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dict |
|---|---|---|
{
"aliases": null,
"definition": "A primary amino compound that is the 5-hydroxy derivative of tryptamine.",
"id": "Serotonin",
"label": "serotonin",
"logical_definition": null,
"original_id": "CHEBI:28790",
"relationships": [
{
"predicate": "HasRole",
"target": "Neurotransmitter"
},
{
"predicate": "HasRole",
"target": "MouseMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Tryptamine"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "Serotonin1_"
},
{
"predicate": "subClassOf",
"target": "MonoamineMolecularMessenger"
},
{
"predicate": "subClassOf",
"target": "Tryptamines"
},
{
"predicate": "subClassOf",
"target": "Phenols"
},
{
"predicate": "subClassOf",
"target": "PrimaryAminoCompound"
},
{
"predicate": "subClassOf",
"target": "Hydroxyindoles"
}
]
}
| 0 |
{
"document": "serotonin A primary amino compound that is the 5-hydroxy derivative of tryptamine. [{'predicate': 'HasRole', 'target': 'Neurotransmitter'}, {'predicate': 'HasRole', 'target': 'MouseMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'Tryptamine'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': 'Serotonin1_'}, {'predicate': 'subClassOf', 'target': 'MonoamineMolecularMessenger'}, {'predicate': 'subClassOf', 'target': 'Tryptamines'}, {'predicate': 'subClassOf', 'target': 'Phenols'}, {'predicate': 'subClassOf', 'target': 'PrimaryAminoCompound'}, {'predicate': 'subClassOf', 'target': 'Hydroxyindoles'}]"
}
|
{
"aliases": null,
"definition": "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3.",
"id": "Serotonin1_",
"label": "serotonin(1+)",
"logical_definition": null,
"original_id": "CHEBI:350546",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "Serotonin"
},
{
"predicate": "subClassOf",
"target": "AmmoniumIonDerivative"
}
]
}
| 0 |
{
"document": "serotonin(1+) An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': 'Serotonin'}, {'predicate': 'subClassOf', 'target': 'AmmoniumIonDerivative'}]"
}
|
{
"aliases": null,
"definition": "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",
"id": "SerotoninProductionInvolvedInInflammatoryResponse",
"label": "serotonin production involved in inflammatory response",
"logical_definition": null,
"original_id": "GO:0002351",
"relationships": [
{
"predicate": "subClassOf",
"target": "ProductionOfMolecularMediatorInvolvedInInflammatoryResponse"
}
]
}
| 0 |
{
"document": "serotonin production involved in inflammatory response The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. [{'predicate': 'subClassOf', 'target': 'ProductionOfMolecularMediatorInvolvedInInflammatoryResponse'}]"
}
|
{
"aliases": null,
"definition": "A cell type that secretes 5-Hydroxytryptamine (serotonin).",
"id": "SerotoninSecretingCell",
"label": "serotonin secreting cell",
"logical_definition": null,
"original_id": "CL:0000458",
"relationships": [
{
"predicate": "subClassOf",
"target": "BiogenicAmineSecretingCell"
}
]
}
| 0 |
{
"document": "serotonin secreting cell A cell type that secretes 5-Hydroxytryptamine (serotonin). [{'predicate': 'subClassOf', 'target': 'BiogenicAmineSecretingCell'}]"
}
|
{
"aliases": null,
"definition": "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.",
"id": "SerotoninSecretion",
"label": "serotonin secretion",
"logical_definition": null,
"original_id": "GO:0001820",
"relationships": [
{
"predicate": "subClassOf",
"target": "SerotoninTransport"
},
{
"predicate": "subClassOf",
"target": "SignalRelease"
}
]
}
| 0 |
{
"document": "serotonin secretion The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. [{'predicate': 'subClassOf', 'target': 'SerotoninTransport'}, {'predicate': 'subClassOf', 'target': 'SignalRelease'}]"
}
|
{
"aliases": null,
"definition": "The regulated release of serotonin by a cell as part of an inflammatory response.",
"id": "SerotoninSecretionInvolvedInInflammatoryResponse",
"label": "serotonin secretion involved in inflammatory response",
"logical_definition": null,
"original_id": "GO:0002442",
"relationships": [
{
"predicate": "PartOf",
"target": "SerotoninProductionInvolvedInInflammatoryResponse"
},
{
"predicate": "subClassOf",
"target": "SerotoninSecretion"
}
]
}
| 0 |
{
"document": "serotonin secretion involved in inflammatory response The regulated release of serotonin by a cell as part of an inflammatory response. [{'predicate': 'PartOf', 'target': 'SerotoninProductionInvolvedInInflammatoryResponse'}, {'predicate': 'subClassOf', 'target': 'SerotoninSecretion'}]"
}
|
{
"aliases": null,
"definition": "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.",
"id": "SerotoninTransport",
"label": "serotonin transport",
"logical_definition": null,
"original_id": "GO:0006837",
"relationships": [
{
"predicate": "subClassOf",
"target": "MonoamineTransport"
},
{
"predicate": "subClassOf",
"target": "OrganicHydroxyCompoundTransport"
}
]
}
| 0 |
{
"document": "serotonin transport The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. [{'predicate': 'subClassOf', 'target': 'MonoamineTransport'}, {'predicate': 'subClassOf', 'target': 'OrganicHydroxyCompoundTransport'}]"
}
|
{
"aliases": null,
"definition": "The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells.",
"id": "SerousAcinus",
"label": "serous acinus",
"logical_definition": null,
"original_id": "UBERON:0013232",
"relationships": [
{
"predicate": "ComposedPrimarilyOf",
"target": "SerousSecretingCell"
}
]
}
| 0 |
{
"document": "serous acinus The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells. [{'predicate': 'ComposedPrimarilyOf', 'target': 'SerousSecretingCell'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SerousCavity",
"label": "serous cavity",
"logical_definition": null,
"original_id": "UBERON:0035809",
"relationships": null
}
| 0 |
{
"document": "serous cavity None None"
}
|
{
"aliases": null,
"definition": "A serous secreting cell that is part of the epithelium of bronchus.",
"id": "SerousCellOfEpitheliumOfBronchus",
"label": "serous cell of epithelium of bronchus",
"logical_definition": null,
"original_id": "CL:1000331",
"relationships": [
{
"predicate": "subClassOf",
"target": "AnimalCell"
}
]
}
| 0 |
{
"document": "serous cell of epithelium of bronchus A serous secreting cell that is part of the epithelium of bronchus. [{'predicate': 'subClassOf', 'target': 'AnimalCell'}]"
}
|
{
"aliases": null,
"definition": "A serous secreting cell that is part of the epithelium of terminal bronchiole.",
"id": "SerousCellOfEpitheliumOfTerminalBronchiole",
"label": "serous cell of epithelium of terminal bronchiole",
"logical_definition": null,
"original_id": "CL:1000332",
"relationships": [
{
"predicate": "subClassOf",
"target": "AnimalCell"
}
]
}
| 0 |
{
"document": "serous cell of epithelium of terminal bronchiole A serous secreting cell that is part of the epithelium of terminal bronchiole. [{'predicate': 'subClassOf', 'target': 'AnimalCell'}]"
}
|
{
"aliases": null,
"definition": "A serous secreting cell that is part of the epithelium of trachea.",
"id": "SerousCellOfEpitheliumOfTrachea",
"label": "serous cell of epithelium of trachea",
"logical_definition": null,
"original_id": "CL:1000330",
"relationships": [
{
"predicate": "subClassOf",
"target": "SerousSecretingCell"
},
{
"predicate": "subClassOf",
"target": "AnimalCell"
}
]
}
| 0 |
{
"document": "serous cell of epithelium of trachea A serous secreting cell that is part of the epithelium of trachea. [{'predicate': 'subClassOf', 'target': 'SerousSecretingCell'}, {'predicate': 'subClassOf', 'target': 'AnimalCell'}]"
}
|
{
"aliases": null,
"definition": "A gland in which the principal secretory cells are serous secreting cells.",
"id": "SerousGland",
"label": "serous gland",
"logical_definition": null,
"original_id": "UBERON:0000409",
"relationships": [
{
"predicate": "HasPart",
"target": "SerousAcinus"
},
{
"predicate": "Produces",
"target": "SecretionOfSerousGland"
}
]
}
| 0 |
{
"document": "serous gland A gland in which the principal secretory cells are serous secreting cells. [{'predicate': 'HasPart', 'target': 'SerousAcinus'}, {'predicate': 'Produces', 'target': 'SecretionOfSerousGland'}]"
}
|
{
"aliases": null,
"definition": "Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer.",
"id": "SerousMembrane",
"label": "serous membrane",
"logical_definition": null,
"original_id": "UBERON:0000042",
"relationships": [
{
"predicate": "PartOf",
"target": "AnatomicalWall"
},
{
"predicate": "HasPart",
"target": "Mesothelium"
},
{
"predicate": "HasPart",
"target": "ConnectiveTissue"
},
{
"predicate": "DevelopsFrom",
"target": "Mesoderm"
},
{
"predicate": "subClassOf",
"target": "MultiTissueStructure"
}
]
}
| 0 |
{
"document": "serous membrane Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer. [{'predicate': 'PartOf', 'target': 'AnatomicalWall'}, {'predicate': 'HasPart', 'target': 'Mesothelium'}, {'predicate': 'HasPart', 'target': 'ConnectiveTissue'}, {'predicate': 'DevelopsFrom', 'target': 'Mesoderm'}, {'predicate': 'subClassOf', 'target': 'MultiTissueStructure'}]"
}
|
{
"aliases": null,
"definition": "Accumulation of serous fluid (pale yellow and transparent fluid) in the pericardial sac.",
"id": "SerousPericardialEffusion",
"label": "Serous pericardial effusion",
"logical_definition": null,
"original_id": "HP:0011853",
"relationships": [
{
"predicate": "subClassOf",
"target": "PericardialEffusion"
}
]
}
| 0 |
{
"document": "Serous pericardial effusion Accumulation of serous fluid (pale yellow and transparent fluid) in the pericardial sac. [{'predicate': 'subClassOf', 'target': 'PericardialEffusion'}]"
}
|
{
"aliases": null,
"definition": "Serous membrane which is divided into parietal and visceral serous pericardium.",
"id": "SerousPericardium",
"label": "serous pericardium",
"logical_definition": null,
"original_id": "UBERON:0002357",
"relationships": [
{
"predicate": "PartOf",
"target": "PericardialSac"
},
{
"predicate": "HasPart",
"target": "ParietalSerousPericardium"
},
{
"predicate": "HasPart",
"target": "VisceralSerousPericardium"
},
{
"predicate": "AttachedTo",
"target": "FibrousPericardium"
},
{
"predicate": "subClassOf",
"target": "SerousMembrane"
}
]
}
| 0 |
{
"document": "serous pericardium Serous membrane which is divided into parietal and visceral serous pericardium. [{'predicate': 'PartOf', 'target': 'PericardialSac'}, {'predicate': 'HasPart', 'target': 'ParietalSerousPericardium'}, {'predicate': 'HasPart', 'target': 'VisceralSerousPericardium'}, {'predicate': 'AttachedTo', 'target': 'FibrousPericardium'}, {'predicate': 'subClassOf', 'target': 'SerousMembrane'}]"
}
|
{
"aliases": null,
"definition": "Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA].",
"id": "SerousSac",
"label": "serous sac",
"logical_definition": null,
"original_id": "UBERON:0005906",
"relationships": [
{
"predicate": "HasPart",
"target": "SerousMembrane"
},
{
"predicate": "HasPart",
"target": "AnatomicalCavity"
},
{
"predicate": "subClassOf",
"target": "Organ"
}
]
}
| 0 |
{
"document": "serous sac Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA]. [{'predicate': 'HasPart', 'target': 'SerousMembrane'}, {'predicate': 'HasPart', 'target': 'AnatomicalCavity'}, {'predicate': 'subClassOf', 'target': 'Organ'}]"
}
|
{
"aliases": null,
"definition": "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid.",
"id": "SerousSecretingCell",
"label": "serous secreting cell",
"logical_definition": null,
"original_id": "CL:0000313",
"relationships": [
{
"predicate": "subClassOf",
"target": "SeromucusSecretingCell"
}
]
}
| 0 |
{
"document": "serous secreting cell Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid. [{'predicate': 'subClassOf', 'target': 'SeromucusSecretingCell'}]"
}
|
{
"aliases": null,
"definition": "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland.",
"id": "SerousSecretingCellOfBronchusSubmucosalGland",
"label": "serous secreting cell of bronchus submucosal gland",
"logical_definition": null,
"original_id": "CL:4033005",
"relationships": null
}
| 0 |
{
"document": "serous secreting cell of bronchus submucosal gland A(n) serous secreting cell that is part of a(n) bronchus submucosal gland. None"
}
|
{
"aliases": null,
"definition": "Elongated curved (S-shaped) fibulae.",
"id": "SerpentineFibula",
"label": "Serpentine fibula",
"logical_definition": null,
"original_id": "HP:0030045",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfFibulaMorphology"
}
]
}
| 0 |
{
"document": "Serpentine fibula Elongated curved (S-shaped) fibulae. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfFibulaMorphology'}]"
}
|
{
"aliases": null,
"definition": "Curving course of the crus of the helix, approaching or joining the antitragus.",
"id": "SerpiginousCrusOfHelix",
"label": "Serpiginous crus of helix",
"logical_definition": null,
"original_id": "HP:0011257",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfTheCrusOfTheHelix"
}
]
}
| 0 |
{
"document": "Serpiginous crus of helix Curving course of the crus of the helix, approaching or joining the antitragus. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTheCrusOfTheHelix'}]"
}
|
{
"aliases": null,
"definition": "A skin lesion with a snake- or serpent-like distribution.",
"id": "SerpiginousCutaneousLesion",
"label": "Serpiginous cutaneous lesion",
"logical_definition": null,
"original_id": "HP:0025527",
"relationships": [
{
"predicate": "subClassOf",
"target": "LocalizedSkinLesion"
}
]
}
| 0 |
{
"document": "Serpiginous cutaneous lesion A skin lesion with a snake- or serpent-like distribution. [{'predicate': 'subClassOf', 'target': 'LocalizedSkinLesion'}]"
}
|
{
"aliases": null,
"definition": "Posterior curving of the antihelix from its origin at the antitragus, traveling initially almost perpendicular to the descending helix and obscuring some of the concha.",
"id": "SerpiginousStemOfAntihelix",
"label": "Serpiginous stem of antihelix",
"logical_definition": null,
"original_id": "HP:0011241",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalityOfStemOfAntihelix"
}
]
}
| 0 |
{
"document": "Serpiginous stem of antihelix Posterior curving of the antihelix from its origin at the antitragus, traveling initially almost perpendicular to the descending helix and obscuring some of the concha. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfStemOfAntihelix'}]"
}
|
{
"aliases": null,
"definition": "Incisor teeth with irregular edges said to resemble a saw.",
"id": "SerratedIncisors",
"label": "Serrated incisors",
"logical_definition": null,
"original_id": "HP:0034270",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalIncisorMorphology"
}
]
}
| 0 |
{
"document": "Serrated incisors Incisor teeth with irregular edges said to resemble a saw. [{'predicate': 'subClassOf', 'target': 'AbnormalIncisorMorphology'}]"
}
|
{
"aliases": null,
"definition": "The presence of multiple serrated polyps in the intestine. Unlike conventional adenomas, which are uniformly dysplastic, the vast majority of serrated lesions contain no dysplasia. The serrated class includes the hyperplastic polyps, which are not considered precancerous; sessile serrated polyps (also called sessile serrated adenomas); and traditional serrated adenomas. Sessile serrated polyps are larger on average and more often located in the proximal colon. Sessile serrated polyps have a more irregular surface, a pattern to the surface that has been called cloudlike, and indistinct edges compared with hyperplastic polyps. Sessile serrated polyps also have large open pits on the surface (type O pits) when viewed with magnification.",
"id": "SerratedIntestinalPolyps",
"label": "Serrated intestinal polyps",
"logical_definition": null,
"original_id": "HP:0032222",
"relationships": [
{
"predicate": "subClassOf",
"target": "IntestinalPolyposis"
}
]
}
| 0 |
{
"document": "Serrated intestinal polyps The presence of multiple serrated polyps in the intestine. Unlike conventional adenomas, which are uniformly dysplastic, the vast majority of serrated lesions contain no dysplasia. The serrated class includes the hyperplastic polyps, which are not considered precancerous; sessile serrated polyps (also called sessile serrated adenomas); and traditional serrated adenomas. Sessile serrated polyps are larger on average and more often located in the proximal colon. Sessile serrated polyps have a more irregular surface, a pattern to the surface that has been called cloudlike, and indistinct edges compared with hyperplastic polyps. Sessile serrated polyps also have large open pits on the surface (type O pits) when viewed with magnification. [{'predicate': 'subClassOf', 'target': 'IntestinalPolyposis'}]"
}
|
{
"aliases": null,
"definition": "The serratus ventralis is a muscle that originates on the surface of the upper eight or nine ribs at the side of the chest and inserts along the entire anterior length of the medial border of the scapula. [WP,unvetted].",
"id": "SerratusVentralis",
"label": "serratus ventralis",
"logical_definition": null,
"original_id": "UBERON:0001125",
"relationships": [
{
"predicate": "InnervatedBy",
"target": "ThoracicNerve"
},
{
"predicate": "DevelopsFrom",
"target": "SerratusVentralisPreMuscleMass"
},
{
"predicate": "HasMuscleOrigin",
"target": "Rib"
},
{
"predicate": "HasMuscleInsertion",
"target": "Scapula"
},
{
"predicate": "HasMuscleAntagonist",
"target": "TrapeziusMuscle"
},
{
"predicate": "subClassOf",
"target": "MuscleOfShoulder"
}
]
}
| 0 |
{
"document": "serratus ventralis The serratus ventralis is a muscle that originates on the surface of the upper eight or nine ribs at the side of the chest and inserts along the entire anterior length of the medial border of the scapula. [WP,unvetted]. [{'predicate': 'InnervatedBy', 'target': 'ThoracicNerve'}, {'predicate': 'DevelopsFrom', 'target': 'SerratusVentralisPreMuscleMass'}, {'predicate': 'HasMuscleOrigin', 'target': 'Rib'}, {'predicate': 'HasMuscleInsertion', 'target': 'Scapula'}, {'predicate': 'HasMuscleAntagonist', 'target': 'TrapeziusMuscle'}, {'predicate': 'subClassOf', 'target': 'MuscleOfShoulder'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SerratusVentralisPreMuscleMass",
"label": "serratus ventralis pre-muscle mass",
"logical_definition": null,
"original_id": "UBERON:0010986",
"relationships": [
{
"predicate": "PartOf",
"target": "AxialMuscle"
},
{
"predicate": "DevelopsFrom",
"target": "TrunkAndCervicalMyotomeGroup"
},
{
"predicate": "subClassOf",
"target": "PreMuscleCondensation"
}
]
}
| 0 |
{
"document": "serratus ventralis pre-muscle mass None [{'predicate': 'PartOf', 'target': 'AxialMuscle'}, {'predicate': 'DevelopsFrom', 'target': 'TrunkAndCervicalMyotomeGroup'}, {'predicate': 'subClassOf', 'target': 'PreMuscleCondensation'}]"
}
|
{
"aliases": null,
"definition": "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier.",
"id": "SertoliCell",
"label": "Sertoli cell",
"logical_definition": null,
"original_id": "CL:0000216",
"relationships": [
{
"predicate": "subClassOf",
"target": "BarrierCell"
},
{
"predicate": "subClassOf",
"target": "AndrogenBindingProteinSecretingCell"
},
{
"predicate": "subClassOf",
"target": "SupportingCell"
},
{
"predicate": "subClassOf",
"target": "SeminiferousTubuleEpithelialCell"
}
]
}
| 0 |
{
"document": "Sertoli cell A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. [{'predicate': 'subClassOf', 'target': 'BarrierCell'}, {'predicate': 'subClassOf', 'target': 'AndrogenBindingProteinSecretingCell'}, {'predicate': 'subClassOf', 'target': 'SupportingCell'}, {'predicate': 'subClassOf', 'target': 'SeminiferousTubuleEpithelialCell'}]"
}
|
{
"aliases": null,
"definition": "Abnormal increase in the number of Sertoli cells in the testis.",
"id": "SertoliCellHyperplasia",
"label": "Sertoli cell hyperplasia",
"logical_definition": null,
"original_id": "HP:0034746",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalTestisMorphology"
}
]
}
| 0 |
{
"document": "Sertoli cell hyperplasia Abnormal increase in the number of Sertoli cells in the testis. [{'predicate': 'subClassOf', 'target': 'AbnormalTestisMorphology'}]"
}
|
{
"aliases": null,
"definition": "The presence of a neoplasm of the testis with origin in a Sertoli cell.",
"id": "SertoliCellNeoplasm",
"label": "Sertoli cell neoplasm",
"logical_definition": null,
"original_id": "HP:0100619",
"relationships": [
{
"predicate": "subClassOf",
"target": "TesticularNeoplasm"
}
]
}
| 0 |
{
"document": "Sertoli cell neoplasm The presence of a neoplasm of the testis with origin in a Sertoli cell. [{'predicate': 'subClassOf', 'target': 'TesticularNeoplasm'}]"
}
|
{
"aliases": null,
"definition": "A histological phenotype observed on testicular biopsy in which only Sertoli cells line the seminiferous tubules of the testis.",
"id": "SertoliCellOnlyPhenotype",
"label": "Sertoli cell-only phenotype",
"logical_definition": null,
"original_id": "HP:0034299",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalTestisMorphology"
}
]
}
| 0 |
{
"document": "Sertoli cell-only phenotype A histological phenotype observed on testicular biopsy in which only Sertoli cells line the seminiferous tubules of the testis. [{'predicate': 'subClassOf', 'target': 'AbnormalTestisMorphology'}]"
}
|
{
"aliases": null,
"definition": "A sesamoid element that is composed of bone tissue.",
"id": "SesamoidBone",
"label": "sesamoid bone",
"logical_definition": null,
"original_id": "UBERON:0001479",
"relationships": [
{
"predicate": "subClassOf",
"target": "ShortBone"
}
]
}
| 0 |
{
"document": "sesamoid bone A sesamoid element that is composed of bone tissue. [{'predicate': 'subClassOf', 'target': 'ShortBone'}]"
}
|
{
"aliases": null,
"definition": "A sesamoid bone that is part of a manus.",
"id": "SesamoidBoneOfManus",
"label": "sesamoid bone of manus",
"logical_definition": null,
"original_id": "UBERON:0007997",
"relationships": [
{
"predicate": "PartOf",
"target": "SkeletonOfManus"
},
{
"predicate": "subClassOf",
"target": "SesamoidBone"
}
]
}
| 0 |
{
"document": "sesamoid bone of manus A sesamoid bone that is part of a manus. [{'predicate': 'PartOf', 'target': 'SkeletonOfManus'}, {'predicate': 'subClassOf', 'target': 'SesamoidBone'}]"
}
|
{
"aliases": null,
"definition": "A sesamoid bone that is part of a pes.",
"id": "SesamoidBoneOfPes",
"label": "sesamoid bone of pes",
"logical_definition": null,
"original_id": "UBERON:0008000",
"relationships": [
{
"predicate": "PartOf",
"target": "SkeletonOfPes"
},
{
"predicate": "subClassOf",
"target": "SesamoidBone"
}
]
}
| 0 |
{
"document": "sesamoid bone of pes A sesamoid bone that is part of a pes. [{'predicate': 'PartOf', 'target': 'SkeletonOfPes'}, {'predicate': 'subClassOf', 'target': 'SesamoidBone'}]"
}
|
{
"aliases": null,
"definition": "A sesamoid element that is composed primarily of cartilage tissue.",
"id": "SesamoidCartilage",
"label": "sesamoid cartilage",
"logical_definition": null,
"original_id": "UBERON:0013632",
"relationships": null
}
| 0 |
{
"document": "sesamoid cartilage A sesamoid element that is composed primarily of cartilage tissue. None"
}
|
{
"aliases": null,
"definition": "Ossicle that develops within bands of dense, regular connective tissue (e.g., tendons and ligaments). Sesamoids are generally located proximate to a bony prominence, over which the dense regular connective tissue wraps, and/or a joint or articulation.",
"id": "SesamoidElement",
"label": "sesamoid element",
"logical_definition": null,
"original_id": "UBERON:0013631",
"relationships": [
{
"predicate": "DevelopsIn",
"target": "DenseRegularConnectiveTissue"
},
{
"predicate": "subClassOf",
"target": "Ossicle"
}
]
}
| 0 |
{
"document": "sesamoid element Ossicle that develops within bands of dense, regular connective tissue (e.g., tendons and ligaments). Sesamoids are generally located proximate to a bony prominence, over which the dense regular connective tissue wraps, and/or a joint or articulation. [{'predicate': 'DevelopsIn', 'target': 'DenseRegularConnectiveTissue'}, {'predicate': 'subClassOf', 'target': 'Ossicle'}]"
}
|
{
"aliases": null,
"definition": "A tooth row that is part of a skeleton of lower jaw.",
"id": "SetOfLowerJawTeeth",
"label": "set of lower jaw teeth",
"logical_definition": null,
"original_id": "UBERON:0009679",
"relationships": null
}
| 0 |
{
"document": "set of lower jaw teeth A tooth row that is part of a skeleton of lower jaw. None"
}
|
{
"aliases": null,
"definition": null,
"id": "SetOfMusclesOfVertebralColumn",
"label": "set of muscles of vertebral column",
"logical_definition": null,
"original_id": "UBERON:0004468",
"relationships": null
}
| 0 |
{
"document": "set of muscles of vertebral column None None"
}
|
{
"aliases": null,
"definition": "A tooth row that is part of a skeleton of upper jaw.",
"id": "SetOfUpperJawTeeth",
"label": "set of upper jaw teeth",
"logical_definition": null,
"original_id": "UBERON:0009680",
"relationships": null
}
| 0 |
{
"document": "set of upper jaw teeth A tooth row that is part of a skeleton of upper jaw. None"
}
|
{
"aliases": null,
"definition": "An ophthalmologic sign in young children resulting from upward-gaze paresis. In this condition, the eyes appear driven downward, the sclera may be seen between the upper eyelid and the iris, and part of the lower pupil may be covered by the lower eyelid.",
"id": "SettingSunEyePhenomenon",
"label": "Setting-sun eye phenomenon",
"logical_definition": null,
"original_id": "HP:0012470",
"relationships": [
{
"predicate": "subClassOf",
"target": "Ophthalmoparesis"
}
]
}
| 0 |
{
"document": "Setting-sun eye phenomenon An ophthalmologic sign in young children resulting from upward-gaze paresis. In this condition, the eyes appear driven downward, the sclera may be seen between the upper eyelid and the iris, and part of the lower pupil may be covered by the lower eyelid. [{'predicate': 'subClassOf', 'target': 'Ophthalmoparesis'}]"
}
|
{
"aliases": null,
"definition": "Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean.",
"id": "Severe",
"label": "Severe",
"logical_definition": null,
"original_id": "HP:0012828",
"relationships": [
{
"predicate": "subClassOf",
"target": "Severity"
}
]
}
| 0 |
{
"document": "Severe Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [{'predicate': 'subClassOf', 'target': 'Severity'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe adenovirus infection.",
"id": "SevereAdenovirusInfection",
"label": "Severe adenovirus infection",
"logical_definition": null,
"original_id": "HP:0031694",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereViralInfection"
}
]
}
| 0 |
{
"document": "Severe adenovirus infection An unusually severe adenovirus infection. [{'predicate': 'subClassOf', 'target': 'SevereViralInfection'}]"
}
|
{
"aliases": null,
"definition": "The presence of severely increased concentrations of albumin in the urine, defined as an albumin-creatinine ratio greater than 300 mg/gm (greater than 34 mg/mmol).",
"id": "SevereAlbuminuria",
"label": "Severe albuminuria",
"logical_definition": null,
"original_id": "HP:0033066",
"relationships": [
{
"predicate": "subClassOf",
"target": "Albuminuria"
}
]
}
| 0 |
{
"document": "Severe albuminuria The presence of severely increased concentrations of albumin in the urine, defined as an albumin-creatinine ratio greater than 300 mg/gm (greater than 34 mg/mmol). [{'predicate': 'subClassOf', 'target': 'Albuminuria'}]"
}
|
{
"aliases": null,
"definition": "A severe form of B lymphocytopenia in which the count of B cells is very low or absent.",
"id": "SevereBLymphocytopenia",
"label": "Severe B lymphocytopenia",
"logical_definition": null,
"original_id": "HP:0005365",
"relationships": [
{
"predicate": "subClassOf",
"target": "BLymphocytopenia"
}
]
}
| 0 |
{
"document": "Severe B lymphocytopenia A severe form of B lymphocytopenia in which the count of B cells is very low or absent. [{'predicate': 'subClassOf', 'target': 'BLymphocytopenia'}]"
}
|
{
"aliases": null,
"definition": "A type of primary immune deficiency that is characterized by a more severe defect in both the T- and B-lymphocyte systems.",
"id": "SevereCombinedImmunodeficiency",
"label": "Severe combined immunodeficiency",
"logical_definition": null,
"original_id": "HP:0004430",
"relationships": [
{
"predicate": "subClassOf",
"target": "CombinedImmunodeficiency"
}
]
}
| 0 |
{
"document": "Severe combined immunodeficiency A type of primary immune deficiency that is characterized by a more severe defect in both the T- and B-lymphocyte systems. [{'predicate': 'subClassOf', 'target': 'CombinedImmunodeficiency'}]"
}
|
{
"aliases": null,
"definition": "A severe form of conductive hearing impairment.",
"id": "SevereConductiveHearingImpairment",
"label": "Severe conductive hearing impairment",
"logical_definition": null,
"original_id": "HP:0012717",
"relationships": [
{
"predicate": "subClassOf",
"target": "ConductiveHearingImpairment"
},
{
"predicate": "subClassOf",
"target": "MildHearingImpairment"
},
{
"predicate": "subClassOf",
"target": "SevereHearingImpairment"
}
]
}
| 0 |
{
"document": "Severe conductive hearing impairment A severe form of conductive hearing impairment. [{'predicate': 'subClassOf', 'target': 'ConductiveHearingImpairment'}, {'predicate': 'subClassOf', 'target': 'MildHearingImpairment'}, {'predicate': 'subClassOf', 'target': 'SevereHearingImpairment'}]"
}
|
{
"aliases": null,
"definition": "Peripheral visual field constriction with 10-19 degrees central field preserved.",
"id": "SevereConstrictionOfPeripheralVisualField",
"label": "Severe constriction of peripheral visual field",
"logical_definition": null,
"original_id": "HP:0030526",
"relationships": [
{
"predicate": "subClassOf",
"target": "ConstrictionOfPeripheralVisualField"
}
]
}
| 0 |
{
"document": "Severe constriction of peripheral visual field Peripheral visual field constriction with 10-19 degrees central field preserved. [{'predicate': 'subClassOf', 'target': 'ConstrictionOfPeripheralVisualField'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe infection by cytomegalovirus.",
"id": "SevereCytomegalovirusInfection",
"label": "Severe cytomegalovirus infection",
"logical_definition": null,
"original_id": "HP:0031692",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereViralInfection"
}
]
}
| 0 |
{
"document": "Severe cytomegalovirus infection An unusually severe infection by cytomegalovirus. [{'predicate': 'subClassOf', 'target': 'SevereViralInfection'}]"
}
|
{
"aliases": null,
"definition": "A severe loss of myelin from nerve fibers in the central nervous system.",
"id": "SevereDemyelinationOfTheWhiteMatter",
"label": "Severe demyelination of the white matter",
"logical_definition": null,
"original_id": "HP:0007258",
"relationships": [
{
"predicate": "subClassOf",
"target": "CNSDemyelination"
}
]
}
| 0 |
{
"document": "Severe demyelination of the white matter A severe loss of myelin from nerve fibers in the central nervous system. [{'predicate': 'subClassOf', 'target': 'CNSDemyelination'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe Epstein Barr virus (EBV) infection.",
"id": "SevereEpsteinBarrVirusInfection",
"label": "Severe Epstein Barr virus infection",
"logical_definition": null,
"original_id": "HP:0031693",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereViralInfection"
}
]
}
| 0 |
{
"document": "Severe Epstein Barr virus infection An unusually severe Epstein Barr virus (EBV) infection. [{'predicate': 'subClassOf', 'target': 'SevereViralInfection'}]"
}
|
{
"aliases": null,
"definition": "A severe delay in the acquisition of the ability to use language to communicate needs, wishes, or thoughts.",
"id": "SevereExpressiveLanguageDelay",
"label": "Severe expressive language delay",
"logical_definition": null,
"original_id": "HP:0006863",
"relationships": [
{
"predicate": "subClassOf",
"target": "ExpressiveLanguageDelay"
}
]
}
| 0 |
{
"document": "Severe expressive language delay A severe delay in the acquisition of the ability to use language to communicate needs, wishes, or thoughts. [{'predicate': 'subClassOf', 'target': 'ExpressiveLanguageDelay'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SevereFailureToThrive",
"label": "Severe failure to thrive",
"logical_definition": null,
"original_id": "HP:0001525",
"relationships": [
{
"predicate": "subClassOf",
"target": "FailureToThrive"
}
]
}
| 0 |
{
"document": "Severe failure to thrive None [{'predicate': 'subClassOf', 'target': 'FailureToThrive'}]"
}
|
{
"aliases": null,
"definition": "Severe degree of osteoporosis.",
"id": "SevereGeneralizedOsteoporosis",
"label": "Severe generalized osteoporosis",
"logical_definition": null,
"original_id": "HP:0005897",
"relationships": [
{
"predicate": "subClassOf",
"target": "GeneralizedOsteoporosis"
}
]
}
| 0 |
{
"document": "Severe generalized osteoporosis Severe degree of osteoporosis. [{'predicate': 'subClassOf', 'target': 'GeneralizedOsteoporosis'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe infection due to Giardia lamblia, also called Giardia duodenalis or Giardia intestinalis, which is a protozoan parasite of the small intestine that causes extensive morbidity worldwide.",
"id": "SevereGiardiasis",
"label": "Severe giardiasis",
"logical_definition": null,
"original_id": "HP:0020106",
"relationships": [
{
"predicate": "subClassOf",
"target": "UnusualProtozoanInfection"
}
]
}
| 0 |
{
"document": "Severe giardiasis An unusually severe infection due to Giardia lamblia, also called Giardia duodenalis or Giardia intestinalis, which is a protozoan parasite of the small intestine that causes extensive morbidity worldwide. [{'predicate': 'subClassOf', 'target': 'UnusualProtozoanInfection'}]"
}
|
{
"aliases": null,
"definition": "A severe delay in the achievement of motor or mental milestones in the domains of development of a child.",
"id": "SevereGlobalDevelopmentalDelay",
"label": "Severe global developmental delay",
"logical_definition": null,
"original_id": "HP:0011344",
"relationships": [
{
"predicate": "subClassOf",
"target": "GlobalDevelopmentalDelay"
}
]
}
| 0 |
{
"document": "Severe global developmental delay A severe delay in the achievement of motor or mental milestones in the domains of development of a child. [{'predicate': 'subClassOf', 'target': 'GlobalDevelopmentalDelay'}]"
}
|
{
"aliases": null,
"definition": "A severe form of hearing impairment.",
"id": "SevereHearingImpairment",
"label": "Severe hearing impairment",
"logical_definition": null,
"original_id": "HP:0012714",
"relationships": [
{
"predicate": "subClassOf",
"target": "HearingImpairment"
}
]
}
| 0 |
{
"document": "Severe hearing impairment A severe form of hearing impairment. [{'predicate': 'subClassOf', 'target': 'HearingImpairment'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SevereHydrocephalus",
"label": "Severe hydrocephalus",
"logical_definition": null,
"original_id": "HP:0006882",
"relationships": [
{
"predicate": "subClassOf",
"target": "Hydrocephalus"
}
]
}
| 0 |
{
"document": "Severe hydrocephalus None [{'predicate': 'subClassOf', 'target': 'Hydrocephalus'}]"
}
|
{
"aliases": null,
"definition": "A type of infection that is regarded as a sign of a pathological susceptibility to infection because of unusual severity or intensity of the infection.",
"id": "SevereInfection",
"label": "Severe infection",
"logical_definition": null,
"original_id": "HP:0032169",
"relationships": [
{
"predicate": "subClassOf",
"target": "UnusualInfection"
}
]
}
| 0 |
{
"document": "Severe infection A type of infection that is regarded as a sign of a pathological susceptibility to infection because of unusual severity or intensity of the infection. [{'predicate': 'subClassOf', 'target': 'UnusualInfection'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe infection by an influenza virus.",
"id": "SevereInfluenzaInfection",
"label": "Severe influenza infection",
"logical_definition": null,
"original_id": "HP:0034249",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereViralInfection"
}
]
}
| 0 |
{
"document": "Severe influenza infection An unusually severe infection by an influenza virus. [{'predicate': 'subClassOf', 'target': 'SevereViralInfection'}]"
}
|
{
"aliases": null,
"definition": "An intensity which is extremely bad or unpleasant in type or degree or effect or force.",
"id": "SevereIntensity",
"label": "severe intensity",
"logical_definition": null,
"original_id": "PATO:0000396",
"relationships": [
{
"predicate": "subClassOf",
"target": "Intensity"
}
]
}
| 0 |
{
"document": "severe intensity An intensity which is extremely bad or unpleasant in type or degree or effect or force. [{'predicate': 'subClassOf', 'target': 'Intensity'}]"
}
|
{
"aliases": null,
"definition": "Intrauterine growth retardation that is 4 or more standard deviations below average, corrected for sex and gestational age.",
"id": "SevereIntrauterineGrowthRetardation",
"label": "Severe intrauterine growth retardation",
"logical_definition": null,
"original_id": "HP:0008846",
"relationships": [
{
"predicate": "subClassOf",
"target": "IntrauterineGrowthRetardation"
}
]
}
| 0 |
{
"document": "Severe intrauterine growth retardation Intrauterine growth retardation that is 4 or more standard deviations below average, corrected for sex and gestational age. [{'predicate': 'subClassOf', 'target': 'IntrauterineGrowthRetardation'}]"
}
|
{
"aliases": null,
"definition": "A severe form of lactic acidemia.",
"id": "SevereLacticAcidosis",
"label": "Severe lactic acidosis",
"logical_definition": null,
"original_id": "HP:0004900",
"relationships": [
{
"predicate": "subClassOf",
"target": "LacticAcidosis"
}
]
}
| 0 |
{
"document": "Severe lactic acidosis A severe form of lactic acidemia. [{'predicate': 'subClassOf', 'target': 'LacticAcidosis'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SevereLimbShortening",
"label": "Severe limb shortening",
"logical_definition": null,
"original_id": "HP:0200083",
"relationships": [
{
"predicate": "subClassOf",
"target": "Micromelia"
}
]
}
| 0 |
{
"document": "Severe limb shortening None [{'predicate': 'subClassOf', 'target': 'Micromelia'}]"
}
|
{
"aliases": null,
"definition": "A severe degree of muscular hypotonia characterized by markedly reduced muscle tone.",
"id": "SevereMuscularHypotonia",
"label": "Severe muscular hypotonia",
"logical_definition": null,
"original_id": "HP:0006829",
"relationships": [
{
"predicate": "subClassOf",
"target": "Hypotonia"
}
]
}
| 0 |
{
"document": "Severe muscular hypotonia A severe degree of muscular hypotonia characterized by markedly reduced muscle tone. [{'predicate': 'subClassOf', 'target': 'Hypotonia'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe course of infection with Human norovirus, previously known as Norwalk virus. Norovirus, an RNA virus of the family Caliciviridae, is a human enteric pathogen. Norovirus infection-associated illness may also be more prolonged and severe in immunocompromised individuals and may be associated with remarkably persistent viral excretion in some of these individuals.",
"id": "SevereNorovirusInfection",
"label": "Severe norovirus infection",
"logical_definition": null,
"original_id": "HP:0020099",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereInfection"
}
]
}
| 0 |
{
"document": "Severe norovirus infection An unusually severe course of infection with Human norovirus, previously known as Norwalk virus. Norovirus, an RNA virus of the family Caliciviridae, is a human enteric pathogen. Norovirus infection-associated illness may also be more prolonged and severe in immunocompromised individuals and may be associated with remarkably persistent viral excretion in some of these individuals. [{'predicate': 'subClassOf', 'target': 'SevereInfection'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe infection by a parainfluenza virus.",
"id": "SevereParainfluenzaInfection",
"label": "Severe parainfluenza infection",
"logical_definition": null,
"original_id": "HP:0031695",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereViralInfection"
}
]
}
| 0 |
{
"document": "Severe parainfluenza infection An unusually severe infection by a parainfluenza virus. [{'predicate': 'subClassOf', 'target': 'SevereViralInfection'}]"
}
|
{
"aliases": null,
"definition": "A severe form of periodontitis.",
"id": "SeverePeriodontitis",
"label": "Severe periodontitis",
"logical_definition": null,
"original_id": "HP:0000166",
"relationships": [
{
"predicate": "subClassOf",
"target": "Periodontitis"
}
]
}
| 0 |
{
"document": "Severe periodontitis A severe form of periodontitis. [{'predicate': 'subClassOf', 'target': 'Periodontitis'}]"
}
|
{
"aliases": null,
"definition": "A severe degree of photosensitivity of the skin.",
"id": "SeverePhotosensitivity",
"label": "Severe photosensitivity",
"logical_definition": null,
"original_id": "HP:0007537",
"relationships": [
{
"predicate": "subClassOf",
"target": "CutaneousPhotosensitivity"
}
]
}
| 0 |
{
"document": "Severe photosensitivity A severe degree of photosensitivity of the skin. [{'predicate': 'subClassOf', 'target': 'CutaneousPhotosensitivity'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SeverePlatyspondyly",
"label": "Severe platyspondyly",
"logical_definition": null,
"original_id": "HP:0004565",
"relationships": [
{
"predicate": "subClassOf",
"target": "Platyspondyly"
}
]
}
| 0 |
{
"document": "Severe platyspondyly None [{'predicate': 'subClassOf', 'target': 'Platyspondyly'}]"
}
|
{
"aliases": null,
"definition": "Severely slow or limited growth after birth, being four standard deviations or more below age- and sex-related norms.",
"id": "SeverePostnatalGrowthRetardation",
"label": "Severe postnatal growth retardation",
"logical_definition": null,
"original_id": "HP:0008850",
"relationships": [
{
"predicate": "subClassOf",
"target": "PostnatalGrowthRetardation"
}
]
}
| 0 |
{
"document": "Severe postnatal growth retardation Severely slow or limited growth after birth, being four standard deviations or more below age- and sex-related norms. [{'predicate': 'subClassOf', 'target': 'PostnatalGrowthRetardation'}]"
}
|
{
"aliases": null,
"definition": "A severe delay in the acquisition of the ability to understand the speech of others.",
"id": "SevereReceptiveLanguageDelay",
"label": "Severe receptive language delay",
"logical_definition": null,
"original_id": "HP:0011352",
"relationships": [
{
"predicate": "subClassOf",
"target": "ReceptiveLanguageDelay"
}
]
}
| 0 |
{
"document": "Severe receptive language delay A severe delay in the acquisition of the ability to understand the speech of others. [{'predicate': 'subClassOf', 'target': 'ReceptiveLanguageDelay'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SevereRecurrentVaricella",
"label": "Severe recurrent varicella",
"logical_definition": null,
"original_id": "HP:0005428",
"relationships": [
{
"predicate": "subClassOf",
"target": "RecurrentViralInfections"
}
]
}
| 0 |
{
"document": "Severe recurrent varicella None [{'predicate': 'subClassOf', 'target': 'RecurrentViralInfections'}]"
}
|
{
"aliases": null,
"definition": "Unusually severe clinical course of SARS-CoV-2 infection, manifested clinically by features such as dyspnea and hypoxia with diffuse bilateral ground-glass opacities of the lungs on computed tomographic scan with progressive respiratory insufficiency necessitating oxygen supplementation or mechanical ventilation.",
"id": "SevereSARSCoV2Infection",
"label": "Severe SARS-CoV-2 infection",
"logical_definition": null,
"original_id": "HP:0033141",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereViralInfection"
}
]
}
| 0 |
{
"document": "Severe SARS-CoV-2 infection Unusually severe clinical course of SARS-CoV-2 infection, manifested clinically by features such as dyspnea and hypoxia with diffuse bilateral ground-glass opacities of the lungs on computed tomographic scan with progressive respiratory insufficiency necessitating oxygen supplementation or mechanical ventilation. [{'predicate': 'subClassOf', 'target': 'SevereViralInfection'}]"
}
|
{
"aliases": null,
"definition": "A severe form of sensorineural hearing impairment.",
"id": "SevereSensorineuralHearingImpairment",
"label": "Severe sensorineural hearing impairment",
"logical_definition": null,
"original_id": "HP:0008625",
"relationships": [
{
"predicate": "subClassOf",
"target": "SensorineuralHearingImpairment"
},
{
"predicate": "subClassOf",
"target": "SevereHearingImpairment"
}
]
}
| 0 |
{
"document": "Severe sensorineural hearing impairment A severe form of sensorineural hearing impairment. [{'predicate': 'subClassOf', 'target': 'SensorineuralHearingImpairment'}, {'predicate': 'subClassOf', 'target': 'SevereHearingImpairment'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SevereShortLimbDwarfism",
"label": "Severe short-limb dwarfism",
"logical_definition": null,
"original_id": "HP:0008890",
"relationships": [
{
"predicate": "subClassOf",
"target": "DisproportionateShortLimbShortStature"
}
]
}
| 0 |
{
"document": "Severe short-limb dwarfism None [{'predicate': 'subClassOf', 'target': 'DisproportionateShortLimbShortStature'}]"
}
|
{
"aliases": null,
"definition": "A severe degree of short stature, more than -4 SD from the mean corrected for age and sex.",
"id": "SevereShortStature",
"label": "Severe short stature",
"logical_definition": null,
"original_id": "HP:0003510",
"relationships": [
{
"predicate": "subClassOf",
"target": "ProportionateShortStature"
}
]
}
| 0 |
{
"document": "Severe short stature A severe degree of short stature, more than -4 SD from the mean corrected for age and sex. [{'predicate': 'subClassOf', 'target': 'ProportionateShortStature'}]"
}
|
{
"aliases": null,
"definition": "A primary immune deficiency that is characterized by defects or deficiencies of T-lymphocytes that causes specific susceptibility to intracellular micro-organisms.",
"id": "SevereTCellImmunodeficiency",
"label": "Severe T-cell immunodeficiency",
"logical_definition": null,
"original_id": "HP:0005352",
"relationships": [
{
"predicate": "subClassOf",
"target": "CellularImmunodeficiency"
}
]
}
| 0 |
{
"document": "Severe T-cell immunodeficiency A primary immune deficiency that is characterized by defects or deficiencies of T-lymphocytes that causes specific susceptibility to intracellular micro-organisms. [{'predicate': 'subClassOf', 'target': 'CellularImmunodeficiency'}]"
}
|
{
"aliases": null,
"definition": "Temper tantrums whose severity is more severe than usual. For instance, a temper tantrum might be considered to be severe if a child loses control so completely that the child cannot control the tantrum on its own, continuing until it becomes exhausted or a parent intervenes.",
"id": "SevereTemperTantrums",
"label": "Severe temper tantrums",
"logical_definition": null,
"original_id": "HP:0025162",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalTemperTantrums"
}
]
}
| 0 |
{
"document": "Severe temper tantrums Temper tantrums whose severity is more severe than usual. For instance, a temper tantrum might be considered to be severe if a child loses control so completely that the child cannot control the tantrum on its own, continuing until it becomes exhausted or a parent intervenes. [{'predicate': 'subClassOf', 'target': 'AbnormalTemperTantrums'}]"
}
|
{
"aliases": null,
"definition": "Toxoplasmosis is a widespread parasitic infection that is frequently asymptomatic in immunocompetent patients. However, this obligate intracellular protozoan parasite can evade the immune system and persist for the life of its host in cyst form, predominantly in the brain, retina, and muscles. Reactivation of latent cysts may occur when the immune system fails to maintain cytokine pressure, which mainly relies on gamma interferon (IFN-gamma). Toxoplasmosis is a life-threatening infection in immunocompromised patients (ICPs).",
"id": "SevereToxoplasmosis",
"label": "Severe toxoplasmosis",
"logical_definition": null,
"original_id": "HP:0020105",
"relationships": [
{
"predicate": "subClassOf",
"target": "UnusualProtozoanInfection"
}
]
}
| 0 |
{
"document": "Severe toxoplasmosis Toxoplasmosis is a widespread parasitic infection that is frequently asymptomatic in immunocompetent patients. However, this obligate intracellular protozoan parasite can evade the immune system and persist for the life of its host in cyst form, predominantly in the brain, retina, and muscles. Reactivation of latent cysts may occur when the immune system fails to maintain cytokine pressure, which mainly relies on gamma interferon (IFN-gamma). Toxoplasmosis is a life-threatening infection in immunocompromised patients (ICPs). [{'predicate': 'subClassOf', 'target': 'UnusualProtozoanInfection'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe form of varicella zoster virus (VZV) infection. In the majority of the cases, especially in children, varicella is a very mild infection characterised by skin lesions, low grade fever and malaise. Severe infection is characterized by manifestions including VZV pneumonia, hepatitis, meningitis, and disseminated varicella.",
"id": "SevereVaricellaZosterInfection",
"label": "Severe varicella zoster infection",
"logical_definition": null,
"original_id": "HP:0032170",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereViralInfection"
}
]
}
| 0 |
{
"document": "Severe varicella zoster infection An unusually severe form of varicella zoster virus (VZV) infection. In the majority of the cases, especially in children, varicella is a very mild infection characterised by skin lesions, low grade fever and malaise. Severe infection is characterized by manifestions including VZV pneumonia, hepatitis, meningitis, and disseminated varicella. [{'predicate': 'subClassOf', 'target': 'SevereViralInfection'}]"
}
|
{
"aliases": null,
"definition": "An unusually severe viral infection.",
"id": "SevereViralInfection",
"label": "Severe viral infection",
"logical_definition": null,
"original_id": "HP:0031691",
"relationships": [
{
"predicate": "subClassOf",
"target": "SevereInfection"
}
]
}
| 0 |
{
"document": "Severe viral infection An unusually severe viral infection. [{'predicate': 'subClassOf', 'target': 'SevereInfection'}]"
}
|
{
"aliases": null,
"definition": "A severe reduction in the ability to perceive visual contrast characterized by 1.00 log unit or more contrast sensitivity loss.",
"id": "SeverelyReducedContrastSensitivity",
"label": "Severely reduced contrast sensitivity",
"logical_definition": null,
"original_id": "HP:0032110",
"relationships": [
{
"predicate": "subClassOf",
"target": "ReducedContrastSensitivity"
}
]
}
| 0 |
{
"document": "Severely reduced contrast sensitivity A severe reduction in the ability to perceive visual contrast characterized by 1.00 log unit or more contrast sensitivity loss. [{'predicate': 'subClassOf', 'target': 'ReducedContrastSensitivity'}]"
}
|
{
"aliases": null,
"definition": "A large reduction in the fraction of blood pumped from the left ventricle with each cardiac cycle. The normal range in adults is at over 50 percent, and a severe reduction is defined as less than 30 percent.",
"id": "SeverelyReducedLeftVentricularEjectionFraction",
"label": "Severely reduced left ventricular ejection fraction",
"logical_definition": null,
"original_id": "HP:0012666",
"relationships": [
{
"predicate": "subClassOf",
"target": "ReducedLeftVentricularEjectionFraction"
}
]
}
| 0 |
{
"document": "Severely reduced left ventricular ejection fraction A large reduction in the fraction of blood pumped from the left ventricle with each cardiac cycle. The normal range in adults is at over 50 percent, and a severe reduction is defined as less than 30 percent. [{'predicate': 'subClassOf', 'target': 'ReducedLeftVentricularEjectionFraction'}]"
}
|
{
"aliases": null,
"definition": "Severe reduction of the ability to see defined as visual acuity less than 6/60 (20/200 in US notation; 0.1 in decimal notation) but at least 3/60 (20/400 in US notation; 0.05 in decimal notation).",
"id": "SeverelyReducedVisualAcuity",
"label": "Severely reduced visual acuity",
"logical_definition": null,
"original_id": "HP:0001141",
"relationships": [
{
"predicate": "subClassOf",
"target": "ReducedVisualAcuity"
}
]
}
| 0 |
{
"document": "Severely reduced visual acuity Severe reduction of the ability to see defined as visual acuity less than 6/60 (20/200 in US notation; 0.1 in decimal notation) but at least 3/60 (20/400 in US notation; 0.05 in decimal notation). [{'predicate': 'subClassOf', 'target': 'ReducedVisualAcuity'}]"
}
|
{
"aliases": null,
"definition": "The intensity or degree of a manifestation.",
"id": "Severity",
"label": "Severity",
"logical_definition": null,
"original_id": "HP:0012824",
"relationships": [
{
"predicate": "subClassOf",
"target": "ClinicalModifier"
}
]
}
| 0 |
{
"document": "Severity The intensity or degree of a manifestation. [{'predicate': 'subClassOf', 'target': 'ClinicalModifier'}]"
}
|
{
"aliases": null,
"definition": "Cordlike masses of epithelial tissue that invaginate from germinal epithelium of the gonad and give rise to seminiferous tubules and rete testes in the male, and primary ovarian follicles and rete ovarii in the female.",
"id": "SexCord",
"label": "sex cord",
"logical_definition": null,
"original_id": "UBERON:0005295",
"relationships": [
{
"predicate": "PartOf",
"target": "Embryo"
},
{
"predicate": "DevelopsFrom",
"target": "GonadalRidge"
},
{
"predicate": "subClassOf",
"target": "EpithelialCord"
}
]
}
| 0 |
{
"document": "sex cord Cordlike masses of epithelial tissue that invaginate from germinal epithelium of the gonad and give rise to seminiferous tubules and rete testes in the male, and primary ovarian follicles and rete ovarii in the female. [{'predicate': 'PartOf', 'target': 'Embryo'}, {'predicate': 'DevelopsFrom', 'target': 'GonadalRidge'}, {'predicate': 'subClassOf', 'target': 'EpithelialCord'}]"
}
|
{
"aliases": null,
"definition": "The establishment of the sex of an organism by physical differentiation.",
"id": "SexDifferentiation",
"label": "sex differentiation",
"logical_definition": null,
"original_id": "GO:0007548",
"relationships": [
{
"predicate": "subClassOf",
"target": "DevelopmentalProcessInvolvedInReproduction"
}
]
}
| 0 |
{
"document": "sex differentiation The establishment of the sex of an organism by physical differentiation. [{'predicate': 'subClassOf', 'target': 'DevelopmentalProcessInvolvedInReproduction'}]"
}
|
{
"aliases": null,
"definition": "Any hormone that is responsible for controlling sexual characteristics and reproductive function.",
"id": "SexHormone",
"label": "sex hormone",
"logical_definition": null,
"original_id": "CHEBI:50112",
"relationships": [
{
"predicate": "subClassOf",
"target": "Hormone"
}
]
}
| 0 |
{
"document": "sex hormone Any hormone that is responsible for controlling sexual characteristics and reproductive function. [{'predicate': 'subClassOf', 'target': 'Hormone'}]"
}
|
{
"aliases": null,
"definition": "Sex limitation is used to refer to a monogenic trait linked to an autosomal locus in which the phenotypic effects of allelic differences are expressed only in one sex.",
"id": "SexLimitedExpression",
"label": "Sex-limited expression",
"logical_definition": null,
"original_id": "HP:0001470",
"relationships": [
{
"predicate": "subClassOf",
"target": "InheritanceModifier"
}
]
}
| 0 |
{
"document": "Sex-limited expression Sex limitation is used to refer to a monogenic trait linked to an autosomal locus in which the phenotypic effects of allelic differences are expressed only in one sex. [{'predicate': 'subClassOf', 'target': 'InheritanceModifier'}]"
}
|
{
"aliases": null,
"definition": "Development of the reproductive system is inconsistent with the chromosomal sex.",
"id": "SexReversal",
"label": "Sex reversal",
"logical_definition": null,
"original_id": "HP:0012245",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalSexDetermination"
}
]
}
| 0 |
{
"document": "Sex reversal Development of the reproductive system is inconsistent with the chromosomal sex. [{'predicate': 'subClassOf', 'target': 'AbnormalSexDetermination'}]"
}
|
{
"aliases": null,
"definition": "A part of the body present only in a specific gender.",
"id": "SexSpecificAnatomicalStructure",
"label": "sex-specific anatomical structure",
"logical_definition": null,
"original_id": "UBERON:0014402",
"relationships": null
}
| 0 |
{
"document": "sex-specific anatomical structure A part of the body present only in a specific gender. None"
}
|
{
"aliases": null,
"definition": "Behaviour related to the activity which primary purpose is the sexual reproduction.",
"id": "SexualActivity",
"label": "sexual activity",
"logical_definition": null,
"original_id": "NBO:0000034",
"relationships": [
{
"predicate": "subClassOf",
"target": "ReproductiveBehavior_NBO:0000010"
}
]
}
| 0 |
{
"document": "sexual activity Behaviour related to the activity which primary purpose is the sexual reproduction. [{'predicate': 'subClassOf', 'target': 'ReproductiveBehavior_NBO:0000010'}]"
}
|
{
"aliases": null,
"definition": "Observable characteristic of behavior related to the activity which primary purpose is the sexual reproduction.",
"id": "SexualActivityPhenotype",
"label": "sexual activity phenotype",
"logical_definition": null,
"original_id": "NBO:0000758",
"relationships": [
{
"predicate": "subClassOf",
"target": "ReproductiveBehaviorPhenotype"
}
]
}
| 0 |
{
"document": "sexual activity phenotype Observable characteristic of behavior related to the activity which primary purpose is the sexual reproduction. [{'predicate': 'subClassOf', 'target': 'ReproductiveBehaviorPhenotype'}]"
}
|
{
"aliases": null,
"definition": "\"A social behavior characterised by conscious or unconscious constraint or curtailment of behavior relating to specific sexual matters or practices.\" [wikipedia:Sexual_inhibition]",
"id": "SexualInhibition",
"label": "sexual inhibition",
"logical_definition": null,
"original_id": "NBO:0000605",
"relationships": [
{
"predicate": "subClassOf",
"target": "SocialBehavior_NBO:0000011"
}
]
}
| 0 |
{
"document": "sexual inhibition \"A social behavior characterised by conscious or unconscious constraint or curtailment of behavior relating to specific sexual matters or practices.\" [wikipedia:Sexual_inhibition] [{'predicate': 'subClassOf', 'target': 'SocialBehavior_NBO:0000011'}]"
}
|
{
"aliases": null,
"definition": "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid).",
"id": "SexualReproduction",
"label": "sexual reproduction",
"logical_definition": null,
"original_id": "GO:0019953",
"relationships": [
{
"predicate": "subClassOf",
"target": "Reproduction"
}
]
}
| 0 |
{
"document": "sexual reproduction A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). [{'predicate': 'subClassOf', 'target': 'Reproduction'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SexuallyHomologousTo",
"label": "sexually_homologous_to",
"logical_definition": null,
"original_id": "obo:uberon/core#sexually_homologous_to",
"relationships": [
{
"predicate": "subPropertyOf",
"target": "SharesAncestorWith"
}
]
}
| 0 |
{
"document": "sexually_homologous_to None [{'predicate': 'subPropertyOf', 'target': 'SharesAncestorWith'}]"
}
|
{
"aliases": null,
"definition": "A multicellular organism that is at the juvenile stage.",
"id": "SexuallyImmatureOrganism",
"label": "sexually immature organism",
"logical_definition": null,
"original_id": "UBERON:0007021",
"relationships": [
{
"predicate": "HasQuality",
"target": "Juvenile"
}
]
}
| 0 |
{
"document": "sexually immature organism A multicellular organism that is at the juvenile stage. [{'predicate': 'HasQuality', 'target': 'Juvenile'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "SexuallyImmatureStage",
"label": "sexually immature stage",
"logical_definition": null,
"original_id": "UBERON:0000112",
"relationships": [
{
"predicate": "PartOf",
"target": "FullyFormedStage"
},
{
"predicate": "subClassOf",
"target": "LifeCycleStage"
}
]
}
| 0 |
{
"document": "sexually immature stage None [{'predicate': 'PartOf', 'target': 'FullyFormedStage'}, {'predicate': 'subClassOf', 'target': 'LifeCycleStage'}]"
}
|
{
"aliases": null,
"definition": "A plaque representing a connective-tissue nevus. Connective tissue naevi are uncommon skin lesions that occur when the deeper layers of the skin do not develop correctly or the components of these layers occur in the wrong proportion. Shagreen patches are oval-shaped and nevoid, skin-colored or occasionally pigmented, smooth or crinkled. The word shagreen refers to a type of roughened untanned leather.",
"id": "ShagreenPatch",
"label": "Shagreen patch",
"logical_definition": null,
"original_id": "HP:0009721",
"relationships": [
{
"predicate": "subClassOf",
"target": "ConnectiveTissueNevi"
}
]
}
| 0 |
{
"document": "Shagreen patch A plaque representing a connective-tissue nevus. Connective tissue naevi are uncommon skin lesions that occur when the deeper layers of the skin do not develop correctly or the components of these layers occur in the wrong proportion. Shagreen patches are oval-shaped and nevoid, skin-colored or occasionally pigmented, smooth or crinkled. The word shagreen refers to a type of roughened untanned leather. [{'predicate': 'subClassOf', 'target': 'ConnectiveTissueNevi'}]"
}
|
{
"aliases": null,
"definition": null,
"id": "ShallowAcetabularFossae",
"label": "Shallow acetabular fossae",
"logical_definition": null,
"original_id": "HP:0003182",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalAcetabulumMorphology"
}
]
}
| 0 |
{
"document": "Shallow acetabular fossae None [{'predicate': 'subClassOf', 'target': 'AbnormalAcetabulumMorphology'}]"
}
|
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