
"db_name": "UniProt",
"db_id": "Q6G0F9"
},
{
"db_name": "UniProt",
"db_id": "Q6G2L1"
},
{
"db_name": "UniProt",
"db_id": "Q6GBY6"
},
{
"db_name": "UniProt",
"db_id": "Q6GJG9"
},
{
"db_name": "UniProt",
"db_id": "Q6HPW6"
},
{
"db_name": "UniProt",
"db_id": "Q6KHA3"
},
{
"db_name": "UniProt",
"db_id": "Q6LNA9"
},
{
"db_name": "UniProt",
"db_id": "Q6MJR3"
},
{
"db_name": "UniProt",
"db_id": "Q6MS28"
},
{
"db_name": "UniProt",
"db_id": "Q6N1P9"
},
{
"db_name": "UniProt",
"db_id": "Q6NI78"
},
{
"db_name": "UniProt",
"db_id": "Q6YP15"
},
{
"db_name": "UniProt",
"db_id": "Q6YR64"
},
{
"db_name": "UniProt",
"db_id": "Q724K0"
},
{
"db_name": "UniProt",
"db_id": "Q72BR1"
},
{
"db_name": "UniProt",
"db_id": "Q72IA8"
},
{
"db_name": "UniProt",
"db_id": "Q72RZ0"
},
{
"db_name": "UniProt",
"db_id": "Q73FF7"
},
{
"db_name": "UniProt",
"db_id": "Q73II8"
},
{
"db_name": "UniProt",
"db_id": "Q73Q01"
},
{
"db_name": "UniProt",
"db_id": "Q741V9"
},
{
"db_name": "UniProt",
"db_id": "Q74FE6"
},
{
"db_name": "UniProt",
"db_id": "Q74LA8"
},
{
"db_name": "UniProt",
"db_id": "Q7M7U8"
},
{
"db_name": "UniProt",
"db_id": "Q7MMZ2"
},
{
"db_name": "UniProt",
"db_id": "Q7MXK9"
},
{
"db_name": "UniProt",
"db_id": "Q7N5A1"
},
{
"db_name": "UniProt",
"db_id": "Q7NN75"
},
{
"db_name": "UniProt",
"db_id": "Q7NQT1"
},
{
"db_name": "UniProt",
"db_id": "Q7U9I5"
},
{
"db_name": "UniProt",
"db_id": "Q7UKV0"
},
{
"db_name": "UniProt",
"db_id": "Q7V342"
},
{
"db_name": "UniProt",
"db_id": "Q7V4V4"
},
{
"db_name": "UniProt",
"db_id": "Q7VDT7"
},
{
"db_name": "UniProt",
"db_id": "Q7VG29"
},
{
"db_name": "UniProt",
"db_id": "Q7VMI1"
},
{
"db_name": "UniProt",
"db_id": "Q7VUH3"
},
{
"db_name": "UniProt",
"db_id": "Q7W179"
},
{
"db_name": "UniProt",
"db_id": "Q7WNY2"
},
{
"db_name": "UniProt",
"db_id": "Q81J96"
},
{
"db_name": "UniProt",
"db_id": "Q81VY9"
},
{
"db_name": "UniProt",
"db_id": "Q821W6"
},
{
"db_name": "UniProt",
"db_id": "Q82HE5"
},
{
"db_name": "UniProt",
"db_id": "Q82TQ6"
},
{
"db_name": "UniProt",
"db_id": "Q839C0"
},
{
"db_name": "UniProt",
"db_id": "Q83AP0"
},
{
"db_name": "UniProt",
"db_id": "Q83FR1"
},
{
"db_name": "UniProt",
"db_id": "Q83HD8"
},
{
"db_name": "UniProt",
"db_id": "Q83LE1"
},
{
"db_name": "UniProt",
"db_id": "Q86Y79"
},
{
"db_name": "UniProt",
"db_id": "Q877G5"
},
{
"db_name": "UniProt",
"db_id": "Q87A24"
},
{
"db_name": "UniProt",
"db_id": "Q87RN9"
},
{
"db_name": "UniProt",
"db_id": "Q888C8"
},
{
"db_name": "UniProt",
"db_id": "Q88PX8"
},
{
"db_name": "UniProt",
"db_id": "Q88Z39"
},
{
"db_name": "UniProt",
"db_id": "Q899I4"
},
{
"db_name": "UniProt",
"db_id": "Q89DJ9"
},
{
"db_name": "UniProt",
"db_id": "Q89YZ2"
},
{
"db_name": "UniProt",
"db_id": "Q8BW00"
},
{
"db_name": "UniProt",
"db_id": "Q8CQU9"
},
{
"db_name": "UniProt",
"db_id": "Q8CXP8"
},
{
"db_name": "UniProt",
"db_id": "Q8D2K4"
},
{
"db_name": "UniProt",
"db_id": "Q8DFF4"
},
{
"db_name": "UniProt",
"db_id": "Q8DJ45"
},
{
"db_name": "UniProt",
"db_id": "Q8DRQ2"
},
{
"db_name": "UniProt",
"db_id": "Q8DWN5"
},
{
"db_name": "UniProt",
"db_id": "Q8E2I1"
},
{
"db_name": "UniProt",
"db_id": "Q8E7Y8"
},
{
"db_name": "UniProt",
"db_id": "Q8EHN5"
},
{
"db_name": "UniProt",
"db_id": "Q8EWQ8"
},
{
"db_name": "UniProt",
"db_id": "Q8F3Q2"
},
{
"db_name": "UniProt",
"db_id": "Q8FQV6"
},
{
"db_name": "UniProt",
"db_id": "Q8G5I6"
},
{
"db_name": "UniProt",
"db_id": "Q8K8Z7"
},
{
"db_name": "UniProt",
"db_id": "Q8K9V3"
},
{
"db_name": "UniProt",
"db_id": "Q8KD05"
},
{
"db_name": "UniProt",
"db_id": "Q8P327"
},
{
"db_name": "UniProt",
"db_id": "Q8PC61"
},
{
"db_name": "UniProt",
"db_id": "Q8PNT8"
},
{
"db_name": "UniProt",
"db_id": "Q8Q0M4"
},
{
"db_name": "UniProt",
"db_id": "Q8R757"
},
{
"db_name": "UniProt",
"db_id": "Q8RIJ5"
},
{
"db_name": "UniProt",
"db_id": "Q8RLD7"
},
{
"db_name": "UniProt",
"db_id": "Q8TKX4"
},
{
"db_name": "UniProt",
"db_id": "Q8TV04"
},
{
"db_name": "UniProt",
"db_id": "Q8U0N0"
},
{
"db_name": "UniProt",
"db_id": "Q8UD97"
},
{
"db_name": "UniProt",
"db_id": "Q8XHJ8"
},
{
"db_name": "UniProt",
"db_id": "Q8Y2E3"
},
{
"db_name": "UniProt",
"db_id": "Q8YAD1"
},
{
"db_name": "UniProt",
"db_id": "Q8YYK4"
},
{
"db_name": "UniProt",
"db_id": "Q8ZEY4"
},
{
"db_name": "UniProt",
"db_id": "Q8ZYM4"
},
{
"db_name": "UniProt",
"db_id": "Q92F62"
},
{
"db_name": "UniProt",
"db_id": "Q92H41"
},
{
"db_name": "UniProt",
"db_id": "Q92N67"
},
{
"db_name": "UniProt",
"db_id": "Q976I0"
},
{
"db_name": "UniProt",
"db_id": "Q97CB4"
},
{
"db_name": "UniProt",
"db_id": "Q97E97"
},
{
"db_name": "UniProt",
"db_id": "Q97TD1"
},
{
"db_name": "UniProt",
"db_id": "Q980V1"
},
{
"db_name": "UniProt",
"db_id": "Q98HV6"
},
{
"db_name": "UniProt",
"db_id": "Q98PE2"
},
{
"db_name": "UniProt",
"db_id": "Q9A206"
},
{
"db_name": "UniProt",
"db_id": "Q9AAV9"
},
{
"db_name": "UniProt",
"db_id": "Q9AEQ5"
},
{
"db_name": "UniProt",
"db_id": "Q9CD49"
},
{
"db_name": "UniProt",
"db_id": "Q9CJI1"
},
{
"db_name": "UniProt",
"db_id": "Q9F8Q3"
},
{
"db_name": "UniProt",
"db_id": "Q9GL67"
},
{
"db_name": "UniProt",
"db_id": "Q9HLW6"
},
{
"db_name": "UniProt",
"db_id": "Q9HVC3"
},
{
"db_name": "UniProt",
"db_id": "Q9J5H2"
},
{
"db_name": "UniProt",
"db_id": "Q9JV42"
},
{
"db_name": "UniProt",
"db_id": "Q9K029"
},
{
"db_name": "UniProt",
"db_id": "Q9K3T8"
},
{
"db_name": "UniProt",
"db_id": "Q9KGJ3"
},
{
"db_name": "UniProt",
"db_id": "Q9KQ21"
},
{
"db_name": "UniProt",
"db_id": "Q9PA78"
},
{
"db_name": "UniProt",
"db_id": "Q9PII7"
},
{
"db_name": "UniProt",
"db_id": "Q9PR67"
},
{
"db_name": "UniProt",
"db_id": "Q9RRW3"
},
{
"db_name": "UniProt",
"db_id": "Q9V108"
},
{
"db_name": "UniProt",
"db_id": "Q9X1W1"
},
{
"db_name": "UniProt",
"db_id": "Q9XT35"
},
{
"db_name": "UniProt",
"db_id": "Q9YBD6"
},
{
"db_name": "UniProt",
"db_id": "Q9Z6V6"
},
{
"db_name": "UniProt",
"db_id": "Q9ZCV4"
},
{
"db_name": "UniProt",
"db_id": "Q9ZJC3"
}
]
},
{
"id": "DS.d52.s2.e1",
"type": "compound",
"text": [
"vitamin D"
],
"offsets": [
[
475,
484
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5280795"
}
]
}
] | [] | [] | [
{
"id": "DS.d52.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d52.s0.e0",
"arg2_id": "DS.d52.s0.e1",
"normalized": []
},
{
"id": "DS.d52.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d52.s1.e0",
"arg2_id": "DS.d52.s1.e1",
"normalized": []
},
{
"id": "DS.d52.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d52.s2.e1",
"arg2_id": "DS.d52.s2.e0",
"normalized": []
}
] |
DS.d53 | 18248398 | [
{
"id": "DS.d53.s0",
"text": [
"Leptin did not show any effect in long photoperiod but decreased proliferation by stimulating melatonin in short photoperiod."
],
"offsets": [
[
0,
125
]
],
"type": ""
}
] | [
{
"id": "DS.d53.s0.e0",
"type": "protein",
"text": [
"Leptin"
],
"offsets": [
[
0,
6
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O02750"
},
{
"db_name": "UniProt",
"db_id": "O93416"
},
{
"db_name": "UniProt",
"db_id": "Q28603"
},
{
"db_name": "UniProt",
"db_id": "Q95189"
},
{
"db_name": "UniProt",
"db_id": "Q95234"
}
]
},
{
"id": "DS.d53.s0.e1",
"type": "compound",
"text": [
"melatonin"
],
"offsets": [
[
94,
103
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "896"
}
]
}
] | [] | [] | [
{
"id": "DS.d53.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d53.s0.e1",
"arg2_id": "DS.d53.s0.e0",
"normalized": []
}
] |
DS.d54 | 18249383 | [
{
"id": "DS.d54.s0",
"text": [
"To compare the changes in body composition and in leptin levels in postmenopausal women receiving hormone therapy (HT) or tibolone."
],
"offsets": [
[
0,
131
]
],
"type": ""
}
] | [
{
"id": "DS.d54.s0.e0",
"type": "protein",
"text": [
"leptin"
],
"offsets": [
[
50,
56
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O02750"
},
{
"db_name": "UniProt",
"db_id": "O93416"
},
{
"db_name": "UniProt",
"db_id": "Q28603"
},
{
"db_name": "UniProt",
"db_id": "Q95189"
},
{
"db_name": "UniProt",
"db_id": "Q95234"
}
]
},
{
"id": "DS.d54.s0.e1",
"type": "compound",
"text": [
"tibolone"
],
"offsets": [
[
122,
130
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "444008"
}
]
}
] | [] | [] | [
{
"id": "DS.d54.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d54.s0.e1",
"arg2_id": "DS.d54.s0.e0",
"normalized": []
}
] |
DS.d55 | 18249399 | [
{
"id": "DS.d55.s0",
"text": [
"Common 677C-->T mutation of the 5,10-methylenetetrahydrofolate reductase gene affects follicular estradiol synthesis."
],
"offsets": [
[
0,
120
]
],
"type": ""
}
] | [
{
"id": "DS.d55.s0.e0",
"type": "protein",
"text": [
"5,10-methylenetetrahydrofolate reductase"
],
"offsets": [
[
35,
75
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O54235"
},
{
"db_name": "UniProt",
"db_id": "O67422"
},
{
"db_name": "UniProt",
"db_id": "P0AEZ1"
},
{
"db_name": "UniProt",
"db_id": "P0AEZ2"
},
{
"db_name": "UniProt",
"db_id": "P11003"
},
{
"db_name": "UniProt",
"db_id": "P45208"
},
{
"db_name": "UniProt",
"db_id": "P57154"
},
{
"db_name": "UniProt",
"db_id": "P71319"
},
{
"db_name": "UniProt",
"db_id": "Q89B13"
},
{
"db_name": "UniProt",
"db_id": "Q8KA62"
}
]
},
{
"id": "DS.d55.s0.e1",
"type": "compound",
"text": [
"estradiol"
],
"offsets": [
[
100,
109
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5757"
}
]
}
] | [] | [] | [
{
"id": "DS.d55.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d55.s0.e1",
"arg2_id": "DS.d55.s0.e0",
"normalized": []
}
] |
DS.d56 | 18253022 | [
{
"id": "DS.d56.s0",
"text": [
"Surprisingly, a deletion of the pilR gene affected not only insoluble Fe(III) reduction, which requires pili, but also soluble Fe(III) reduction, which, in contrast, does not require pili."
],
"offsets": [
[
0,
188
]
],
"type": ""
}
] | [
{
"id": "DS.d56.s0.e0",
"type": "protein",
"text": [
"pilR"
],
"offsets": [
[
32,
36
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q00934"
}
]
},
{
"id": "DS.d56.s0.e1",
"type": "compound",
"text": [
"Fe(III"
],
"offsets": [
[
70,
76
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "29936"
}
]
},
{
"id": "DS.d56.s0.e2",
"type": "compound",
"text": [
"Fe(III"
],
"offsets": [
[
127,
133
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "29936"
}
]
}
] | [] | [] | [
{
"id": "DS.d56.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d56.s0.e1",
"arg2_id": "DS.d56.s0.e0",
"normalized": []
}
] |
DS.d57 | 18253697 | [
{
"id": "DS.d57.s0",
"text": [
"Furthermore, the suppressive effects of P on cytochrome c release and caspase-9 and caspase-3 activation in serum-deprived MC3T3-E1 cells were also reversed by RU486."
],
"offsets": [
[
0,
166
]
],
"type": ""
}
] | [
{
"id": "DS.d57.s0.e0",
"type": "protein",
"text": [
"cytochrome c"
],
"offsets": [
[
45,
57
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O07091"
},
{
"db_name": "UniProt",
"db_id": "O13393"
},
{
"db_name": "UniProt",
"db_id": "O22642"
},
{
"db_name": "UniProt",
"db_id": "O93863"
},
{
"db_name": "UniProt",
"db_id": "P00002"
},
{
"db_name": "UniProt",
"db_id": "P00003"
},
{
"db_name": "UniProt",
"db_id": "P00004"
},
{
"db_name": "UniProt",
"db_id": "P00007"
},
{
"db_name": "UniProt",
"db_id": "P00008"
},
{
"db_name": "UniProt",
"db_id": "P00011"
},
{
"db_name": "UniProt",
"db_id": "P00012"
},
{
"db_name": "UniProt",
"db_id": "P00013"
},
{
"db_name": "UniProt",
"db_id": "P00014"
},
{
"db_name": "UniProt",
"db_id": "P00017"
},
{
"db_name": "UniProt",
"db_id": "P00018"
},
{
"db_name": "UniProt",
"db_id": "P00019"
},
{
"db_name": "UniProt",
"db_id": "P00020"
},
{
"db_name": "UniProt",
"db_id": "P00021"
},
{
"db_name": "UniProt",
"db_id": "P00022"
},
{
"db_name": "UniProt",
"db_id": "P00024"
},
{
"db_name": "UniProt",
"db_id": "P00025"
},
{
"db_name": "UniProt",
"db_id": "P00027"
},
{
"db_name": "UniProt",
"db_id": "P00028"
},
{
"db_name": "UniProt",
"db_id": "P00029"
},
{
"db_name": "UniProt",
"db_id": "P00030"
},
{
"db_name": "UniProt",
"db_id": "P00031"
},
{
"db_name": "UniProt",
"db_id": "P00032"
},
{
"db_name": "UniProt",
"db_id": "P00035"
},
{
"db_name": "UniProt",
"db_id": "P00036"
},
{
"db_name": "UniProt",
"db_id": "P00037"
},
{
"db_name": "UniProt",
"db_id": "P00038"
},
{
"db_name": "UniProt",
"db_id": "P00039"
},
{
"db_name": "UniProt",
"db_id": "P00040"
},
{
"db_name": "UniProt",
"db_id": "P00041"
},
{
"db_name": "UniProt",
"db_id": "P00042"
},
{
"db_name": "UniProt",
"db_id": "P00043"
},
{
"db_name": "UniProt",
"db_id": "P00046"
},
{
"db_name": "UniProt",
"db_id": "P00047"
},
{
"db_name": "UniProt",
"db_id": "P00048"
},
{
"db_name": "UniProt",
"db_id": "P00049"
},
{
"db_name": "UniProt",
"db_id": "P00051"
},
{
"db_name": "UniProt",
"db_id": "P00052"
},
{
"db_name": "UniProt",
"db_id": "P00053"
},
{
"db_name": "UniProt",
"db_id": "P00054"
},
{
"db_name": "UniProt",
"db_id": "P00055"
},
{
"db_name": "UniProt",
"db_id": "P00056"
},
{
"db_name": "UniProt",
"db_id": "P00057"
},
{
"db_name": "UniProt",
"db_id": "P00058"
},
{
"db_name": "UniProt",
"db_id": "P00059"
},
{
"db_name": "UniProt",
"db_id": "P00060"
},
{
"db_name": "UniProt",
"db_id": "P00061"
},
{
"db_name": "UniProt",
"db_id": "P00062"
},
{
"db_name": "UniProt",
"db_id": "P00063"
},
{
"db_name": "UniProt",
"db_id": "P00064"
},
{
"db_name": "UniProt",
"db_id": "P00065"
},
{
"db_name": "UniProt",
"db_id": "P00066"
},
{
"db_name": "UniProt",
"db_id": "P00067"
},
{
"db_name": "UniProt",
"db_id": "P00068"
},
{
"db_name": "UniProt",
"db_id": "P00069"
},
{
"db_name": "UniProt",
"db_id": "P00070"
},
{
"db_name": "UniProt",
"db_id": "P00071"
},
{
"db_name": "UniProt",
"db_id": "P00072"
},
{
"db_name": "UniProt",
"db_id": "P00073"
},
{
"db_name": "UniProt",
"db_id": "P00074"
},
{
"db_name": "UniProt",
"db_id": "P00075"
},
{
"db_name": "UniProt",
"db_id": "P00076"
},
{
"db_name": "UniProt",
"db_id": "P00077"
},
{
"db_name": "UniProt",
"db_id": "P00078"
},
{
"db_name": "UniProt",
"db_id": "P00079"
},
{
"db_name": "UniProt",
"db_id": "P12831"
},
{
"db_name": "UniProt",
"db_id": "P15451"
},
{
"db_name": "UniProt",
"db_id": "P18822"
},
{
"db_name": "UniProt",
"db_id": "P19681"
},
{
"db_name": "UniProt",
"db_id": "P19974"
},
{
"db_name": "UniProt",
"db_id": "P21665"
},
{
"db_name": "UniProt",
"db_id": "P22342"
},
{
"db_name": "UniProt",
"db_id": "P25400"
},
{
"db_name": "UniProt",
"db_id": "P29380"
},
{
"db_name": "UniProt",
"db_id": "P32556"
},
{
"db_name": "UniProt",
"db_id": "P38091"
},
{
"db_name": "UniProt",
"db_id": "P53698"
},
{
"db_name": "UniProt",
"db_id": "P56205"
},
{
"db_name": "UniProt",
"db_id": "P59218"
},
{
"db_name": "UniProt",
"db_id": "P62772"
},
{
"db_name": "UniProt",
"db_id": "P62773"
},
{
"db_name": "UniProt",
"db_id": "P62894"
},
{
"db_name": "UniProt",
"db_id": "P62895"
},
{
"db_name": "UniProt",
"db_id": "P62896"
},
{
"db_name": "UniProt",
"db_id": "P67881"
},
{
"db_name": "UniProt",
"db_id": "P67882"
},
{
"db_name": "UniProt",
"db_id": "P68096"
},
{
"db_name": "UniProt",
"db_id": "P68097"
},
{
"db_name": "UniProt",
"db_id": "P68098"
},
{
"db_name": "UniProt",
"db_id": "P68099"
},
{
"db_name": "UniProt",
"db_id": "P68100"
},
{
"db_name": "UniProt",
"db_id": "P68517"
},
{
"db_name": "UniProt",
"db_id": "P68518"
},
{
"db_name": "UniProt",
"db_id": "P68519"
},
{
"db_name": "UniProt",
"db_id": "P81280"
},
{
"db_name": "UniProt",
"db_id": "P81459"
},
{
"db_name": "UniProt",
"db_id": "P99998"
},
{
"db_name": "UniProt",
"db_id": "P99999"
},
{
"db_name": "UniProt",
"db_id": "Q41346"
},
{
"db_name": "UniProt",
"db_id": "Q4HVX7"
},
{
"db_name": "UniProt",
"db_id": "Q52V08"
},
{
"db_name": "UniProt",
"db_id": "Q52V09"
},
{
"db_name": "UniProt",
"db_id": "Q52V10"
},
{
"db_name": "UniProt",
"db_id": "Q5RFH4"
},
{
"db_name": "UniProt",
"db_id": "Q640U4"
},
{
"db_name": "UniProt",
"db_id": "Q6C9Q0"
},
{
"db_name": "UniProt",
"db_id": "Q6IQM2"
},
{
"db_name": "UniProt",
"db_id": "Q6Q4H8"
},
{
"db_name": "UniProt",
"db_id": "Q6QLW4"
},
{
"db_name": "UniProt",
"db_id": "Q6WUX8"
},
{
"db_name": "UniProt",
"db_id": "Q753F4"
},
{
"db_name": "UniProt",
"db_id": "Q7YR71"
},
{
"db_name": "UniProt",
"db_id": "Q96VP3"
}
]
},
{
"id": "DS.d57.s0.e1",
"type": "compound",
"text": [
"RU486"
],
"offsets": [
[
160,
165
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "55245"
}
]
}
] | [] | [] | [
{
"id": "DS.d57.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d57.s0.e1",
"arg2_id": "DS.d57.s0.e0",
"normalized": []
}
] |
DS.d58 | 18256928 | [
{
"id": "DS.d58.s0",
"text": [
"Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model."
],
"offsets": [
[
0,
127
]
],
"type": ""
},
{
"id": "DS.d58.s1",
"text": [
"However, when ERalpha negative MDA-MB-435 cells were treated with metformin, they demonstrated increased expression of vascular endothelial growth factor (VEGF) in an AMPK dependent manner; while the ERalpha positive MCF-7 cells did not."
],
"offsets": [
[
128,
365
]
],
"type": ""
},
{
"id": "DS.d58.s2",
"text": [
"The metformin-treated group showed increased VEGF expression, intratumoral microvascular density and reduced necrosis."
],
"offsets": [
[
366,
484
]
],
"type": ""
},
{
"id": "DS.d58.s3",
"text": [
"Metformin treatment was sufficient, however, to reduce systemic IGF-1 and the proliferation rate of tumor cells in vascularized regions."
],
"offsets": [
[
485,
621
]
],
"type": ""
}
] | [
{
"id": "DS.d58.s0.e0",
"type": "compound",
"text": [
"metformin"
],
"offsets": [
[
12,
21
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4091"
}
]
},
{
"id": "DS.d58.s0.e1",
"type": "protein",
"text": [
"AMPK"
],
"offsets": [
[
22,
26
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P54646"
},
{
"db_name": "UniProt",
"db_id": "Q09136"
},
{
"db_name": "UniProt",
"db_id": "Q9Y478"
}
]
},
{
"id": "DS.d58.s1.e0",
"type": "compound",
"text": [
"metformin"
],
"offsets": [
[
194,
203
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4091"
}
]
},
{
"id": "DS.d58.s1.e1",
"type": "protein",
"text": [
"VEGF"
],
"offsets": [
[
283,
287
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P15691"
},
{
"db_name": "UniProt",
"db_id": "P15692"
},
{
"db_name": "UniProt",
"db_id": "P26617"
},
{
"db_name": "UniProt",
"db_id": "P49151"
},
{
"db_name": "UniProt",
"db_id": "P50412"
},
{
"db_name": "UniProt",
"db_id": "P67964"
},
{
"db_name": "UniProt",
"db_id": "P67965"
},
{
"db_name": "UniProt",
"db_id": "Q99PS1"
},
{
"db_name": "UniProt",
"db_id": "Q9GKR0"
},
{
"db_name": "UniProt",
"db_id": "Q9MYV3"
}
]
},
{
"id": "DS.d58.s1.e2",
"type": "protein",
"text": [
"AMPK"
],
"offsets": [
[
295,
299
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P54646"
},
{
"db_name": "UniProt",
"db_id": "Q09136"
},
{
"db_name": "UniProt",
"db_id": "Q9Y478"
}
]
},
{
"id": "DS.d58.s2.e0",
"type": "compound",
"text": [
"metformin"
],
"offsets": [
[
370,
379
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4091"
}
]
},
{
"id": "DS.d58.s2.e1",
"type": "protein",
"text": [
"VEGF"
],
"offsets": [
[
411,
415
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P15691"
},
{
"db_name": "UniProt",
"db_id": "P15692"
},
{
"db_name": "UniProt",
"db_id": "P26617"
},
{
"db_name": "UniProt",
"db_id": "P49151"
},
{
"db_name": "UniProt",
"db_id": "P50412"
},
{
"db_name": "UniProt",
"db_id": "P67964"
},
{
"db_name": "UniProt",
"db_id": "P67965"
},
{
"db_name": "UniProt",
"db_id": "Q99PS1"
},
{
"db_name": "UniProt",
"db_id": "Q9GKR0"
},
{
"db_name": "UniProt",
"db_id": "Q9MYV3"
}
]
},
{
"id": "DS.d58.s3.e0",
"type": "compound",
"text": [
"Metformin"
],
"offsets": [
[
485,
494
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "4091"
}
]
},
{
"id": "DS.d58.s3.e1",
"type": "protein",
"text": [
"IGF-1"
],
"offsets": [
[
549,
554
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q95222"
}
]
}
] | [] | [] | [
{
"id": "DS.d58.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d58.s0.e0",
"arg2_id": "DS.d58.s0.e1",
"normalized": []
},
{
"id": "DS.d58.s1.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d58.s1.e0",
"arg2_id": "DS.d58.s1.e2",
"normalized": []
},
{
"id": "DS.d58.s1.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d58.s1.e0",
"arg2_id": "DS.d58.s1.e1",
"normalized": []
},
{
"id": "DS.d58.s2.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d58.s2.e0",
"arg2_id": "DS.d58.s2.e1",
"normalized": []
},
{
"id": "DS.d58.s3.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d58.s3.e0",
"arg2_id": "DS.d58.s3.e1",
"normalized": []
}
] |
DS.d59 | 18260130 | [
{
"id": "DS.d59.s0",
"text": [
"TNF-alpha, MCP-1, MIP-1alpha, IL-8, IL-6, IL-1beta, VEGF, IL-1ra, and IL-10 were measured from monocyte/macrophage cultures at different stages of activation and differentiation seeded onto polyethylene, polyurethane, expanded polytetrafluoroethylene, polymethyl methacrylate, and a hydrogel copolymer of 2-hydroxyethyl methacrylate, 1-vinyl-2-pyrrolidinone, and polyethylene glycol acrylate in tissue culture polystyrene (TCPS) plates."
],
"offsets": [
[
0,
436
]
],
"type": ""
}
] | [
{
"id": "DS.d59.s0.e0",
"type": "protein",
"text": [
"TNF-alpha"
],
"offsets": [
[
0,
9
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35734"
},
{
"db_name": "UniProt",
"db_id": "O77510"
},
{
"db_name": "UniProt",
"db_id": "O77764"
},
{
"db_name": "UniProt",
"db_id": "P01375"
},
{
"db_name": "UniProt",
"db_id": "P04924"
},
{
"db_name": "UniProt",
"db_id": "P06804"
},
{
"db_name": "UniProt",
"db_id": "P13296"
},
{
"db_name": "UniProt",
"db_id": "P16599"
},
{
"db_name": "UniProt",
"db_id": "P19101"
},
{
"db_name": "UniProt",
"db_id": "P23383"
},
{
"db_name": "UniProt",
"db_id": "P23563"
},
{
"db_name": "UniProt",
"db_id": "P29553"
},
{
"db_name": "UniProt",
"db_id": "P33620"
},
{
"db_name": "UniProt",
"db_id": "P36939"
},
{
"db_name": "UniProt",
"db_id": "P48094"
},
{
"db_name": "UniProt",
"db_id": "P51435"
},
{
"db_name": "UniProt",
"db_id": "P51742"
},
{
"db_name": "UniProt",
"db_id": "P51743"
},
{
"db_name": "UniProt",
"db_id": "P59684"
},
{
"db_name": "UniProt",
"db_id": "P59693"
},
{
"db_name": "UniProt",
"db_id": "P59694"
},
{
"db_name": "UniProt",
"db_id": "P59695"
},
{
"db_name": "UniProt",
"db_id": "P79337"
},
{
"db_name": "UniProt",
"db_id": "P79374"
},
{
"db_name": "UniProt",
"db_id": "Q06599"
},
{
"db_name": "UniProt",
"db_id": "Q19LH4"
},
{
"db_name": "UniProt",
"db_id": "Q1G1A2"
},
{
"db_name": "UniProt",
"db_id": "Q1WM27"
},
{
"db_name": "UniProt",
"db_id": "Q2MH05"
},
{
"db_name": "UniProt",
"db_id": "Q539C2"
},
{
"db_name": "UniProt",
"db_id": "Q75N23"
},
{
"db_name": "UniProt",
"db_id": "Q8HZD9"
},
{
"db_name": "UniProt",
"db_id": "Q8JFG3"
},
{
"db_name": "UniProt",
"db_id": "Q8MKG8"
},
{
"db_name": "UniProt",
"db_id": "Q8WNR1"
},
{
"db_name": "UniProt",
"db_id": "Q9BEA1"
}
]
},
{
"id": "DS.d59.s0.e1",
"type": "protein",
"text": [
"MCP-1"
],
"offsets": [
[
11,
16
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10148"
},
{
"db_name": "UniProt",
"db_id": "P13500"
},
{
"db_name": "UniProt",
"db_id": "P14844"
},
{
"db_name": "UniProt",
"db_id": "P28291"
},
{
"db_name": "UniProt",
"db_id": "P28292"
},
{
"db_name": "UniProt",
"db_id": "P42831"
},
{
"db_name": "UniProt",
"db_id": "P52203"
},
{
"db_name": "UniProt",
"db_id": "P61274"
},
{
"db_name": "UniProt",
"db_id": "P61275"
},
{
"db_name": "UniProt",
"db_id": "Q08782"
},
{
"db_name": "UniProt",
"db_id": "Q9TTQ3"
}
]
},
{
"id": "DS.d59.s0.e2",
"type": "protein",
"text": [
"MIP-1alpha"
],
"offsets": [
[
18,
28
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P10147"
},
{
"db_name": "UniProt",
"db_id": "P10855"
},
{
"db_name": "UniProt",
"db_id": "P50229"
},
{
"db_name": "UniProt",
"db_id": "Q5I1Z0"
},
{
"db_name": "UniProt",
"db_id": "Q8HYQ3"
},
{
"db_name": "UniProt",
"db_id": "Q8SQA6"
}
]
},
{
"id": "DS.d59.s0.e3",
"type": "protein",
"text": [
"IL-8"
],
"offsets": [
[
30,
34
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62812"
},
{
"db_name": "UniProt",
"db_id": "P08317"
},
{
"db_name": "UniProt",
"db_id": "P10145"
},
{
"db_name": "UniProt",
"db_id": "P19874"
},
{
"db_name": "UniProt",
"db_id": "P26894"
},
{
"db_name": "UniProt",
"db_id": "P36925"
},
{
"db_name": "UniProt",
"db_id": "P41324"
},
{
"db_name": "UniProt",
"db_id": "P46653"
},
{
"db_name": "UniProt",
"db_id": "P49113"
},
{
"db_name": "UniProt",
"db_id": "P67813"
},
{
"db_name": "UniProt",
"db_id": "P67814"
},
{
"db_name": "UniProt",
"db_id": "P79255"
},
{
"db_name": "UniProt",
"db_id": "Q102R3"
},
{
"db_name": "UniProt",
"db_id": "Q7YRB5"
},
{
"db_name": "UniProt",
"db_id": "Q9XSX5"
}
]
},
{
"id": "DS.d59.s0.e4",
"type": "protein",
"text": [
"IL-6"
],
"offsets": [
[
36,
40
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O35736"
},
{
"db_name": "UniProt",
"db_id": "P05231"
},
{
"db_name": "UniProt",
"db_id": "P08505"
},
{
"db_name": "UniProt",
"db_id": "P20607"
},
{
"db_name": "UniProt",
"db_id": "P26892"
},
{
"db_name": "UniProt",
"db_id": "P26893"
},
{
"db_name": "UniProt",
"db_id": "P29455"
},
{
"db_name": "UniProt",
"db_id": "P41323"
},
{
"db_name": "UniProt",
"db_id": "P41683"
},
{
"db_name": "UniProt",
"db_id": "P41693"
},
{
"db_name": "UniProt",
"db_id": "P46650"
},
{
"db_name": "UniProt",
"db_id": "P51494"
},
{
"db_name": "UniProt",
"db_id": "P79341"
},
{
"db_name": "UniProt",
"db_id": "Q25BC2"
},
{
"db_name": "UniProt",
"db_id": "Q28319"
},
{
"db_name": "UniProt",
"db_id": "Q28747"
},
{
"db_name": "UniProt",
"db_id": "Q28819"
},
{
"db_name": "UniProt",
"db_id": "Q2MH06"
},
{
"db_name": "UniProt",
"db_id": "Q5I6E3"
},
{
"db_name": "UniProt",
"db_id": "Q6V919"
},
{
"db_name": "UniProt",
"db_id": "Q865W7"
},
{
"db_name": "UniProt",
"db_id": "Q865X6"
},
{
"db_name": "UniProt",
"db_id": "Q8MKH0"
},
{
"db_name": "UniProt",
"db_id": "Q95181"
},
{
"db_name": "UniProt",
"db_id": "Q9MZR1"
},
{
"db_name": "UniProt",
"db_id": "Q9XT80"
}
]
},
{
"id": "DS.d59.s0.e5",
"type": "protein",
"text": [
"IL-1beta"
],
"offsets": [
[
42,
50
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P01584"
},
{
"db_name": "UniProt",
"db_id": "P09428"
},
{
"db_name": "UniProt",
"db_id": "P10749"
},
{
"db_name": "UniProt",
"db_id": "P14628"
},
{
"db_name": "UniProt",
"db_id": "P21621"
},
{
"db_name": "UniProt",
"db_id": "P26889"
},
{
"db_name": "UniProt",
"db_id": "P41687"
},
{
"db_name": "UniProt",
"db_id": "P46648"
},
{
"db_name": "UniProt",
"db_id": "P48090"
},
{
"db_name": "UniProt",
"db_id": "P51493"
},
{
"db_name": "UniProt",
"db_id": "P51745"
},
{
"db_name": "UniProt",
"db_id": "P79162"
},
{
"db_name": "UniProt",
"db_id": "P79182"
},
{
"db_name": "UniProt",
"db_id": "Q28292"
},
{
"db_name": "UniProt",
"db_id": "Q28386"
},
{
"db_name": "UniProt",
"db_id": "Q2HZH0"
},
{
"db_name": "UniProt",
"db_id": "Q2MH07"
},
{
"db_name": "UniProt",
"db_id": "Q63264"
},
{
"db_name": "UniProt",
"db_id": "Q6PUD2"
},
{
"db_name": "UniProt",
"db_id": "Q6R2X3"
},
{
"db_name": "UniProt",
"db_id": "Q865X8"
},
{
"db_name": "UniProt",
"db_id": "Q8WNR2"
},
{
"db_name": "UniProt",
"db_id": "Q9WVG1"
},
{
"db_name": "UniProt",
"db_id": "Q9XS77"
}
]
},
{
"id": "DS.d59.s0.e6",
"type": "protein",
"text": [
"VEGF"
],
"offsets": [
[
52,
56
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P15691"
},
{
"db_name": "UniProt",
"db_id": "P15692"
},
{
"db_name": "UniProt",
"db_id": "P26617"
},
{
"db_name": "UniProt",
"db_id": "P49151"
},
{
"db_name": "UniProt",
"db_id": "P50412"
},
{
"db_name": "UniProt",
"db_id": "P67964"
},
{
"db_name": "UniProt",
"db_id": "P67965"
},
{
"db_name": "UniProt",
"db_id": "Q99PS1"
},
{
"db_name": "UniProt",
"db_id": "Q9GKR0"
},
{
"db_name": "UniProt",
"db_id": "Q9MYV3"
}
]
},
{
"id": "DS.d59.s0.e7",
"type": "protein",
"text": [
"IL-1ra"
],
"offsets": [
[
58,
64
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O18999"
},
{
"db_name": "UniProt",
"db_id": "O77482"
},
{
"db_name": "UniProt",
"db_id": "P18510"
},
{
"db_name": "UniProt",
"db_id": "P25085"
},
{
"db_name": "UniProt",
"db_id": "P25086"
},
{
"db_name": "UniProt",
"db_id": "P26890"
},
{
"db_name": "UniProt",
"db_id": "Q29056"
},
{
"db_name": "UniProt",
"db_id": "Q866R8"
},
{
"db_name": "UniProt",
"db_id": "Q9BEH0"
},
{
"db_name": "UniProt",
"db_id": "Q9GMZ4"
}
]
},
{
"id": "DS.d59.s0.e8",
"type": "protein",
"text": [
"IL-10"
],
"offsets": [
[
70,
75
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O46673"
},
{
"db_name": "UniProt",
"db_id": "O97798"
},
{
"db_name": "UniProt",
"db_id": "P18893"
},
{
"db_name": "UniProt",
"db_id": "P22301"
},
{
"db_name": "UniProt",
"db_id": "P29456"
},
{
"db_name": "UniProt",
"db_id": "P43480"
},
{
"db_name": "UniProt",
"db_id": "P46651"
},
{
"db_name": "UniProt",
"db_id": "P47965"
},
{
"db_name": "UniProt",
"db_id": "P48411"
},
{
"db_name": "UniProt",
"db_id": "P51496"
},
{
"db_name": "UniProt",
"db_id": "P51497"
},
{
"db_name": "UniProt",
"db_id": "P51746"
},
{
"db_name": "UniProt",
"db_id": "P55029"
},
{
"db_name": "UniProt",
"db_id": "P79338"
},
{
"db_name": "UniProt",
"db_id": "Q0Z972"
},
{
"db_name": "UniProt",
"db_id": "Q25BC1"
},
{
"db_name": "UniProt",
"db_id": "Q28374"
},
{
"db_name": "UniProt",
"db_id": "Q29055"
},
{
"db_name": "UniProt",
"db_id": "Q29408"
},
{
"db_name": "UniProt",
"db_id": "Q2PE73"
},
{
"db_name": "UniProt",
"db_id": "Q5Q0V6"
},
{
"db_name": "UniProt",
"db_id": "Q865X4"
},
{
"db_name": "UniProt",
"db_id": "Q8MKG9"
},
{
"db_name": "UniProt",
"db_id": "Q9JHK7"
},
{
"db_name": "UniProt",
"db_id": "Q9TSJ4"
},
{
"db_name": "UniProt",
"db_id": "Q9Z1Y5"
}
]
},
{
"id": "DS.d59.s0.e9",
"type": "compound",
"text": [
"polyurethane"
],
"offsets": [
[
204,
216
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "12254"
}
]
},
{
"id": "DS.d59.s0.e10",
"type": "compound",
"text": [
"polymethyl methacrylate"
],
"offsets": [
[
252,
275
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6658"
}
]
},
{
"id": "DS.d59.s0.e11",
"type": "compound",
"text": [
"2-hydroxyethyl methacrylate"
],
"offsets": [
[
305,
332
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "13360"
}
]
},
{
"id": "DS.d59.s0.e12",
"type": "compound",
"text": [
"1-vinyl-2-pyrrolidinone"
],
"offsets": [
[
334,
357
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6917"
}
]
},
{
"id": "DS.d59.s0.e13",
"type": "compound",
"text": [
"polystyrene"
],
"offsets": [
[
410,
421
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "7501"
}
]
}
] | [] | [] | [] |
DS.d60 | 18262559 | [
{
"id": "DS.d60.s0",
"text": [
"Systemic administration of hemoglobin vesicle elevates tumor tissue oxygen tension and modifies tumor response to irradiation."
],
"offsets": [
[
0,
126
]
],
"type": ""
}
] | [
{
"id": "DS.d60.s0.e0",
"type": "protein",
"text": [
"hemoglobin"
],
"offsets": [
[
27,
37
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P15160"
},
{
"db_name": "UniProt",
"db_id": "P17724"
},
{
"db_name": "UniProt",
"db_id": "P73925"
},
{
"db_name": "UniProt",
"db_id": "Q03459"
}
]
},
{
"id": "DS.d60.s0.e1",
"type": "compound",
"text": [
"oxygen"
],
"offsets": [
[
68,
74
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "977"
}
]
}
] | [] | [] | [
{
"id": "DS.d60.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d60.s0.e1",
"arg2_id": "DS.d60.s0.e0",
"normalized": []
}
] |
DS.d61 | 18262738 | [
{
"id": "DS.d61.s0",
"text": [
"The participation of protein kinase A (PKA), protein kinase C (PKC) and protein tyrosine kinase (PTK) in capacitation induced by ONOO (-) was evaluated by incubation with specific inhibitors (50 microM H-89, 0.1 microM bisindolylmaleimide I, and 3 microM genistein, respectively)."
],
"offsets": [
[
0,
280
]
],
"type": ""
}
] | [
{
"id": "DS.d61.s0.e0",
"type": "protein",
"text": [
"protein kinase A"
],
"offsets": [
[
21,
37
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q05608"
},
{
"db_name": "UniProt",
"db_id": "Q9RI12"
}
]
},
{
"id": "DS.d61.s0.e1",
"type": "protein",
"text": [
"protein kinase C"
],
"offsets": [
[
45,
61
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P13678"
},
{
"db_name": "UniProt",
"db_id": "Q25378"
}
]
},
{
"id": "DS.d61.s0.e2",
"type": "protein",
"text": [
"PKC"
],
"offsets": [
[
63,
66
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "P05130"
},
{
"db_name": "UniProt",
"db_id": "P13677"
},
{
"db_name": "UniProt",
"db_id": "P13678"
},
{
"db_name": "UniProt",
"db_id": "P34722"
}
]
},
{
"id": "DS.d61.s0.e3",
"type": "compound",
"text": [
"ONOO"
],
"offsets": [
[
129,
133
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5460609"
}
]
},
{
"id": "DS.d61.s0.e4",
"type": "compound",
"text": [
"bisindolylmaleimide I"
],
"offsets": [
[
219,
240
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "2396"
}
]
},
{
"id": "DS.d61.s0.e5",
"type": "compound",
"text": [
"genistein"
],
"offsets": [
[
255,
264
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "5280961"
}
]
}
] | [] | [] | [] |
DS.d62 | 18266054 | [
{
"id": "DS.d62.s0",
"text": [
"At the time, glutathione reductase activity was significantly inhibited and gamma-glutamyl cysteine increased by ACA exposure."
],
"offsets": [
[
0,
126
]
],
"type": ""
}
] | [
{
"id": "DS.d62.s0.e0",
"type": "protein",
"text": [
"glutathione reductase"
],
"offsets": [
[
13,
34
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O15770"
},
{
"db_name": "UniProt",
"db_id": "P06715"
},
{
"db_name": "UniProt",
"db_id": "P11804"
},
{
"db_name": "UniProt",
"db_id": "P23189"
},
{
"db_name": "UniProt",
"db_id": "P41921"
},
{
"db_name": "UniProt",
"db_id": "P43783"
},
{
"db_name": "UniProt",
"db_id": "P48638"
},
{
"db_name": "UniProt",
"db_id": "P48639"
},
{
"db_name": "UniProt",
"db_id": "P70619"
},
{
"db_name": "UniProt",
"db_id": "P78965"
},
{
"db_name": "UniProt",
"db_id": "Q60151"
},
{
"db_name": "UniProt",
"db_id": "Q6BPI1"
},
{
"db_name": "UniProt",
"db_id": "Q6C5H4"
},
{
"db_name": "UniProt",
"db_id": "Q6FRV2"
},
{
"db_name": "UniProt",
"db_id": "Q6HA23"
},
{
"db_name": "UniProt",
"db_id": "Q74ZK4"
},
{
"db_name": "UniProt",
"db_id": "Q873E8"
},
{
"db_name": "UniProt",
"db_id": "Q94655"
}
]
},
{
"id": "DS.d62.s0.e1",
"type": "compound",
"text": [
"cysteine"
],
"offsets": [
[
91,
99
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "594"
},
{
"db_name": "PubChem",
"db_id": "5862"
},
{
"db_name": "PubChem",
"db_id": "5360637"
}
]
}
] | [] | [] | [] |
DS.d63 | 18268501 | [
{
"id": "DS.d63.s0",
"text": [
"The effect of the polymorphism is non-conservative and results in a glutamine to arginine change (Gln460Arg), which is likely to affect P2RX7 dimerization and protein-protein interactions."
],
"offsets": [
[
0,
188
]
],
"type": ""
}
] | [
{
"id": "DS.d63.s0.e0",
"type": "compound",
"text": [
"glutamine"
],
"offsets": [
[
68,
77
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "738"
},
{
"db_name": "PubChem",
"db_id": "5961"
}
]
},
{
"id": "DS.d63.s0.e1",
"type": "compound",
"text": [
"arginine"
],
"offsets": [
[
81,
89
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "232"
},
{
"db_name": "PubChem",
"db_id": "4367"
},
{
"db_name": "PubChem",
"db_id": "6322"
}
]
},
{
"id": "DS.d63.s0.e2",
"type": "protein",
"text": [
"P2RX7"
],
"offsets": [
[
136,
141
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q99572"
}
]
}
] | [] | [] | [
{
"id": "DS.d63.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d63.s0.e1",
"arg2_id": "DS.d63.s0.e2",
"normalized": []
},
{
"id": "DS.d63.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d63.s0.e0",
"arg2_id": "DS.d63.s0.e2",
"normalized": []
}
] |
DS.d64 | 18270841 | [
{
"id": "DS.d64.s0",
"text": [
"Increased somatostatin tone and decreased ghrelin concentrations may also contribute to reduced GH levels."
],
"offsets": [
[
0,
106
]
],
"type": ""
}
] | [
{
"id": "DS.d64.s0.e0",
"type": "compound",
"text": [
"somatostatin"
],
"offsets": [
[
10,
22
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "16129681"
},
{
"db_name": "PubChem",
"db_id": "16129706"
}
]
},
{
"id": "DS.d64.s0.e1",
"type": "protein",
"text": [
"ghrelin"
],
"offsets": [
[
42,
49
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "Q6BEG6"
},
{
"db_name": "UniProt",
"db_id": "Q6BEG7"
},
{
"db_name": "UniProt",
"db_id": "Q9BDJ6"
},
{
"db_name": "UniProt",
"db_id": "Q9BEF8"
},
{
"db_name": "UniProt",
"db_id": "Q9EQX0"
},
{
"db_name": "UniProt",
"db_id": "Q9GKY5"
},
{
"db_name": "UniProt",
"db_id": "Q9QYH7"
},
{
"db_name": "UniProt",
"db_id": "Q9UBU3"
}
]
}
] | [] | [] | [] |
DS.d65 | 18272254 | [
{
"id": "DS.d65.s0",
"text": [
"Inhibition of LTP by beta-amyloid is prevented by activation of beta2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway."
],
"offsets": [
[
0,
135
]
],
"type": ""
}
] | [
{
"id": "DS.d65.s0.e0",
"type": "protein",
"text": [
"beta2 adrenoceptors"
],
"offsets": [
[
64,
83
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O70431"
},
{
"db_name": "UniProt",
"db_id": "P04274"
},
{
"db_name": "UniProt",
"db_id": "P07550"
},
{
"db_name": "UniProt",
"db_id": "P10608"
},
{
"db_name": "UniProt",
"db_id": "P18762"
},
{
"db_name": "UniProt",
"db_id": "P54833"
},
{
"db_name": "UniProt",
"db_id": "Q28044"
},
{
"db_name": "UniProt",
"db_id": "Q28509"
},
{
"db_name": "UniProt",
"db_id": "Q28997"
},
{
"db_name": "UniProt",
"db_id": "Q4KWL2"
},
{
"db_name": "UniProt",
"db_id": "Q8UUY8"
},
{
"db_name": "UniProt",
"db_id": "Q9TST5"
}
]
},
{
"id": "DS.d65.s0.e1",
"type": "compound",
"text": [
"cAMP"
],
"offsets": [
[
107,
111
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "6076"
}
]
}
] | [] | [] | [] |
DS.d66 | 18274872 | [
{
"id": "DS.d66.s0",
"text": [
") O2 (-) and H2O2 in H. plumaeforme was respectively related to the low activity of SOD and the decreased activity of CAT."
],
"offsets": [
[
0,
122
]
],
"type": ""
}
] | [
{
"id": "DS.d66.s0.e0",
"type": "compound",
"text": [
"O2"
],
"offsets": [
[
2,
4
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "977"
},
{
"db_name": "PubChem",
"db_id": "5359597"
}
]
},
{
"id": "DS.d66.s0.e1",
"type": "compound",
"text": [
"H2O2"
],
"offsets": [
[
13,
17
]
],
"normalized": [
{
"db_name": "PubChem",
"db_id": "784"
}
]
},
{
"id": "DS.d66.s0.e2",
"type": "protein",
"text": [
"SOD"
],
"offsets": [
[
84,
87
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O12933"
},
{
"db_name": "UniProt",
"db_id": "O22668"
},
{
"db_name": "UniProt",
"db_id": "O75007"
},
{
"db_name": "UniProt",
"db_id": "P24705"
},
{
"db_name": "UniProt",
"db_id": "P51547"
},
{
"db_name": "UniProt",
"db_id": "P93258"
},
{
"db_name": "UniProt",
"db_id": "Q01137"
},
{
"db_name": "UniProt",
"db_id": "Q27666"
},
{
"db_name": "UniProt",
"db_id": "Q9SM64"
}
]
},
{
"id": "DS.d66.s0.e3",
"type": "protein",
"text": [
"CAT"
],
"offsets": [
[
118,
121
]
],
"normalized": [
{
"db_name": "UniProt",
"db_id": "O62839"
},
{
"db_name": "UniProt",
"db_id": "O97492"
},
{
"db_name": "UniProt",
"db_id": "P00432"
},
{
"db_name": "UniProt",
"db_id": "P00485"
},
{
"db_name": "UniProt",
"db_id": "P00486"
},
{
"db_name": "UniProt",
"db_id": "P00487"
},
{
"db_name": "UniProt",
"db_id": "P04040"
},
{
"db_name": "UniProt",
"db_id": "P06135"
},
{
"db_name": "UniProt",
"db_id": "P07641"
},
{
"db_name": "UniProt",
"db_id": "P11504"
},
{
"db_name": "UniProt",
"db_id": "P20074"
},
{
"db_name": "UniProt",
"db_id": "P22782"
},
{
"db_name": "UniProt",
"db_id": "P25309"
},
{
"db_name": "UniProt",
"db_id": "P25819"
},
{
"db_name": "UniProt",
"db_id": "P26825"
},
{
"db_name": "UniProt",
"db_id": "P26826"
},
{
"db_name": "UniProt",
"db_id": "P32796"
},
{
"db_name": "UniProt",
"db_id": "P36882"
},
{
"db_name": "UniProt",
"db_id": "P36883"
},
{
"db_name": "UniProt",
"db_id": "P43155"
},
{
"db_name": "UniProt",
"db_id": "P47934"
},
{
"db_name": "UniProt",
"db_id": "P49417"
},
{
"db_name": "UniProt",
"db_id": "P52826"
},
{
"db_name": "UniProt",
"db_id": "P58777"
},
{
"db_name": "UniProt",
"db_id": "P62577"
},
{
"db_name": "UniProt",
"db_id": "P62578"
},
{
"db_name": "UniProt",
"db_id": "P62579"
},
{
"db_name": "UniProt",
"db_id": "P62580"
},
{
"db_name": "UniProt",
"db_id": "P90682"
},
{
"db_name": "UniProt",
"db_id": "Q00614"
},
{
"db_name": "UniProt",
"db_id": "Q02736"
},
{
"db_name": "UniProt",
"db_id": "Q03058"
},
{
"db_name": "UniProt",
"db_id": "Q5RF10"
},
{
"db_name": "UniProt",
"db_id": "Q64405"
},
{
"db_name": "UniProt",
"db_id": "Q704S8"
},
{
"db_name": "UniProt",
"db_id": "Q9M5L6"
},
{
"db_name": "UniProt",
"db_id": "Q9PWF7"
}
]
}
] | [] | [] | [
{
"id": "DS.d66.s0.i0",
"type": "compound-protein-interaction",
"arg1_id": "DS.d66.s0.e0",
"arg2_id": "DS.d66.s0.e2",
"normalized": []
},
{
"id": "DS.d66.s0.i1",
"type": "compound-protein-interaction",
"arg1_id": "DS.d66.s0.e1",
"arg2_id": "DS.d66.s0.e3",
"normalized": []
},
{
"id": "DS.d66.s0.i2",
"type": "compound-protein-interaction",
"arg1_id": "DS.d66.s0.e1",
"arg2_id": "DS.d66.s0.e2",
"normalized": []
},
{
"id": "DS.d66.s0.i3",
"type": "compound-protein-interaction",
"arg1_id": "DS.d66.s0.e0",
"arg2_id": "DS.d66.s0.e3",
"normalized": []
}
] |
End of preview. Expand
in Dataset Viewer.
Dataset Card for CPI
The compound-protein relationship (CPI) dataset consists of 2,613 sentences from abstracts containing annotations of proteins, small molecules, and their relationships.
Citation Information
@article{doring2020automated,
title={Automated recognition of functional compound-protein relationships in literature},
author={D{\"o}ring, Kersten and Qaseem, Ammar and Becer, Michael and Li, Jianyu and Mishra, Pankaj and Gao, Mingjie and Kirchner, Pascal and Sauter, Florian and Telukunta, Kiran K and Moumbock, Aur{\'e}lien FA and others},
journal={Plos one},
volume={15},
number={3},
pages={e0220925},
year={2020},
publisher={Public Library of Science San Francisco, CA USA}
}
- Downloads last month
- 56