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BigScience Biomedical Datasets 141

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Care in the succeeding days included analgesia, antibiotics, and high-calorie dietary supplementation as described previously (Chen et al. 1996, 1999, 2014; Chen and Wolpaw 2002).

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GHLab is a software that utilizes shifts in acceleration to define time events according to the Dynamic Adaptive Piston Pump (DAPP) principle describing the heart as a mechanical pump controlled by its inflow [23].

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We make use of Naive Bayes [14] and Support Vector Machine classifiers for these experiments.

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Basal ATP concentrations in the bulk medium of unstimulated CFs are low, but the concentrations of released nucleotides near the cell surface may be sufficient to activate adjacent P2Y receptors and contribute to basal signaling (48, 49).

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In [11], we observed that while the our segment-based speech recognition systems performs well in clean speech, the system has difficulty placing landmarks (representing phonetic transitions) in the presence of noise and often produces poor recognition hypotheses.

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[4] reported that, compared with the syndrome scales, the CBCL DOSs evidenced a similar degree of internal consistency, test–retest reliability, and cross-informant agreement.

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thaliana from the following sources, GenBank [4], FlyBase [6], ExPASy [2,7], HUGO [5], ENSEMBL [3], UCSC [8], and Gene Ontology [9].

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…studies show that colonies of Aurelia spp. polyps are mainly distributed on artificial constructions off the coasts of Japan, the UK, France and the Mediterranean (Miyake et al., 2002; Ishii & Katsukoshi, 2010; Duarte et al., 2012; Malej et al., 2012; Marques et al., 2015; Vodopivec et al., 2017).

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However, the persistence of antibody responses long after malaria transmission has ceased has been reported in a non-endemic region of Brazil and in a low transmission area in Thailand, and long-lived anti-CSP antibody responses have been detected in the absence of a blood-stage infection [25, 26].

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H-type BSE has been described in cattle from France [11], Germany [1], Japan [12], the Netherlands [13], Poland [14], Switzerland [15], the United Kingdom [16], Canada [17], and the United States [18].

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It is well known that platelet adhesion to pFN, mediated by aIIbb3 with contributions from a5b1 and other integrins, plays a critical role for hemostasis (Wang et al., 2014; Ni et al., 2003b).

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In compiling this list we gave consideration to gaining as wide a range of opinion as possible so as to ensure a fair representation of how the implementation of iCCM was experienced in Ghana [36].

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Assuming the well-known Kronecker correlation structure [10–13] we can decompose H as H = R 1 2HwS 1 2 (2) where R and S are the receive and transmit correlation matrices respectively, satisfying tr (R) = Nr and tr (S) = Nt, and the elements of Hw are i.

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Moreover, considering the fact that observers have previously rated the images with higher colorfulness values as being of higher quality [3] we can state that memory color reproduction influences the preferred color reproduction of the objects [14].

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Yet similar to [21], their estimator depends on the approximation of a general graph to tree and also requires the maximum number of sources.

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When growing in a cobalt-deficient medium, degradation rate and growth rate were significantly reduced [35].

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Furthermore, those bands are commonly used in vegetation studies [16–18] and the segmented area consists mainly of different forms of vegetation.

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Such relationships between tissue [N] and two morphological parameters, SRL and tissue density, were also found in some studies with multiple species; for example, the variability of root tissue [N] in herbs and woody plants was strongly associated with tissue density and weakly with SRL (Roumet et al. 2006; Comas and Eissenstat 2009; Kong et al. 2014).

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The speech recognizer that we used for the evaluation was based on a multi-condition convolutional neural network (CNN) acoustic model and a recurrent neural network (RNN) language model [29] in addition to a trigram language model.

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(MEA) reported over-regularization rates for each of 25 children from the CHILDES database of transcripts (MacWhinney, 2000).

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To visualize the organization of the six MBDs at the atomic level, we developed a full-length model of the six MBDs by integrating current structural and biophysical data (Dmitriev et al. 2016; Yu et al. 2017a).

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IETF standardised VoIP is a combination of four predominate standards: RFC3261: Session Initiation Protocol (SIP) [18], RFC2327: Session Description Protocol (SDP) [12], RFC3550: Real-time Transport Protocol (RTP) [19], and later RFC3711: The Secure Real-time Transport Protocol (SRTP) [3].

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Upon initial pulmonary infection, a subset of C. neoformans cells differentiate into enlarged titan cells with a thick cell wall and a highly crosslinked capsule (Feldmesser et al., 2001; Okagaki et al., 2010; Zaragoza et al., 2010).

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The pressure-intercept is fixed at 140 GPa, derived from the inflection pressure of SiO2 glass reported by Murakami and Bass (2010).

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Gene function classification 48 We use single-variable slice sampling (Neal, 2003) to sample from the posterior distribution of hyperparameters.

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The Feasible-Infeasible Two-Population Genetic Algorithm (FI2PopGA) [3, 4, 5, 6, 7] retains infeasible solutions whose evolutionary selection is based on fitness measured as distance from feasibility.

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Ubiquitination of the endocytic machinery may also be essential for endocytosis (64).

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100 million years ago (mya), and duplication of the alcohol dehydrogenase encoding gene and genes encoding hexose transporters [4,11] have been proposed as a possible molecular background for development of Crabtree effect and the ‘‘makeaccumulate-consume’’ strategy in the S.

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Analysis of this partial sex chromosome sequence revealed that the contig contains the previously identified W marker Pv72W and contig C1, but not the Z marker Pv71Z [27,28] (Figure 1a).

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Pulmonary function tests were performed according to the standards of the European Community of Coal and Steel [30].

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…within and 15.20% between assay for 1,25-dihydroxyvitamin D. Proficiency testing was conducted with DEQAS, CAP, API, and NIST for 25-hydroxyvitamin D and with DEQAS and CAP for 1,25-dihydroxyvitamin D as described previously (Smith et al. 2005a,b, 2008, 2009a, 2012b; Zwart et al. 2011b, 2013).

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We follow Gomes, Kogan, and Zhang (2003) and Gomes and Schmid (2012) in assuming that every period, there is a unit mass of potential entrant firms.

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Most early work assumed some limited amount of supervision (e.g., a small list of translation seeds) for this task, recent work has shown that unsupervised methods can perform on-par and often above early supervised methods [Artetxe et al., 2018a, Conneau et al., 2018].

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The overall sound level of control and other auditory stimuli was roved from 50 to 80 dB SPL in steps of 2 dB. Horizontal and vertical gaze positions were determined separately by a velocity criterion (Populin and Yin 1998; Tollin et al. 2005).

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However, this resistance to drought is much lower than observed for many Pulmonates which may survive several months or even more to the desiccation (Barbosa and Barbosa 1959; Cridland 1967; Véra et al. 1994).

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Initially, utterance-dependent generative models were obtained by MAP adapting an appropriate gender-dependent background model using the provided gender information.

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Although FGF23 and FGF2 can both induce hypertrophic growth of cardiac myocytes, FGF23 does so primarily by stimulating PLCg/calcineurin/NFAT signaling, whereas FGF2 activates the Ras/MAPK signaling axis (Faul et al., 2011).

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intermedia, mapped in previous studies (NLGANSIETDVSFDDNANPEYTYHGIP, SKKYENFN DFLKGLR and NCNKNDHLFACW) (19, 21).

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The affected follicular structure is unable to develop terminal hair and sebaceous glands, producing only soft keratin and, more rarely, vellus hair that occludes the adnexal ostia instead (4,7).

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The methods of animal training, stimulus delivery, and physiological recording have been described previously (Malone et al. 2002, 2007, 2010, 2014; Scott et al. 2007, 2009, 2011).

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First, this information is the basis for ecological models and predictions of the future invasive distribution of H. axyridis (Poutsma et al. 2008; Bidinger et al. 2012).

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The above estimator generalizes the estimator in Sriperumbudur et al., 2017 to conditional densities.

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[4] mathematically proved the reconstruction of analog signals, with an error as low as required, from the pulses under certain conditions; thus, APC is an alternative to conventional ADC and has sparse representations, at least for certain impulsive classes of signals [5]–[7].

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…2016), swine wastewater (Reddy et al., 2001; Lee et al., 2004; Kantawanichkul & Somprasert, 2005; Tunçsiper et al., 2015), plant nursery runoff (Huett et al., 2005), barnyardmanure (Hill et al., 2000), winery wastewater (De la Varga et al., 2013; Serrano et al., 2011; Rozema et al., 2016),…

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recently an elegant study in a mouse model lacking cone Pde6c showed that cones expressed the rod photoreceptor Pde6a/b subunit proteins and that these subunits were used instead for cone phototransduction.(32) Therefore, the expression of rod phototransduction genes in FACS Tg(TaCP:EGFP) wild-type and mutant cones was examined.

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The reasons for this disparity cannot be established from our data set, although in China, one barrier to effective provision of GOLD-recommended treatments has been identified as the self-administration of nonprescription medicines by individuals with COPD.(16) A particular focus of this study was translating the impact of increments in activity impairment on HCRU and work productivity.

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…for remediation of runoff from agricultural irrigation and agro-industrial production has become increasingly popular over the last decades, due to their low capital and operational cost, low energy consumption, and environmental friendliness (Huett et al., 2005; Scholz, 2007; Carty et al., 2008).

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Reads per kilobase per million (RPKM (Mortazavi et al. 2008)) were computed at all sites for each individual using a custom Perl script to parse the mapping files.

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We conducted semi-structured interviews during September 2005-March 2006, seeking to identify (1) VA and non-VA data sources being used or developed, (2) any information system being utilized or developed, (3) any role in governance of data or information systems, (4) expected changes in data sources or information systems as a result of implementation research efforts, (5) identify perceived barriers regarding HIT, and (6) solicit a prioritized list of HIT needs to support the QUERI Center’s implementation research efforts.

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Given INF2’s previously established role as a formin protein involved in ER-mediated mitochondrial constriction and division (Korobova et al., 2013, 2014; Hatch et al., 2014), we hypothesized that Spire1C could be working together with INF2.

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Our result is consistent with the anticancer activity of EGCG found in other human cancers, such as gastric [15], colorectal [16], lung [17], breast [18], ovarian [19], and prostate cancer [20].

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Previous work has shown that such measures are related to dual tasking measures of gait variability (Springer et al. 2006; Yogev et al. 2005) and that they respond as expected to cognitive-enhancing pharmacologic therapy (Auriel et al. 2006).

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To satisfy properties 1–4 above and to handle the mixed data types, we use approximations to the error functions developed for support vector machines (SVM) [36, 38, 39].

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Taking into consideration the results of the present study and previous reports, it seems possible that LPZ stimulates the transfer of NF-kB into the nucleus during LPS-stimulated TLR4 signal transduction, which, in turn, leads to the induc- Effects of Lansoprazole on the TLR4 Signal Transduction Vol. 45, No. 2, 2009 245 tion of SOCS1 expression and anti-inflammatory activity.

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Meta-analyses have shown wound problems, infection, or paresthesia to be signiWcant complications associated with surgical treatment [14, 31], even though percutaneous techniques seem to reduce the rate of complications [7].

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Structures used in the work Four structures (Berman et al. 2000) were used in this work, representing the three functional states of calmodulin.

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The so-called treated samples reported in this investigation were obtained on a single day during a patient/parent meeting, following dietary prescriptions for the days preceding sampling (Dercksen et al. 2012).

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In the P-element mediated transformation systems, transposons that contain proper cis elements are able to amplify at ectopic genomic loci, although levels of amplification are dramatically affected by chromosomal position effects (de Cicco and Spradling, 1984; Orr-Weaver and Spradling, 1986).

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Several studies have shown that a major function of PP2A is downregulation of the Ras/MAP kinase pathway (2, 3, 22, 30, 50, 51, 53).

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Particularly, the visceral tissue volume at 41–50% LTR, which has high conductivity because it is mainly made up of smooth muscle and water, has a low but significant negative correlation between the residual of the trunk SM volume estimates, expressed as a percentage of the trunk SM volume (13).

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 The GRS was then calculated by summing across all SNPs (the GRS could theoretically range from 0 to 58).

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This includes methods for computing mappings between probability densities [23, 39, 40], often using formal and computational tools from optimal transport theory and measure coupling.

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The multi-institution RCTs [11, 13, 44, 56, 65] and the pilot RCT by Tsai et al.

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Additionally, the results surpassed the numbers of 8–9 h of “lying down” reported in two studies on persons with moderate or severe OSAS [21, 22] and the 9 h and 55 min of sedentary time previously reported in patients with OSAS and obesity receiving CPAP treatment [23].

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The scaffold protein Kidins220(1)/ ARMS (1,2), hereafter referred to as Kidins220, acts as a signaling platform implicated in many cellular

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In this regard, expression of VvMYB4-like and the gentian GtMYB1R1 and GtMYB1R9 share the down-regulation of the endogenous DFR and ANS (Nakatsuka et al. 2013), whereas with the overexpression of the strawberry FaMYB1, it is shared only the down-regulation of ANS/ LDOX (Aharoni et al. 2001).

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It may be interesting to study the security in context of multi-level proxy signatures [16].

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We note that better performance has been reported with the use of more image features [6].

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This finding was in complete agreement with previous reports in which E2 was found to be more antigenic than E1 in infected patients (Edwards et al., 2012; Neumann-Haefelin & Thimme, 2013; Prince et al., 1999; Shimizu et al., 1994; Wahid & Dubuisson, 2013; Wang et al., 2011).

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In [37], DWT coefficients in each color components are modeled jointly by Multivariate Generalized Gaussian (MGG), and geodesic distance is used as the similarity measure.

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Ovigerous females (Tankersley et al. 1998; Forward et al. 2003) and females between clutches of eggs (Hench et al. 2004; Forward et al. 2005) use ETT to migrate seaward.

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Furthermore, MMP-2 and -9 are expressed and secreted by astrocytes (Gottschall et al., 1995; Muir et al., 2002) and induced in the presence of A (Deb and Gottschall, 1996; Deb et al.

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Therefore, physiologically relevant 3D cell culture has been recognized as a potential bridge between traditional in vitro two-dimensional (2D) culture and in vivo animal studies.(7,8) It is thus critical to advance the development of scalable and affordable methods of producing 3D spheroids and/or organoids suitable for high-throughput cancer drug discovery.

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Only few published methods used tandem mass spectrometry as a detection method for simultaneous determination of oxycodone and its metabolites in human biological samples [18, 19].

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As discussed in [71, 72], such an ability leads to higher market efficiency, where both the cloud provider and cloud customers gain benefit.

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Whereas Lorden used crude upper bounds for the Type I error probability that are too conservative for practical applications, Bartroff and Lai (2008) overcome this difficulty by developing numerical methods to compute the Type I error probability and also extended the three-stage test to multiparameter and multi-armed settings, thus greatly broadening the scope of these efficient adaptive designs. A review of their method is given in Section 2.1. In Section 4 we prove the asymptotic optimality of these adaptive tests in the multiparameter case, extending Lorden’s (1983) result for the special case d = 1.

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7 Precision of our video-based fish species recognition results [2] on the FishCLEF 31K dataset Multimed Tools Appl (2016) 75:1701–1720 1712

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3, top) was constructed from the previously described 0.85-kb promoter construct (construct 6, Drews et al. 2005) by digestion with AscI and MluI followed by religation.

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Furthermore, it has been shown that expression of small t can enhance MEK and MAP kinase activity (51, 53).

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Additional target-based ESI–MS-MS data of isovalerylcarnitine was obtained from the preceding investigation (Dercksen et al. 2012) and the analysis was done according to the protocol described by Pitt et al.

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These descriptors are usually applied with the Harris3D corner detector [16],

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To minimise the gap between the two fragments in closed wedge osteotomy, impaction is required when using the plating technique [4, 10, 17, 19, 30].

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and has been implicated in Salmonella survival in the inflamed intestine when bile levels are elevated (18).

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…importance of polyploidy because (1) life history traits are often main determinants of fitness (e.g., Levy and Feldman 2002; Otto 2007; Ramsey 2011), and (2), ploidy level has the potential to influence life history traits in both positive and negative ways (e.g., Cavalier-Smith 1978;…

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The real-world spaces that surround information users have been diversely called everything from personal information environments (Kwasnik, 1991; Malone, 1983) to personal information management (PIM) systems (Barreau, 1995) and personal spaces of information (Jones, 2007). Drawing upon interviews with academics, Lee (2003) proposes a model of three concentric zones of information that surround a user: “immediate,” within arm’s reach or a few footsteps away; “adjacent,” such as a nearby university library; and “outside,” such as a more distant bookstore. Speaking largely from an objectifying stance and adopting Lee’s concept of the “immediate information space,” this paper focuses on a visual research method—photography— that seems particularly well suited to learning more about settings and their accompanying information phenomena. A variety of investigative approaches may be used to study immediate information space. Jones (2007) suggests ethnography combined with design methodologies, and places emphasis on context and situation, including contextual inquiry (Beyer & Holtzblatt, 1998), situated activity (Suchman, 1983), and situated design (Greenbaum & Kyng, 1991).

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It has to be emphasized that this paper focuses on the competition of digital platforms that operate as ubiquitous systems [57].

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Given that meningovascular involvement is the most prevalent form of neurosyphilis, the signal changes could represent a combination of edema and gliosis [2, 5].

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The previous studies confirm that feeding healthy rats a fructose diet results in insulin resistance, hyperinsulinemia, and hypertension (Johnson et al., 2007; Suzuki et al., 1997).

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Outlines of the subgranular zone (SGZ: defined as a two cell diameter band on both sides of the granular cell layer (GCL)) was done using a 10x/0.45 objective.

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The loss of ATP is caused by the impairment to ATP recycling, depletion of substrates, and inhibition of complex IV in the respiratory chain [21, 23, 33, 64, 100, 101, 107–116].

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The incidence of 12.5% Cronobacter contamination of PIF in Malaysia was almost in agreement with reports of Cawthorn et al. (2008) and Witthuhn et al. (2006) who found the prevalence of Cronobacter in South African PIF were 14 and 18%, respectively.

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Moreover, genu as well as splenium thinning may corroborate results from our previous work (Ballmaier et al, 2004c), showing widespread decreases in temporal and parietal gray matter in late-onset depression compared to controls, with prominent decreases in sensorimotor regions.

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The early studies also documented that the activity of daptomycin was dependent on the concentration of calcium in the growth medium (8, 11, 12, 14).

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We additionally analyzed blood levels of the hematopoietic cytokine granulocyte colony-stimulating factor (G-CSF) since it might be the mediator of increased CD34 /KDR and CD45 /CD34 cell mobilization (11, 26).

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Other studies showed that ACR could affect the cellular energy generation and the deficiency of energy induced the neurotoxicity [7, 8].

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eported intradural spinal metastasis with histological confirmed xamination since 1950 add to 82 and only rarely are reported to be rostate carcinoma [3–6].

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…associated with the tip and kinocilial links of sensory hair bundles in the chick inner ear and the ciliary calyx of photoreceptors in the eye (Goodyear and Richardson, 2003), is an avian ortholog of human protocadherin-15, a product of the deaf/ blindness Usher syndrome type 1F/DFNB23 locus…

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Whereas critics like Karnani (2007) have mostly raised questions regarding cosmetic skin whitening creams, our research examines whether the effects of disempowerment might be particularly prominent for the riskier creams.

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Local phase coherence (LPC) of the wavelet image coefficients is employed in [14] to evaluate the image sharpness.

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Although early studies linked cFos expression to neuronal activity (Sommer et al., 1993, 1996), only recently these neurons were directly implicated in internal representation and behavioral expression of distinct memories (Cruz et al., 2013, 2014a).