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{ "aliases": null, "definition": null, "id": "ThyroidFollicularAdenoma", "label": "Thyroid follicular adenoma", "logical_definition": null, "original_id": "HP:0011774", "relationships": [ { "predicate": "subClassOf", "target": "ThyroidAdenoma" } ] }
0
{ "document": "Thyroid follicular adenoma None [{'predicate': 'subClassOf', 'target': 'ThyroidAdenoma'}]" }
{ "aliases": null, "definition": "A cell type that varies from squamous to columnar, depending on their activity with microvillus directed luminally. This cell produces and secretes thyroid hormones.", "id": "ThyroidFollicularCell", "label": "thyroid follicular cell", "logical_definition": null, "original_id": "CL:0002258", "relationships": [ { "predicate": "subClassOf", "target": "EpithelialCellOfThyroidGland" } ] }
0
{ "document": "thyroid follicular cell A cell type that varies from squamous to columnar, depending on their activity with microvillus directed luminally. This cell produces and secretes thyroid hormones. [{'predicate': 'subClassOf', 'target': 'EpithelialCellOfThyroidGland'}]" }
{ "aliases": null, "definition": null, "id": "ThyroidFollicularHyperplasia", "label": "Thyroid follicular hyperplasia", "logical_definition": null, "original_id": "HP:0008225", "relationships": [ { "predicate": "subClassOf", "target": "ThyroidHyperplasia" } ] }
0
{ "document": "Thyroid follicular hyperplasia None [{'predicate': 'subClassOf', 'target': 'ThyroidHyperplasia'}]" }
{ "aliases": null, "definition": "A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO].", "id": "ThyroidGland", "label": "thyroid gland", "logical_definition": null, "original_id": "UBERON:0002046", "relationships": [ { "predicate": "PartOf", "target": "EndocrineSystem" }, { "predicate": "ContainsProcess", "target": "ThyroidHormoneGeneration" }, { "predicate": "CapableOf", "target": "CalcitoninSecretion" }, { "predicate": "CapableOfPartOf", "target": "CalciumIonHomeostasis" }, { "predicate": "HasDevelopmentalContributionFrom", "target": "NeuralCrest" }, { "predicate": "TransformationOf", "target": "ThyroidDiverticulum" }, { "predicate": "subClassOf", "target": "Gland" } ] }
0
{ "document": "thyroid gland A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]. [{'predicate': 'PartOf', 'target': 'EndocrineSystem'}, {'predicate': 'ContainsProcess', 'target': 'ThyroidHormoneGeneration'}, {'predicate': 'CapableOf', 'target': 'CalcitoninSecretion'}, {'predicate': 'CapableOfPartOf', 'target': 'CalciumIonHomeostasis'}, {'predicate': 'HasDevelopmentalContributionFrom', 'target': 'NeuralCrest'}, {'predicate': 'TransformationOf', 'target': 'ThyroidDiverticulum'}, {'predicate': 'subClassOf', 'target': 'Gland'}]" }
{ "aliases": null, "definition": "A medulla that is part of a thyroid [Automatically generated definition].", "id": "ThyroidGlandMedulla", "label": "thyroid gland medulla", "logical_definition": null, "original_id": "UBERON:0004827", "relationships": null }
0
{ "document": "thyroid gland medulla A medulla that is part of a thyroid [Automatically generated definition]. None" }
{ "aliases": null, "definition": "Absence of a lobe of the thyroid gland related to a failure of its embryologic development.", "id": "ThyroidHemiagenesis", "label": "Thyroid hemiagenesis", "logical_definition": null, "original_id": "HP:0011780", "relationships": [ { "predicate": "subClassOf", "target": "AplasiaHypoplasiaOfTheThyroidGland" } ] }
0
{ "document": "Thyroid hemiagenesis Absence of a lobe of the thyroid gland related to a failure of its embryologic development. [{'predicate': 'subClassOf', 'target': 'AplasiaHypoplasiaOfTheThyroidGland'}]" }
{ "aliases": null, "definition": "Any hormone produced by the thyroid gland", "id": "ThyroidHormone", "label": "thyroid hormone", "logical_definition": null, "original_id": "CHEBI:60311", "relationships": [ { "predicate": "subClassOf", "target": "Hormone" } ] }
0
{ "document": "thyroid hormone Any hormone produced by the thyroid gland [{'predicate': 'subClassOf', 'target': 'Hormone'}]" }
{ "aliases": null, "definition": "The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.", "id": "ThyroidHormoneGeneration", "label": "thyroid hormone generation", "logical_definition": null, "original_id": "GO:0006590", "relationships": [ { "predicate": "subClassOf", "target": "ThyroidHormoneMetabolicProcess" } ] }
0
{ "document": "thyroid hormone generation The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones. [{'predicate': 'subClassOf', 'target': 'ThyroidHormoneMetabolicProcess'}]" }
{ "aliases": null, "definition": "The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.", "id": "ThyroidHormoneMetabolicProcess", "label": "thyroid hormone metabolic process", "logical_definition": null, "original_id": "GO:0042403", "relationships": [ { "predicate": "subClassOf", "target": "CellularModifiedAminoAcidMetabolicProcess" }, { "predicate": "subClassOf", "target": "PhenolContainingCompoundMetabolicProcess" }, { "predicate": "subClassOf", "target": "HormoneMetabolicProcess" } ] }
0
{ "document": "thyroid hormone metabolic process The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. [{'predicate': 'subClassOf', 'target': 'CellularModifiedAminoAcidMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'PhenolContainingCompoundMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'HormoneMetabolicProcess'}]" }
{ "aliases": null, "definition": "Hyperplasia of the thyroid gland.", "id": "ThyroidHyperplasia", "label": "Thyroid hyperplasia", "logical_definition": null, "original_id": "HP:0008249", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalThyroidMorphology" } ] }
0
{ "document": "Thyroid hyperplasia Hyperplasia of the thyroid gland. [{'predicate': 'subClassOf', 'target': 'AbnormalThyroidMorphology'}]" }
{ "aliases": null, "definition": "Developmental hypoplasia of the thyroid gland.", "id": "ThyroidHypoplasia", "label": "Thyroid hypoplasia", "logical_definition": null, "original_id": "HP:0005990", "relationships": [ { "predicate": "subClassOf", "target": "AplasiaHypoplasiaOfTheThyroidGland" } ] }
0
{ "document": "Thyroid hypoplasia Developmental hypoplasia of the thyroid gland. [{'predicate': 'subClassOf', 'target': 'AplasiaHypoplasiaOfTheThyroidGland'}]" }
{ "aliases": null, "definition": "The presence of lymphangiectasis of the thyroid gland.", "id": "ThyroidLymphangiectasia", "label": "Thyroid lymphangiectasia", "logical_definition": null, "original_id": "HP:0008229", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalThyroidMorphology" }, { "predicate": "subClassOf", "target": "Lymphangiectasis" } ] }
0
{ "document": "Thyroid lymphangiectasia The presence of lymphangiectasis of the thyroid gland. [{'predicate': 'subClassOf', 'target': 'AbnormalThyroidMorphology'}, {'predicate': 'subClassOf', 'target': 'Lymphangiectasis'}]" }
{ "aliases": null, "definition": null, "id": "ThyroidMacrofollicularAdenoma", "label": "Thyroid macrofollicular adenoma", "logical_definition": null, "original_id": "HP:0011775", "relationships": [ { "predicate": "subClassOf", "target": "ThyroidFollicularAdenoma" } ] }
0
{ "document": "Thyroid macrofollicular adenoma None [{'predicate': 'subClassOf', 'target': 'ThyroidFollicularAdenoma'}]" }
{ "aliases": null, "definition": null, "id": "ThyroidMicrofollicularAdenoma", "label": "Thyroid microfollicular adenoma", "logical_definition": null, "original_id": "HP:0011776", "relationships": [ { "predicate": "subClassOf", "target": "ThyroidFollicularAdenoma" } ] }
0
{ "document": "Thyroid microfollicular adenoma None [{'predicate': 'subClassOf', 'target': 'ThyroidFollicularAdenoma'}]" }
{ "aliases": null, "definition": "A nodular lesion that develops in the thyroid gland. The term \"thyroid nodule\" refers to any abnormal growth that forms a lump in the thyroid gland.", "id": "ThyroidNodule", "label": "Thyroid nodule", "logical_definition": null, "original_id": "HP:0025388", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalThyroidMorphology" } ] }
0
{ "document": "Thyroid nodule A nodular lesion that develops in the thyroid gland. The term \"thyroid nodule\" refers to any abnormal growth that forms a lump in the thyroid gland. [{'predicate': 'subClassOf', 'target': 'AbnormalThyroidMorphology'}]" }
{ "aliases": null, "definition": null, "id": "ThyroidPapillaryAdenoma", "label": "Thyroid papillary adenoma", "logical_definition": null, "original_id": "HP:0011777", "relationships": [ { "predicate": "subClassOf", "target": "ThyroidAdenoma" } ] }
0
{ "document": "Thyroid papillary adenoma None [{'predicate': 'subClassOf', 'target': 'ThyroidAdenoma'}]" }
{ "aliases": null, "definition": null, "id": "ThyroidPreCartilageCondensation", "label": "thyroid pre-cartilage condensation", "logical_definition": null, "original_id": "UBERON:0010219", "relationships": [ { "predicate": "subClassOf", "target": "LaryngealPreCartilageCondensation" } ] }
0
{ "document": "thyroid pre-cartilage condensation None [{'predicate': 'subClassOf', 'target': 'LaryngealPreCartilageCondensation'}]" }
{ "aliases": null, "definition": "The initial thyroid precursor, the thyroid primordium, starts as a simple midline thickening and develops to form the thyroid diverticulum. This structure is initially hollow, although it later solidifies and becomes bilobed. The 2 lobes are located on either side of the midline and are connected via an isthmus.", "id": "ThyroidPrimordium", "label": "thyroid primordium", "logical_definition": null, "original_id": "UBERON:0003091", "relationships": [ { "predicate": "PartOf", "target": "EndocrineSystem" }, { "predicate": "PartOf", "target": "ChordatePharynx" }, { "predicate": "DevelopsFrom", "target": "PharyngealPouch2" }, { "predicate": "subClassOf", "target": "Tissue" }, { "predicate": "subClassOf", "target": "Primordium" } ] }
0
{ "document": "thyroid primordium The initial thyroid precursor, the thyroid primordium, starts as a simple midline thickening and develops to form the thyroid diverticulum. This structure is initially hollow, although it later solidifies and becomes bilobed. The 2 lobes are located on either side of the midline and are connected via an isthmus. [{'predicate': 'PartOf', 'target': 'EndocrineSystem'}, {'predicate': 'PartOf', 'target': 'ChordatePharynx'}, {'predicate': 'DevelopsFrom', 'target': 'PharyngealPouch2'}, {'predicate': 'subClassOf', 'target': 'Tissue'}, {'predicate': 'subClassOf', 'target': 'Primordium'}]" }
{ "aliases": null, "definition": "An endoderm that is part of a thyroid primordium.", "id": "ThyroidPrimordiumEndoderm", "label": "thyroid primordium endoderm", "logical_definition": null, "original_id": "UBERON:0003261", "relationships": [ { "predicate": "DevelopsFrom", "target": "EarlyPharyngealEndoderm" } ] }
0
{ "document": "thyroid primordium endoderm An endoderm that is part of a thyroid primordium. [{'predicate': 'DevelopsFrom', 'target': 'EarlyPharyngealEndoderm'}]" }
{ "aliases": null, "definition": "A vein that drains a thyroid gland.", "id": "ThyroidVein", "label": "thyroid vein", "logical_definition": null, "original_id": "UBERON:0018246", "relationships": null }
0
{ "document": "thyroid vein A vein that drains a thyroid gland. None" }
{ "aliases": null, "definition": "Inflammation of the thyroid gland.", "id": "Thyroiditis", "label": "Thyroiditis", "logical_definition": null, "original_id": "HP:0100646", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalThyroidMorphology" }, { "predicate": "subClassOf", "target": "IncreasedInflammatoryResponse" } ] }
0
{ "document": "Thyroiditis Inflammation of the thyroid gland. [{'predicate': 'subClassOf', 'target': 'AbnormalThyroidMorphology'}, {'predicate': 'subClassOf', 'target': 'IncreasedInflammatoryResponse'}]" }
{ "aliases": null, "definition": "A type of renal tubular atrophy characterized by a thyroid-like appearance, with small round tubules with markedly flattened, simplified epithelium and uniform intratubular casts.", "id": "ThyroidizationTypeTubularAtrophy", "label": "Thyroidization-type tubular atrophy", "logical_definition": null, "original_id": "HP:0032608", "relationships": [ { "predicate": "subClassOf", "target": "RenalTubularAtrophy" } ] }
0
{ "document": "Thyroidization-type tubular atrophy A type of renal tubular atrophy characterized by a thyroid-like appearance, with small round tubules with markedly flattened, simplified epithelium and uniform intratubular casts. [{'predicate': 'subClassOf', 'target': 'RenalTubularAtrophy'}]" }
{ "aliases": null, "definition": "A tyrosine derivative where the phenolic hydrogen of tyrosine is substituted by 4-hydroxyphenyl.", "id": "Thyronine", "label": "thyronine", "logical_definition": null, "original_id": "CHEBI:30661", "relationships": [ { "predicate": "subClassOf", "target": "Phenols" }, { "predicate": "subClassOf", "target": "TyrosineDerivative" }, { "predicate": "subClassOf", "target": "NonProteinogenicAlphaAminoAcid" } ] }
0
{ "document": "thyronine A tyrosine derivative where the phenolic hydrogen of tyrosine is substituted by 4-hydroxyphenyl. [{'predicate': 'subClassOf', 'target': 'Phenols'}, {'predicate': 'subClassOf', 'target': 'TyrosineDerivative'}, {'predicate': 'subClassOf', 'target': 'NonProteinogenicAlphaAminoAcid'}]" }
{ "aliases": null, "definition": null, "id": "ThyrotoxicosisFromEctopicThyroidTissue", "label": "Thyrotoxicosis from ectopic thyroid tissue", "logical_definition": null, "original_id": "HP:0011783", "relationships": [ { "predicate": "subClassOf", "target": "Hyperthyroidism" } ] }
0
{ "document": "Thyrotoxicosis from ectopic thyroid tissue None [{'predicate': 'subClassOf', 'target': 'Hyperthyroidism'}]" }
{ "aliases": null, "definition": null, "id": "ThyrotoxicosisWithDiffuseGoiter", "label": "Thyrotoxicosis with diffuse goiter", "logical_definition": null, "original_id": "HP:0011784", "relationships": [ { "predicate": "subClassOf", "target": "Hyperthyroidism" } ] }
0
{ "document": "Thyrotoxicosis with diffuse goiter None [{'predicate': 'subClassOf', 'target': 'Hyperthyroidism'}]" }
{ "aliases": null, "definition": null, "id": "ThyrotoxicosisWithToxicMultinodularGoiter", "label": "Thyrotoxicosis with toxic multinodular goiter", "logical_definition": null, "original_id": "HP:0011785", "relationships": [ { "predicate": "subClassOf", "target": "Hyperthyroidism" } ] }
0
{ "document": "Thyrotoxicosis with toxic multinodular goiter None [{'predicate': 'subClassOf', 'target': 'Hyperthyroidism'}]" }
{ "aliases": null, "definition": null, "id": "ThyrotoxicosisWithToxicSingleThyroidNodule", "label": "Thyrotoxicosis with toxic single thyroid nodule", "logical_definition": null, "original_id": "HP:0011786", "relationships": [ { "predicate": "subClassOf", "target": "Hyperthyroidism" } ] }
0
{ "document": "Thyrotoxicosis with toxic single thyroid nodule None [{'predicate': 'subClassOf', 'target': 'Hyperthyroidism'}]" }
{ "aliases": null, "definition": "An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.", "id": "Thyroxine", "label": "thyroxine", "logical_definition": null, "original_id": "CHEBI:30660", "relationships": [ { "predicate": "HasRole", "target": "Mitogen" }, { "predicate": "obo:chebi#is_tautomer_of", "target": "ThyroxineZwitterion" }, { "predicate": "subClassOf", "target": "Iodophenol" }, { "predicate": "subClassOf", "target": "Iodothyronine" }, { "predicate": "subClassOf", "target": "2Halophenol" }, { "predicate": "subClassOf", "target": "TyrosineDerivative" }, { "predicate": "subClassOf", "target": "NonProteinogenicAlphaAminoAcid" } ] }
0
{ "document": "thyroxine An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions. [{'predicate': 'HasRole', 'target': 'Mitogen'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': 'ThyroxineZwitterion'}, {'predicate': 'subClassOf', 'target': 'Iodophenol'}, {'predicate': 'subClassOf', 'target': 'Iodothyronine'}, {'predicate': 'subClassOf', 'target': '2Halophenol'}, {'predicate': 'subClassOf', 'target': 'TyrosineDerivative'}, {'predicate': 'subClassOf', 'target': 'NonProteinogenicAlphaAminoAcid'}]" }
{ "aliases": null, "definition": "The amino acid zwitterion formed from thyroxine by transfer of a proton from the carboxy group to the amino group. Major species at pH 7.3.", "id": "ThyroxineZwitterion", "label": "thyroxine zwitterion", "logical_definition": null, "original_id": "CHEBI:305790", "relationships": [ { "predicate": "obo:chebi#is_tautomer_of", "target": "Thyroxine" }, { "predicate": "subClassOf", "target": "AminoAcidZwitterion" } ] }
0
{ "document": "thyroxine zwitterion The amino acid zwitterion formed from thyroxine by transfer of a proton from the carboxy group to the amino group. Major species at pH 7.3. [{'predicate': 'obo:chebi#is_tautomer_of', 'target': 'Thyroxine'}, {'predicate': 'subClassOf', 'target': 'AminoAcidZwitterion'}]" }
{ "aliases": null, "definition": "The major preaxial endochondral bone in the posterior zeugopod[Phenoscape].", "id": "Tibia", "label": "tibia", "logical_definition": null, "original_id": "UBERON:0000979", "relationships": [ { "predicate": "PartOf", "target": "HindlimbZeugopodSkeleton" }, { "predicate": "PreaxialmostPartOf", "target": "HindlimbZeugopodSkeleton" }, { "predicate": "DevelopsFrom", "target": "TibiaCartilageElement" }, { "predicate": "subClassOf", "target": "LongBone" } ] }
0
{ "document": "tibia The major preaxial endochondral bone in the posterior zeugopod[Phenoscape]. [{'predicate': 'PartOf', 'target': 'HindlimbZeugopodSkeleton'}, {'predicate': 'PreaxialmostPartOf', 'target': 'HindlimbZeugopodSkeleton'}, {'predicate': 'DevelopsFrom', 'target': 'TibiaCartilageElement'}, {'predicate': 'subClassOf', 'target': 'LongBone'}]" }
{ "aliases": null, "definition": "A cartilaginous condensation that has the potential to develop into a tibia.", "id": "TibiaCartilageElement", "label": "tibia cartilage element", "logical_definition": null, "original_id": "UBERON:0010849", "relationships": [ { "predicate": "PartOf", "target": "LowerLegMesenchyme" }, { "predicate": "PartOf", "target": "HindlimbZeugopodSkeleton" }, { "predicate": "DevelopsFrom", "target": "TibiaPreCartilageCondensation" } ] }
0
{ "document": "tibia cartilage element A cartilaginous condensation that has the potential to develop into a tibia. [{'predicate': 'PartOf', 'target': 'LowerLegMesenchyme'}, {'predicate': 'PartOf', 'target': 'HindlimbZeugopodSkeleton'}, {'predicate': 'DevelopsFrom', 'target': 'TibiaPreCartilageCondensation'}]" }
{ "aliases": null, "definition": "The major preaxial endochondral element in the posterior zeugopod[Phenoscape].", "id": "TibiaEndochondralElement", "label": "tibia endochondral element", "logical_definition": null, "original_id": "UBERON:0015004", "relationships": [ { "predicate": "PartOf", "target": "HindlimbZeugopodSkeleton" }, { "predicate": "subClassOf", "target": "EndochondralElement" } ] }
0
{ "document": "tibia endochondral element The major preaxial endochondral element in the posterior zeugopod[Phenoscape]. [{'predicate': 'PartOf', 'target': 'HindlimbZeugopodSkeleton'}, {'predicate': 'subClassOf', 'target': 'EndochondralElement'}]" }
{ "aliases": null, "definition": "A pre-cartilage condensation that has the potential to develop into a tibia.", "id": "TibiaPreCartilageCondensation", "label": "tibia pre-cartilage condensation", "logical_definition": null, "original_id": "UBERON:0010850", "relationships": [ { "predicate": "PartOf", "target": "LowerLegMesenchyme" }, { "predicate": "PartOf", "target": "HindlimbZeugopodSkeleton" } ] }
0
{ "document": "tibia pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a tibia. [{'predicate': 'PartOf', 'target': 'LowerLegMesenchyme'}, {'predicate': 'PartOf', 'target': 'HindlimbZeugopodSkeleton'}]" }
{ "aliases": null, "definition": "An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall of the tibial artery.", "id": "TibialArterialCalcification", "label": "Tibial arterial calcification", "logical_definition": null, "original_id": "HP:0031305", "relationships": [ { "predicate": "subClassOf", "target": "LowerExtremityPeripheralArterialCalcification" } ] }
0
{ "document": "Tibial arterial calcification An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall of the tibial artery. [{'predicate': 'subClassOf', 'target': 'LowerExtremityPeripheralArterialCalcification'}]" }
{ "aliases": null, "definition": "The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and pes. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot.", "id": "TibialArtery", "label": "tibial artery", "logical_definition": null, "original_id": "UBERON:0007610", "relationships": [ { "predicate": "PartOf", "target": "Hindlimb" }, { "predicate": "BranchingPartOf", "target": "PoplitealArtery" }, { "predicate": "subClassOf", "target": "Artery" } ] }
0
{ "document": "tibial artery The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and pes. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot. [{'predicate': 'PartOf', 'target': 'Hindlimb'}, {'predicate': 'BranchingPartOf', 'target': 'PoplitealArtery'}, {'predicate': 'subClassOf', 'target': 'Artery'}]" }
{ "aliases": null, "definition": "A bending or abnormal curvature of the tibia.", "id": "TibialBowing", "label": "Tibial bowing", "logical_definition": null, "original_id": "HP:0002982", "relationships": [ { "predicate": "subClassOf", "target": "BowingOfTheLegs" }, { "predicate": "subClassOf", "target": "AbnormalityOfTibiaMorphology" } ] }
0
{ "document": "Tibial bowing A bending or abnormal curvature of the tibia. [{'predicate': 'subClassOf', 'target': 'BowingOfTheLegs'}, {'predicate': 'subClassOf', 'target': 'AbnormalityOfTibiaMorphology'}]" }
{ "aliases": null, "definition": null, "id": "TibialDeviationOfThe2ndToe", "label": "Tibial deviation of the 2nd toe", "logical_definition": null, "original_id": "HP:0100345", "relationships": [ { "predicate": "subClassOf", "target": "DeviationOfThe2ndToe" } ] }
0
{ "document": "Tibial deviation of the 2nd toe None [{'predicate': 'subClassOf', 'target': 'DeviationOfThe2ndToe'}]" }
{ "aliases": null, "definition": null, "id": "TibialDeviationOfThe3rdToe", "label": "Tibial deviation of the 3rd toe", "logical_definition": null, "original_id": "HP:0100343", "relationships": [ { "predicate": "subClassOf", "target": "DeviationOfThe3rdToe" } ] }
0
{ "document": "Tibial deviation of the 3rd toe None [{'predicate': 'subClassOf', 'target': 'DeviationOfThe3rdToe'}]" }
{ "aliases": null, "definition": null, "id": "TibialDeviationOfThe4thToe", "label": "Tibial deviation of the 4th toe", "logical_definition": null, "original_id": "HP:0100341", "relationships": [ { "predicate": "subClassOf", "target": "DeviationOfThe4thToe" } ] }
0
{ "document": "Tibial deviation of the 4th toe None [{'predicate': 'subClassOf', 'target': 'DeviationOfThe4thToe'}]" }
{ "aliases": null, "definition": null, "id": "TibialDeviationOfThe5thToe", "label": "Tibial deviation of the 5th toe", "logical_definition": null, "original_id": "HP:0100347", "relationships": [ { "predicate": "subClassOf", "target": "DeviationOfThe5thToe" } ] }
0
{ "document": "Tibial deviation of the 5th toe None [{'predicate': 'subClassOf', 'target': 'DeviationOfThe5thToe'}]" }
{ "aliases": null, "definition": null, "id": "TibialDeviationOfToes", "label": "Tibial deviation of toes", "logical_definition": null, "original_id": "HP:0100499", "relationships": [ { "predicate": "subClassOf", "target": "DeviationOfToes" } ] }
0
{ "document": "Tibial deviation of toes None [{'predicate': 'subClassOf', 'target': 'DeviationOfToes'}]" }
{ "aliases": null, "definition": "Irregularity of the normally smooth surface of a metaphysis of a tibia.", "id": "TibialMetaphysealIrregularity", "label": "Tibial metaphyseal irregularity", "logical_definition": null, "original_id": "HP:0030292", "relationships": [ { "predicate": "subClassOf", "target": "LowerLimbMetaphysealIrregularity" } ] }
0
{ "document": "Tibial metaphyseal irregularity Irregularity of the normally smooth surface of a metaphysis of a tibia. [{'predicate': 'subClassOf', 'target': 'LowerLimbMetaphysealIrregularity'}]" }
{ "aliases": null, "definition": "The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted].", "id": "TibialNerve", "label": "tibial nerve", "logical_definition": null, "original_id": "UBERON:0001323", "relationships": [ { "predicate": "PartOf", "target": "Leg" }, { "predicate": "BranchingPartOf", "target": "SciaticNerve" }, { "predicate": "subClassOf", "target": "Nerve" } ] }
0
{ "document": "tibial nerve The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted]. [{'predicate': 'PartOf', 'target': 'Leg'}, {'predicate': 'BranchingPartOf', 'target': 'SciaticNerve'}, {'predicate': 'subClassOf', 'target': 'Nerve'}]" }
{ "aliases": null, "definition": ".", "id": "TibialPlateaux", "label": "tibial plateaux", "logical_definition": null, "original_id": "UBERON:0004098", "relationships": [ { "predicate": "PartOf", "target": "Tibia" }, { "predicate": "subClassOf", "target": "ZoneOfBoneOrgan" } ] }
0
{ "document": "tibial plateaux . [{'predicate': 'PartOf', 'target': 'Tibia'}, {'predicate': 'subClassOf', 'target': 'ZoneOfBoneOrgan'}]" }
{ "aliases": null, "definition": "Pseudarthrosis, or \"false joint\" of the tibia is the result of a developmental failure in the tibia progressing to spontaneous fracture and subsequent fibrous nonunion. The fracture is rarely present at birth but commonly develops during the first 18 months of life.", "id": "TibialPseudarthrosis", "label": "Tibial pseudarthrosis", "logical_definition": null, "original_id": "HP:0009736", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfTibiaMorphology" }, { "predicate": "subClassOf", "target": "Pseudoarthrosis" } ] }
0
{ "document": "Tibial pseudarthrosis Pseudarthrosis, or \"false joint\" of the tibia is the result of a developmental failure in the tibia progressing to spontaneous fracture and subsequent fibrous nonunion. The fracture is rarely present at birth but commonly develops during the first 18 months of life. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTibiaMorphology'}, {'predicate': 'subClassOf', 'target': 'Pseudoarthrosis'}]" }
{ "aliases": null, "definition": "A bony projection (spur, osteophyte) originating from the tibia.", "id": "TibialSpur", "label": "Tibial spur", "logical_definition": null, "original_id": "HP:0031173", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfTibiaMorphology" } ] }
0
{ "document": "Tibial spur A bony projection (spur, osteophyte) originating from the tibia. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTibiaMorphology'}]" }
{ "aliases": null, "definition": "Twisted position of the tibia (shin bone) associated with pathological rotation of the leg.", "id": "TibialTorsion", "label": "Tibial torsion", "logical_definition": null, "original_id": "HP:0100694", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfTibiaMorphology" } ] }
0
{ "document": "Tibial torsion Twisted position of the tibia (shin bone) associated with pathological rotation of the leg. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTibiaMorphology'}]" }
{ "aliases": null, "definition": "The tibial tuberosity is on the anterior side of a tibia and is where a patella ligament attaches.", "id": "TibialTuberosity", "label": "tibial tuberosity", "logical_definition": null, "original_id": "UBERON:7500062", "relationships": null }
0
{ "document": "tibial tuberosity The tibial tuberosity is on the anterior side of a tibia and is where a patella ligament attaches. None" }
{ "aliases": null, "definition": "One of the veins of the lower leg; empty into the popliteal vein.", "id": "TibialVein", "label": "tibial vein", "logical_definition": null, "original_id": "UBERON:0010370", "relationships": [ { "predicate": "PartOf", "target": "Leg" }, { "predicate": "subClassOf", "target": "Vein" } ] }
0
{ "document": "tibial vein One of the veins of the lower leg; empty into the popliteal vein. [{'predicate': 'PartOf', 'target': 'Leg'}, {'predicate': 'subClassOf', 'target': 'Vein'}]" }
{ "aliases": null, "definition": "Either of two muscles of the calf of the leg.", "id": "Tibialis", "label": "tibialis", "logical_definition": null, "original_id": "UBERON:0008230", "relationships": [ { "predicate": "PartOf", "target": "HindlimbZeugopod" }, { "predicate": "subClassOf", "target": "FlexorMuscle" } ] }
0
{ "document": "tibialis Either of two muscles of the calf of the leg. [{'predicate': 'PartOf', 'target': 'HindlimbZeugopod'}, {'predicate': 'subClassOf', 'target': 'FlexorMuscle'}]" }
{ "aliases": null, "definition": "A muscle that originates in the upper two-thirds of the lateral surface of the tibia and inserts into the medial cuneiform and first metatarsal bones of the foot. Its acts to invert the foot. It is situated on the lateral side of the tibia; it is thick and fleshy above, tendinous below. This muscle overlaps the anterior tibial vessels and deep peroneal nerve in the upper part of the leg. [WP,unvetted]. The M. tibialis cranialis is a muscle that flexes the tarsometatarsus. It originates on the craniodistal aspect of the femur and proximal tibiotarsus and inserts on the cranial surface of the tarsometarsus[EvoWiki].", "id": "TibialisAnterior", "label": "tibialis anterior", "logical_definition": null, "original_id": "UBERON:0001385", "relationships": [ { "predicate": "HasMuscleInsertion", "target": "MetatarsalBone" }, { "predicate": "HasMuscleInsertion", "target": "DistalTarsalBone" }, { "predicate": "HasMuscleAntagonist", "target": "Gastrocnemius" }, { "predicate": "HasMuscleAntagonist", "target": "SoleusMuscle" }, { "predicate": "HasMuscleAntagonist", "target": "TibialisPosterior" }, { "predicate": "subClassOf", "target": "Tibialis" } ] }
0
{ "document": "tibialis anterior A muscle that originates in the upper two-thirds of the lateral surface of the tibia and inserts into the medial cuneiform and first metatarsal bones of the foot. Its acts to invert the foot. It is situated on the lateral side of the tibia; it is thick and fleshy above, tendinous below. This muscle overlaps the anterior tibial vessels and deep peroneal nerve in the upper part of the leg. [WP,unvetted]. The M. tibialis cranialis is a muscle that flexes the tarsometatarsus. It originates on the craniodistal aspect of the femur and proximal tibiotarsus and inserts on the cranial surface of the tarsometarsus[EvoWiki]. [{'predicate': 'HasMuscleInsertion', 'target': 'MetatarsalBone'}, {'predicate': 'HasMuscleInsertion', 'target': 'DistalTarsalBone'}, {'predicate': 'HasMuscleAntagonist', 'target': 'Gastrocnemius'}, {'predicate': 'HasMuscleAntagonist', 'target': 'SoleusMuscle'}, {'predicate': 'HasMuscleAntagonist', 'target': 'TibialisPosterior'}, {'predicate': 'subClassOf', 'target': 'Tibialis'}]" }
{ "aliases": null, "definition": "Wasting of the tibialis anterior muscle.", "id": "TibialisAnteriorMuscleAtrophy", "label": "Tibialis anterior muscle atrophy", "logical_definition": null, "original_id": "HP:0011399", "relationships": [ { "predicate": "subClassOf", "target": "DistalLowerLimbAmyotrophy" } ] }
0
{ "document": "Tibialis anterior muscle atrophy Wasting of the tibialis anterior muscle. [{'predicate': 'subClassOf', 'target': 'DistalLowerLimbAmyotrophy'}]" }
{ "aliases": null, "definition": "Muscle weakness affecting the tibialis anterior muscle.", "id": "TibialisMuscleWeakness", "label": "Tibialis muscle weakness", "logical_definition": null, "original_id": "HP:0008963", "relationships": [ { "predicate": "subClassOf", "target": "DistalLowerLimbMuscleWeakness" } ] }
0
{ "document": "Tibialis muscle weakness Muscle weakness affecting the tibialis anterior muscle. [{'predicate': 'subClassOf', 'target': 'DistalLowerLimbMuscleWeakness'}]" }
{ "aliases": null, "definition": "The Tibialis posterior is the most central of all the leg muscles, and is located in the posterior compartment of the leg. It is the key stabilizing muscle of the lower leg. [WP,unvetted].", "id": "TibialisPosterior", "label": "tibialis posterior", "logical_definition": null, "original_id": "UBERON:0001667", "relationships": [ { "predicate": "InnervatedBy", "target": "TibialNerve" }, { "predicate": "HasMuscleOrigin", "target": "Tibia" }, { "predicate": "HasMuscleOrigin", "target": "Fibula" }, { "predicate": "HasMuscleInsertion", "target": "NavicularBoneOfPes" }, { "predicate": "HasMuscleInsertion", "target": "DistalTarsalBone1" }, { "predicate": "HasMuscleAntagonist", "target": "TibialisAnterior" }, { "predicate": "subClassOf", "target": "Tibialis" } ] }
0
{ "document": "tibialis posterior The Tibialis posterior is the most central of all the leg muscles, and is located in the posterior compartment of the leg. It is the key stabilizing muscle of the lower leg. [WP,unvetted]. [{'predicate': 'InnervatedBy', 'target': 'TibialNerve'}, {'predicate': 'HasMuscleOrigin', 'target': 'Tibia'}, {'predicate': 'HasMuscleOrigin', 'target': 'Fibula'}, {'predicate': 'HasMuscleInsertion', 'target': 'NavicularBoneOfPes'}, {'predicate': 'HasMuscleInsertion', 'target': 'DistalTarsalBone1'}, {'predicate': 'HasMuscleAntagonist', 'target': 'TibialisAnterior'}, {'predicate': 'subClassOf', 'target': 'Tibialis'}]" }
{ "aliases": null, "definition": null, "id": "TibiofibularDiastasis", "label": "Tibiofibular diastasis", "logical_definition": null, "original_id": "HP:0100535", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfFibulaMorphology" }, { "predicate": "subClassOf", "target": "AbnormalityOfTibiaMorphology" } ] }
0
{ "document": "Tibiofibular diastasis None [{'predicate': 'subClassOf', 'target': 'AbnormalityOfFibulaMorphology'}, {'predicate': 'subClassOf', 'target': 'AbnormalityOfTibiaMorphology'}]" }
{ "aliases": null, "definition": "A joint that connects the tibia and the fibula.", "id": "TibiofibularJoint", "label": "tibiofibular joint", "logical_definition": null, "original_id": "UBERON:0011112", "relationships": [ { "predicate": "subClassOf", "target": "Syndesmosis" } ] }
0
{ "document": "tibiofibular joint A joint that connects the tibia and the fibula. [{'predicate': 'subClassOf', 'target': 'Syndesmosis'}]" }
{ "aliases": null, "definition": "A skeletal joint that connects a tibia and connects a talus.", "id": "TibiotalarJoint", "label": "tibiotalar joint", "logical_definition": null, "original_id": "UBERON:0012076", "relationships": [ { "predicate": "subClassOf", "target": "AnkleJoint" } ] }
0
{ "document": "tibiotalar joint A skeletal joint that connects a tibia and connects a talus. [{'predicate': 'subClassOf', 'target': 'AnkleJoint'}]" }
{ "aliases": null, "definition": "Repeated, individually recognizable, intermittent movements or movement fragments that are almost always briefly suppressible and are usually associated with awareness of an urge to perform the movement.", "id": "Tics", "label": "Tics", "logical_definition": null, "original_id": "HP:0100033", "relationships": [ { "predicate": "subClassOf", "target": "CompulsiveBehaviors" } ] }
0
{ "document": "Tics Repeated, individually recognizable, intermittent movements or movement fragments that are almost always briefly suppressible and are usually associated with awareness of an urge to perform the movement. [{'predicate': 'subClassOf', 'target': 'CompulsiveBehaviors'}]" }
{ "aliases": null, "definition": "An abnormal appearance of hair under polarizing microscopy (using crossed polarizers), whereby hair shafts show striking alternating bright and dark bands, often referred to as tiger tail banding.", "id": "TigerTailBanding", "label": "Tiger tail banding", "logical_definition": null, "original_id": "HP:0045055", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalHairshaftMorphology" } ] }
0
{ "document": "Tiger tail banding An abnormal appearance of hair under polarizing microscopy (using crossed polarizers), whereby hair shafts show striking alternating bright and dark bands, often referred to as tiger tail banding. [{'predicate': 'subClassOf', 'target': 'AbnormalHairshaftMorphology'}]" }
{ "aliases": null, "definition": "A quality in which events occur in sequence.", "id": "Time", "label": "time", "logical_definition": null, "original_id": "PATO:0000165", "relationships": [ { "predicate": "subClassOf", "target": "PhysicalQuality" } ] }
0
{ "document": "time A quality in which events occur in sequence. [{'predicate': 'subClassOf', 'target': 'PhysicalQuality'}]" }
{ "aliases": null, "definition": "Tinnitus is an auditory perception that can be described as the experience of sound, in the ear or in the head, in the absence of external acoustic stimulation.", "id": "Tinnitus", "label": "Tinnitus", "logical_definition": null, "original_id": "HP:0000360", "relationships": [ { "predicate": "subClassOf", "target": "HearingAbnormality" } ] }
0
{ "document": "Tinnitus Tinnitus is an auditory perception that can be described as the experience of sound, in the ear or in the head, in the absence of external acoustic stimulation. [{'predicate': 'subClassOf', 'target': 'HearingAbnormality'}]" }
{ "aliases": null, "definition": "An abnormal gait pattern characterized by the failure of the heel to contact the floor at the onset of stance during gait.", "id": "TipToeGait", "label": "Tip-toe gait", "logical_definition": null, "original_id": "HP:0030051", "relationships": [ { "predicate": "subClassOf", "target": "GaitDisturbance" } ] }
0
{ "document": "Tip-toe gait An abnormal gait pattern characterized by the failure of the heel to contact the floor at the onset of stance during gait. [{'predicate': 'subClassOf', 'target': 'GaitDisturbance'}]" }
{ "aliases": null, "definition": "Segmental solidification of the glomerular tuft characterized by an adhesion at the tip of the glomerular tuft abutting the proximal tubular taek-off can be accompanied by increased extracellular matrix, causing glomerular capillary obliteration at the glomerular tip. Features including hyalinosis, foam cells, hypertrophy of overlying glomerular epithelial cells can also be observed.", "id": "TipVariantSegmentalGlomerulosclerosis", "label": "Tip variant segmental glomerulosclerosis", "logical_definition": null, "original_id": "HP:0033497", "relationships": [ { "predicate": "subClassOf", "target": "SegmentalGlomerulosclerosis" } ] }
0
{ "document": "Tip variant segmental glomerulosclerosis Segmental solidification of the glomerular tuft characterized by an adhesion at the tip of the glomerular tuft abutting the proximal tubular taek-off can be accompanied by increased extracellular matrix, causing glomerular capillary obliteration at the glomerular tip. Features including hyalinosis, foam cells, hypertrophy of overlying glomerular epithelial cells can also be observed. [{'predicate': 'subClassOf', 'target': 'SegmentalGlomerulosclerosis'}]" }
{ "aliases": null, "definition": "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation.", "id": "Tissue", "label": "tissue", "logical_definition": null, "original_id": "UBERON:0000479", "relationships": [ { "predicate": "PartOf", "target": "MulticellularOrganism" }, { "predicate": "HasPart", "target": "ExtracellularMatrix" }, { "predicate": "subClassOf", "target": "MulticellularAnatomicalStructure" } ] }
0
{ "document": "tissue Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. [{'predicate': 'PartOf', 'target': 'MulticellularOrganism'}, {'predicate': 'HasPart', 'target': 'ExtracellularMatrix'}, {'predicate': 'subClassOf', 'target': 'MulticellularAnatomicalStructure'}]" }
{ "aliases": null, "definition": "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.", "id": "TissueDevelopment", "label": "tissue development", "logical_definition": null, "original_id": "GO:0009888", "relationships": [ { "predicate": "subClassOf", "target": "AnatomicalStructureDevelopment" } ] }
0
{ "document": "tissue development The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. [{'predicate': 'subClassOf', 'target': 'AnatomicalStructureDevelopment'}]" }
{ "aliases": null, "definition": "A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.", "id": "TissueHomeostasis", "label": "tissue homeostasis", "logical_definition": null, "original_id": "GO:0001894", "relationships": [ { "predicate": "PartOf", "target": "MulticellularOrganismalLevelHomeostasis" }, { "predicate": "subClassOf", "target": "AnatomicalStructureHomeostasis" } ] }
0
{ "document": "tissue homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function. [{'predicate': 'PartOf', 'target': 'MulticellularOrganismalLevelHomeostasis'}, {'predicate': 'subClassOf', 'target': 'AnatomicalStructureHomeostasis'}]" }
{ "aliases": null, "definition": "Ischemia is defined as a restriction of arterial blood supply to a tissue associated with insufficient oxygenation to support the metabolis requirements of the tissue. Depending on the involved tissues, clinical manifestations may include pain, pallor, lack of pulse, coldness, paresthesia, and paralysis. Additional associated manifestations include hemodynamic parameters (reduced blood pressure distal to the site of restricted arterial supply) and angiographic evidence of arterial occclusion.", "id": "TissueIschemia", "label": "Tissue ischemia", "logical_definition": null, "original_id": "HP:0033401", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalArterialPhysiology" } ] }
0
{ "document": "Tissue ischemia Ischemia is defined as a restriction of arterial blood supply to a tissue associated with insufficient oxygenation to support the metabolis requirements of the tissue. Depending on the involved tissues, clinical manifestations may include pain, pallor, lack of pulse, coldness, paresthesia, and paralysis. Additional associated manifestations include hemodynamic parameters (reduced blood pressure distal to the site of restricted arterial supply) and angiographic evidence of arterial occclusion. [{'predicate': 'subClassOf', 'target': 'AbnormalArterialPhysiology'}]" }
{ "aliases": null, "definition": "The process in which the anatomical structures of a tissue are generated and organized.", "id": "TissueMorphogenesis", "label": "tissue morphogenesis", "logical_definition": null, "original_id": "GO:0048729", "relationships": [ { "predicate": "PartOf", "target": "TissueDevelopment" }, { "predicate": "subClassOf", "target": "AnatomicalStructureMorphogenesis" } ] }
0
{ "document": "tissue morphogenesis The process in which the anatomical structures of a tissue are generated and organized. [{'predicate': 'PartOf', 'target': 'TissueDevelopment'}, {'predicate': 'subClassOf', 'target': 'AnatomicalStructureMorphogenesis'}]" }
{ "aliases": null, "definition": "The regrowth of lost or destroyed tissues.", "id": "TissueRegeneration", "label": "tissue regeneration", "logical_definition": null, "original_id": "GO:0042246", "relationships": [ { "predicate": "subClassOf", "target": "Regeneration" }, { "predicate": "subClassOf", "target": "DevelopmentalGrowth" } ] }
0
{ "document": "tissue regeneration The regrowth of lost or destroyed tissues. [{'predicate': 'subClassOf', 'target': 'Regeneration'}, {'predicate': 'subClassOf', 'target': 'DevelopmentalGrowth'}]" }
{ "aliases": null, "definition": "The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.", "id": "TissueRemodeling", "label": "tissue remodeling", "logical_definition": null, "original_id": "GO:0048771", "relationships": [ { "predicate": "subClassOf", "target": "MulticellularOrganismalProcess" } ] }
0
{ "document": "tissue remodeling The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. [{'predicate': 'subClassOf', 'target': 'MulticellularOrganismalProcess'}]" }
{ "aliases": null, "definition": "A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.", "id": "TissueResidentMacrophage", "label": "tissue-resident macrophage", "logical_definition": null, "original_id": "CL:0000864", "relationships": [ { "predicate": "subClassOf", "target": "Macrophage" } ] }
0
{ "document": "tissue-resident macrophage A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. [{'predicate': 'subClassOf', 'target': 'Macrophage'}]" }
{ "aliases": null, "definition": "Degenerative process characteristic of a particular tissue.", "id": "TissueSpecificDegenerativeProcess", "label": "tissue specific degenerative process", "logical_definition": null, "original_id": "MPATH:25", "relationships": [ { "predicate": "subClassOf", "target": "ProcessOfDegenerativeChange" } ] }
0
{ "document": "tissue specific degenerative process Degenerative process characteristic of a particular tissue. [{'predicate': 'subClassOf', 'target': 'ProcessOfDegenerativeChange'}]" }
{ "aliases": null, "definition": null, "id": "Title", "label": "title", "logical_definition": null, "original_id": "dce:title", "relationships": null }
0
{ "document": "title None None" }
{ "aliases": null, "definition": "Nodding movement of the head or body.", "id": "Titubation", "label": "Titubation", "logical_definition": null, "original_id": "HP:0030187", "relationships": [ { "predicate": "subClassOf", "target": "ActionTremor" } ] }
0
{ "document": "Titubation Nodding movement of the head or body. [{'predicate': 'subClassOf', 'target': 'ActionTremor'}]" }
{ "aliases": null, "definition": "Bending or curvature of a toe in the tibial direction (i.e., towards the big toe).", "id": "ToeClinodactyly", "label": "Toe clinodactyly", "logical_definition": null, "original_id": "HP:0001863", "relationships": [ { "predicate": "subClassOf", "target": "Clinodactyly" }, { "predicate": "subClassOf", "target": "DeviationOfToes" } ] }
0
{ "document": "Toe clinodactyly Bending or curvature of a toe in the tibial direction (i.e., towards the big toe). [{'predicate': 'subClassOf', 'target': 'Clinodactyly'}, {'predicate': 'subClassOf', 'target': 'DeviationOfToes'}]" }
{ "aliases": null, "definition": "Toes appear swollen and plump owing to inflammation of the complete toe.", "id": "ToeDactylitis", "label": "Toe dactylitis", "logical_definition": null, "original_id": "HP:0031091", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalToeMorphology" } ] }
0
{ "document": "Toe dactylitis Toes appear swollen and plump owing to inflammation of the complete toe. [{'predicate': 'subClassOf', 'target': 'AbnormalToeMorphology'}]" }
{ "aliases": null, "definition": "Abnormal positioning of toe phalanges. Deformities of the lesser toes often occur gradually, though they can be brought on by trauma. The main adult sagittal plane deformities consist of claw toes, hammer toes and mallet toes. Axial plane deformities include crossover toes.", "id": "ToeDeformity", "label": "Toe deformity", "logical_definition": null, "original_id": "HP:0034398", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalToeMorphology" } ] }
0
{ "document": "Toe deformity Abnormal positioning of toe phalanges. Deformities of the lesser toes often occur gradually, though they can be brought on by trauma. The main adult sagittal plane deformities consist of claw toes, hammer toes and mallet toes. Axial plane deformities include crossover toes. [{'predicate': 'subClassOf', 'target': 'AbnormalToeMorphology'}]" }
{ "aliases": null, "definition": "Atrophy of the extensor digitorum longus muscles, which mediate extension of the toes.", "id": "ToeExtensorAmyotrophy", "label": "Toe extensor amyotrophy", "logical_definition": null, "original_id": "HP:0011916", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfTheFootMusculature" } ] }
0
{ "document": "Toe extensor amyotrophy Atrophy of the extensor digitorum longus muscles, which mediate extension of the toes. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTheFootMusculature'}]" }
{ "aliases": null, "definition": "Lack of full passive range of motion (restrictions in flexion, extension, or other movements) of a toe joint resulting from structural changes of non-bony tissues, such as muscles, tendons, ligaments, joint capsules and/or skin.", "id": "ToeJointContracture", "label": "Toe joint contracture", "logical_definition": null, "original_id": "HP:0034675", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalToeMorphology" } ] }
0
{ "document": "Toe joint contracture Lack of full passive range of motion (restrictions in flexion, extension, or other movements) of a toe joint resulting from structural changes of non-bony tissues, such as muscles, tendons, ligaments, joint capsules and/or skin. [{'predicate': 'subClassOf', 'target': 'AbnormalToeMorphology'}]" }
{ "aliases": null, "definition": "An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the toe.", "id": "ToePain", "label": "Toe pain", "logical_definition": null, "original_id": "HP:0030841", "relationships": [ { "predicate": "subClassOf", "target": "LowerLimbPain" } ] }
0
{ "document": "Toe pain An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the toe. [{'predicate': 'subClassOf', 'target': 'LowerLimbPain'}]" }
{ "aliases": null, "definition": "Webbing or fusion of the toes, involving soft parts only or including bone structure. Bony fusions are referred to as \"bony\" Syndactyly if the fusion occurs in a radio-ulnar axis. Fusions of bones of the toes in a proximo-distal axis are referred to as \"Symphalangism\".", "id": "ToeSyndactyly", "label": "Toe syndactyly", "logical_definition": null, "original_id": "HP:0001770", "relationships": [ { "predicate": "subClassOf", "target": "Syndactyly" }, { "predicate": "subClassOf", "target": "AbnormalToeMorphology" } ] }
0
{ "document": "Toe syndactyly Webbing or fusion of the toes, involving soft parts only or including bone structure. Bony fusions are referred to as \"bony\" Syndactyly if the fusion occurs in a radio-ulnar axis. Fusions of bones of the toes in a proximo-distal axis are referred to as \"Symphalangism\". [{'predicate': 'subClassOf', 'target': 'Syndactyly'}, {'predicate': 'subClassOf', 'target': 'AbnormalToeMorphology'}]" }
{ "aliases": null, "definition": "An abnormality of the development of the toenails.", "id": "ToenailDysplasia", "label": "Toenail dysplasia", "logical_definition": null, "original_id": "HP:0100797", "relationships": [ { "predicate": "subClassOf", "target": "NailDysplasia" }, { "predicate": "subClassOf", "target": "AbnormalToenailMorphology" } ] }
0
{ "document": "Toenail dysplasia An abnormality of the development of the toenails. [{'predicate': 'subClassOf', 'target': 'NailDysplasia'}, {'predicate': 'subClassOf', 'target': 'AbnormalToenailMorphology'}]" }
{ "aliases": null, "definition": "Painless and spontaneous separation of a toenail from the nail bed.", "id": "ToenailOnycholysis", "label": "Toenail onycholysis", "logical_definition": null, "original_id": "HP:0040040", "relationships": [ { "predicate": "subClassOf", "target": "Onycholysis" }, { "predicate": "subClassOf", "target": "AbnormalToenailMorphology" } ] }
0
{ "document": "Toenail onycholysis Painless and spontaneous separation of a toenail from the nail bed. [{'predicate': 'subClassOf', 'target': 'Onycholysis'}, {'predicate': 'subClassOf', 'target': 'AbnormalToenailMorphology'}]" }
{ "aliases": null, "definition": "A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.", "id": "ToleranceInduction", "label": "tolerance induction", "logical_definition": null, "original_id": "GO:0002507", "relationships": [ { "predicate": "PartOf", "target": "ImmuneSystemDevelopment" }, { "predicate": "subClassOf", "target": "ImmuneSystemProcess" } ] }
0
{ "document": "tolerance induction A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it. [{'predicate': 'PartOf', 'target': 'ImmuneSystemDevelopment'}, {'predicate': 'subClassOf', 'target': 'ImmuneSystemProcess'}]" }
{ "aliases": null, "definition": "Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.", "id": "ToleranceInductionDependentUponImmuneResponse", "label": "tolerance induction dependent upon immune response", "logical_definition": null, "original_id": "GO:0002461", "relationships": [ { "predicate": "subClassOf", "target": "AdaptiveImmuneResponseBasedOnSomaticRecombinationOfImmuneReceptorsBuiltFromImmunoglobulinSuperfamilyDomains" }, { "predicate": "subClassOf", "target": "ToleranceInduction" } ] }
0
{ "document": "tolerance induction dependent upon immune response Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation. [{'predicate': 'subClassOf', 'target': 'AdaptiveImmuneResponseBasedOnSomaticRecombinationOfImmuneReceptorsBuiltFromImmunoglobulinSuperfamilyDomains'}, {'predicate': 'subClassOf', 'target': 'ToleranceInduction'}]" }
{ "aliases": null, "definition": "The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.", "id": "Toluene", "label": "toluene", "logical_definition": null, "original_id": "CHEBI:17578", "relationships": [ { "predicate": "HasRole", "target": "NonPolarSolvent" }, { "predicate": "HasRole", "target": "CholinergicAntagonist" }, { "predicate": "HasRole", "target": "Neurotoxin" }, { "predicate": "HasRole", "target": "FuelAdditive" }, { "predicate": "subClassOf", "target": "VolatileOrganicCompound" }, { "predicate": "subClassOf", "target": "Toluenes" }, { "predicate": "subClassOf", "target": "Methylbenzene" } ] }
0
{ "document": "toluene The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent. [{'predicate': 'HasRole', 'target': 'NonPolarSolvent'}, {'predicate': 'HasRole', 'target': 'CholinergicAntagonist'}, {'predicate': 'HasRole', 'target': 'Neurotoxin'}, {'predicate': 'HasRole', 'target': 'FuelAdditive'}, {'predicate': 'subClassOf', 'target': 'VolatileOrganicCompound'}, {'predicate': 'subClassOf', 'target': 'Toluenes'}, {'predicate': 'subClassOf', 'target': 'Methylbenzene'}]" }
{ "aliases": null, "definition": "Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group.", "id": "Toluenes", "label": "toluenes", "logical_definition": null, "original_id": "CHEBI:27024", "relationships": [ { "predicate": "subClassOf", "target": "Benzenes" } ] }
0
{ "document": "toluenes Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group. [{'predicate': 'subClassOf', 'target': 'Benzenes'}]" }
{ "aliases": null, "definition": null, "id": "TombstoneShapedProximalPhalanges", "label": "Tombstone-shaped proximal phalanges", "logical_definition": null, "original_id": "HP:0006060", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalProximalPhalanxMorphologyOfTheHand" } ] }
0
{ "document": "Tombstone-shaped proximal phalanges None [{'predicate': 'subClassOf', 'target': 'AbnormalProximalPhalanxMorphologyOfTheHand'}]" }
{ "aliases": null, "definition": "A muscular organ in the floor of the mouth.", "id": "Tongue", "label": "tongue", "logical_definition": null, "original_id": "UBERON:0001723", "relationships": [ { "predicate": "PartOf", "target": "Mouth" }, { "predicate": "PartOf", "target": "GustatorySystem" }, { "predicate": "DevelopsFrom", "target": "PharyngealArchSystem" }, { "predicate": "AdjacentTo", "target": "OralOpening" }, { "predicate": "HasDevelopmentalContributionFrom", "target": "LingualSwellings" }, { "predicate": "HasDevelopmentalContributionFrom", "target": "MedianLingualSwelling" }, { "predicate": "HasDevelopmentalContributionFrom", "target": "LateralLingualSwelling" }, { "predicate": "ContributesToMorphologyOf", "target": "DigestiveSystem" }, { "predicate": "ImmediateTransformationOf", "target": "FutureTongue" }, { "predicate": "subClassOf", "target": "SenseOrgan" } ] }
0
{ "document": "tongue A muscular organ in the floor of the mouth. [{'predicate': 'PartOf', 'target': 'Mouth'}, {'predicate': 'PartOf', 'target': 'GustatorySystem'}, {'predicate': 'DevelopsFrom', 'target': 'PharyngealArchSystem'}, {'predicate': 'AdjacentTo', 'target': 'OralOpening'}, {'predicate': 'HasDevelopmentalContributionFrom', 'target': 'LingualSwellings'}, {'predicate': 'HasDevelopmentalContributionFrom', 'target': 'MedianLingualSwelling'}, {'predicate': 'HasDevelopmentalContributionFrom', 'target': 'LateralLingualSwelling'}, {'predicate': 'ContributesToMorphologyOf', 'target': 'DigestiveSystem'}, {'predicate': 'ImmediateTransformationOf', 'target': 'FutureTongue'}, {'predicate': 'subClassOf', 'target': 'SenseOrgan'}]" }
{ "aliases": null, "definition": "Wasting of the tongue.", "id": "TongueAtrophy", "label": "Tongue atrophy", "logical_definition": null, "original_id": "HP:0012473", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalTongueMorphology" } ] }
0
{ "document": "Tongue atrophy Wasting of the tongue. [{'predicate': 'subClassOf', 'target': 'AbnormalTongueMorphology'}]" }
{ "aliases": null, "definition": "An abnormal accumulation of fluid and swelling in the tongue.", "id": "TongueEdema", "label": "Tongue edema", "logical_definition": null, "original_id": "HP:0040315", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfTheTongue" }, { "predicate": "subClassOf", "target": "Edema" } ] }
0
{ "document": "Tongue edema An abnormal accumulation of fluid and swelling in the tongue. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTheTongue'}, {'predicate': 'subClassOf', 'target': 'Edema'}]" }
{ "aliases": null, "definition": "Fasciculations or fibrillation affecting the tongue muscle.", "id": "TongueFasciculations", "label": "Tongue fasciculations", "logical_definition": null, "original_id": "HP:0001308", "relationships": [ { "predicate": "subClassOf", "target": "Fasciculations" }, { "predicate": "subClassOf", "target": "MuscleFibrillation" }, { "predicate": "subClassOf", "target": "AbnormalTonguePhysiology" } ] }
0
{ "document": "Tongue fasciculations Fasciculations or fibrillation affecting the tongue muscle. [{'predicate': 'subClassOf', 'target': 'Fasciculations'}, {'predicate': 'subClassOf', 'target': 'MuscleFibrillation'}, {'predicate': 'subClassOf', 'target': 'AbnormalTonguePhysiology'}]" }
{ "aliases": null, "definition": "A keratinized stratified squamous epithelium that is part of a tongue.", "id": "TongueKeratinizedEpithelium", "label": "tongue keratinized epithelium", "logical_definition": null, "original_id": "UBERON:0004650", "relationships": null }
0
{ "document": "tongue keratinized epithelium A keratinized stratified squamous epithelium that is part of a tongue. None" }
{ "aliases": null, "definition": "A tongue-like protusion from the anterior aspect of lumbar vertebral bodies.", "id": "TongueLikeLumbarVertebralDeformities", "label": "Tongue-like lumbar vertebral deformities", "logical_definition": null, "original_id": "HP:0005680", "relationships": [ { "predicate": "subClassOf", "target": "AnteriorBeakingOfLumbarVertebrae" } ] }
0
{ "document": "Tongue-like lumbar vertebral deformities A tongue-like protusion from the anterior aspect of lumbar vertebral bodies. [{'predicate': 'subClassOf', 'target': 'AnteriorBeakingOfLumbarVertebrae'}]" }
{ "aliases": null, "definition": "The muscular portion of the tongue.", "id": "TongueMuscle", "label": "tongue muscle", "logical_definition": null, "original_id": "UBERON:0000378", "relationships": [ { "predicate": "PartOf", "target": "Mouth" }, { "predicate": "DevelopsFrom", "target": "HeadSomite" }, { "predicate": "ContributesToMorphologyOf", "target": "Tongue" }, { "predicate": "subClassOf", "target": "SkeletalMuscleOrgan" } ] }
0
{ "document": "tongue muscle The muscular portion of the tongue. [{'predicate': 'PartOf', 'target': 'Mouth'}, {'predicate': 'DevelopsFrom', 'target': 'HeadSomite'}, {'predicate': 'ContributesToMorphologyOf', 'target': 'Tongue'}, {'predicate': 'subClassOf', 'target': 'SkeletalMuscleOrgan'}]" }
{ "aliases": null, "definition": "A skeletal muscle cell that is part of the tongue.", "id": "TongueMuscleCell", "label": "tongue muscle cell", "logical_definition": null, "original_id": "CL:0002673", "relationships": null }
0
{ "document": "tongue muscle cell A skeletal muscle cell that is part of the tongue. None" }
{ "aliases": null, "definition": "A myxoma (benign soft tissue neoplasm characterized by the presence of spindle and stellate cells, lobulated growth pattern, and myxoid stroma formation) localized in the tongue.", "id": "TongueMyxoma", "label": "Tongue myxoma", "logical_definition": null, "original_id": "HP:0034668", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalTongueMorphology" } ] }
0
{ "document": "Tongue myxoma A myxoma (benign soft tissue neoplasm characterized by the presence of spindle and stellate cells, lobulated growth pattern, and myxoid stroma formation) localized in the tongue. [{'predicate': 'subClassOf', 'target': 'AbnormalTongueMorphology'}]" }
{ "aliases": null, "definition": "A neurofibroma (benign peripheral nerve sheath tumor) localized in the tongue.", "id": "TongueNeurofibroma", "label": "Tongue neurofibroma", "logical_definition": null, "original_id": "HP:0034762", "relationships": [ { "predicate": "subClassOf", "target": "NeurofibromaByAnatomicalLocation" } ] }
0
{ "document": "Tongue neurofibroma A neurofibroma (benign peripheral nerve sheath tumor) localized in the tongue. [{'predicate': 'subClassOf', 'target': 'NeurofibromaByAnatomicalLocation'}]" }
{ "aliases": null, "definition": null, "id": "TongueNodules", "label": "Tongue nodules", "logical_definition": null, "original_id": "HP:0000199", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalTongueMorphology" } ] }
0
{ "document": "Tongue nodules None [{'predicate': 'subClassOf', 'target': 'AbnormalTongueMorphology'}]" }
{ "aliases": null, "definition": "An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the tongue.", "id": "TonguePain", "label": "Tongue pain", "logical_definition": null, "original_id": "HP:0030811", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalTonguePhysiology" }, { "predicate": "subClassOf", "target": "PainInHeadAndNeckRegion" } ] }
0
{ "document": "Tongue pain An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the tongue. [{'predicate': 'subClassOf', 'target': 'AbnormalTonguePhysiology'}, {'predicate': 'subClassOf', 'target': 'PainInHeadAndNeckRegion'}]" }